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Recycled Poly(ethylene Terephthalate) Based-Plasticizer for PVC Regranulates Production

Čutović, Natalija; Vuksanović, Marija M.; Milošević, Milena; Bugarčić, Mladen; Bošnjaković, Jovana; Gržetić, Jelena; Marinković, Aleksandar

TY  - CONF
AU  - Čutović, Natalija
AU  - Vuksanović, Marija M.
AU  - Milošević, Milena
AU  - Bugarčić, Mladen
AU  - Bošnjaković, Jovana
AU  - Gržetić, Jelena
AU  - Marinković, Aleksandar
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10674
AB  - Due to the increasing use and widespread of plastics, poly (ethylene terephthalate) (PET) and poly (vinyl chloride) (PVC) are becoming one of the major threats to the environment. The aim of this paper is obtaining plasticizers from recycled PET, and hot/cold mixing thereof with PVC to produce new materials. Plasticizer was obtained from PET using ethylene glycol (EG) in the presence of catalyst FASCAT 4100, followed by treatment with maleic anhydride and finally 2-ethylhexanol (2-EtHex). The obtained glycolysate and plasticizer, individually or mixtures thereof, were used for the production of polygranulates based on waste PVC in order to obtain an expanded mass of homogenized PVC with glycolysate/plasticizer. The abovementioned procedures and test results for the regranulates and products indicate that the proposed technology offers a solution to the problem of waste PET and PVC through transesterification in order to obtain plasticizer based on PET and EG, called 2-EtHex/MA/РG/PET/EG/MA/2-EtHex used in the processing of PVC waste and in regranulate. The obtained regranulates are further processed by injection molding or extrusion into commercial products such as slippers, footwear, boots, garden hoses, mats, floor mats, etc.
PB  - University of Belgrade, Technical Faculty in Bor
C3  - 29th International Conference Ecological Truth and Environmental Research – EcoTER’22" Sokobanja, June 21-24, 2022
T1  - Recycled Poly(ethylene Terephthalate) Based-Plasticizer for PVC Regranulates Production
SP  - 452
EP  - 458
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10674
ER  - 
@conference{
author = "Čutović, Natalija and Vuksanović, Marija M. and Milošević, Milena and Bugarčić, Mladen and Bošnjaković, Jovana and Gržetić, Jelena and Marinković, Aleksandar",
abstract = "Due to the increasing use and widespread of plastics, poly (ethylene terephthalate) (PET) and poly (vinyl chloride) (PVC) are becoming one of the major threats to the environment. The aim of this paper is obtaining plasticizers from recycled PET, and hot/cold mixing thereof with PVC to produce new materials. Plasticizer was obtained from PET using ethylene glycol (EG) in the presence of catalyst FASCAT 4100, followed by treatment with maleic anhydride and finally 2-ethylhexanol (2-EtHex). The obtained glycolysate and plasticizer, individually or mixtures thereof, were used for the production of polygranulates based on waste PVC in order to obtain an expanded mass of homogenized PVC with glycolysate/plasticizer. The abovementioned procedures and test results for the regranulates and products indicate that the proposed technology offers a solution to the problem of waste PET and PVC through transesterification in order to obtain plasticizer based on PET and EG, called 2-EtHex/MA/РG/PET/EG/MA/2-EtHex used in the processing of PVC waste and in regranulate. The obtained regranulates are further processed by injection molding or extrusion into commercial products such as slippers, footwear, boots, garden hoses, mats, floor mats, etc.",
publisher = "University of Belgrade, Technical Faculty in Bor",
journal = "29th International Conference Ecological Truth and Environmental Research – EcoTER’22" Sokobanja, June 21-24, 2022",
title = "Recycled Poly(ethylene Terephthalate) Based-Plasticizer for PVC Regranulates Production",
pages = "452-458",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10674"
}
Čutović, N., Vuksanović, M. M., Milošević, M., Bugarčić, M., Bošnjaković, J., Gržetić, J.,& Marinković, A..Recycled Poly(ethylene Terephthalate) Based-Plasticizer for PVC Regranulates Production. in 29th International Conference Ecological Truth and Environmental Research – EcoTER’22" Sokobanja, June 21-24, 2022
University of Belgrade, Technical Faculty in Bor., 452-458.
https://hdl.handle.net/21.15107/rcub_vinar_10674
Čutović N, Vuksanović MM, Milošević M, Bugarčić M, Bošnjaković J, Gržetić J, Marinković A. Recycled Poly(ethylene Terephthalate) Based-Plasticizer for PVC Regranulates Production. in 29th International Conference Ecological Truth and Environmental Research – EcoTER’22" Sokobanja, June 21-24, 2022.:452-458.
https://hdl.handle.net/21.15107/rcub_vinar_10674 .
Čutović, Natalija, Vuksanović, Marija M., Milošević, Milena, Bugarčić, Mladen, Bošnjaković, Jovana, Gržetić, Jelena, Marinković, Aleksandar, "Recycled Poly(ethylene Terephthalate) Based-Plasticizer for PVC Regranulates Production" in 29th International Conference Ecological Truth and Environmental Research – EcoTER’22" Sokobanja, June 21-24, 2022:452-458,
https://hdl.handle.net/21.15107/rcub_vinar_10674 .

Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA

Sakata, Dousatsu; Hirayama, Ryoichi; Shin, Wook-Geun; Belli, Mauro; Tabocchini, Maria A; Stewart, Robert D; Belov, Oleg; Bernal, Mario A; Bordage, Marie-Claude; Brown, Jeremy M.C.; Đorđević, Miloš; Emfietzoglou, Dimitris; Francis, Ziad; Guatelli, Susanna; Inaniwa, Taku; Ivanchenko, Vladimir; Karamitros, Mathieu; Kyriakou, Ioanna; Lampe, Nathanael; Li, Zhuxin; Meylan, Sylvain; Michelet, Claire; Nieminen, Petteri; Perrot, Yann; Petrović, Ivan M.; Ramos-Mendez, Jose; Ristić-Fira, Aleksandra; Santin, Giovanni; Schuemann, Jan; Tran, Hoang N; Villagrasa, Carmen; Incerti, Sebastien

(2023)

TY  - JOUR
AU  - Sakata, Dousatsu
AU  - Hirayama, Ryoichi
AU  - Shin, Wook-Geun
AU  - Belli, Mauro
AU  - Tabocchini, Maria A
AU  - Stewart, Robert D
AU  - Belov, Oleg
AU  - Bernal, Mario A
AU  - Bordage, Marie-Claude
AU  - Brown, Jeremy M.C.
AU  - Đorđević, Miloš
AU  - Emfietzoglou, Dimitris
AU  - Francis, Ziad
AU  - Guatelli, Susanna
AU  - Inaniwa, Taku
AU  - Ivanchenko, Vladimir
AU  - Karamitros, Mathieu
AU  - Kyriakou, Ioanna
AU  - Lampe, Nathanael
AU  - Li, Zhuxin
AU  - Meylan, Sylvain
AU  - Michelet, Claire
AU  - Nieminen, Petteri
AU  - Perrot, Yann
AU  - Petrović, Ivan M.
AU  - Ramos-Mendez, Jose
AU  - Ristić-Fira, Aleksandra
AU  - Santin, Giovanni
AU  - Schuemann, Jan
AU  - Tran, Hoang N
AU  - Villagrasa, Carmen
AU  - Incerti, Sebastien
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10573
AB  - Purpose: Track structure Monte Carlo (MC) codes have achieved successful outcomes in the quantitative investigation of radiation-induced initial DNA damage. The aim of the present study is to extend a Geant4-DNA radiobiological application by incorporating a feature allowing for the prediction of DNA rejoining kinetics and corresponding cell surviving fraction along time after irradiation, for a Chinese hamster V79 cell line, which is one of the most popular and widely investigated cell lines in radiobiology. Methods: We implemented the Two-Lesion Kinetics (TLK) model, originally proposed by Stewart, which allows for simulations to calculate residual DNA damage and surviving fraction along time via the number of initial DNA damage and its complexity as inputs. Results: By optimizing the model parameters of the TLK model in accordance to the experimental data on V79, we were able to predict both DNA rejoining kinetics at low linear energy transfers (LET) and cell surviving fraction. Conclusion: This is the first study to demonstrate the implementation of both the cell surviving fraction and the DNA rejoining kinetics with the estimated initial DNA damage, in a realistic cell geometrical model simulated by full track structure MC simulations at DNA level and for various LET. These simulation and model make the link between mechanistic physical/chemical damage processes and these two specific biological endpoints.
T2  - Physica Medica
T1  - Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA
VL  - 105
SP  - 102508
DO  - 10.1016/j.ejmp.2022.11.012
ER  - 
@article{
author = "Sakata, Dousatsu and Hirayama, Ryoichi and Shin, Wook-Geun and Belli, Mauro and Tabocchini, Maria A and Stewart, Robert D and Belov, Oleg and Bernal, Mario A and Bordage, Marie-Claude and Brown, Jeremy M.C. and Đorđević, Miloš and Emfietzoglou, Dimitris and Francis, Ziad and Guatelli, Susanna and Inaniwa, Taku and Ivanchenko, Vladimir and Karamitros, Mathieu and Kyriakou, Ioanna and Lampe, Nathanael and Li, Zhuxin and Meylan, Sylvain and Michelet, Claire and Nieminen, Petteri and Perrot, Yann and Petrović, Ivan M. and Ramos-Mendez, Jose and Ristić-Fira, Aleksandra and Santin, Giovanni and Schuemann, Jan and Tran, Hoang N and Villagrasa, Carmen and Incerti, Sebastien",
year = "2023",
abstract = "Purpose: Track structure Monte Carlo (MC) codes have achieved successful outcomes in the quantitative investigation of radiation-induced initial DNA damage. The aim of the present study is to extend a Geant4-DNA radiobiological application by incorporating a feature allowing for the prediction of DNA rejoining kinetics and corresponding cell surviving fraction along time after irradiation, for a Chinese hamster V79 cell line, which is one of the most popular and widely investigated cell lines in radiobiology. Methods: We implemented the Two-Lesion Kinetics (TLK) model, originally proposed by Stewart, which allows for simulations to calculate residual DNA damage and surviving fraction along time via the number of initial DNA damage and its complexity as inputs. Results: By optimizing the model parameters of the TLK model in accordance to the experimental data on V79, we were able to predict both DNA rejoining kinetics at low linear energy transfers (LET) and cell surviving fraction. Conclusion: This is the first study to demonstrate the implementation of both the cell surviving fraction and the DNA rejoining kinetics with the estimated initial DNA damage, in a realistic cell geometrical model simulated by full track structure MC simulations at DNA level and for various LET. These simulation and model make the link between mechanistic physical/chemical damage processes and these two specific biological endpoints.",
journal = "Physica Medica",
title = "Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA",
volume = "105",
pages = "102508",
doi = "10.1016/j.ejmp.2022.11.012"
}
Sakata, D., Hirayama, R., Shin, W., Belli, M., Tabocchini, M. A., Stewart, R. D., Belov, O., Bernal, M. A., Bordage, M., Brown, J. M.C., Đorđević, M., Emfietzoglou, D., Francis, Z., Guatelli, S., Inaniwa, T., Ivanchenko, V., Karamitros, M., Kyriakou, I., Lampe, N., Li, Z., Meylan, S., Michelet, C., Nieminen, P., Perrot, Y., Petrović, I. M., Ramos-Mendez, J., Ristić-Fira, A., Santin, G., Schuemann, J., Tran, H. N., Villagrasa, C.,& Incerti, S.. (2023). Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA. in Physica Medica, 105, 102508.
https://doi.org/10.1016/j.ejmp.2022.11.012
Sakata D, Hirayama R, Shin W, Belli M, Tabocchini MA, Stewart RD, Belov O, Bernal MA, Bordage M, Brown JM, Đorđević M, Emfietzoglou D, Francis Z, Guatelli S, Inaniwa T, Ivanchenko V, Karamitros M, Kyriakou I, Lampe N, Li Z, Meylan S, Michelet C, Nieminen P, Perrot Y, Petrović IM, Ramos-Mendez J, Ristić-Fira A, Santin G, Schuemann J, Tran HN, Villagrasa C, Incerti S. Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA. in Physica Medica. 2023;105:102508.
doi:10.1016/j.ejmp.2022.11.012 .
Sakata, Dousatsu, Hirayama, Ryoichi, Shin, Wook-Geun, Belli, Mauro, Tabocchini, Maria A, Stewart, Robert D, Belov, Oleg, Bernal, Mario A, Bordage, Marie-Claude, Brown, Jeremy M.C., Đorđević, Miloš, Emfietzoglou, Dimitris, Francis, Ziad, Guatelli, Susanna, Inaniwa, Taku, Ivanchenko, Vladimir, Karamitros, Mathieu, Kyriakou, Ioanna, Lampe, Nathanael, Li, Zhuxin, Meylan, Sylvain, Michelet, Claire, Nieminen, Petteri, Perrot, Yann, Petrović, Ivan M., Ramos-Mendez, Jose, Ristić-Fira, Aleksandra, Santin, Giovanni, Schuemann, Jan, Tran, Hoang N, Villagrasa, Carmen, Incerti, Sebastien, "Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA" in Physica Medica, 105 (2023):102508,
https://doi.org/10.1016/j.ejmp.2022.11.012 . .
1

Simulation of DNA damage using Geant4-DNA: an overview of the “molecularDNA” example application

Chatzipapas, Konstantinos P.; Tran, Ngoc Hoang; Đorđević, Miloš; Živković, Sara; Zein, Sara; Shin, Wook-Geun; Sakata, Dousatsu; Lampe, Nathanael; Brown, Jeremy M. C.; Ristić-Fira, Aleksandra; Petrović, Ivan M.; Kyriakou, Ioanna; Emfietzoglou, Dimitris; Guatelli, Susanna; Incerti, Sebastien

(2023)

