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Antidepressants- and antipsychotics-induced hepatotoxicity

Todorović Vukotić, Nevena; Đorđević, Jelena; Pejić, Snežana; Đorđević, Neda O.; Pajović, Snežana B.

(2021)

TY  - JOUR
AU  - Todorović Vukotić, Nevena
AU  - Đorđević, Jelena
AU  - Pejić, Snežana
AU  - Đorđević, Neda O.
AU  - Pajović, Snežana B.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9078
AB  - Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common comorbidities of psychiatric and metabolic disorders, and polypharmacy in psychiatric patients increase the incidence of psychotropics-induced DILI. During the last 2 decades, hepatotoxicity of various antidepressants (ADs) and antipsychotics (APs) received much attention. Comprehensive review and discussion of accumulated literature data concerning this issue are performed in this study, as hepatotoxic effects of most commonly prescribed ADs and APs are classified, described, and discussed. The review focuses on ADs and APs characterized by the risk of causing liver damage and highlights the ones found to cause life-threatening or severe DILI cases. In parallel, an overview of hepatic oxidative stress, inflammation, and steatosis underlying DILI is provided, followed by extensive review and discussion of the pathophysiology of AD- and AP-induced DILI revealed in case reports, and animal and in vitro studies. The consequences of some ADs and APs ability to affect drug-metabolizing enzymes and therefore provoke drug–drug interactions are also addressed. Continuous collecting of data on drugs, mechanisms, and risk factors for DILI, as well as critical data reviewing, is crucial for easier DILI diagnosis and more efficient risk assessment of AD- and AP-induced DILI. Higher awareness of ADs and APs hepatotoxicity is the prerequisite for their safe use and optimal dosing. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.
T2  - Archives of Toxicology
T1  - Antidepressants- and antipsychotics-induced hepatotoxicity
VL  - 95
IS  - 3
SP  - 767
EP  - 789
DO  - 10.1007/s00204-020-02963-4
ER  - 
@article{
author = "Todorović Vukotić, Nevena and Đorđević, Jelena and Pejić, Snežana and Đorđević, Neda O. and Pajović, Snežana B.",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9078",
abstract = "Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common comorbidities of psychiatric and metabolic disorders, and polypharmacy in psychiatric patients increase the incidence of psychotropics-induced DILI. During the last 2 decades, hepatotoxicity of various antidepressants (ADs) and antipsychotics (APs) received much attention. Comprehensive review and discussion of accumulated literature data concerning this issue are performed in this study, as hepatotoxic effects of most commonly prescribed ADs and APs are classified, described, and discussed. The review focuses on ADs and APs characterized by the risk of causing liver damage and highlights the ones found to cause life-threatening or severe DILI cases. In parallel, an overview of hepatic oxidative stress, inflammation, and steatosis underlying DILI is provided, followed by extensive review and discussion of the pathophysiology of AD- and AP-induced DILI revealed in case reports, and animal and in vitro studies. The consequences of some ADs and APs ability to affect drug-metabolizing enzymes and therefore provoke drug–drug interactions are also addressed. Continuous collecting of data on drugs, mechanisms, and risk factors for DILI, as well as critical data reviewing, is crucial for easier DILI diagnosis and more efficient risk assessment of AD- and AP-induced DILI. Higher awareness of ADs and APs hepatotoxicity is the prerequisite for their safe use and optimal dosing. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.",
journal = "Archives of Toxicology",
title = "Antidepressants- and antipsychotics-induced hepatotoxicity",
volume = "95",
number = "3",
pages = "767-789",
doi = "10.1007/s00204-020-02963-4"
}
Todorović Vukotić, N., Đorđević, J., Pejić, S., Đorđević, N. O.,& Pajović, S. B. (2021). Antidepressants- and antipsychotics-induced hepatotoxicity.
Archives of Toxicology, 95(3), 767-789.
https://doi.org/10.1007/s00204-020-02963-4
Todorović Vukotić N, Đorđević J, Pejić S, Đorđević NO, Pajović SB. Antidepressants- and antipsychotics-induced hepatotoxicity. Archives of Toxicology. 2021;95(3):767-789
Todorović Vukotić Nevena, Đorđević Jelena, Pejić Snežana, Đorđević Neda O., Pajović Snežana B., "Antidepressants- and antipsychotics-induced hepatotoxicity" Archives of Toxicology, 95, no. 3 (2021):767-789,
https://doi.org/10.1007/s00204-020-02963-4 .
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Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study

