The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
TY - JOUR
AU - Mitrović, Marko B.
AU - Ciraj-Bjelac, Olivera
AU - Oreščanin-Dušić, Zorana S.
AU - Blagojević, Duško P.
AU - Nikolić-Kokić, Aleksandra L.
AU - Tatalović, Nikola R.
AU - Krstić, Nikola E.
AU - Lazarević-Macanović, Mirjana V.
PY - 2017
UR - https://vinar.vin.bg.ac.rs/handle/123456789/1934
AB - The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
T2 - Nuclear technology and radiation protection
T1 - Influence of Radiation Dose in Computed Tomography on Antioxidant Enzyme Activity in Rabbit Erythrocytes
VL - 32
IS - 4
SP - 342
EP - 349
DO - 10.2298/NTRP1704342M
ER -
@article{
author = "Mitrović, Marko B. and Ciraj-Bjelac, Olivera and Oreščanin-Dušić, Zorana S. and Blagojević, Duško P. and Nikolić-Kokić, Aleksandra L. and Tatalović, Nikola R. and Krstić, Nikola E. and Lazarević-Macanović, Mirjana V.",
year = "2017",
abstract = "The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.",
journal = "Nuclear technology and radiation protection",
title = "Influence of Radiation Dose in Computed Tomography on Antioxidant Enzyme Activity in Rabbit Erythrocytes",
volume = "32",
number = "4",
pages = "342-349",
doi = "10.2298/NTRP1704342M"
}
Mitrović, M. B., Ciraj-Bjelac, O., Oreščanin-Dušić, Z. S., Blagojević, D. P., Nikolić-Kokić, A. L., Tatalović, N. R., Krstić, N. E.,& Lazarević-Macanović, M. V.. (2017). Influence of Radiation Dose in Computed Tomography on Antioxidant Enzyme Activity in Rabbit Erythrocytes. in Nuclear technology and radiation protection, 32(4), 342-349.
https://doi.org/10.2298/NTRP1704342M
Mitrović MB, Ciraj-Bjelac O, Oreščanin-Dušić ZS, Blagojević DP, Nikolić-Kokić AL, Tatalović NR, Krstić NE, Lazarević-Macanović MV. Influence of Radiation Dose in Computed Tomography on Antioxidant Enzyme Activity in Rabbit Erythrocytes. in Nuclear technology and radiation protection. 2017;32(4):342-349.
doi:10.2298/NTRP1704342M .
Mitrović, Marko B., Ciraj-Bjelac, Olivera, Oreščanin-Dušić, Zorana S., Blagojević, Duško P., Nikolić-Kokić, Aleksandra L., Tatalović, Nikola R., Krstić, Nikola E., Lazarević-Macanović, Mirjana V., "Influence of Radiation Dose in Computed Tomography on Antioxidant Enzyme Activity in Rabbit Erythrocytes" in Nuclear technology and radiation protection, 32, no. 4 (2017):342-349,
https://doi.org/10.2298/NTRP1704342M . .
