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Amperometric determination of cholesterol using cholesterol oxidase immobilized on Pt,Ru-C nanocomposite and an ionic liquid-modified carbon paste electrode

Mutić, Sanja; Stanković, Dalibor; Konya, Z.; Anojčić, J.

TY  - CONF
AU  - Mutić, Sanja
AU  - Stanković, Dalibor
AU  - Konya, Z.
AU  - Anojčić, J.
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11962
AB  - Cholesterol as very important biomolecule is the precursor of many biologically significant compounds which give strength and flexibility to the biological membranes. It is also a crucial component in lipoproteins, and has an important role to transport hydrophobic molecules in hydrophilic media such as blood [1, 2]. The analytical performance of carbon paste electrodes (CPE) bulk modified with ionic liquid 1-allyl-3-methylimidazolium dicyanamide ([AMIM][DCA]), and surface modified with platinum on graphitized carbon (Pt-C) or platinum-ruthenium alloy on graphitized carbon (Pt,Ru-C) for analysis of hydrogen peroxide (H 2O2) were compared. The prepared working electrodes were characterized using scanning electron microscopy–energydispersive X-ray spectrometry, together with electrochemical impedance spectroscopic, cyclic voltammetric, and amperometric techniques. After method optimization, an enzyme cholesterol oxidase (ChOx) was immobilized on the surface of Pt,Ru-C/IL-CPE by Nafion®. The improved cholesterol amperometric determination was achieved in phosphate buffer solution pH 7.50 at a working potential of 0.60 V. Under the optimized experimental conditions, a linear relationship between oxidation current and cholesterol concentration was in the concentration range from 0.31 to 2.46 µM, with an estimated detection limit of 0.13 µM and relative standard deviation (RSD) below 4.2%. The optimized amperometric method in combination with the developed ChOx/Pt,Ru-C/IL-CPE biosensor showed good repeatability and high selectivity towards cholesterol biosensing despite the presence of possible interferences. The ChOx/Pt,Ru-C/IL-CPE was tested for the determination of the free cholesterol, by its enzymatic reaction product H 2O2, in a human blood serum sample. The percentage recovery ranged from 99.08 to 102.81%, while RSD was below 2.0% for untreated, as well as for spiked human blood serum sample.
PB  - University of Belgrade : Faculty of Chemistry
C3  - YISAC 2023 : 28th Young Investigators' Seminar on Analytical Chemistry : the book of abstracts
T1  - Amperometric determination of cholesterol using cholesterol oxidase immobilized on Pt,Ru-C nanocomposite and an ionic liquid-modified carbon paste electrode
SP  - 53
EP  - 53
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11962
ER  - 
@conference{
author = "Mutić, Sanja and Stanković, Dalibor and Konya, Z. and Anojčić, J.",
abstract = "Cholesterol as very important biomolecule is the precursor of many biologically significant compounds which give strength and flexibility to the biological membranes. It is also a crucial component in lipoproteins, and has an important role to transport hydrophobic molecules in hydrophilic media such as blood [1, 2]. The analytical performance of carbon paste electrodes (CPE) bulk modified with ionic liquid 1-allyl-3-methylimidazolium dicyanamide ([AMIM][DCA]), and surface modified with platinum on graphitized carbon (Pt-C) or platinum-ruthenium alloy on graphitized carbon (Pt,Ru-C) for analysis of hydrogen peroxide (H 2O2) were compared. The prepared working electrodes were characterized using scanning electron microscopy–energydispersive X-ray spectrometry, together with electrochemical impedance spectroscopic, cyclic voltammetric, and amperometric techniques. After method optimization, an enzyme cholesterol oxidase (ChOx) was immobilized on the surface of Pt,Ru-C/IL-CPE by Nafion®. The improved cholesterol amperometric determination was achieved in phosphate buffer solution pH 7.50 at a working potential of 0.60 V. Under the optimized experimental conditions, a linear relationship between oxidation current and cholesterol concentration was in the concentration range from 0.31 to 2.46 µM, with an estimated detection limit of 0.13 µM and relative standard deviation (RSD) below 4.2%. The optimized amperometric method in combination with the developed ChOx/Pt,Ru-C/IL-CPE biosensor showed good repeatability and high selectivity towards cholesterol biosensing despite the presence of possible interferences. The ChOx/Pt,Ru-C/IL-CPE was tested for the determination of the free cholesterol, by its enzymatic reaction product H 2O2, in a human blood serum sample. The percentage recovery ranged from 99.08 to 102.81%, while RSD was below 2.0% for untreated, as well as for spiked human blood serum sample.",
publisher = "University of Belgrade : Faculty of Chemistry",
journal = "YISAC 2023 : 28th Young Investigators' Seminar on Analytical Chemistry : the book of abstracts",
title = "Amperometric determination of cholesterol using cholesterol oxidase immobilized on Pt,Ru-C nanocomposite and an ionic liquid-modified carbon paste electrode",
pages = "53-53",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11962"
}
Mutić, S., Stanković, D., Konya, Z.,& Anojčić, J..Amperometric determination of cholesterol using cholesterol oxidase immobilized on Pt,Ru-C nanocomposite and an ionic liquid-modified carbon paste electrode. in YISAC 2023 : 28th Young Investigators' Seminar on Analytical Chemistry : the book of abstracts
University of Belgrade : Faculty of Chemistry., 53-53.
https://hdl.handle.net/21.15107/rcub_vinar_11962
Mutić S, Stanković D, Konya Z, Anojčić J. Amperometric determination of cholesterol using cholesterol oxidase immobilized on Pt,Ru-C nanocomposite and an ionic liquid-modified carbon paste electrode. in YISAC 2023 : 28th Young Investigators' Seminar on Analytical Chemistry : the book of abstracts.:53-53.
https://hdl.handle.net/21.15107/rcub_vinar_11962 .
Mutić, Sanja, Stanković, Dalibor, Konya, Z., Anojčić, J., "Amperometric determination of cholesterol using cholesterol oxidase immobilized on Pt,Ru-C nanocomposite and an ionic liquid-modified carbon paste electrode" in YISAC 2023 : 28th Young Investigators' Seminar on Analytical Chemistry : the book of abstracts:53-53,
https://hdl.handle.net/21.15107/rcub_vinar_11962 .

Step by step optimization of luminescence thermometry in MgTiO3:Cr3+, Nd3+@SiO2 nanoparticles towards bioapplications

Piotrowski, Wojciech M.; Szymczak, Maja; Rodríguez, Emma Martín; Marin, Riccardo; Henklewska, Marta; Poźniak, Błażej; Dramićanin, Miroslav; Marciniak, Lukasz

(2024)

TY  - JOUR
AU  - Piotrowski, Wojciech M.
AU  - Szymczak, Maja
AU  - Rodríguez, Emma Martín
AU  - Marin, Riccardo
AU  - Henklewska, Marta
AU  - Poźniak, Błażej
AU  - Dramićanin, Miroslav
AU  - Marciniak, Lukasz
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11929
AB  - The increasing popularity of luminescent nanothermometry in recent years can be attributed to its application potential in biomedicine. In response to this need, we describe a biocompatible bimodal luminescent thermometer that operates in ratiometric and luminescence lifetime modes based on particles of MgTiO3:Cr3+,Nd3+@SiO2. The introduction of Cr3+ and Nd3+ dopants enabled the luminescence of Ti3+ ions to be observed, and the difference in the thermal quenching rates of Cr3+ (4T2→4A2), Ti3+ (2T2→2E) and Nd3+ (4F3/2 → 4I11/2) ions enabled the ratiometric thermometers. The highest sensitivity reaching SR = 1.00%K−1 was obtained for MgTiO3:0.1 % Cr3+, 0.1 % Nd3+ at 203 K. The shortening of the lifetime of the 4T2 level of Cr3+ ions associated with its thermal depopulation allows to develop a lifetime-based thermometer with a relative sensitivity reaching 0.85–1.18%K−1 in the physiological temperature range. The deposition of a SiO2 shell on a MgTiO3:Cr3+,Nd3+ did not introduce significant changes in the shape of the emission spectrum and slightly elongates the lifetime by reducing the probability of surface-related nonradiative processes. More importantly, the thermometric performance of this luminescence thermometer was preserved. The low cytotoxicity of the obtained materials underlines their potential in bioapplications of the described luminescent thermometers.
T2  - Materials Chemistry and Physics
T1  - Step by step optimization of luminescence thermometry in MgTiO3:Cr3+, Nd3+@SiO2 nanoparticles towards bioapplications
VL  - 312
SP  - 128623
DO  - 10.1016/j.matchemphys.2023.128623
ER  - 
@article{
author = "Piotrowski, Wojciech M. and Szymczak, Maja and Rodríguez, Emma Martín and Marin, Riccardo and Henklewska, Marta and Poźniak, Błażej and Dramićanin, Miroslav and Marciniak, Lukasz",
year = "2024",
abstract = "The increasing popularity of luminescent nanothermometry in recent years can be attributed to its application potential in biomedicine. In response to this need, we describe a biocompatible bimodal luminescent thermometer that operates in ratiometric and luminescence lifetime modes based on particles of MgTiO3:Cr3+,Nd3+@SiO2. The introduction of Cr3+ and Nd3+ dopants enabled the luminescence of Ti3+ ions to be observed, and the difference in the thermal quenching rates of Cr3+ (4T2→4A2), Ti3+ (2T2→2E) and Nd3+ (4F3/2 → 4I11/2) ions enabled the ratiometric thermometers. The highest sensitivity reaching SR = 1.00%K−1 was obtained for MgTiO3:0.1 % Cr3+, 0.1 % Nd3+ at 203 K. The shortening of the lifetime of the 4T2 level of Cr3+ ions associated with its thermal depopulation allows to develop a lifetime-based thermometer with a relative sensitivity reaching 0.85–1.18%K−1 in the physiological temperature range. The deposition of a SiO2 shell on a MgTiO3:Cr3+,Nd3+ did not introduce significant changes in the shape of the emission spectrum and slightly elongates the lifetime by reducing the probability of surface-related nonradiative processes. More importantly, the thermometric performance of this luminescence thermometer was preserved. The low cytotoxicity of the obtained materials underlines their potential in bioapplications of the described luminescent thermometers.",
journal = "Materials Chemistry and Physics",
title = "Step by step optimization of luminescence thermometry in MgTiO3:Cr3+, Nd3+@SiO2 nanoparticles towards bioapplications",
volume = "312",
pages = "128623",
doi = "10.1016/j.matchemphys.2023.128623"
}
Piotrowski, W. M., Szymczak, M., Rodríguez, E. M., Marin, R., Henklewska, M., Poźniak, B., Dramićanin, M.,& Marciniak, L.. (2024). Step by step optimization of luminescence thermometry in MgTiO3:Cr3+, Nd3+@SiO2 nanoparticles towards bioapplications. in Materials Chemistry and Physics, 312, 128623.
https://doi.org/10.1016/j.matchemphys.2023.128623
Piotrowski WM, Szymczak M, Rodríguez EM, Marin R, Henklewska M, Poźniak B, Dramićanin M, Marciniak L. Step by step optimization of luminescence thermometry in MgTiO3:Cr3+, Nd3+@SiO2 nanoparticles towards bioapplications. in Materials Chemistry and Physics. 2024;312:128623.
doi:10.1016/j.matchemphys.2023.128623 .
Piotrowski, Wojciech M., Szymczak, Maja, Rodríguez, Emma Martín, Marin, Riccardo, Henklewska, Marta, Poźniak, Błażej, Dramićanin, Miroslav, Marciniak, Lukasz, "Step by step optimization of luminescence thermometry in MgTiO3:Cr3+, Nd3+@SiO2 nanoparticles towards bioapplications" in Materials Chemistry and Physics, 312 (2024):128623,
https://doi.org/10.1016/j.matchemphys.2023.128623 . .

Employing carbon quantum dots to combat cytomegalovirus

Bulat, Tanja; Zmejkoski, Danica; Marković, Zoran; Satzinger, Melissa; Kovač, Janez; Strobl, Birgit; Milivojević, Dušan; Todorović Marković, Biljana

(2024)

TY  - JOUR
AU  - Bulat, Tanja
AU  - Zmejkoski, Danica
AU  - Marković, Zoran
AU  - Satzinger, Melissa
AU  - Kovač, Janez
AU  - Strobl, Birgit
AU  - Milivojević, Dušan
AU  - Todorović Marković, Biljana
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11831
AB  - Carbon quantum dots (CQDs) are well known as a promising therapeutic agent due to their excellent pro-oxidant, antioxidant, antibacterial and anticancer properties under visible light irradiation. This material is easy to produce by several bottom-up or top-down methods. In this study, we used citric acid as starting precursor to synthesize aqueous carbon quantum dots dispersion by pyrolysis at 210 ◦C. Atomic force microscopy and XPS analyses revealed that CQDs synthesized are quasi-spherical with typical diameter of 9 nm and lots of C–O and C––O functional groups distributed over the basal plane and edges of the dots. Here, we investigated the antiviral properties of CQDs against cytomegalovirus (CMV). The pre-treatment with CQDs upregulates interferonstimulated genes (ISG), resulting in better virus control. Cellular defence against cytomegalovirus of CQDs pre-treated cells is increased in a dose-dependent manner. Our results reveal high biocompatibility and potent in vitro antiviral properties of CQDs.
T2  - Materials Chemistry and Physics
T1  - Employing carbon quantum dots to combat cytomegalovirus
VL  - 311
SP  - 128495
DO  - 10.1016/j.matchemphys.2023.128495
ER  - 
@article{
author = "Bulat, Tanja and Zmejkoski, Danica and Marković, Zoran and Satzinger, Melissa and Kovač, Janez and Strobl, Birgit and Milivojević, Dušan and Todorović Marković, Biljana",
year = "2024",
abstract = "Carbon quantum dots (CQDs) are well known as a promising therapeutic agent due to their excellent pro-oxidant, antioxidant, antibacterial and anticancer properties under visible light irradiation. This material is easy to produce by several bottom-up or top-down methods. In this study, we used citric acid as starting precursor to synthesize aqueous carbon quantum dots dispersion by pyrolysis at 210 ◦C. Atomic force microscopy and XPS analyses revealed that CQDs synthesized are quasi-spherical with typical diameter of 9 nm and lots of C–O and C––O functional groups distributed over the basal plane and edges of the dots. Here, we investigated the antiviral properties of CQDs against cytomegalovirus (CMV). The pre-treatment with CQDs upregulates interferonstimulated genes (ISG), resulting in better virus control. Cellular defence against cytomegalovirus of CQDs pre-treated cells is increased in a dose-dependent manner. Our results reveal high biocompatibility and potent in vitro antiviral properties of CQDs.",
journal = "Materials Chemistry and Physics",
title = "Employing carbon quantum dots to combat cytomegalovirus",
volume = "311",
pages = "128495",
doi = "10.1016/j.matchemphys.2023.128495"
}
Bulat, T., Zmejkoski, D., Marković, Z., Satzinger, M., Kovač, J., Strobl, B., Milivojević, D.,& Todorović Marković, B.. (2024). Employing carbon quantum dots to combat cytomegalovirus. in Materials Chemistry and Physics, 311, 128495.
https://doi.org/10.1016/j.matchemphys.2023.128495
Bulat T, Zmejkoski D, Marković Z, Satzinger M, Kovač J, Strobl B, Milivojević D, Todorović Marković B. Employing carbon quantum dots to combat cytomegalovirus. in Materials Chemistry and Physics. 2024;311:128495.
doi:10.1016/j.matchemphys.2023.128495 .
Bulat, Tanja, Zmejkoski, Danica, Marković, Zoran, Satzinger, Melissa, Kovač, Janez, Strobl, Birgit, Milivojević, Dušan, Todorović Marković, Biljana, "Employing carbon quantum dots to combat cytomegalovirus" in Materials Chemistry and Physics, 311 (2024):128495,
https://doi.org/10.1016/j.matchemphys.2023.128495 . .

Tuning phase and photoluminescent properties of ZrO2:Eu3+ coatings formed by plasma electrolytic oxidation and Judd-Ofelt analysis of composite materials

Ćirić, Aleksandar; Stojadinović, Stevan

(2024)

TY  - JOUR
AU  - Ćirić, Aleksandar
AU  - Stojadinović, Stevan
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11828
AB  - Eu3+ doped Zirconia coatings were synthesized by the electrochemical plasma electrolytic oxidation method in only 8 min from the pure zirconium substrate. The phase constitution from pure monoclinic to pure tetragonal and exactly in between was achieved by using different concentrations of Na3PO4 and NaAlO2 electrolytes. The complex emission spectra composed of Eu2+, Eu3+, and ZrO2 defect emission greatly depend on the excitation wavelength and phase constitution. Eu3+ photoluminescence properties depend on the phase, which is reflected by the different Stark splitting and different intensities of transitions. Thus, both phase and photoluminescent properties of ZrO2 coatings are fine-tuneable. Judd-Ofelt analysis was performed from the emission and excitation spectra, showing that all 3 intensity parameters depend linearly on the phase constitution, being largest in the pure monoclinic phase. The mixed phase has Judd-Ofelt parameters between those in pure phases. Eu3+ has 2.45 times more preference to get incorporated into the tetragonal than in the monoclinic phase in the mixed phase samples. The general equation for Judd-Ofelt parameters in a compound with mixed constituents and probability of incorporation is introduced, allowing also for a prediction of the spectrum shape based on the Judd-Ofelt parameters of pure-phase compounds. Python software code for estimating the percent of incorporation by multiple linear regression model is also provided.
T2  - Journal of Luminescence
T1  - Tuning phase and photoluminescent properties of ZrO2:Eu3+ coatings formed by plasma electrolytic oxidation and Judd-Ofelt analysis of composite materials
VL  - 266
SP  - 120268
DO  - 10.1016/j.jlumin.2023.120268
ER  - 
@article{
author = "Ćirić, Aleksandar and Stojadinović, Stevan",
year = "2024",
abstract = "Eu3+ doped Zirconia coatings were synthesized by the electrochemical plasma electrolytic oxidation method in only 8 min from the pure zirconium substrate. The phase constitution from pure monoclinic to pure tetragonal and exactly in between was achieved by using different concentrations of Na3PO4 and NaAlO2 electrolytes. The complex emission spectra composed of Eu2+, Eu3+, and ZrO2 defect emission greatly depend on the excitation wavelength and phase constitution. Eu3+ photoluminescence properties depend on the phase, which is reflected by the different Stark splitting and different intensities of transitions. Thus, both phase and photoluminescent properties of ZrO2 coatings are fine-tuneable. Judd-Ofelt analysis was performed from the emission and excitation spectra, showing that all 3 intensity parameters depend linearly on the phase constitution, being largest in the pure monoclinic phase. The mixed phase has Judd-Ofelt parameters between those in pure phases. Eu3+ has 2.45 times more preference to get incorporated into the tetragonal than in the monoclinic phase in the mixed phase samples. The general equation for Judd-Ofelt parameters in a compound with mixed constituents and probability of incorporation is introduced, allowing also for a prediction of the spectrum shape based on the Judd-Ofelt parameters of pure-phase compounds. Python software code for estimating the percent of incorporation by multiple linear regression model is also provided.",
journal = "Journal of Luminescence",
title = "Tuning phase and photoluminescent properties of ZrO2:Eu3+ coatings formed by plasma electrolytic oxidation and Judd-Ofelt analysis of composite materials",
volume = "266",
pages = "120268",
doi = "10.1016/j.jlumin.2023.120268"
}
Ćirić, A.,& Stojadinović, S.. (2024). Tuning phase and photoluminescent properties of ZrO2:Eu3+ coatings formed by plasma electrolytic oxidation and Judd-Ofelt analysis of composite materials. in Journal of Luminescence, 266, 120268.
https://doi.org/10.1016/j.jlumin.2023.120268
Ćirić A, Stojadinović S. Tuning phase and photoluminescent properties of ZrO2:Eu3+ coatings formed by plasma electrolytic oxidation and Judd-Ofelt analysis of composite materials. in Journal of Luminescence. 2024;266:120268.
doi:10.1016/j.jlumin.2023.120268 .
Ćirić, Aleksandar, Stojadinović, Stevan, "Tuning phase and photoluminescent properties of ZrO2:Eu3+ coatings formed by plasma electrolytic oxidation and Judd-Ofelt analysis of composite materials" in Journal of Luminescence, 266 (2024):120268,
https://doi.org/10.1016/j.jlumin.2023.120268 . .

