Clinicopathological characteristics and survival in Serbian patients with renal cell carcinoma: a retrospective analysis
Само за регистроване кориснике
2017
Аутори
Pavlović, IvanPejić, Snežana
Glumac, Sofija
Todorović, Ana
Stojiljković, Vesna
Popović, Nataša M.
Gavrilović, Ljubica
Pajović, Snežana B.
Radojević-Škodrić, Sanja
Džamić, Zoran
Basta-Jovanović, Gordana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Purpose: Indications of kidney cancer outcome in lower-income countries are based on an incidence/mortality ratio due to lack of survival information. This study was conducted to provide outcome data in Serbian patients with renal cell carcinoma (RCC) and to identify prognostic factors that could affect their overall survival (OS). Methods: This retrospective study included 185 patients who underwent nephrectomy. We assessed certain clinicopathological data including age, gender, tumor size, grade, stage and histological subtypes for their possible impact on OS. Results: The 5-year OS was 63.2%. Significant association was found between OS and age (log-rank 12.455, p=0.006), tumor size (log-rank 26.425, p=0.000), grade (log-rank 13.249, p=0.000) and stage (log-rank 43.235, p=0.000). Univariate analysis indicated size (p=0.000), grade (p=0.001) and stage (p=0.000) as prognostic factors for OS. In multivariate analysis, grade (p=0.014) and stage (p=0.000) remained significant predictors ...of OS. Conclusion: Tumor grade and stage were identified as independent prognostic factors of OS survival in Serbian patients with RCC.
Кључне речи:
kidney cancer / overall survival / prognostic factors / renal cell carcinoma / retrospective analysisИзвор:
Journal of BUON, 2017, 22, 6, 1434-1440Финансирање / пројекти:
- Ћелијске и молекулске основе малигних и кардиоваскуларних обољења-клиничке импликације (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41027)
ISSN: 1107-0625; 2241-6293
PubMed: 29332335
WoS: 000417154000011
Scopus: 2-s2.0-85045626414
Институција/група
VinčaTY - JOUR AU - Pavlović, Ivan AU - Pejić, Snežana AU - Glumac, Sofija AU - Todorović, Ana AU - Stojiljković, Vesna AU - Popović, Nataša M. AU - Gavrilović, Ljubica AU - Pajović, Snežana B. AU - Radojević-Škodrić, Sanja AU - Džamić, Zoran AU - Basta-Jovanović, Gordana PY - 2017 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1857 AB - Purpose: Indications of kidney cancer outcome in lower-income countries are based on an incidence/mortality ratio due to lack of survival information. This study was conducted to provide outcome data in Serbian patients with renal cell carcinoma (RCC) and to identify prognostic factors that could affect their overall survival (OS). Methods: This retrospective study included 185 patients who underwent nephrectomy. We assessed certain clinicopathological data including age, gender, tumor size, grade, stage and histological subtypes for their possible impact on OS. Results: The 5-year OS was 63.2%. Significant association was found between OS and age (log-rank 12.455, p=0.006), tumor size (log-rank 26.425, p=0.000), grade (log-rank 13.249, p=0.000) and stage (log-rank 43.235, p=0.000). Univariate analysis indicated size (p=0.000), grade (p=0.001) and stage (p=0.000) as prognostic factors for OS. In multivariate analysis, grade (p=0.014) and stage (p=0.000) remained significant predictors of OS. Conclusion: Tumor grade and stage were identified as independent prognostic factors of OS survival in Serbian patients with RCC. T2 - Journal of BUON T1 - Clinicopathological characteristics and survival in Serbian patients with renal cell carcinoma: a retrospective analysis VL - 22 IS - 6 SP - 1434 EP - 1440 UR - https://hdl.handle.net/21.15107/rcub_vinar_1857 ER -
@article{ author = "Pavlović, Ivan and Pejić, Snežana and Glumac, Sofija and Todorović, Ana and Stojiljković, Vesna and Popović, Nataša M. and Gavrilović, Ljubica and Pajović, Snežana B. and Radojević-Škodrić, Sanja and Džamić, Zoran and Basta-Jovanović, Gordana", year = "2017", abstract = "Purpose: Indications of kidney cancer outcome in lower-income countries are based on an incidence/mortality ratio due to lack of survival information. This study was conducted to provide outcome data in Serbian patients with renal cell carcinoma (RCC) and to identify prognostic factors that could affect their overall survival (OS). Methods: This retrospective study included 185 patients who underwent nephrectomy. We assessed certain clinicopathological data including age, gender, tumor size, grade, stage and histological subtypes for their possible impact on OS. Results: The 5-year OS was 63.2%. Significant association was found between OS and age (log-rank 12.455, p=0.006), tumor size (log-rank 26.425, p=0.000), grade (log-rank 13.249, p=0.000) and stage (log-rank 43.235, p=0.000). Univariate analysis indicated size (p=0.000), grade (p=0.001) and stage (p=0.000) as prognostic factors for OS. In multivariate analysis, grade (p=0.014) and stage (p=0.000) remained significant predictors of OS. Conclusion: Tumor grade and stage were identified as independent prognostic factors of OS survival in Serbian patients with RCC.", journal = "Journal of BUON", title = "Clinicopathological characteristics and survival in Serbian patients with renal cell carcinoma: a retrospective analysis", volume = "22", number = "6", pages = "1434-1440", url = "https://hdl.handle.net/21.15107/rcub_vinar_1857" }
Pavlović, I., Pejić, S., Glumac, S., Todorović, A., Stojiljković, V., Popović, N. M., Gavrilović, L., Pajović, S. B., Radojević-Škodrić, S., Džamić, Z.,& Basta-Jovanović, G.. (2017). Clinicopathological characteristics and survival in Serbian patients with renal cell carcinoma: a retrospective analysis. in Journal of BUON, 22(6), 1434-1440. https://hdl.handle.net/21.15107/rcub_vinar_1857
Pavlović I, Pejić S, Glumac S, Todorović A, Stojiljković V, Popović NM, Gavrilović L, Pajović SB, Radojević-Škodrić S, Džamić Z, Basta-Jovanović G. Clinicopathological characteristics and survival in Serbian patients with renal cell carcinoma: a retrospective analysis. in Journal of BUON. 2017;22(6):1434-1440. https://hdl.handle.net/21.15107/rcub_vinar_1857 .
Pavlović, Ivan, Pejić, Snežana, Glumac, Sofija, Todorović, Ana, Stojiljković, Vesna, Popović, Nataša M., Gavrilović, Ljubica, Pajović, Snežana B., Radojević-Škodrić, Sanja, Džamić, Zoran, Basta-Jovanović, Gordana, "Clinicopathological characteristics and survival in Serbian patients with renal cell carcinoma: a retrospective analysis" in Journal of BUON, 22, no. 6 (2017):1434-1440, https://hdl.handle.net/21.15107/rcub_vinar_1857 .