Biomedical Potential of mTOR Modulation by Nanoparticles
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Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses. Understanding the mechanisms and biological actions of nanoparticle-mediated mTOR modulation may help in developing safe and efficient nano therapeutics to fight human disease.
Source:Trends in Biotechnology, 2016, 34, 5, 349-353