First-principles calculations of the electronic structure and mechanical properties of non-doped and Cr3+-Doped K2LiAlF6 under pressure

Umar, Zafari; Kurboniyon, Mekhrdod S.; Khyzhun, Oleg; Yamamoto, Tomoyuki; Ma, Chong-Geng; Brik, Mikhail G.; Piasecki, Michal

(2024)

TY  - JOUR
AU  - Umar, Zafari
AU  - Kurboniyon, Mekhrdod S.
AU  - Khyzhun, Oleg
AU  - Yamamoto, Tomoyuki
AU  - Ma, Chong-Geng
AU  - Brik, Mikhail G.
AU  - Piasecki, Michal
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11826
AB  - We report on the results of the first principles calculations based on density functional theory (DFT) of the electronic structure and mechanical properties of K2LiAlF6, both non-doped and doped with Cr3+ ions. The densities of states of K2LiAlF6 and the K2LiAlF6:Cr3+ phosphor as well as the crystal-field strength 10Dq, the Cr3+ 2E→4A2 emission energy, elastic constants, bulk and shear moduli, sound velocities and Debye temperature as functions of hydrostatic pressure ranging from 0 up to 40 GPa were calculated. The present DFT calculations indicate that, the band gap of non-doped K2LiAlF6 increases quadratically with increasing pressure. Further, the crystal field strength 10Dq and the 2E→4A2 emission energy, the Debye temperature, sound velocities and shear moduli of Cr-doped K2LiAlF6 increase with increasing pressure, while the 2E→4A2 emission energy becomes red-shifted, which indicates potential applicability of the studied system for pressure sensing. Such calculations for the title system were performed for the first time; the obtained results provide a firm basis for a deeper understanding of physical properties of both neat and doped functional materials.
T2  - Journal of Luminescence
T1  - First-principles calculations of the electronic structure and mechanical properties of non-doped and Cr3+-Doped K2LiAlF6 under pressure
VL  - 266
SP  - 120278
DO  - 10.1016/j.jlumin.2023.120278
ER  - 
@article{
author = "Umar, Zafari and Kurboniyon, Mekhrdod S. and Khyzhun, Oleg and Yamamoto, Tomoyuki and Ma, Chong-Geng and Brik, Mikhail G. and Piasecki, Michal",
year = "2024",
abstract = "We report on the results of the first principles calculations based on density functional theory (DFT) of the electronic structure and mechanical properties of K2LiAlF6, both non-doped and doped with Cr3+ ions. The densities of states of K2LiAlF6 and the K2LiAlF6:Cr3+ phosphor as well as the crystal-field strength 10Dq, the Cr3+ 2E→4A2 emission energy, elastic constants, bulk and shear moduli, sound velocities and Debye temperature as functions of hydrostatic pressure ranging from 0 up to 40 GPa were calculated. The present DFT calculations indicate that, the band gap of non-doped K2LiAlF6 increases quadratically with increasing pressure. Further, the crystal field strength 10Dq and the 2E→4A2 emission energy, the Debye temperature, sound velocities and shear moduli of Cr-doped K2LiAlF6 increase with increasing pressure, while the 2E→4A2 emission energy becomes red-shifted, which indicates potential applicability of the studied system for pressure sensing. Such calculations for the title system were performed for the first time; the obtained results provide a firm basis for a deeper understanding of physical properties of both neat and doped functional materials.",
journal = "Journal of Luminescence",
title = "First-principles calculations of the electronic structure and mechanical properties of non-doped and Cr3+-Doped K2LiAlF6 under pressure",
volume = "266",
pages = "120278",
doi = "10.1016/j.jlumin.2023.120278"
}
Umar, Z., Kurboniyon, M. S., Khyzhun, O., Yamamoto, T., Ma, C., Brik, M. G.,& Piasecki, M.. (2024). First-principles calculations of the electronic structure and mechanical properties of non-doped and Cr3+-Doped K2LiAlF6 under pressure. in Journal of Luminescence, 266, 120278.
https://doi.org/10.1016/j.jlumin.2023.120278
Umar Z, Kurboniyon MS, Khyzhun O, Yamamoto T, Ma C, Brik MG, Piasecki M. First-principles calculations of the electronic structure and mechanical properties of non-doped and Cr3+-Doped K2LiAlF6 under pressure. in Journal of Luminescence. 2024;266:120278.
doi:10.1016/j.jlumin.2023.120278 .
Umar, Zafari, Kurboniyon, Mekhrdod S., Khyzhun, Oleg, Yamamoto, Tomoyuki, Ma, Chong-Geng, Brik, Mikhail G., Piasecki, Michal, "First-principles calculations of the electronic structure and mechanical properties of non-doped and Cr3+-Doped K2LiAlF6 under pressure" in Journal of Luminescence, 266 (2024):120278,
https://doi.org/10.1016/j.jlumin.2023.120278 . .

LIBS Hydrogen Isotopes Detection: Significance in Nuclear/Fusion Technology

Trtica, Milan; Savović, Jelena; Kuzmanović, M.; Ranković, D.; Stašić, Jelena

(2024)

TY  - JOUR
AU  - Trtica, Milan
AU  - Savović, Jelena
AU  - Kuzmanović, M.
AU  - Ranković, D.
AU  - Stašić, Jelena
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12052
AB  - The aspect of the detection of hydrogen isotopes in nuclear materials was analyzed in this review. Particular attention was paid to the spectroscopic methods for the detection of hydrogen isotopes in fusion reactor materials since their presence can induce severe problems in terms of material degradation and shortening of its lifetime. The main focus is on laser-induced breakdown spectroscopy, an optical emission method that is efficient, reliable, and fast. Recent results obtained at the VINCA Institute will also be presented.
T2  - Journal of Applied Spectroscopy
T1  - LIBS Hydrogen Isotopes Detection: Significance in Nuclear/Fusion Technology
VL  - 90
IS  - InPress
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12052
ER  - 
@article{
author = "Trtica, Milan and Savović, Jelena and Kuzmanović, M. and Ranković, D. and Stašić, Jelena",
year = "2024",
abstract = "The aspect of the detection of hydrogen isotopes in nuclear materials was analyzed in this review. Particular attention was paid to the spectroscopic methods for the detection of hydrogen isotopes in fusion reactor materials since their presence can induce severe problems in terms of material degradation and shortening of its lifetime. The main focus is on laser-induced breakdown spectroscopy, an optical emission method that is efficient, reliable, and fast. Recent results obtained at the VINCA Institute will also be presented.",
journal = "Journal of Applied Spectroscopy",
title = "LIBS Hydrogen Isotopes Detection: Significance in Nuclear/Fusion Technology",
volume = "90",
number = "InPress",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12052"
}
Trtica, M., Savović, J., Kuzmanović, M., Ranković, D.,& Stašić, J.. (2024). LIBS Hydrogen Isotopes Detection: Significance in Nuclear/Fusion Technology. in Journal of Applied Spectroscopy, 90(InPress).
https://hdl.handle.net/21.15107/rcub_vinar_12052
Trtica M, Savović J, Kuzmanović M, Ranković D, Stašić J. LIBS Hydrogen Isotopes Detection: Significance in Nuclear/Fusion Technology. in Journal of Applied Spectroscopy. 2024;90(InPress).
https://hdl.handle.net/21.15107/rcub_vinar_12052 .
Trtica, Milan, Savović, Jelena, Kuzmanović, M., Ranković, D., Stašić, Jelena, "LIBS Hydrogen Isotopes Detection: Significance in Nuclear/Fusion Technology" in Journal of Applied Spectroscopy, 90, no. InPress (2024),
https://hdl.handle.net/21.15107/rcub_vinar_12052 .

Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal

Katnić, Đurica B.; Porobić, Slavica; Vujčić, Ivica; Kojić, Marija; Lazarević-Pašti, Tamara; Milanković, Vedran; Marinović-Cincović, Milena; Živojinović, Dragana Z.

(2024)

TY  - JOUR
AU  - Katnić, Đurica B.
AU  - Porobić, Slavica
AU  - Vujčić, Ivica
AU  - Kojić, Marija
AU  - Lazarević-Pašti, Tamara
AU  - Milanković, Vedran
AU  - Marinović-Cincović, Milena
AU  - Živojinović, Dragana Z.
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11863
AB  - Irradiated fig pomace pyrochar (IrrPyrFP) is noteworthy as a novel sterilized low-cost sorbent of BTEX, pesticides, and Pb2+ ions. It was produced by applying pyrolysis treatment followed by gamma irradiation modification in order to obtain a highly efficient and sterile sorbent. The characterization of fig pomace before and after pyrolysis, as well as before and after irradiation of the obtained pyrochar, was done using SEM, FTIR, and elemental analysis, while its sorption ability was tested through the removal of examined pollutants by batch sorption experiments. The obtained results suggest that IrrPyrFP could play a significant role in the control of environmental pollutants, as indicated by the maximum adsorption capacities: 42 mg g−1 for BTEX, 0.625 mg g−1 for malathion, 0.495 mg g−1 for chlorpyrifos and 255 mg g−1 for Pb2+. A kinetic study showed that the removal process by IrrPyrFP mainly follows pseudo 2nd kinetics order, while the sorption equilibriums were estimated using the Langmuir and Freundlich model. Overall, the findings of this work suggest that pyrolysis and activation by irradiation of waste biomass is a promising way to produce sterile efficient sorbents for waste-water treatment based on green chemistry. Additionally, the demonstrated application of fig pomace promotes the potential of using this biomass for continual and economical waste management in the rising fig industry.
T2  - Radiation Physics and Chemistry
T1  - Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal
VL  - 214
SP  - 111277
DO  - 10.1016/j.radphyschem.2023.111277
ER  - 
@article{
author = "Katnić, Đurica B. and Porobić, Slavica and Vujčić, Ivica and Kojić, Marija and Lazarević-Pašti, Tamara and Milanković, Vedran and Marinović-Cincović, Milena and Živojinović, Dragana Z.",
year = "2024",
abstract = "Irradiated fig pomace pyrochar (IrrPyrFP) is noteworthy as a novel sterilized low-cost sorbent of BTEX, pesticides, and Pb2+ ions. It was produced by applying pyrolysis treatment followed by gamma irradiation modification in order to obtain a highly efficient and sterile sorbent. The characterization of fig pomace before and after pyrolysis, as well as before and after irradiation of the obtained pyrochar, was done using SEM, FTIR, and elemental analysis, while its sorption ability was tested through the removal of examined pollutants by batch sorption experiments. The obtained results suggest that IrrPyrFP could play a significant role in the control of environmental pollutants, as indicated by the maximum adsorption capacities: 42 mg g−1 for BTEX, 0.625 mg g−1 for malathion, 0.495 mg g−1 for chlorpyrifos and 255 mg g−1 for Pb2+. A kinetic study showed that the removal process by IrrPyrFP mainly follows pseudo 2nd kinetics order, while the sorption equilibriums were estimated using the Langmuir and Freundlich model. Overall, the findings of this work suggest that pyrolysis and activation by irradiation of waste biomass is a promising way to produce sterile efficient sorbents for waste-water treatment based on green chemistry. Additionally, the demonstrated application of fig pomace promotes the potential of using this biomass for continual and economical waste management in the rising fig industry.",
journal = "Radiation Physics and Chemistry",
title = "Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal",
volume = "214",
pages = "111277",
doi = "10.1016/j.radphyschem.2023.111277"
}
Katnić, Đ. B., Porobić, S., Vujčić, I., Kojić, M., Lazarević-Pašti, T., Milanković, V., Marinović-Cincović, M.,& Živojinović, D. Z.. (2024). Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal. in Radiation Physics and Chemistry, 214, 111277.
https://doi.org/10.1016/j.radphyschem.2023.111277
Katnić ĐB, Porobić S, Vujčić I, Kojić M, Lazarević-Pašti T, Milanković V, Marinović-Cincović M, Živojinović DZ. Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal. in Radiation Physics and Chemistry. 2024;214:111277.
doi:10.1016/j.radphyschem.2023.111277 .
Katnić, Đurica B., Porobić, Slavica, Vujčić, Ivica, Kojić, Marija, Lazarević-Pašti, Tamara, Milanković, Vedran, Marinović-Cincović, Milena, Živojinović, Dragana Z., "Irradiated fig pomace pyrochar as a promising and sustainable sterilized sorbent for water pollutant removal" in Radiation Physics and Chemistry, 214 (2024):111277,
https://doi.org/10.1016/j.radphyschem.2023.111277 . .
1

Dental material based on poly(methyl methacrylate) with magnesium-aluminum layered double hydroxide (MgAl-LDH) on bio-silica particles

Alazreg, Asma; Vuksanović, Marija M.; Mladenović, Ivana O.; Egelja, Adela; Janković-Mandić, Ljiljana; Marinković, Aleksandar; Jančić-Heinemann, Radmila

(2024)

TY  - JOUR
AU  - Alazreg, Asma
AU  - Vuksanović, Marija M.
AU  - Mladenović, Ivana O.
AU  - Egelja, Adela
AU  - Janković-Mandić, Ljiljana
AU  - Marinković, Aleksandar
AU  - Jančić-Heinemann, Radmila
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11720
AB  - The MgAl-LDH@SiO2 particles are prepared by the coprecipitation of LDH on silica originating from plants.Particles are of submicron size and are well dispersed in the matrix. Composites consisting of PMMA reinforcedwith MgAl-LDH@SiO2 particles have improved hardness and resistance to viscoelastic deformation, as tested bymicrohardness measurements.
T2  - Materials Letters
T1  - Dental material based on poly(methyl methacrylate) with magnesium-aluminum layered double hydroxide (MgAl-LDH) on bio-silica particles
VL  - 354
SP  - 135354
DO  - 10.1016/j.matlet.2023.135354
ER  - 
@article{
author = "Alazreg, Asma and Vuksanović, Marija M. and Mladenović, Ivana O. and Egelja, Adela and Janković-Mandić, Ljiljana and Marinković, Aleksandar and Jančić-Heinemann, Radmila",
year = "2024",
abstract = "The MgAl-LDH@SiO2 particles are prepared by the coprecipitation of LDH on silica originating from plants.Particles are of submicron size and are well dispersed in the matrix. Composites consisting of PMMA reinforcedwith MgAl-LDH@SiO2 particles have improved hardness and resistance to viscoelastic deformation, as tested bymicrohardness measurements.",
journal = "Materials Letters",
title = "Dental material based on poly(methyl methacrylate) with magnesium-aluminum layered double hydroxide (MgAl-LDH) on bio-silica particles",
volume = "354",
pages = "135354",
doi = "10.1016/j.matlet.2023.135354"
}
Alazreg, A., Vuksanović, M. M., Mladenović, I. O., Egelja, A., Janković-Mandić, L., Marinković, A.,& Jančić-Heinemann, R.. (2024). Dental material based on poly(methyl methacrylate) with magnesium-aluminum layered double hydroxide (MgAl-LDH) on bio-silica particles. in Materials Letters, 354, 135354.
https://doi.org/10.1016/j.matlet.2023.135354
Alazreg A, Vuksanović MM, Mladenović IO, Egelja A, Janković-Mandić L, Marinković A, Jančić-Heinemann R. Dental material based on poly(methyl methacrylate) with magnesium-aluminum layered double hydroxide (MgAl-LDH) on bio-silica particles. in Materials Letters. 2024;354:135354.
doi:10.1016/j.matlet.2023.135354 .
Alazreg, Asma, Vuksanović, Marija M., Mladenović, Ivana O., Egelja, Adela, Janković-Mandić, Ljiljana, Marinković, Aleksandar, Jančić-Heinemann, Radmila, "Dental material based on poly(methyl methacrylate) with magnesium-aluminum layered double hydroxide (MgAl-LDH) on bio-silica particles" in Materials Letters, 354 (2024):135354,
https://doi.org/10.1016/j.matlet.2023.135354 . .

