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Toward novel HIV-1 integrase binding inhibitors: Molecular modeling, synthesis, and biological studies

dc.creatorMugnaini, Claudia
dc.creatorRajamaki, Suvi
dc.creatorTintori, Cristina
dc.creatorCorelli, Federico
dc.creatorMassa, Silivio
dc.creatorWitvrouw, Myriam
dc.creatorDebyser, Zeger
dc.creatorVeljković, Veljko
dc.creatorBotta, Maurizio
dc.date.accessioned2018-03-01T20:12:52Z
dc.date.available2018-03-01T20:12:52Z
dc.date.issued2007
dc.identifier.issn0960-894X
dc.identifier.urihttps://vinar.vin.bg.ac.rs/handle/123456789/3297
dc.description.abstractThe identification of a novel hit compound as integrase binding inhibitor has been accomplished by means of virtual screening techniques. A small family of structurally related molecules has been synthesized and biologically evaluated with one of the compounds showing an IC50 = 12 mu M (C) 2007 Elsevier Ltd. All rights reserved.en
dc.relationEuropean TRIoH Consortium [LSHB-2003-503480]
dc.rightsrestrictedAccessen
dc.sourceBioorganic and Medicinal Chemistry Lettersen
dc.subjectHIV-1en
dc.subjectintegrase inhibitorsen
dc.titleToward novel HIV-1 integrase binding inhibitors: Molecular modeling, synthesis, and biological studiesen
dc.typearticleen
dc.rights.licenseARR
dcterms.abstractРајамаки, Суви; Тинтори, Цристина; Цорелли, Федерицо; Масса, Силивио; Wитвроуw, Мyриам; Дебyсер, Зегер; Ботта, Мауризио; Мугнаини, Цлаудиа; Вељковић Вељко;
dc.citation.volume17
dc.citation.issue19
dc.citation.spage5370
dc.citation.epage5373
dc.identifier.wos000250041400016
dc.identifier.doi10.1016/j.bmcl.2007.08.005
dc.citation.rankM22
dc.identifier.pmid17716893
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-34548592004


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