TY  - JOUR
AU  - Chatzipapas, Konstantinos P.
AU  - Tran, Ngoc Hoang
AU  - Đorđević, Miloš
AU  - Živković, Sara
AU  - Zein, Sara
AU  - Shin, Wook-Geun
AU  - Sakata, Dousatsu
AU  - Lampe, Nathanael
AU  - Brown, Jeremy M. C.
AU  - Ristić-Fira, Aleksandra
AU  - Petrović, Ivan M.
AU  - Kyriakou, Ioanna
AU  - Emfietzoglou, Dimitris
AU  - Guatelli, Susanna
AU  - Incerti, Sebastien
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10661
AB  - Purpose The scientific community shows great interest in the study of DNA damage induction, DNA damage repair, and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4-DNA example application, named “molecularDNA”, publicly released in the 11.1 version of Geant4 (December 2022). Methods It was developed for novice Geant4 users and requires only a basic understanding of scripting languages to get started. The example includes two different DNA-scale geometries of biological targets, namely “cylinders” and “human cell”. This public version is based on a previous prototype and includes new features, such as: the adoption of a new approach for the modeling of the chemical stage, the use of the standard DNA damage format to describe radiation-induced DNA damage, and upgraded computational tools to estimate DNA damage response. Results Simulation data in terms of single-strand break and double-strand break yields were produced using each of the available geometries. The results were compared with the literature, to validate the example, producing less than 5% difference in all cases. Conclusion: “molecularDNA” is a prototype tool that can be applied in a wide variety of radiobiology studies, providing the scientific community with an open-access base for DNA damage quantification calculations. New DNA and cell geometries for the “molecularDNA” example will be included in future versions of Geant4-DNA.
T2  - Precision Radiation Oncology
T1  - Simulation of DNA damage using Geant4-DNA: an overview of the “molecularDNA” example application
IS  - InPress
DO  - 10.1002/pro6.1186
ER  - 
@article{
author = "Chatzipapas, Konstantinos P. and Tran, Ngoc Hoang and Đorđević, Miloš and Živković, Sara and Zein, Sara and Shin, Wook-Geun and Sakata, Dousatsu and Lampe, Nathanael and Brown, Jeremy M. C. and Ristić-Fira, Aleksandra and Petrović, Ivan M. and Kyriakou, Ioanna and Emfietzoglou, Dimitris and Guatelli, Susanna and Incerti, Sebastien",
year = "2023",
abstract = "Purpose The scientific community shows great interest in the study of DNA damage induction, DNA damage repair, and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4-DNA example application, named “molecularDNA”, publicly released in the 11.1 version of Geant4 (December 2022). Methods It was developed for novice Geant4 users and requires only a basic understanding of scripting languages to get started. The example includes two different DNA-scale geometries of biological targets, namely “cylinders” and “human cell”. This public version is based on a previous prototype and includes new features, such as: the adoption of a new approach for the modeling of the chemical stage, the use of the standard DNA damage format to describe radiation-induced DNA damage, and upgraded computational tools to estimate DNA damage response. Results Simulation data in terms of single-strand break and double-strand break yields were produced using each of the available geometries. The results were compared with the literature, to validate the example, producing less than 5% difference in all cases. Conclusion: “molecularDNA” is a prototype tool that can be applied in a wide variety of radiobiology studies, providing the scientific community with an open-access base for DNA damage quantification calculations. New DNA and cell geometries for the “molecularDNA” example will be included in future versions of Geant4-DNA.",
journal = "Precision Radiation Oncology",
title = "Simulation of DNA damage using Geant4-DNA: an overview of the “molecularDNA” example application",
number = "InPress",
doi = "10.1002/pro6.1186"
}
Chatzipapas, K. P., Tran, N. H., Đorđević, M., Živković, S., Zein, S., Shin, W., Sakata, D., Lampe, N., Brown, J. M. C., Ristić-Fira, A., Petrović, I. M., Kyriakou, I., Emfietzoglou, D., Guatelli, S.,& Incerti, S.. (2023). Simulation of DNA damage using Geant4-DNA: an overview of the “molecularDNA” example application. in Precision Radiation Oncology(InPress).
https://doi.org/10.1002/pro6.1186
Chatzipapas KP, Tran NH, Đorđević M, Živković S, Zein S, Shin W, Sakata D, Lampe N, Brown JMC, Ristić-Fira A, Petrović IM, Kyriakou I, Emfietzoglou D, Guatelli S, Incerti S. Simulation of DNA damage using Geant4-DNA: an overview of the “molecularDNA” example application. in Precision Radiation Oncology. 2023;(InPress).
doi:10.1002/pro6.1186 .
Chatzipapas, Konstantinos P., Tran, Ngoc Hoang, Đorđević, Miloš, Živković, Sara, Zein, Sara, Shin, Wook-Geun, Sakata, Dousatsu, Lampe, Nathanael, Brown, Jeremy M. C., Ristić-Fira, Aleksandra, Petrović, Ivan M., Kyriakou, Ioanna, Emfietzoglou, Dimitris, Guatelli, Susanna, Incerti, Sebastien, "Simulation of DNA damage using Geant4-DNA: an overview of the “molecularDNA” example application" in Precision Radiation Oncology, no. InPress (2023),
https://doi.org/10.1002/pro6.1186 . .

Monte Carlo simulation of health risk from cadmium, lead, and nickel in cigarettes

Lučić, Milica; Momčilović, Milan Z.; Marković, Jelena; Jović, Mihajlo D.; Smičiklas, Ivana D.; Onjia, Antonije E.

(2023)

TY  - JOUR
AU  - Lučić, Milica
AU  - Momčilović, Milan Z.
AU  - Marković, Jelena
AU  - Jović, Mihajlo D.
AU  - Smičiklas, Ivana D.
AU  - Onjia, Antonije E.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10695
AB  - The human health risks of cadmium (Cd), lead (Pb), and nickel (Ni) in fifty regular and slim cigarette brands available in the Serbian market were evaluated. Distributions on per-cigarette basis concentrations of these metals, as determined by graphite furnace atomic absorption spectrometry, were used as inputs in the probabilistic risk assessment. The contents of these metals in cigarettes varied significantly. Larger quantities of the studied metals were observed in regular cigarettes than in slim cigarettes, but the concentration levels per cigarette tobacco mass were higher in slim cigarettes. The metal concentrations in counterfeit cigarettes were marginally higher than those in authentic brands. Based on the mean concentrations, Pb was the most abundant toxic metal, followed by Ni and Cd. The calculated values of the cumulative hazard index (HI) and incremental lifetime cancer risk (ILCR) indicated a low noncarcinogenic risk and low but not negligible carcinogenic risk from Cd, Pb, and Ni. The mean HI and ILCR values obtained using probabilistic and deterministic approaches were similar. A Monte Carlo simulation was employed to minimize the uncertainty of health risk estimation. The sensitivity analysis revealed that the most influential factor was cigarette mass followed by Cd content.
T2  - Toxicological & Environmental Chemistry
T1  - Monte Carlo simulation of health risk from cadmium, lead, and nickel in cigarettes
IS  - inPress
SP  - 1
EP  - 19
DO  - 10.1080/02772248.2023.2177291
ER  - 
@article{
author = "Lučić, Milica and Momčilović, Milan Z. and Marković, Jelena and Jović, Mihajlo D. and Smičiklas, Ivana D. and Onjia, Antonije E.",
year = "2023",
abstract = "The human health risks of cadmium (Cd), lead (Pb), and nickel (Ni) in fifty regular and slim cigarette brands available in the Serbian market were evaluated. Distributions on per-cigarette basis concentrations of these metals, as determined by graphite furnace atomic absorption spectrometry, were used as inputs in the probabilistic risk assessment. The contents of these metals in cigarettes varied significantly. Larger quantities of the studied metals were observed in regular cigarettes than in slim cigarettes, but the concentration levels per cigarette tobacco mass were higher in slim cigarettes. The metal concentrations in counterfeit cigarettes were marginally higher than those in authentic brands. Based on the mean concentrations, Pb was the most abundant toxic metal, followed by Ni and Cd. The calculated values of the cumulative hazard index (HI) and incremental lifetime cancer risk (ILCR) indicated a low noncarcinogenic risk and low but not negligible carcinogenic risk from Cd, Pb, and Ni. The mean HI and ILCR values obtained using probabilistic and deterministic approaches were similar. A Monte Carlo simulation was employed to minimize the uncertainty of health risk estimation. The sensitivity analysis revealed that the most influential factor was cigarette mass followed by Cd content.",
journal = "Toxicological & Environmental Chemistry",
title = "Monte Carlo simulation of health risk from cadmium, lead, and nickel in cigarettes",
number = "inPress",
pages = "1-19",
doi = "10.1080/02772248.2023.2177291"
}
Lučić, M., Momčilović, M. Z., Marković, J., Jović, M. D., Smičiklas, I. D.,& Onjia, A. E.. (2023). Monte Carlo simulation of health risk from cadmium, lead, and nickel in cigarettes. in Toxicological & Environmental Chemistry(inPress), 1-19.
https://doi.org/10.1080/02772248.2023.2177291
Lučić M, Momčilović MZ, Marković J, Jović MD, Smičiklas ID, Onjia AE. Monte Carlo simulation of health risk from cadmium, lead, and nickel in cigarettes. in Toxicological & Environmental Chemistry. 2023;(inPress):1-19.
doi:10.1080/02772248.2023.2177291 .
Lučić, Milica, Momčilović, Milan Z., Marković, Jelena, Jović, Mihajlo D., Smičiklas, Ivana D., Onjia, Antonije E., "Monte Carlo simulation of health risk from cadmium, lead, and nickel in cigarettes" in Toxicological & Environmental Chemistry, no. inPress (2023):1-19,
https://doi.org/10.1080/02772248.2023.2177291 . .

Antimicrobial and UV protective chitosan/lignin multilayer nanocoating with immobilized silver nanoparticles

Marković, Darka; Petkovska, Jovana; Mladenović, Nina; Radoičić, Marija B.; Rodriguez-Melendez, Danixa; Ilić-Tomić, Tatjana; Radetić, Maja; Grunlan, Jaime; Jordanov, Igor

(2023)

TY  - JOUR
AU  - Marković, Darka
AU  - Petkovska, Jovana
AU  - Mladenović, Nina
AU  - Radoičić, Marija B.
AU  - Rodriguez-Melendez, Danixa
AU  - Ilić-Tomić, Tatjana
AU  - Radetić, Maja
AU  - Grunlan, Jaime
AU  - Jordanov, Igor
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10753
AB  - Poor antimicrobial activity and lack of protection against UV irradiation are weaknesses of cottontextiles. In an attempt to impart superior antimicrobial and UV-protective properties to cotton, layer-by-layer deposition of chitosan and magnesium lignosulfonate, and in situ synthesis of silver (Ag)nanoparticles (NPs), was performed. Lignin, in a chitosan/lignin multilayer, simultaneously acts as a UVprotective macromolecule and natural reducing and stabilizing agent, allowing formation of Ag NPs. Fourbilayers of this coating is sufficient for fabrication of a chitosan/lignin/Ag-NP textile nanocompositetreatment with 50+ UV protection. 100% reduction of Gram-negative bacteria Escherichia coli, gram-positive bacteria Staphylococcus aureus, and yeast Candida albicans can be achieved with a 12-bilayercoating, when 20 mM silver nitrate solution and sodium borohydride are applied. On the other hand,four bilayers impregnated with Ag NPs, using 10 mM silver nitrate solution, provides sufficientantimicrobial activity independent of an added reducing agent. This treatment exhibits no inhibition ofhuman keratinocyte cells growth on the skin, indicating low cytotoxicity.
T2  - Journal of Applied Polymer Science
T1  - Antimicrobial and UV protective chitosan/lignin multilayer nanocoating with immobilized silver nanoparticles
IS  - InPress
DO  - 10.1002/app.53823
ER  - 
@article{
author = "Marković, Darka and Petkovska, Jovana and Mladenović, Nina and Radoičić, Marija B. and Rodriguez-Melendez, Danixa and Ilić-Tomić, Tatjana and Radetić, Maja and Grunlan, Jaime and Jordanov, Igor",
year = "2023",
abstract = "Poor antimicrobial activity and lack of protection against UV irradiation are weaknesses of cottontextiles. In an attempt to impart superior antimicrobial and UV-protective properties to cotton, layer-by-layer deposition of chitosan and magnesium lignosulfonate, and in situ synthesis of silver (Ag)nanoparticles (NPs), was performed. Lignin, in a chitosan/lignin multilayer, simultaneously acts as a UVprotective macromolecule and natural reducing and stabilizing agent, allowing formation of Ag NPs. Fourbilayers of this coating is sufficient for fabrication of a chitosan/lignin/Ag-NP textile nanocompositetreatment with 50+ UV protection. 100% reduction of Gram-negative bacteria Escherichia coli, gram-positive bacteria Staphylococcus aureus, and yeast Candida albicans can be achieved with a 12-bilayercoating, when 20 mM silver nitrate solution and sodium borohydride are applied. On the other hand,four bilayers impregnated with Ag NPs, using 10 mM silver nitrate solution, provides sufficientantimicrobial activity independent of an added reducing agent. This treatment exhibits no inhibition ofhuman keratinocyte cells growth on the skin, indicating low cytotoxicity.",
journal = "Journal of Applied Polymer Science",
title = "Antimicrobial and UV protective chitosan/lignin multilayer nanocoating with immobilized silver nanoparticles",
number = "InPress",
doi = "10.1002/app.53823"
}
Marković, D., Petkovska, J., Mladenović, N., Radoičić, M. B., Rodriguez-Melendez, D., Ilić-Tomić, T., Radetić, M., Grunlan, J.,& Jordanov, I.. (2023). Antimicrobial and UV protective chitosan/lignin multilayer nanocoating with immobilized silver nanoparticles. in Journal of Applied Polymer Science(InPress).
https://doi.org/10.1002/app.53823
Marković D, Petkovska J, Mladenović N, Radoičić MB, Rodriguez-Melendez D, Ilić-Tomić T, Radetić M, Grunlan J, Jordanov I. Antimicrobial and UV protective chitosan/lignin multilayer nanocoating with immobilized silver nanoparticles. in Journal of Applied Polymer Science. 2023;(InPress).
doi:10.1002/app.53823 .
Marković, Darka, Petkovska, Jovana, Mladenović, Nina, Radoičić, Marija B., Rodriguez-Melendez, Danixa, Ilić-Tomić, Tatjana, Radetić, Maja, Grunlan, Jaime, Jordanov, Igor, "Antimicrobial and UV protective chitosan/lignin multilayer nanocoating with immobilized silver nanoparticles" in Journal of Applied Polymer Science, no. InPress (2023),
https://doi.org/10.1002/app.53823 . .

Charge self-trapping in two strand biomolecules: Adiabatic polaron approach

Čevizović, Dalibor; Zdravković, Slobodan; Chizhov, Alexei V.; Ivić, Zoran

(2023)

TY  - JOUR
AU  - Čevizović, Dalibor
AU  - Zdravković, Slobodan
AU  - Chizhov, Alexei V.
AU  - Ivić, Zoran
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10752
AB  - We investigate the properties of the excess charge (electron, hole) introduced into a two-strand biomolecule. We consider the possibility that the stable soliton excitation can be formed due to interaction of excess charge with the phonon subsystem. The influence of overlap of the molecular orbitals between adjacent structure elements of the macromolecular chain on the soliton properties is discussed. Special attention is paid to the influence of the overlapping of the molecular orbitals between structure elements placed on the different chains. Using the literature values of the basic energy parameters of the two-chain biomolecular structures, possible types of soliton solutions are discussed. © 2023 Chinese Physical Society and IOP Publishing Ltd.
T2  - Chinese Physics B
T1  - Charge self-trapping in two strand biomolecules: Adiabatic polaron approach
VL  - 32
IS  - 1
SP  - 010506
DO  - 10.1088/1674-1056/ac70bc
ER  - 
@article{
author = "Čevizović, Dalibor and Zdravković, Slobodan and Chizhov, Alexei V. and Ivić, Zoran",
year = "2023",
abstract = "We investigate the properties of the excess charge (electron, hole) introduced into a two-strand biomolecule. We consider the possibility that the stable soliton excitation can be formed due to interaction of excess charge with the phonon subsystem. The influence of overlap of the molecular orbitals between adjacent structure elements of the macromolecular chain on the soliton properties is discussed. Special attention is paid to the influence of the overlapping of the molecular orbitals between structure elements placed on the different chains. Using the literature values of the basic energy parameters of the two-chain biomolecular structures, possible types of soliton solutions are discussed. © 2023 Chinese Physical Society and IOP Publishing Ltd.",
journal = "Chinese Physics B",
title = "Charge self-trapping in two strand biomolecules: Adiabatic polaron approach",
volume = "32",
number = "1",
pages = "010506",
doi = "10.1088/1674-1056/ac70bc"
}
Čevizović, D., Zdravković, S., Chizhov, A. V.,& Ivić, Z.. (2023). Charge self-trapping in two strand biomolecules: Adiabatic polaron approach. in Chinese Physics B, 32(1), 010506.
https://doi.org/10.1088/1674-1056/ac70bc
Čevizović D, Zdravković S, Chizhov AV, Ivić Z. Charge self-trapping in two strand biomolecules: Adiabatic polaron approach. in Chinese Physics B. 2023;32(1):010506.
doi:10.1088/1674-1056/ac70bc .
Čevizović, Dalibor, Zdravković, Slobodan, Chizhov, Alexei V., Ivić, Zoran, "Charge self-trapping in two strand biomolecules: Adiabatic polaron approach" in Chinese Physics B, 32, no. 1 (2023):010506,
https://doi.org/10.1088/1674-1056/ac70bc . .
1

How Well Do Our Adsorbents Actually Perform?—The Case of Dimethoate Removal Using Viscose Fiber-Derived Carbons

Anićijević, Vladan J.; Tasić, Tamara; Milanković, Vedran; Breitenbach, Stefan; Unterweger, Christoph; Fürst, Christian; Bajuk-Bogdanović, Danica; Pašti, Igor A.; Lazarević-Pašti, Tamara