Antioksidativni i antiinflamatorni efekti suplementacije orasima (Juglans regia L.) na srce pacova sa metaboličkim sindromom izazvanim ishranom bogatom fruktozom

Bubić, Maja

(Универзитет у Београду, Биолошки факултет, 2023-02-01)

TY  - THES
AU  - Bubić, Maja
PY  - 2023-02-01
UR  - https://eteze.bg.ac.rs/application/showtheses?thesesId=9135
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:29732/bdef:Content/download
UR  - https://plus.cobiss.net/cobiss/sr/sr/bib/113470217
UR  - https://nardus.mpn.gov.rs/handle/123456789/21456
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11989
AB  - Povećana konzumacija fruktoze kroz industrijsku hranu doprinosi razvojumetaboličkog sindroma (MetS). MetS prati hronična inflamacija niskog intenziteta kojojdoprinosi oksidativni stres i aktivacija renin-angiotenzin sistema (RAS). Orasi su bogatizvor antioksidanasa i polinezasićenih n-3 masnih kiselina koje imajuantiinflamatorne/imunomodulatorne efekte na kardiometaboličko zdravlje, čijamolekularna osnova nije dovoljno poznata.Konzumacija oraha (2,4 g/dan, 6 nedelja) je smanjila sistolni krvni pritisak kodpacova na ishrani bogatoj fruktozom (10% rastvor, 15 nedelja), pokazala je protektivniefekat na antioksidativnu osu SIRT1-FoxO3a-MnSOD/katalaza i antiinflamatornikapacitet srca (smanjenje AA/EPA) i promovisala antiinflamatorni profil masnih kiselinau plazmi (smanjenje AA/EPA i AA/DHA), koji su kompromitovani fruktoznomishranom. Ulogu negativnih regulatora antioksidativne ose, Nox4 i ChREBP, u srcu trebadodatno ispitati jer je nivo Nox4 povećan i nakon fruktozne ishrane i nakonsuplementacije orasima, dok je nivo ChREBP u jedru smanjen nakon fruktozne ishrane inakon konzumacije oraha kod kontrolnih pacova. Fruktozna ishrana je aktivirala signalniput koji reguliše inflamaciju povećanjem nivoa transkripcionog faktora NF-κB i ključnogenzima RAS-a, АСЕ, dok je suplementacija orasima kod pacova na fruktoznoj ishranipovećala nivo ACE2, kardioprotektivne komponente RAS-a. Na proteinski/iRNK nivoRAS receptora, AT1R i AT2R, nije uticao nijedan od dva nutritivna faktora.Ova studija je potvrdila korisne efekte konzumacije oraha na kardiometaboličkistatus i predloţila mehanizme koji su u osnovi njihovih antiinflamatornih iantioksidativnih efekata u srcu, ukazujući na mogućnost razvoja novih, nefarmakološkihpristupa u terapiji kardiometaboličkih bolesti.
AB  - Increased fructose intake via industrial food is associated with metabolic syndrome(MetS). MetS is characterized by chronic low-intensity inflammation caused by oxidativestress and activation of the renin-angiotensin system (RAS). Walnuts are a rich source ofantioxidants and polyunsaturated n-3 fatty acids that exert anti-inflammatory/immunomodulatory effects on cardiometabolic health, which molecularbackground is underexplored.Walnut consumption (2.4 g/day, 6 weeks) reduced systolic blood pressure in ratsfed a fructose-rich diet (10% FRD, 15 weeks), showed a protective effect on theantioxidative axis SIRT1-FoxO3a-MnSOD/catalase and anti-inflammatory cardiac capacity(AA/EPA reduction) and promoted the anti-inflammatory profile of plasma fatty acids(AA/EPA and AA/DHA reduction), which were compromised by FRD. The role of theaxis negative regulators, Nox4 and ChREBP, should be further investigated in the heartbecause the Nox4 level was increased by both, FRD and walnut supplementation, whilethe ChREBP nuclear level was reduced in FRD as well as in control rats subjected towalnuts. FRD activated a signaling pathway that regulated inflammation by increasing thelevels of the transcription factor NF-κB and the key RAS enzyme, ACE, while walnutsupplementation in FRD rats increased ACE2 level, a cardioprotective component of theRAS. The protein/mRNA levels of the RAS receptors, AT1R and AT2R, were not affectedby either of the two nutritional factors.This study confirmed the beneficial effects of walnut consumption oncardiometabolic status and proposed the mechanisms underlying their anti-inflammatoryand antioxidative effects in the heart, indicating the possibility for development of novel,non-pharmacological approaches in cardiometabolic disease therapy.
PB  - Универзитет у Београду, Биолошки факултет
T2  - Универзитет у Београду
T1  - Antioksidativni i antiinflamatorni efekti suplementacije orasima (Juglans regia L.) na srce pacova sa metaboličkim sindromom izazvanim ishranom bogatom fruktozom
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11989
ER  - 
@phdthesis{
author = "Bubić, Maja",
year = "2023-02-01",
abstract = "Povećana konzumacija fruktoze kroz industrijsku hranu doprinosi razvojumetaboličkog sindroma (MetS). MetS prati hronična inflamacija niskog intenziteta kojojdoprinosi oksidativni stres i aktivacija renin-angiotenzin sistema (RAS). Orasi su bogatizvor antioksidanasa i polinezasićenih n-3 masnih kiselina koje imajuantiinflamatorne/imunomodulatorne efekte na kardiometaboličko zdravlje, čijamolekularna osnova nije dovoljno poznata.Konzumacija oraha (2,4 g/dan, 6 nedelja) je smanjila sistolni krvni pritisak kodpacova na ishrani bogatoj fruktozom (10% rastvor, 15 nedelja), pokazala je protektivniefekat na antioksidativnu osu SIRT1-FoxO3a-MnSOD/katalaza i antiinflamatornikapacitet srca (smanjenje AA/EPA) i promovisala antiinflamatorni profil masnih kiselinau plazmi (smanjenje AA/EPA i AA/DHA), koji su kompromitovani fruktoznomishranom. Ulogu negativnih regulatora antioksidativne ose, Nox4 i ChREBP, u srcu trebadodatno ispitati jer je nivo Nox4 povećan i nakon fruktozne ishrane i nakonsuplementacije orasima, dok je nivo ChREBP u jedru smanjen nakon fruktozne ishrane inakon konzumacije oraha kod kontrolnih pacova. Fruktozna ishrana je aktivirala signalniput koji reguliše inflamaciju povećanjem nivoa transkripcionog faktora NF-κB i ključnogenzima RAS-a, АСЕ, dok je suplementacija orasima kod pacova na fruktoznoj ishranipovećala nivo ACE2, kardioprotektivne komponente RAS-a. Na proteinski/iRNK nivoRAS receptora, AT1R i AT2R, nije uticao nijedan od dva nutritivna faktora.Ova studija je potvrdila korisne efekte konzumacije oraha na kardiometaboličkistatus i predloţila mehanizme koji su u osnovi njihovih antiinflamatornih iantioksidativnih efekata u srcu, ukazujući na mogućnost razvoja novih, nefarmakološkihpristupa u terapiji kardiometaboličkih bolesti., Increased fructose intake via industrial food is associated with metabolic syndrome(MetS). MetS is characterized by chronic low-intensity inflammation caused by oxidativestress and activation of the renin-angiotensin system (RAS). Walnuts are a rich source ofantioxidants and polyunsaturated n-3 fatty acids that exert anti-inflammatory/immunomodulatory effects on cardiometabolic health, which molecularbackground is underexplored.Walnut consumption (2.4 g/day, 6 weeks) reduced systolic blood pressure in ratsfed a fructose-rich diet (10% FRD, 15 weeks), showed a protective effect on theantioxidative axis SIRT1-FoxO3a-MnSOD/catalase and anti-inflammatory cardiac capacity(AA/EPA reduction) and promoted the anti-inflammatory profile of plasma fatty acids(AA/EPA and AA/DHA reduction), which were compromised by FRD. The role of theaxis negative regulators, Nox4 and ChREBP, should be further investigated in the heartbecause the Nox4 level was increased by both, FRD and walnut supplementation, whilethe ChREBP nuclear level was reduced in FRD as well as in control rats subjected towalnuts. FRD activated a signaling pathway that regulated inflammation by increasing thelevels of the transcription factor NF-κB and the key RAS enzyme, ACE, while walnutsupplementation in FRD rats increased ACE2 level, a cardioprotective component of theRAS. The protein/mRNA levels of the RAS receptors, AT1R and AT2R, were not affectedby either of the two nutritional factors.This study confirmed the beneficial effects of walnut consumption oncardiometabolic status and proposed the mechanisms underlying their anti-inflammatoryand antioxidative effects in the heart, indicating the possibility for development of novel,non-pharmacological approaches in cardiometabolic disease therapy.",
publisher = "Универзитет у Београду, Биолошки факултет",
journal = "Универзитет у Београду",
title = "Antioksidativni i antiinflamatorni efekti suplementacije orasima (Juglans regia L.) na srce pacova sa metaboličkim sindromom izazvanim ishranom bogatom fruktozom",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11989"
}
Bubić, M.. (2023-02-01). Antioksidativni i antiinflamatorni efekti suplementacije orasima (Juglans regia L.) na srce pacova sa metaboličkim sindromom izazvanim ishranom bogatom fruktozom. in Универзитет у Београду
Универзитет у Београду, Биолошки факултет..
https://hdl.handle.net/21.15107/rcub_vinar_11989
Bubić M. Antioksidativni i antiinflamatorni efekti suplementacije orasima (Juglans regia L.) na srce pacova sa metaboličkim sindromom izazvanim ishranom bogatom fruktozom. in Универзитет у Београду. 2023;.
https://hdl.handle.net/21.15107/rcub_vinar_11989 .
Bubić, Maja, "Antioksidativni i antiinflamatorni efekti suplementacije orasima (Juglans regia L.) na srce pacova sa metaboličkim sindromom izazvanim ishranom bogatom fruktozom" in Универзитет у Београду (2023-02-01),
https://hdl.handle.net/21.15107/rcub_vinar_11989 .

Sinteza lutecijuma(III) kompleksa sa poliazamakrocikličnim ligandom

Stanić, Vojislav; Tanasković, Slađana; Jelić, Ivana; Janković, Marija; Jovanović, Dragoljub; Gerić, Tamara; Nastasijević, Branislav

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Stanić, Vojislav
AU  - Tanasković, Slađana
AU  - Jelić, Ivana
AU  - Janković, Marija
AU  - Jovanović, Dragoljub
AU  - Gerić, Tamara
AU  - Nastasijević, Branislav
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12188
AB  - Radijacionо zračenje predstavlja specifičan način onkološkog lečenja, kod kojeg se antitumorski efekat postiže dejstvom jonizujućeg zračenja.Visokoenergetsko jonizujuće zračenje oštećuje genetski materijal ćelija tumorskog tkiva i tako ograničava ili onemogućuje njihovu sposobnost daljnjeg deljenja. Radioizotopi koji se koriste u lečenju u većini slučajeva grenerišu beta zračenje koje izaziva uništenje obolelih ćelija. Interesovanje za razvoj 177Lu kao radiofarmaceutika može se pripisati podobnosti njegovih nuklearnih svojstava za terapeutsku upotrebu, emisija β(-) i γ zračenja i njegovo dobro kompleksiranje sa raznim ligandima. U ovom radu je prikazana preliminarna sinteza kompleksa Lu(III) sa poliazamakrocikličnim ligandom.
AB  - Radiation is a specific method of oncological treatment, in which the action of ionizing radiation achieves the antitumor effect. High-energy ionizing radiation damages the genetic material of tumor tissue cells and thus limits or disables their ability to divide further. Radioisotopes used in treatment in most cases generate beta radiation that causes the destruction of diseased cells. The interest in developing 177Lu as a radiopharmaceutical can be attributed to the suitability of its nuclear properties for therapeutic use, the emission ofβ(-) and γ radiation, and its good complexation with various ligands. This paper presents the preliminary synthesis of Lu(III) complex with a polyazamacrocyclic ligand.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Sinteza lutecijuma(III) kompleksa sa poliazamakrocikličnim ligandom
T1  - Synthesis of Lutetium(III) Complex With a Polyazamacrocyclic Ligand
SP  - 395
EP  - 400
ER  - 
@conference{
author = "Stanić, Vojislav and Tanasković, Slađana and Jelić, Ivana and Janković, Marija and Jovanović, Dragoljub and Gerić, Tamara and Nastasijević, Branislav",
year = "2023",
abstract = "Radijacionо zračenje predstavlja specifičan način onkološkog lečenja, kod kojeg se antitumorski efekat postiže dejstvom jonizujućeg zračenja.Visokoenergetsko jonizujuće zračenje oštećuje genetski materijal ćelija tumorskog tkiva i tako ograničava ili onemogućuje njihovu sposobnost daljnjeg deljenja. Radioizotopi koji se koriste u lečenju u većini slučajeva grenerišu beta zračenje koje izaziva uništenje obolelih ćelija. Interesovanje za razvoj 177Lu kao radiofarmaceutika može se pripisati podobnosti njegovih nuklearnih svojstava za terapeutsku upotrebu, emisija β(-) i γ zračenja i njegovo dobro kompleksiranje sa raznim ligandima. U ovom radu je prikazana preliminarna sinteza kompleksa Lu(III) sa poliazamakrocikličnim ligandom., Radiation is a specific method of oncological treatment, in which the action of ionizing radiation achieves the antitumor effect. High-energy ionizing radiation damages the genetic material of tumor tissue cells and thus limits or disables their ability to divide further. Radioisotopes used in treatment in most cases generate beta radiation that causes the destruction of diseased cells. The interest in developing 177Lu as a radiopharmaceutical can be attributed to the suitability of its nuclear properties for therapeutic use, the emission ofβ(-) and γ radiation, and its good complexation with various ligands. This paper presents the preliminary synthesis of Lu(III) complex with a polyazamacrocyclic ligand.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Sinteza lutecijuma(III) kompleksa sa poliazamakrocikličnim ligandom, Synthesis of Lutetium(III) Complex With a Polyazamacrocyclic Ligand",
pages = "395-400"
}
Stanić, V., Tanasković, S., Jelić, I., Janković, M., Jovanović, D., Gerić, T.,& Nastasijević, B.. (2023). Sinteza lutecijuma(III) kompleksa sa poliazamakrocikličnim ligandom. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 395-400.
Stanić V, Tanasković S, Jelić I, Janković M, Jovanović D, Gerić T, Nastasijević B. Sinteza lutecijuma(III) kompleksa sa poliazamakrocikličnim ligandom. in 32. simpozijum DZZSCG : zbornik radova. 2023;:395-400..
Stanić, Vojislav, Tanasković, Slađana, Jelić, Ivana, Janković, Marija, Jovanović, Dragoljub, Gerić, Tamara, Nastasijević, Branislav, "Sinteza lutecijuma(III) kompleksa sa poliazamakrocikličnim ligandom" in 32. simpozijum DZZSCG : zbornik radova (2023):395-400.

The Effect of Honey on Malondialdehyde Level in Plasma Exposed to a Therapeutic Dose of Radiation

Stanić, Vojislav; Gavrilović, Ljubica; Stojiljković, Vesna; Karakašević, Aleksandar; Pantelić, Marija; Gerić, Tamara; Stanković, Srboljub

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Stanić, Vojislav
AU  - Gavrilović, Ljubica
AU  - Stojiljković, Vesna
AU  - Karakašević, Aleksandar
AU  - Pantelić, Marija
AU  - Gerić, Tamara
AU  - Stanković, Srboljub
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12189
AB  - Malondialdehyde (MDA) is the end product of lipid peroxidation and biomarker of free radicals. The aim of this study is to investigate the effect of honey on concentrations of MDA in plasma exposed to a therapeutic dose of radiation. In this experiment animals were divided into two groups: in CONTROL group the animals were given distilled water orally for 28 days, and HONEY group consisted of animals given 1,5 ml/kg honey orally for 28 days. Blood samples of both groups were collected from a rat's tail. All blood samples were exposed to radiation of 2 Gy. Malondialdehyde concentration in plasma was determined using spectrophotometric method. Honey treatment in the blood plasma exposed to a therapeutic dose of 2 Gy significantly decreased MDA level by 30 % compared with control group. The present results indicated that honey had an effect on the levels of MDA in plasma exposed to radiation.
AB  - Malondialdehid (MDA) je krajnji proizvod peroksidacije lipida i biomarker slobodnih radikala. Cilj ovog istraživanja je bio da se ispita uticaj meda na koncentraciju MDA u krvnoj plazmi izloženoj terapijskoj dozi zračenja. U ovom eksperimentu životinje su podeljene u dve grupe: u kontrolnoj grupi životinje su dobijale destilovanu vodu oralno tokom 28 dana, a drugu grupu činile su životinje koje su tokom 28 dana dobijale oralno 1.5 ml/kg meda. Uzorci krvi obe grupe su sakupljeni iz repa pacova. Svi uzorci krvi bili su izloženi zračenju od 2 Gy. Koncentracija MDA u plazmi određena je spektrofotometrijskom metodom. Tretman medom u krvnoj plazmi izložen terapijskoj dozi od 2 Gy značajno je smanjio nivo MDA (30 %) u poređenju sa kontrolnom grupom.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - The Effect of Honey on Malondialdehyde Level in Plasma Exposed to a Therapeutic Dose of Radiation
T1  - Delovanje meda na nivo malondialdehida u plazmi izloženoj terapijskoj dozi zračenja
SP  - 417
EP  - 423
ER  - 
@conference{
author = "Stanić, Vojislav and Gavrilović, Ljubica and Stojiljković, Vesna and Karakašević, Aleksandar and Pantelić, Marija and Gerić, Tamara and Stanković, Srboljub",
year = "2023",
abstract = "Malondialdehyde (MDA) is the end product of lipid peroxidation and biomarker of free radicals. The aim of this study is to investigate the effect of honey on concentrations of MDA in plasma exposed to a therapeutic dose of radiation. In this experiment animals were divided into two groups: in CONTROL group the animals were given distilled water orally for 28 days, and HONEY group consisted of animals given 1,5 ml/kg honey orally for 28 days. Blood samples of both groups were collected from a rat's tail. All blood samples were exposed to radiation of 2 Gy. Malondialdehyde concentration in plasma was determined using spectrophotometric method. Honey treatment in the blood plasma exposed to a therapeutic dose of 2 Gy significantly decreased MDA level by 30 % compared with control group. The present results indicated that honey had an effect on the levels of MDA in plasma exposed to radiation., Malondialdehid (MDA) je krajnji proizvod peroksidacije lipida i biomarker slobodnih radikala. Cilj ovog istraživanja je bio da se ispita uticaj meda na koncentraciju MDA u krvnoj plazmi izloženoj terapijskoj dozi zračenja. U ovom eksperimentu životinje su podeljene u dve grupe: u kontrolnoj grupi životinje su dobijale destilovanu vodu oralno tokom 28 dana, a drugu grupu činile su životinje koje su tokom 28 dana dobijale oralno 1.5 ml/kg meda. Uzorci krvi obe grupe su sakupljeni iz repa pacova. Svi uzorci krvi bili su izloženi zračenju od 2 Gy. Koncentracija MDA u plazmi određena je spektrofotometrijskom metodom. Tretman medom u krvnoj plazmi izložen terapijskoj dozi od 2 Gy značajno je smanjio nivo MDA (30 %) u poređenju sa kontrolnom grupom.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "The Effect of Honey on Malondialdehyde Level in Plasma Exposed to a Therapeutic Dose of Radiation, Delovanje meda na nivo malondialdehida u plazmi izloženoj terapijskoj dozi zračenja",
pages = "417-423"
}
Stanić, V., Gavrilović, L., Stojiljković, V., Karakašević, A., Pantelić, M., Gerić, T.,& Stanković, S.. (2023). The Effect of Honey on Malondialdehyde Level in Plasma Exposed to a Therapeutic Dose of Radiation. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 417-423.
Stanić V, Gavrilović L, Stojiljković V, Karakašević A, Pantelić M, Gerić T, Stanković S. The Effect of Honey on Malondialdehyde Level in Plasma Exposed to a Therapeutic Dose of Radiation. in 32. simpozijum DZZSCG : zbornik radova. 2023;:417-423..
Stanić, Vojislav, Gavrilović, Ljubica, Stojiljković, Vesna, Karakašević, Aleksandar, Pantelić, Marija, Gerić, Tamara, Stanković, Srboljub, "The Effect of Honey on Malondialdehyde Level in Plasma Exposed to a Therapeutic Dose of Radiation" in 32. simpozijum DZZSCG : zbornik radova (2023):417-423.

