Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database
2009
Autori
Sokka, T.Kautiainen, H.
Pincus, T.
Toloza, S.
Castelar Pinheiro, G. da Rocha
Lazovskis, J.
Hetland, M. L.
Peets, T.
Immonen, K.
Maillefert, J. F.
Drosos, A. A.
Alten, R.
Pohl, C.
Rojkovich, B.
Bresnihan, B.
Minnock, P.
Cazzato, M.
Bombardieri, S.
Rexhepi, S.
Rexhepi, M.
Andersone, D.
Stropuviene, S.
Huisman, M.
Sierakowski, S.
Karateev, D.
Skakic, V.
Naranjo, A.
Baecklund, E.
Henrohn, D.
Gogus, F.
Badsha, H.
Mofti, A.
Taylor, P.
McClinton, C.
Yazici, Y.
Članak u časopisu
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Objective: To analyse associations between the clinical status of patients with rheumatoid arthritis ( RA) and the gross domestic product (GDP) of their resident country. Methods: The Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) cohort includes clinical and questionnaire data from 6004 patients who were seen in usual care at 70 rheumatology clinics in 25 countries as of April 2008, including 18 European countries. Demographic variables, clinical characteristics, RA disease activity measures, including the disease activity score in 28 joints (DAS28), and treatment-related variables were analysed according to GDP per capita, including 14 high GDP countries with GDP per capita greater than US$ 24 000 and 11 low GDP countries with GDP per capita less than US$ 11 000. Results: Disease activity DAS28 ranged between 3.1 and 6.0 among the 25 countries and was significantly associated with GDP (r = -0.78, 95% CI -0.56 to -0.90, r(2) = 61%). Disease activity ...levels differed substantially between high GDP and low GDP countries at much greater levels than according to whether patients were currently taking or not taking methotrexate, prednisone and/or biological agents. Conclusions: The clinical status of patients with RA was correlated significantly with GDP among 25 mostly European countries according to all disease measures, associated only modestly with the current use of antirheumatic medications. The burden of arthritis appears substantially greater in low GDP than in high GDP countries. These findings may alert healthcare professionals and designers of health policy towards improving the clinical status of patients with RA in all countries.
Izvor:
Annals of the Rheumatic Diseases, 2009, 68, 11, 1666-1672Finansiranje / projekti:
- Central Finland Health Care District, Heinola Rheumatism Foundation Hospital (EVO grants)
DOI: 10.1136/ard.2009.109983
ISSN: 0003-4967
PubMed: 19643759
WoS: 000270700900003
Scopus: 2-s2.0-68049127280
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Sokka, T. AU - Kautiainen, H. AU - Pincus, T. AU - Toloza, S. AU - Castelar Pinheiro, G. da Rocha AU - Lazovskis, J. AU - Hetland, M. L. AU - Peets, T. AU - Immonen, K. AU - Maillefert, J. F. AU - Drosos, A. A. AU - Alten, R. AU - Pohl, C. AU - Rojkovich, B. AU - Bresnihan, B. AU - Minnock, P. AU - Cazzato, M. AU - Bombardieri, S. AU - Rexhepi, S. AU - Rexhepi, M. AU - Andersone, D. AU - Stropuviene, S. AU - Huisman, M. AU - Sierakowski, S. AU - Karateev, D. AU - Skakic, V. AU - Naranjo, A. AU - Baecklund, E. AU - Henrohn, D. AU - Gogus, F. AU - Badsha, H. AU - Mofti, A. AU - Taylor, P. AU - McClinton, C. AU - Yazici, Y. PY - 2009 UR - https://vinar.vin.bg.ac.rs/handle/123456789/3800 AB - Objective: To analyse associations between the clinical status of patients with rheumatoid arthritis ( RA) and the gross domestic product (GDP) of their resident country. Methods: The Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) cohort includes clinical and questionnaire data from 6004 patients who were seen in usual care at 70 rheumatology clinics in 25 countries as of April 2008, including 18 European countries. Demographic variables, clinical characteristics, RA disease activity measures, including the disease activity score in 28 joints (DAS28), and treatment-related variables were analysed according to GDP per capita, including 14 high GDP countries with GDP per capita greater than US$ 24 000 and 11 low GDP countries with GDP per capita less than US$ 11 000. Results: Disease activity DAS28 ranged between 3.1 and 6.0 among the 25 countries and was significantly associated with GDP (r = -0.78, 95% CI -0.56 to -0.90, r(2) = 61%). Disease activity levels differed substantially between high GDP and low GDP countries at much greater levels than according to whether patients were currently taking or not taking methotrexate, prednisone and/or biological agents. Conclusions: The clinical status of patients with RA was correlated significantly with GDP among 25 mostly European countries according to all disease measures, associated only modestly with the current use of antirheumatic medications. The burden of arthritis appears substantially greater in low GDP than in high GDP countries. These findings may alert healthcare professionals and designers of health policy towards improving the clinical status of patients with RA in all countries. T2 - Annals of the Rheumatic Diseases T1 - Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database VL - 68 IS - 11 SP - 1666 EP - 1672 DO - 10.1136/ard.2009.109983 ER -