(2023)

TY  - JOUR
AU  - Anićijević, Vladan J.
AU  - Tasić, Tamara
AU  - Milanković, Vedran
AU  - Breitenbach, Stefan
AU  - Unterweger, Christoph
AU  - Fürst, Christian
AU  - Bajuk-Bogdanović, Danica
AU  - Pašti, Igor A.
AU  - Lazarević-Pašti, Tamara
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10751
AB  - Growing pollution is making it necessary to find new strategies and materials for the removal of undesired compounds from the environment. Adsorption is still one of the simplest and most efficient routes for the remediation of air, soil, and water. However, the choice of adsorbent for a given application ultimately depends on its performance assessment results. Here, we show that the uptake of and capacity for dimethoate adsorption by different viscose-derived (activated) carbons strongly depend on the adsorbent dose applied in the adsorption measurements. The specific surface areas of the investigated materials varied across a wide range from 264 m2 g−1 to 2833 m2 g−1. For a dimethoate concentration of 5 × 10−4 mol L−1 and a high adsorbent dose of 10 mg mL−1, the adsorption capacities were all below 15 mg g−1. In the case of high-surface-area activated carbons, the uptakes were almost 100% under identical conditions. However, when the adsorbent dose was reduced to 0.01 mg mL−1, uptake was significantly reduced, but adsorption capacities as high as 1280 mg g−1 were obtained. Further, adsorption capacities were linked to adsorbents’ physical and chemical properties (specific surface area, pore size distribution, chemical composition), and thermodynamic parameters for the adsorption process were evaluated. Based on the Gibbs free energy of the adsorption process, it can be suggested that physisorption was operative for all studied adsorbents. Finally, we suggest that a proper comparison of different adsorbents requires standardization of the protocols used to evaluate pollutant uptakes and adsorption capacities.
T2  - International Journal of Environmental Research and Public Health
T1  - How Well Do Our Adsorbents Actually Perform?—The Case of Dimethoate Removal Using Viscose Fiber-Derived Carbons
VL  - 20
IS  - 5
SP  - 4553
DO  - 10.3390/ijerph20054553
ER  - 
@article{
author = "Anićijević, Vladan J. and Tasić, Tamara and Milanković, Vedran and Breitenbach, Stefan and Unterweger, Christoph and Fürst, Christian and Bajuk-Bogdanović, Danica and Pašti, Igor A. and Lazarević-Pašti, Tamara",
year = "2023",
abstract = "Growing pollution is making it necessary to find new strategies and materials for the removal of undesired compounds from the environment. Adsorption is still one of the simplest and most efficient routes for the remediation of air, soil, and water. However, the choice of adsorbent for a given application ultimately depends on its performance assessment results. Here, we show that the uptake of and capacity for dimethoate adsorption by different viscose-derived (activated) carbons strongly depend on the adsorbent dose applied in the adsorption measurements. The specific surface areas of the investigated materials varied across a wide range from 264 m2 g−1 to 2833 m2 g−1. For a dimethoate concentration of 5 × 10−4 mol L−1 and a high adsorbent dose of 10 mg mL−1, the adsorption capacities were all below 15 mg g−1. In the case of high-surface-area activated carbons, the uptakes were almost 100% under identical conditions. However, when the adsorbent dose was reduced to 0.01 mg mL−1, uptake was significantly reduced, but adsorption capacities as high as 1280 mg g−1 were obtained. Further, adsorption capacities were linked to adsorbents’ physical and chemical properties (specific surface area, pore size distribution, chemical composition), and thermodynamic parameters for the adsorption process were evaluated. Based on the Gibbs free energy of the adsorption process, it can be suggested that physisorption was operative for all studied adsorbents. Finally, we suggest that a proper comparison of different adsorbents requires standardization of the protocols used to evaluate pollutant uptakes and adsorption capacities.",
journal = "International Journal of Environmental Research and Public Health",
title = "How Well Do Our Adsorbents Actually Perform?—The Case of Dimethoate Removal Using Viscose Fiber-Derived Carbons",
volume = "20",
number = "5",
pages = "4553",
doi = "10.3390/ijerph20054553"
}
Anićijević, V. J., Tasić, T., Milanković, V., Breitenbach, S., Unterweger, C., Fürst, C., Bajuk-Bogdanović, D., Pašti, I. A.,& Lazarević-Pašti, T.. (2023). How Well Do Our Adsorbents Actually Perform?—The Case of Dimethoate Removal Using Viscose Fiber-Derived Carbons. in International Journal of Environmental Research and Public Health, 20(5), 4553.
https://doi.org/10.3390/ijerph20054553
Anićijević VJ, Tasić T, Milanković V, Breitenbach S, Unterweger C, Fürst C, Bajuk-Bogdanović D, Pašti IA, Lazarević-Pašti T. How Well Do Our Adsorbents Actually Perform?—The Case of Dimethoate Removal Using Viscose Fiber-Derived Carbons. in International Journal of Environmental Research and Public Health. 2023;20(5):4553.
doi:10.3390/ijerph20054553 .
Anićijević, Vladan J., Tasić, Tamara, Milanković, Vedran, Breitenbach, Stefan, Unterweger, Christoph, Fürst, Christian, Bajuk-Bogdanović, Danica, Pašti, Igor A., Lazarević-Pašti, Tamara, "How Well Do Our Adsorbents Actually Perform?—The Case of Dimethoate Removal Using Viscose Fiber-Derived Carbons" in International Journal of Environmental Research and Public Health, 20, no. 5 (2023):4553,
https://doi.org/10.3390/ijerph20054553 . .

Amorphous non-doped and Se-, Cu-, and Zn-doped Sb2S3 nanoparticles prepared by a hot-injection method: bandgap tuning and possible observation of the quantum size effect

Validžić, Ivana Lj.; Popović, Maja; Potočnik, Jelena; Graf, Christina; Joschko, Maximilian; Kuznetsova, Yulia A.; Zatsepin, Dmitry A.

(2023)

TY  - JOUR
AU  - Validžić, Ivana Lj.
AU  - Popović, Maja
AU  - Potočnik, Jelena
AU  - Graf, Christina
AU  - Joschko, Maximilian
AU  - Kuznetsova, Yulia A.
AU  - Zatsepin, Dmitry A.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10750
AB  - Amorphous, non-doped, and copper- and selenium-doped Sb2S3 nanoparticles were synthesized by a hot-injection method. Zinc-doped Sb2S3 nanoparticles were prepared for the first time using the same approach. Electron microscopy revealed that spherical nanoparticles of 1–4 nanometers aggregated into larger spherical clusters. Introducing dopants into the Sb2S3 structure neither influenced the samples’ spherical morphology nor their sizes. The presence of the dopants (Cu, Se, or Zn) was confirmed by energy dispersive X-ray (EDX) and, in the case of Zn, also by inductively coupled plasma-mass spectrometry (ICP-MS). The X-ray powder diffraction (XRPD) patterns of the non-doped and doped samples imply an amorphous structure. Crystalline Zn-doped Sb2S3 revealed defined peaks from only the Sb2S3 phase, indicating successful doping. Diffuse reflectance spectroscopy (DRS) revealed high optical bandgap energies (2.03–2.12 eV) compared to the values (1.6–1.7 eV) for large non-doped and doped particles obtained at 240 °C, which might be attributed to a quantum size effect. X-ray photoelectron spectroscopy (XPS) revealed a phase without any impurities for the undoped and characteristic peaks for copper, selenium, and zinc Auger for the doped samples. XPS valence band confirm for the Zn-doped particles a shift towards lower binding energy compared to the non-doped samples, indicating successful doping. Photoluminescence (PL) measurements show that embedding Zn into the Sb2S3 host lattice suppresses the wide luminescence band related to intrinsic vacancy defects. Narrow peaks at 1.7–2.4 eV were found to be associated with singlet excitons. The energy dependence of the light emission on the synthesized nanoparticles’ size suggests quantum confinement. © 2023, The Author(s), under exclusive licence to Springer Nature B.V.
T2  - Journal of Nanoparticle Research
T1  - Amorphous non-doped and Se-, Cu-, and Zn-doped Sb2S3 nanoparticles prepared by a hot-injection method: bandgap tuning and possible observation of the quantum size effect
VL  - 25
IS  - 3
SP  - 48
DO  - 10.1007/s11051-023-05695-5
ER  - 
@article{
author = "Validžić, Ivana Lj. and Popović, Maja and Potočnik, Jelena and Graf, Christina and Joschko, Maximilian and Kuznetsova, Yulia A. and Zatsepin, Dmitry A.",
year = "2023",
abstract = "Amorphous, non-doped, and copper- and selenium-doped Sb2S3 nanoparticles were synthesized by a hot-injection method. Zinc-doped Sb2S3 nanoparticles were prepared for the first time using the same approach. Electron microscopy revealed that spherical nanoparticles of 1–4 nanometers aggregated into larger spherical clusters. Introducing dopants into the Sb2S3 structure neither influenced the samples’ spherical morphology nor their sizes. The presence of the dopants (Cu, Se, or Zn) was confirmed by energy dispersive X-ray (EDX) and, in the case of Zn, also by inductively coupled plasma-mass spectrometry (ICP-MS). The X-ray powder diffraction (XRPD) patterns of the non-doped and doped samples imply an amorphous structure. Crystalline Zn-doped Sb2S3 revealed defined peaks from only the Sb2S3 phase, indicating successful doping. Diffuse reflectance spectroscopy (DRS) revealed high optical bandgap energies (2.03–2.12 eV) compared to the values (1.6–1.7 eV) for large non-doped and doped particles obtained at 240 °C, which might be attributed to a quantum size effect. X-ray photoelectron spectroscopy (XPS) revealed a phase without any impurities for the undoped and characteristic peaks for copper, selenium, and zinc Auger for the doped samples. XPS valence band confirm for the Zn-doped particles a shift towards lower binding energy compared to the non-doped samples, indicating successful doping. Photoluminescence (PL) measurements show that embedding Zn into the Sb2S3 host lattice suppresses the wide luminescence band related to intrinsic vacancy defects. Narrow peaks at 1.7–2.4 eV were found to be associated with singlet excitons. The energy dependence of the light emission on the synthesized nanoparticles’ size suggests quantum confinement. © 2023, The Author(s), under exclusive licence to Springer Nature B.V.",
journal = "Journal of Nanoparticle Research",
title = "Amorphous non-doped and Se-, Cu-, and Zn-doped Sb2S3 nanoparticles prepared by a hot-injection method: bandgap tuning and possible observation of the quantum size effect",
volume = "25",
number = "3",
pages = "48",
doi = "10.1007/s11051-023-05695-5"
}
Validžić, I. Lj., Popović, M., Potočnik, J., Graf, C., Joschko, M., Kuznetsova, Y. A.,& Zatsepin, D. A.. (2023). Amorphous non-doped and Se-, Cu-, and Zn-doped Sb2S3 nanoparticles prepared by a hot-injection method: bandgap tuning and possible observation of the quantum size effect. in Journal of Nanoparticle Research, 25(3), 48.
https://doi.org/10.1007/s11051-023-05695-5
Validžić IL, Popović M, Potočnik J, Graf C, Joschko M, Kuznetsova YA, Zatsepin DA. Amorphous non-doped and Se-, Cu-, and Zn-doped Sb2S3 nanoparticles prepared by a hot-injection method: bandgap tuning and possible observation of the quantum size effect. in Journal of Nanoparticle Research. 2023;25(3):48.
doi:10.1007/s11051-023-05695-5 .
Validžić, Ivana Lj., Popović, Maja, Potočnik, Jelena, Graf, Christina, Joschko, Maximilian, Kuznetsova, Yulia A., Zatsepin, Dmitry A., "Amorphous non-doped and Se-, Cu-, and Zn-doped Sb2S3 nanoparticles prepared by a hot-injection method: bandgap tuning and possible observation of the quantum size effect" in Journal of Nanoparticle Research, 25, no. 3 (2023):48,
https://doi.org/10.1007/s11051-023-05695-5 . .

Socio-Economic Analysis of the Construction and Building Materials’ Usage—Ecological Awareness in the Case of Serbia

Vidak-Vasić, Milica; Goel, Gaurav; Dubale, Mandefrot; Živković, Slavica; Trivunić, Milan; Pezo, Milada L.; Pezo, Lato

(2023)

TY  - JOUR
AU  - Vidak-Vasić, Milica
AU  - Goel, Gaurav
AU  - Dubale, Mandefrot
AU  - Živković, Slavica
AU  - Trivunić, Milan
AU  - Pezo, Milada L.
AU  - Pezo, Lato
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10749
AB  - The main idea of the present study was to investigate the impact of the ongoing world crisis on the socio-economic issues in Serbia concerning building materials usage and purchase. This research fills in the gaps in the literature and contributes to the comprehension of how the crisis has affected salaries, market pricing, and materials consumption in the building sector. The data are gathered through a questionnaire and analyzed using a statistical methodology (frequencies, descriptive statistics, and Spearman’s correlations). Most of the former studies investigated the surveys conducted on specialists in the field, while this study analyzed the perspectives of random people. Socio-demographic issues are analyzed along with materials consumption before and after the crisis. A special emphasis is given to ecological awareness and novel materials usage. Additionally, it captures a broad shift in the economy and ecological consciousness in a developing country. The majority of respondents are open to using novel building materials and products, but their choice would largely be influenced by cost, the amount of effort involved, and their understanding of the advantages. Statistical approaches revealed that the crisis has a considerable impact on the markets for construction and building supplies, altering consumers’ decisions when purchasing. This contribution lays the groundwork for developing countries in the modern world to improve sustainability and adopt circular thinking. Professionals in Serbia need to have a more eco-aware mindset and enhance how they provide pertinent information to potential clients. This study is limited by the number of respondents. For future mathematical modeling and forecasting, more answerers are needed.
T2  - Sustainability
T1  - Socio-Economic Analysis of the Construction and Building Materials’ Usage—Ecological Awareness in the Case of Serbia
VL  - 15
IS  - 5
SP  - 4080
DO  - 10.3390/su15054080
ER  - 
@article{
author = "Vidak-Vasić, Milica and Goel, Gaurav and Dubale, Mandefrot and Živković, Slavica and Trivunić, Milan and Pezo, Milada L. and Pezo, Lato",
year = "2023",
abstract = "The main idea of the present study was to investigate the impact of the ongoing world crisis on the socio-economic issues in Serbia concerning building materials usage and purchase. This research fills in the gaps in the literature and contributes to the comprehension of how the crisis has affected salaries, market pricing, and materials consumption in the building sector. The data are gathered through a questionnaire and analyzed using a statistical methodology (frequencies, descriptive statistics, and Spearman’s correlations). Most of the former studies investigated the surveys conducted on specialists in the field, while this study analyzed the perspectives of random people. Socio-demographic issues are analyzed along with materials consumption before and after the crisis. A special emphasis is given to ecological awareness and novel materials usage. Additionally, it captures a broad shift in the economy and ecological consciousness in a developing country. The majority of respondents are open to using novel building materials and products, but their choice would largely be influenced by cost, the amount of effort involved, and their understanding of the advantages. Statistical approaches revealed that the crisis has a considerable impact on the markets for construction and building supplies, altering consumers’ decisions when purchasing. This contribution lays the groundwork for developing countries in the modern world to improve sustainability and adopt circular thinking. Professionals in Serbia need to have a more eco-aware mindset and enhance how they provide pertinent information to potential clients. This study is limited by the number of respondents. For future mathematical modeling and forecasting, more answerers are needed.",
journal = "Sustainability",
title = "Socio-Economic Analysis of the Construction and Building Materials’ Usage—Ecological Awareness in the Case of Serbia",
volume = "15",
number = "5",
pages = "4080",
doi = "10.3390/su15054080"
}
Vidak-Vasić, M., Goel, G., Dubale, M., Živković, S., Trivunić, M., Pezo, M. L.,& Pezo, L.. (2023). Socio-Economic Analysis of the Construction and Building Materials’ Usage—Ecological Awareness in the Case of Serbia. in Sustainability, 15(5), 4080.
https://doi.org/10.3390/su15054080
Vidak-Vasić M, Goel G, Dubale M, Živković S, Trivunić M, Pezo ML, Pezo L. Socio-Economic Analysis of the Construction and Building Materials’ Usage—Ecological Awareness in the Case of Serbia. in Sustainability. 2023;15(5):4080.
doi:10.3390/su15054080 .
Vidak-Vasić, Milica, Goel, Gaurav, Dubale, Mandefrot, Živković, Slavica, Trivunić, Milan, Pezo, Milada L., Pezo, Lato, "Socio-Economic Analysis of the Construction and Building Materials’ Usage—Ecological Awareness in the Case of Serbia" in Sustainability, 15, no. 5 (2023):4080,
https://doi.org/10.3390/su15054080 . .