Dragojlović, Milijana; Milanović, Igor; Gradišek, Anton; Kurko, Sandra V.; Mitrić, Miodrag; Umićević, Ana; Radaković, Jana; Batalović, Katarina

(2021)

TY  - JOUR
AU  - Dragojlović, Milijana
AU  - Milanović, Igor
AU  - Gradišek, Anton
AU  - Kurko, Sandra V.
AU  - Mitrić, Miodrag
AU  - Umićević, Ana
AU  - Radaković, Jana
AU  - Batalović, Katarina
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9091
AB  - LiAlH4 is a promising material for hydrogen storage, having the theoretical gravimetric density of 10.6 wt% H2. In order to decrease the temperature where hydrogen is released, we investigated the catalytic influence of Fe2O3 on LiAlH4 dehydrogenation, as a model case for understanding the effects transition oxide additives have in the catalysis process. Quick mechanochemical synthesis of LiAlH4 + 5 wt% Fe2O3 led to the significant decrease of the hydrogen desorption temperature, and desorption of over 7 wt%H2 in the temperature range 143–154 °C. Density functional theory (DFT)-based calculations with Tran-Blaha modified Becke-Johnson functional (TBmBJ) address the electronic structure of LiAlH4 and Li3AlH6. 57Fe Mössbauer study shows the change in the oxidational state of iron during hydrogen desorption, while the 1H NMR study reveals the presence of paramagnetic species that affect relaxation. The electron transfer from hydrides is discussed as the proposed mechanism of destabilization of LiAlH4 + 5 wt% Fe2O3. © 2021 Hydrogen Energy Publications LLC
T2  - International Journal of Hydrogen Energy
T1  - Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study
VL  - 46
IS  - 24
SP  - 13070
EP  - 13081
DO  - 10.1016/j.ijhydene.2021.01.086
ER  - 
@article{
author = "Dragojlović, Milijana and Milanović, Igor and Gradišek, Anton and Kurko, Sandra V. and Mitrić, Miodrag and Umićević, Ana and Radaković, Jana and Batalović, Katarina",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9091",
abstract = "LiAlH4 is a promising material for hydrogen storage, having the theoretical gravimetric density of 10.6 wt% H2. In order to decrease the temperature where hydrogen is released, we investigated the catalytic influence of Fe2O3 on LiAlH4 dehydrogenation, as a model case for understanding the effects transition oxide additives have in the catalysis process. Quick mechanochemical synthesis of LiAlH4 + 5 wt% Fe2O3 led to the significant decrease of the hydrogen desorption temperature, and desorption of over 7 wt%H2 in the temperature range 143–154 °C. Density functional theory (DFT)-based calculations with Tran-Blaha modified Becke-Johnson functional (TBmBJ) address the electronic structure of LiAlH4 and Li3AlH6. 57Fe Mössbauer study shows the change in the oxidational state of iron during hydrogen desorption, while the 1H NMR study reveals the presence of paramagnetic species that affect relaxation. The electron transfer from hydrides is discussed as the proposed mechanism of destabilization of LiAlH4 + 5 wt% Fe2O3. © 2021 Hydrogen Energy Publications LLC",
journal = "International Journal of Hydrogen Energy",
title = "Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study",
volume = "46",
number = "24",
pages = "13070-13081",
doi = "10.1016/j.ijhydene.2021.01.086"
}
Dragojlović, M., Milanović, I., Gradišek, A., Kurko, S. V., Mitrić, M., Umićević, A., Radaković, J.,& Batalović, K. (2021). Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study.
International Journal of Hydrogen Energy, 46(24), 13070-13081.
https://doi.org/10.1016/j.ijhydene.2021.01.086
Dragojlović M, Milanović I, Gradišek A, Kurko SV, Mitrić M, Umićević A, Radaković J, Batalović K. Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study. International Journal of Hydrogen Energy. 2021;46(24):13070-13081
Dragojlović Milijana, Milanović Igor, Gradišek Anton, Kurko Sandra V., Mitrić Miodrag, Umićević Ana, Radaković Jana, Batalović Katarina, "Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study" International Journal of Hydrogen Energy, 46, no. 24 (2021):13070-13081,
https://doi.org/10.1016/j.ijhydene.2021.01.086 .

