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Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease

Aranđelović, Jovana; Santrač, Anja; Batinić, Bojan; Todorović, Lidija; Stevanović, Vladimir; Tiruveedhula, Veera Venkata Naga Phani Babu; Sharmin, Dishary; Rashid, Farjana; Stanojević, Boban; Cook, James M.; Savić, Miroslav M.

TY  - JOUR
AU  - Aranđelović, Jovana
AU  - Santrač, Anja
AU  - Batinić, Bojan
AU  - Todorović, Lidija
AU  - Stevanović, Vladimir
AU  - Tiruveedhula, Veera Venkata Naga Phani Babu
AU  - Sharmin, Dishary
AU  - Rashid, Farjana
AU  - Stanojević, Boban
AU  - Cook, James M.
AU  - Savić, Miroslav M.
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10360
AB  - Aims GABAergic modulation involved in cognitive processing appears to be substantially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric modulators of α5 GABAA receptors (NAM and PAM, respectively) would affect social interaction, social, object and spatial memory, and neuroinflammation. Methods After 10-day treatment with PAM, NAM, or solvent, 6-month-old transgenic and non-transgenic 5xFAD mice underwent testing in a behavioral battery. Gene expressions of IL-1β, IL-6, TNF-α, GFAP, and IBA-1 were determined in hippocampus and prefrontal cortex by qPCR. Results PAM treatment impaired spatial learning in transgenic females compared to solvent-treated transgenic females, and social recognition in transgenic and non-transgenic males. NAM treatment declined social interaction in transgenic and non-transgenic males, while had beneficial effect on cognitive flexibility in non-transgenic males compared to solvent-treated non-transgenic males. Transgenic animals have not fully displayed cognitive symptoms, but neuroinflammation was confirmed. NAM reduced proinflammatory gene expressions in transgenic females and astrogliosis in transgenic males compared to pathological controls. Conclusion PAM and NAM failed to exert favorable behavioral effects in transgenic animals. Suppression of neuroinflammation obtained with NAM calls for more studies with GABAergic ligands in amyloid beta- and/or tau-dependent models with prominent neuroinflammation.
T2  - CNS Neuroscience & Therapeutics
T2  - CNS Neuroscience & Therapeutics
T1  - Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease
DO  - 10.1111/cns.13914
ER  - 
@article{
author = "Aranđelović, Jovana and Santrač, Anja and Batinić, Bojan and Todorović, Lidija and Stevanović, Vladimir and Tiruveedhula, Veera Venkata Naga Phani Babu and Sharmin, Dishary and Rashid, Farjana and Stanojević, Boban and Cook, James M. and Savić, Miroslav M.",
abstract = "Aims GABAergic modulation involved in cognitive processing appears to be substantially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric modulators of α5 GABAA receptors (NAM and PAM, respectively) would affect social interaction, social, object and spatial memory, and neuroinflammation. Methods After 10-day treatment with PAM, NAM, or solvent, 6-month-old transgenic and non-transgenic 5xFAD mice underwent testing in a behavioral battery. Gene expressions of IL-1β, IL-6, TNF-α, GFAP, and IBA-1 were determined in hippocampus and prefrontal cortex by qPCR. Results PAM treatment impaired spatial learning in transgenic females compared to solvent-treated transgenic females, and social recognition in transgenic and non-transgenic males. NAM treatment declined social interaction in transgenic and non-transgenic males, while had beneficial effect on cognitive flexibility in non-transgenic males compared to solvent-treated non-transgenic males. Transgenic animals have not fully displayed cognitive symptoms, but neuroinflammation was confirmed. NAM reduced proinflammatory gene expressions in transgenic females and astrogliosis in transgenic males compared to pathological controls. Conclusion PAM and NAM failed to exert favorable behavioral effects in transgenic animals. Suppression of neuroinflammation obtained with NAM calls for more studies with GABAergic ligands in amyloid beta- and/or tau-dependent models with prominent neuroinflammation.",
journal = "CNS Neuroscience & Therapeutics, CNS Neuroscience & Therapeutics",
title = "Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease",
doi = "10.1111/cns.13914"
}
Aranđelović, J., Santrač, A., Batinić, B., Todorović, L., Stevanović, V., Tiruveedhula, V. V. N. P. B., Sharmin, D., Rashid, F., Stanojević, B., Cook, J. M.,& Savić, M. M..Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease. in CNS Neuroscience & Therapeutics.
https://doi.org/10.1111/cns.13914
Aranđelović J, Santrač A, Batinić B, Todorović L, Stevanović V, Tiruveedhula VVNPB, Sharmin D, Rashid F, Stanojević B, Cook JM, Savić MM. Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease. in CNS Neuroscience & Therapeutics..
doi:10.1111/cns.13914 .
Aranđelović, Jovana, Santrač, Anja, Batinić, Bojan, Todorović, Lidija, Stevanović, Vladimir, Tiruveedhula, Veera Venkata Naga Phani Babu, Sharmin, Dishary, Rashid, Farjana, Stanojević, Boban, Cook, James M., Savić, Miroslav M., "Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease" in CNS Neuroscience & Therapeutics,
https://doi.org/10.1111/cns.13914 . .
10

Construction of Sensor for Submicromolar Detection of Riboflavin by Surface Modification of SPCE with Thermal Degradation Products of Nickel Acetate Tetrahydrate

Ognjanović, Miloš; Stanković, Dalibor M.; Jaćimović, Željko K.; Kosović-Perutović, Milica; Mariano, José F. M. L.; Krehula, Stjepko; Musić, Svetozar; Antić, Bratislav

TY  - JOUR
AU  - Ognjanović, Miloš
AU  - Stanković, Dalibor M.
AU  - Jaćimović, Željko K.
AU  - Kosović-Perutović, Milica
AU  - Mariano, José F. M. L.
AU  - Krehula, Stjepko
AU  - Musić, Svetozar
AU  - Antić, Bratislav
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10215
AB  - Nickel acetate tetrahydrate (NAT) sample series were used to modify screen-printed carbon electrodes (SPCE). The samples were hybrid Ni/NiO nanocomposites, where the NiO phase increased with an applied treatment temperature. Results of electrochemical measurements pointed that the Ni/NiO550/SPCE-modified electrode had the best analytical performance toward the detection of riboflavin (RF). The Ni/NiO550/SPCE-based sensor showed linear response with RF in the concentration range of 0.5–75 μM and 0.15 μM LOD in BRBS. Sensor offered fast response time, good repeatability, and selectivity with an RSD of 1.4 %. Our results show that the Ni:NiO nanocomposite ratio strongly influenced the electroanalytical performance of SPCE.
T2  - Electroanalysis
T1  - Construction of Sensor for Submicromolar Detection of Riboflavin by Surface Modification of SPCE with Thermal Degradation Products of Nickel Acetate Tetrahydrate
DO  - 10.1002/elan.202100602
ER  - 
@article{
author = "Ognjanović, Miloš and Stanković, Dalibor M. and Jaćimović, Željko K. and Kosović-Perutović, Milica and Mariano, José F. M. L. and Krehula, Stjepko and Musić, Svetozar and Antić, Bratislav",
abstract = "Nickel acetate tetrahydrate (NAT) sample series were used to modify screen-printed carbon electrodes (SPCE). The samples were hybrid Ni/NiO nanocomposites, where the NiO phase increased with an applied treatment temperature. Results of electrochemical measurements pointed that the Ni/NiO550/SPCE-modified electrode had the best analytical performance toward the detection of riboflavin (RF). The Ni/NiO550/SPCE-based sensor showed linear response with RF in the concentration range of 0.5–75 μM and 0.15 μM LOD in BRBS. Sensor offered fast response time, good repeatability, and selectivity with an RSD of 1.4 %. Our results show that the Ni:NiO nanocomposite ratio strongly influenced the electroanalytical performance of SPCE.",
journal = "Electroanalysis",
title = "Construction of Sensor for Submicromolar Detection of Riboflavin by Surface Modification of SPCE with Thermal Degradation Products of Nickel Acetate Tetrahydrate",
doi = "10.1002/elan.202100602"
}
Ognjanović, M., Stanković, D. M., Jaćimović, Ž. K., Kosović-Perutović, M., Mariano, J. F. M. L., Krehula, S., Musić, S.,& Antić, B..Construction of Sensor for Submicromolar Detection of Riboflavin by Surface Modification of SPCE with Thermal Degradation Products of Nickel Acetate Tetrahydrate. in Electroanalysis.
https://doi.org/10.1002/elan.202100602
Ognjanović M, Stanković DM, Jaćimović ŽK, Kosović-Perutović M, Mariano JFML, Krehula S, Musić S, Antić B. Construction of Sensor for Submicromolar Detection of Riboflavin by Surface Modification of SPCE with Thermal Degradation Products of Nickel Acetate Tetrahydrate. in Electroanalysis..
doi:10.1002/elan.202100602 .
Ognjanović, Miloš, Stanković, Dalibor M., Jaćimović, Željko K., Kosović-Perutović, Milica, Mariano, José F. M. L., Krehula, Stjepko, Musić, Svetozar, Antić, Bratislav, "Construction of Sensor for Submicromolar Detection of Riboflavin by Surface Modification of SPCE with Thermal Degradation Products of Nickel Acetate Tetrahydrate" in Electroanalysis,
https://doi.org/10.1002/elan.202100602 . .
1

Predicting the Heat of Hydride Formation by Graph Neural Network - Exploring the Structure-Property Relation for Metal Hydrides

Batalovic, Katarina; Radaković, Jana; Paskaš Mamula, Bojana; Kuzmanović, Bojana; Medić-Ilić, Mirjana

TY  - JOUR
AU  - Batalovic, Katarina
AU  - Radaković, Jana
AU  - Paskaš Mamula, Bojana
AU  - Kuzmanović, Bojana
AU  - Medić-Ilić, Mirjana
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10348
AB  - Theoretical tools or structure-property relations that enable the prediction of metal hydrides are of enormous interest in developing new hydrogen storage materials. Density functional theory (DFT) is one such approach that provides accurate hydride formation energies, which, if complemented with vibrational zero-point energy and other contributions, provides accurate hydride formation enthalpies. However, this approach is time consuming and, therefore, often avoided, hindering the modeling of experimental behavior. The recent implementation of graph neural networks (GNN) in materials science enables fast prediction of crystal formation energy with a DFT accuracy. Starting from the MatErials Graph Network (MEGNet), transfer learning is applied to develop a model for predicting hydride formation enthalpy based on the crystal structure of the starting intermetallic. Excellent accuracy is achieved for Mg-containing alloys, allowing the screening of the Mg-Ni-M ternary intermetallics. In addition, data containing matching experimental properties and crystal structure of metal hydrides are provided, enabling future development.
T2  - Advanced Theory and Simulations
T1  - Predicting the Heat of Hydride Formation by Graph Neural Network - Exploring the Structure-Property Relation for Metal Hydrides
SP  - 2200293
DO  - 10.1002/adts.202200293
ER  - 
@article{
author = "Batalovic, Katarina and Radaković, Jana and Paskaš Mamula, Bojana and Kuzmanović, Bojana and Medić-Ilić, Mirjana",
abstract = "Theoretical tools or structure-property relations that enable the prediction of metal hydrides are of enormous interest in developing new hydrogen storage materials. Density functional theory (DFT) is one such approach that provides accurate hydride formation energies, which, if complemented with vibrational zero-point energy and other contributions, provides accurate hydride formation enthalpies. However, this approach is time consuming and, therefore, often avoided, hindering the modeling of experimental behavior. The recent implementation of graph neural networks (GNN) in materials science enables fast prediction of crystal formation energy with a DFT accuracy. Starting from the MatErials Graph Network (MEGNet), transfer learning is applied to develop a model for predicting hydride formation enthalpy based on the crystal structure of the starting intermetallic. Excellent accuracy is achieved for Mg-containing alloys, allowing the screening of the Mg-Ni-M ternary intermetallics. In addition, data containing matching experimental properties and crystal structure of metal hydrides are provided, enabling future development.",
journal = "Advanced Theory and Simulations",
title = "Predicting the Heat of Hydride Formation by Graph Neural Network - Exploring the Structure-Property Relation for Metal Hydrides",
pages = "2200293",
doi = "10.1002/adts.202200293"
}
Batalovic, K., Radaković, J., Paskaš Mamula, B., Kuzmanović, B.,& Medić-Ilić, M..Predicting the Heat of Hydride Formation by Graph Neural Network - Exploring the Structure-Property Relation for Metal Hydrides. in Advanced Theory and Simulations, 2200293.
https://doi.org/10.1002/adts.202200293
Batalovic K, Radaković J, Paskaš Mamula B, Kuzmanović B, Medić-Ilić M. Predicting the Heat of Hydride Formation by Graph Neural Network - Exploring the Structure-Property Relation for Metal Hydrides. in Advanced Theory and Simulations.:2200293.
doi:10.1002/adts.202200293 .
Batalovic, Katarina, Radaković, Jana, Paskaš Mamula, Bojana, Kuzmanović, Bojana, Medić-Ilić, Mirjana, "Predicting the Heat of Hydride Formation by Graph Neural Network - Exploring the Structure-Property Relation for Metal Hydrides" in Advanced Theory and Simulations:2200293,
https://doi.org/10.1002/adts.202200293 . .
1

The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer

Marinković, Aleksandar; Vuksanović, Marija M.; Karić, Nataša; Đokić, Veljko; Popović, Mina; Jančić-Heinemann, Radmila; Tomić, Nataša

