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Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity

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2021
Main article [PDF] (2.261Mb)
Authors
Magić, Marko
Čolović, Božana M.
Vasilijić, Saša
Tadić, Nenad
Stojadinović, Stevan
Jokanović, Vukoman R.
Article (Published version)
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Abstract
The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
Keywords:
implants / LDH assay / MTT assay / plasma electrolytic oxidation / Titanium
Source:
Journal of Applied Biomaterials & Functional Materials, 2021, 19
Funding / projects:
  • Chemical and structural designing of nanomaterials for application in medicine and tissue engineering (RS-172026)
  • Medical Faculty of the Military Medical Academy, University of Defence in Belgrade [MFVMA 10/13-15]

DOI: 10.1177/2280800018822252

ISSN: 2280-8000

PubMed: 34783619

WoS: 000720310600001

Scopus: 2-s2.0-85119144638
[ Google Scholar ]
1
URI
https://vinar.vin.bg.ac.rs/handle/123456789/10041
Collections
  • Radovi istraživača
Institution/Community
Vinča
TY  - JOUR
AU  - Magić, Marko
AU  - Čolović, Božana M.
AU  - Vasilijić, Saša
AU  - Tadić, Nenad
AU  - Stojadinović, Stevan
AU  - Jokanović, Vukoman R.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10041
AB  - The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
T2  - Journal of Applied Biomaterials & Functional Materials
T1  - Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
VL  - 19
DO  - 10.1177/2280800018822252
ER  - 
@article{
author = "Magić, Marko and Čolović, Božana M. and Vasilijić, Saša and Tadić, Nenad and Stojadinović, Stevan and Jokanović, Vukoman R.",
year = "2021",
abstract = "The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.",
journal = "Journal of Applied Biomaterials & Functional Materials",
title = "Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity",
volume = "19",
doi = "10.1177/2280800018822252"
}
Magić, M., Čolović, B. M., Vasilijić, S., Tadić, N., Stojadinović, S.,& Jokanović, V. R.. (2021). Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity. in Journal of Applied Biomaterials & Functional Materials, 19.
https://doi.org/10.1177/2280800018822252
Magić M, Čolović BM, Vasilijić S, Tadić N, Stojadinović S, Jokanović VR. Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity. in Journal of Applied Biomaterials & Functional Materials. 2021;19.
doi:10.1177/2280800018822252 .
Magić, Marko, Čolović, Božana M., Vasilijić, Saša, Tadić, Nenad, Stojadinović, Stevan, Jokanović, Vukoman R., "Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity" in Journal of Applied Biomaterials & Functional Materials, 19 (2021),
https://doi.org/10.1177/2280800018822252 . .

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