Study of MW-scale biogas-fed SOFC-WGS-TSA-PEMFC hybrid power technology as distributed energy system: Thermodynamic, exergetic and thermo-economic evaluation

Wu, Zhen; Yao, Jing; Zhu, Pengfei; Yang, Fusheng; Meng, Xiangyu; Kurko, Sandra V.; Zhang, Zaoxiao

(2021)

TY  - JOUR
AU  - Wu, Zhen
AU  - Yao, Jing
AU  - Zhu, Pengfei
AU  - Yang, Fusheng
AU  - Meng, Xiangyu
AU  - Kurko, Sandra V.
AU  - Zhang, Zaoxiao
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9074
AB  - Advanced biogas power generation technology has been attracting attentions, which contributes to the waste disposal and the mitigation of greenhouse gas emissions. This work proposes and models a novel biogas-fed hybrid power generation system consisting of solid oxide fuel cell, water gas shift reaction, thermal swing adsorption and proton exchange membrane fuel cell (SOFC-WGS-TSA-PEMFC). The thermodynamic, exergetic, and thermo-economic analyses of this hybrid system for power generation were conducted to comprehensively evaluate its performance. It was found that the novel biogas-fed hybrid system has a gross energy conversion efficiency of 68.63% and exergy efficiency of 65.36%, indicating high efficiency for this kind of hybrid power technology. The market sensitivity analysis showed that the hybrid system also has a low sensitivity to market price fluctuation. Under the current subsidy level for the distributed biogas power plant, the levelized cost of energy can be lowered to 0.02942 $/kWh for a 1 MW scale system. Accordingly, the payback period and annual return on investment can reach 1.4 year and about 20%, respectively. These results reveal that the proposed hybrid system is promising and economically feasible as a distributed power plant, especially for the small power scale (no more than 2 MW).
T2  - International Journal of Hydrogen Energy
T1  - Study of MW-scale biogas-fed SOFC-WGS-TSA-PEMFC hybrid power technology as distributed energy system: Thermodynamic, exergetic and thermo-economic evaluation
VL  - 46
IS  - 19
SP  - 11183
EP  - 11198
DO  - 10.1016/j.ijhydene.2020.02.111
ER  - 
@article{
author = "Wu, Zhen and Yao, Jing and Zhu, Pengfei and Yang, Fusheng and Meng, Xiangyu and Kurko, Sandra V. and Zhang, Zaoxiao",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9074",
abstract = "Advanced biogas power generation technology has been attracting attentions, which contributes to the waste disposal and the mitigation of greenhouse gas emissions. This work proposes and models a novel biogas-fed hybrid power generation system consisting of solid oxide fuel cell, water gas shift reaction, thermal swing adsorption and proton exchange membrane fuel cell (SOFC-WGS-TSA-PEMFC). The thermodynamic, exergetic, and thermo-economic analyses of this hybrid system for power generation were conducted to comprehensively evaluate its performance. It was found that the novel biogas-fed hybrid system has a gross energy conversion efficiency of 68.63% and exergy efficiency of 65.36%, indicating high efficiency for this kind of hybrid power technology. The market sensitivity analysis showed that the hybrid system also has a low sensitivity to market price fluctuation. Under the current subsidy level for the distributed biogas power plant, the levelized cost of energy can be lowered to 0.02942 $/kWh for a 1 MW scale system. Accordingly, the payback period and annual return on investment can reach 1.4 year and about 20%, respectively. These results reveal that the proposed hybrid system is promising and economically feasible as a distributed power plant, especially for the small power scale (no more than 2 MW).",
journal = "International Journal of Hydrogen Energy",
title = "Study of MW-scale biogas-fed SOFC-WGS-TSA-PEMFC hybrid power technology as distributed energy system: Thermodynamic, exergetic and thermo-economic evaluation",
volume = "46",
number = "19",
pages = "11183-11198",
doi = "10.1016/j.ijhydene.2020.02.111"
}
Wu, Z., Yao, J., Zhu, P., Yang, F., Meng, X., Kurko, S. V.,& Zhang, Z. (2021). Study of MW-scale biogas-fed SOFC-WGS-TSA-PEMFC hybrid power technology as distributed energy system: Thermodynamic, exergetic and thermo-economic evaluation.
International Journal of Hydrogen Energy, 46(19), 11183-11198.
https://doi.org/10.1016/j.ijhydene.2020.02.111
Wu Z, Yao J, Zhu P, Yang F, Meng X, Kurko SV, Zhang Z. Study of MW-scale biogas-fed SOFC-WGS-TSA-PEMFC hybrid power technology as distributed energy system: Thermodynamic, exergetic and thermo-economic evaluation. International Journal of Hydrogen Energy. 2021;46(19):11183-11198
Wu Zhen, Yao Jing, Zhu Pengfei, Yang Fusheng, Meng Xiangyu, Kurko Sandra V., Zhang Zaoxiao, "Study of MW-scale biogas-fed SOFC-WGS-TSA-PEMFC hybrid power technology as distributed energy system: Thermodynamic, exergetic and thermo-economic evaluation" International Journal of Hydrogen Energy, 46, no. 19 (2021):11183-11198,
https://doi.org/10.1016/j.ijhydene.2020.02.111 .
3
3

Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study

Dragojlović, Milijana; Milanović, Igor; Gradišek, Anton; Kurko, Sandra; Mitrić, Miodrag; Umićević, Ana; Radaković, Jana; Batalović, Katarina

(2021)

TY  - JOUR
AU  - Dragojlović, Milijana
AU  - Milanović, Igor
AU  - Gradišek, Anton
AU  - Kurko, Sandra
AU  - Mitrić, Miodrag
AU  - Umićević, Ana
AU  - Radaković, Jana
AU  - Batalović, Katarina
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9087
AB  - LiAlH4 is a promising material for hydrogen storage, having the theoretical gravimetric density of 10.6 wt% H2. In order to decrease the temperature where hydrogen is released, we investigated the catalytic influence of Fe2O3 on LiAlH4 dehydrogenation, as a model case for understanding the effects transition oxide additives have in the catalysis process. Quick mechanochemical synthesis of LiAlH4 + 5 wt% Fe2O3 led to the significant decrease of the hydrogen desorption temperature, and desorption of over 7 wt%H2 in the temperature range 143–154 °C. Density functional theory (DFT)-based calculations with Tran-Blaha modified Becke-Johnson functional (TBmBJ) address the electronic structure of LiAlH4 and Li3AlH6. 57Fe Mössbauer study shows the change in the oxidational state of iron during hydrogen desorption, while the 1H NMR study reveals the presence of paramagnetic species that affect relaxation. The electron transfer from hydrides is discussed as the proposed mechanism of destabilization of LiAlH4 + 5 wt% Fe2O3. © 2021 Hydrogen Energy Publications LLC
T2  - International Journal of Hydrogen Energy
T1  - Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study
VL  - 46
IS  - 24
SP  - 13070
EP  - 13081
DO  - 10.1016/j.ijhydene.2021.01.086
ER  - 
@article{
author = "Dragojlović, Milijana and Milanović, Igor and Gradišek, Anton and Kurko, Sandra and Mitrić, Miodrag and Umićević, Ana and Radaković, Jana and Batalović, Katarina",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9087",
abstract = "LiAlH4 is a promising material for hydrogen storage, having the theoretical gravimetric density of 10.6 wt% H2. In order to decrease the temperature where hydrogen is released, we investigated the catalytic influence of Fe2O3 on LiAlH4 dehydrogenation, as a model case for understanding the effects transition oxide additives have in the catalysis process. Quick mechanochemical synthesis of LiAlH4 + 5 wt% Fe2O3 led to the significant decrease of the hydrogen desorption temperature, and desorption of over 7 wt%H2 in the temperature range 143–154 °C. Density functional theory (DFT)-based calculations with Tran-Blaha modified Becke-Johnson functional (TBmBJ) address the electronic structure of LiAlH4 and Li3AlH6. 57Fe Mössbauer study shows the change in the oxidational state of iron during hydrogen desorption, while the 1H NMR study reveals the presence of paramagnetic species that affect relaxation. The electron transfer from hydrides is discussed as the proposed mechanism of destabilization of LiAlH4 + 5 wt% Fe2O3. © 2021 Hydrogen Energy Publications LLC",
journal = "International Journal of Hydrogen Energy",
title = "Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study",
volume = "46",
number = "24",
pages = "13070-13081",
doi = "10.1016/j.ijhydene.2021.01.086"
}
Dragojlović, M., Milanović, I., Gradišek, A., Kurko, S., Mitrić, M., Umićević, A., Radaković, J.,& Batalović, K. (2021). Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study.
International Journal of Hydrogen Energy, 46(24), 13070-13081.
https://doi.org/10.1016/j.ijhydene.2021.01.086
Dragojlović M, Milanović I, Gradišek A, Kurko S, Mitrić M, Umićević A, Radaković J, Batalović K. Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study. International Journal of Hydrogen Energy. 2021;46(24):13070-13081
Dragojlović Milijana, Milanović Igor, Gradišek Anton, Kurko Sandra, Mitrić Miodrag, Umićević Ana, Radaković Jana, Batalović Katarina, "Mechanochemical modification of LiAlH4 with Fe2O3 - A combined DFT and experimental study" International Journal of Hydrogen Energy, 46, no. 24 (2021):13070-13081,
https://doi.org/10.1016/j.ijhydene.2021.01.086 .

