Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. (c) 2007 Elsevier Ltd. All rights reserved.
Кључне речи:
flavonoids / in silico screening / anti-HIV compounds
Извор:
Bioorganic and Medicinal Chemistry Letters, 2007, 17, 5, 1226-1232
Финансирање / пројекти:
European Commission [TRIoH integrated project, Contract No. LSHB-CT-2003-50348]
TY - JOUR
AU - Veljković, Veljko
AU - Mouscadet, Jean-Francois
AU - Veljković, Nevena V.
AU - Glišić, Sanja
AU - Debyser, Zeger
PY - 2007
UR - https://vinar.vin.bg.ac.rs/handle/123456789/3166
AB - Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. (c) 2007 Elsevier Ltd. All rights reserved.
T2 - Bioorganic and Medicinal Chemistry Letters
T1 - Simple criterion for selection of flavonoid compounds with anti-HIV activity
VL - 17
IS - 5
SP - 1226
EP - 1232
DO - 10.1016/j.bmcl.2006.12.029
ER -
@article{
author = "Veljković, Veljko and Mouscadet, Jean-Francois and Veljković, Nevena V. and Glišić, Sanja and Debyser, Zeger",
year = "2007",
abstract = "Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity. (c) 2007 Elsevier Ltd. All rights reserved.",
journal = "Bioorganic and Medicinal Chemistry Letters",
title = "Simple criterion for selection of flavonoid compounds with anti-HIV activity",
volume = "17",
number = "5",
pages = "1226-1232",
doi = "10.1016/j.bmcl.2006.12.029"
}
Veljković, V., Mouscadet, J., Veljković, N. V., Glišić, S.,& Debyser, Z.. (2007). Simple criterion for selection of flavonoid compounds with anti-HIV activity. in Bioorganic and Medicinal Chemistry Letters, 17(5), 1226-1232.
https://doi.org/10.1016/j.bmcl.2006.12.029
Veljković V, Mouscadet J, Veljković NV, Glišić S, Debyser Z. Simple criterion for selection of flavonoid compounds with anti-HIV activity. in Bioorganic and Medicinal Chemistry Letters. 2007;17(5):1226-1232.
doi:10.1016/j.bmcl.2006.12.029 .
Veljković, Veljko, Mouscadet, Jean-Francois, Veljković, Nevena V., Glišić, Sanja, Debyser, Zeger, "Simple criterion for selection of flavonoid compounds with anti-HIV activity" in Bioorganic and Medicinal Chemistry Letters, 17, no. 5 (2007):1226-1232,
https://doi.org/10.1016/j.bmcl.2006.12.029 . .