@article{ author = "Sokka, T. and Kautiainen, H. and Pincus, T. and Toloza, S. and Castelar Pinheiro, G. da Rocha and Lazovskis, J. and Hetland, M. L. and Peets, T. and Immonen, K. and Maillefert, J. F. and Drosos, A. A. and Alten, R. and Pohl, C. and Rojkovich, B. and Bresnihan, B. and Minnock, P. and Cazzato, M. and Bombardieri, S. and Rexhepi, S. and Rexhepi, M. and Andersone, D. and Stropuviene, S. and Huisman, M. and Sierakowski, S. and Karateev, D. and Skakic, V. and Naranjo, A. and Baecklund, E. and Henrohn, D. and Gogus, F. and Badsha, H. and Mofti, A. and Taylor, P. and McClinton, C. and Yazici, Y.", year = "2009", abstract = "Objective: To analyse associations between the clinical status of patients with rheumatoid arthritis ( RA) and the gross domestic product (GDP) of their resident country. Methods: The Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) cohort includes clinical and questionnaire data from 6004 patients who were seen in usual care at 70 rheumatology clinics in 25 countries as of April 2008, including 18 European countries. Demographic variables, clinical characteristics, RA disease activity measures, including the disease activity score in 28 joints (DAS28), and treatment-related variables were analysed according to GDP per capita, including 14 high GDP countries with GDP per capita greater than US$ 24 000 and 11 low GDP countries with GDP per capita less than US$ 11 000. Results: Disease activity DAS28 ranged between 3.1 and 6.0 among the 25 countries and was significantly associated with GDP (r = -0.78, 95% CI -0.56 to -0.90, r(2) = 61%). Disease activity levels differed substantially between high GDP and low GDP countries at much greater levels than according to whether patients were currently taking or not taking methotrexate, prednisone and/or biological agents. Conclusions: The clinical status of patients with RA was correlated significantly with GDP among 25 mostly European countries according to all disease measures, associated only modestly with the current use of antirheumatic medications. The burden of arthritis appears substantially greater in low GDP than in high GDP countries. These findings may alert healthcare professionals and designers of health policy towards improving the clinical status of patients with RA in all countries.", journal = "Annals of the Rheumatic Diseases", title = "Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database", volume = "68", number = "11", pages = "1666-1672", doi = "10.1136/ard.2009.109983" }
Sokka, T., Kautiainen, H., Pincus, T., Toloza, S., Castelar Pinheiro, G. d. R., Lazovskis, J., Hetland, M. L., Peets, T., Immonen, K., Maillefert, J. F., Drosos, A. A., Alten, R., Pohl, C., Rojkovich, B., Bresnihan, B., Minnock, P., Cazzato, M., Bombardieri, S., Rexhepi, S., Rexhepi, M., Andersone, D., Stropuviene, S., Huisman, M., Sierakowski, S., Karateev, D., Skakic, V., Naranjo, A., Baecklund, E., Henrohn, D., Gogus, F., Badsha, H., Mofti, A., Taylor, P., McClinton, C.,& Yazici, Y.. (2009). Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database. in Annals of the Rheumatic Diseases, 68(11), 1666-1672. https://doi.org/10.1136/ard.2009.109983
Sokka T, Kautiainen H, Pincus T, Toloza S, Castelar Pinheiro GDR, Lazovskis J, Hetland ML, Peets T, Immonen K, Maillefert JF, Drosos AA, Alten R, Pohl C, Rojkovich B, Bresnihan B, Minnock P, Cazzato M, Bombardieri S, Rexhepi S, Rexhepi M, Andersone D, Stropuviene S, Huisman M, Sierakowski S, Karateev D, Skakic V, Naranjo A, Baecklund E, Henrohn D, Gogus F, Badsha H, Mofti A, Taylor P, McClinton C, Yazici Y. Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database. in Annals of the Rheumatic Diseases. 2009;68(11):1666-1672. doi:10.1136/ard.2009.109983 .
Sokka, T., Kautiainen, H., Pincus, T., Toloza, S., Castelar Pinheiro, G. da Rocha, Lazovskis, J., Hetland, M. L., Peets, T., Immonen, K., Maillefert, J. F., Drosos, A. A., Alten, R., Pohl, C., Rojkovich, B., Bresnihan, B., Minnock, P., Cazzato, M., Bombardieri, S., Rexhepi, S., Rexhepi, M., Andersone, D., Stropuviene, S., Huisman, M., Sierakowski, S., Karateev, D., Skakic, V., Naranjo, A., Baecklund, E., Henrohn, D., Gogus, F., Badsha, H., Mofti, A., Taylor, P., McClinton, C., Yazici, Y., "Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database" in Annals of the Rheumatic Diseases, 68, no. 11 (2009):1666-1672, https://doi.org/10.1136/ard.2009.109983 . .