The Effect of Water Concentration in Ethyl Alcohol on the Environmentally Assisted Embrittlement of Austempered Ductile Irons

Janjatović, Petar; Erić-Cekić, Olivera; Siđanin, Leposava; Balos, Sebastian; Dramićanin, Miroslav; Grbović-Novaković, Jasmina; Rajnović, Dragan

(2021)

TY  - JOUR
AU  - Janjatović, Petar
AU  - Erić-Cekić, Olivera
AU  - Siđanin, Leposava
AU  - Balos, Sebastian
AU  - Dramićanin, Miroslav
AU  - Grbović-Novaković, Jasmina
AU  - Rajnović, Dragan
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9179
AB  - Austempered ductile iron (ADI) is an advanced cast iron material that has a broad field of application and, among others, it is used in contact and for conveyance of fluids. However, it is noticed that in contact with some fluids, especially water, ADI material becomes brittle. The most significant decrease is established for the elongation. However, the influence of water and the cause of this phenomenon is still not fully understood. For that reason, in this paper, the influence of different water concentrations in ethyl alcohol on the mechanical properties of ADI materials was studied. The test was performed on two different types of ADI materials in 0.2, 4, 10, and 100 vol.% water concentration environments, and in dry condition. It was found that even the smallest concentration of water (0.2 vol.%) causes formation of the embrittled zone at fracture surface. However, not all mechanical properties were affected equally and not all water concentrations have been critical. The highest deterioration was established in the elongation, followed by the ultimate tensile strength, while the proof strength was affected least.
T2  - Metals
T1  - The Effect of Water Concentration in Ethyl Alcohol on the Environmentally Assisted Embrittlement of Austempered Ductile Irons
VL  - 11
IS  - 1
SP  - 94
DO  - 10.3390/met11010094
ER  - 
@article{
author = "Janjatović, Petar and Erić-Cekić, Olivera and Siđanin, Leposava and Balos, Sebastian and Dramićanin, Miroslav and Grbović-Novaković, Jasmina and Rajnović, Dragan",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9179",
abstract = "Austempered ductile iron (ADI) is an advanced cast iron material that has a broad field of application and, among others, it is used in contact and for conveyance of fluids. However, it is noticed that in contact with some fluids, especially water, ADI material becomes brittle. The most significant decrease is established for the elongation. However, the influence of water and the cause of this phenomenon is still not fully understood. For that reason, in this paper, the influence of different water concentrations in ethyl alcohol on the mechanical properties of ADI materials was studied. The test was performed on two different types of ADI materials in 0.2, 4, 10, and 100 vol.% water concentration environments, and in dry condition. It was found that even the smallest concentration of water (0.2 vol.%) causes formation of the embrittled zone at fracture surface. However, not all mechanical properties were affected equally and not all water concentrations have been critical. The highest deterioration was established in the elongation, followed by the ultimate tensile strength, while the proof strength was affected least.",
journal = "Metals",
title = "The Effect of Water Concentration in Ethyl Alcohol on the Environmentally Assisted Embrittlement of Austempered Ductile Irons",
volume = "11",
number = "1",
pages = "94",
doi = "10.3390/met11010094"
}
Janjatović, P., Erić-Cekić, O., Siđanin, L., Balos, S., Dramićanin, M., Grbović-Novaković, J.,& Rajnović, D. (2021). The Effect of Water Concentration in Ethyl Alcohol on the Environmentally Assisted Embrittlement of Austempered Ductile Irons.
Metals, 11(1), 94.
https://doi.org/10.3390/met11010094
Janjatović P, Erić-Cekić O, Siđanin L, Balos S, Dramićanin M, Grbović-Novaković J, Rajnović D. The Effect of Water Concentration in Ethyl Alcohol on the Environmentally Assisted Embrittlement of Austempered Ductile Irons. Metals. 2021;11(1):94
Janjatović Petar, Erić-Cekić Olivera, Siđanin Leposava, Balos Sebastian, Dramićanin Miroslav, Grbović-Novaković Jasmina, Rajnović Dragan, "The Effect of Water Concentration in Ethyl Alcohol on the Environmentally Assisted Embrittlement of Austempered Ductile Irons" Metals, 11, no. 1 (2021):94,
https://doi.org/10.3390/met11010094 .
2
1
2