Structure-dependent optical properties of Au/Ag irradiated TiN thin films

Popović, Maja; Novaković, Mirjana M.; Vaňa, Dušan; Ronning, Carsten; Jugović, Dragana; Rajić, Vladimir; Noga, Pavol

(2023)

TY  - JOUR
AU  - Popović, Maja
AU  - Novaković, Mirjana M.
AU  - Vaňa, Dušan
AU  - Ronning, Carsten
AU  - Jugović, Dragana
AU  - Rajić, Vladimir
AU  - Noga, Pavol
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10746
AB  - Titanium nitride (TiN) is an attractive alternative for modern and future photonic applications, as its optical properties can be engineered over a wide spectral range. In this study, we have used sequential implantation of gold and silver ions with varying ion fluence, as well as subsequent annealing, in order to modify the optical and plasmonic properties of TiN thin films and correlated this to their structural properties. Our investigations show that the columnar structure of the TiN films is partially destroyed upon implantation, but metallic Au and Ag nanoparticles are formed. The irradiation further induces a reduction of the lattice constant as well as changes the TiN stoichiometry and grain size. From the optical point of view, the implanted films possess less metallicity with increasing Ag fluence and losses several times lower than the as-deposited film, which can be correlated with the deficiency of nitrogen and additional defects. Subsequent annealing partially recovered the destroyed columnar structure, and the films become more metallic where the optical losses are much smaller in comparison to the as-implanted situation, being comparable to those of pure Au and Ag. In this way, by varying the implantation fluence of silver ions properly while keeping the gold fluence constant, we were able to optimize experimental parameters in such a way to ensure the formation of TiN with desirable optical performances.
T2  - Optical Materials
T1  - Structure-dependent optical properties of Au/Ag irradiated TiN thin films
VL  - 138
SP  - 113684
DO  - 10.1016/j.optmat.2023.113684
UR  - https://hdl.handle.net/21.15107/rcub_dais_14289
ER  - 
@article{
author = "Popović, Maja and Novaković, Mirjana M. and Vaňa, Dušan and Ronning, Carsten and Jugović, Dragana and Rajić, Vladimir and Noga, Pavol",
year = "2023",
abstract = "Titanium nitride (TiN) is an attractive alternative for modern and future photonic applications, as its optical properties can be engineered over a wide spectral range. In this study, we have used sequential implantation of gold and silver ions with varying ion fluence, as well as subsequent annealing, in order to modify the optical and plasmonic properties of TiN thin films and correlated this to their structural properties. Our investigations show that the columnar structure of the TiN films is partially destroyed upon implantation, but metallic Au and Ag nanoparticles are formed. The irradiation further induces a reduction of the lattice constant as well as changes the TiN stoichiometry and grain size. From the optical point of view, the implanted films possess less metallicity with increasing Ag fluence and losses several times lower than the as-deposited film, which can be correlated with the deficiency of nitrogen and additional defects. Subsequent annealing partially recovered the destroyed columnar structure, and the films become more metallic where the optical losses are much smaller in comparison to the as-implanted situation, being comparable to those of pure Au and Ag. In this way, by varying the implantation fluence of silver ions properly while keeping the gold fluence constant, we were able to optimize experimental parameters in such a way to ensure the formation of TiN with desirable optical performances.",
journal = "Optical Materials",
title = "Structure-dependent optical properties of Au/Ag irradiated TiN thin films",
volume = "138",
pages = "113684",
doi = "10.1016/j.optmat.2023.113684",
url = "https://hdl.handle.net/21.15107/rcub_dais_14289"
}
Popović, M., Novaković, M. M., Vaňa, D., Ronning, C., Jugović, D., Rajić, V.,& Noga, P.. (2023). Structure-dependent optical properties of Au/Ag irradiated TiN thin films. in Optical Materials, 138, 113684.
https://doi.org/10.1016/j.optmat.2023.113684
https://hdl.handle.net/21.15107/rcub_dais_14289
Popović M, Novaković MM, Vaňa D, Ronning C, Jugović D, Rajić V, Noga P. Structure-dependent optical properties of Au/Ag irradiated TiN thin films. in Optical Materials. 2023;138:113684.
doi:10.1016/j.optmat.2023.113684
https://hdl.handle.net/21.15107/rcub_dais_14289 .
Popović, Maja, Novaković, Mirjana M., Vaňa, Dušan, Ronning, Carsten, Jugović, Dragana, Rajić, Vladimir, Noga, Pavol, "Structure-dependent optical properties of Au/Ag irradiated TiN thin films" in Optical Materials, 138 (2023):113684,
https://doi.org/10.1016/j.optmat.2023.113684 .,
https://hdl.handle.net/21.15107/rcub_dais_14289 .

The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain

Todorović, Jasna; Dinčić, Marko; Krstić, Danijela Z.; Čolović, Mirjana B.; Nešović-Ostojić, Jelena; Kovačević, Sanjin; Lopičić, Srđan; Spasić, Svetolik; Brkić, Predrag; Milovanović, Aleksandar

(2023)

TY  - JOUR
AU  - Todorović, Jasna
AU  - Dinčić, Marko
AU  - Krstić, Danijela Z.
AU  - Čolović, Mirjana B.
AU  - Nešović-Ostojić, Jelena
AU  - Kovačević, Sanjin
AU  - Lopičić, Srđan
AU  - Spasić, Svetolik
AU  - Brkić, Predrag
AU  - Milovanović, Aleksandar
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10745
AB  - Background: Thyroid dysfunctions as well as sleep abnormalities are usually followed by neurological, psychiatric and/or behavioral disorders. On the other hand, changes in the brain adenosine triphosphatases (ATPases) and acetylcholinesterase (AChE) activities show significant importance in pathogenetic pathways in the evolution of numerous neuropsychiatric diseases. Methods: This study aimed to evaluate the in vivo simultaneous effects of hypothyroidism and paradoxical sleep deprivation for 72 h on synaptosomalATPases and AChE activities of whole rat brains. In order to induce hypothyroidism, 6-n-propyl-2-thiouracil was administrated in drinking water during 21 days. The modified multiple platform method was used to induce paradoxical sleep deprivation. The AChE and ATPases activities were measured using spectrophotometric methods. Results: Hypothyroidism significantly increased the activity of Na+/K+-ATPase compared to other groups, while at the same time significantly decreased AChE activity compared to the CT and SD groups. Paradoxical sleep deprivation significantly increased AChE activity compared to other groups. The simultaneous effect of hypothyroidism and sleep deprivation reduced the activity of all three enzymes (for Na+/K+-ATPase between HT/SD and HT group p < 0.0001, SD group p < 0.001,CT group p = 0.013; for ecto-ATPases between HT/SD and HT group p = 0.0034, SD group p = 0.0001, CT group p = 0.0007; for AChE between HT/SD and HT group p < 0.05, SD group p < 0.0001, CT group p < 0.0001). Conclusions: The effect of simultaneous existence of hypothyroidism and paradoxical sleep deprivation reduces the activity of the Na+/K+-ATPase, ecto-ATPases, and AChE, what is different from individual effect of hypothyroidism and paradoxical sleep deprivation itself. This knowledge could help in the choice of appropriate therapy in such condition. © 2023 Elsevier B.V.
T2  - Sleep Medicine
T1  - The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain
VL  - 105
SP  - 14
EP  - 20
DO  - 10.1016/j.sleep.2023.03.002
ER  - 
@article{
author = "Todorović, Jasna and Dinčić, Marko and Krstić, Danijela Z. and Čolović, Mirjana B. and Nešović-Ostojić, Jelena and Kovačević, Sanjin and Lopičić, Srđan and Spasić, Svetolik and Brkić, Predrag and Milovanović, Aleksandar",
year = "2023",
abstract = "Background: Thyroid dysfunctions as well as sleep abnormalities are usually followed by neurological, psychiatric and/or behavioral disorders. On the other hand, changes in the brain adenosine triphosphatases (ATPases) and acetylcholinesterase (AChE) activities show significant importance in pathogenetic pathways in the evolution of numerous neuropsychiatric diseases. Methods: This study aimed to evaluate the in vivo simultaneous effects of hypothyroidism and paradoxical sleep deprivation for 72 h on synaptosomalATPases and AChE activities of whole rat brains. In order to induce hypothyroidism, 6-n-propyl-2-thiouracil was administrated in drinking water during 21 days. The modified multiple platform method was used to induce paradoxical sleep deprivation. The AChE and ATPases activities were measured using spectrophotometric methods. Results: Hypothyroidism significantly increased the activity of Na+/K+-ATPase compared to other groups, while at the same time significantly decreased AChE activity compared to the CT and SD groups. Paradoxical sleep deprivation significantly increased AChE activity compared to other groups. The simultaneous effect of hypothyroidism and sleep deprivation reduced the activity of all three enzymes (for Na+/K+-ATPase between HT/SD and HT group p < 0.0001, SD group p < 0.001,CT group p = 0.013; for ecto-ATPases between HT/SD and HT group p = 0.0034, SD group p = 0.0001, CT group p = 0.0007; for AChE between HT/SD and HT group p < 0.05, SD group p < 0.0001, CT group p < 0.0001). Conclusions: The effect of simultaneous existence of hypothyroidism and paradoxical sleep deprivation reduces the activity of the Na+/K+-ATPase, ecto-ATPases, and AChE, what is different from individual effect of hypothyroidism and paradoxical sleep deprivation itself. This knowledge could help in the choice of appropriate therapy in such condition. © 2023 Elsevier B.V.",
journal = "Sleep Medicine",
title = "The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain",
volume = "105",
pages = "14-20",
doi = "10.1016/j.sleep.2023.03.002"
}
Todorović, J., Dinčić, M., Krstić, D. Z., Čolović, M. B., Nešović-Ostojić, J., Kovačević, S., Lopičić, S., Spasić, S., Brkić, P.,& Milovanović, A.. (2023). The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain. in Sleep Medicine, 105, 14-20.
https://doi.org/10.1016/j.sleep.2023.03.002
Todorović J, Dinčić M, Krstić DZ, Čolović MB, Nešović-Ostojić J, Kovačević S, Lopičić S, Spasić S, Brkić P, Milovanović A. The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain. in Sleep Medicine. 2023;105:14-20.
doi:10.1016/j.sleep.2023.03.002 .
Todorović, Jasna, Dinčić, Marko, Krstić, Danijela Z., Čolović, Mirjana B., Nešović-Ostojić, Jelena, Kovačević, Sanjin, Lopičić, Srđan, Spasić, Svetolik, Brkić, Predrag, Milovanović, Aleksandar, "The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain" in Sleep Medicine, 105 (2023):14-20,
https://doi.org/10.1016/j.sleep.2023.03.002 . .

Does oestradiol treatment alleviate obesity-induced oxidative stress in the male liver?

Panić, Anastasija; Sudar-Milovanović, Emina; Stanimirović, Julijana; Obradović, Milan M.; Zafirović, Sonja; Soskić, Sanja S.; Isenović, Esma R.

(2023)

TY  - JOUR
AU  - Panić, Anastasija
AU  - Sudar-Milovanović, Emina
AU  - Stanimirović, Julijana
AU  - Obradović, Milan M.
AU  - Zafirović, Sonja
AU  - Soskić, Sanja S.
AU  - Isenović, Esma R.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10744
AB  - The liver is an organ in which many oxidative processes occur and represents an important target of oxidative stress (OxS). Under physiological conditions of normal mitochondrial homeostasis, hepatocytes effectively remove reactive oxygen species (ROS) by enabling metabolic adaptations and through the antioxidant defence system mechanisms. However, obesity-induced lipid accumulation in the hepatocytes causes significantly elevated production of ROS, reduces oxidative capacity, and increases oxidative stress (OxS). In men, compared with premenopausal women, the development of insulin resistance (IR) and non-alcoholic fatty liver disease (NAFLD) in obesity are more prevalent, where oestradiol (E2), the most potent female sex steroid, is proposed as the main culprit. Exogenous oestradiol (E2) administration exerts beneficial effects on antioxidant properties, restores total plasma antioxidant capacity and decreases biomarkers of OxS in ovariectomized animal models. Thus, we hypothesized that E2 treatment in states of obesity could have beneficial effects against OxS in the obese male's liver. We assumed that E2 could directly affect the level of OxS by increasing the level/activity of the AOS enzymes, particularly SOD1, SOD2, GPx, and CAT, in obese males' livers. In addition, we assumed that the level of malondialdehyde (MDA) and protein carbonyl content (PCC) in obese males' livers would be reduced after E2 treatment as a result of E2 inhibitory effect on lipid peroxidation and protein oxidation, respectively. To test our hypothesis, we used the liver of a high-fat (HF) diet-fed male Wistar rats as an animal model of obesity, treated with E2 intraperitoneally (40 μg/kg). Preliminary results from this study support our hypothesis that E2 increases liver protein expression of AOS enzymes: SOD1, GPx, and CAT, in control and HF male rats compared with their respective controls. The protein level of SOD2 and CAT activity was increased in HF treated with E2 compared with non-treated HF rats. Moreover, as we expected, E2 administration significantly decreased the MDA level in both E2-treated groups compared to their controls, while the PCC level was significantly decreased in HF treated group compared with untreated HF rats. In conclusion, the preliminary results we obtained in this study indicate that E2 administration can effectively inhibit the OxS-related processes in the liver in HF diet-induced obesity by increasing AOS enzymes levels and CAT activity, and also by decreasing levels of MDA and PCC. A consequence of our hypothesis is that treatment with E2 may be an innovative way to improve obesity-related liver disease prevention and healing. © 2023 Elsevier Ltd
T2  - Medical Hypotheses
T1  - Does oestradiol treatment alleviate obesity-induced oxidative stress in the male liver?
VL  - 174
SP  - 111049
DO  - 10.1016/j.mehy.2023.111049
ER  - 
@article{
author = "Panić, Anastasija and Sudar-Milovanović, Emina and Stanimirović, Julijana and Obradović, Milan M. and Zafirović, Sonja and Soskić, Sanja S. and Isenović, Esma R.",
year = "2023",
abstract = "The liver is an organ in which many oxidative processes occur and represents an important target of oxidative stress (OxS). Under physiological conditions of normal mitochondrial homeostasis, hepatocytes effectively remove reactive oxygen species (ROS) by enabling metabolic adaptations and through the antioxidant defence system mechanisms. However, obesity-induced lipid accumulation in the hepatocytes causes significantly elevated production of ROS, reduces oxidative capacity, and increases oxidative stress (OxS). In men, compared with premenopausal women, the development of insulin resistance (IR) and non-alcoholic fatty liver disease (NAFLD) in obesity are more prevalent, where oestradiol (E2), the most potent female sex steroid, is proposed as the main culprit. Exogenous oestradiol (E2) administration exerts beneficial effects on antioxidant properties, restores total plasma antioxidant capacity and decreases biomarkers of OxS in ovariectomized animal models. Thus, we hypothesized that E2 treatment in states of obesity could have beneficial effects against OxS in the obese male's liver. We assumed that E2 could directly affect the level of OxS by increasing the level/activity of the AOS enzymes, particularly SOD1, SOD2, GPx, and CAT, in obese males' livers. In addition, we assumed that the level of malondialdehyde (MDA) and protein carbonyl content (PCC) in obese males' livers would be reduced after E2 treatment as a result of E2 inhibitory effect on lipid peroxidation and protein oxidation, respectively. To test our hypothesis, we used the liver of a high-fat (HF) diet-fed male Wistar rats as an animal model of obesity, treated with E2 intraperitoneally (40 μg/kg). Preliminary results from this study support our hypothesis that E2 increases liver protein expression of AOS enzymes: SOD1, GPx, and CAT, in control and HF male rats compared with their respective controls. The protein level of SOD2 and CAT activity was increased in HF treated with E2 compared with non-treated HF rats. Moreover, as we expected, E2 administration significantly decreased the MDA level in both E2-treated groups compared to their controls, while the PCC level was significantly decreased in HF treated group compared with untreated HF rats. In conclusion, the preliminary results we obtained in this study indicate that E2 administration can effectively inhibit the OxS-related processes in the liver in HF diet-induced obesity by increasing AOS enzymes levels and CAT activity, and also by decreasing levels of MDA and PCC. A consequence of our hypothesis is that treatment with E2 may be an innovative way to improve obesity-related liver disease prevention and healing. © 2023 Elsevier Ltd",
journal = "Medical Hypotheses",
title = "Does oestradiol treatment alleviate obesity-induced oxidative stress in the male liver?",
volume = "174",
pages = "111049",
doi = "10.1016/j.mehy.2023.111049"
}
Panić, A., Sudar-Milovanović, E., Stanimirović, J., Obradović, M. M., Zafirović, S., Soskić, S. S.,& Isenović, E. R.. (2023). Does oestradiol treatment alleviate obesity-induced oxidative stress in the male liver?. in Medical Hypotheses, 174, 111049.
https://doi.org/10.1016/j.mehy.2023.111049
Panić A, Sudar-Milovanović E, Stanimirović J, Obradović MM, Zafirović S, Soskić SS, Isenović ER. Does oestradiol treatment alleviate obesity-induced oxidative stress in the male liver?. in Medical Hypotheses. 2023;174:111049.
doi:10.1016/j.mehy.2023.111049 .
Panić, Anastasija, Sudar-Milovanović, Emina, Stanimirović, Julijana, Obradović, Milan M., Zafirović, Sonja, Soskić, Sanja S., Isenović, Esma R., "Does oestradiol treatment alleviate obesity-induced oxidative stress in the male liver?" in Medical Hypotheses, 174 (2023):111049,
https://doi.org/10.1016/j.mehy.2023.111049 . .

