Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene impr...oves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating.
TY - JOUR
AU - Marković, Zoran M.
AU - Kepić, Dejan P.
AU - Matijasevic, D. M.
AU - Pavlović, Vladimir B.
AU - Jovanović, Svetlana P.
AU - Stankovic, N. K.
AU - Milivojević, Dušan
AU - Špitalsky, Zdenko
AU - Holclajtner-Antunović, Ivanka D.
AU - Bajuk-Bogdanović, Danica V.
AU - Niksic, M. P.
AU - Todorović-Marković, Biljana
PY - 2017
UR - https://vinar.vin.bg.ac.rs/handle/123456789/1650
AB - Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene improves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating.
T2 - RSC Advances
T1 - Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids
VL - 7
IS - 57
SP - 36081
EP - 36092
DO - 10.1039/c7ra05027e
ER -
@article{
author = "Marković, Zoran M. and Kepić, Dejan P. and Matijasevic, D. M. and Pavlović, Vladimir B. and Jovanović, Svetlana P. and Stankovic, N. K. and Milivojević, Dušan and Špitalsky, Zdenko and Holclajtner-Antunović, Ivanka D. and Bajuk-Bogdanović, Danica V. and Niksic, M. P. and Todorović-Marković, Biljana",
year = "2017",
abstract = "Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene improves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating.",
journal = "RSC Advances",
title = "Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids",
volume = "7",
number = "57",
pages = "36081-36092",
doi = "10.1039/c7ra05027e"
}
Marković, Z. M., Kepić, D. P., Matijasevic, D. M., Pavlović, V. B., Jovanović, S. P., Stankovic, N. K., Milivojević, D., Špitalsky, Z., Holclajtner-Antunović, I. D., Bajuk-Bogdanović, D. V., Niksic, M. P.,& Todorović-Marković, B.. (2017). Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids. in RSC Advances, 7(57), 36081-36092.
https://doi.org/10.1039/c7ra05027e