Automatizacija procesa proizvodnje radiofarmaceutika u cilju smanjenja doze zračenja operatera

Vukadinović, Aleksandar; Ravlić, Miroslav; Matović, Milovan; Janković, Drina; Mirković, Marija D.; Radović, Magdalena; Milanović, Zorana; Perić, Marko; Stanković, Dragana; Jevremović, Milutin; Vranješ-Đurić, Sanja

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Vukadinović, Aleksandar
AU  - Ravlić, Miroslav
AU  - Matović, Milovan
AU  - Janković, Drina
AU  - Mirković, Marija D.
AU  - Radović, Magdalena
AU  - Milanović, Zorana
AU  - Perić, Marko
AU  - Stanković, Dragana
AU  - Jevremović, Milutin
AU  - Vranješ-Đurić, Sanja
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12187
AB  - Laboratorija za radioizotope Instituta Vinča je jedinstven centar u regionu koji poseduje Rešenja Ministarstva zdravlja Republike Srbije i Direktorata za radijacionu i nuklearnu sigurnost i bezbednost Srbije za proizvodnju radiofarmaceutika. Radiofarmaceutik koji se proizvodi više od 40 godina u Laboratoriji za radioizotope, a primenjuje u terapiji tumora štitaste žlezde, kao i hipertireozi su kapsule natrijum-jodida (I-131). Radijacioni efekti I-131 na ćelije štitaste žlezde potiču od beta-zračenja koje emituje I-131 tokom radioaktivnog raspada u samoj štitastoj žlezdi jer se I-131 nakon oralne primene nakuplja prvenstveno u štitastoj žlezdi u kojoj ima dugu retenciju. Za efikasnu terapiju, ali u isto vreme u cilju smanjenja izloženosti nepotrebnim dozama, za svakog pacijenta određuje se odgovarajuća doza I-131 koju je neophodno da primi, odnosno primenjuje se tzv. personalizovana terapija. U radu je opisan postupak proizvodnje kapsula I-131 u Laboratoriji za radioizotope putem manuelnog punjenja kapsula rastvorom I-131, kao i osnovni zahtevi koje je neophodno da sistem za automatsku proizvodnju radiofarmaceutika ispuni, a to su pre svih, odgovarajuća zaštita operatera od zračenja, jednostavna upotreba i kompjuterska kontrola.
AB  - The Laboratory for radioisotopes of the Vinča Institute is a unique center in the region with licences of the Ministry of Health of the Republic of Serbia and the Directorate for Radiation and Nuclear Safety and Security of Serbia for the production of radiopharmaceuticals. Sodium iodide (I-131) capsules are radiopharmaceuticals that have been produced for more than 40 years in the Laboratory for Radioisotopes, and are used in the treatment of tumors of thyroid gland, as well as in hyperthyroidism. The radiation effects of I-131 on thyroid cells originate from beta-radiation emitted by I-131 during radioactive decay in the thyroid gland itself because I-131 after oral administration accumulates primarily in the thyroid gland where it has a long retention. For the effective therapy, but at the same time in order to reduce exposure to unnecessary high doses, the appropriate dose of I-131 is determined for each patient, in the so-called personalized therapy. The paper describes the current procedure for the production of I-131 capsules in the Laboratory for Radioisotopes by manually filling the capsules with I-131 solution and the basic requirements for design the system for automating the production of radiopharmaceuticals, which above all must provide adequate protection for the operator from radiation, must be user friendly and computer-controlled.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Automatizacija procesa proizvodnje radiofarmaceutika u cilju smanjenja doze zračenja operatera
T1  - Automation of the Production of Radiopharmaceutical with the Aim to Reduce the Operator's Radiation Dose
SP  - 356
EP  - 360
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12187
ER  - 
@conference{
author = "Vukadinović, Aleksandar and Ravlić, Miroslav and Matović, Milovan and Janković, Drina and Mirković, Marija D. and Radović, Magdalena and Milanović, Zorana and Perić, Marko and Stanković, Dragana and Jevremović, Milutin and Vranješ-Đurić, Sanja",
year = "2023",
abstract = "Laboratorija za radioizotope Instituta Vinča je jedinstven centar u regionu koji poseduje Rešenja Ministarstva zdravlja Republike Srbije i Direktorata za radijacionu i nuklearnu sigurnost i bezbednost Srbije za proizvodnju radiofarmaceutika. Radiofarmaceutik koji se proizvodi više od 40 godina u Laboratoriji za radioizotope, a primenjuje u terapiji tumora štitaste žlezde, kao i hipertireozi su kapsule natrijum-jodida (I-131). Radijacioni efekti I-131 na ćelije štitaste žlezde potiču od beta-zračenja koje emituje I-131 tokom radioaktivnog raspada u samoj štitastoj žlezdi jer se I-131 nakon oralne primene nakuplja prvenstveno u štitastoj žlezdi u kojoj ima dugu retenciju. Za efikasnu terapiju, ali u isto vreme u cilju smanjenja izloženosti nepotrebnim dozama, za svakog pacijenta određuje se odgovarajuća doza I-131 koju je neophodno da primi, odnosno primenjuje se tzv. personalizovana terapija. U radu je opisan postupak proizvodnje kapsula I-131 u Laboratoriji za radioizotope putem manuelnog punjenja kapsula rastvorom I-131, kao i osnovni zahtevi koje je neophodno da sistem za automatsku proizvodnju radiofarmaceutika ispuni, a to su pre svih, odgovarajuća zaštita operatera od zračenja, jednostavna upotreba i kompjuterska kontrola., The Laboratory for radioisotopes of the Vinča Institute is a unique center in the region with licences of the Ministry of Health of the Republic of Serbia and the Directorate for Radiation and Nuclear Safety and Security of Serbia for the production of radiopharmaceuticals. Sodium iodide (I-131) capsules are radiopharmaceuticals that have been produced for more than 40 years in the Laboratory for Radioisotopes, and are used in the treatment of tumors of thyroid gland, as well as in hyperthyroidism. The radiation effects of I-131 on thyroid cells originate from beta-radiation emitted by I-131 during radioactive decay in the thyroid gland itself because I-131 after oral administration accumulates primarily in the thyroid gland where it has a long retention. For the effective therapy, but at the same time in order to reduce exposure to unnecessary high doses, the appropriate dose of I-131 is determined for each patient, in the so-called personalized therapy. The paper describes the current procedure for the production of I-131 capsules in the Laboratory for Radioisotopes by manually filling the capsules with I-131 solution and the basic requirements for design the system for automating the production of radiopharmaceuticals, which above all must provide adequate protection for the operator from radiation, must be user friendly and computer-controlled.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Automatizacija procesa proizvodnje radiofarmaceutika u cilju smanjenja doze zračenja operatera, Automation of the Production of Radiopharmaceutical with the Aim to Reduce the Operator's Radiation Dose",
pages = "356-360",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12187"
}
Vukadinović, A., Ravlić, M., Matović, M., Janković, D., Mirković, M. D., Radović, M., Milanović, Z., Perić, M., Stanković, D., Jevremović, M.,& Vranješ-Đurić, S.. (2023). Automatizacija procesa proizvodnje radiofarmaceutika u cilju smanjenja doze zračenja operatera. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 356-360.
https://hdl.handle.net/21.15107/rcub_vinar_12187
Vukadinović A, Ravlić M, Matović M, Janković D, Mirković MD, Radović M, Milanović Z, Perić M, Stanković D, Jevremović M, Vranješ-Đurić S. Automatizacija procesa proizvodnje radiofarmaceutika u cilju smanjenja doze zračenja operatera. in 32. simpozijum DZZSCG : zbornik radova. 2023;:356-360.
https://hdl.handle.net/21.15107/rcub_vinar_12187 .
Vukadinović, Aleksandar, Ravlić, Miroslav, Matović, Milovan, Janković, Drina, Mirković, Marija D., Radović, Magdalena, Milanović, Zorana, Perić, Marko, Stanković, Dragana, Jevremović, Milutin, Vranješ-Đurić, Sanja, "Automatizacija procesa proizvodnje radiofarmaceutika u cilju smanjenja doze zračenja operatera" in 32. simpozijum DZZSCG : zbornik radova (2023):356-360,
https://hdl.handle.net/21.15107/rcub_vinar_12187 .

Validacija ITLC metode za određivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji

Janković, Drina; Mirković, Marija D.; Radović, Magdalena; Milanović, Zorana; Perić, Marko; Stanković, Dragana; Vukadinović, Aleksandar; Vranješ-Đurić, Sanja

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Janković, Drina
AU  - Mirković, Marija D.
AU  - Radović, Magdalena
AU  - Milanović, Zorana
AU  - Perić, Marko
AU  - Stanković, Dragana
AU  - Vukadinović, Aleksandar
AU  - Vranješ-Đurić, Sanja
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12185
AB  - Prisustvo radiohemijske nečistoće C u 99mTc-MIBI injekciji utiče na kvalitet skena, jer se radiofarmaceutik nedovoljno nakuplja u organu od interesa, dok je aktivnost okolnih organa i tkiva velika. Zbog toga je i doza zračenja koju prime okolni organi i tkiva iznad propisanih granica. Da bi se obezbedilo da je planirano izlaganje zračenju pacijenata svedeno na minimum, farmakopeja zahteva ispitivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji neposredno pre primene radiofarmaceutika u pacijenta. Za ova ispitivanja se koriste metode hromatografije. U radu je predstavljena brza i osetljiva ITLC metoda namenjena za rutinsko ispitivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji. ITLC metoda je validirana, a ispitivani su pogodnost sistema, tačnost, preciznost, ponovljivost, specifičnost, limit detekcije, limit kvantifikacije, linearnost, robustnost i osetljivost metode. Dobre "recovery" vrednosti i niska relativna standardna devijacija potvrđuju da je predložena ITLC metoda pogodna za rutinsko određivanje nečistoće C u 99mTc-MIBI u injekciji.
AB  - The European Pharmacopoeia mandates that all radiopharmaceuticals used in nuclear medicine for diagnostic and therapeutic purposes must be of the correct radiochemical and radionuclidic purity and have the correct radioactivity present at the stated time of injection to ensure that the intended radiation exposure of patients is kept to a minimum. These factors have an effect on the overall radiation dose to the patient, as impurities of the radionuclide and/or its chemical composition may affect the biodistribution of the injected radiopharmaceutical and consequently the radiation dose to any one particular organ or the whole body dose. The presence of radiochemical impurity C in 99mTc-MIBI injection affects the quality of the image, because 99mTc-MIBI accumulates insufficiently in the organ of interest, while the activity of the surrounding organs and tissues is high. Therefore, the radiation dose received by the surrounding organs and tissues is above the permitted level. In order to avoid unnecessary irradiation of surrounding organs and tissues, the pharmacopoeia requires examination of the content of radiochemical impurity C immediately before administering of 99mTc-MIBI to the patient. Chromatographic methods are used for these tests. The paper presents a fast and sensitive ITLC method intended for routine examination of the content of radiochemical impurity C in 99mTc-MIBI injection. The ITLC method was validated, and the suitability of the system, accuracy, precision, repeatability, specificity, limit of detection, limit of quantification, linearity, robustness and sensitivity of the method were examined. Good "recovery" values and low relative standard deviation confirm that the proposed ITLC method is suitable for routine determination of impurity C in 99mTc-MIBI in injection.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Validacija ITLC metode za određivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji
T1  - Validation of an ITLC Method for the Determination of Radiochemical Impurities C in 99mTc-MIBI Injection
SP  - 342
EP  - 349
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12185
ER  - 
@conference{
author = "Janković, Drina and Mirković, Marija D. and Radović, Magdalena and Milanović, Zorana and Perić, Marko and Stanković, Dragana and Vukadinović, Aleksandar and Vranješ-Đurić, Sanja",
year = "2023",
abstract = "Prisustvo radiohemijske nečistoće C u 99mTc-MIBI injekciji utiče na kvalitet skena, jer se radiofarmaceutik nedovoljno nakuplja u organu od interesa, dok je aktivnost okolnih organa i tkiva velika. Zbog toga je i doza zračenja koju prime okolni organi i tkiva iznad propisanih granica. Da bi se obezbedilo da je planirano izlaganje zračenju pacijenata svedeno na minimum, farmakopeja zahteva ispitivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji neposredno pre primene radiofarmaceutika u pacijenta. Za ova ispitivanja se koriste metode hromatografije. U radu je predstavljena brza i osetljiva ITLC metoda namenjena za rutinsko ispitivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji. ITLC metoda je validirana, a ispitivani su pogodnost sistema, tačnost, preciznost, ponovljivost, specifičnost, limit detekcije, limit kvantifikacije, linearnost, robustnost i osetljivost metode. Dobre "recovery" vrednosti i niska relativna standardna devijacija potvrđuju da je predložena ITLC metoda pogodna za rutinsko određivanje nečistoće C u 99mTc-MIBI u injekciji., The European Pharmacopoeia mandates that all radiopharmaceuticals used in nuclear medicine for diagnostic and therapeutic purposes must be of the correct radiochemical and radionuclidic purity and have the correct radioactivity present at the stated time of injection to ensure that the intended radiation exposure of patients is kept to a minimum. These factors have an effect on the overall radiation dose to the patient, as impurities of the radionuclide and/or its chemical composition may affect the biodistribution of the injected radiopharmaceutical and consequently the radiation dose to any one particular organ or the whole body dose. The presence of radiochemical impurity C in 99mTc-MIBI injection affects the quality of the image, because 99mTc-MIBI accumulates insufficiently in the organ of interest, while the activity of the surrounding organs and tissues is high. Therefore, the radiation dose received by the surrounding organs and tissues is above the permitted level. In order to avoid unnecessary irradiation of surrounding organs and tissues, the pharmacopoeia requires examination of the content of radiochemical impurity C immediately before administering of 99mTc-MIBI to the patient. Chromatographic methods are used for these tests. The paper presents a fast and sensitive ITLC method intended for routine examination of the content of radiochemical impurity C in 99mTc-MIBI injection. The ITLC method was validated, and the suitability of the system, accuracy, precision, repeatability, specificity, limit of detection, limit of quantification, linearity, robustness and sensitivity of the method were examined. Good "recovery" values and low relative standard deviation confirm that the proposed ITLC method is suitable for routine determination of impurity C in 99mTc-MIBI in injection.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Validacija ITLC metode za određivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji, Validation of an ITLC Method for the Determination of Radiochemical Impurities C in 99mTc-MIBI Injection",
pages = "342-349",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12185"
}
Janković, D., Mirković, M. D., Radović, M., Milanović, Z., Perić, M., Stanković, D., Vukadinović, A.,& Vranješ-Đurić, S.. (2023). Validacija ITLC metode za određivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 342-349.
https://hdl.handle.net/21.15107/rcub_vinar_12185
Janković D, Mirković MD, Radović M, Milanović Z, Perić M, Stanković D, Vukadinović A, Vranješ-Đurić S. Validacija ITLC metode za određivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji. in 32. simpozijum DZZSCG : zbornik radova. 2023;:342-349.
https://hdl.handle.net/21.15107/rcub_vinar_12185 .
Janković, Drina, Mirković, Marija D., Radović, Magdalena, Milanović, Zorana, Perić, Marko, Stanković, Dragana, Vukadinović, Aleksandar, Vranješ-Đurić, Sanja, "Validacija ITLC metode za određivanje sadržaja radiohemijske nečistoće C u 99mTc-MIBI injekciji" in 32. simpozijum DZZSCG : zbornik radova (2023):342-349,
https://hdl.handle.net/21.15107/rcub_vinar_12185 .