TY  - JOUR
AU  - Marinković, Aleksandar
AU  - Vuksanović, Marija M.
AU  - Karić, Nataša
AU  - Đokić, Veljko
AU  - Popović, Mina
AU  - Jančić-Heinemann, Radmila
AU  - Tomić, Nataša
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9761
AB  - As a renewable resource, starch is considered to be fully biodegradable and nonpolluting to the environment but the hygroscopicity of starch is the main disadvantage for wider applicability in the production of a polymer-based material. Hydrophobically modified starch prepared using natural-based plasticizers/modifiers in a first step ([-]-diisopropyl D-tartrate [DiPT], ricinoleic acid [RA] and epoxidized soybean oil [ESO]), and maleated polypropylene (MAPP) in a second step contributed to better compatibility, and thus reinforcing of composites. Tailored processing conditions, structural/morphological properties, hydrophobicity, and water-resistance of the modified starch were established. In addition, the Charpy impact and tensile strength of composites, based on poly(ethylene-co-acrylic acid) (EAA) and modified starches, were determined. Increased tensile strength and Young modulus of the composite using starch-modified with DiPT-MAPP, that is, 3 and 83%, respectively, indicated the possible applicability of obtained materials.
T2  - Polymer Composites
T1  - The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer
DO  - 10.1002/pc.25903
ER  - 
@article{
author = "Marinković, Aleksandar and Vuksanović, Marija M. and Karić, Nataša and Đokić, Veljko and Popović, Mina and Jančić-Heinemann, Radmila and Tomić, Nataša",
abstract = "As a renewable resource, starch is considered to be fully biodegradable and nonpolluting to the environment but the hygroscopicity of starch is the main disadvantage for wider applicability in the production of a polymer-based material. Hydrophobically modified starch prepared using natural-based plasticizers/modifiers in a first step ([-]-diisopropyl D-tartrate [DiPT], ricinoleic acid [RA] and epoxidized soybean oil [ESO]), and maleated polypropylene (MAPP) in a second step contributed to better compatibility, and thus reinforcing of composites. Tailored processing conditions, structural/morphological properties, hydrophobicity, and water-resistance of the modified starch were established. In addition, the Charpy impact and tensile strength of composites, based on poly(ethylene-co-acrylic acid) (EAA) and modified starches, were determined. Increased tensile strength and Young modulus of the composite using starch-modified with DiPT-MAPP, that is, 3 and 83%, respectively, indicated the possible applicability of obtained materials.",
journal = "Polymer Composites",
title = "The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer",
doi = "10.1002/pc.25903"
}
Marinković, A., Vuksanović, M. M., Karić, N., Đokić, V., Popović, M., Jančić-Heinemann, R.,& Tomić, N..The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer. in Polymer Composites.
https://doi.org/10.1002/pc.25903
Marinković A, Vuksanović MM, Karić N, Đokić V, Popović M, Jančić-Heinemann R, Tomić N. The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer. in Polymer Composites..
doi:10.1002/pc.25903 .
Marinković, Aleksandar, Vuksanović, Marija M., Karić, Nataša, Đokić, Veljko, Popović, Mina, Jančić-Heinemann, Radmila, Tomić, Nataša, "The effect of natural modifiers for starch hydrophobization on performance of composite based on ethylene acrylic acid copolymer" in Polymer Composites,
https://doi.org/10.1002/pc.25903 . .
2
2
2

Denture composite reinforced with short polyethylene terephthalate fibers

Perišić, Srđan; Kareem Ali Alzaroug, Azdihar; Kalevski, Katarina; Vuksanović, Marija M.; Volkov-Husović, Tatjana; Radović, Ivana; Radojević, Vesna

TY  - JOUR
AU  - Perišić, Srđan
AU  - Kareem Ali Alzaroug, Azdihar
AU  - Kalevski, Katarina
AU  - Vuksanović, Marija M.
AU  - Volkov-Husović, Tatjana
AU  - Radović, Ivana
AU  - Radojević, Vesna
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10053
AB  - Polymer matrix composite materials have found application in dentistry because of good mechanical properties, aesthetic, easy processing, and possibilities of the repair. Acrylates are materials used to make and repair dentures. Reinforcements in the form of short glass or polymer fibers are added to improve the mechanical properties of dental polymers. In this study, the processing of composite material with a polymer matrix from commercial auto-polymerized acrylate Simgal, with reinforcement in the form of short poly(ethylene terephthalate) (PET) fibers was examined. Samples were processed in three series: pure Simgal, Simgal/PET 1 wt% and Simgal/PET 3 wt%. The influence of the reinforcement in the form of short PET fibers on the mechanical properties of composite materials was investigated. Strength and hardness were tested by impact testing and Vickers microhardness, and it was shown that there is an increase in absorbed energy and hardness. The modulus was reduced by the addition of PET fibers and by increasing the amount of fibers in the composite. The increase in the amount of PET fibers also resulted in a smaller loss of surface mass of the samples compared to the pure matrix by 63% and 93%, respectively. Cavitation test revealed better cavitation resistance of composites than the pure acrylate.
T2  - Polymer Composites
T1  - Denture composite reinforced with short polyethylene terephthalate fibers
DO  - 10.1002/pc.26397
ER  - 
@article{
author = "Perišić, Srđan and Kareem Ali Alzaroug, Azdihar and Kalevski, Katarina and Vuksanović, Marija M. and Volkov-Husović, Tatjana and Radović, Ivana and Radojević, Vesna",
abstract = "Polymer matrix composite materials have found application in dentistry because of good mechanical properties, aesthetic, easy processing, and possibilities of the repair. Acrylates are materials used to make and repair dentures. Reinforcements in the form of short glass or polymer fibers are added to improve the mechanical properties of dental polymers. In this study, the processing of composite material with a polymer matrix from commercial auto-polymerized acrylate Simgal, with reinforcement in the form of short poly(ethylene terephthalate) (PET) fibers was examined. Samples were processed in three series: pure Simgal, Simgal/PET 1 wt% and Simgal/PET 3 wt%. The influence of the reinforcement in the form of short PET fibers on the mechanical properties of composite materials was investigated. Strength and hardness were tested by impact testing and Vickers microhardness, and it was shown that there is an increase in absorbed energy and hardness. The modulus was reduced by the addition of PET fibers and by increasing the amount of fibers in the composite. The increase in the amount of PET fibers also resulted in a smaller loss of surface mass of the samples compared to the pure matrix by 63% and 93%, respectively. Cavitation test revealed better cavitation resistance of composites than the pure acrylate.",
journal = "Polymer Composites",
title = "Denture composite reinforced with short polyethylene terephthalate fibers",
doi = "10.1002/pc.26397"
}
Perišić, S., Kareem Ali Alzaroug, A., Kalevski, K., Vuksanović, M. M., Volkov-Husović, T., Radović, I.,& Radojević, V..Denture composite reinforced with short polyethylene terephthalate fibers. in Polymer Composites.
https://doi.org/10.1002/pc.26397
Perišić S, Kareem Ali Alzaroug A, Kalevski K, Vuksanović MM, Volkov-Husović T, Radović I, Radojević V. Denture composite reinforced with short polyethylene terephthalate fibers. in Polymer Composites..
doi:10.1002/pc.26397 .
Perišić, Srđan, Kareem Ali Alzaroug, Azdihar, Kalevski, Katarina, Vuksanović, Marija M., Volkov-Husović, Tatjana, Radović, Ivana, Radojević, Vesna, "Denture composite reinforced with short polyethylene terephthalate fibers" in Polymer Composites,
https://doi.org/10.1002/pc.26397 . .
1

Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer

Stojković, Goran; Jovanović, Ivan; Dimitrijević, Milovan; Jovanović, Jasmina; Tomanović, Nada; Stanković, Aleksandra; Arsović, Nenad; Boričić, Ivan; Zeljić, Katarina

TY  - JOUR
AU  - Stojković, Goran
AU  - Jovanović, Ivan
AU  - Dimitrijević, Milovan
AU  - Jovanović, Jasmina
AU  - Tomanović, Nada
AU  - Stanković, Aleksandra
AU  - Arsović, Nenad
AU  - Boričić, Ivan
AU  - Zeljić, Katarina
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10217
AB  - Objectives This study aimed to experimentally validate dysregulated expression of miRNA candidates selected through updated meta-analysis of most commonly deregulated miRNAs in oral cancer and to explore their diagnostic and prognostic potential. Materials and methods Five miRNAs (miR-31-3p, miR-135b-5p, miR-18a-5p, miR-30a-5p and miR-139-5p) from updated meta-signature were selected for validation by qRT-PCR method in 35 oral cancer clinical specimens and adjacent non-cancerous tissue. Results Updated meta-analysis has identified 13 most commonly deregulated miRNAs in oral cancer. Seven miRNAs were consistently up-regulated (miR-21-5p, miR-31-3p, miR-135b-5p, miR-31-5p, miR-424-5p, miR-18a-5p and miR-21-3p), while five were down-regulated (miR-139-5p, miR-30a-3p, miR-375-3p, miR-376c-3p and miR-30a-5p). Increased expression of miR-31-3p and miR-135b-5p, and decreased expression of miR-139-5p and miR-30a-5p were confirmed in oral cancer compared to adjacent non-cancerous tissue. A three miRNAs combination (miR-31-3p, miR-139-5p and miR-30a-5p) gave the most promising diagnostic potential for discriminating oral cancer from non-cancerous tissue (AUC: 0.780 [95% CI: 0.673–0.886], p < 0.0005, sensitivity 94.3%, specificity 51.4%). High expression of miR-135b-5p, miR-18a-5p and miR-30a-5p was associated with poor survival (p = 0.003, p = 0.048, p = 0.016 respectively). Conclusion miR-31-3p, miR-139-5p and miR-30a-5p panel was confirmed as a potential diagnostic biomarker when distinguishing oral cancer from non-cancerous tissue. miR-135b-5p, miR-18a-5p and miR-30a-5p might serve as potential biomarkers of poor survival of oral cancer patients.
T2  - Oral Diseases
T1  - Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer
DO  - 10.1111/odi.14185
ER  - 
@article{
author = "Stojković, Goran and Jovanović, Ivan and Dimitrijević, Milovan and Jovanović, Jasmina and Tomanović, Nada and Stanković, Aleksandra and Arsović, Nenad and Boričić, Ivan and Zeljić, Katarina",
abstract = "Objectives This study aimed to experimentally validate dysregulated expression of miRNA candidates selected through updated meta-analysis of most commonly deregulated miRNAs in oral cancer and to explore their diagnostic and prognostic potential. Materials and methods Five miRNAs (miR-31-3p, miR-135b-5p, miR-18a-5p, miR-30a-5p and miR-139-5p) from updated meta-signature were selected for validation by qRT-PCR method in 35 oral cancer clinical specimens and adjacent non-cancerous tissue. Results Updated meta-analysis has identified 13 most commonly deregulated miRNAs in oral cancer. Seven miRNAs were consistently up-regulated (miR-21-5p, miR-31-3p, miR-135b-5p, miR-31-5p, miR-424-5p, miR-18a-5p and miR-21-3p), while five were down-regulated (miR-139-5p, miR-30a-3p, miR-375-3p, miR-376c-3p and miR-30a-5p). Increased expression of miR-31-3p and miR-135b-5p, and decreased expression of miR-139-5p and miR-30a-5p were confirmed in oral cancer compared to adjacent non-cancerous tissue. A three miRNAs combination (miR-31-3p, miR-139-5p and miR-30a-5p) gave the most promising diagnostic potential for discriminating oral cancer from non-cancerous tissue (AUC: 0.780 [95% CI: 0.673–0.886], p < 0.0005, sensitivity 94.3%, specificity 51.4%). High expression of miR-135b-5p, miR-18a-5p and miR-30a-5p was associated with poor survival (p = 0.003, p = 0.048, p = 0.016 respectively). Conclusion miR-31-3p, miR-139-5p and miR-30a-5p panel was confirmed as a potential diagnostic biomarker when distinguishing oral cancer from non-cancerous tissue. miR-135b-5p, miR-18a-5p and miR-30a-5p might serve as potential biomarkers of poor survival of oral cancer patients.",
journal = "Oral Diseases",
title = "Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer",
doi = "10.1111/odi.14185"
}
Stojković, G., Jovanović, I., Dimitrijević, M., Jovanović, J., Tomanović, N., Stanković, A., Arsović, N., Boričić, I.,& Zeljić, K..Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer. in Oral Diseases.
https://doi.org/10.1111/odi.14185
Stojković G, Jovanović I, Dimitrijević M, Jovanović J, Tomanović N, Stanković A, Arsović N, Boričić I, Zeljić K. Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer. in Oral Diseases..
doi:10.1111/odi.14185 .
Stojković, Goran, Jovanović, Ivan, Dimitrijević, Milovan, Jovanović, Jasmina, Tomanović, Nada, Stanković, Aleksandra, Arsović, Nenad, Boričić, Ivan, Zeljić, Katarina, "Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer" in Oral Diseases,
https://doi.org/10.1111/odi.14185 . .

Recent advances on smart glycoconjugate vaccines in infections and cancer

Anderluh, Marko; Berti, Francesco; Bzducha-Wróbel, Anna; Chiodo, Fabrizio; Colombo, Cinzia; Compostella, Federica; Durlik, Katarzyna; Ferhati, Xhenti; Holmdahl, Rikard; Jovanović, Dragana J.; Kaca, Wieslaw; Lay, Luigi; Marinovic-Cincovic, Milena; Marradi, Marco; Ozil, Musa; Polito, Laura; Reina, Josè Juan; Reis, Celso A.; Sackstein, Robert; Silipo, Alba; Švajger, Urban; Vaněk, Ondřej; Yamamoto, Fumiichiro; Richichi, Barbara; van Vliet, Sandra J.

