Show simple item record

dc.creatorJevtic, M.
dc.creatorRadulovic, A.
dc.creatorIgnjatović, Nenad L.
dc.creatorMitrić, Miodrag
dc.creatorUskoković, Dragan
dc.date.accessioned2018-03-01T20:38:40Z
dc.date.available2018-03-01T20:38:40Z
dc.date.issued2009
dc.identifier.issn1742-7061 (print)
dc.identifier.issn1878-7568 (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/3597
dc.description.abstractAn ultrasound field was applied to obtain PLGA/HAp biocomposite nanospheres. Formulation of PLGA/HAp, composite revealed significant dependence of the morphology of the obtained composite on synthesis parameters, like the intensity of applied ultrasonic field, polymeric and ceramic parts wt.% ratio in the composite, temperature of the medium, type of surfactant, and the sequence of steps in the formation of PLGA/HAp. Optimal parameters for the formation of PLGA/HAp included a lower content of the ceramic phase (PLGA/HAp = 90: 10), higher power of ultrasonic field (P = 142.4 W), lower temperature of the medium during ultrasonic treatment (T = 8 degrees C), dilute solution of PVP as surfactant and dispersion of hydroxyapatite in polymer solution in order to achieve required homogeneity before the formulation of the composite. The morphology of PLGA/HAp particles synthesized under these conditions was highly regular: sphere-like, with particles of very small dimensions (150-320 nm), highly uniform particle size distribution and characteristic planar spatial self-organization. These characteristics indicate significant improvements in PLGA/HAp composite resulting from ultrasonic method. (C) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.en
dc.relationMinistry of Science and Technological Development of the Republic of Serbia [142006]
dc.rightsrestrictedAccessen
dc.sourceActa Biomaterialiaen
dc.subjectBiocompositeen
dc.subjectPLGA/hydroxyapatiteen
dc.subjectNanospheresen
dc.subjectCore-shellen
dc.subjectUltrasonic methoden
dc.titleControlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiationen
dc.typearticleen
dcterms.abstractУскоковић, Драган; Јевтиц, М.; Радуловиц, A.; Игњатовић Ненад; Митрић Миодраг;
dc.citation.volume5
dc.citation.issue1
dc.citation.spage208
dc.citation.epage218
dc.identifier.wos000261922400022
dc.identifier.doi10.1016/j.actbio.2008.07.026
dc.citation.rankM21a
dc.identifier.pmid18753023
dc.identifier.scopus2-s2.0-56349094659


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record