Metoda ispitivanja fiziološke raspodele 99mTc-DPD

Milanović, Zorana; Mirković, Marija D.; Radović, Magdalena; Perić, Marko; Stanković, Dragana; Vukadinović, Aleksandar; Vranješ-Đurić, Sanja; Janković, Drina

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Milanović, Zorana
AU  - Mirković, Marija D.
AU  - Radović, Magdalena
AU  - Perić, Marko
AU  - Stanković, Dragana
AU  - Vukadinović, Aleksandar
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12186
AB  - Radiofarmaceutici koji se koriste za ispitivanje skeletnog sistema od neprocenjivog su značaja u nuklearnoj medicini, kako za dijagnostiku primarnih tumora koštanog tkiva, tako i metastaza. Pre primene na pacijentima, ovi radiofarmaceutici podležu različitim fizičko-hemijskim i biološkim ispitivanjima. Ispitivanje fiziološke raspodele leka in vivo je od presudnog značaja jer od akumulacije leka u odgovarajućoj meri u ciljnom organu (skeletu) zavisi kvalitet dobijenog scintigrama, kao i doza zračenja koje će primiti pojedinačni organi i tkiva. U evropskoj farmakopeji (Ph.Eur.) date su metode kontrole kvaliteta kao i parametri kvaliteta sa granicama prihvatljivosti (specifikacijske granice) za 99mTc-metilendifosfonat (99mTc-MDP). Cilj ovog rada je prikaz metode ispitivanja fiziološke raspodele 99mTc-DPD koja je razvijena u Laboratoriji za radioizotope po smernicama evropske farmakopeje za 99mTc-MDP, uz manje modifikacije. Rezultati biodistribucije na Wistar pacovima su pokazali da je 99mTc-DPD proizveden u Laboratoriji za radioizotope zadovoljio sve postavljene kriterijume, kako odmah nakon proizvodnje, tako i nakon šest i dvanaest meseci od proizvodnje.
AB  - Radiopharmaceuticals used to examine the skeletal system are of invaluable importance in nuclear medicine, both for the diagnosis of primary bone tissue tumors and metastases. Before administration to patients, these radiopharmaceuticals undergo various physico-chemical and biological tests. Investigation of the physiological distribution of the drug in vivo is of crucial importance because the quality of the obtained scintigram depends on the accumulation of the drug in the target organ (skeleton), as well as the radiation dose received by individual organs and tissues. The European pharmacopoeia (Ph.Eur.) provides quality control methods and quality parameters with acceptance limits (specification limits) for 99mTc-methylenediphosphonate (99mTc-MDP). The method of testing the physiological distribution of 99mTc-DPD in the Laboratory for Radioisotopes, which is presented in this paper, is done according to the guidelines of the European Pharmacopoeia for 99mTc-MDP, with minor modifications. Results of biodistribution on Wistar rats showed that 99mTc-DPD produced in the Laboratory for Radioisotopes met all the set criteria, both immediately after the production and after six and twelve months from production.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Metoda ispitivanja fiziološke raspodele 99mTc-DPD
T1  - Method for Investigation of Physiological Distribution of 99mTc DPD
SP  - 350
EP  - 355
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12186
ER  - 
@conference{
author = "Milanović, Zorana and Mirković, Marija D. and Radović, Magdalena and Perić, Marko and Stanković, Dragana and Vukadinović, Aleksandar and Vranješ-Đurić, Sanja and Janković, Drina",
year = "2023",
abstract = "Radiofarmaceutici koji se koriste za ispitivanje skeletnog sistema od neprocenjivog su značaja u nuklearnoj medicini, kako za dijagnostiku primarnih tumora koštanog tkiva, tako i metastaza. Pre primene na pacijentima, ovi radiofarmaceutici podležu različitim fizičko-hemijskim i biološkim ispitivanjima. Ispitivanje fiziološke raspodele leka in vivo je od presudnog značaja jer od akumulacije leka u odgovarajućoj meri u ciljnom organu (skeletu) zavisi kvalitet dobijenog scintigrama, kao i doza zračenja koje će primiti pojedinačni organi i tkiva. U evropskoj farmakopeji (Ph.Eur.) date su metode kontrole kvaliteta kao i parametri kvaliteta sa granicama prihvatljivosti (specifikacijske granice) za 99mTc-metilendifosfonat (99mTc-MDP). Cilj ovog rada je prikaz metode ispitivanja fiziološke raspodele 99mTc-DPD koja je razvijena u Laboratoriji za radioizotope po smernicama evropske farmakopeje za 99mTc-MDP, uz manje modifikacije. Rezultati biodistribucije na Wistar pacovima su pokazali da je 99mTc-DPD proizveden u Laboratoriji za radioizotope zadovoljio sve postavljene kriterijume, kako odmah nakon proizvodnje, tako i nakon šest i dvanaest meseci od proizvodnje., Radiopharmaceuticals used to examine the skeletal system are of invaluable importance in nuclear medicine, both for the diagnosis of primary bone tissue tumors and metastases. Before administration to patients, these radiopharmaceuticals undergo various physico-chemical and biological tests. Investigation of the physiological distribution of the drug in vivo is of crucial importance because the quality of the obtained scintigram depends on the accumulation of the drug in the target organ (skeleton), as well as the radiation dose received by individual organs and tissues. The European pharmacopoeia (Ph.Eur.) provides quality control methods and quality parameters with acceptance limits (specification limits) for 99mTc-methylenediphosphonate (99mTc-MDP). The method of testing the physiological distribution of 99mTc-DPD in the Laboratory for Radioisotopes, which is presented in this paper, is done according to the guidelines of the European Pharmacopoeia for 99mTc-MDP, with minor modifications. Results of biodistribution on Wistar rats showed that 99mTc-DPD produced in the Laboratory for Radioisotopes met all the set criteria, both immediately after the production and after six and twelve months from production.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Metoda ispitivanja fiziološke raspodele 99mTc-DPD, Method for Investigation of Physiological Distribution of 99mTc DPD",
pages = "350-355",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12186"
}
Milanović, Z., Mirković, M. D., Radović, M., Perić, M., Stanković, D., Vukadinović, A., Vranješ-Đurić, S.,& Janković, D.. (2023). Metoda ispitivanja fiziološke raspodele 99mTc-DPD. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 350-355.
https://hdl.handle.net/21.15107/rcub_vinar_12186
Milanović Z, Mirković MD, Radović M, Perić M, Stanković D, Vukadinović A, Vranješ-Đurić S, Janković D. Metoda ispitivanja fiziološke raspodele 99mTc-DPD. in 32. simpozijum DZZSCG : zbornik radova. 2023;:350-355.
https://hdl.handle.net/21.15107/rcub_vinar_12186 .
Milanović, Zorana, Mirković, Marija D., Radović, Magdalena, Perić, Marko, Stanković, Dragana, Vukadinović, Aleksandar, Vranješ-Đurić, Sanja, Janković, Drina, "Metoda ispitivanja fiziološke raspodele 99mTc-DPD" in 32. simpozijum DZZSCG : zbornik radova (2023):350-355,
https://hdl.handle.net/21.15107/rcub_vinar_12186 .

Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta

Rajković, Katarina M.; Đurašević, Mirjana; Obradović, Zorica; Milanović, Zorana; Vukadinović, Aleksandar; Perić, Marko; Stanković, Dragana; Janković, Drina

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Rajković, Katarina M.
AU  - Đurašević, Mirjana
AU  - Obradović, Zorica
AU  - Milanović, Zorana
AU  - Vukadinović, Aleksandar
AU  - Perić, Marko
AU  - Stanković, Dragana
AU  - Janković, Drina
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12184
AB  - Tc-99m-radiofarmaceutici se koriste u različitim dijagnostičkim procedurama u nuklearnoj medicini. Da bi se minimizirali štetni efekti jonizujućeg zračenja na zdrava tkiva, intenzivno se istražuju radioprotektivne osobine biljnih ekstrakata. Ljuska ploda crnog oraha sadrži mešavinu različitih farmakološki aktivnih jedinjenja kojа imaju antioksidativno dejstvo i za koje se pretpostavlja da mogu imati i potencijalno radioprotektivno dejstvo. U tom kontekstu, cilj rada je bio da se proceni radioprotektivni efekat ekstrakta ljuske ploda crnog oraha. U ovoj studiji primenjen je eksperimentalni model koji se zasnivao na proceni uticaja ekstrakta na biodistribuciju Tc-99m-radiofarmaceutika po organima eksperimentalnih životinja (pacovi). Ekstrakt ljuske crnog oraha doveo je do smanjenognakupljanja Tc-99m-radiofarmaceutika u pojedinim organimapacova. Rezultati dobijeni na osnovu eksperimentalnog modela sugerišu moguću upotrebu ekstrakta ljuske ploda crnog oraha kao radioprotektivnog sredstva u slučajevima planiranog izlaganja jonizujućem zračenju u nuklearnoj medicini.
AB  - Tc-99m-radiopharmaceuticals are used in various diagnostic procedures in nuclear medicine. In order to minimize the harmful effects of ionizing radiation on healthy tissues, the radioprotective properties of plant extracts are intensively researched. J. nigra husk contains a mixture of various pharmacologically active compounds that have an antioxidant effect and which are assumed to have a potential radioprotective effect. In this context, the aim of the work was to evaluate the radioprotective effect of black walnut husk extract. In this study, an experimental model was applied, which was based on the assessment of the effect of the extract on the biodistribution of Tc-99m-radiopharmaceuticals in the organs of experimental animals (rats). Black walnut husk extract led to a decrease in the accumulation of Tc-99m-radiopharmaceutical in certain organs of rats. The results obtained on the basis of the experimental model suggest that it is possible to use black walnut husk extract as a radioprotective agent in cases of planned exposure to ionizing radiation in diagnosticsnuclear medicine.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta
T1  - Experimental Model for Assessing the Possible Radioprotective Effect of Plant Extract
SP  - 321
EP  - 327
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12184
ER  - 
@conference{
author = "Rajković, Katarina M. and Đurašević, Mirjana and Obradović, Zorica and Milanović, Zorana and Vukadinović, Aleksandar and Perić, Marko and Stanković, Dragana and Janković, Drina",
year = "2023",
abstract = "Tc-99m-radiofarmaceutici se koriste u različitim dijagnostičkim procedurama u nuklearnoj medicini. Da bi se minimizirali štetni efekti jonizujućeg zračenja na zdrava tkiva, intenzivno se istražuju radioprotektivne osobine biljnih ekstrakata. Ljuska ploda crnog oraha sadrži mešavinu različitih farmakološki aktivnih jedinjenja kojа imaju antioksidativno dejstvo i za koje se pretpostavlja da mogu imati i potencijalno radioprotektivno dejstvo. U tom kontekstu, cilj rada je bio da se proceni radioprotektivni efekat ekstrakta ljuske ploda crnog oraha. U ovoj studiji primenjen je eksperimentalni model koji se zasnivao na proceni uticaja ekstrakta na biodistribuciju Tc-99m-radiofarmaceutika po organima eksperimentalnih životinja (pacovi). Ekstrakt ljuske crnog oraha doveo je do smanjenognakupljanja Tc-99m-radiofarmaceutika u pojedinim organimapacova. Rezultati dobijeni na osnovu eksperimentalnog modela sugerišu moguću upotrebu ekstrakta ljuske ploda crnog oraha kao radioprotektivnog sredstva u slučajevima planiranog izlaganja jonizujućem zračenju u nuklearnoj medicini., Tc-99m-radiopharmaceuticals are used in various diagnostic procedures in nuclear medicine. In order to minimize the harmful effects of ionizing radiation on healthy tissues, the radioprotective properties of plant extracts are intensively researched. J. nigra husk contains a mixture of various pharmacologically active compounds that have an antioxidant effect and which are assumed to have a potential radioprotective effect. In this context, the aim of the work was to evaluate the radioprotective effect of black walnut husk extract. In this study, an experimental model was applied, which was based on the assessment of the effect of the extract on the biodistribution of Tc-99m-radiopharmaceuticals in the organs of experimental animals (rats). Black walnut husk extract led to a decrease in the accumulation of Tc-99m-radiopharmaceutical in certain organs of rats. The results obtained on the basis of the experimental model suggest that it is possible to use black walnut husk extract as a radioprotective agent in cases of planned exposure to ionizing radiation in diagnosticsnuclear medicine.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta, Experimental Model for Assessing the Possible Radioprotective Effect of Plant Extract",
pages = "321-327",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12184"
}
Rajković, K. M., Đurašević, M., Obradović, Z., Milanović, Z., Vukadinović, A., Perić, M., Stanković, D.,& Janković, D.. (2023). Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 321-327.
https://hdl.handle.net/21.15107/rcub_vinar_12184
Rajković KM, Đurašević M, Obradović Z, Milanović Z, Vukadinović A, Perić M, Stanković D, Janković D. Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta. in 32. simpozijum DZZSCG : zbornik radova. 2023;:321-327.
https://hdl.handle.net/21.15107/rcub_vinar_12184 .
Rajković, Katarina M., Đurašević, Mirjana, Obradović, Zorica, Milanović, Zorana, Vukadinović, Aleksandar, Perić, Marko, Stanković, Dragana, Janković, Drina, "Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta" in 32. simpozijum DZZSCG : zbornik radova (2023):321-327,
https://hdl.handle.net/21.15107/rcub_vinar_12184 .

Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora

Stanković, Jovan; Mirkov, Zoran; Dabić-Stanković, Kata; Obradović, Zorica; Rajković, Katarina

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Stanković, Jovan
AU  - Mirkov, Zoran
AU  - Dabić-Stanković, Kata
AU  - Obradović, Zorica
AU  - Rajković, Katarina
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12183
AB  - Brahiterapijski uređaji sa izvorima velike aktivnosti (> 370 GBq) postavljaju se u posebne zaštitne bunkere, debljine zaštitnog betonskog zida oko 70 cm, što zahteva opsežnije građevinsko-tehničke radove i povećava cenu izrade (preko 100.000 Eura). Da bi se prevazišao problem ograničenog prostora unutar odeljenja brahiterapije, predlažemo izradu „brahiterapijske komore“ koja bi bila smeštena u aplikacionoj sali minimalne površine 30 m2. Komandni pult brahiterapijskog uređaja bi se nalazilo u parapetom/paravanom odvojenom delu sale. Brahiterapijska komora, pojedinačnih dimenzija (V x Š) oko 2 m, u obliku ćiričnog slova P (П), izrađuje se od olovnih ploča debljine 5 cm. Sa jedne strane komore (ulaz za pacijenta) navlačiće se pokretni/motorizovani paravan (debljine zida: 5 cm; dimenzija V x Š oko 2,3 m). U toku zračenja pacijent i uređaj se nalaze u komori. Cena izrade ove brahiterapijske komore sa pripadajućim elementima ne bi prelazila cenu izrade klasičnog brahiterapijskog bunkera.
AB  - Brachytherapy units with high activity sources (> 370 GBq) are placed in special protective treatment rooms, with concrete wall thickness of about 70 cm, which requires more extensive construction and technical works that increases the cost of production (over 100.000 Euros). In order to overcome the problem of limited space within the brachytherapy department, we propose construction of a "brachytherapy chamber" that would be located in the application teatre with a minimum area of 30 sqm. The control unit would be located in a separated part of the treatment room. The brachytherapy chamber, with an individual dimensions (H x W) of about 2 m, in the shape of the Cyrillic letter P (П), is made of lead plates 5 cm thick. On one side of the chamber (patient entrance) a movable/motorized screen (wall thickness: 5 cm; dimensions HxW each approx. 2.3 m) will be constructed. During radiation, the patient and theunit are in the chamber. The construction cost of this brachytherapy chamber with associated elements would not exceed the cost of making a classic brachytherapy treatment room.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora
T1  - A New Approach in the Construction of Protection in Brachytherapy – Brachytherapy Chamber
SP  - 313
EP  - 320
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12183
ER  - 
@conference{
author = "Stanković, Jovan and Mirkov, Zoran and Dabić-Stanković, Kata and Obradović, Zorica and Rajković, Katarina",
year = "2023",
abstract = "Brahiterapijski uređaji sa izvorima velike aktivnosti (> 370 GBq) postavljaju se u posebne zaštitne bunkere, debljine zaštitnog betonskog zida oko 70 cm, što zahteva opsežnije građevinsko-tehničke radove i povećava cenu izrade (preko 100.000 Eura). Da bi se prevazišao problem ograničenog prostora unutar odeljenja brahiterapije, predlažemo izradu „brahiterapijske komore“ koja bi bila smeštena u aplikacionoj sali minimalne površine 30 m2. Komandni pult brahiterapijskog uređaja bi se nalazilo u parapetom/paravanom odvojenom delu sale. Brahiterapijska komora, pojedinačnih dimenzija (V x Š) oko 2 m, u obliku ćiričnog slova P (П), izrađuje se od olovnih ploča debljine 5 cm. Sa jedne strane komore (ulaz za pacijenta) navlačiće se pokretni/motorizovani paravan (debljine zida: 5 cm; dimenzija V x Š oko 2,3 m). U toku zračenja pacijent i uređaj se nalaze u komori. Cena izrade ove brahiterapijske komore sa pripadajućim elementima ne bi prelazila cenu izrade klasičnog brahiterapijskog bunkera., Brachytherapy units with high activity sources (> 370 GBq) are placed in special protective treatment rooms, with concrete wall thickness of about 70 cm, which requires more extensive construction and technical works that increases the cost of production (over 100.000 Euros). In order to overcome the problem of limited space within the brachytherapy department, we propose construction of a "brachytherapy chamber" that would be located in the application teatre with a minimum area of 30 sqm. The control unit would be located in a separated part of the treatment room. The brachytherapy chamber, with an individual dimensions (H x W) of about 2 m, in the shape of the Cyrillic letter P (П), is made of lead plates 5 cm thick. On one side of the chamber (patient entrance) a movable/motorized screen (wall thickness: 5 cm; dimensions HxW each approx. 2.3 m) will be constructed. During radiation, the patient and theunit are in the chamber. The construction cost of this brachytherapy chamber with associated elements would not exceed the cost of making a classic brachytherapy treatment room.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora, A New Approach in the Construction of Protection in Brachytherapy – Brachytherapy Chamber",
pages = "313-320",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12183"
}
Stanković, J., Mirkov, Z., Dabić-Stanković, K., Obradović, Z.,& Rajković, K.. (2023). Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 313-320.
https://hdl.handle.net/21.15107/rcub_vinar_12183
Stanković J, Mirkov Z, Dabić-Stanković K, Obradović Z, Rajković K. Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora. in 32. simpozijum DZZSCG : zbornik radova. 2023;:313-320.
https://hdl.handle.net/21.15107/rcub_vinar_12183 .
Stanković, Jovan, Mirkov, Zoran, Dabić-Stanković, Kata, Obradović, Zorica, Rajković, Katarina, "Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora" in 32. simpozijum DZZSCG : zbornik radova (2023):313-320,
https://hdl.handle.net/21.15107/rcub_vinar_12183 .