TY  - JOUR
AU  - Anderluh, Marko
AU  - Berti, Francesco
AU  - Bzducha-Wróbel, Anna
AU  - Chiodo, Fabrizio
AU  - Colombo, Cinzia
AU  - Compostella, Federica
AU  - Durlik, Katarzyna
AU  - Ferhati, Xhenti
AU  - Holmdahl, Rikard
AU  - Jovanović, Dragana J.
AU  - Kaca, Wieslaw
AU  - Lay, Luigi
AU  - Marinovic-Cincovic, Milena
AU  - Marradi, Marco
AU  - Ozil, Musa
AU  - Polito, Laura
AU  - Reina, Josè Juan
AU  - Reis, Celso A.
AU  - Sackstein, Robert
AU  - Silipo, Alba
AU  - Švajger, Urban
AU  - Vaněk, Ondřej
AU  - Yamamoto, Fumiichiro
AU  - Richichi, Barbara
AU  - van Vliet, Sandra J.
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9834
AB  - Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, no effective vaccines are available for pathogens with a highly variable antigenic load, such as the human immunodeficiency virus or to induce cellular T-cell immunity in the fight against cancer. The recent SARS-CoV-2 outbreak has reinforced the relevance of designing smart therapeutic vaccine modalities to ensure public health. Indeed, academic and private companies have ongoing joint efforts to develop novel vaccine prototypes for this virus. Many pathogens are covered by a dense glycan-coat, which form an attractive target for vaccine development. Moreover, many tumor types are characterized by altered glycosylation profiles that are known as “tumor-associated carbohydrate antigens”. Unfortunately, glycans do not provoke a vigorous immune response and generally serve as T-cell-independent antigens, not eliciting protective immunoglobulin G responses nor inducing immunological memory. A close and continuous crosstalk between glycochemists and glycoimmunologists is essential for the successful development of efficient immune modulators. It is clear that this is a key point for the discovery of novel approaches, which could significantly improve our understanding of the immune system. In this review, we discuss the latest advancements in development of vaccines against glycan epitopes to gain selective immune responses and to provide an overview on the role of different immunogenic constructs in improving glycovaccine efficacy.
T2  - The FEBS Journal
T1  - Recent advances on smart glycoconjugate vaccines in infections and cancer
DO  - 10.1111/febs.15909
ER  - 
@article{
author = "Anderluh, Marko and Berti, Francesco and Bzducha-Wróbel, Anna and Chiodo, Fabrizio and Colombo, Cinzia and Compostella, Federica and Durlik, Katarzyna and Ferhati, Xhenti and Holmdahl, Rikard and Jovanović, Dragana J. and Kaca, Wieslaw and Lay, Luigi and Marinovic-Cincovic, Milena and Marradi, Marco and Ozil, Musa and Polito, Laura and Reina, Josè Juan and Reis, Celso A. and Sackstein, Robert and Silipo, Alba and Švajger, Urban and Vaněk, Ondřej and Yamamoto, Fumiichiro and Richichi, Barbara and van Vliet, Sandra J.",
abstract = "Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, no effective vaccines are available for pathogens with a highly variable antigenic load, such as the human immunodeficiency virus or to induce cellular T-cell immunity in the fight against cancer. The recent SARS-CoV-2 outbreak has reinforced the relevance of designing smart therapeutic vaccine modalities to ensure public health. Indeed, academic and private companies have ongoing joint efforts to develop novel vaccine prototypes for this virus. Many pathogens are covered by a dense glycan-coat, which form an attractive target for vaccine development. Moreover, many tumor types are characterized by altered glycosylation profiles that are known as “tumor-associated carbohydrate antigens”. Unfortunately, glycans do not provoke a vigorous immune response and generally serve as T-cell-independent antigens, not eliciting protective immunoglobulin G responses nor inducing immunological memory. A close and continuous crosstalk between glycochemists and glycoimmunologists is essential for the successful development of efficient immune modulators. It is clear that this is a key point for the discovery of novel approaches, which could significantly improve our understanding of the immune system. In this review, we discuss the latest advancements in development of vaccines against glycan epitopes to gain selective immune responses and to provide an overview on the role of different immunogenic constructs in improving glycovaccine efficacy.",
journal = "The FEBS Journal",
title = "Recent advances on smart glycoconjugate vaccines in infections and cancer",
doi = "10.1111/febs.15909"
}
Anderluh, M., Berti, F., Bzducha-Wróbel, A., Chiodo, F., Colombo, C., Compostella, F., Durlik, K., Ferhati, X., Holmdahl, R., Jovanović, D. J., Kaca, W., Lay, L., Marinovic-Cincovic, M., Marradi, M., Ozil, M., Polito, L., Reina, J. J., Reis, C. A., Sackstein, R., Silipo, A., Švajger, U., Vaněk, O., Yamamoto, F., Richichi, B.,& van Vliet, S. J..Recent advances on smart glycoconjugate vaccines in infections and cancer. in The FEBS Journal.
https://doi.org/10.1111/febs.15909
Anderluh M, Berti F, Bzducha-Wróbel A, Chiodo F, Colombo C, Compostella F, Durlik K, Ferhati X, Holmdahl R, Jovanović DJ, Kaca W, Lay L, Marinovic-Cincovic M, Marradi M, Ozil M, Polito L, Reina JJ, Reis CA, Sackstein R, Silipo A, Švajger U, Vaněk O, Yamamoto F, Richichi B, van Vliet SJ. Recent advances on smart glycoconjugate vaccines in infections and cancer. in The FEBS Journal..
doi:10.1111/febs.15909 .
Anderluh, Marko, Berti, Francesco, Bzducha-Wróbel, Anna, Chiodo, Fabrizio, Colombo, Cinzia, Compostella, Federica, Durlik, Katarzyna, Ferhati, Xhenti, Holmdahl, Rikard, Jovanović, Dragana J., Kaca, Wieslaw, Lay, Luigi, Marinovic-Cincovic, Milena, Marradi, Marco, Ozil, Musa, Polito, Laura, Reina, Josè Juan, Reis, Celso A., Sackstein, Robert, Silipo, Alba, Švajger, Urban, Vaněk, Ondřej, Yamamoto, Fumiichiro, Richichi, Barbara, van Vliet, Sandra J., "Recent advances on smart glycoconjugate vaccines in infections and cancer" in The FEBS Journal,
https://doi.org/10.1111/febs.15909 . .
15
13
4
9

Non-coding RNA and cholesteatoma

Jovanović, Ivan G.; Živković, Maja; Ješić, Snežana; Stanković, Aleksandra

TY  - JOUR
AU  - Jovanović, Ivan G.
AU  - Živković, Maja
AU  - Ješić, Snežana
AU  - Stanković, Aleksandra
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10115
AB  - Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master regulators orchestrating disease progression are still unknown. Therefore, in this review, we will discuss the diagnostic and therapeutic potential of non-coding RNAs (ncRNA) as a new class of regulatory molecules. Methods We have comprehensively reviewed all articles investigating ncRNAs, specifically micro RNAs (miRNAs) and long ncRNAs (lncRNA/circRNA) in cholesteatoma tissue. Results Candidate miRNA approaches indicated that miR-21 and let-7a are the major miRNAs involved in cholesteatoma growth, migration, proliferation, bone destruction, and apoptosis. Regulatory potential for the same biological processes was also observed for miR-203a. The NF-kB/miR-802/PTEN regulatory network was in relation to observed miR-21 activity in cholesteatoma as well. High throughput approaches revealed additional ncRNAs implicated in cholesteatoma pathology. Competitive endogenous RNA (ceRNA) analysis highlighted lncRNA/circRNA that could be “endogenous sponge” for miR-21 and let-7a based on the hypothesis that RNA transcripts can communicate with and regulate each other by using shared miRNA response elements. Conclusion In this review, we summarize the discoveries and role of ncRNA in major pathways in cholesteatoma and highlight the potential of miRNA-based therapeutics in the treatment of cholesteatoma. Level of Evidence: NA.
T2  - Laryngoscope Investigative Otolaryngology
T2  - Laryngoscope Investigative Otolaryngology
T1  - Non-coding RNA and cholesteatoma
DO  - 10.1002/lio2.728
ER  - 
@article{
author = "Jovanović, Ivan G. and Živković, Maja and Ješić, Snežana and Stanković, Aleksandra",
abstract = "Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master regulators orchestrating disease progression are still unknown. Therefore, in this review, we will discuss the diagnostic and therapeutic potential of non-coding RNAs (ncRNA) as a new class of regulatory molecules. Methods We have comprehensively reviewed all articles investigating ncRNAs, specifically micro RNAs (miRNAs) and long ncRNAs (lncRNA/circRNA) in cholesteatoma tissue. Results Candidate miRNA approaches indicated that miR-21 and let-7a are the major miRNAs involved in cholesteatoma growth, migration, proliferation, bone destruction, and apoptosis. Regulatory potential for the same biological processes was also observed for miR-203a. The NF-kB/miR-802/PTEN regulatory network was in relation to observed miR-21 activity in cholesteatoma as well. High throughput approaches revealed additional ncRNAs implicated in cholesteatoma pathology. Competitive endogenous RNA (ceRNA) analysis highlighted lncRNA/circRNA that could be “endogenous sponge” for miR-21 and let-7a based on the hypothesis that RNA transcripts can communicate with and regulate each other by using shared miRNA response elements. Conclusion In this review, we summarize the discoveries and role of ncRNA in major pathways in cholesteatoma and highlight the potential of miRNA-based therapeutics in the treatment of cholesteatoma. Level of Evidence: NA.",
journal = "Laryngoscope Investigative Otolaryngology, Laryngoscope Investigative Otolaryngology",
title = "Non-coding RNA and cholesteatoma",
doi = "10.1002/lio2.728"
}
Jovanović, I. G., Živković, M., Ješić, S.,& Stanković, A..Non-coding RNA and cholesteatoma. in Laryngoscope Investigative Otolaryngology.
https://doi.org/10.1002/lio2.728
Jovanović IG, Živković M, Ješić S, Stanković A. Non-coding RNA and cholesteatoma. in Laryngoscope Investigative Otolaryngology..
doi:10.1002/lio2.728 .
Jovanović, Ivan G., Živković, Maja, Ješić, Snežana, Stanković, Aleksandra, "Non-coding RNA and cholesteatoma" in Laryngoscope Investigative Otolaryngology,
https://doi.org/10.1002/lio2.728 . .
1

Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol

Kovačević, Nikola; Dapčević, Aleksandra; Ivković, Branka; Kachrimanis, Kyriakos; Mitrić, Miodrag; Ibrić, Svetlana; Medarević, Đorđe

TY  - JOUR
AU  - Kovačević, Nikola
AU  - Dapčević, Aleksandra
AU  - Ivković, Branka
AU  - Kachrimanis, Kyriakos
AU  - Mitrić, Miodrag
AU  - Ibrić, Svetlana
AU  - Medarević, Đorđe
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9932
AB  - In this study, four low molecular weight (LMW) excipients, tryptophan (TRY), phenylalanine (PHE), lysine (LYS) and saccharin (SAC) were evaluated as co-formers to generate co-amorphous systems (CAMS) by ball milling with carvedilol (CRV). Mixtures of CRV and LMW excipient in 1:0.5, 1:1 and 1:2 drug:excipient molar ratios were ball milled and analysed by powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), Fourier transform (FT-IR) infrared spectroscopy and dissolution testing. CAMS were formed by milling of a mixture of CRV with TRY in 1:2 M ratio and SAC in 1:1 M ratio, while amorphization of only CRV was achieved in other mixtures with SAC. In other samples containing TRY and PHE, milling resulted in partial amorphization, while LYS was the least suitable excipient for the amorphization of CRV. Unexpectedly, the highest supersaturation of CRV was achieved from samples containing CRV and LYS in 1:1 and 1:2 M ratios, despite the absence of a significant reduction in CRV crystallinity upon milling of these samples. Increase of hydrophobic surface area caused by milling of samples with TRY and PHE and agglomeration during dissolution testing of samples containing SAC are likely causes of poor dissolution performance of mixtures containing fully or partially amorphous CRV.
T2  - International Journal of Pharmaceutics
T1  - Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol
VL  - 608
DO  - 10.1016/j.ijpharm.2021.121033
ER  - 
@article{
author = "Kovačević, Nikola and Dapčević, Aleksandra and Ivković, Branka and Kachrimanis, Kyriakos and Mitrić, Miodrag and Ibrić, Svetlana and Medarević, Đorđe",
abstract = "In this study, four low molecular weight (LMW) excipients, tryptophan (TRY), phenylalanine (PHE), lysine (LYS) and saccharin (SAC) were evaluated as co-formers to generate co-amorphous systems (CAMS) by ball milling with carvedilol (CRV). Mixtures of CRV and LMW excipient in 1:0.5, 1:1 and 1:2 drug:excipient molar ratios were ball milled and analysed by powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), Fourier transform (FT-IR) infrared spectroscopy and dissolution testing. CAMS were formed by milling of a mixture of CRV with TRY in 1:2 M ratio and SAC in 1:1 M ratio, while amorphization of only CRV was achieved in other mixtures with SAC. In other samples containing TRY and PHE, milling resulted in partial amorphization, while LYS was the least suitable excipient for the amorphization of CRV. Unexpectedly, the highest supersaturation of CRV was achieved from samples containing CRV and LYS in 1:1 and 1:2 M ratios, despite the absence of a significant reduction in CRV crystallinity upon milling of these samples. Increase of hydrophobic surface area caused by milling of samples with TRY and PHE and agglomeration during dissolution testing of samples containing SAC are likely causes of poor dissolution performance of mixtures containing fully or partially amorphous CRV.",
journal = "International Journal of Pharmaceutics",
title = "Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol",
volume = "608",
doi = "10.1016/j.ijpharm.2021.121033"
}
Kovačević, N., Dapčević, A., Ivković, B., Kachrimanis, K., Mitrić, M., Ibrić, S.,& Medarević, Đ..Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol. in International Journal of Pharmaceutics, 608.
https://doi.org/10.1016/j.ijpharm.2021.121033
Kovačević N, Dapčević A, Ivković B, Kachrimanis K, Mitrić M, Ibrić S, Medarević Đ. Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol. in International Journal of Pharmaceutics.608.
doi:10.1016/j.ijpharm.2021.121033 .
Kovačević, Nikola, Dapčević, Aleksandra, Ivković, Branka, Kachrimanis, Kyriakos, Mitrić, Miodrag, Ibrić, Svetlana, Medarević, Đorđe, "Potential application of low molecular weight excipients for amorphization and dissolution enhancement of carvedilol" in International Journal of Pharmaceutics, 608,
https://doi.org/10.1016/j.ijpharm.2021.121033 . .
4
1
1