Life Cycle Energy Assessment of biohydrogen production via biogas steam reforming: Case study of biogas plant on a farm in Serbia

Cvetković, Slobodan M.; Kaluđerović-Radoičić, Tatjana; Kijevčanin, Mirjana; Grbović-Novaković, Jasmina

(2021)

TY  - JOUR
AU  - Cvetković, Slobodan M.
AU  - Kaluđerović-Radoičić, Tatjana
AU  - Kijevčanin, Mirjana
AU  - Grbović-Novaković, Jasmina
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9128
AB  - The aim of this paper is to demonstrate and to quantify energy flows in a life cycle of biogas to biohydrogen production, starting from feedstock materials via anaerobic digestion, biogas upgrading, biohydrogen production, to the end of biogas system (application of digestate as fertilizer in agriculture). The performance of the biogas plant of Mirotin dairy farm in Serbia has been assessed. According to Life Cycle Energy Assessment approach, results obtained in this study have shown that biohydrogen production via biogas steam reforming has negative energy balance (with −16,837 GJ). It has also been demonstrated that this process is energy unsustainable in an environmental context. In future analysis it would be necessary to consider the other aspects of sustainability, e.g. the economical and social factors in order to estimate the overall sustainability of the biogas utilization pathways, especially having in mind that the technology of converting biogas to hydrogen is still in the development phase. © 2021 Hydrogen Energy Publications LLC
T2  - International Journal of Hydrogen Energy
T1  - Life Cycle Energy Assessment of biohydrogen production via biogas steam reforming: Case study of biogas plant on a farm in Serbia
VL  - 46
IS  - 27
SP  - 14130
EP  - 14137
DO  - 10.1016/j.ijhydene.2021.01.181
ER  - 
@article{
author = "Cvetković, Slobodan M. and Kaluđerović-Radoičić, Tatjana and Kijevčanin, Mirjana and Grbović-Novaković, Jasmina",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9128",
abstract = "The aim of this paper is to demonstrate and to quantify energy flows in a life cycle of biogas to biohydrogen production, starting from feedstock materials via anaerobic digestion, biogas upgrading, biohydrogen production, to the end of biogas system (application of digestate as fertilizer in agriculture). The performance of the biogas plant of Mirotin dairy farm in Serbia has been assessed. According to Life Cycle Energy Assessment approach, results obtained in this study have shown that biohydrogen production via biogas steam reforming has negative energy balance (with −16,837 GJ). It has also been demonstrated that this process is energy unsustainable in an environmental context. In future analysis it would be necessary to consider the other aspects of sustainability, e.g. the economical and social factors in order to estimate the overall sustainability of the biogas utilization pathways, especially having in mind that the technology of converting biogas to hydrogen is still in the development phase. © 2021 Hydrogen Energy Publications LLC",
journal = "International Journal of Hydrogen Energy",
title = "Life Cycle Energy Assessment of biohydrogen production via biogas steam reforming: Case study of biogas plant on a farm in Serbia",
volume = "46",
number = "27",
pages = "14130-14137",
doi = "10.1016/j.ijhydene.2021.01.181"
}
Cvetković, S. M., Kaluđerović-Radoičić, T., Kijevčanin, M.,& Grbović-Novaković, J. (2021). Life Cycle Energy Assessment of biohydrogen production via biogas steam reforming: Case study of biogas plant on a farm in Serbia.
International Journal of Hydrogen Energy, 46(27), 14130-14137.
https://doi.org/10.1016/j.ijhydene.2021.01.181
Cvetković SM, Kaluđerović-Radoičić T, Kijevčanin M, Grbović-Novaković J. Life Cycle Energy Assessment of biohydrogen production via biogas steam reforming: Case study of biogas plant on a farm in Serbia. International Journal of Hydrogen Energy. 2021;46(27):14130-14137
Cvetković Slobodan M., Kaluđerović-Radoičić Tatjana, Kijevčanin Mirjana, Grbović-Novaković Jasmina, "Life Cycle Energy Assessment of biohydrogen production via biogas steam reforming: Case study of biogas plant on a farm in Serbia" International Journal of Hydrogen Energy, 46, no. 27 (2021):14130-14137,
https://doi.org/10.1016/j.ijhydene.2021.01.181 .

Bioevaluation of glucose-modified liposomes as a potential drug delivery system for cancer treatment using 177-Lu radiotracking

Cvjetinović, Đorđe; Prijović, Željko; Janković, Drina; Radović, Magdalena; Mirković, Marija D.; Milanović, Zorana; Mojović, Miloš; Škalamera, Đani; Vranješ-Đurić, Sanja

(2021)