Priprema radioaktivnih standarda za kalibraciju gama spektrometara

Vukanac, Ivana; Đurašević, Mirjana; Rajačić, Milica; Krneta Nikolić, Jelena; Sarap, Nataša; Janković, Marija

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Vukanac, Ivana
AU  - Đurašević, Mirjana
AU  - Rajačić, Milica
AU  - Krneta Nikolić, Jelena
AU  - Sarap, Nataša
AU  - Janković, Marija
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12182
AB  - Rutinska merenja uzoraka iz životne sredine gama spektrometrijom zahtevaju pripremu radioaktivnih standarda različitih matriksa. Radioaktivni standardi se koriste u svim fazama procesa merenja, uključujući validaciju metoda, kalibraciju i kontrolu kvaliteta. U Laboratoriji za Zaštitu od zračenja i zaštitu životne sredine, Instituta za nuklearne nauke „Vinča” radioaktivni standardi se pripremaju korišćenjem sertifikovanog radioaktivnog rastvora različitih radionuklida. U ovom radu je opisan postupak pripreme radioaktivnih standarda koji obuhvata izbor matriksa, pripremu i spajkovanje pripremljenih matriksa sa sertifikovanim radioaktivnim rastvorom, proveru homogenosti, pakovanje standarda u odgovarajuću geometriju i njihova merenja u kontakt geometriji na gama spektrometru. Za sve materijale matriksa pripremljeni su i uzorci „blenka“ i mereni u istoj geometriji kao i kalibracioni standardi. Nakon analize snimljenih spektara, fitovanjem datih tačaka efikasnosti dobijene su kalibracione krive. U ovom radu dat je i opis budžeta merne nesigurnosti za aktivnosti radionuklida prisutnih u pripremljenim standardima.
AB  - The routine measurements of environmental samples using gamma-ray spectrometry indicate the needs for preparing radioactive standards for various matrices. The radioactive standards are used in all phases of the measurement process, including method validation, calibration and quality control. In the Radiation and Environmental Protection Departmen in the "Vinča" Institute of Nuclear Sciences, radioactive standards are prepared using a certified radioactive solution of mixed radionuclides. The procedure for radioactive standards preparation, which includes matrix selection and preparation, spiking with a certified radioactive solution, homogeneity check, matrix packing in the appropriate geometry and measurement of the prepared standards using a gamma spectrometer, is described in this paper. For all matrix materials, "blank" samples were prepared in the same manner as the standard materials and measured in the same geometry as the calibration samples. After the analysis of recorded spectra and evaluation of the obtained data for efficiency at given energies, calibration curves were obtained by fitting. The uncertainty budget of the activity for all radionuclides present in the prepared standards is also defined in this paper.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Priprema radioaktivnih standarda za kalibraciju gama spektrometara
T1  - Preparation of Radioactive Standards for Calibration of Gamma Spectrometer
SP  - 272
EP  - 279
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12182
ER  - 
@conference{
author = "Vukanac, Ivana and Đurašević, Mirjana and Rajačić, Milica and Krneta Nikolić, Jelena and Sarap, Nataša and Janković, Marija",
year = "2023",
abstract = "Rutinska merenja uzoraka iz životne sredine gama spektrometrijom zahtevaju pripremu radioaktivnih standarda različitih matriksa. Radioaktivni standardi se koriste u svim fazama procesa merenja, uključujući validaciju metoda, kalibraciju i kontrolu kvaliteta. U Laboratoriji za Zaštitu od zračenja i zaštitu životne sredine, Instituta za nuklearne nauke „Vinča” radioaktivni standardi se pripremaju korišćenjem sertifikovanog radioaktivnog rastvora različitih radionuklida. U ovom radu je opisan postupak pripreme radioaktivnih standarda koji obuhvata izbor matriksa, pripremu i spajkovanje pripremljenih matriksa sa sertifikovanim radioaktivnim rastvorom, proveru homogenosti, pakovanje standarda u odgovarajuću geometriju i njihova merenja u kontakt geometriji na gama spektrometru. Za sve materijale matriksa pripremljeni su i uzorci „blenka“ i mereni u istoj geometriji kao i kalibracioni standardi. Nakon analize snimljenih spektara, fitovanjem datih tačaka efikasnosti dobijene su kalibracione krive. U ovom radu dat je i opis budžeta merne nesigurnosti za aktivnosti radionuklida prisutnih u pripremljenim standardima., The routine measurements of environmental samples using gamma-ray spectrometry indicate the needs for preparing radioactive standards for various matrices. The radioactive standards are used in all phases of the measurement process, including method validation, calibration and quality control. In the Radiation and Environmental Protection Departmen in the "Vinča" Institute of Nuclear Sciences, radioactive standards are prepared using a certified radioactive solution of mixed radionuclides. The procedure for radioactive standards preparation, which includes matrix selection and preparation, spiking with a certified radioactive solution, homogeneity check, matrix packing in the appropriate geometry and measurement of the prepared standards using a gamma spectrometer, is described in this paper. For all matrix materials, "blank" samples were prepared in the same manner as the standard materials and measured in the same geometry as the calibration samples. After the analysis of recorded spectra and evaluation of the obtained data for efficiency at given energies, calibration curves were obtained by fitting. The uncertainty budget of the activity for all radionuclides present in the prepared standards is also defined in this paper.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Priprema radioaktivnih standarda za kalibraciju gama spektrometara, Preparation of Radioactive Standards for Calibration of Gamma Spectrometer",
pages = "272-279",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12182"
}
Vukanac, I., Đurašević, M., Rajačić, M., Krneta Nikolić, J., Sarap, N.,& Janković, M.. (2023). Priprema radioaktivnih standarda za kalibraciju gama spektrometara. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 272-279.
https://hdl.handle.net/21.15107/rcub_vinar_12182
Vukanac I, Đurašević M, Rajačić M, Krneta Nikolić J, Sarap N, Janković M. Priprema radioaktivnih standarda za kalibraciju gama spektrometara. in 32. simpozijum DZZSCG : zbornik radova. 2023;:272-279.
https://hdl.handle.net/21.15107/rcub_vinar_12182 .
Vukanac, Ivana, Đurašević, Mirjana, Rajačić, Milica, Krneta Nikolić, Jelena, Sarap, Nataša, Janković, Marija, "Priprema radioaktivnih standarda za kalibraciju gama spektrometara" in 32. simpozijum DZZSCG : zbornik radova (2023):272-279,
https://hdl.handle.net/21.15107/rcub_vinar_12182 .

Merna nesigurnost ambijentalnih fotonskih dozimetara u impulsnom režimu rada sa posebnim osvrtom na uticaj osetljivosti detekcije i vremena merenja

Đaletić, Miloš

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Đaletić, Miloš
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12181
AB  - Procena merne nesigurnosti rezultata merenja ambijentalnog ekvivalenta doze gama zračenja značajna je za utvrđivanje adekvatnosti izabranog monitora zračenja i metode merenja. Neadekvatnim izborom monitora zračenja ili njegovim neoptimalnim korišćenjem, mogu se dostići velike vrednosti merne nesigurnosti. Uvek kad je moguće, treba izabrati odgovarajući monitor zračenja i mernu metodu. U ovom radu je procenjena merna nesigurnost za više tipova monitora zračenja sa veoma različitim mernim karakteristikama. Osetljivost detektora i odabrano vreme merenja u značajnoj meri utiču na mernu nesigurnost, što je na primerima i prikazano u ovom radu. Optimalnim izborom opreme i metode merenja mogu se dobiti značajno pouzdaniji rezultati merenja.
AB  - Assessment of the measurement uncertainty of the ambient dose equivalent is important for determining the adequacy of the selected survey meter and measurement method. Inadequate selection of the survey meter or its suboptimal use can result in high values of measurement uncertainty. Whenever possible, an appropriate survey meter and measurement method should be selected. In this paper, the measurement uncertainty was estimated for several types of survey meters with very different measurement characteristics. The sensitivity of the detector and the selected measurement time significantly affect the measurement uncertainty, which is shown in this paper with examples. Optimal selection of equipment and measurement method can provide significantly more reliable measurement results.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Merna nesigurnost ambijentalnih fotonskih dozimetara u impulsnom režimu rada sa posebnim osvrtom na uticaj osetljivosti detekcije i vremena merenja
T1  - Measurement Uncertainty of Ambient Photon Dosimeters in Pulse Mode Operation With Special Emphasis to the Influence of Detection Sensitivity and Measurement Time
SP  - 265
EP  - 271
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12181
ER  - 
@conference{
author = "Đaletić, Miloš",
year = "2023",
abstract = "Procena merne nesigurnosti rezultata merenja ambijentalnog ekvivalenta doze gama zračenja značajna je za utvrđivanje adekvatnosti izabranog monitora zračenja i metode merenja. Neadekvatnim izborom monitora zračenja ili njegovim neoptimalnim korišćenjem, mogu se dostići velike vrednosti merne nesigurnosti. Uvek kad je moguće, treba izabrati odgovarajući monitor zračenja i mernu metodu. U ovom radu je procenjena merna nesigurnost za više tipova monitora zračenja sa veoma različitim mernim karakteristikama. Osetljivost detektora i odabrano vreme merenja u značajnoj meri utiču na mernu nesigurnost, što je na primerima i prikazano u ovom radu. Optimalnim izborom opreme i metode merenja mogu se dobiti značajno pouzdaniji rezultati merenja., Assessment of the measurement uncertainty of the ambient dose equivalent is important for determining the adequacy of the selected survey meter and measurement method. Inadequate selection of the survey meter or its suboptimal use can result in high values of measurement uncertainty. Whenever possible, an appropriate survey meter and measurement method should be selected. In this paper, the measurement uncertainty was estimated for several types of survey meters with very different measurement characteristics. The sensitivity of the detector and the selected measurement time significantly affect the measurement uncertainty, which is shown in this paper with examples. Optimal selection of equipment and measurement method can provide significantly more reliable measurement results.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Merna nesigurnost ambijentalnih fotonskih dozimetara u impulsnom režimu rada sa posebnim osvrtom na uticaj osetljivosti detekcije i vremena merenja, Measurement Uncertainty of Ambient Photon Dosimeters in Pulse Mode Operation With Special Emphasis to the Influence of Detection Sensitivity and Measurement Time",
pages = "265-271",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12181"
}
Đaletić, M.. (2023). Merna nesigurnost ambijentalnih fotonskih dozimetara u impulsnom režimu rada sa posebnim osvrtom na uticaj osetljivosti detekcije i vremena merenja. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 265-271.
https://hdl.handle.net/21.15107/rcub_vinar_12181
Đaletić M. Merna nesigurnost ambijentalnih fotonskih dozimetara u impulsnom režimu rada sa posebnim osvrtom na uticaj osetljivosti detekcije i vremena merenja. in 32. simpozijum DZZSCG : zbornik radova. 2023;:265-271.
https://hdl.handle.net/21.15107/rcub_vinar_12181 .
Đaletić, Miloš, "Merna nesigurnost ambijentalnih fotonskih dozimetara u impulsnom režimu rada sa posebnim osvrtom na uticaj osetljivosti detekcije i vremena merenja" in 32. simpozijum DZZSCG : zbornik radova (2023):265-271,
https://hdl.handle.net/21.15107/rcub_vinar_12181 .

Rezultati ispitivanja sonde S1 sa kompenzacionim filterom za merenje ambijentalnog ekvivalenta doze za uređaj DMRZ-M15

Đaletić, Miloš; Komatina, Ivana

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Đaletić, Miloš
AU  - Komatina, Ivana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12180
AB  - Stupanjem na snagu Pravilnika o aktivnim dozimetrima fotonskog zračenja koji se koriste u zaštiti od jonizujućeg zračenja ("Sl. glasnik RS", br. 144/2022) propisani su zahtevi za aktivne dozimetre koji se koriste u funkciji zaštite zdravlja ljudi i životne sredine. Kako bi se poboljšale merne karakteristike sonde S1, uređaja DMRZ-M15, razvijen je kompenzacioni filter u obliku dodatnog poklopca sonde, oznake P2, koji se koristi tokom merenja ambijentalnog ekvivalenta doze. Zadržana je mogućnost postavljanja tankog zaštitnog poklopca oznake P1 ili potpunog uklanjanja poklopca kada se sonda ne koristi za merenje jačine doze, već samo kao detektor zračenja za otkrivanje izvora i kontaminacije. Na ovaj način je očuvana dobra osetljivost detekcije β i γ zračenja uz poboljšanje mernih karakteristika kada se uređaj koristi kao dozimetar. U radu su prikazani rezultati ispitivanja.
AB  - With the entry into force of the Rulebook on active photon radiation dosimeters used in protection against ionizing radiation ("Sl. glasnik RS", br. 144/2022), requirements for active dosimeters used in the function of protecting human health and the environment are defined. In order to improve the measurement characteristics of probe S1 used with the DMRZ-M15 survey meter, a compensation filter was developed in the form of an additional probe window cover, marked P2, which is used during the measurement of the ambient dose equivalent. The option of fitting a thin protective probe window cover marked P1 or removing the cover completely is retained when the probe is not used for dose rate measurement, but only as a radiation detector for source and contamination detection. In this way, the good sensitivity of detection of β and γ radiation is preserved while improving the measurement characteristics when the device is used as a dosimeter. The paper presents the test results.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Rezultati ispitivanja sonde S1 sa kompenzacionim filterom za merenje ambijentalnog ekvivalenta doze za uređaj DMRZ-M15
T1  - Test Results of Probe S1 With Compensation Filter for Measuring the Ambient Equivalent Dose Used With DMRZ-M15 Survey Meter
SP  - 259
EP  - 264
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12180
ER  - 
@conference{
author = "Đaletić, Miloš and Komatina, Ivana",
year = "2023",
abstract = "Stupanjem na snagu Pravilnika o aktivnim dozimetrima fotonskog zračenja koji se koriste u zaštiti od jonizujućeg zračenja ("Sl. glasnik RS", br. 144/2022) propisani su zahtevi za aktivne dozimetre koji se koriste u funkciji zaštite zdravlja ljudi i životne sredine. Kako bi se poboljšale merne karakteristike sonde S1, uređaja DMRZ-M15, razvijen je kompenzacioni filter u obliku dodatnog poklopca sonde, oznake P2, koji se koristi tokom merenja ambijentalnog ekvivalenta doze. Zadržana je mogućnost postavljanja tankog zaštitnog poklopca oznake P1 ili potpunog uklanjanja poklopca kada se sonda ne koristi za merenje jačine doze, već samo kao detektor zračenja za otkrivanje izvora i kontaminacije. Na ovaj način je očuvana dobra osetljivost detekcije β i γ zračenja uz poboljšanje mernih karakteristika kada se uređaj koristi kao dozimetar. U radu su prikazani rezultati ispitivanja., With the entry into force of the Rulebook on active photon radiation dosimeters used in protection against ionizing radiation ("Sl. glasnik RS", br. 144/2022), requirements for active dosimeters used in the function of protecting human health and the environment are defined. In order to improve the measurement characteristics of probe S1 used with the DMRZ-M15 survey meter, a compensation filter was developed in the form of an additional probe window cover, marked P2, which is used during the measurement of the ambient dose equivalent. The option of fitting a thin protective probe window cover marked P1 or removing the cover completely is retained when the probe is not used for dose rate measurement, but only as a radiation detector for source and contamination detection. In this way, the good sensitivity of detection of β and γ radiation is preserved while improving the measurement characteristics when the device is used as a dosimeter. The paper presents the test results.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Rezultati ispitivanja sonde S1 sa kompenzacionim filterom za merenje ambijentalnog ekvivalenta doze za uređaj DMRZ-M15, Test Results of Probe S1 With Compensation Filter for Measuring the Ambient Equivalent Dose Used With DMRZ-M15 Survey Meter",
pages = "259-264",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12180"
}
Đaletić, M.,& Komatina, I.. (2023). Rezultati ispitivanja sonde S1 sa kompenzacionim filterom za merenje ambijentalnog ekvivalenta doze za uređaj DMRZ-M15. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 259-264.
https://hdl.handle.net/21.15107/rcub_vinar_12180
Đaletić M, Komatina I. Rezultati ispitivanja sonde S1 sa kompenzacionim filterom za merenje ambijentalnog ekvivalenta doze za uređaj DMRZ-M15. in 32. simpozijum DZZSCG : zbornik radova. 2023;:259-264.
https://hdl.handle.net/21.15107/rcub_vinar_12180 .
Đaletić, Miloš, Komatina, Ivana, "Rezultati ispitivanja sonde S1 sa kompenzacionim filterom za merenje ambijentalnog ekvivalenta doze za uređaj DMRZ-M15" in 32. simpozijum DZZSCG : zbornik radova (2023):259-264,
https://hdl.handle.net/21.15107/rcub_vinar_12180 .