High-density optical interconnects based on self-imaging in coupled waveguide arrays

Petrović, Jovana S.; Kršić, Jelena; Maluckov, Aleksandra; Veerman, J.J.P.

(2023)

TY  - JOUR
AU  - Petrović, Jovana S.
AU  - Kršić, Jelena
AU  - Maluckov, Aleksandra
AU  - Veerman, J.J.P.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10743
AB  - Rapidly increasing demand for higher data bandwidths has motivated exploration of new communication channels based on spatially multiplexed in-fibre and on-chip coupled light guides. However, the conventionally used periodically arranged coupled waveguides display complicated light propagation patterns, ranging from quasiperiodic to nearly chaotic. Taking a different approach, we spectrally engineer interwaveguide coupling to instigate self-imaging of the input light state at the array output and thus enable construction of novel high-fidelity interconnects. Simple implementation via modulation of the interwaveguide separations makes these interconnects realizable in all fabrication platforms. Their competitive advantages are negligible crosstalk-induced information loss, high density that exceeds the current standards by an order of magnitude, and compatibility with both classical and quantum information encoding schemes. Moreover, the wavelength-dependent self-imaging opens up new possibilities for wavelength and spatial division demultiplexing. The proposed analytical designs are supported by extensive numerical simulations of silicon-on-insulator, silicon nitride and silica glass waveguide arrays, and a statistical feasibility study. © 2023 Elsevier Ltd
T2  - Optics & Laser Technology
T1  - High-density optical interconnects based on self-imaging in coupled waveguide arrays
VL  - 163
SP  - 109381
DO  - 10.1016/j.optlastec.2023.109381
ER  - 
@article{
author = "Petrović, Jovana S. and Kršić, Jelena and Maluckov, Aleksandra and Veerman, J.J.P.",
year = "2023",
abstract = "Rapidly increasing demand for higher data bandwidths has motivated exploration of new communication channels based on spatially multiplexed in-fibre and on-chip coupled light guides. However, the conventionally used periodically arranged coupled waveguides display complicated light propagation patterns, ranging from quasiperiodic to nearly chaotic. Taking a different approach, we spectrally engineer interwaveguide coupling to instigate self-imaging of the input light state at the array output and thus enable construction of novel high-fidelity interconnects. Simple implementation via modulation of the interwaveguide separations makes these interconnects realizable in all fabrication platforms. Their competitive advantages are negligible crosstalk-induced information loss, high density that exceeds the current standards by an order of magnitude, and compatibility with both classical and quantum information encoding schemes. Moreover, the wavelength-dependent self-imaging opens up new possibilities for wavelength and spatial division demultiplexing. The proposed analytical designs are supported by extensive numerical simulations of silicon-on-insulator, silicon nitride and silica glass waveguide arrays, and a statistical feasibility study. © 2023 Elsevier Ltd",
journal = "Optics & Laser Technology",
title = "High-density optical interconnects based on self-imaging in coupled waveguide arrays",
volume = "163",
pages = "109381",
doi = "10.1016/j.optlastec.2023.109381"
}
Petrović, J. S., Kršić, J., Maluckov, A.,& Veerman, J.J.P.. (2023). High-density optical interconnects based on self-imaging in coupled waveguide arrays. in Optics & Laser Technology, 163, 109381.
https://doi.org/10.1016/j.optlastec.2023.109381
Petrović JS, Kršić J, Maluckov A, Veerman J. High-density optical interconnects based on self-imaging in coupled waveguide arrays. in Optics & Laser Technology. 2023;163:109381.
doi:10.1016/j.optlastec.2023.109381 .
Petrović, Jovana S., Kršić, Jelena, Maluckov, Aleksandra, Veerman, J.J.P., "High-density optical interconnects based on self-imaging in coupled waveguide arrays" in Optics & Laser Technology, 163 (2023):109381,
https://doi.org/10.1016/j.optlastec.2023.109381 . .

When Heart Beats Differently in Depression: Review of Nonlinear Heart Rate Variability Measures

Čukić, Milena; Savić, Danka A.; Sidorova, Julia

(2023)

TY  - JOUR
AU  - Čukić, Milena
AU  - Savić, Danka A.
AU  - Sidorova, Julia
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10758
AB  - Background: Disturbed heart dynamics in depression seriously increases mortality risk. Heart rate variability (HRV) is a rich source of information for studying this dynamics. This paper is a meta-analytic review with methodological commentary of the application of nonlinear analysis of HRV and its possibility to address cardiovascular diseases in depression. Objective: This paper aimed to appeal for the introduction of cardiological screening to patients with depression, because it is still far from established practice. The other (main) objective of the paper was to show that nonlinear methods in HRV analysis give better results than standard ones. Methods: We systematically searched on the web for papers on nonlinear analyses of HRV in depression, in line with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 framework recommendations. We scrutinized the chosen publications and performed random-effects meta-analysis, using the esci module in jamovi software where standardized effect sizes (ESs) are corrected to yield the proof of the practical utility of their results. Results: In all, 26 publications on the connection of nonlinear HRV measures and depression meeting our inclusion criteria were selected, examining a total of 1537 patients diagnosed with depression and 1041 healthy controls (N=2578). The overall ES (unbiased) was 1.03 (95% CI 0.703-1.35; diamond ratio 3.60). We performed 3 more meta-analytic comparisons, demonstrating the overall effectiveness of 3 groups of nonlinear analysis: detrended fluctuation analysis (overall ES 0.364, 95% CI 0.237-0.491), entropy-based measures (overall ES 1.05, 95% CI 0.572-1.52), and all other nonlinear measures (overall ES 0.702, 95% CI 0.422-0.982). The effectiveness of the applied methods of electrocardiogram analysis was compared and discussed in the light of detection and prevention of depression-related cardiovascular risk. Conclusions: We compared the ESs of nonlinear and conventional time and spectral methods (found in the literature) and demonstrated that those of the former are larger, which recommends their use for the early screening of cardiovascular abnormalities in patients with depression to prevent possible deleterious events. ©Milena Čukić, Danka Savić, Julia Sidorova.
T2  - JMIR Mental Health
T1  - When Heart Beats Differently in Depression: Review of Nonlinear Heart Rate Variability Measures
VL  - 10
SP  - e40342
DO  - 10.2196/40342
ER  - 
@article{
author = "Čukić, Milena and Savić, Danka A. and Sidorova, Julia",
year = "2023",
abstract = "Background: Disturbed heart dynamics in depression seriously increases mortality risk. Heart rate variability (HRV) is a rich source of information for studying this dynamics. This paper is a meta-analytic review with methodological commentary of the application of nonlinear analysis of HRV and its possibility to address cardiovascular diseases in depression. Objective: This paper aimed to appeal for the introduction of cardiological screening to patients with depression, because it is still far from established practice. The other (main) objective of the paper was to show that nonlinear methods in HRV analysis give better results than standard ones. Methods: We systematically searched on the web for papers on nonlinear analyses of HRV in depression, in line with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 framework recommendations. We scrutinized the chosen publications and performed random-effects meta-analysis, using the esci module in jamovi software where standardized effect sizes (ESs) are corrected to yield the proof of the practical utility of their results. Results: In all, 26 publications on the connection of nonlinear HRV measures and depression meeting our inclusion criteria were selected, examining a total of 1537 patients diagnosed with depression and 1041 healthy controls (N=2578). The overall ES (unbiased) was 1.03 (95% CI 0.703-1.35; diamond ratio 3.60). We performed 3 more meta-analytic comparisons, demonstrating the overall effectiveness of 3 groups of nonlinear analysis: detrended fluctuation analysis (overall ES 0.364, 95% CI 0.237-0.491), entropy-based measures (overall ES 1.05, 95% CI 0.572-1.52), and all other nonlinear measures (overall ES 0.702, 95% CI 0.422-0.982). The effectiveness of the applied methods of electrocardiogram analysis was compared and discussed in the light of detection and prevention of depression-related cardiovascular risk. Conclusions: We compared the ESs of nonlinear and conventional time and spectral methods (found in the literature) and demonstrated that those of the former are larger, which recommends their use for the early screening of cardiovascular abnormalities in patients with depression to prevent possible deleterious events. ©Milena Čukić, Danka Savić, Julia Sidorova.",
journal = "JMIR Mental Health",
title = "When Heart Beats Differently in Depression: Review of Nonlinear Heart Rate Variability Measures",
volume = "10",
pages = "e40342",
doi = "10.2196/40342"
}
Čukić, M., Savić, D. A.,& Sidorova, J.. (2023). When Heart Beats Differently in Depression: Review of Nonlinear Heart Rate Variability Measures. in JMIR Mental Health, 10, e40342.
https://doi.org/10.2196/40342
Čukić M, Savić DA, Sidorova J. When Heart Beats Differently in Depression: Review of Nonlinear Heart Rate Variability Measures. in JMIR Mental Health. 2023;10:e40342.
doi:10.2196/40342 .
Čukić, Milena, Savić, Danka A., Sidorova, Julia, "When Heart Beats Differently in Depression: Review of Nonlinear Heart Rate Variability Measures" in JMIR Mental Health, 10 (2023):e40342,
https://doi.org/10.2196/40342 . .
1

The Na+/K+-ATPase: A potential therapeutic target in cardiometabolic diseases

Obradović, Milan M.; Sudar-Milovanović, Emina; Gluvić, Zoran; Banjac, Katarina; Rizzo, Manfredi; Isenović, Esma R.

(2023)

TY  - JOUR
AU  - Obradović, Milan M.
AU  - Sudar-Milovanović, Emina
AU  - Gluvić, Zoran
AU  - Banjac, Katarina
AU  - Rizzo, Manfredi
AU  - Isenović, Esma R.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10756
AB  - Cardiometabolic diseases (CMD) are a direct consequence of modern living and contribute to the development of multisystem diseases such as cardiovascular diseases and diabetes mellitus (DM). CMD has reached epidemic proportions worldwide. A sodium pump (Na + /K + -ATPase) is found in most eukaryotic cells’ membrane and controls many essential cellular functions directly or indirectly. This ion transporter and its isoforms are important in the pathogenesis of some pathological processes, including CMD. The structure and function of Na + /K + -ATPase, its expression and distribution in tissues, and its interactions with known ligands such as cardiotonic steroids and other suspected endogenous regulators are discussed in this review. In addition, we reviewed recent literature data related to the involvement of Na + /K + -ATPase activity dysfunction in CMD, focusing on the Na + /K + -ATPase as a potential therapeutic target in CMD.
T2  - Frontiers in Endocrinology
T1  - The Na+/K+-ATPase: A potential therapeutic target in cardiometabolic diseases
VL  - 14
DO  - 10.3389/fendo.2023.1150171
ER  - 
@article{
author = "Obradović, Milan M. and Sudar-Milovanović, Emina and Gluvić, Zoran and Banjac, Katarina and Rizzo, Manfredi and Isenović, Esma R.",
year = "2023",
abstract = "Cardiometabolic diseases (CMD) are a direct consequence of modern living and contribute to the development of multisystem diseases such as cardiovascular diseases and diabetes mellitus (DM). CMD has reached epidemic proportions worldwide. A sodium pump (Na + /K + -ATPase) is found in most eukaryotic cells’ membrane and controls many essential cellular functions directly or indirectly. This ion transporter and its isoforms are important in the pathogenesis of some pathological processes, including CMD. The structure and function of Na + /K + -ATPase, its expression and distribution in tissues, and its interactions with known ligands such as cardiotonic steroids and other suspected endogenous regulators are discussed in this review. In addition, we reviewed recent literature data related to the involvement of Na + /K + -ATPase activity dysfunction in CMD, focusing on the Na + /K + -ATPase as a potential therapeutic target in CMD.",
journal = "Frontiers in Endocrinology",
title = "The Na+/K+-ATPase: A potential therapeutic target in cardiometabolic diseases",
volume = "14",
doi = "10.3389/fendo.2023.1150171"
}
Obradović, M. M., Sudar-Milovanović, E., Gluvić, Z., Banjac, K., Rizzo, M.,& Isenović, E. R.. (2023). The Na+/K+-ATPase: A potential therapeutic target in cardiometabolic diseases. in Frontiers in Endocrinology, 14.
https://doi.org/10.3389/fendo.2023.1150171
Obradović MM, Sudar-Milovanović E, Gluvić Z, Banjac K, Rizzo M, Isenović ER. The Na+/K+-ATPase: A potential therapeutic target in cardiometabolic diseases. in Frontiers in Endocrinology. 2023;14.
doi:10.3389/fendo.2023.1150171 .
Obradović, Milan M., Sudar-Milovanović, Emina, Gluvić, Zoran, Banjac, Katarina, Rizzo, Manfredi, Isenović, Esma R., "The Na+/K+-ATPase: A potential therapeutic target in cardiometabolic diseases" in Frontiers in Endocrinology, 14 (2023),
https://doi.org/10.3389/fendo.2023.1150171 . .

