Technetium-99m in Production and Use
Апстракт
Several types of generators have been developed for the production of (99m)Tc. Due to its excelent performances, the chromatographic type, based on the fission-produced (99)Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-(99m)Tc. However, due to the known disadvantages of the production of (n, f)(99)Mo, attempts are made to avoid uranium fission. The technologies based on (n, gamma)(99)Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce (99)Mo (or directly (99m)Tc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of (99m)Tc-eluate to the inactive components comprised in the cold kits. The chromatographic (n, f)(99)Mo/(99m)Tc generator and several (99m)Tc-radiopharmaceuticals have been developed and are regularly produced in the Vinca Institut...e of Nuclear Sciences (Laboratory for Radioisotopes).
Кључне речи:
technetium-99m / molybdenum-99 / technetium-99m-generator / technetium-99m-radiopharmaceuticalsИзвор:
Nuclear technology and radiation protection, 2009, 24, 1, 68-73
DOI: 10.2298/NTRP0901068V
ISSN: 1451-3994
WoS: 000265688100009
Scopus: 2-s2.0-70349211642
Колекције
Институција/група
VinčaTY - JOUR AU - Vučina, Jurij L. AU - Nikolić, Nadežda S. AU - Petrović, Đokica PY - 2009 UR - https://vinar.vin.bg.ac.rs/handle/123456789/3687 AB - Several types of generators have been developed for the production of (99m)Tc. Due to its excelent performances, the chromatographic type, based on the fission-produced (99)Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-(99m)Tc. However, due to the known disadvantages of the production of (n, f)(99)Mo, attempts are made to avoid uranium fission. The technologies based on (n, gamma)(99)Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce (99)Mo (or directly (99m)Tc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of (99m)Tc-eluate to the inactive components comprised in the cold kits. The chromatographic (n, f)(99)Mo/(99m)Tc generator and several (99m)Tc-radiopharmaceuticals have been developed and are regularly produced in the Vinca Institute of Nuclear Sciences (Laboratory for Radioisotopes). T2 - Nuclear technology and radiation protection T1 - Technetium-99m in Production and Use VL - 24 IS - 1 SP - 68 EP - 73 DO - 10.2298/NTRP0901068V ER -
@article{ author = "Vučina, Jurij L. and Nikolić, Nadežda S. and Petrović, Đokica", year = "2009", abstract = "Several types of generators have been developed for the production of (99m)Tc. Due to its excelent performances, the chromatographic type, based on the fission-produced (99)Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-(99m)Tc. However, due to the known disadvantages of the production of (n, f)(99)Mo, attempts are made to avoid uranium fission. The technologies based on (n, gamma)(99)Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce (99)Mo (or directly (99m)Tc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of (99m)Tc-eluate to the inactive components comprised in the cold kits. The chromatographic (n, f)(99)Mo/(99m)Tc generator and several (99m)Tc-radiopharmaceuticals have been developed and are regularly produced in the Vinca Institute of Nuclear Sciences (Laboratory for Radioisotopes).", journal = "Nuclear technology and radiation protection", title = "Technetium-99m in Production and Use", volume = "24", number = "1", pages = "68-73", doi = "10.2298/NTRP0901068V" }
Vučina, J. L., Nikolić, N. S.,& Petrović, Đ.. (2009). Technetium-99m in Production and Use. in Nuclear technology and radiation protection, 24(1), 68-73. https://doi.org/10.2298/NTRP0901068V
Vučina JL, Nikolić NS, Petrović Đ. Technetium-99m in Production and Use. in Nuclear technology and radiation protection. 2009;24(1):68-73. doi:10.2298/NTRP0901068V .
Vučina, Jurij L., Nikolić, Nadežda S., Petrović, Đokica, "Technetium-99m in Production and Use" in Nuclear technology and radiation protection, 24, no. 1 (2009):68-73, https://doi.org/10.2298/NTRP0901068V . .