New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.
TY - JOUR
AU - Malagurski, Ivana
AU - Levic, Steva
AU - Pantic, Milena
AU - Matijasevic, Danka
AU - Mitrić, Miodrag
AU - Pavlović, Vladimir B.
AU - Dimitrijević-Branković, Suzana I.
PY - 2017
UR - https://vinar.vin.bg.ac.rs/handle/123456789/1508
AB - New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.
T2 - Carbohydrate Polymers
T1 - Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites
VL - 165
SP - 313
EP - 321
DO - 10.1016/j.carbpol.2017.02.064
ER -
@article{
author = "Malagurski, Ivana and Levic, Steva and Pantic, Milena and Matijasevic, Danka and Mitrić, Miodrag and Pavlović, Vladimir B. and Dimitrijević-Branković, Suzana I.",
year = "2017",
abstract = "New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.",
journal = "Carbohydrate Polymers",
title = "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites",
volume = "165",
pages = "313-321",
doi = "10.1016/j.carbpol.2017.02.064"
}
Malagurski, I., Levic, S., Pantic, M., Matijasevic, D., Mitrić, M., Pavlović, V. B.,& Dimitrijević-Branković, S. I.. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers, 165, 313-321.
https://doi.org/10.1016/j.carbpol.2017.02.064
Malagurski I, Levic S, Pantic M, Matijasevic D, Mitrić M, Pavlović VB, Dimitrijević-Branković SI. Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers. 2017;165:313-321.
doi:10.1016/j.carbpol.2017.02.064 .
Malagurski, Ivana, Levic, Steva, Pantic, Milena, Matijasevic, Danka, Mitrić, Miodrag, Pavlović, Vladimir B., Dimitrijević-Branković, Suzana I., "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites" in Carbohydrate Polymers, 165 (2017):313-321,
https://doi.org/10.1016/j.carbpol.2017.02.064 . .
