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Effects of progesterone and estradiol benzoate on superoxide dismutase activity in the brain of male rats
dc.creator | Pajović, Snežana B. | |
dc.creator | Saičić, Zorica S. | |
dc.creator | Spasić, Mihajlo | |
dc.creator | Petrović, Vojislav M. | |
dc.creator | Martinović, Jelena | |
dc.date.accessioned | 2018-03-01T18:11:45Z | |
dc.date.available | 2018-03-01T18:11:45Z | |
dc.date.issued | 1996 | |
dc.identifier.issn | 0014-4754 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/1969 | |
dc.description.abstract | The activities of mitochondrial, manganese-containing superoxide dismutase (MnSOD) and cytoplasmic, copper-zinc-containing superoxide dismutase (CuZnSOD) were measured in subcellular fractions of whole brain homogenates prepared from intact and gonadectomized (GDX) male rats, untreated or treated subcutaneously (sc) with a single dose of 2 mg progesterone (P) and/or 5 mu g estradiol benzoate (EB). Neither MnSOD nor CuZnSOD was affected by the removal of the testes. Similarly, CuZnSOD activity was steady following systemic administration of P and/or EB to intact and GDX animals 2 h or 24 h prior to sacrifice. On the other hand, both P and EB suppressed MnSOD in the brain of either intact or GDX rats. These results suggest involvement of P and EB in the control of MnSOD activity in the brain of male rats. | en |
dc.rights | restrictedAccess | en |
dc.source | Experientia | en |
dc.subject | superoxide dismutase | en |
dc.subject | brain | en |
dc.subject | progesterone | en |
dc.subject | estradiol | en |
dc.subject | rats | en |
dc.title | Effects of progesterone and estradiol benzoate on superoxide dismutase activity in the brain of male rats | en |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Пајовиц, С; Спасиц, МБ; Петровиц, ВМ; Мартиновић Јелена; Саициц, ЗС; | |
dc.citation.volume | 52 | |
dc.citation.issue | 3 | |
dc.citation.spage | 221 | |
dc.citation.epage | 224 | |
dc.identifier.wos | A1996UC55500004 | |
dc.identifier.doi | 10.1007/BF01920710 | |
dc.identifier.pmid | 8631389 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-0029664529 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_vinar_1969 |
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