TY  - JOUR
AU  - Cvjetinović, Đorđe
AU  - Prijović, Željko
AU  - Janković, Drina
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Milanović, Zorana
AU  - Mojović, Miloš
AU  - Škalamera, Đani
AU  - Vranješ-Đurić, Sanja
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9151
AB  - Liposomes are promising drug's delivery systems due to decreased toxicity of the liposome-encapsulated drug, but wider clinical application requires their more efficient tumor targeting with uptake, controlled drug release and higher shelf life. The unique metabolic characteristics of cancer cells based on higher demand for energy and therefore increased glucose utilization were exploited in the design of glucose modified liposomes (GML) with the aim to provide increased tumor targeting via glucose transporters and increased ability of drug delivery into tumor cells. Tumor accumulating potential of GML and non-glucose liposomes (NGL) were investigated on CT26 and LS174T tumor-bearing mice by simple and reliable radiotracer method using 177Lu as radioactive marker. Both liposomes, GML and NGL were radiolabeled in high radiolabeling yield, showing high in vitro stability in biological media, as the main prerequisite for the biodistribution studies. Tumors displayed significantly better accumulation of 177Lu-GML with the maximum uptake 6 h post-injection (5.8 ± 0.2%/g in LS174T tumor and 5.1 ± 0.5%/g in CT26 tumor), compared to negligible uptake of 177Lu-NGL (0.6 ± 0.1%/g in LS174T tumor and 0.9 ± 0.2%/g in CT26 tumor). Results of comparative biodistribution studies of 177Lu-NGL and 177Lu-GML indicate that increased accumulation of GML is enabled by glucose transporters and subsequent endocytosis, resulting in their prolonged retention in tumor tissues (up to 72 h). Direct radiolabeling of liposomes with 177Lu may be used not only for biodistribution studies using radiotracking, but also for cancer treatment. © 2021 Elsevier B.V.
T2  - Journal of Controlled Release
T1  - Bioevaluation of glucose-modified liposomes as a potential drug delivery system for cancer treatment using 177-Lu radiotracking
VL  - 332
SP  - 301
EP  - 311
DO  - 10.1016/j.jconrel.2021.03.006
ER  - 
@article{
author = "Cvjetinović, Đorđe and Prijović, Željko and Janković, Drina and Radović, Magdalena and Mirković, Marija D. and Milanović, Zorana and Mojović, Miloš and Škalamera, Đani and Vranješ-Đurić, Sanja",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9151",
