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dc.creatorBajić, Vladan P.
dc.creatorSudar, Emina
dc.creatorSpremo-Potparević, Biljana
dc.creatorŽivković, Lada
dc.creatorMilićević, Zorka T.
dc.creatorStanimirović, Julijana
dc.creatorBogdanović, Nikola
dc.creatorIsenović, Esma R.
dc.date.accessioned2018-03-01T16:50:49Z
dc.date.available2018-03-01T16:50:49Z
dc.date.issued2016
dc.identifier.issn1573-4129 (print)
dc.identifier.issn1875-676X (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/1039
dc.description.abstractAlzheimers disease (AD) is a complex and progressive neurodegenerative disorder, and represents the most common form of dementia. The number of people affected by AD is estimated to be doubled by the year of 2050, and more than 100 million people worldwide will be affected by this disease. Still, there is no reliable diagnostic test which would indicate pre-symptomatic conditions or an increased risk of developing AD. The only drugs approved by the FDA belong to the cholinesterase inhibitors (ChEI) group, such as donepezil, rivastigmine, galantamine and memantine that belongs to a class of drugs named receptor NMDA antagonists. Most mainstream pharmacotherapeutic approaches act by slowing the progression of the condition rather than to treat or prevent the cause of AD. In this review we are presenting literature data from recent research related to new avenues in the classical approach to prevention and treatment of AD.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173033/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173034/RS//
dc.rightsrestrictedAccessen
dc.sourceCurrent Pharmaceutical Analysisen
dc.subjectA betaen
dc.subjectAlzheimers diseaseen
dc.subjectcholinesterase inhibitorsen
dc.subjecthybridsen
dc.subjectmemantineen
dc.subjectneurodegenerationen
dc.titleTreatment of Alzheimers Disease: Classical Therapeutic Approachen
dc.typearticleen
dcterms.abstractСпремо-Потпаревиц, Биљана; Бајић Владан П.; Милиццивц, Зорка; Судар Емина; Богдановиц, Никола; Станимировић Јулијана; Зивковиц, Лада; Исеновић Есма;
dc.citation.volume12
dc.citation.issue2
dc.citation.spage82
dc.citation.epage90
dc.identifier.wos000374885700001
dc.identifier.doi10.2174/1573412911666150611184740
dc.citation.rankM23
dc.identifier.scopus2-s2.0-84961637983


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