Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
Authors
Magić, MarkoČolović, Božana M.

Vasilijić, Saša

Tadić, Nenad
Stojadinović, Stevan

Jokanović, Vukoman R.

Article (Published version)
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The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
Keywords:
implants / LDH assay / MTT assay / plasma electrolytic oxidation / TitaniumSource:
Journal of Applied Biomaterials & Functional Materials, 2021, 19Funding / projects:
- Chemical and structural designing of nanomaterials for application in medicine and tissue engineering (RS-172026)
- Medical Faculty of the Military Medical Academy, University of Defence in Belgrade [MFVMA 10/13-15]
DOI: 10.1177/2280800018822252
ISSN: 2280-8000
PubMed: 34783619
WoS: 000720310600001
Scopus: 2-s2.0-85119144638
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VinčaTY - JOUR AU - Magić, Marko AU - Čolović, Božana M. AU - Vasilijić, Saša AU - Tadić, Nenad AU - Stojadinović, Stevan AU - Jokanović, Vukoman R. PY - 2021 UR - https://vinar.vin.bg.ac.rs/handle/123456789/10041 AB - The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells. T2 - Journal of Applied Biomaterials & Functional Materials T1 - Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity VL - 19 DO - 10.1177/2280800018822252 ER -
@article{ author = "Magić, Marko and Čolović, Božana M. and Vasilijić, Saša and Tadić, Nenad and Stojadinović, Stevan and Jokanović, Vukoman R.", year = "2021", abstract = "The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.", journal = "Journal of Applied Biomaterials & Functional Materials", title = "Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity", volume = "19", doi = "10.1177/2280800018822252" }
Magić, M., Čolović, B. M., Vasilijić, S., Tadić, N., Stojadinović, S.,& Jokanović, V. R.. (2021). Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity. in Journal of Applied Biomaterials & Functional Materials, 19. https://doi.org/10.1177/2280800018822252
Magić M, Čolović BM, Vasilijić S, Tadić N, Stojadinović S, Jokanović VR. Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity. in Journal of Applied Biomaterials & Functional Materials. 2021;19. doi:10.1177/2280800018822252 .
Magić, Marko, Čolović, Božana M., Vasilijić, Saša, Tadić, Nenad, Stojadinović, Stevan, Jokanović, Vukoman R., "Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity" in Journal of Applied Biomaterials & Functional Materials, 19 (2021), https://doi.org/10.1177/2280800018822252 . .