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Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high-fat diet
(Molecular and Cellular Biochemistry, 2017)
The aim of this study was to investigate whether the presence of endogenous estradiol alters the effects of a high-fat (HF) diet on activity/expression of the cardiac Na+/K+-ATPase, via PI3K/IRS and RhoA/ROCK signalling ...
Interaction of some pd(II) complexes with Na+/K+-ATPase: Inhibition, kinetics, prevention and recovery
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2006)
The aim of this work was to investigate the influence of [PdCl4](2-), [PdCl(dien)](+) and [PdCl(Me(4)dien)](+) complexes on Na+/K+-ATPase activity. The dose-dependent inhibition curves were obtained in all cases. IC50 ...
Regulation of hepatic Na+/K+-ATPase in obese female and male rats: involvement of ERK1/2, AMPK, and Rho/ROCK
(Molecular and Cellular Biochemistry, 2018)
In this study, we assessed whether the disturbed regulation of sodium/potassium-adenosine-triphosphatase (Na+/K+-ATPase) occurs as a consequence of obesity-induced IR in sex-specific manner. We also assessed whether ...
Interaction of Gold Nanoparticles with Rat Brain Synaptosomal Plasma Membrane Na+/K+ - Atpase and Mg2+-Atpase
(Digest Journal of Nanomaterials and Biostructures, 2012)
The aim of the work was to investigate the interaction between borate capped gold nanoparticles (NPs) and the rat brain synaptosomal plasma membranes (SPM), as well as the effects of these NPs on SPM Na+/K+ - ATPase and ...
Prevention and recovery of CuSO4-induced inhibition of Na+/K+-ATPase and Mg2+-ATPase in rat brain synaptosomes by EDTA
(Toxicology Letters, 1999)
Enzymatic activities of Na+/K+-ATPase and Mg2+-ATPase from rat brain synaptic plasma membrane were studied in the absence and presence of EDTA. The aim of the study was to examine the ability of this strong chelator to ...
Mechanism of Na+/K+-Atpase and Mg2+-Atpase Inhibition By Metal Ions and Complexes / Mehanizam inhibicije Na+/K+–ATPaze i Mg2+–ATPaze metalnim jonima i kompleksima
(Hemijska industrija, 2009)
The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase and Mg2+-ATPase activity, the enzymes playing a key role in the active transport of monovalent cations (Na+ and K+) across the ...
The activity of erythrocyte and brain Na+/K+ and Mg2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration
(Molecular and Cellular Biochemistry, 2009)
Hyperhomocysteinemia is associated with various pathologies including cardiovascular disease, stroke, and cognitive dysfunctions. Systemic administration of homocysteine can trigger seizures in animals, and patients with ...
Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2004)
Inhibition of Na+/K+-ATPase activity from human erythrocyte membranes and commercial porcine cerebral cortex by in vitro single and simultaneous exposure to digoxin and gitoxin was investigated to elucidate the difference ...
The influence of potassium ion (K+) on digoxin-induced inhibition of porcine cerebral cortex Na+/K+-ATPase
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2006)
The in vitro influence of potassium ion modulations, in the concentration range 2mM - 500mM, on digoxin-induced inhibition of porcine cerebral cortex Na+/K+-ATPase activity was studied. The response of enzymatic activity ...
Chemical aspects of the influence of cobalt ions on ATPase activity
(Journal of the Serbian Chemical Society, 2000)
The influence of Co2+ ions on the activities of Na+/K+-ATPase and Mg2+-ATPase, enzymes from rat brain synaptic plasma membrane, was studied. The aim of this study was to investigate the inhibition of both ATPases activities ...