Artificial neural network modeling in environmental radioactivity studies – A review

Dragović, Snežana

(2022)

TY  - JOUR
AU  - Dragović, Snežana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10367
AB  - The development of nuclear technologies has directed environmental radioactivity research toward continuously improving existing and developing new models for different interpolation, optimization, and classification tasks. Due to their adaptability to new data without knowing the actual modeling function, artificial neural networks (ANNs) are extensively used to resolve the tasks for which the application of traditional statistical methods has not provided an adequate response. This study presents an overview of ANN-based modeling in environmental radioactivity studies, including identifying and quantifying radionuclides, predicting their migration in the environment, mapping their distribution, optimizing measurement methodologies, monitoring processes in nuclear plants, and real-time data analysis. Special attention is paid to highlighting the scope of the different case studies and discussing the techniques used in model development over time. The performances of ANNs are evaluated from the perspective of prediction accuracy, emphasizing the advantages and limitations encountered in their use. The most critical elements in model optimization were identified as network structure, selection of input parameters, the properties of input data set, and applied learning algorithm. The analysis of strategies and methods for improving the performance of ANNs has shown that developing integrated and hybrid artificial intelligent tools could provide a new path in environmental radioactivity modeling toward more reliable outcomes and higher accuracy predictions. The review highlights the potential of neural networks and challenges in their application in environmental radioactivity studies and proposes directions for future research.
T2  - Science of The Total Environment
T1  - Artificial neural network modeling in environmental radioactivity studies – A review
VL  - 847
SP  - 157526
DO  - 10.1016/j.scitotenv.2022.157526
ER  - 
@article{
author = "Dragović, Snežana",
year = "2022",
abstract = "The development of nuclear technologies has directed environmental radioactivity research toward continuously improving existing and developing new models for different interpolation, optimization, and classification tasks. Due to their adaptability to new data without knowing the actual modeling function, artificial neural networks (ANNs) are extensively used to resolve the tasks for which the application of traditional statistical methods has not provided an adequate response. This study presents an overview of ANN-based modeling in environmental radioactivity studies, including identifying and quantifying radionuclides, predicting their migration in the environment, mapping their distribution, optimizing measurement methodologies, monitoring processes in nuclear plants, and real-time data analysis. Special attention is paid to highlighting the scope of the different case studies and discussing the techniques used in model development over time. The performances of ANNs are evaluated from the perspective of prediction accuracy, emphasizing the advantages and limitations encountered in their use. The most critical elements in model optimization were identified as network structure, selection of input parameters, the properties of input data set, and applied learning algorithm. The analysis of strategies and methods for improving the performance of ANNs has shown that developing integrated and hybrid artificial intelligent tools could provide a new path in environmental radioactivity modeling toward more reliable outcomes and higher accuracy predictions. The review highlights the potential of neural networks and challenges in their application in environmental radioactivity studies and proposes directions for future research.",
journal = "Science of The Total Environment",
title = "Artificial neural network modeling in environmental radioactivity studies – A review",
volume = "847",
pages = "157526",
doi = "10.1016/j.scitotenv.2022.157526"
}
Dragović, S.. (2022). Artificial neural network modeling in environmental radioactivity studies – A review. in Science of The Total Environment, 847, 157526.
https://doi.org/10.1016/j.scitotenv.2022.157526
Dragović S. Artificial neural network modeling in environmental radioactivity studies – A review. in Science of The Total Environment. 2022;847:157526.
doi:10.1016/j.scitotenv.2022.157526 .
Dragović, Snežana, "Artificial neural network modeling in environmental radioactivity studies – A review" in Science of The Total Environment, 847 (2022):157526,
https://doi.org/10.1016/j.scitotenv.2022.157526 . .

Fabrication of zigzag and square spiral Cu nanostructures: Influence of substrate rotation on the structural, optical and electrical properties

Potočnik, Jelena; Božinović, Nevena; Popović, Maja; Barudžija, Tanja; Nenadović, Miloš; Novaković, Mirjana M.

(2022)

TY  - JOUR
AU  - Potočnik, Jelena
AU  - Božinović, Nevena
AU  - Popović, Maja
AU  - Barudžija, Tanja
AU  - Nenadović, Miloš
AU  - Novaković, Mirjana M.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10366
AB  - Copper (Cu) thin films were deposited by using glancing angle deposition in the form of zigzag and square spiral nanostructures. Thin films were fabricated under different azimuthal rotations (φ = 180°, 90°, 45°, 22.5° and 11°), to the thickness of approximately 300 nm. Morphological, chemical and structural properties were investigated by field-emission scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy and high-resolution transmission electron microscopy. For the optical characterization of the samples spectroscopic ellipsometry was used, while the electrical properties were analyzed by four-point probe method. It was found that as the azimuthal rotation decreases, deposited nanostructures become more porous with larger number of grown arms. Both, optical and electrical analyses revealed that the properties of the obtained thin films are significantly influenced by growth mechanism. By decreasing the φ parameter, the surface plasmon resonance peak was shifted from 1038.9 nm to 1676.6 nm, which can be correlated with the porosity of Cu structures. Besides, it was found that the optical and electrical properties of the thin films are also strongly dependent on the concentration of defects.
T2  - Journal of Alloys and Compounds
T1  - Fabrication of zigzag and square spiral Cu nanostructures: Influence of substrate rotation on the structural, optical and electrical properties
VL  - 922
SP  - 166211
DO  - 10.1016/j.jallcom.2022.166211
ER  - 
@article{
author = "Potočnik, Jelena and Božinović, Nevena and Popović, Maja and Barudžija, Tanja and Nenadović, Miloš and Novaković, Mirjana M.",
year = "2022",
abstract = "Copper (Cu) thin films were deposited by using glancing angle deposition in the form of zigzag and square spiral nanostructures. Thin films were fabricated under different azimuthal rotations (φ = 180°, 90°, 45°, 22.5° and 11°), to the thickness of approximately 300 nm. Morphological, chemical and structural properties were investigated by field-emission scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy and high-resolution transmission electron microscopy. For the optical characterization of the samples spectroscopic ellipsometry was used, while the electrical properties were analyzed by four-point probe method. It was found that as the azimuthal rotation decreases, deposited nanostructures become more porous with larger number of grown arms. Both, optical and electrical analyses revealed that the properties of the obtained thin films are significantly influenced by growth mechanism. By decreasing the φ parameter, the surface plasmon resonance peak was shifted from 1038.9 nm to 1676.6 nm, which can be correlated with the porosity of Cu structures. Besides, it was found that the optical and electrical properties of the thin films are also strongly dependent on the concentration of defects.",
journal = "Journal of Alloys and Compounds",
title = "Fabrication of zigzag and square spiral Cu nanostructures: Influence of substrate rotation on the structural, optical and electrical properties",
volume = "922",
pages = "166211",
doi = "10.1016/j.jallcom.2022.166211"
}
Potočnik, J., Božinović, N., Popović, M., Barudžija, T., Nenadović, M.,& Novaković, M. M.. (2022). Fabrication of zigzag and square spiral Cu nanostructures: Influence of substrate rotation on the structural, optical and electrical properties. in Journal of Alloys and Compounds, 922, 166211.
https://doi.org/10.1016/j.jallcom.2022.166211
Potočnik J, Božinović N, Popović M, Barudžija T, Nenadović M, Novaković MM. Fabrication of zigzag and square spiral Cu nanostructures: Influence of substrate rotation on the structural, optical and electrical properties. in Journal of Alloys and Compounds. 2022;922:166211.
doi:10.1016/j.jallcom.2022.166211 .
Potočnik, Jelena, Božinović, Nevena, Popović, Maja, Barudžija, Tanja, Nenadović, Miloš, Novaković, Mirjana M., "Fabrication of zigzag and square spiral Cu nanostructures: Influence of substrate rotation on the structural, optical and electrical properties" in Journal of Alloys and Compounds, 922 (2022):166211,
https://doi.org/10.1016/j.jallcom.2022.166211 . .

Optical properties of copper helical nanostructures: the effect of thickness on the SPR peak position

Potočnik, Jelena; Božinović, Nevena; Novaković, Mirjana M.; Barudžija, Tanja; Nenadović, Miloš; Popović, Maja

(2022)

TY  - JOUR
AU  - Potočnik, Jelena
AU  - Božinović, Nevena
AU  - Novaković, Mirjana M.
AU  - Barudžija, Tanja
AU  - Nenadović, Miloš
AU  - Popović, Maja
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10299
AB  - In this study, we have investigated the effect of thickness on the structural and optical properties of copper (Cu) helical nanostructures. Thin films with thicknesses of 160 nm, 280 nm, 450 nm, and 780 nm were obtained by e-beam glancing angle deposition. The morphology and the microstructure were studied by field emission scanning electron microscopy, x-ray diffraction and transmission electron microscopy, while for the optical analysis measurements spectroscopic ellipsometry was used. The results show that the deposited structures are porous with nanometer-sized crystallites preferentially oriented along (111) planes, as well as that the diameter of the helices increases with thickness. Detailed analyses of optical properties have demonstrated that the dielectric function of Cu structures is greatly influenced by the films thicknesses. With increasing thickness from 160 nm to 780 nm, the surface plasmon resonance peak was shifted from 1.31 eV to 1.05 eV, which was correlated with the growth mechanism and the size of deposited nanostructures.
T2  - Nanotechnology
T1  - Optical properties of copper helical nanostructures: the effect of thickness on the SPR peak position
VL  - 33
IS  - 34
SP  - 345710
DO  - 10.1088/1361-6528/ac705c
ER  - 
@article{
author = "Potočnik, Jelena and Božinović, Nevena and Novaković, Mirjana M. and Barudžija, Tanja and Nenadović, Miloš and Popović, Maja",
year = "2022",
abstract = "In this study, we have investigated the effect of thickness on the structural and optical properties of copper (Cu) helical nanostructures. Thin films with thicknesses of 160 nm, 280 nm, 450 nm, and 780 nm were obtained by e-beam glancing angle deposition. The morphology and the microstructure were studied by field emission scanning electron microscopy, x-ray diffraction and transmission electron microscopy, while for the optical analysis measurements spectroscopic ellipsometry was used. The results show that the deposited structures are porous with nanometer-sized crystallites preferentially oriented along (111) planes, as well as that the diameter of the helices increases with thickness. Detailed analyses of optical properties have demonstrated that the dielectric function of Cu structures is greatly influenced by the films thicknesses. With increasing thickness from 160 nm to 780 nm, the surface plasmon resonance peak was shifted from 1.31 eV to 1.05 eV, which was correlated with the growth mechanism and the size of deposited nanostructures.",
journal = "Nanotechnology",
title = "Optical properties of copper helical nanostructures: the effect of thickness on the SPR peak position",
volume = "33",
number = "34",
pages = "345710",
doi = "10.1088/1361-6528/ac705c"
}
Potočnik, J., Božinović, N., Novaković, M. M., Barudžija, T., Nenadović, M.,& Popović, M.. (2022). Optical properties of copper helical nanostructures: the effect of thickness on the SPR peak position. in Nanotechnology, 33(34), 345710.
https://doi.org/10.1088/1361-6528/ac705c
Potočnik J, Božinović N, Novaković MM, Barudžija T, Nenadović M, Popović M. Optical properties of copper helical nanostructures: the effect of thickness on the SPR peak position. in Nanotechnology. 2022;33(34):345710.
doi:10.1088/1361-6528/ac705c .
Potočnik, Jelena, Božinović, Nevena, Novaković, Mirjana M., Barudžija, Tanja, Nenadović, Miloš, Popović, Maja, "Optical properties of copper helical nanostructures: the effect of thickness on the SPR peak position" in Nanotechnology, 33, no. 34 (2022):345710,
https://doi.org/10.1088/1361-6528/ac705c . .

Influencing surface phenomena by Au diffusion in buffered TiO2-Au thin films: Effects of deposition and annealing processing

Milićević, Nemanja; Novaković, Mirjana M.; Potočnik, Jelena; Milović, Miloš; Rakočević, Lazar; Abazović, Nadica; Pjević, Dejan J.

