VinaR - Repository of the Vinča Nuclear Institute
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   Vinar
  • Vinča
  • WoS Import
  • View Item
  •   Vinar
  • Vinča
  • WoS Import
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease

Thumbnail
2007
3415.pdf (267.7Kb)
Authors
Stanković, Aleksandra
Stanković, Sanja
Jovanovic-Markovic, Zagorka
Živković, Maja
Đurić, Tamara
Glišić, Sanja (I)
Alavantić, Dragan
Article
Metadata
Show full item record
Abstract
The plasma concentration of apoB has recently been reported to be the best lipid predictor of coronary heart disease. The possible associations of genetic markers in the apolipoprotein B gene (Xbal, EcoRI, MspI, Ins/Del, and 4311 A/G polymorphisms) were evaluated in patients with ischemic cerebrovascular disease (ICVD) and controls of equivalent BMI. The odds ratio for ICVD in the X+X+ genotype was 2.22, 95% CI 1.24-3.96 (P LT 0.05), while that for ICVD in the Ins/Ins genotype was 2.82, 95% CI 1.57-5.06 (P LT 0.05). The patients had significantly higher frequency of the 4311 A allele compared to the controls (P LT 0.01). Our results support the assumption that apoB gene polymorphisms may contribute to the extent of cerebrovascular disease risk.
Keywords:
ApoB / ischemic cerebrovascular disease / gene / polymorphism / human population / Serbia
Source:
Archives of biological sciences, 2007, 59, 4, 303-309
Funding / projects:
  • Genetska epidemiologija i farmakogenomika vaskularnih oboljenja (RS-145023)

DOI: 10.2298/ABS0704303S

ISSN: 0354-4664

WoS: 000254920100008

[ Google Scholar ]
4
URI
https://vinar.vin.bg.ac.rs/handle/123456789/3419
Collections
  • WoS Import
Institution/Community
Vinča
TY  - JOUR
AU  - Stanković, Aleksandra
AU  - Stanković, Sanja
AU  - Jovanovic-Markovic, Zagorka
AU  - Živković, Maja
AU  - Đurić, Tamara
AU  - Glišić, Sanja (I)
AU  - Alavantić, Dragan
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3419
AB  - The plasma concentration of apoB has recently been reported to be the best lipid predictor of coronary heart disease. The possible associations of genetic markers in the apolipoprotein B gene (Xbal, EcoRI, MspI, Ins/Del, and 4311 A/G polymorphisms) were evaluated in patients with ischemic cerebrovascular disease (ICVD) and controls of equivalent BMI. The odds ratio for ICVD in the X+X+ genotype was 2.22, 95% CI 1.24-3.96 (P LT 0.05), while that for ICVD in the Ins/Ins genotype was 2.82, 95% CI 1.57-5.06 (P LT 0.05). The patients had significantly higher frequency of the 4311 A allele compared to the controls (P LT 0.01). Our results support the assumption that apoB gene polymorphisms may contribute to the extent of cerebrovascular disease risk.
T2  - Archives of biological sciences
T1  - Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease
VL  - 59
IS  - 4
SP  - 303
EP  - 309
DO  - 10.2298/ABS0704303S
ER  - 
@article{
author = "Stanković, Aleksandra and Stanković, Sanja and Jovanovic-Markovic, Zagorka and Živković, Maja and Đurić, Tamara and Glišić, Sanja (I) and Alavantić, Dragan",
year = "2007",
abstract = "The plasma concentration of apoB has recently been reported to be the best lipid predictor of coronary heart disease. The possible associations of genetic markers in the apolipoprotein B gene (Xbal, EcoRI, MspI, Ins/Del, and 4311 A/G polymorphisms) were evaluated in patients with ischemic cerebrovascular disease (ICVD) and controls of equivalent BMI. The odds ratio for ICVD in the X+X+ genotype was 2.22, 95% CI 1.24-3.96 (P LT 0.05), while that for ICVD in the Ins/Ins genotype was 2.82, 95% CI 1.57-5.06 (P LT 0.05). The patients had significantly higher frequency of the 4311 A allele compared to the controls (P LT 0.01). Our results support the assumption that apoB gene polymorphisms may contribute to the extent of cerebrovascular disease risk.",
journal = "Archives of biological sciences",
title = "Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease",
volume = "59",
number = "4",
pages = "303-309",
doi = "10.2298/ABS0704303S"
}
Stanković, A., Stanković, S., Jovanovic-Markovic, Z., Živković, M., Đurić, T., Glišić, S. (.,& Alavantić, D.. (2007). Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease. in Archives of biological sciences, 59(4), 303-309.
https://doi.org/10.2298/ABS0704303S
Stanković A, Stanković S, Jovanovic-Markovic Z, Živković M, Đurić T, Glišić S(, Alavantić D. Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease. in Archives of biological sciences. 2007;59(4):303-309.
doi:10.2298/ABS0704303S .
Stanković, Aleksandra, Stanković, Sanja, Jovanovic-Markovic, Zagorka, Živković, Maja, Đurić, Tamara, Glišić, Sanja (I), Alavantić, Dragan, "Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease" in Archives of biological sciences, 59, no. 4 (2007):303-309,
https://doi.org/10.2298/ABS0704303S . .

DSpace software copyright © 2002-2015  DuraSpace
About the VinaR Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About the VinaR Repository | Send Feedback

OpenAIRERCUB