Interna kontrola kvaliteta HPGe gamaspektrometrijskog sistema

Samolov, Aleksandra; Kandić, Aleksandar; Đurašević, Mirjana; Čeliković, Igor; Milanović, Tamara; Vukanac, Ivana

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Samolov, Aleksandra
AU  - Kandić, Aleksandar
AU  - Đurašević, Mirjana
AU  - Čeliković, Igor
AU  - Milanović, Tamara
AU  - Vukanac, Ivana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12179
AB  - Kontrola kvaliteta laboratorijskog procesa zauzima značajno mesto u svakodnevnom laboratorijskom radu. Obzirom na važnost, međunarodni standardi su propisali načine i zahteve za vršenje ovakve kontrole. Jedan od zahteva standarda ISO 17025 je obezbeđenje poverenja u rezultate merenja, koje se, između ostalog, može vršiti kontinuiranim praćenjem parametara karakterističnih za laboratorijsku metodu od interesa preko konstruisanja tzv. kontrolnih karti. U radu su prikazani rezultati troipogodišnje analize rada gamaspektrometrijskog sistema u Laboratoriji za nuklearnu i plazma fiziku INN „Vinča“. Merenja su vršena jednom nedeljno a kao kontrolni izvori korišćeni su tačkasti izvori Co-60 i Cs-137. Pored praćenja odbroja ispod pika, položaja pika, širine na polovini visine pika (FWHM), širine na desetini visine pika (FWTM), kao i njihovog međusobnog odnosa (FWTM/FWHM), praćen je i odbroj u fonu. Rezultati su pokazali da gamaspektrometrijski sistem ima zadovoljavajuću stabilnost u radu u dužem vremenskom periodu.
AB  - Quality control of the laboratory process plays an important role in daily laboratory work. Due to its importance, international standards have issued the ways and requirements for performing such a task. One of the requirements of the ISO 17025 standard is to ensure confidence in the measurement results, which, among other things, can be done by continuously monitoring the parameters characteristic of the laboratory method of interest through the construction of the so-called control charts. The paper presents the results of a three-and-a-half-year analysis of the gamma spectrometric system measurements in the Laboratory for Nuclear and Plasma Physics of the INN "Vinča". Measurements were made once a week and point sources Co-60 and Cs-137 were used as control sources. In addition to monitoring the count below the peak, the position of the peak, the full width at half maximum (FWHM), the full width at tenth maximum (FWTM), as well as their mutual ratio (FWTM/FWHM), the count in the background was also monitored. The results show that the gamma spectrometric system has satisfactory stability over a long period of time.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Interna kontrola kvaliteta HPGe gamaspektrometrijskog sistema
T1  - Internal Quality Control of HPGe Gamma Spectrometry System
SP  - 232
EP  - 237
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12179
ER  - 
@conference{
author = "Samolov, Aleksandra and Kandić, Aleksandar and Đurašević, Mirjana and Čeliković, Igor and Milanović, Tamara and Vukanac, Ivana",
year = "2023",
abstract = "Kontrola kvaliteta laboratorijskog procesa zauzima značajno mesto u svakodnevnom laboratorijskom radu. Obzirom na važnost, međunarodni standardi su propisali načine i zahteve za vršenje ovakve kontrole. Jedan od zahteva standarda ISO 17025 je obezbeđenje poverenja u rezultate merenja, koje se, između ostalog, može vršiti kontinuiranim praćenjem parametara karakterističnih za laboratorijsku metodu od interesa preko konstruisanja tzv. kontrolnih karti. U radu su prikazani rezultati troipogodišnje analize rada gamaspektrometrijskog sistema u Laboratoriji za nuklearnu i plazma fiziku INN „Vinča“. Merenja su vršena jednom nedeljno a kao kontrolni izvori korišćeni su tačkasti izvori Co-60 i Cs-137. Pored praćenja odbroja ispod pika, položaja pika, širine na polovini visine pika (FWHM), širine na desetini visine pika (FWTM), kao i njihovog međusobnog odnosa (FWTM/FWHM), praćen je i odbroj u fonu. Rezultati su pokazali da gamaspektrometrijski sistem ima zadovoljavajuću stabilnost u radu u dužem vremenskom periodu., Quality control of the laboratory process plays an important role in daily laboratory work. Due to its importance, international standards have issued the ways and requirements for performing such a task. One of the requirements of the ISO 17025 standard is to ensure confidence in the measurement results, which, among other things, can be done by continuously monitoring the parameters characteristic of the laboratory method of interest through the construction of the so-called control charts. The paper presents the results of a three-and-a-half-year analysis of the gamma spectrometric system measurements in the Laboratory for Nuclear and Plasma Physics of the INN "Vinča". Measurements were made once a week and point sources Co-60 and Cs-137 were used as control sources. In addition to monitoring the count below the peak, the position of the peak, the full width at half maximum (FWHM), the full width at tenth maximum (FWTM), as well as their mutual ratio (FWTM/FWHM), the count in the background was also monitored. The results show that the gamma spectrometric system has satisfactory stability over a long period of time.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Interna kontrola kvaliteta HPGe gamaspektrometrijskog sistema, Internal Quality Control of HPGe Gamma Spectrometry System",
pages = "232-237",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12179"
}
Samolov, A., Kandić, A., Đurašević, M., Čeliković, I., Milanović, T.,& Vukanac, I.. (2023). Interna kontrola kvaliteta HPGe gamaspektrometrijskog sistema. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 232-237.
https://hdl.handle.net/21.15107/rcub_vinar_12179
Samolov A, Kandić A, Đurašević M, Čeliković I, Milanović T, Vukanac I. Interna kontrola kvaliteta HPGe gamaspektrometrijskog sistema. in 32. simpozijum DZZSCG : zbornik radova. 2023;:232-237.
https://hdl.handle.net/21.15107/rcub_vinar_12179 .
Samolov, Aleksandra, Kandić, Aleksandar, Đurašević, Mirjana, Čeliković, Igor, Milanović, Tamara, Vukanac, Ivana, "Interna kontrola kvaliteta HPGe gamaspektrometrijskog sistema" in 32. simpozijum DZZSCG : zbornik radova (2023):232-237,
https://hdl.handle.net/21.15107/rcub_vinar_12179 .

TraceRadon projekat – pregled najvažnijih rezultata

Čeliković, Igor; Vukanac, Ivana; Pantelić, Gordana; Živanović, Miloš; Krneta Nikolić, Jelena

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Čeliković, Igor
AU  - Vukanac, Ivana
AU  - Pantelić, Gordana
AU  - Živanović, Miloš
AU  - Krneta Nikolić, Jelena
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12178
AB  - Oko pola efektivne doze koju stanovništvo primi usled izlaganja jonizujućem zračenju potiče od radona i njegovih potomaka, te je problematika radona važna u oblasti zaštite od zračenja. Takođe, kao hemijski inertan gas, radon je našao primenu u izučavanju životne sredine kao traser za razne geološke i atmosferske procese. Jedna od važnih primena radona je u problematici praćenja gasova koji izazivaju efekat staklene bašte (greenhouse gases – GHG). Pokazano je da se poznavanjem fluksa radona iz zemlje i priraštaja koncentracije radona i koncentracije GHG u istom vremenskom intervalu tokom noći može odrediti fluks GHG. U ovom radu će biti prikazani odabrani rezultati nedavno završenog traceRadon projekta čiji je cilj bio razvijanje metrološki sledivih metoda merenja niskih koncentracija radona u atmosferi u granicama od 1 Bq m-3 do 100 Bq m-3, kao i unapređenje tehnika merenja i samo merenje radonskog fluksa, što će doprineti ispitivanju klimatskih promena kroz obezbeđivanje pouzdane procene fluksa GHG. Takođe, u sklopu projekta, vršila se procena do koje mere se radon u spoljašnjoj sredini i radonski fluks mogu koristiti za procenu radonskih prioritetnih oblasti.
AB  - Since more than a half of the effective doses from all ionising radiation come from the exposure to radon and its progeny, radon is important in the field of radiation protection. Being a noble gas and therefore chemically inert, radon is also used as a tracer for different geological and atmospheric processes. Radon is of interest to climate scientists for monitoring greenhouse gasses (GHG). It is known that by knowing radon flux and variation of radon and GHG concentration at the same period of time during the night, it is possible to estimate emission of GHG. In this paper, the most important results of recently finished EMPIR project 19ENV01 traceRadon “Radon metrology for use in climate change observation and radiation protection at the environmental level” are presented. Project aimed to develop the capability to measure SI traceable radon activity in the range of 1 Bq m-3 to 100 Bq m-3, suitable for outdoor radon measurements, to develop the capability for traceable radon flux measurements in the field which is important for GHG emission estimates and validation of contemporary radon flux models. Within the project it was investigated to what extent radon flux and outdoor radon data could be used for estimation of radon priority areas.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - TraceRadon projekat – pregled najvažnijih rezultata
T1  - TraceRadon Project – An Overview of Scientific Achievements
SP  - 196
EP  - 205
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12178
ER  - 
@conference{
author = "Čeliković, Igor and Vukanac, Ivana and Pantelić, Gordana and Živanović, Miloš and Krneta Nikolić, Jelena",
year = "2023",
abstract = "Oko pola efektivne doze koju stanovništvo primi usled izlaganja jonizujućem zračenju potiče od radona i njegovih potomaka, te je problematika radona važna u oblasti zaštite od zračenja. Takođe, kao hemijski inertan gas, radon je našao primenu u izučavanju životne sredine kao traser za razne geološke i atmosferske procese. Jedna od važnih primena radona je u problematici praćenja gasova koji izazivaju efekat staklene bašte (greenhouse gases – GHG). Pokazano je da se poznavanjem fluksa radona iz zemlje i priraštaja koncentracije radona i koncentracije GHG u istom vremenskom intervalu tokom noći može odrediti fluks GHG. U ovom radu će biti prikazani odabrani rezultati nedavno završenog traceRadon projekta čiji je cilj bio razvijanje metrološki sledivih metoda merenja niskih koncentracija radona u atmosferi u granicama od 1 Bq m-3 do 100 Bq m-3, kao i unapređenje tehnika merenja i samo merenje radonskog fluksa, što će doprineti ispitivanju klimatskih promena kroz obezbeđivanje pouzdane procene fluksa GHG. Takođe, u sklopu projekta, vršila se procena do koje mere se radon u spoljašnjoj sredini i radonski fluks mogu koristiti za procenu radonskih prioritetnih oblasti., Since more than a half of the effective doses from all ionising radiation come from the exposure to radon and its progeny, radon is important in the field of radiation protection. Being a noble gas and therefore chemically inert, radon is also used as a tracer for different geological and atmospheric processes. Radon is of interest to climate scientists for monitoring greenhouse gasses (GHG). It is known that by knowing radon flux and variation of radon and GHG concentration at the same period of time during the night, it is possible to estimate emission of GHG. In this paper, the most important results of recently finished EMPIR project 19ENV01 traceRadon “Radon metrology for use in climate change observation and radiation protection at the environmental level” are presented. Project aimed to develop the capability to measure SI traceable radon activity in the range of 1 Bq m-3 to 100 Bq m-3, suitable for outdoor radon measurements, to develop the capability for traceable radon flux measurements in the field which is important for GHG emission estimates and validation of contemporary radon flux models. Within the project it was investigated to what extent radon flux and outdoor radon data could be used for estimation of radon priority areas.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "TraceRadon projekat – pregled najvažnijih rezultata, TraceRadon Project – An Overview of Scientific Achievements",
pages = "196-205",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12178"
}
Čeliković, I., Vukanac, I., Pantelić, G., Živanović, M.,& Krneta Nikolić, J.. (2023). TraceRadon projekat – pregled najvažnijih rezultata. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 196-205.
https://hdl.handle.net/21.15107/rcub_vinar_12178
Čeliković I, Vukanac I, Pantelić G, Živanović M, Krneta Nikolić J. TraceRadon projekat – pregled najvažnijih rezultata. in 32. simpozijum DZZSCG : zbornik radova. 2023;:196-205.
https://hdl.handle.net/21.15107/rcub_vinar_12178 .
Čeliković, Igor, Vukanac, Ivana, Pantelić, Gordana, Živanović, Miloš, Krneta Nikolić, Jelena, "TraceRadon projekat – pregled najvažnijih rezultata" in 32. simpozijum DZZSCG : zbornik radova (2023):196-205,
https://hdl.handle.net/21.15107/rcub_vinar_12178 .

Merenje koncentracije radona u zatvorenom prostoru – prikaz jednog slučaja

Arsić, Vesna; Čeliković, Igor; Tanasković, Irena; Bogojević, Suzana; Ilić, Jovana

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Arsić, Vesna
AU  - Čeliković, Igor
AU  - Tanasković, Irena
AU  - Bogojević, Suzana
AU  - Ilić, Jovana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12177
AB  - Laboratorija za merenje radioaktivnosti Instituta za medicinu rada Srbije “Dr Dragomir Karajović” je prvobitnim merenjem koncentracije radona pomoću kanistera sa aktivnim ugljem, u privatnoj kući na Bežanijskoj Kosi u Beogradu, ustanovila povišenu koncentraciju u novom delu kuće. U cilju utvrđivanja razloga povišene koncentracije radona, nova merenja su organizovana u još tri navrata (etape), u različitim periodima, pokrivajući sva četiri godišnja doba. Rad predstavlja prikaz ovog slučaja u kom je pored pomenute laboratorije učestvovala i Laboratorija za nuklearnu i plazma fiziku Instituta “Vinča” uz kombinovanje većeg broja metoda: merenje koncentracije radona pomoću kanistera sa aktivnim ugljem, pomoću aktivnog uređaja – alfaspektrometra, određivanje koncentracije radona na osnovu ekshalacije radona iz poda prostorije i građjevinskog materijala, na osnovu merenja koncentracije radona u zemljištu, na osnovu gamaspektrometrijske analize zemljišta uzorkovanog iz dvorišta ispred kuće. Analizom dobijenih rezultata potvrđena su dosadašnja saznanja o dnevnim i sezonskim varijacijama koncentracije radona.
AB  - The Radioactivity Measurement Laboratory has initially measured the radon concentration, in a private house on Bežanijska Kosa in Belgrade, by activated charcoal canisters and established a high concentration in the new part of the house. In order to determine the reasons for the increased radon concentration, new measurements were organized three more times, in different periods, covering all four seasons. This paper presents a report of these measurements in which, the Nuclear And Plasma Physics Laboratory Of The "Vinca" Institute also participated with the combination of a larger number of methods: radon concentration measurement by activated charcoal canisters, radon concentration measurement by active device – alpha-spectrometer, determination of radon concentrations on the basis of radon exhalation rate from the floor of the room, from the building material, on the basis of the radon measurement from the soil, estimation of radon concentration on the basis of gamma spectrometry analysis of the soil sample, taken from the yard in front of the house. Analysis of the obtained results confirmed previous knowledge about seasonal and others variations in radon concentration.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Merenje koncentracije radona u zatvorenom prostoru – prikaz jednog slučaja
T1  - Indoor Radon Concentration Measurement - Case Study
SP  - 186
EP  - 195
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12177
ER  - 
@conference{
author = "Arsić, Vesna and Čeliković, Igor and Tanasković, Irena and Bogojević, Suzana and Ilić, Jovana",
year = "2023",
abstract = "Laboratorija za merenje radioaktivnosti Instituta za medicinu rada Srbije “Dr Dragomir Karajović” je prvobitnim merenjem koncentracije radona pomoću kanistera sa aktivnim ugljem, u privatnoj kući na Bežanijskoj Kosi u Beogradu, ustanovila povišenu koncentraciju u novom delu kuće. U cilju utvrđivanja razloga povišene koncentracije radona, nova merenja su organizovana u još tri navrata (etape), u različitim periodima, pokrivajući sva četiri godišnja doba. Rad predstavlja prikaz ovog slučaja u kom je pored pomenute laboratorije učestvovala i Laboratorija za nuklearnu i plazma fiziku Instituta “Vinča” uz kombinovanje većeg broja metoda: merenje koncentracije radona pomoću kanistera sa aktivnim ugljem, pomoću aktivnog uređaja – alfaspektrometra, određivanje koncentracije radona na osnovu ekshalacije radona iz poda prostorije i građjevinskog materijala, na osnovu merenja koncentracije radona u zemljištu, na osnovu gamaspektrometrijske analize zemljišta uzorkovanog iz dvorišta ispred kuće. Analizom dobijenih rezultata potvrđena su dosadašnja saznanja o dnevnim i sezonskim varijacijama koncentracije radona., The Radioactivity Measurement Laboratory has initially measured the radon concentration, in a private house on Bežanijska Kosa in Belgrade, by activated charcoal canisters and established a high concentration in the new part of the house. In order to determine the reasons for the increased radon concentration, new measurements were organized three more times, in different periods, covering all four seasons. This paper presents a report of these measurements in which, the Nuclear And Plasma Physics Laboratory Of The "Vinca" Institute also participated with the combination of a larger number of methods: radon concentration measurement by activated charcoal canisters, radon concentration measurement by active device – alpha-spectrometer, determination of radon concentrations on the basis of radon exhalation rate from the floor of the room, from the building material, on the basis of the radon measurement from the soil, estimation of radon concentration on the basis of gamma spectrometry analysis of the soil sample, taken from the yard in front of the house. Analysis of the obtained results confirmed previous knowledge about seasonal and others variations in radon concentration.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Merenje koncentracije radona u zatvorenom prostoru – prikaz jednog slučaja, Indoor Radon Concentration Measurement - Case Study",
pages = "186-195",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12177"
}
Arsić, V., Čeliković, I., Tanasković, I., Bogojević, S.,& Ilić, J.. (2023). Merenje koncentracije radona u zatvorenom prostoru – prikaz jednog slučaja. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 186-195.
https://hdl.handle.net/21.15107/rcub_vinar_12177
Arsić V, Čeliković I, Tanasković I, Bogojević S, Ilić J. Merenje koncentracije radona u zatvorenom prostoru – prikaz jednog slučaja. in 32. simpozijum DZZSCG : zbornik radova. 2023;:186-195.
https://hdl.handle.net/21.15107/rcub_vinar_12177 .
Arsić, Vesna, Čeliković, Igor, Tanasković, Irena, Bogojević, Suzana, Ilić, Jovana, "Merenje koncentracije radona u zatvorenom prostoru – prikaz jednog slučaja" in 32. simpozijum DZZSCG : zbornik radova (2023):186-195,
https://hdl.handle.net/21.15107/rcub_vinar_12177 .

