Show simple item record

dc.creatorStanković, Aleksandra
dc.creatorIlic, N
dc.creatorŽunić, Zora S.
dc.creatorGlišić, Sanja (I)
dc.creatorAlavantić, Dragan
dc.date.accessioned2018-03-01T18:47:40Z
dc.date.available2018-03-01T18:47:40Z
dc.date.issued1999
dc.identifier.issn0354-3447 (print)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/2307
dc.description.abstractWe have determined frequencies of alleles and genotypes at angiotensinl-converting enzyme (ACE) locus by polymerase chain reaction (PCR) in the healthy population of Belgrade. We also studied the association of this polymorphism with blood pressure (BP) level. When we controlled the other cardiovascular risk factors, moderate association of borderline significance between DD genotype and hypertension (HT) (OR = 1.88, 95% CI, 1.00 to 3.56, P = 0.050) was noted. We concluded that DD genotype of ACE locus predicts HT independently of other factors. No significant effect of the ACE gene polymorphism on systolic and diastolic BP is found by MANCOVA. We hypothesize that ACE is not involved as much in determining the BP values as it is involved in modulation of blood-pressure genes.en
dc.rightsrestrictedAccessen
dc.sourceJugoslovenska Medicinska Biohemijaen
dc.subjecthypertensionen
dc.subjectACEen
dc.subjectinsertion/deletion polymorphismen
dc.subjectpolymerase chain reactionen
dc.titleAssociation of the insertion/deletion polymorphism at the angiotensin I-converting enzyme locus with arterial blood pressure: Population-based studyen
dc.typearticleen
dcterms.abstractИлиц, Н; Зуниц, З; Станковић Aлександра; Глишић Сања; Aлавантић Драган;
dc.citation.volume18
dc.citation.issue4
dc.citation.spage141
dc.citation.epage147
dc.identifier.wos000084404300002
dc.citation.rankM23


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record