Show simple item record

dc.creatorGavrilović, Ljubica
dc.creatorSpasojević, Nataša
dc.creatorDronjak, Slađana
dc.date.accessioned2018-03-01T20:09:05Z
dc.date.available2018-03-01T20:09:05Z
dc.date.issued2009
dc.identifier.issn1566-0702
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/3252
dc.description.abstractIn this study we investigated the changes in norepinephrine biosynthetic enzymes tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH) and phenylethanolamine N-methyltransferase (PNMT) gene expression in the stellate ganglia of naive controls and long-term socially isolated (12 weeks) adult rats and the response of these animals to additional immobilization stress. Psychosocial stress produced a significant increase of both TH mRNA and DBH mRNA levels in stellate ganglia. Additional immobilization of long-term psychosocially stressed rats expressed no effect on gene expression of these enzymes. The results presented here suggest that psychosocial stress-induced increase in gene expression of norepinephrine biosynthetic enzymes in stellate ganglia may be connected to the increased risk of cardiovascular disease. (C) 2009 Elsevier B.V. All rights reserved.en
dc.relationMinistry of Science and Technological Development of the Republic of Serbia [143044B]
dc.rightsrestrictedAccessen
dc.sourceAutonomic Neuroscience: Basic and Clinicalen
dc.subjectStellate gangliaen
dc.subjectPsychosocial stressen
dc.subjectNorepinephrineen
dc.subjectGene expressionen
dc.titlePsychosocial stress-related changes in gene expression of norepinephrine biosynthetic enzymes in stellate ganglia of adult ratsen
dc.typearticleen
dcterms.abstractГавриловић Љубица; Спасојевић Наташа; Дроњак Слађана;
dc.citation.volume150
dc.citation.issue1-2
dc.citation.spage144
dc.citation.epage146
dc.identifier.wos000270472800022
dc.identifier.doi10.1016/j.autneu.2009.05.242
dc.citation.rankM23
dc.identifier.pmid19482560
dc.identifier.scopus2-s2.0-69449097215


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record