Factorial design in isocratic high-performance liquid chromatography of phenolic compounds
Апстракт
A multifactor optimization strategy was utilized to predict the isocratic HPLC separation of nine phenols. The retention behavior was studied as a function of changing eluent (methanol - acetic acid) composition. The predicted and measured retentions; are in rather good agreement. To locate the optimum in the factor space, the normalized resolution product criterion was applied. In virtually every case, the resolution is limited by the separation of the 2-chlorophenol and 2,4-dinitrophenol pair.
Кључне речи:
factorial design / phenols / HPLC / resolution product / isocraticИзвор:
Journal of the Serbian Chemical Society, 2002, 67, 11, 745-751
DOI: 10.2298/JSC0211745O
ISSN: 0352-5139
WoS: 000179956900005
Scopus: 2-s2.0-0036982845
Колекције
Институција/група
VinčaTY - JOUR AU - Onjia, Antonije E. AU - Vasiljevic, T AU - Čokeša, Đuro AU - Laušević, Mila D. PY - 2002 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2593 AB - A multifactor optimization strategy was utilized to predict the isocratic HPLC separation of nine phenols. The retention behavior was studied as a function of changing eluent (methanol - acetic acid) composition. The predicted and measured retentions; are in rather good agreement. To locate the optimum in the factor space, the normalized resolution product criterion was applied. In virtually every case, the resolution is limited by the separation of the 2-chlorophenol and 2,4-dinitrophenol pair. T2 - Journal of the Serbian Chemical Society T1 - Factorial design in isocratic high-performance liquid chromatography of phenolic compounds VL - 67 IS - 11 SP - 745 EP - 751 DO - 10.2298/JSC0211745O ER -
@article{ author = "Onjia, Antonije E. and Vasiljevic, T and Čokeša, Đuro and Laušević, Mila D.", year = "2002", abstract = "A multifactor optimization strategy was utilized to predict the isocratic HPLC separation of nine phenols. The retention behavior was studied as a function of changing eluent (methanol - acetic acid) composition. The predicted and measured retentions; are in rather good agreement. To locate the optimum in the factor space, the normalized resolution product criterion was applied. In virtually every case, the resolution is limited by the separation of the 2-chlorophenol and 2,4-dinitrophenol pair.", journal = "Journal of the Serbian Chemical Society", title = "Factorial design in isocratic high-performance liquid chromatography of phenolic compounds", volume = "67", number = "11", pages = "745-751", doi = "10.2298/JSC0211745O" }
Onjia, A. E., Vasiljevic, T., Čokeša, Đ.,& Laušević, M. D.. (2002). Factorial design in isocratic high-performance liquid chromatography of phenolic compounds. in Journal of the Serbian Chemical Society, 67(11), 745-751. https://doi.org/10.2298/JSC0211745O
Onjia AE, Vasiljevic T, Čokeša Đ, Laušević MD. Factorial design in isocratic high-performance liquid chromatography of phenolic compounds. in Journal of the Serbian Chemical Society. 2002;67(11):745-751. doi:10.2298/JSC0211745O .
Onjia, Antonije E., Vasiljevic, T, Čokeša, Đuro, Laušević, Mila D., "Factorial design in isocratic high-performance liquid chromatography of phenolic compounds" in Journal of the Serbian Chemical Society, 67, no. 11 (2002):745-751, https://doi.org/10.2298/JSC0211745O . .