Application of composite construction and demolition debris in heavy metals removal from industrial wastewater

Jelić, Ivana V.; Antonijević, Dragi; Šljivić-Ivanović, Marija Z.; Dimović, Slavko

(2023)

TY  - JOUR
AU  - Jelić, Ivana V.
AU  - Antonijević, Dragi
AU  - Šljivić-Ivanović, Marija Z.
AU  - Dimović, Slavko
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10755
AB  - The utilization of construction and demolition debris in industrial wastewater treatment by sorption of Co2+ and Ni2+ ions was investigated. Selected waste composites are cost-effective and locally available, still their sorption character-istics and application are not sufficiently investigated. The samples of concrete, facade, ceramic materials, and asphalt were characterized in terms of mineral and surface composition, radioactivity, and stability at different pH values, as well as pH values of suspension and filtrate and electrical conductivity of the fil-trate. The sorption capacities were determined in batch experimental conditions in one and multi-component solutions. Characterization showed different crystal structures and mineralogical compositions of components. The results of gamma spectrometry confirmed the radiological safety of samples. Based on stability testing results, waste materials are suitable for further utilization and do not pose any risk to the environment. The overall sorption results suggested that cement-based materials, in addition to high affinity for the tested ions, represent a sorbent that binds contaminants firmly enough, reduces their mobility and bioa-vailability, and are suitable for removing Co2+ and Ni2+ ions from wastewaters.
T2  - Thermal Science
T1  - Application of composite construction and demolition debris in heavy metals removal from industrial wastewater
VL  - 27
IS  - 1 Part A
SP  - 1
EP  - 10
DO  - 10.2298/TSCI2301001J
ER  - 
@article{
author = "Jelić, Ivana V. and Antonijević, Dragi and Šljivić-Ivanović, Marija Z. and Dimović, Slavko",
year = "2023",
abstract = "The utilization of construction and demolition debris in industrial wastewater treatment by sorption of Co2+ and Ni2+ ions was investigated. Selected waste composites are cost-effective and locally available, still their sorption character-istics and application are not sufficiently investigated. The samples of concrete, facade, ceramic materials, and asphalt were characterized in terms of mineral and surface composition, radioactivity, and stability at different pH values, as well as pH values of suspension and filtrate and electrical conductivity of the fil-trate. The sorption capacities were determined in batch experimental conditions in one and multi-component solutions. Characterization showed different crystal structures and mineralogical compositions of components. The results of gamma spectrometry confirmed the radiological safety of samples. Based on stability testing results, waste materials are suitable for further utilization and do not pose any risk to the environment. The overall sorption results suggested that cement-based materials, in addition to high affinity for the tested ions, represent a sorbent that binds contaminants firmly enough, reduces their mobility and bioa-vailability, and are suitable for removing Co2+ and Ni2+ ions from wastewaters.",
journal = "Thermal Science",
title = "Application of composite construction and demolition debris in heavy metals removal from industrial wastewater",
volume = "27",
number = "1 Part A",
pages = "1-10",
doi = "10.2298/TSCI2301001J"
}
Jelić, I. V., Antonijević, D., Šljivić-Ivanović, M. Z.,& Dimović, S.. (2023). Application of composite construction and demolition debris in heavy metals removal from industrial wastewater. in Thermal Science, 27(1 Part A), 1-10.
https://doi.org/10.2298/TSCI2301001J
Jelić IV, Antonijević D, Šljivić-Ivanović MZ, Dimović S. Application of composite construction and demolition debris in heavy metals removal from industrial wastewater. in Thermal Science. 2023;27(1 Part A):1-10.
doi:10.2298/TSCI2301001J .
Jelić, Ivana V., Antonijević, Dragi, Šljivić-Ivanović, Marija Z., Dimović, Slavko, "Application of composite construction and demolition debris in heavy metals removal from industrial wastewater" in Thermal Science, 27, no. 1 Part A (2023):1-10,
https://doi.org/10.2298/TSCI2301001J . .

The Role of miRNAs in Metabolic Diseases

Mačvanin, Mirjana; Obradović, Milan M.; Zafirović, Sonja; Stanimirović, Julijana; Isenović, Esma R.

(2023)

TY  - JOUR
AU  - Mačvanin, Mirjana
AU  - Obradović, Milan M.
AU  - Zafirović, Sonja
AU  - Stanimirović, Julijana
AU  - Isenović, Esma R.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10757
AB  - Metabolic diseases such as obesity, diabetes, dyslipidemia, and insulin resistance are characterized by glucose and lipid metabolism alterations and represent a global health problem. Many studies have established the crucial role of micro-ribonucleic acids (miRNAs) in controlling metabolic processes in various tissues. miRNAs are single-stranded, highly conserved non-coding RNAs containing 20-24 oligonucleotides that are expressed in a tissue-specific manner. miRNAs mainly interact through base pairing with 3' untranslated regions of target gene mRNAs to promote inhibition of their translation. miRNAs regulate the expression of as many as 30% of the human genes and have a role in crucial physiological processes such as human growth and development, cell proliferation, apoptosis, and metabolism. The number of miRNA molecules with a confirmed role in the pathogenesis of metabolic diseases is quickly expanding due to the availability of high-throughput methodologies for their identification. In this review, we present recent findings regarding the role of miRNAs as endocrine signaling molecules involved in the regulation of insulin production and fat metabolism. We discuss the potential of extracellular miRNAs present in biological fluids miRNAs as biomarkers for the prediction of diabetes and MetS. We also give an updated overview of therapeutic interventions based on antisense oligonucleotides and the CRISPR/Cas9 editing platform for manipulating levels of miRNAs involved in metabolic disorders. © 2023 Bentham Science Publishers.
T2  - Current Medicinal Chemistry
T1  - The Role of miRNAs in Metabolic Diseases
VL  - 30
IS  - 17
SP  - 1922
EP  - 1944
DO  - 10.2174/0929867329666220801161536
ER  - 
@article{
author = "Mačvanin, Mirjana and Obradović, Milan M. and Zafirović, Sonja and Stanimirović, Julijana and Isenović, Esma R.",
year = "2023",
abstract = "Metabolic diseases such as obesity, diabetes, dyslipidemia, and insulin resistance are characterized by glucose and lipid metabolism alterations and represent a global health problem. Many studies have established the crucial role of micro-ribonucleic acids (miRNAs) in controlling metabolic processes in various tissues. miRNAs are single-stranded, highly conserved non-coding RNAs containing 20-24 oligonucleotides that are expressed in a tissue-specific manner. miRNAs mainly interact through base pairing with 3' untranslated regions of target gene mRNAs to promote inhibition of their translation. miRNAs regulate the expression of as many as 30% of the human genes and have a role in crucial physiological processes such as human growth and development, cell proliferation, apoptosis, and metabolism. The number of miRNA molecules with a confirmed role in the pathogenesis of metabolic diseases is quickly expanding due to the availability of high-throughput methodologies for their identification. In this review, we present recent findings regarding the role of miRNAs as endocrine signaling molecules involved in the regulation of insulin production and fat metabolism. We discuss the potential of extracellular miRNAs present in biological fluids miRNAs as biomarkers for the prediction of diabetes and MetS. We also give an updated overview of therapeutic interventions based on antisense oligonucleotides and the CRISPR/Cas9 editing platform for manipulating levels of miRNAs involved in metabolic disorders. © 2023 Bentham Science Publishers.",
journal = "Current Medicinal Chemistry",
title = "The Role of miRNAs in Metabolic Diseases",
volume = "30",
number = "17",
pages = "1922-1944",
doi = "10.2174/0929867329666220801161536"
}
Mačvanin, M., Obradović, M. M., Zafirović, S., Stanimirović, J.,& Isenović, E. R.. (2023). The Role of miRNAs in Metabolic Diseases. in Current Medicinal Chemistry, 30(17), 1922-1944.
https://doi.org/10.2174/0929867329666220801161536
Mačvanin M, Obradović MM, Zafirović S, Stanimirović J, Isenović ER. The Role of miRNAs in Metabolic Diseases. in Current Medicinal Chemistry. 2023;30(17):1922-1944.
doi:10.2174/0929867329666220801161536 .
Mačvanin, Mirjana, Obradović, Milan M., Zafirović, Sonja, Stanimirović, Julijana, Isenović, Esma R., "The Role of miRNAs in Metabolic Diseases" in Current Medicinal Chemistry, 30, no. 17 (2023):1922-1944,
https://doi.org/10.2174/0929867329666220801161536 . .
4
3

Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats

Kostić, Milan; Korićanac, Goran; Tepavčević, Snežana; Stanišić, Jelena; Romić, Snježana Đ.; Ćulafić, Tijana; Ivković, Tamara; Stojiljković, Mojca D.

(2023)

TY  - JOUR
AU  - Kostić, Milan
AU  - Korićanac, Goran
AU  - Tepavčević, Snežana
AU  - Stanišić, Jelena
AU  - Romić, Snježana Đ.
AU  - Ćulafić, Tijana
AU  - Ivković, Tamara
AU  - Stojiljković, Mojca D.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10747
AB  - Background and Aim: Excessive fructose consumption along with a sedentary lifestyle provokes metabolic disorders and cardiovascular diseases. Fructose overload causes cardiac insulin resistance and increases reliance on fatty acid (FA) uptake and catabolism. The cardiometabolic benefits of exercise training have long been appreciated. The goal of the presented study is to shed a new light to the preventive role of exercise training on cardiac lipid metabolism in fructose-fed rats. Methods: Male Wistar rats were divided into control (C), sedentary fructose (F), and exercised fructose (EF) groups. Fructose was given as a 10% fructose solution in drinking water for 9 weeks. Low-intensity exercise training was applied for 9 weeks. The protein expression and subcellular localization of Lipin1, peroxisome proliferator-activated receptor α (PPARα), and peroxisome proliferator-activated receptor-γcoactivator 1 α (PGC1) were analyzed in the heart using Western blot. Cardiac forkhead box transcription factor 1 (FOXO1) and sirtuin 1 (SIRT1) protein levels were also evaluated. Gene expression of long-chain acyl-CoA dehydrogenase was analyzed by quantitative polymerase chain reaction. Results: Exercise training has augmented the expression of main regulators of FA oxidation in the heart and achieves its effect by increasing the nuclear content of PPARα, Lipin1, and FOXO1 compared with the fructose group (P = 0.0422, P = 0.000045, P = 0.00958, respectively). In addition, Lipin1, FOXO1, and SIRT1 were increased in nuclear extract after exercise compared with the control group (P = 0.000043, P = 0.0417, P = 0.0329, respectively). In cardiac lysate, low-intensity exercise caused significantly increased protein level of PPARα, PGC1, FOXO1, and SIRT1 compared with control (P = 0.0377, P = 0.0275, P = 0.0096, P = 0.0282, respectively) and PGC1 level compared with the fructose group (P = 0.0417). Conclusion: The obtained results imply that the heart with a metabolic burden additionally relies on FA as an energy substrate after low-intensity running. © Copyright 2023, Mary Ann Liebert, Inc., publishers 2023.
T2  - Metabolic Syndrome and Related Disorders
T1  - Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats
VL  - 21
IS  - 2
SP  - 122
EP  - 131
DO  - 10.1089/met.2022.0078
ER  - 
@article{
author = "Kostić, Milan and Korićanac, Goran and Tepavčević, Snežana and Stanišić, Jelena and Romić, Snježana Đ. and Ćulafić, Tijana and Ivković, Tamara and Stojiljković, Mojca D.",
year = "2023",
abstract = "Background and Aim: Excessive fructose consumption along with a sedentary lifestyle provokes metabolic disorders and cardiovascular diseases. Fructose overload causes cardiac insulin resistance and increases reliance on fatty acid (FA) uptake and catabolism. The cardiometabolic benefits of exercise training have long been appreciated. The goal of the presented study is to shed a new light to the preventive role of exercise training on cardiac lipid metabolism in fructose-fed rats. Methods: Male Wistar rats were divided into control (C), sedentary fructose (F), and exercised fructose (EF) groups. Fructose was given as a 10% fructose solution in drinking water for 9 weeks. Low-intensity exercise training was applied for 9 weeks. The protein expression and subcellular localization of Lipin1, peroxisome proliferator-activated receptor α (PPARα), and peroxisome proliferator-activated receptor-γcoactivator 1 α (PGC1) were analyzed in the heart using Western blot. Cardiac forkhead box transcription factor 1 (FOXO1) and sirtuin 1 (SIRT1) protein levels were also evaluated. Gene expression of long-chain acyl-CoA dehydrogenase was analyzed by quantitative polymerase chain reaction. Results: Exercise training has augmented the expression of main regulators of FA oxidation in the heart and achieves its effect by increasing the nuclear content of PPARα, Lipin1, and FOXO1 compared with the fructose group (P = 0.0422, P = 0.000045, P = 0.00958, respectively). In addition, Lipin1, FOXO1, and SIRT1 were increased in nuclear extract after exercise compared with the control group (P = 0.000043, P = 0.0417, P = 0.0329, respectively). In cardiac lysate, low-intensity exercise caused significantly increased protein level of PPARα, PGC1, FOXO1, and SIRT1 compared with control (P = 0.0377, P = 0.0275, P = 0.0096, P = 0.0282, respectively) and PGC1 level compared with the fructose group (P = 0.0417). Conclusion: The obtained results imply that the heart with a metabolic burden additionally relies on FA as an energy substrate after low-intensity running. © Copyright 2023, Mary Ann Liebert, Inc., publishers 2023.",
journal = "Metabolic Syndrome and Related Disorders",
title = "Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats",
volume = "21",
number = "2",
pages = "122-131",
doi = "10.1089/met.2022.0078"
}
Kostić, M., Korićanac, G., Tepavčević, S., Stanišić, J., Romić, S. Đ., Ćulafić, T., Ivković, T.,& Stojiljković, M. D.. (2023). Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats. in Metabolic Syndrome and Related Disorders, 21(2), 122-131.
https://doi.org/10.1089/met.2022.0078
Kostić M, Korićanac G, Tepavčević S, Stanišić J, Romić SĐ, Ćulafić T, Ivković T, Stojiljković MD. Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats. in Metabolic Syndrome and Related Disorders. 2023;21(2):122-131.
doi:10.1089/met.2022.0078 .
Kostić, Milan, Korićanac, Goran, Tepavčević, Snežana, Stanišić, Jelena, Romić, Snježana Đ., Ćulafić, Tijana, Ivković, Tamara, Stojiljković, Mojca D., "Low-Intensity Exercise Affects Cardiac Fatty Acid Oxidation by Increasing the Nuclear Content of PPARα, FOXO1, and Lipin1 in Fructose-Fed Rats" in Metabolic Syndrome and Related Disorders, 21, no. 2 (2023):122-131,
https://doi.org/10.1089/met.2022.0078 . .

Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination

Đukić, Ivana; Kaličanin, Nevena; Senćanski, Milan V.; Pajović, Snežana B.; Milićević, Jelena S.; Prljić, Jelena; Paessler, Slobodan; Prodanović, Radivoje; Glišić, Sanja

(2023)

TY  - JOUR
AU  - Đukić, Ivana
AU  - Kaličanin, Nevena
AU  - Senćanski, Milan V.
AU  - Pajović, Snežana B.
AU  - Milićević, Jelena S.
AU  - Prljić, Jelena
AU  - Paessler, Slobodan
AU  - Prodanović, Radivoje
AU  - Glišić, Sanja
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10629
AB  - Drug resistance is a critical problem in health care that affects therapy outcomes and requires new approaches to drugdesign. SARS-CoV-2 Mpro mutations are of concern as they can potentially reduce therapeutic efficacy. Viral infections are amongst themany disorders for which nutraceuticals have been employed as an adjunct therapy. The aim of this study was to examine the potentialin vitro activity of L-arginine and vitamin C against SARS-CoV-2 Mpro. Methods: The Mpro inhibition assay was developed by cloning,expression, purification, and characterization of Mpro. Selected compounds were then screened for protease inhibition. Results: Largininewas found to be active against SARS-CoV-2 Mpro, while a vitamin C/L-arginine combination had a synergistic antiviral actionagainst Mpro. These findings confirm the results of our previous in silico repurposing study that showed L-arginine and vitamin C werepotential Mpro inhibitors. Moreover, they suggest a possible molecular mechanism to explain the beneficial effect of arginine in COVIDpatients. Conclusions: The findings of the current study are important because they help to identify COVID-19 treatments that areefficient, inexpensive, and have a favorable safety profile. The results of this study also suggest a possible adjuvant nutritional strategyfor COVID-19 that could be used in conjunction with pharmacological agents.
T2  - Frontiers in Bioscience - Landmark
T1  - Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination
VL  - 28
IS  - 1
SP  - 8
DO  - 10.31083/j.fbl2801008
ER  - 
@article{
author = "Đukić, Ivana and Kaličanin, Nevena and Senćanski, Milan V. and Pajović, Snežana B. and Milićević, Jelena S. and Prljić, Jelena and Paessler, Slobodan and Prodanović, Radivoje and Glišić, Sanja",
year = "2023",
abstract = "Drug resistance is a critical problem in health care that affects therapy outcomes and requires new approaches to drugdesign. SARS-CoV-2 Mpro mutations are of concern as they can potentially reduce therapeutic efficacy. Viral infections are amongst themany disorders for which nutraceuticals have been employed as an adjunct therapy. The aim of this study was to examine the potentialin vitro activity of L-arginine and vitamin C against SARS-CoV-2 Mpro. Methods: The Mpro inhibition assay was developed by cloning,expression, purification, and characterization of Mpro. Selected compounds were then screened for protease inhibition. Results: Largininewas found to be active against SARS-CoV-2 Mpro, while a vitamin C/L-arginine combination had a synergistic antiviral actionagainst Mpro. These findings confirm the results of our previous in silico repurposing study that showed L-arginine and vitamin C werepotential Mpro inhibitors. Moreover, they suggest a possible molecular mechanism to explain the beneficial effect of arginine in COVIDpatients. Conclusions: The findings of the current study are important because they help to identify COVID-19 treatments that areefficient, inexpensive, and have a favorable safety profile. The results of this study also suggest a possible adjuvant nutritional strategyfor COVID-19 that could be used in conjunction with pharmacological agents.",
journal = "Frontiers in Bioscience - Landmark",
title = "Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination",
volume = "28",
number = "1",
pages = "8",
doi = "10.31083/j.fbl2801008"
}
Đukić, I., Kaličanin, N., Senćanski, M. V., Pajović, S. B., Milićević, J. S., Prljić, J., Paessler, S., Prodanović, R.,& Glišić, S.. (2023). Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination. in Frontiers in Bioscience - Landmark, 28(1), 8.
https://doi.org/10.31083/j.fbl2801008
Đukić I, Kaličanin N, Senćanski MV, Pajović SB, Milićević JS, Prljić J, Paessler S, Prodanović R, Glišić S. Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination. in Frontiers in Bioscience - Landmark. 2023;28(1):8.
doi:10.31083/j.fbl2801008 .
Đukić, Ivana, Kaličanin, Nevena, Senćanski, Milan V., Pajović, Snežana B., Milićević, Jelena S., Prljić, Jelena, Paessler, Slobodan, Prodanović, Radivoje, Glišić, Sanja, "Inhibition of SARS-CoV-2 Mpro with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination" in Frontiers in Bioscience - Landmark, 28, no. 1 (2023):8,
https://doi.org/10.31083/j.fbl2801008 . .
1

Molecularly Imprinted Plasmonic-Based Sensors for Environmental Contaminants—Current State and Future Perspectives

Lazarević-Pašti, Tamara; Tasić, Tamara; Milanković, Vedran; Potkonjak, Nebojša I.

(2023)

TY  - JOUR
AU  - Lazarević-Pašti, Tamara
AU  - Tasić, Tamara
AU  - Milanković, Vedran
AU  - Potkonjak, Nebojša I.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10616
AB  - The increase of production and consumption persistently introduce different pollutants into the environment. The constant development and improvement of analytical methods for tracking environmental contaminants are essential. The demand for high sample throughput analysis has hit the spotlight for developing selective sensors to avoid time-consuming sample preparation techniques. In addition, the sensor’s sensitivity should satisfy the rigorous demands of harmful compound tracking. Molecularly imprinted plasmonic-based sensors are excellent candidates to overcome selectivity and sensitivity issues. Molecularly imprinted polymers are robust, stable in aqueous and organic solvents, stable at extreme pHs and temperatures, and include a low-cost synthesis procedure. Combined with plasmonic-based techniques, they are the perspective choice for applications in the field of environmental protection. Plasmonic-based sensors offer a lower limit of detection, a broad linearity range, high sensitivity, and high selectivity compared to other detection techniques. This review outlines the optical plasmonic detection of different environmental contaminants with molecularly imprinted polymers as sensing elements. The main focus is on the environmental pollutants affecting human and animal health, such as pesticides, pharmaceuticals, hormones, microorganisms, polycyclic aromatic hydrocarbons, dyes, and metal particles. Although molecularly imprinted plasmonic-based sensors currently have their application mostly in the biomedical field, we are eager to point them out as a highly prospective solution for many environmental problems.
T2  - Chemosensors
T1  - Molecularly Imprinted Plasmonic-Based Sensors for Environmental Contaminants—Current State and Future Perspectives
VL  - 11
IS  - 1
SP  - 35
DO  - 10.3390/chemosensors11010035
ER  - 
@article{
author = "Lazarević-Pašti, Tamara and Tasić, Tamara and Milanković, Vedran and Potkonjak, Nebojša I.",
year = "2023",
abstract = "The increase of production and consumption persistently introduce different pollutants into the environment. The constant development and improvement of analytical methods for tracking environmental contaminants are essential. The demand for high sample throughput analysis has hit the spotlight for developing selective sensors to avoid time-consuming sample preparation techniques. In addition, the sensor’s sensitivity should satisfy the rigorous demands of harmful compound tracking. Molecularly imprinted plasmonic-based sensors are excellent candidates to overcome selectivity and sensitivity issues. Molecularly imprinted polymers are robust, stable in aqueous and organic solvents, stable at extreme pHs and temperatures, and include a low-cost synthesis procedure. Combined with plasmonic-based techniques, they are the perspective choice for applications in the field of environmental protection. Plasmonic-based sensors offer a lower limit of detection, a broad linearity range, high sensitivity, and high selectivity compared to other detection techniques. This review outlines the optical plasmonic detection of different environmental contaminants with molecularly imprinted polymers as sensing elements. The main focus is on the environmental pollutants affecting human and animal health, such as pesticides, pharmaceuticals, hormones, microorganisms, polycyclic aromatic hydrocarbons, dyes, and metal particles. Although molecularly imprinted plasmonic-based sensors currently have their application mostly in the biomedical field, we are eager to point them out as a highly prospective solution for many environmental problems.",
journal = "Chemosensors",
title = "Molecularly Imprinted Plasmonic-Based Sensors for Environmental Contaminants—Current State and Future Perspectives",
volume = "11",
number = "1",
pages = "35",
doi = "10.3390/chemosensors11010035"
}
Lazarević-Pašti, T., Tasić, T., Milanković, V.,& Potkonjak, N. I.. (2023). Molecularly Imprinted Plasmonic-Based Sensors for Environmental Contaminants—Current State and Future Perspectives. in Chemosensors, 11(1), 35.
https://doi.org/10.3390/chemosensors11010035
Lazarević-Pašti T, Tasić T, Milanković V, Potkonjak NI. Molecularly Imprinted Plasmonic-Based Sensors for Environmental Contaminants—Current State and Future Perspectives. in Chemosensors. 2023;11(1):35.
doi:10.3390/chemosensors11010035 .
Lazarević-Pašti, Tamara, Tasić, Tamara, Milanković, Vedran, Potkonjak, Nebojša I., "Molecularly Imprinted Plasmonic-Based Sensors for Environmental Contaminants—Current State and Future Perspectives" in Chemosensors, 11, no. 1 (2023):35,
https://doi.org/10.3390/chemosensors11010035 . .
1

Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers

Ahmetović, Sanita; Vasiljević, Zorka Ž.; Rajić, Vladimir; Bartolić, Dragana; Novaković, Mirjana M.; Tadić, Nenad B.; Cvjetićanin, Nikola; Nikolić, Maria Vesna

(2023)

TY  - JOUR
AU  - Ahmetović, Sanita
AU  - Vasiljević, Zorka Ž.
AU  - Rajić, Vladimir
AU  - Bartolić, Dragana
AU  - Novaković, Mirjana M.
AU  - Tadić, Nenad B.
AU  - Cvjetićanin, Nikola
AU  - Nikolić, Maria Vesna
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10448
AB  - Pure and samarium (Sm3+) - or zirconium (Zr4+)-doped TiO2 nanofibers were synthesized by electrospinning method followed by calcination at 500 °C for 1 h. As-spun fibers were smooth, straight and continuous, whilst EDS analysis confirmed the fiber composition and incorporation of dopants in the fibers. Doping with Sm3+ and Zr4+ greatly inhibited the phase transformation of anatase to rutile, by surrounding of Sm3+ ions through formation of Ti-O-Sm bonds and by replacement of Ti4+ ions with larger Zr4+ ions. This was confirmed by HRTEM and SAED analysis. The size of nanofibers was determined to be 133 nm, 175 nm and 155 nm for pure, (0.5%)Sm3+:TiO2 and (1%)Zr4+:TiO2, respectively. After calcination, TiO2 crystal lattice with interplanar spacing of 0.353 nm of (101) crystal plane was not significantly disturbed by Sm doping whilst crystal lattice spacing of 0.357 nm of (101) planes of anatase phase in case TiO2:1.0%Zr4+, significantly differs from the value of pure TiO2 (0.352 nm), thus implying that Zr was doped into substitutional sites of the TiO2 lattice. The indirect band gaps were calculated to be in the range 3.07–3.24 eV. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ exhibited higher specific surface area, of 47.1 and 59.4 m2/g, respectively, than pure TiO2 fibers (19.7 m2/g). Effects of Sm3+ and Zr4+ dopant content on the photodegradation efficiency of methylene blue (MB) were studied. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ nanofibers have shown the highest photocatalytic activity of 97% and 98% with constant rates 0.01768 min−1 and 0.01939 min−1, respectively, within180 min irradiation under visible light.
T2  - Journal of Alloys and Compounds
T1  - Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers
VL  - 930
SP  - 167423
DO  - 10.1016/j.jallcom.2022.167423
ER  - 
@article{
author = "Ahmetović, Sanita and Vasiljević, Zorka Ž. and Rajić, Vladimir and Bartolić, Dragana and Novaković, Mirjana M. and Tadić, Nenad B. and Cvjetićanin, Nikola and Nikolić, Maria Vesna",
year = "2023",
abstract = "Pure and samarium (Sm3+) - or zirconium (Zr4+)-doped TiO2 nanofibers were synthesized by electrospinning method followed by calcination at 500 °C for 1 h. As-spun fibers were smooth, straight and continuous, whilst EDS analysis confirmed the fiber composition and incorporation of dopants in the fibers. Doping with Sm3+ and Zr4+ greatly inhibited the phase transformation of anatase to rutile, by surrounding of Sm3+ ions through formation of Ti-O-Sm bonds and by replacement of Ti4+ ions with larger Zr4+ ions. This was confirmed by HRTEM and SAED analysis. The size of nanofibers was determined to be 133 nm, 175 nm and 155 nm for pure, (0.5%)Sm3+:TiO2 and (1%)Zr4+:TiO2, respectively. After calcination, TiO2 crystal lattice with interplanar spacing of 0.353 nm of (101) crystal plane was not significantly disturbed by Sm doping whilst crystal lattice spacing of 0.357 nm of (101) planes of anatase phase in case TiO2:1.0%Zr4+, significantly differs from the value of pure TiO2 (0.352 nm), thus implying that Zr was doped into substitutional sites of the TiO2 lattice. The indirect band gaps were calculated to be in the range 3.07–3.24 eV. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ exhibited higher specific surface area, of 47.1 and 59.4 m2/g, respectively, than pure TiO2 fibers (19.7 m2/g). Effects of Sm3+ and Zr4+ dopant content on the photodegradation efficiency of methylene blue (MB) were studied. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ nanofibers have shown the highest photocatalytic activity of 97% and 98% with constant rates 0.01768 min−1 and 0.01939 min−1, respectively, within180 min irradiation under visible light.",
journal = "Journal of Alloys and Compounds",
title = "Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers",
volume = "930",
pages = "167423",
doi = "10.1016/j.jallcom.2022.167423"
}
Ahmetović, S., Vasiljević, Z. Ž., Rajić, V., Bartolić, D., Novaković, M. M., Tadić, N. B., Cvjetićanin, N.,& Nikolić, M. V.. (2023). Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers. in Journal of Alloys and Compounds, 930, 167423.
https://doi.org/10.1016/j.jallcom.2022.167423
Ahmetović S, Vasiljević ZŽ, Rajić V, Bartolić D, Novaković MM, Tadić NB, Cvjetićanin N, Nikolić MV. Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers. in Journal of Alloys and Compounds. 2023;930:167423.
doi:10.1016/j.jallcom.2022.167423 .
Ahmetović, Sanita, Vasiljević, Zorka Ž., Rajić, Vladimir, Bartolić, Dragana, Novaković, Mirjana M., Tadić, Nenad B., Cvjetićanin, Nikola, Nikolić, Maria Vesna, "Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers" in Journal of Alloys and Compounds, 930 (2023):167423,
https://doi.org/10.1016/j.jallcom.2022.167423 . .
2
1

Preparation and Characterization of Geopolymers Based on Metakaolin with the Addition of Organic Phase PVA

Ivanović, Marija M.; Knežević, Sanja; Radović, Ivona; Kljajević, Ljiljana M.; Mirković, Miljana M.; Nenadović, Miloš; Nenadović, Snežana S.

(2023)

TY  - JOUR
AU  - Ivanović, Marija M.
AU  - Knežević, Sanja
AU  - Radović, Ivona
AU  - Kljajević, Ljiljana M.
AU  - Mirković, Miljana M.
AU  - Nenadović, Miloš
AU  - Nenadović, Snežana S.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10742
AB  - Geopolymers have excellent physical and mechanical properties, so they can be used as a substitute for ordinary polymers. Geopolymers are ceramic materials, which exhibit the property of brittleness, which can be a limitation in some structural applications. To overcome this shortcoming, a new group of materials (organic geopolymers) was developed. The aim of this work is the synthesis of organic (hybrid) geopolymers. A geopolymer based on metakaolin was synthesized as a reference sample, while polyvinyl alcohol was added as an organic phase for synthesizing a hybrid geopolymer. It was concluded that the systems follow the rule of behavior in liquid systems. The chemical composition of the samples was determined by X-ray fluorescence analysis (XRF). Structural and phase characterization of hybrid and reference materials were analyzed using X-ray diffraction (XRD)and Fourier-transform infrared spectroscopy (FTIR), which revealed new phases in the PVA-added samples. The results show that the content of added PVA in the reaction mixture affects the phase composition of the synthesized materials. To examine the possibility of adsorption of the samples, Ultraviolet-visible spectroscopy (UV/VIS) was used. The morphology was analyzed using a scanning electron microscope with energy dispersive spectroscopy (SEM/EDS), where efflorescence was observed and identified. After characterizing the geopolymer with the addition of PVA, we obtained a material that was far more porous than the basic sample, and we can conclude that we have synthesized a material that shows good mechanical properties.
T2  - Sustainability
T1  - Preparation and Characterization of Geopolymers Based on Metakaolin with the Addition of Organic Phase PVA
VL  - 15
IS  - 5
SP  - 4441
DO  - 10.3390/su15054441
ER  - 
@article{
author = "Ivanović, Marija M. and Knežević, Sanja and Radović, Ivona and Kljajević, Ljiljana M. and Mirković, Miljana M. and Nenadović, Miloš and Nenadović, Snežana S.",
year = "2023",
abstract = "Geopolymers have excellent physical and mechanical properties, so they can be used as a substitute for ordinary polymers. Geopolymers are ceramic materials, which exhibit the property of brittleness, which can be a limitation in some structural applications. To overcome this shortcoming, a new group of materials (organic geopolymers) was developed. The aim of this work is the synthesis of organic (hybrid) geopolymers. A geopolymer based on metakaolin was synthesized as a reference sample, while polyvinyl alcohol was added as an organic phase for synthesizing a hybrid geopolymer. It was concluded that the systems follow the rule of behavior in liquid systems. The chemical composition of the samples was determined by X-ray fluorescence analysis (XRF). Structural and phase characterization of hybrid and reference materials were analyzed using X-ray diffraction (XRD)and Fourier-transform infrared spectroscopy (FTIR), which revealed new phases in the PVA-added samples. The results show that the content of added PVA in the reaction mixture affects the phase composition of the synthesized materials. To examine the possibility of adsorption of the samples, Ultraviolet-visible spectroscopy (UV/VIS) was used. The morphology was analyzed using a scanning electron microscope with energy dispersive spectroscopy (SEM/EDS), where efflorescence was observed and identified. After characterizing the geopolymer with the addition of PVA, we obtained a material that was far more porous than the basic sample, and we can conclude that we have synthesized a material that shows good mechanical properties.",
journal = "Sustainability",
title = "Preparation and Characterization of Geopolymers Based on Metakaolin with the Addition of Organic Phase PVA",
volume = "15",
number = "5",
pages = "4441",
doi = "10.3390/su15054441"
}
Ivanović, M. M., Knežević, S., Radović, I., Kljajević, L. M., Mirković, M. M., Nenadović, M.,& Nenadović, S. S.. (2023). Preparation and Characterization of Geopolymers Based on Metakaolin with the Addition of Organic Phase PVA. in Sustainability, 15(5), 4441.
https://doi.org/10.3390/su15054441
Ivanović MM, Knežević S, Radović I, Kljajević LM, Mirković MM, Nenadović M, Nenadović SS. Preparation and Characterization of Geopolymers Based on Metakaolin with the Addition of Organic Phase PVA. in Sustainability. 2023;15(5):4441.
doi:10.3390/su15054441 .
Ivanović, Marija M., Knežević, Sanja, Radović, Ivona, Kljajević, Ljiljana M., Mirković, Miljana M., Nenadović, Miloš, Nenadović, Snežana S., "Preparation and Characterization of Geopolymers Based on Metakaolin with the Addition of Organic Phase PVA" in Sustainability, 15, no. 5 (2023):4441,
https://doi.org/10.3390/su15054441 . .