Soil to Plant Transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in Different Agricultural Products in Croatia

Skoko, Božena; Karanović, Gorana; Ilievski, Tomislav; Coha, Ivana; Grahek, Željko; Magdić Košiček, Katja; Smičiklas, Ivana; Pavičić-Hamer, Dijana; Tucaković, Ivana

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Skoko, Božena
AU  - Karanović, Gorana
AU  - Ilievski, Tomislav
AU  - Coha, Ivana
AU  - Grahek, Željko
AU  - Magdić Košiček, Katja
AU  - Smičiklas, Ivana
AU  - Pavičić-Hamer, Dijana
AU  - Tucaković, Ivana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12176
AB  - In this study, we investigated the soil-to-plant transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in different types of vegetables and fruits collected on family farms in Croatia. The difference in radionuclide distribution between different plant compartments was also investigated. Our results suggest that, in general, the transfer of selected radionuclides within studied soil/plant agricultural ecosystems is on the lower part of ranges reported by IAEA for the temperate environments. Nevertheless, for all studied radionuclides, the transfer to the fruits and vegetables peels was higher than to the pulp. Overall, observed differences in the transfer of radionuclides indicate other additional exposure pathways and mechanisms that affect radionuclide content in plants besides soil activity concentrations.
AB  - U ovom smo radu istražili prijenos Cs-137, Sr-90, Ra-226, Pb-210 te K-40 iz tla u različite vrste povrća i voća sakupljenih na obiteljskim poljoprivrednim imanjima u Hrvatskoj. Istovremeno su istražene i razlike u prijenosu radionuklida u različite dijelove plodova. Rezultati ovog istraživanja ukazuju da je generalno prijenos radionuklida obuhvaćenih ovom studijom unutar raspona transfer faktora sugeriranih od strane IAEA za umjerena područja, ali na njihovom nižem dijelu. Unatoč nižem transferu, uočen je povišeni prijenos svih istraživanih radionuklida u kore plodova u odnosu na pulpu. Sveukupno, primjećene razlike u prijenosu radionuklida sugeriraju, osim sadržaja radionuklida u tlu, i druge mehanizme i puteve izlaganja radionuklidima, a koje utječu na njihove količine u biljkama.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Soil to Plant Transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in Different Agricultural Products in Croatia
T1  - Prijenos Cs-137, Sr-90, Ra-226, Pb-210 i K-40 iz tla u biljku u različitim poljoprivrednim kulturama u Hrvatskoj
SP  - 153
EP  - 159
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12176
ER  - 
@conference{
author = "Skoko, Božena and Karanović, Gorana and Ilievski, Tomislav and Coha, Ivana and Grahek, Željko and Magdić Košiček, Katja and Smičiklas, Ivana and Pavičić-Hamer, Dijana and Tucaković, Ivana",
year = "2023",
abstract = "In this study, we investigated the soil-to-plant transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in different types of vegetables and fruits collected on family farms in Croatia. The difference in radionuclide distribution between different plant compartments was also investigated. Our results suggest that, in general, the transfer of selected radionuclides within studied soil/plant agricultural ecosystems is on the lower part of ranges reported by IAEA for the temperate environments. Nevertheless, for all studied radionuclides, the transfer to the fruits and vegetables peels was higher than to the pulp. Overall, observed differences in the transfer of radionuclides indicate other additional exposure pathways and mechanisms that affect radionuclide content in plants besides soil activity concentrations., U ovom smo radu istražili prijenos Cs-137, Sr-90, Ra-226, Pb-210 te K-40 iz tla u različite vrste povrća i voća sakupljenih na obiteljskim poljoprivrednim imanjima u Hrvatskoj. Istovremeno su istražene i razlike u prijenosu radionuklida u različite dijelove plodova. Rezultati ovog istraživanja ukazuju da je generalno prijenos radionuklida obuhvaćenih ovom studijom unutar raspona transfer faktora sugeriranih od strane IAEA za umjerena područja, ali na njihovom nižem dijelu. Unatoč nižem transferu, uočen je povišeni prijenos svih istraživanih radionuklida u kore plodova u odnosu na pulpu. Sveukupno, primjećene razlike u prijenosu radionuklida sugeriraju, osim sadržaja radionuklida u tlu, i druge mehanizme i puteve izlaganja radionuklidima, a koje utječu na njihove količine u biljkama.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Soil to Plant Transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in Different Agricultural Products in Croatia, Prijenos Cs-137, Sr-90, Ra-226, Pb-210 i K-40 iz tla u biljku u različitim poljoprivrednim kulturama u Hrvatskoj",
pages = "153-159",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12176"
}
Skoko, B., Karanović, G., Ilievski, T., Coha, I., Grahek, Ž., Magdić Košiček, K., Smičiklas, I., Pavičić-Hamer, D.,& Tucaković, I.. (2023). Soil to Plant Transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in Different Agricultural Products in Croatia. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 153-159.
https://hdl.handle.net/21.15107/rcub_vinar_12176
Skoko B, Karanović G, Ilievski T, Coha I, Grahek Ž, Magdić Košiček K, Smičiklas I, Pavičić-Hamer D, Tucaković I. Soil to Plant Transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in Different Agricultural Products in Croatia. in 32. simpozijum DZZSCG : zbornik radova. 2023;:153-159.
https://hdl.handle.net/21.15107/rcub_vinar_12176 .
Skoko, Božena, Karanović, Gorana, Ilievski, Tomislav, Coha, Ivana, Grahek, Željko, Magdić Košiček, Katja, Smičiklas, Ivana, Pavičić-Hamer, Dijana, Tucaković, Ivana, "Soil to Plant Transfer of Cs-137, Sr-90, Ra-226, Pb-210 and K-40 in Different Agricultural Products in Croatia" in 32. simpozijum DZZSCG : zbornik radova (2023):153-159,
https://hdl.handle.net/21.15107/rcub_vinar_12176 .

Izbor referentnog datuma za prezentovanje aktivnosti radionuklida u vremenski kompozitnim uzorcima

Rajačić, Milica; Vukanac, Ivana; Krneta Nikolić, Jelena; Sarap, Nataša; Janković, Marija

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Rajačić, Milica
AU  - Vukanac, Ivana
AU  - Krneta Nikolić, Jelena
AU  - Sarap, Nataša
AU  - Janković, Marija
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12175
AB  - Pitanje kojim se ovaj rad bavi je: “Kako predstaviti “dan uzorkovanja” kod vremenski kompozitnih uzoraka?”. Izbor referentnog datuma koji će predstaviti “dan uzorkovanja” je stvar dogovora, ali rezultati aktivnosti ispitanog radionuklida dati na različite referentne datume suštinski nisu međusobno poredivi. Cilj je bio da se ispita na koji dan korigovana izmerena aktivnost (Ar) najpribližnije određuje ukupnu dnevnu aktivnost svih uzorka na dan njihovog uzorkovanja (Au). Ispostavlja se da dan kada je razlika ove dve aktivnosi (Δ) minimalna zavisi od više faktora: ukupne vrednosti dnevnih aktivnosti (Au), vremenske raspodele dnevnih vrednosti (homogenost), dužine perioda sakupljanja (D) i vremena poluraspada posmatranog radionuklida (T1/2). Shodno tome, u radu je praćeno kako promena navedenih parametara utiče na promenu optimalnog referentnog datuma za koji je vrednost Δ minimalna (dan r). Rezultati pokazuju izvestan nivo pravilnosti kod homogenih uzoraka, međutim nehomogenost dnevnih aktivnosti, što je slučaj u realnosti, ima veliki uticaj na promenu optimalnog referentnog datuma, ali za sada bez utvrđenih pravilnosti.
AB  - The question that this paper deals with is: "How to present the "sampling day" in temporal composite samples?". The choice of the reference data that will represent the "sampling day" is a matter of agreement, but the results of the activity of the tested radionuclide given on different reference dates are essentially not mutually comparable. The aim of the paper was to examine on which day the corrected measured activity (Ar) most closely determines the total daily activity of all samples on the day of their sampling (Au). It turns out that the day when the difference between these two activities (Δ) is minimal depends on several factors: the total value of daily activities (Au), the temporal distribution of daily values (homogeneity), the length of the collection period (D) and the half-life of the observed radionuclide (T1/2 ). Accordingly, the influence of the variation of mentioned parameters on the change of the optimal reference date for which the value of Δ is minimal (day r) is presented in this paper. The results show some level of regularity in homogeneous samples, however, the inhomogeneity of daily activities, which is the case in reality, has a great influence on the change of the optimal reference date, but for now, without established consistency.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Izbor referentnog datuma za prezentovanje aktivnosti radionuklida u vremenski kompozitnim uzorcima
T1  - Selection of Reference Date for Presentation of Radionuclide Activity in Time-Composite Samples
SP  - 137
EP  - 142
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12175
ER  - 
@conference{
author = "Rajačić, Milica and Vukanac, Ivana and Krneta Nikolić, Jelena and Sarap, Nataša and Janković, Marija",
year = "2023",
abstract = "Pitanje kojim se ovaj rad bavi je: “Kako predstaviti “dan uzorkovanja” kod vremenski kompozitnih uzoraka?”. Izbor referentnog datuma koji će predstaviti “dan uzorkovanja” je stvar dogovora, ali rezultati aktivnosti ispitanog radionuklida dati na različite referentne datume suštinski nisu međusobno poredivi. Cilj je bio da se ispita na koji dan korigovana izmerena aktivnost (Ar) najpribližnije određuje ukupnu dnevnu aktivnost svih uzorka na dan njihovog uzorkovanja (Au). Ispostavlja se da dan kada je razlika ove dve aktivnosi (Δ) minimalna zavisi od više faktora: ukupne vrednosti dnevnih aktivnosti (Au), vremenske raspodele dnevnih vrednosti (homogenost), dužine perioda sakupljanja (D) i vremena poluraspada posmatranog radionuklida (T1/2). Shodno tome, u radu je praćeno kako promena navedenih parametara utiče na promenu optimalnog referentnog datuma za koji je vrednost Δ minimalna (dan r). Rezultati pokazuju izvestan nivo pravilnosti kod homogenih uzoraka, međutim nehomogenost dnevnih aktivnosti, što je slučaj u realnosti, ima veliki uticaj na promenu optimalnog referentnog datuma, ali za sada bez utvrđenih pravilnosti., The question that this paper deals with is: "How to present the "sampling day" in temporal composite samples?". The choice of the reference data that will represent the "sampling day" is a matter of agreement, but the results of the activity of the tested radionuclide given on different reference dates are essentially not mutually comparable. The aim of the paper was to examine on which day the corrected measured activity (Ar) most closely determines the total daily activity of all samples on the day of their sampling (Au). It turns out that the day when the difference between these two activities (Δ) is minimal depends on several factors: the total value of daily activities (Au), the temporal distribution of daily values (homogeneity), the length of the collection period (D) and the half-life of the observed radionuclide (T1/2 ). Accordingly, the influence of the variation of mentioned parameters on the change of the optimal reference date for which the value of Δ is minimal (day r) is presented in this paper. The results show some level of regularity in homogeneous samples, however, the inhomogeneity of daily activities, which is the case in reality, has a great influence on the change of the optimal reference date, but for now, without established consistency.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Izbor referentnog datuma za prezentovanje aktivnosti radionuklida u vremenski kompozitnim uzorcima, Selection of Reference Date for Presentation of Radionuclide Activity in Time-Composite Samples",
pages = "137-142",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12175"
}
Rajačić, M., Vukanac, I., Krneta Nikolić, J., Sarap, N.,& Janković, M.. (2023). Izbor referentnog datuma za prezentovanje aktivnosti radionuklida u vremenski kompozitnim uzorcima. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 137-142.
https://hdl.handle.net/21.15107/rcub_vinar_12175
Rajačić M, Vukanac I, Krneta Nikolić J, Sarap N, Janković M. Izbor referentnog datuma za prezentovanje aktivnosti radionuklida u vremenski kompozitnim uzorcima. in 32. simpozijum DZZSCG : zbornik radova. 2023;:137-142.
https://hdl.handle.net/21.15107/rcub_vinar_12175 .
Rajačić, Milica, Vukanac, Ivana, Krneta Nikolić, Jelena, Sarap, Nataša, Janković, Marija, "Izbor referentnog datuma za prezentovanje aktivnosti radionuklida u vremenski kompozitnim uzorcima" in 32. simpozijum DZZSCG : zbornik radova (2023):137-142,
https://hdl.handle.net/21.15107/rcub_vinar_12175 .

Fly-Ash for Usage in the Building Material Industry

Mladenović Nikolić, Nataša; Trivunac, Katarina; Nenadović, Miloš; Dolenec, Sabina; Mrak, Maruša; Vukanac, Ivana; Nenadović, Snežana; Kljajević, Ljiljana M.

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Mladenović Nikolić, Nataša
AU  - Trivunac, Katarina
AU  - Nenadović, Miloš
AU  - Dolenec, Sabina
AU  - Mrak, Maruša
AU  - Vukanac, Ivana
AU  - Nenadović, Snežana
AU  - Kljajević, Ljiljana M.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12174
AB  - In this study, fly ash (FA) from the active and passive cassette TENT A (Nikola Tesla power plant, Obrenovac) is characterized from physicochemical and radiological aspects.Samples of FA consisted of amorphous phase followed by quartz, mullite, plagioclase, K-feldspar, hematite and calcite. As indicated by laser granulometry, the fraction D50 of investigated samples are about 80μm, so based on the above, they belong to coarse ashes.Very important parameter which defines chemical composition of the fly ash as precursor material of clinker or alkali activated materialsis presence of organic matter which is expressed by total organic content (TOC).Assessment of radiation exposure during coal combustion depends on the concentration of radioactive elements in the coal and in the resulting fly ash. Fly ash as industrial waste contains certain concentrations of natural radionuclides that are considered naturally occurring radioactive materials (NORM). The results showed that fly ash has satisfactory radiological properties and can be used as an addition to clinkers, but also as a potential precursor of a new class of alkaline activated materials that can be used in the construction sector.
AB  - Procena izloženosti zračenju pri sagorevanju uglja zavisi od koncentracije radioaktivnih elemenata u uglju i u letećem pepelu koji nastaje. Uzorci letećeg pepela se sastoje od amorfne faze praćene kvarcom, mulitom, plagioklasom, K-feldspatom, hematinom, kalcitom. Kao rezultat laserske granulometrije, frakcija D50 za ispitivane uzorke je približno 80 μm, tako da na osnovu navedenog, leteći pepeli predstavljaju pepele krupnih čestica. Veoma važan parametar je prisustvo organske materije koje se izražava ukupnim organskim sadržajem. Leteći pepeli kao industrijski ostaci sadrže određene koncentracije prirodnih radionuklida koji se smatraju prirodnim radioaktivnim materijalima (NORM). U ovojm istraživanju, leteći pepeo iz aktivne i pasivne kasete TENT A (termoelektrana Nikola Tesla, Obrenovac) karakteriše se sa radiološkog i fizičko-hemijskog aspekta. Rezultati su pokazali da leteći pepeo ima zadovoljavajuća radiološka svojstva i da se može koristiti kao dodatak klinkerima, ali i kao potencijalni precursor nove klase alkalno aktiviranih materijala koji se mogu primeniti u građevinskom sektoru.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Fly-Ash for Usage in the Building Material Industry
T1  - Upotreba letećeg pepela u industriji građevinskog materijala
SP  - 128
EP  - 136
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12174
ER  - 
@conference{
author = "Mladenović Nikolić, Nataša and Trivunac, Katarina and Nenadović, Miloš and Dolenec, Sabina and Mrak, Maruša and Vukanac, Ivana and Nenadović, Snežana and Kljajević, Ljiljana M.",
year = "2023",
abstract = "In this study, fly ash (FA) from the active and passive cassette TENT A (Nikola Tesla power plant, Obrenovac) is characterized from physicochemical and radiological aspects.Samples of FA consisted of amorphous phase followed by quartz, mullite, plagioclase, K-feldspar, hematite and calcite. As indicated by laser granulometry, the fraction D50 of investigated samples are about 80μm, so based on the above, they belong to coarse ashes.Very important parameter which defines chemical composition of the fly ash as precursor material of clinker or alkali activated materialsis presence of organic matter which is expressed by total organic content (TOC).Assessment of radiation exposure during coal combustion depends on the concentration of radioactive elements in the coal and in the resulting fly ash. Fly ash as industrial waste contains certain concentrations of natural radionuclides that are considered naturally occurring radioactive materials (NORM). The results showed that fly ash has satisfactory radiological properties and can be used as an addition to clinkers, but also as a potential precursor of a new class of alkaline activated materials that can be used in the construction sector., Procena izloženosti zračenju pri sagorevanju uglja zavisi od koncentracije radioaktivnih elemenata u uglju i u letećem pepelu koji nastaje. Uzorci letećeg pepela se sastoje od amorfne faze praćene kvarcom, mulitom, plagioklasom, K-feldspatom, hematinom, kalcitom. Kao rezultat laserske granulometrije, frakcija D50 za ispitivane uzorke je približno 80 μm, tako da na osnovu navedenog, leteći pepeli predstavljaju pepele krupnih čestica. Veoma važan parametar je prisustvo organske materije koje se izražava ukupnim organskim sadržajem. Leteći pepeli kao industrijski ostaci sadrže određene koncentracije prirodnih radionuklida koji se smatraju prirodnim radioaktivnim materijalima (NORM). U ovojm istraživanju, leteći pepeo iz aktivne i pasivne kasete TENT A (termoelektrana Nikola Tesla, Obrenovac) karakteriše se sa radiološkog i fizičko-hemijskog aspekta. Rezultati su pokazali da leteći pepeo ima zadovoljavajuća radiološka svojstva i da se može koristiti kao dodatak klinkerima, ali i kao potencijalni precursor nove klase alkalno aktiviranih materijala koji se mogu primeniti u građevinskom sektoru.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Fly-Ash for Usage in the Building Material Industry, Upotreba letećeg pepela u industriji građevinskog materijala",
pages = "128-136",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12174"
}
Mladenović Nikolić, N., Trivunac, K., Nenadović, M., Dolenec, S., Mrak, M., Vukanac, I., Nenadović, S.,& Kljajević, L. M.. (2023). Fly-Ash for Usage in the Building Material Industry. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 128-136.
https://hdl.handle.net/21.15107/rcub_vinar_12174
Mladenović Nikolić N, Trivunac K, Nenadović M, Dolenec S, Mrak M, Vukanac I, Nenadović S, Kljajević LM. Fly-Ash for Usage in the Building Material Industry. in 32. simpozijum DZZSCG : zbornik radova. 2023;:128-136.
https://hdl.handle.net/21.15107/rcub_vinar_12174 .
Mladenović Nikolić, Nataša, Trivunac, Katarina, Nenadović, Miloš, Dolenec, Sabina, Mrak, Maruša, Vukanac, Ivana, Nenadović, Snežana, Kljajević, Ljiljana M., "Fly-Ash for Usage in the Building Material Industry" in 32. simpozijum DZZSCG : zbornik radova (2023):128-136,
https://hdl.handle.net/21.15107/rcub_vinar_12174 .