Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine
Authors
Marković, Zoran M.
Budimir, Milica

Danko, Martin

Milivojević, Dušan

Kubat, Pavel

Zmejkoski, Danica

Pavlović, Vladimir B.

Mojsin, Marija

Stevanović, Milena J.

Todorović-Marković, Biljana

Article (Published version)
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Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, carbon quantum dots were prepared from o-phenylenediamine dissolved in toluene by a solvothermal route. Subsequently, the prepared carbon quantum dots were encapsulated into polyurethane films by a swelling–encapsulation–shrink method. Analyses of the results obtained by different characterization methods (AFM, TEM, EDS, FTIR, photoluminescence, and EPR) indicate the significant influence of the precursor on structural, chemical, and optical properties. Antibacterial and cytotoxicity tests showed that these dots did not have any antibacterial potential, because of the low extent of reactive oxygen species production, and showed low dark cytotoxicity. By investigating the cellular uptake, it was established that these dots penetrated the ...HeLa cells and could be used as probes for bioimaging.
Keywords:
antibacterial / bioimaging / carbon quantum dots / precursor / reactive oxygen speciesSource:
Beilstein Journal of Nanotechnology, 2023, 14, 1, 165-174Funding / projects:
- PHOTOGUN4MICROBES - Are photoactive nanoparticles salvation for global infectional treath? (RS-7741955)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200017 (University of Belgrade, Institute of Nuclear Sciences 'Vinča', Belgrade-Vinča) (RS-200017)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200042 (University of Belgrade, Institute of Molecular Genetics and Genetic Engineering) (RS-200042)
Institution/Community
VinčaTY - JOUR AU - Marković, Zoran M. AU - Budimir, Milica AU - Danko, Martin AU - Milivojević, Dušan AU - Kubat, Pavel AU - Zmejkoski, Danica AU - Pavlović, Vladimir B. AU - Mojsin, Marija AU - Stevanović, Milena J. AU - Todorović-Marković, Biljana PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/10632 AB - Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, carbon quantum dots were prepared from o-phenylenediamine dissolved in toluene by a solvothermal route. Subsequently, the prepared carbon quantum dots were encapsulated into polyurethane films by a swelling–encapsulation–shrink method. Analyses of the results obtained by different characterization methods (AFM, TEM, EDS, FTIR, photoluminescence, and EPR) indicate the significant influence of the precursor on structural, chemical, and optical properties. Antibacterial and cytotoxicity tests showed that these dots did not have any antibacterial potential, because of the low extent of reactive oxygen species production, and showed low dark cytotoxicity. By investigating the cellular uptake, it was established that these dots penetrated the HeLa cells and could be used as probes for bioimaging. T2 - Beilstein Journal of Nanotechnology T1 - Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine VL - 14 IS - 1 SP - 165 EP - 174 DO - 10.3762/bjnano.14.17 ER -
@article{ author = "Marković, Zoran M. and Budimir, Milica and Danko, Martin and Milivojević, Dušan and Kubat, Pavel and Zmejkoski, Danica and Pavlović, Vladimir B. and Mojsin, Marija and Stevanović, Milena J. and Todorović-Marković, Biljana", year = "2023", abstract = "Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, carbon quantum dots were prepared from o-phenylenediamine dissolved in toluene by a solvothermal route. Subsequently, the prepared carbon quantum dots were encapsulated into polyurethane films by a swelling–encapsulation–shrink method. Analyses of the results obtained by different characterization methods (AFM, TEM, EDS, FTIR, photoluminescence, and EPR) indicate the significant influence of the precursor on structural, chemical, and optical properties. Antibacterial and cytotoxicity tests showed that these dots did not have any antibacterial potential, because of the low extent of reactive oxygen species production, and showed low dark cytotoxicity. By investigating the cellular uptake, it was established that these dots penetrated the HeLa cells and could be used as probes for bioimaging.", journal = "Beilstein Journal of Nanotechnology", title = "Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine", volume = "14", number = "1", pages = "165-174", doi = "10.3762/bjnano.14.17" }
Marković, Z. M., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V. B., Mojsin, M., Stevanović, M. J.,& Todorović-Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174. https://doi.org/10.3762/bjnano.14.17
Marković ZM, Budimir M, Danko M, Milivojević D, Kubat P, Zmejkoski D, Pavlović VB, Mojsin M, Stevanović MJ, Todorović-Marković B. Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology. 2023;14(1):165-174. doi:10.3762/bjnano.14.17 .
Marković, Zoran M., Budimir, Milica, Danko, Martin, Milivojević, Dušan, Kubat, Pavel, Zmejkoski, Danica, Pavlović, Vladimir B., Mojsin, Marija, Stevanović, Milena J., Todorović-Marković, Biljana, "Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine" in Beilstein Journal of Nanotechnology, 14, no. 1 (2023):165-174, https://doi.org/10.3762/bjnano.14.17 . .