(2022)

TY  - JOUR
AU  - Milićević, Nemanja
AU  - Novaković, Mirjana M.
AU  - Potočnik, Jelena
AU  - Milović, Miloš
AU  - Rakočević, Lazar
AU  - Abazović, Nadica
AU  - Pjević, Dejan J.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10194
AB  - Enhanced optical properties of TiO2 thin films can be achieved by doping or coating with metals. Metal-doped TiO2 can reduce electron-hole recombination and increase hydroxyl radical concentration on the surface of TiO2, resulting in increase of the photocatalytic activity. TiO2 and TiO2-Au thin films were obtained by DC magnetron sputtering of Ti target with Ar ions in O2 atmosphere. In the case of Au buffered TiO2 thin films, two different systems were deposited for comparison. Post deposition annealing at 400 °C was carried out in nitrogen atmosphere for 3 h. The structural and optical characteristics of the prepared films were investigated in detail by the combination of high-resolution microscopic and spectroscopic techniques. The photo-degradation rate was measured using Rhodamine B which simulated pollutant. Post deposition annealing resulted in diffusion of Au atoms through the layer as it was revealed by transmission electron microscopy and energy dispersive X-ray spectroscopy. The obtained TiO2 thin films were found to be amorphous after deposition and annealing at 400 °C leads to crystallization of anatase phase. Analysis of the binding energy in the corresponding X-ray photoelectron spectra has confirmed stoichiometry of TiO2 and that concentration of Au on the surface can be controlled by sputtering and annealing conditions, thus changing optical properties by influencing the surface plasmonic nature. All Au doped TiO2 thin films exhibited enhanced wettability and photo-degradation rates when compared to pristine titania films. © 2022 Elsevier B.V.
T2  - Surfaces and Interfaces
T1  - Influencing surface phenomena by Au diffusion in buffered TiO2-Au thin films: Effects of deposition and annealing processing
VL  - 30
SP  - 101811
DO  - 10.1016/j.surfin.2022.101811
ER  - 
@article{
author = "Milićević, Nemanja and Novaković, Mirjana M. and Potočnik, Jelena and Milović, Miloš and Rakočević, Lazar and Abazović, Nadica and Pjević, Dejan J.",
year = "2022",
abstract = "Enhanced optical properties of TiO2 thin films can be achieved by doping or coating with metals. Metal-doped TiO2 can reduce electron-hole recombination and increase hydroxyl radical concentration on the surface of TiO2, resulting in increase of the photocatalytic activity. TiO2 and TiO2-Au thin films were obtained by DC magnetron sputtering of Ti target with Ar ions in O2 atmosphere. In the case of Au buffered TiO2 thin films, two different systems were deposited for comparison. Post deposition annealing at 400 °C was carried out in nitrogen atmosphere for 3 h. The structural and optical characteristics of the prepared films were investigated in detail by the combination of high-resolution microscopic and spectroscopic techniques. The photo-degradation rate was measured using Rhodamine B which simulated pollutant. Post deposition annealing resulted in diffusion of Au atoms through the layer as it was revealed by transmission electron microscopy and energy dispersive X-ray spectroscopy. The obtained TiO2 thin films were found to be amorphous after deposition and annealing at 400 °C leads to crystallization of anatase phase. Analysis of the binding energy in the corresponding X-ray photoelectron spectra has confirmed stoichiometry of TiO2 and that concentration of Au on the surface can be controlled by sputtering and annealing conditions, thus changing optical properties by influencing the surface plasmonic nature. All Au doped TiO2 thin films exhibited enhanced wettability and photo-degradation rates when compared to pristine titania films. © 2022 Elsevier B.V.",
journal = "Surfaces and Interfaces",
title = "Influencing surface phenomena by Au diffusion in buffered TiO2-Au thin films: Effects of deposition and annealing processing",
volume = "30",
pages = "101811",
doi = "10.1016/j.surfin.2022.101811"
}
Milićević, N., Novaković, M. M., Potočnik, J., Milović, M., Rakočević, L., Abazović, N.,& Pjević, D. J.. (2022). Influencing surface phenomena by Au diffusion in buffered TiO2-Au thin films: Effects of deposition and annealing processing. in Surfaces and Interfaces, 30, 101811.
https://doi.org/10.1016/j.surfin.2022.101811
Milićević N, Novaković MM, Potočnik J, Milović M, Rakočević L, Abazović N, Pjević DJ. Influencing surface phenomena by Au diffusion in buffered TiO2-Au thin films: Effects of deposition and annealing processing. in Surfaces and Interfaces. 2022;30:101811.
doi:10.1016/j.surfin.2022.101811 .
Milićević, Nemanja, Novaković, Mirjana M., Potočnik, Jelena, Milović, Miloš, Rakočević, Lazar, Abazović, Nadica, Pjević, Dejan J., "Influencing surface phenomena by Au diffusion in buffered TiO2-Au thin films: Effects of deposition and annealing processing" in Surfaces and Interfaces, 30 (2022):101811,
https://doi.org/10.1016/j.surfin.2022.101811 . .

Optimal airfoil design and wing analysis for solar-powered high altitude platform station

Hasan, Mohammad Sakib; Svorcan, Jelena M.; Simonović, Aleksandar M.; Mirkov, Nikola S.; Kostić, Olivera P.

(2022)

TY  - JOUR
AU  - Hasan, Mohammad Sakib
AU  - Svorcan, Jelena M.
AU  - Simonović, Aleksandar M.
AU  - Mirkov, Nikola S.
AU  - Kostić, Olivera P.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10306
AB  - The ability of flying continuously over prolonged periods of time has become target of numerous research studies performed in recent years in both the fields of civil aviation and unmanned drones. High altitude platform stations are aircrafts that can operate for an extended period of time at altitudes 17 km above sea level and higher. The aim of this paper is to design and optimize a wing for such platforms and computationally investigate its aerodynamic performance. For that purpose, two-objective genetic algorithm, class shape transformation and panel method were combined and used to define different airfoils with the highest lift-to-drag ratio and maximal lift coefficient. Once the most suitable airfoil was chosen, polyhedral half-wing was modeled and its aerodynamic performances were estimated using the CFD approach. Flow simulations of transitional flow at various angles-of-attack were realized in ANSYS FLUENT and various quantitative and qualitative results are presented, such as aerodynamic coefficient curves and flow visualizations. In the end, daily mission of the aircraft is simulated and its energy requirement is estimated. In order to be able to cruise above Serbia in July, an aircraft weighing 150 kg must accumulate 17 kWh of solar energy per day.
T2  - Thermal Science
T1  - Optimal airfoil design and wing analysis for solar-powered high altitude platform station
VL  - 26
IS  - 3 Part A
SP  - 2163
EP  - 2175
DO  - 10.2298/TSCI210419241S
ER  - 
@article{
author = "Hasan, Mohammad Sakib and Svorcan, Jelena M. and Simonović, Aleksandar M. and Mirkov, Nikola S. and Kostić, Olivera P.",
year = "2022",
abstract = "The ability of flying continuously over prolonged periods of time has become target of numerous research studies performed in recent years in both the fields of civil aviation and unmanned drones. High altitude platform stations are aircrafts that can operate for an extended period of time at altitudes 17 km above sea level and higher. The aim of this paper is to design and optimize a wing for such platforms and computationally investigate its aerodynamic performance. For that purpose, two-objective genetic algorithm, class shape transformation and panel method were combined and used to define different airfoils with the highest lift-to-drag ratio and maximal lift coefficient. Once the most suitable airfoil was chosen, polyhedral half-wing was modeled and its aerodynamic performances were estimated using the CFD approach. Flow simulations of transitional flow at various angles-of-attack were realized in ANSYS FLUENT and various quantitative and qualitative results are presented, such as aerodynamic coefficient curves and flow visualizations. In the end, daily mission of the aircraft is simulated and its energy requirement is estimated. In order to be able to cruise above Serbia in July, an aircraft weighing 150 kg must accumulate 17 kWh of solar energy per day.",
journal = "Thermal Science",
title = "Optimal airfoil design and wing analysis for solar-powered high altitude platform station",
volume = "26",
number = "3 Part A",
pages = "2163-2175",
doi = "10.2298/TSCI210419241S"
}
Hasan, M. S., Svorcan, J. M., Simonović, A. M., Mirkov, N. S.,& Kostić, O. P.. (2022). Optimal airfoil design and wing analysis for solar-powered high altitude platform station. in Thermal Science, 26(3 Part A), 2163-2175.
https://doi.org/10.2298/TSCI210419241S
Hasan MS, Svorcan JM, Simonović AM, Mirkov NS, Kostić OP. Optimal airfoil design and wing analysis for solar-powered high altitude platform station. in Thermal Science. 2022;26(3 Part A):2163-2175.
doi:10.2298/TSCI210419241S .
Hasan, Mohammad Sakib, Svorcan, Jelena M., Simonović, Aleksandar M., Mirkov, Nikola S., Kostić, Olivera P., "Optimal airfoil design and wing analysis for solar-powered high altitude platform station" in Thermal Science, 26, no. 3 Part A (2022):2163-2175,
https://doi.org/10.2298/TSCI210419241S . .

New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies

Dražić, Branka; Antonijević-Nikolić, Mirjana; Marinović-Cincović, Milena; Živković-Radovanović, Vukosava; Borović, Branka; Tanasković, Slađana B.

(2022)

TY  - JOUR
AU  - Dražić, Branka
AU  - Antonijević-Nikolić, Mirjana
AU  - Marinović-Cincović, Milena
AU  - Živković-Radovanović, Vukosava
AU  - Borović, Branka
AU  - Tanasković, Slađana B.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10365
AB  - Two new cationic Cu(II) complexes of cyclam (1,4,8,11-tetraazacyclotetradecane) and aminocarboxylate coligands glycine or alanine have been synthesized. The complexes were characterized by elemental analysis (C, H and N), molar electrical conductivity, magnetic susceptibility measurement at room temperature, spectral methods (UV/Vis and Fourier transform infrared), as well as by thermogravimetric (TG) and differential thermal analysis (DTA). The analytical data of the complexes show the formation of mononuclear complexes with general formula [Cu(L)cyc](ClO4)2·nH2O, A) L = glycine, n = 1.5 and B) L = alanine, n = 2.5. The tetradentate ligand cyclam was coordinated to metals through four N donors. The spectroscopic data suggested that the amino carboxylate ligands coordinated via their carboxylate ion moieties. The six- -coordinate octahedral geometry around Cu(II) in both complexes was presumed. TG-DTA analysis indicated that complex B decomposed exothermally in a single step in the range of 310–400°C. The cytotoxic activity of Cu(II) complexes and the starting ligands were tested against human cervix adenocarcinoma cell line (HeLa), human melanoma (FemX) and human colon carcinoma (LS174). The IC50 values for the Cu(II) complexes were from 48.35–82.25 μM. Both complexes were tested for their antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast Candida albicans.
T2  - Journal of the Serbian Chemical Society
T1  - New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies
VL  - 87
IS  - 4
SP  - 451
EP  - 464
DO  - 10.2298/JSC211107026D
ER  - 
@article{
author = "Dražić, Branka and Antonijević-Nikolić, Mirjana and Marinović-Cincović, Milena and Živković-Radovanović, Vukosava and Borović, Branka and Tanasković, Slađana B.",
year = "2022",
abstract = "Two new cationic Cu(II) complexes of cyclam (1,4,8,11-tetraazacyclotetradecane) and aminocarboxylate coligands glycine or alanine have been synthesized. The complexes were characterized by elemental analysis (C, H and N), molar electrical conductivity, magnetic susceptibility measurement at room temperature, spectral methods (UV/Vis and Fourier transform infrared), as well as by thermogravimetric (TG) and differential thermal analysis (DTA). The analytical data of the complexes show the formation of mononuclear complexes with general formula [Cu(L)cyc](ClO4)2·nH2O, A) L = glycine, n = 1.5 and B) L = alanine, n = 2.5. The tetradentate ligand cyclam was coordinated to metals through four N donors. The spectroscopic data suggested that the amino carboxylate ligands coordinated via their carboxylate ion moieties. The six- -coordinate octahedral geometry around Cu(II) in both complexes was presumed. TG-DTA analysis indicated that complex B decomposed exothermally in a single step in the range of 310–400°C. The cytotoxic activity of Cu(II) complexes and the starting ligands were tested against human cervix adenocarcinoma cell line (HeLa), human melanoma (FemX) and human colon carcinoma (LS174). The IC50 values for the Cu(II) complexes were from 48.35–82.25 μM. Both complexes were tested for their antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast Candida albicans.",
journal = "Journal of the Serbian Chemical Society",
title = "New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies",
volume = "87",
number = "4",
pages = "451-464",
doi = "10.2298/JSC211107026D"
}
Dražić, B., Antonijević-Nikolić, M., Marinović-Cincović, M., Živković-Radovanović, V., Borović, B.,& Tanasković, S. B.. (2022). New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies. in Journal of the Serbian Chemical Society, 87(4), 451-464.
https://doi.org/10.2298/JSC211107026D
Dražić B, Antonijević-Nikolić M, Marinović-Cincović M, Živković-Radovanović V, Borović B, Tanasković SB. New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies. in Journal of the Serbian Chemical Society. 2022;87(4):451-464.
doi:10.2298/JSC211107026D .
Dražić, Branka, Antonijević-Nikolić, Mirjana, Marinović-Cincović, Milena, Živković-Radovanović, Vukosava, Borović, Branka, Tanasković, Slađana B., "New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies" in Journal of the Serbian Chemical Society, 87, no. 4 (2022):451-464,
https://doi.org/10.2298/JSC211107026D . .

Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil

Đorđević, Кatarina Lj.; Galović, Slobodanka; Popović, Marica N.; Nešić, Mioljub V.; Stanimirović, Ivanka P.; Stanimirović, Zdravko I.; Markushev, Dragan D.

