Application of Carbon-Based Nanocomposite Systems as Photosensitizers for Photodynamic Therapy
Autori
Petković, Marijana![](/themes/MirageVinar/images/orcid.png)
Stepić, Milutin
![](/themes/MirageVinar/images/orcid.png)
Popović, Iva
![](/themes/MirageVinar/images/orcid.png)
Algarra, Manuel
Dučić, Tanja
Abu el Rub, Anamarija
![](/themes/MirageVinar/images/orcid.png)
Ralić, Vanja
![](/themes/MirageVinar/images/orcid.png)
Korićanac, Lela
![](/themes/MirageVinar/images/orcid.png)
Žakula, Jelena
![](/themes/MirageVinar/images/orcid.png)
Filipović Tričković, Jelena
![](/themes/MirageVinar/images/orcid.png)
Valenta Šobot, Ana
![](/themes/MirageVinar/images/orcid.png)
Nešić, Maja D.
![](/themes/MirageVinar/images/orcid.png)
Konferencijski prilog (Objavljena verzija)
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Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Small, carbon-based nanoparticles, carbon dots (CDs), are investigated as photosensitizers (PSs) for photodynamic therapy of cancers. The results presented here show biochemical changes in cancer cells treated with surface-modified CDs, which are augmented by illumination, indicating a high potential of CDs as selective drug carriers and potent PSs. In addition, we will show that CDs produced from black carrot extract (biomass) can be exploited for image-guided therapy and be cytotoxic for cancer cells, thanks to their fluorescence properties. Finally, since biomass-fabricated CDs interact strongly with nucleic acids, they can be further developed for cell cycle sensing purposes.
Ključne reči:
Carbon dots / Photodynamic therapy / cancer / theranostic / biomassIzvor:
ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings, 2023, 61-66Izdavač:
- Institute for Information Technologies, University of Kragujevac
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200017 (Univerzitet u Beogradu, Institut za nuklearne nauke Vinča, Beograd-Vinča) (RS-MESTD-inst-2020-200017)
- Spanish Ministry of Science and Innovation (MCIN/AEI/10.13039/501100011033) [project PID2021-122613OB-I00]
- ALBA Synchrotron with the collaboration of ALBA staff [experiment No. 2022025758]
Kolekcije
Institucija/grupa
VinčaTY - CONF AU - Petković, Marijana AU - Stepić, Milutin AU - Popović, Iva AU - Algarra, Manuel AU - Dučić, Tanja AU - Abu el Rub, Anamarija AU - Ralić, Vanja AU - Korićanac, Lela AU - Žakula, Jelena AU - Filipović Tričković, Jelena AU - Valenta Šobot, Ana AU - Nešić, Maja D. PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/13568 AB - Small, carbon-based nanoparticles, carbon dots (CDs), are investigated as photosensitizers (PSs) for photodynamic therapy of cancers. The results presented here show biochemical changes in cancer cells treated with surface-modified CDs, which are augmented by illumination, indicating a high potential of CDs as selective drug carriers and potent PSs. In addition, we will show that CDs produced from black carrot extract (biomass) can be exploited for image-guided therapy and be cytotoxic for cancer cells, thanks to their fluorescence properties. Finally, since biomass-fabricated CDs interact strongly with nucleic acids, they can be further developed for cell cycle sensing purposes. PB - Institute for Information Technologies, University of Kragujevac C3 - ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings T1 - Application of Carbon-Based Nanocomposite Systems as Photosensitizers for Photodynamic Therapy SP - 61 EP - 66 DO - 10.46793/ICCBI23.061P ER -
@conference{ author = "Petković, Marijana and Stepić, Milutin and Popović, Iva and Algarra, Manuel and Dučić, Tanja and Abu el Rub, Anamarija and Ralić, Vanja and Korićanac, Lela and Žakula, Jelena and Filipović Tričković, Jelena and Valenta Šobot, Ana and Nešić, Maja D.", year = "2023", abstract = "Small, carbon-based nanoparticles, carbon dots (CDs), are investigated as photosensitizers (PSs) for photodynamic therapy of cancers. The results presented here show biochemical changes in cancer cells treated with surface-modified CDs, which are augmented by illumination, indicating a high potential of CDs as selective drug carriers and potent PSs. In addition, we will show that CDs produced from black carrot extract (biomass) can be exploited for image-guided therapy and be cytotoxic for cancer cells, thanks to their fluorescence properties. Finally, since biomass-fabricated CDs interact strongly with nucleic acids, they can be further developed for cell cycle sensing purposes.", publisher = "Institute for Information Technologies, University of Kragujevac", journal = "ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings", title = "Application of Carbon-Based Nanocomposite Systems as Photosensitizers for Photodynamic Therapy", pages = "61-66", doi = "10.46793/ICCBI23.061P" }
Petković, M., Stepić, M., Popović, I., Algarra, M., Dučić, T., Abu el Rub, A., Ralić, V., Korićanac, L., Žakula, J., Filipović Tričković, J., Valenta Šobot, A.,& Nešić, M. D.. (2023). Application of Carbon-Based Nanocomposite Systems as Photosensitizers for Photodynamic Therapy. in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings Institute for Information Technologies, University of Kragujevac., 61-66. https://doi.org/10.46793/ICCBI23.061P
Petković M, Stepić M, Popović I, Algarra M, Dučić T, Abu el Rub A, Ralić V, Korićanac L, Žakula J, Filipović Tričković J, Valenta Šobot A, Nešić MD. Application of Carbon-Based Nanocomposite Systems as Photosensitizers for Photodynamic Therapy. in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings. 2023;:61-66. doi:10.46793/ICCBI23.061P .
Petković, Marijana, Stepić, Milutin, Popović, Iva, Algarra, Manuel, Dučić, Tanja, Abu el Rub, Anamarija, Ralić, Vanja, Korićanac, Lela, Žakula, Jelena, Filipović Tričković, Jelena, Valenta Šobot, Ana, Nešić, Maja D., "Application of Carbon-Based Nanocomposite Systems as Photosensitizers for Photodynamic Therapy" in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings (2023):61-66, https://doi.org/10.46793/ICCBI23.061P . .