Structural Characterization of Geopolymers with the Addition of Eggshell Ash

Ivanović, Marija M.; Knežević, Sanja; Mirković, Miljana M.; Kljajević, Ljiljana M.; Bučevac, Dušan; Pavlović, Vladimir B.; Nenadović, Miloš

(2023)

TY  - JOUR
AU  - Ivanović, Marija M.
AU  - Knežević, Sanja
AU  - Mirković, Miljana M.
AU  - Kljajević, Ljiljana M.
AU  - Bučevac, Dušan
AU  - Pavlović, Vladimir B.
AU  - Nenadović, Miloš
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10741
AB  - It is well known that geopolymers are a new group of binder materials of alumosilicate origin. Geopolymers are made by the reaction of precursor aluminosilicate materials with alkaline activator solutions. The current research relates to a low-cost and eco-friendly procedure, suitable of being implemented in two easy steps. The first step is the production of a solid phase based on fly ash (Obrenovac, Serbia) and eggshell ash as waste materials rich in calcium. The second step is alkali activating the solid phase using an alkaline activator (a mixture of NaOH and Na2SiO3) and procedures in proper laboratory conditions. Four samples with different eggshell ash content were synthesized. The concentration of used NaOH was 12 mol dm−3. The structural properties of all investigated samples were analyzed by XRD (X-ray diffraction), DRIFT (diffuse reflectance infrared Fourier transform), SEM (scanning electron microscopy) and UV/Vis spectroscopy analysis. XRD determined the amorphous halo with the presence of quartz as the crystal phase in all of the investigated samples. These results were confirmed by DRIFT analysis. The morphology of the samples was determined by SEM analysis. UV/Vis showed that the material could be a potential adsorbent.
T2  - Sustainability
T1  - Structural Characterization of Geopolymers with the Addition of Eggshell Ash
VL  - 15
IS  - 6
SP  - 5419
DO  - 10.3390/su15065419
ER  - 
@article{
author = "Ivanović, Marija M. and Knežević, Sanja and Mirković, Miljana M. and Kljajević, Ljiljana M. and Bučevac, Dušan and Pavlović, Vladimir B. and Nenadović, Miloš",
year = "2023",
abstract = "It is well known that geopolymers are a new group of binder materials of alumosilicate origin. Geopolymers are made by the reaction of precursor aluminosilicate materials with alkaline activator solutions. The current research relates to a low-cost and eco-friendly procedure, suitable of being implemented in two easy steps. The first step is the production of a solid phase based on fly ash (Obrenovac, Serbia) and eggshell ash as waste materials rich in calcium. The second step is alkali activating the solid phase using an alkaline activator (a mixture of NaOH and Na2SiO3) and procedures in proper laboratory conditions. Four samples with different eggshell ash content were synthesized. The concentration of used NaOH was 12 mol dm−3. The structural properties of all investigated samples were analyzed by XRD (X-ray diffraction), DRIFT (diffuse reflectance infrared Fourier transform), SEM (scanning electron microscopy) and UV/Vis spectroscopy analysis. XRD determined the amorphous halo with the presence of quartz as the crystal phase in all of the investigated samples. These results were confirmed by DRIFT analysis. The morphology of the samples was determined by SEM analysis. UV/Vis showed that the material could be a potential adsorbent.",
journal = "Sustainability",
title = "Structural Characterization of Geopolymers with the Addition of Eggshell Ash",
volume = "15",
number = "6",
pages = "5419",
doi = "10.3390/su15065419"
}
Ivanović, M. M., Knežević, S., Mirković, M. M., Kljajević, L. M., Bučevac, D., Pavlović, V. B.,& Nenadović, M.. (2023). Structural Characterization of Geopolymers with the Addition of Eggshell Ash. in Sustainability, 15(6), 5419.
https://doi.org/10.3390/su15065419
Ivanović MM, Knežević S, Mirković MM, Kljajević LM, Bučevac D, Pavlović VB, Nenadović M. Structural Characterization of Geopolymers with the Addition of Eggshell Ash. in Sustainability. 2023;15(6):5419.
doi:10.3390/su15065419 .
Ivanović, Marija M., Knežević, Sanja, Mirković, Miljana M., Kljajević, Ljiljana M., Bučevac, Dušan, Pavlović, Vladimir B., Nenadović, Miloš, "Structural Characterization of Geopolymers with the Addition of Eggshell Ash" in Sustainability, 15, no. 6 (2023):5419,
https://doi.org/10.3390/su15065419 . .

Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors

Laban, Bojana B.; Lazarević-Pašti, Tamara; Veljović, Đorđe; Marković, Mirjana; Klekotka, Urszula

(2023)

TY  - JOUR
AU  - Laban, Bojana B.
AU  - Lazarević-Pašti, Tamara
AU  - Veljović, Đorđe
AU  - Marković, Mirjana
AU  - Klekotka, Urszula
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10740
AB  - The silver and gold L-methionine capped nanoparticles (Ag and Au @LM NPs) were analyzed as prospective acetylcholinesterase (AChE) inhibitors to test their potential in the treatment of cognitive impairment in depression and Alzheimer's disease. The stability of NPs, and their ability to inhibit AChE were studied by UV-Vis and FTIR spectrophotometry. At the same time, TEM and SEM measurements, DLS, and zeta potential measurements were employed in the structural characterization of NPs. Nearly spherical, negatively charged Ag and Au @LM NPs, with 17 nm and 31 nm in diameter, respectively, showed moderate inhibitory potential toward AChE in the given frame of investigated concentrations. For both NPs IC50 is not reached. Furthermore, the adsorption of enzyme molecules on the surface of Ag and Au @LM NPs was demonstrated. Hence, our assumption is that inhibition of AChE is caused by blockage of the enzyme‘s active site due to the steric hindrance of NPs.
T2  - European Journal of Inorganic Chemistry
T1  - Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors
SP  - e202200754
DO  - 10.1002/ejic.202200754
ER  - 
@article{
author = "Laban, Bojana B. and Lazarević-Pašti, Tamara and Veljović, Đorđe and Marković, Mirjana and Klekotka, Urszula",
year = "2023",
abstract = "The silver and gold L-methionine capped nanoparticles (Ag and Au @LM NPs) were analyzed as prospective acetylcholinesterase (AChE) inhibitors to test their potential in the treatment of cognitive impairment in depression and Alzheimer's disease. The stability of NPs, and their ability to inhibit AChE were studied by UV-Vis and FTIR spectrophotometry. At the same time, TEM and SEM measurements, DLS, and zeta potential measurements were employed in the structural characterization of NPs. Nearly spherical, negatively charged Ag and Au @LM NPs, with 17 nm and 31 nm in diameter, respectively, showed moderate inhibitory potential toward AChE in the given frame of investigated concentrations. For both NPs IC50 is not reached. Furthermore, the adsorption of enzyme molecules on the surface of Ag and Au @LM NPs was demonstrated. Hence, our assumption is that inhibition of AChE is caused by blockage of the enzyme‘s active site due to the steric hindrance of NPs.",
journal = "European Journal of Inorganic Chemistry",
title = "Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors",
pages = "e202200754",
doi = "10.1002/ejic.202200754"
}
Laban, B. B., Lazarević-Pašti, T., Veljović, Đ., Marković, M.,& Klekotka, U.. (2023). Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors. in European Journal of Inorganic Chemistry, e202200754.
https://doi.org/10.1002/ejic.202200754
Laban BB, Lazarević-Pašti T, Veljović Đ, Marković M, Klekotka U. Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors. in European Journal of Inorganic Chemistry. 2023;:e202200754.
doi:10.1002/ejic.202200754 .
Laban, Bojana B., Lazarević-Pašti, Tamara, Veljović, Đorđe, Marković, Mirjana, Klekotka, Urszula, "Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors" in European Journal of Inorganic Chemistry (2023):e202200754,
https://doi.org/10.1002/ejic.202200754 . .

Thermal decomposition kinetics of deep eutectic solvent (DES) based on choline chloride and magnesium chloride hexahydrate: New details on the reaction mechanism and enthalpy–entropy compensation (EEC)

Janković, Bojan Ž.; Manić, Nebojša; Perović, Ivana M.; Vujković, Milica; Zdolšek, Nikola

(2023)

TY  - JOUR
AU  - Janković, Bojan Ž.
AU  - Manić, Nebojša
AU  - Perović, Ivana M.
AU  - Vujković, Milica
AU  - Zdolšek, Nikola
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10739
AB  - In recent years, deep eutectic solvents (DESs) have attracted considerable attention, and they have been applied in many fields, such as dissolution and separation, electrochemistry, materials preparation, reaction, and catalysis. In this paper, a detailed thermal decomposition mechanism of DES-type II (consisting choline chloride (ChCl) and magnesium chloride hexahydrate (MgCl2·6H2O) in a molar ratio 2:1 (MgCl2·6H2O-[Ch]Cl)) was explained, using thermal analysis techniques. Physicochemical clarification of overall thermal decomposition mechanism and the influence of enthalpy–entropy compensation (EEC) on reactions mechanism emerging are presented for the first time, in favor of this DES type. In the kinetic analysis of the decomposition process, two approaches were used: model-free (inverse) and model-based (direct) methods. It was found that thermodynamic principles in the form of EEC are the source of kinetic compensation effect (KCE) during MgCl2·6H2O-[Ch]Cl thermal decomposition, as a consequence of the effects of molecular interactions. Key phenomenon in the complex multiple step process represents a parallel dehydration steps of MgCl2·6H2O in DES, leading to formation of intermediates, such as [MgCl1(H2O)5]1+ and [MgCl2(H2O)4]. It was established that formation of final products (Mg(OH)2 and MgOHCl) requires a higher expenditure of energy to overcome a high potential barrier, where reaction system compensates this energy via hydrogen bonding disruption. This was confirmed by the identification of a specific ‘oscillator’, flagged as Hsingle bondOsingle bondH···Cl hydrogen bond donating system of the energy (“heat bath”). All kinetic parameters and mechanisms of individual reaction steps were confirmed by numerical optimization of the process and modulated dynamic predictions.
T2  - Journal of Molecular Liquids
T1  - Thermal decomposition kinetics of deep eutectic solvent (DES) based on choline chloride and magnesium chloride hexahydrate: New details on the reaction mechanism and enthalpy–entropy compensation (EEC)
VL  - 374
SP  - 121274
DO  - 10.1016/j.molliq.2023.121274
ER  - 
@article{
author = "Janković, Bojan Ž. and Manić, Nebojša and Perović, Ivana M. and Vujković, Milica and Zdolšek, Nikola",
year = "2023",
abstract = "In recent years, deep eutectic solvents (DESs) have attracted considerable attention, and they have been applied in many fields, such as dissolution and separation, electrochemistry, materials preparation, reaction, and catalysis. In this paper, a detailed thermal decomposition mechanism of DES-type II (consisting choline chloride (ChCl) and magnesium chloride hexahydrate (MgCl2·6H2O) in a molar ratio 2:1 (MgCl2·6H2O-[Ch]Cl)) was explained, using thermal analysis techniques. Physicochemical clarification of overall thermal decomposition mechanism and the influence of enthalpy–entropy compensation (EEC) on reactions mechanism emerging are presented for the first time, in favor of this DES type. In the kinetic analysis of the decomposition process, two approaches were used: model-free (inverse) and model-based (direct) methods. It was found that thermodynamic principles in the form of EEC are the source of kinetic compensation effect (KCE) during MgCl2·6H2O-[Ch]Cl thermal decomposition, as a consequence of the effects of molecular interactions. Key phenomenon in the complex multiple step process represents a parallel dehydration steps of MgCl2·6H2O in DES, leading to formation of intermediates, such as [MgCl1(H2O)5]1+ and [MgCl2(H2O)4]. It was established that formation of final products (Mg(OH)2 and MgOHCl) requires a higher expenditure of energy to overcome a high potential barrier, where reaction system compensates this energy via hydrogen bonding disruption. This was confirmed by the identification of a specific ‘oscillator’, flagged as Hsingle bondOsingle bondH···Cl hydrogen bond donating system of the energy (“heat bath”). All kinetic parameters and mechanisms of individual reaction steps were confirmed by numerical optimization of the process and modulated dynamic predictions.",
journal = "Journal of Molecular Liquids",
title = "Thermal decomposition kinetics of deep eutectic solvent (DES) based on choline chloride and magnesium chloride hexahydrate: New details on the reaction mechanism and enthalpy–entropy compensation (EEC)",
volume = "374",
pages = "121274",
doi = "10.1016/j.molliq.2023.121274"
}
Janković, B. Ž., Manić, N., Perović, I. M., Vujković, M.,& Zdolšek, N.. (2023). Thermal decomposition kinetics of deep eutectic solvent (DES) based on choline chloride and magnesium chloride hexahydrate: New details on the reaction mechanism and enthalpy–entropy compensation (EEC). in Journal of Molecular Liquids, 374, 121274.
https://doi.org/10.1016/j.molliq.2023.121274
Janković BŽ, Manić N, Perović IM, Vujković M, Zdolšek N. Thermal decomposition kinetics of deep eutectic solvent (DES) based on choline chloride and magnesium chloride hexahydrate: New details on the reaction mechanism and enthalpy–entropy compensation (EEC). in Journal of Molecular Liquids. 2023;374:121274.
doi:10.1016/j.molliq.2023.121274 .
Janković, Bojan Ž., Manić, Nebojša, Perović, Ivana M., Vujković, Milica, Zdolšek, Nikola, "Thermal decomposition kinetics of deep eutectic solvent (DES) based on choline chloride and magnesium chloride hexahydrate: New details on the reaction mechanism and enthalpy–entropy compensation (EEC)" in Journal of Molecular Liquids, 374 (2023):121274,
https://doi.org/10.1016/j.molliq.2023.121274 . .
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