(2022)

TY  - JOUR
AU  - Đorđević, Кatarina Lj.
AU  - Galović, Slobodanka
AU  - Popović, Marica N.
AU  - Nešić, Mioljub V.
AU  - Stanimirović, Ivanka P.
AU  - Stanimirović, Zdravko I.
AU  - Markushev, Dragan D.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10364
AB  - The objective of this paper is to present methodology of the precise and reliable determination of thermal diffusivity and linear coefficient of thermal expansion of the photoacoustic signal recorded (obtained) using open photoacoustic cell where thickness of the sample served as a control parameter. The methodology was based on the application of neural networks that were trained on numerical experiments and optimized by adding Gaussian noise to the training base that corresponded in percentage to maximum measurement uncertainty. By comparing the predictions of the neural network with theoretical fitting curve for experimental results for the aluminum sample that was 197 μm thick, it was shown that the proposed methodology achieves high precision in the determination of thermoelastic and geometrical properties of the sample.
T2  - Measurement
T1  - Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil
SP  - 111537
DO  - 10.1016/j.measurement.2022.111537
ER  - 
@article{
author = "Đorđević, Кatarina Lj. and Galović, Slobodanka and Popović, Marica N. and Nešić, Mioljub V. and Stanimirović, Ivanka P. and Stanimirović, Zdravko I. and Markushev, Dragan D.",
year = "2022",
abstract = "The objective of this paper is to present methodology of the precise and reliable determination of thermal diffusivity and linear coefficient of thermal expansion of the photoacoustic signal recorded (obtained) using open photoacoustic cell where thickness of the sample served as a control parameter. The methodology was based on the application of neural networks that were trained on numerical experiments and optimized by adding Gaussian noise to the training base that corresponded in percentage to maximum measurement uncertainty. By comparing the predictions of the neural network with theoretical fitting curve for experimental results for the aluminum sample that was 197 μm thick, it was shown that the proposed methodology achieves high precision in the determination of thermoelastic and geometrical properties of the sample.",
journal = "Measurement",
title = "Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil",
pages = "111537",
doi = "10.1016/j.measurement.2022.111537"
}
Đorđević, К. Lj., Galović, S., Popović, M. N., Nešić, M. V., Stanimirović, I. P., Stanimirović, Z. I.,& Markushev, D. D.. (2022). Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil. in Measurement, 111537.
https://doi.org/10.1016/j.measurement.2022.111537
Đorđević КL, Galović S, Popović MN, Nešić MV, Stanimirović IP, Stanimirović ZI, Markushev DD. Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil. in Measurement. 2022;:111537.
doi:10.1016/j.measurement.2022.111537 .
Đorđević, Кatarina Lj., Galović, Slobodanka, Popović, Marica N., Nešić, Mioljub V., Stanimirović, Ivanka P., Stanimirović, Zdravko I., Markushev, Dragan D., "Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil" in Measurement (2022):111537,
https://doi.org/10.1016/j.measurement.2022.111537 . .

Dual-emission luminescence thermometry using LaGaO3:Cr3+, Nd3+ phosphors

Mullins, Abbi L.; Ćirić, Aleksandar; Zeković, Ivana; Williams, J. A. Gareth; Dramićanin, Miroslav; Radosavjević Evans, Ivana

(2022)

TY  - JOUR
AU  - Mullins, Abbi L.
AU  - Ćirić, Aleksandar
AU  - Zeković, Ivana
AU  - Williams, J. A. Gareth
AU  - Dramićanin, Miroslav
AU  - Radosavjević Evans, Ivana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10362
AB  - A series of La1−xGa0.99O3:Cr0.01, Ndx phosphors (where x = 0.005, 0.01, 0.02) for luminescence thermometry was synthesised by the solid-state method, structurally characterised using powder X-ray diffraction data, and investigated by ambient and variable-temperature optical measurements. The design principle relies on the use of a combination of transition metal and rare earth activator ions such that the excitation and emission wavelengths fall within the near infra-red spectral region, notably in the ‘first biological window’ that is attractive for potential in vivo applications. The photoluminescence spectra of the compounds feature the characteristic 2E phosphorescence of Cr3+ at 729 nm and the 4F3/2 → 4I9/2 emission of Nd3+ around 890 nm. The Nd3+ emission is quenched at a higher rate than that of Cr3+ with increasing temperature. Thermometric analysis by monitoring the luminescence intensity ratio (LIR) between the emissions of Cr3+ and Nd3+ from 300 K to 650 K shows a quasi-Boltzmann trend, with a maximum relative sensitivity of ∼2% K−1, high absolute sensitivity values over this entire temperature range, excellent temperature resolution of 0.04 K at room temperature, and high stability.
T2  - Journal of Materials Chemistry C
T1  - Dual-emission luminescence thermometry using LaGaO3:Cr3+, Nd3+ phosphors
VL  - 10
IS  - 28
SP  - 10396
EP  - 10403
DO  - 10.1039/D2TC02011D
ER  - 
@article{
author = "Mullins, Abbi L. and Ćirić, Aleksandar and Zeković, Ivana and Williams, J. A. Gareth and Dramićanin, Miroslav and Radosavjević Evans, Ivana",
year = "2022",
abstract = "A series of La1−xGa0.99O3:Cr0.01, Ndx phosphors (where x = 0.005, 0.01, 0.02) for luminescence thermometry was synthesised by the solid-state method, structurally characterised using powder X-ray diffraction data, and investigated by ambient and variable-temperature optical measurements. The design principle relies on the use of a combination of transition metal and rare earth activator ions such that the excitation and emission wavelengths fall within the near infra-red spectral region, notably in the ‘first biological window’ that is attractive for potential in vivo applications. The photoluminescence spectra of the compounds feature the characteristic 2E phosphorescence of Cr3+ at 729 nm and the 4F3/2 → 4I9/2 emission of Nd3+ around 890 nm. The Nd3+ emission is quenched at a higher rate than that of Cr3+ with increasing temperature. Thermometric analysis by monitoring the luminescence intensity ratio (LIR) between the emissions of Cr3+ and Nd3+ from 300 K to 650 K shows a quasi-Boltzmann trend, with a maximum relative sensitivity of ∼2% K−1, high absolute sensitivity values over this entire temperature range, excellent temperature resolution of 0.04 K at room temperature, and high stability.",
journal = "Journal of Materials Chemistry C",
title = "Dual-emission luminescence thermometry using LaGaO3:Cr3+, Nd3+ phosphors",
volume = "10",
number = "28",
pages = "10396-10403",
doi = "10.1039/D2TC02011D"
}
Mullins, A. L., Ćirić, A., Zeković, I., Williams, J. A. G., Dramićanin, M.,& Radosavjević Evans, I.. (2022). Dual-emission luminescence thermometry using LaGaO3:Cr3+, Nd3+ phosphors. in Journal of Materials Chemistry C, 10(28), 10396-10403.
https://doi.org/10.1039/D2TC02011D
Mullins AL, Ćirić A, Zeković I, Williams JAG, Dramićanin M, Radosavjević Evans I. Dual-emission luminescence thermometry using LaGaO3:Cr3+, Nd3+ phosphors. in Journal of Materials Chemistry C. 2022;10(28):10396-10403.
doi:10.1039/D2TC02011D .
Mullins, Abbi L., Ćirić, Aleksandar, Zeković, Ivana, Williams, J. A. Gareth, Dramićanin, Miroslav, Radosavjević Evans, Ivana, "Dual-emission luminescence thermometry using LaGaO3:Cr3+, Nd3+ phosphors" in Journal of Materials Chemistry C, 10, no. 28 (2022):10396-10403,
https://doi.org/10.1039/D2TC02011D . .

Novel composite based on zirconia and graphite. First results of application for synthetic dyes removal

Stepić, Katarina; Ljupković, Radomir; Zarubica, Aleksandra; Đorđijevski, Stefan; Matović, Branko; Krstić, Jugoslav; Bojić, Aleksandar

(2022)

TY  - JOUR
AU  - Stepić, Katarina
AU  - Ljupković, Radomir
AU  - Zarubica, Aleksandra
AU  - Đorđijevski, Stefan
AU  - Matović, Branko
AU  - Krstić, Jugoslav
AU  - Bojić, Aleksandar
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10361
AB  - In this research composite based on zirconia and graphite was synthesized using the sol-gel method. Aim of this research is to activate and increase the photocatalytic activity of ZrO2 by combining with graphite-based material. Our results show that we obtained material that can remove both cationic and anionic dyes by sorption and photocatalytic processes. Obtained composite is very effective in sorption of RB19 with up to 100% removal. Photocatalytic activity of composite is higher than pristine GO and goes up to 100% for RB19 degradation and about 50% degradation of MB. These results are promising and present an excellent base for further research. © 2022, Universitatea Babes-Bolyai, Catedra de Filosofie Sistematica. All rights reserved.
T2  - Studia Universitatis Babes-Bolyai Chemia
T1  - Novel composite based on zirconia and graphite. First results of application for synthetic dyes removal
VL  - 67
IS  - 2
SP  - 23
EP  - 43
DO  - 10.24193/subbchem.2022.2.02
ER  - 
@article{
author = "Stepić, Katarina and Ljupković, Radomir and Zarubica, Aleksandra and Đorđijevski, Stefan and Matović, Branko and Krstić, Jugoslav and Bojić, Aleksandar",
year = "2022",
abstract = "In this research composite based on zirconia and graphite was synthesized using the sol-gel method. Aim of this research is to activate and increase the photocatalytic activity of ZrO2 by combining with graphite-based material. Our results show that we obtained material that can remove both cationic and anionic dyes by sorption and photocatalytic processes. Obtained composite is very effective in sorption of RB19 with up to 100% removal. Photocatalytic activity of composite is higher than pristine GO and goes up to 100% for RB19 degradation and about 50% degradation of MB. These results are promising and present an excellent base for further research. © 2022, Universitatea Babes-Bolyai, Catedra de Filosofie Sistematica. All rights reserved.",
journal = "Studia Universitatis Babes-Bolyai Chemia",
title = "Novel composite based on zirconia and graphite. First results of application for synthetic dyes removal",
volume = "67",
number = "2",
pages = "23-43",
doi = "10.24193/subbchem.2022.2.02"
}
Stepić, K., Ljupković, R., Zarubica, A., Đorđijevski, S., Matović, B., Krstić, J.,& Bojić, A.. (2022). Novel composite based on zirconia and graphite. First results of application for synthetic dyes removal. in Studia Universitatis Babes-Bolyai Chemia, 67(2), 23-43.
https://doi.org/10.24193/subbchem.2022.2.02
Stepić K, Ljupković R, Zarubica A, Đorđijevski S, Matović B, Krstić J, Bojić A. Novel composite based on zirconia and graphite. First results of application for synthetic dyes removal. in Studia Universitatis Babes-Bolyai Chemia. 2022;67(2):23-43.
doi:10.24193/subbchem.2022.2.02 .
Stepić, Katarina, Ljupković, Radomir, Zarubica, Aleksandra, Đorđijevski, Stefan, Matović, Branko, Krstić, Jugoslav, Bojić, Aleksandar, "Novel composite based on zirconia and graphite. First results of application for synthetic dyes removal" in Studia Universitatis Babes-Bolyai Chemia, 67, no. 2 (2022):23-43,
https://doi.org/10.24193/subbchem.2022.2.02 . .

Influence of data scaling and normalization on overall neural network performances in photoacoustics

Đorđević, Katarina Lj.; Jordović-Pavlović, Miroslava I.; Ćojbašić, Ž. M.; Galović, Slobodanka; Popović, Marica N.; Nešić, Mioljub V.; Markushev, Dragan D.

