Particle size analysis: (90)Y and (99m)Tc-labelled colloids
2008
Преузимање 🢃
Аутори
Janković, DrinaMaksin, Tatjana N.
Đokić, Divna Đ.
Milonjić, Slobodan K.
Nikolić, Nadežda S.
Mirković, Marija D.
Vranješ-Đurić, Sanja
Чланак у часопису
Метаподаци
Приказ свих података о документуАпстракт
Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for diagnosis and therapeutic purposes in nuclear medicine. Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle-size distribution of (90)Y- and (99m)Tc-labelled antimony trisulfide (Sb(2)S(3)) and tin colloids (Sn-colloid). (90)Y-Sb(2)S(3) and (99m)Tc-Sb(2)S(3) were found to have a diameter of 28.92 +/- 0.14 and 35.61 +/- 0.11 nm, respectively, by PCS. By TEM, (90)Y-Sb(2)S(3) particles were measured to be 14.33 +/- 0.09 nm. (90)Y-labelled Sn colloid were found to exist with a d(v(max1)) of 805 nm and a d(v(max2)) of 2590 nm, by PCS, whereas (99m)Tc-Sn colloid was shown to have more than 80% of radioactive particles of approximately 910 nm by PCS. For (90)Y-labelled Sb(2)S(3) and Sn colloid, a comparison of TEM and PCS indicates that these techniques found significantly different mean diameters. TEM has an excellent resol...ution necessary for radiocolloid particle-sizing analysis, and it is a desirable size-measuring technique because it is more reliable than PCS.
Кључне речи:
(90)Y / colloids / particle size / radiolabellingИзвор:
Journal of Microscopy, Oxford, 2008, 232, 3, 601-604Финансирање / пројекти:
- Истраживање механизма интеракција биолошки активних једињења са биомолекулима (RS-MESTD-MPN2006-2010-142051)
DOI: 10.1111/j.1365-2818.2008.02124.x
ISSN: 0022-2720
PubMed: 19094046
WoS: 000261253200032
Scopus: 2-s2.0-57449089169
Колекције
Институција/група
VinčaTY - JOUR AU - Janković, Drina AU - Maksin, Tatjana N. AU - Đokić, Divna Đ. AU - Milonjić, Slobodan K. AU - Nikolić, Nadežda S. AU - Mirković, Marija D. AU - Vranješ-Đurić, Sanja PY - 2008 UR - https://vinar.vin.bg.ac.rs/handle/123456789/3578 AB - Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for diagnosis and therapeutic purposes in nuclear medicine. Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle-size distribution of (90)Y- and (99m)Tc-labelled antimony trisulfide (Sb(2)S(3)) and tin colloids (Sn-colloid). (90)Y-Sb(2)S(3) and (99m)Tc-Sb(2)S(3) were found to have a diameter of 28.92 +/- 0.14 and 35.61 +/- 0.11 nm, respectively, by PCS. By TEM, (90)Y-Sb(2)S(3) particles were measured to be 14.33 +/- 0.09 nm. (90)Y-labelled Sn colloid were found to exist with a d(v(max1)) of 805 nm and a d(v(max2)) of 2590 nm, by PCS, whereas (99m)Tc-Sn colloid was shown to have more than 80% of radioactive particles of approximately 910 nm by PCS. For (90)Y-labelled Sb(2)S(3) and Sn colloid, a comparison of TEM and PCS indicates that these techniques found significantly different mean diameters. TEM has an excellent resolution necessary for radiocolloid particle-sizing analysis, and it is a desirable size-measuring technique because it is more reliable than PCS. T2 - Journal of Microscopy, Oxford T1 - Particle size analysis: (90)Y and (99m)Tc-labelled colloids VL - 232 IS - 3 SP - 601 EP - 604 DO - 10.1111/j.1365-2818.2008.02124.x ER -
@article{ author = "Janković, Drina and Maksin, Tatjana N. and Đokić, Divna Đ. and Milonjić, Slobodan K. and Nikolić, Nadežda S. and Mirković, Marija D. and Vranješ-Đurić, Sanja", year = "2008", abstract = "Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for diagnosis and therapeutic purposes in nuclear medicine. Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle-size distribution of (90)Y- and (99m)Tc-labelled antimony trisulfide (Sb(2)S(3)) and tin colloids (Sn-colloid). (90)Y-Sb(2)S(3) and (99m)Tc-Sb(2)S(3) were found to have a diameter of 28.92 +/- 0.14 and 35.61 +/- 0.11 nm, respectively, by PCS. By TEM, (90)Y-Sb(2)S(3) particles were measured to be 14.33 +/- 0.09 nm. (90)Y-labelled Sn colloid were found to exist with a d(v(max1)) of 805 nm and a d(v(max2)) of 2590 nm, by PCS, whereas (99m)Tc-Sn colloid was shown to have more than 80% of radioactive particles of approximately 910 nm by PCS. For (90)Y-labelled Sb(2)S(3) and Sn colloid, a comparison of TEM and PCS indicates that these techniques found significantly different mean diameters. TEM has an excellent resolution necessary for radiocolloid particle-sizing analysis, and it is a desirable size-measuring technique because it is more reliable than PCS.", journal = "Journal of Microscopy, Oxford", title = "Particle size analysis: (90)Y and (99m)Tc-labelled colloids", volume = "232", number = "3", pages = "601-604", doi = "10.1111/j.1365-2818.2008.02124.x" }
Janković, D., Maksin, T. N., Đokić, D. Đ., Milonjić, S. K., Nikolić, N. S., Mirković, M. D.,& Vranješ-Đurić, S.. (2008). Particle size analysis: (90)Y and (99m)Tc-labelled colloids. in Journal of Microscopy, Oxford, 232(3), 601-604. https://doi.org/10.1111/j.1365-2818.2008.02124.x
Janković D, Maksin TN, Đokić DĐ, Milonjić SK, Nikolić NS, Mirković MD, Vranješ-Đurić S. Particle size analysis: (90)Y and (99m)Tc-labelled colloids. in Journal of Microscopy, Oxford. 2008;232(3):601-604. doi:10.1111/j.1365-2818.2008.02124.x .
Janković, Drina, Maksin, Tatjana N., Đokić, Divna Đ., Milonjić, Slobodan K., Nikolić, Nadežda S., Mirković, Marija D., Vranješ-Đurić, Sanja, "Particle size analysis: (90)Y and (99m)Tc-labelled colloids" in Journal of Microscopy, Oxford, 232, no. 3 (2008):601-604, https://doi.org/10.1111/j.1365-2818.2008.02124.x . .