(2022)

TY  - JOUR
AU  - Đorđević, Katarina Lj.
AU  - Jordović-Pavlović, Miroslava I.
AU  - Ćojbašić, Ž. M.
AU  - Galović, Slobodanka
AU  - Popović, Marica N.
AU  - Nešić, Mioljub V.
AU  - Markushev, Dragan D.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10359
AB  - In this paper, the influence of the input and output data scaling and normalization on the neural network overall performances is investigated aimed at inverse problem-solving in photoacoustics of semiconductors. The logarithmic scaling of the photoacoustic signal amplitudes as input data and numerical scaling of the sample thermal parameters as output data are presented as useful tools trying to reach maximal network precision. Max and min–max normalizations to the input data are presented to change their numerical values in the dataset to common scales, without distorting differences. It was demonstrated in theory that the largest network prediction error of all targeted parameters is obtained by a network with non-scaled output data. Also, it was found out that the best network prediction was achieved with min–max normalization of the input data and network predicted output data scale within the range of [1–10]. Network training and prediction performances analyzed with experimental input data show that the benefits and improvements of input and output scaling and normalization are not guaranteed but are strongly dependent on a specific problem to be solved.
T2  - Optical and Quantum Electronics
T1  - Influence of data scaling and normalization on overall neural network performances in photoacoustics
VL  - 54
IS  - 8
SP  - 501
DO  - 10.1007/s11082-022-03799-1
ER  - 
@article{
author = "Đorđević, Katarina Lj. and Jordović-Pavlović, Miroslava I. and Ćojbašić, Ž. M. and Galović, Slobodanka and Popović, Marica N. and Nešić, Mioljub V. and Markushev, Dragan D.",
year = "2022",
abstract = "In this paper, the influence of the input and output data scaling and normalization on the neural network overall performances is investigated aimed at inverse problem-solving in photoacoustics of semiconductors. The logarithmic scaling of the photoacoustic signal amplitudes as input data and numerical scaling of the sample thermal parameters as output data are presented as useful tools trying to reach maximal network precision. Max and min–max normalizations to the input data are presented to change their numerical values in the dataset to common scales, without distorting differences. It was demonstrated in theory that the largest network prediction error of all targeted parameters is obtained by a network with non-scaled output data. Also, it was found out that the best network prediction was achieved with min–max normalization of the input data and network predicted output data scale within the range of [1–10]. Network training and prediction performances analyzed with experimental input data show that the benefits and improvements of input and output scaling and normalization are not guaranteed but are strongly dependent on a specific problem to be solved.",
journal = "Optical and Quantum Electronics",
title = "Influence of data scaling and normalization on overall neural network performances in photoacoustics",
volume = "54",
number = "8",
pages = "501",
doi = "10.1007/s11082-022-03799-1"
}
Đorđević, K. Lj., Jordović-Pavlović, M. I., Ćojbašić, Ž. M., Galović, S., Popović, M. N., Nešić, M. V.,& Markushev, D. D.. (2022). Influence of data scaling and normalization on overall neural network performances in photoacoustics. in Optical and Quantum Electronics, 54(8), 501.
https://doi.org/10.1007/s11082-022-03799-1
Đorđević KL, Jordović-Pavlović MI, Ćojbašić ŽM, Galović S, Popović MN, Nešić MV, Markushev DD. Influence of data scaling and normalization on overall neural network performances in photoacoustics. in Optical and Quantum Electronics. 2022;54(8):501.
doi:10.1007/s11082-022-03799-1 .
Đorđević, Katarina Lj., Jordović-Pavlović, Miroslava I., Ćojbašić, Ž. M., Galović, Slobodanka, Popović, Marica N., Nešić, Mioljub V., Markushev, Dragan D., "Influence of data scaling and normalization on overall neural network performances in photoacoustics" in Optical and Quantum Electronics, 54, no. 8 (2022):501,
https://doi.org/10.1007/s11082-022-03799-1 . .

Luminescence thermometry with transition metal ions. A review

Marciniak, Lukasz; Kniec, Karolina; Elżbieciak-Piecka, Karolina; Trejgis, Karolina; Stefanska, Joanna Z.; Dramićanin, Miroslav

(2022)

TY  - JOUR
AU  - Marciniak, Lukasz
AU  - Kniec, Karolina
AU  - Elżbieciak-Piecka, Karolina
AU  - Trejgis, Karolina
AU  - Stefanska, Joanna Z.
AU  - Dramićanin, Miroslav
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10358
AB  - Transition metal (TM) ion activated phosphors are increasingly being used as probes for luminescence thermometry. Their luminescence is characterized by strong absorption and emission bands that span the visible and near-infrared spectral ranges and are highly susceptible to temperature variations. Due to the latter characteristic, sensitive and reliable remote temperature measurements can be performed by observing temperature-induced changes in TM ion emission intensities, emission bandwidths and bandshifts, and excited state lifetimes, as well as the temperature dependences of the intensity ratios between various emission bands in single or double activated phosphors. This review provides a systematic analysis of the performances of luminescent thermometers based on different TM ions and discusses the relations among the TM spectroscopic properties, characteristics of the host material structure, and thermometric performance. Particular attention is given to the engineering of energy transfer between TM and other dopant ions to obtain highly sensitive thermometers. Finally, several typical application examples from recent literature are highlighted. © 2022 The Author(s)
T2  - Coordination Chemistry Reviews
T2  - Coordination Chemistry Reviews
T1  - Luminescence thermometry with transition metal ions. A review
VL  - 469
DO  - 10.1016/j.ccr.2022.214671
ER  - 
@article{
author = "Marciniak, Lukasz and Kniec, Karolina and Elżbieciak-Piecka, Karolina and Trejgis, Karolina and Stefanska, Joanna Z. and Dramićanin, Miroslav",
year = "2022",
abstract = "Transition metal (TM) ion activated phosphors are increasingly being used as probes for luminescence thermometry. Their luminescence is characterized by strong absorption and emission bands that span the visible and near-infrared spectral ranges and are highly susceptible to temperature variations. Due to the latter characteristic, sensitive and reliable remote temperature measurements can be performed by observing temperature-induced changes in TM ion emission intensities, emission bandwidths and bandshifts, and excited state lifetimes, as well as the temperature dependences of the intensity ratios between various emission bands in single or double activated phosphors. This review provides a systematic analysis of the performances of luminescent thermometers based on different TM ions and discusses the relations among the TM spectroscopic properties, characteristics of the host material structure, and thermometric performance. Particular attention is given to the engineering of energy transfer between TM and other dopant ions to obtain highly sensitive thermometers. Finally, several typical application examples from recent literature are highlighted. © 2022 The Author(s)",
journal = "Coordination Chemistry Reviews, Coordination Chemistry Reviews",
title = "Luminescence thermometry with transition metal ions. A review",
volume = "469",
doi = "10.1016/j.ccr.2022.214671"
}
Marciniak, L., Kniec, K., Elżbieciak-Piecka, K., Trejgis, K., Stefanska, J. Z.,& Dramićanin, M.. (2022). Luminescence thermometry with transition metal ions. A review. in Coordination Chemistry Reviews, 469.
https://doi.org/10.1016/j.ccr.2022.214671
Marciniak L, Kniec K, Elżbieciak-Piecka K, Trejgis K, Stefanska JZ, Dramićanin M. Luminescence thermometry with transition metal ions. A review. in Coordination Chemistry Reviews. 2022;469.
doi:10.1016/j.ccr.2022.214671 .
Marciniak, Lukasz, Kniec, Karolina, Elżbieciak-Piecka, Karolina, Trejgis, Karolina, Stefanska, Joanna Z., Dramićanin, Miroslav, "Luminescence thermometry with transition metal ions. A review" in Coordination Chemistry Reviews, 469 (2022),
https://doi.org/10.1016/j.ccr.2022.214671 . .
1

Novel approach for strontium preconcentration from seawater and rapid determination of 89,90Sr in emergency situations

Coha, Ivana; Smičiklas, Ivana; Tucaković, Ivana; Jović, Mihajlo; Šljivić-Ivanović, Marija; Grahek, Željko

(2022)

TY  - JOUR
AU  - Coha, Ivana
AU  - Smičiklas, Ivana
AU  - Tucaković, Ivana
AU  - Jović, Mihajlo
AU  - Šljivić-Ivanović, Marija
AU  - Grahek, Željko
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10357
AB  - A novel approach for rapid 89,90Sr determination in seawater samples is developed. For the first time in the radioanalytical application, the features of the synthetic zeolite Z4A and a highly selective material for Sr separation were synergically employed. Seawater composition significantly reduces Sr yield on highly selective solid-phase extraction materials, making the preconcentration step essentially important but laborious and time-consuming. To address this issue, the ability of zeolite 4A to concentrate the Sr from the seawater matrix was employed. With the proposed method, two important goals were achieved: (i) simple preconcentration of Sr that can be conducted directly at the sampling site, enabling a rapid procedure for 89,90Sr determination in emergencies, and (ii) high and stable Sr recoveries (89 ± 4%) necessary for lowering detection limits. Strontium is effectively separated from 1 L of seawater in less than 1.5 h, which is especially important in emergency situations, such as the Fukushima Daiichi Nuclear Power Plant accident. Minimum detectable activities achieved for 89Sr:90Sr activity ratio ∼10:1 were 0.74 Bq/L for 89Sr, and 1.47 Bq/L for 90Sr, detected by Cherenkov counting, 36–38 h after separation, and 30 min counting time.
T2  - Talanta
T1  - Novel approach for strontium preconcentration from seawater and rapid determination of 89,90Sr in emergency situations
VL  - 250
SP  - 123722
DO  - 10.1016/j.talanta.2022.123722
ER  - 
@article{
author = "Coha, Ivana and Smičiklas, Ivana and Tucaković, Ivana and Jović, Mihajlo and Šljivić-Ivanović, Marija and Grahek, Željko",
year = "2022",
abstract = "A novel approach for rapid 89,90Sr determination in seawater samples is developed. For the first time in the radioanalytical application, the features of the synthetic zeolite Z4A and a highly selective material for Sr separation were synergically employed. Seawater composition significantly reduces Sr yield on highly selective solid-phase extraction materials, making the preconcentration step essentially important but laborious and time-consuming. To address this issue, the ability of zeolite 4A to concentrate the Sr from the seawater matrix was employed. With the proposed method, two important goals were achieved: (i) simple preconcentration of Sr that can be conducted directly at the sampling site, enabling a rapid procedure for 89,90Sr determination in emergencies, and (ii) high and stable Sr recoveries (89 ± 4%) necessary for lowering detection limits. Strontium is effectively separated from 1 L of seawater in less than 1.5 h, which is especially important in emergency situations, such as the Fukushima Daiichi Nuclear Power Plant accident. Minimum detectable activities achieved for 89Sr:90Sr activity ratio ∼10:1 were 0.74 Bq/L for 89Sr, and 1.47 Bq/L for 90Sr, detected by Cherenkov counting, 36–38 h after separation, and 30 min counting time.",
journal = "Talanta",
title = "Novel approach for strontium preconcentration from seawater and rapid determination of 89,90Sr in emergency situations",
volume = "250",
pages = "123722",
doi = "10.1016/j.talanta.2022.123722"
}
Coha, I., Smičiklas, I., Tucaković, I., Jović, M., Šljivić-Ivanović, M.,& Grahek, Ž.. (2022). Novel approach for strontium preconcentration from seawater and rapid determination of 89,90Sr in emergency situations. in Talanta, 250, 123722.
https://doi.org/10.1016/j.talanta.2022.123722
Coha I, Smičiklas I, Tucaković I, Jović M, Šljivić-Ivanović M, Grahek Ž. Novel approach for strontium preconcentration from seawater and rapid determination of 89,90Sr in emergency situations. in Talanta. 2022;250:123722.
doi:10.1016/j.talanta.2022.123722 .
Coha, Ivana, Smičiklas, Ivana, Tucaković, Ivana, Jović, Mihajlo, Šljivić-Ivanović, Marija, Grahek, Željko, "Novel approach for strontium preconcentration from seawater and rapid determination of 89,90Sr in emergency situations" in Talanta, 250 (2022):123722,
https://doi.org/10.1016/j.talanta.2022.123722 . .

Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle

Prodanović, Radiša; Kirovski, Danijela; Vujanac, Ivan; Đorđević, Ana; Romić, Snježana Đ.; Pantelić, Marija; Korićanac, Goran

(2022)

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
AU  - Đorđević, Ana
AU  - Romić, Snježana Đ.
AU  - Pantelić, Marija
AU  - Korićanac, Goran
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10356
AB  - A number of alterations have been identified in lipid metabolism within adipose tissue and liver in obesity. Less is known about the capacity of skeletal muscle for the metabolism of fatty acids in obesity-related insulin resistance, though it is evident that dry cow muscles may contain increased triglyceride content. The current study was therefore undertaken to evaluate the skeletal muscle expression of proteins of the fatty acid metabolism in dry cows with different body condition scores (BCS). Sixteen Holstein-Friesian close-up cows were divided into 2 equal groups based on their BCS as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Blood samples collection and skeletal muscle biopsies were carried out at day 10 before calving. Blood serum was assayed for concentration of resistin using a bovine specific ELISA. Protein expression of insulin receptor beta subunit (IRβ), glucose transporter 4 (GLUT4), fatty acid translocase (FAT/CD36), fatty acid transporter 1 (FATP1), carnitine palmitoyltransferase 1 (CPT1), AMP-acitvated protein kinase (AMPK) and lipin 1 were analyzed in semitendinosus muscle by immunoblot. Resistin differed non-significantly between high-BCS and optimal-BCS cows. Insulin-resistant lipid metabolism in obese cows was paralleled with increased skeletal muscle expression of lipin 1 and GLUT4, and decreased expression of IRβ and FATP1. These data suggest that in obesity-related insulin resistance, metabolic capacity in dry cow skeletal muscles appears to be organized towards the synthesis of signaling intermediates rather than fatty acids oxidation and that altered fatty acid uptake does not contribute to this disposition.
T2  - Research in Veterinary Science
T1  - Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle
VL  - 150
SP  - 189
EP  - 194
DO  - 10.1016/j.rvsc.2022.04.012
ER  - 
@article{
author = "Prodanović, Radiša and Kirovski, Danijela and Vujanac, Ivan and Đorđević, Ana and Romić, Snježana Đ. and Pantelić, Marija and Korićanac, Goran",
year = "2022",
abstract = "A number of alterations have been identified in lipid metabolism within adipose tissue and liver in obesity. Less is known about the capacity of skeletal muscle for the metabolism of fatty acids in obesity-related insulin resistance, though it is evident that dry cow muscles may contain increased triglyceride content. The current study was therefore undertaken to evaluate the skeletal muscle expression of proteins of the fatty acid metabolism in dry cows with different body condition scores (BCS). Sixteen Holstein-Friesian close-up cows were divided into 2 equal groups based on their BCS as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Blood samples collection and skeletal muscle biopsies were carried out at day 10 before calving. Blood serum was assayed for concentration of resistin using a bovine specific ELISA. Protein expression of insulin receptor beta subunit (IRβ), glucose transporter 4 (GLUT4), fatty acid translocase (FAT/CD36), fatty acid transporter 1 (FATP1), carnitine palmitoyltransferase 1 (CPT1), AMP-acitvated protein kinase (AMPK) and lipin 1 were analyzed in semitendinosus muscle by immunoblot. Resistin differed non-significantly between high-BCS and optimal-BCS cows. Insulin-resistant lipid metabolism in obese cows was paralleled with increased skeletal muscle expression of lipin 1 and GLUT4, and decreased expression of IRβ and FATP1. These data suggest that in obesity-related insulin resistance, metabolic capacity in dry cow skeletal muscles appears to be organized towards the synthesis of signaling intermediates rather than fatty acids oxidation and that altered fatty acid uptake does not contribute to this disposition.",
journal = "Research in Veterinary Science",
title = "Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle",
volume = "150",
pages = "189-194",
doi = "10.1016/j.rvsc.2022.04.012"
}
Prodanović, R., Kirovski, D., Vujanac, I., Đorđević, A., Romić, S. Đ., Pantelić, M.,& Korićanac, G.. (2022). Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle. in Research in Veterinary Science, 150, 189-194.
https://doi.org/10.1016/j.rvsc.2022.04.012
Prodanović R, Kirovski D, Vujanac I, Đorđević A, Romić SĐ, Pantelić M, Korićanac G. Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle. in Research in Veterinary Science. 2022;150:189-194.
doi:10.1016/j.rvsc.2022.04.012 .
Prodanović, Radiša, Kirovski, Danijela, Vujanac, Ivan, Đorđević, Ana, Romić, Snježana Đ., Pantelić, Marija, Korićanac, Goran, "Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle" in Research in Veterinary Science, 150 (2022):189-194,
https://doi.org/10.1016/j.rvsc.2022.04.012 . .

Mechanical Properties of Biomass-derived Silica Nanoparticles Reinforced PMMA Composite Material

Vuksanović, Marija M.; Mladenović, Ivana O.; Tomić, Nataša Z.; Petrović, Miloš; Radojević, Vesna J.; Marinković, Aleksandar D.; Heinemann-Jančić, Radmila M.

(2022)

TY  - JOUR
AU  - Vuksanović, Marija M.
AU  - Mladenović, Ivana O.
AU  - Tomić, Nataša Z.
AU  - Petrović, Miloš
AU  - Radojević, Vesna J.
AU  - Marinković, Aleksandar D.
AU  - Heinemann-Jančić, Radmila M.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10340
AB  - Rice husk was used to produce silica particles, which were then used to reinforce the polymer matrix. The synthesized SiO2 particles were characterized using X-ray diffraction, Fourier transforms infrared spectroscopy (FTIR) and scanning electron microscopy with EDS. In a PMMA matrix, prepared SiO2 particles in amounts of 1, 3, and 5 wt.% were used as reinforcing agents. The goal of this research was to see if SiO2 particles had any effect on the mechanical properties of polymer composite materials. The morphology of the composites was examined using a field emission scanning electron microscope (FE-SEM). Vickers microindentation hardness and impact testing were used to determine the mechanical properties of the obtained composites. The indentation creep’s behavior of a polymethylmetacrylate (PMMA) composite material with varying amounts of nanoparticles (SiO2) was investigated and analyzed.
T2  - Science of Sintering
T1  - Mechanical Properties of Biomass-derived Silica Nanoparticles Reinforced PMMA Composite Material
VL  - 54
IS  - 2
DO  - 10.2298/SOS2202211V
ER  - 
@article{
author = "Vuksanović, Marija M. and Mladenović, Ivana O. and Tomić, Nataša Z. and Petrović, Miloš and Radojević, Vesna J. and Marinković, Aleksandar D. and Heinemann-Jančić, Radmila M.",
year = "2022",
abstract = "Rice husk was used to produce silica particles, which were then used to reinforce the polymer matrix. The synthesized SiO2 particles were characterized using X-ray diffraction, Fourier transforms infrared spectroscopy (FTIR) and scanning electron microscopy with EDS. In a PMMA matrix, prepared SiO2 particles in amounts of 1, 3, and 5 wt.% were used as reinforcing agents. The goal of this research was to see if SiO2 particles had any effect on the mechanical properties of polymer composite materials. The morphology of the composites was examined using a field emission scanning electron microscope (FE-SEM). Vickers microindentation hardness and impact testing were used to determine the mechanical properties of the obtained composites. The indentation creep’s behavior of a polymethylmetacrylate (PMMA) composite material with varying amounts of nanoparticles (SiO2) was investigated and analyzed.",
journal = "Science of Sintering",
title = "Mechanical Properties of Biomass-derived Silica Nanoparticles Reinforced PMMA Composite Material",
volume = "54",
number = "2",
doi = "10.2298/SOS2202211V"
}
Vuksanović, M. M., Mladenović, I. O., Tomić, N. Z., Petrović, M., Radojević, V. J., Marinković, A. D.,& Heinemann-Jančić, R. M.. (2022). Mechanical Properties of Biomass-derived Silica Nanoparticles Reinforced PMMA Composite Material. in Science of Sintering, 54(2).
https://doi.org/10.2298/SOS2202211V
Vuksanović MM, Mladenović IO, Tomić NZ, Petrović M, Radojević VJ, Marinković AD, Heinemann-Jančić RM. Mechanical Properties of Biomass-derived Silica Nanoparticles Reinforced PMMA Composite Material. in Science of Sintering. 2022;54(2).
doi:10.2298/SOS2202211V .
Vuksanović, Marija M., Mladenović, Ivana O., Tomić, Nataša Z., Petrović, Miloš, Radojević, Vesna J., Marinković, Aleksandar D., Heinemann-Jančić, Radmila M., "Mechanical Properties of Biomass-derived Silica Nanoparticles Reinforced PMMA Composite Material" in Science of Sintering, 54, no. 2 (2022),
https://doi.org/10.2298/SOS2202211V . .

Fast, eco-friendly synthesis of blue luminescent nitrogen-doped graphene quantum dots in glycerol

Trpkov, Đorđe; Vinić, Milica; Dojčilović, Radovan; Tošić, Dragana

(2022)

TY  - JOUR
AU  - Trpkov, Đorđe
AU  - Vinić, Milica
AU  - Dojčilović, Radovan
AU  - Tošić, Dragana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10347
AB  - Nitrogen-functionalized graphene quantum dots (N-GQDs) were synthesized by hydrothermal transformation of glycine precursors in glycerol. Functionalization of GQDs with nitrogen was confirmed with FTIR spectroscopy. Atomic force microscopy (AFM) analysis revealed that the thickness of the quantum dots is around similar to 1 nm while the lateral dimensions are in the range from 20 to 80 nm. N-GQDs exhibit strong fluorescence in the blue (420 nm) region and they are suitable for bioimaging applications.
T2  - Optical and Quantum Electronics
T1  - Fast, eco-friendly synthesis of blue luminescent nitrogen-doped graphene quantum dots in glycerol
VL  - 54
IS  - 6
SP  - 387
DO  - 10.1007/s11082-022-03754-0
ER  - 
@article{
author = "Trpkov, Đorđe and Vinić, Milica and Dojčilović, Radovan and Tošić, Dragana",
year = "2022",
abstract = "Nitrogen-functionalized graphene quantum dots (N-GQDs) were synthesized by hydrothermal transformation of glycine precursors in glycerol. Functionalization of GQDs with nitrogen was confirmed with FTIR spectroscopy. Atomic force microscopy (AFM) analysis revealed that the thickness of the quantum dots is around similar to 1 nm while the lateral dimensions are in the range from 20 to 80 nm. N-GQDs exhibit strong fluorescence in the blue (420 nm) region and they are suitable for bioimaging applications.",
journal = "Optical and Quantum Electronics",
title = "Fast, eco-friendly synthesis of blue luminescent nitrogen-doped graphene quantum dots in glycerol",
volume = "54",
number = "6",
pages = "387",
doi = "10.1007/s11082-022-03754-0"
}
Trpkov, Đ., Vinić, M., Dojčilović, R.,& Tošić, D.. (2022). Fast, eco-friendly synthesis of blue luminescent nitrogen-doped graphene quantum dots in glycerol. in Optical and Quantum Electronics, 54(6), 387.
https://doi.org/10.1007/s11082-022-03754-0
Trpkov Đ, Vinić M, Dojčilović R, Tošić D. Fast, eco-friendly synthesis of blue luminescent nitrogen-doped graphene quantum dots in glycerol. in Optical and Quantum Electronics. 2022;54(6):387.
doi:10.1007/s11082-022-03754-0 .
Trpkov, Đorđe, Vinić, Milica, Dojčilović, Radovan, Tošić, Dragana, "Fast, eco-friendly synthesis of blue luminescent nitrogen-doped graphene quantum dots in glycerol" in Optical and Quantum Electronics, 54, no. 6 (2022):387,
https://doi.org/10.1007/s11082-022-03754-0 . .

Biochemical changes in cancer cells induced by photoactive nanosystem based on carbon dots loaded with Ru-complex

Nešić, Maja D.; Dučić, Tanja; Gonçalves, Mara; Stepić, Milutin; Algarra, Manuel; Soto, Juan; Gemović, Branislava S.; Bandosz, Teresa J.; Petković, Marijana

(2022)

TY  - JOUR
AU  - Nešić, Maja D.
AU  - Dučić, Tanja
AU  - Gonçalves, Mara
AU  - Stepić, Milutin
AU  - Algarra, Manuel
AU  - Soto, Juan
AU  - Gemović, Branislava S.
AU  - Bandosz, Teresa J.
AU  - Petković, Marijana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10267
AB  - Carbon dots (CDs) and N-carbon dots (N-CDs) loaded with Ru-complex (CDs@RuCN, N-CDs@RuCN, respectively) were investigated as media imposing biochemical changes induced by UV illumination of ovarian cancer, A2780, and osteosarcoma, CAL72, cells. Synchrotron radiation-based Fourier Transform Infrared Spectroscopy was performed, and the spectra were subjected to a Principal Component Analysis. The CDs@RuCN and N-CDs@RuCN effects on cancer cells were analyzed by the theoretical modelling of the stability of the composite systems and a protein database search. Moreover, a detailed evaluation of surface and optical properties of CDs@RuCN and N-CDs@RuCN was carried out. Results demonstrated selective action of the CDs@RuCN and N-CDs@RuCN-based photodynamic therapy, with N-CDs@RuCN being the most active in inducing changes in A2780 and CDs@RuCN in CAL72 cells. We assume that different surface charges of nanoparticles led to direct interactions of N-CDs@RuCN with a Wnt signalling pathway in A2780 and those of CDs@RuCN with PI3–K/Akt in CAL72 cells and that further biochemical changes occurred upon light illumination.
T2  - Chemico-Biological Interactions
T1  - Biochemical changes in cancer cells induced by photoactive nanosystem based on carbon dots loaded with Ru-complex
VL  - 360
SP  - 109950
DO  - 10.1016/j.cbi.2022.109950
ER  - 
@article{
author = "Nešić, Maja D. and Dučić, Tanja and Gonçalves, Mara and Stepić, Milutin and Algarra, Manuel and Soto, Juan and Gemović, Branislava S. and Bandosz, Teresa J. and Petković, Marijana",
year = "2022",
abstract = "Carbon dots (CDs) and N-carbon dots (N-CDs) loaded with Ru-complex (CDs@RuCN, N-CDs@RuCN, respectively) were investigated as media imposing biochemical changes induced by UV illumination of ovarian cancer, A2780, and osteosarcoma, CAL72, cells. Synchrotron radiation-based Fourier Transform Infrared Spectroscopy was performed, and the spectra were subjected to a Principal Component Analysis. The CDs@RuCN and N-CDs@RuCN effects on cancer cells were analyzed by the theoretical modelling of the stability of the composite systems and a protein database search. Moreover, a detailed evaluation of surface and optical properties of CDs@RuCN and N-CDs@RuCN was carried out. Results demonstrated selective action of the CDs@RuCN and N-CDs@RuCN-based photodynamic therapy, with N-CDs@RuCN being the most active in inducing changes in A2780 and CDs@RuCN in CAL72 cells. We assume that different surface charges of nanoparticles led to direct interactions of N-CDs@RuCN with a Wnt signalling pathway in A2780 and those of CDs@RuCN with PI3–K/Akt in CAL72 cells and that further biochemical changes occurred upon light illumination.",
journal = "Chemico-Biological Interactions",
title = "Biochemical changes in cancer cells induced by photoactive nanosystem based on carbon dots loaded with Ru-complex",
volume = "360",
pages = "109950",
doi = "10.1016/j.cbi.2022.109950"
}
Nešić, M. D., Dučić, T., Gonçalves, M., Stepić, M., Algarra, M., Soto, J., Gemović, B. S., Bandosz, T. J.,& Petković, M.. (2022). Biochemical changes in cancer cells induced by photoactive nanosystem based on carbon dots loaded with Ru-complex. in Chemico-Biological Interactions, 360, 109950.
https://doi.org/10.1016/j.cbi.2022.109950
Nešić MD, Dučić T, Gonçalves M, Stepić M, Algarra M, Soto J, Gemović BS, Bandosz TJ, Petković M. Biochemical changes in cancer cells induced by photoactive nanosystem based on carbon dots loaded with Ru-complex. in Chemico-Biological Interactions. 2022;360:109950.
doi:10.1016/j.cbi.2022.109950 .
Nešić, Maja D., Dučić, Tanja, Gonçalves, Mara, Stepić, Milutin, Algarra, Manuel, Soto, Juan, Gemović, Branislava S., Bandosz, Teresa J., Petković, Marijana, "Biochemical changes in cancer cells induced by photoactive nanosystem based on carbon dots loaded with Ru-complex" in Chemico-Biological Interactions, 360 (2022):109950,
https://doi.org/10.1016/j.cbi.2022.109950 . .
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