abstract = "Liposomes are promising drug's delivery systems due to decreased toxicity of the liposome-encapsulated drug, but wider clinical application requires their more efficient tumor targeting with uptake, controlled drug release and higher shelf life. The unique metabolic characteristics of cancer cells based on higher demand for energy and therefore increased glucose utilization were exploited in the design of glucose modified liposomes (GML) with the aim to provide increased tumor targeting via glucose transporters and increased ability of drug delivery into tumor cells. Tumor accumulating potential of GML and non-glucose liposomes (NGL) were investigated on CT26 and LS174T tumor-bearing mice by simple and reliable radiotracer method using 177Lu as radioactive marker. Both liposomes, GML and NGL were radiolabeled in high radiolabeling yield, showing high in vitro stability in biological media, as the main prerequisite for the biodistribution studies. Tumors displayed significantly better accumulation of 177Lu-GML with the maximum uptake 6 h post-injection (5.8 ± 0.2%/g in LS174T tumor and 5.1 ± 0.5%/g in CT26 tumor), compared to negligible uptake of 177Lu-NGL (0.6 ± 0.1%/g in LS174T tumor and 0.9 ± 0.2%/g in CT26 tumor). Results of comparative biodistribution studies of 177Lu-NGL and 177Lu-GML indicate that increased accumulation of GML is enabled by glucose transporters and subsequent endocytosis, resulting in their prolonged retention in tumor tissues (up to 72 h). Direct radiolabeling of liposomes with 177Lu may be used not only for biodistribution studies using radiotracking, but also for cancer treatment. © 2021 Elsevier B.V.",
journal = "Journal of Controlled Release",
title = "Bioevaluation of glucose-modified liposomes as a potential drug delivery system for cancer treatment using 177-Lu radiotracking",
volume = "332",
pages = "301-311",
doi = "10.1016/j.jconrel.2021.03.006"
}
Cvjetinović, Đ., Prijović, Ž., Janković, D., Radović, M., Mirković, M. D., Milanović, Z., Mojović, M., Škalamera, Đ.,& Vranješ-Đurić, S. (2021). Bioevaluation of glucose-modified liposomes as a potential drug delivery system for cancer treatment using 177-Lu radiotracking.
Journal of Controlled Release, 332, 301-311.
https://doi.org/10.1016/j.jconrel.2021.03.006
Cvjetinović Đ, Prijović Ž, Janković D, Radović M, Mirković MD, Milanović Z, Mojović M, Škalamera Đ, Vranješ-Đurić S. Bioevaluation of glucose-modified liposomes as a potential drug delivery system for cancer treatment using 177-Lu radiotracking. Journal of Controlled Release. 2021;332:301-311
Cvjetinović Đorđe, Prijović Željko, Janković Drina, Radović Magdalena, Mirković Marija D., Milanović Zorana, Mojović Miloš, Škalamera Đani, Vranješ-Đurić Sanja, "Bioevaluation of glucose-modified liposomes as a potential drug delivery system for cancer treatment using 177-Lu radiotracking" Journal of Controlled Release, 332 (2021):301-311,
https://doi.org/10.1016/j.jconrel.2021.03.006 .
1

Synthesis, structure, magnetic properties and DFT study of a dinuclear copper(II) macrocyclic complex containing acetate groups

Abedi, Marjan; Butcher, Ray J.; Nasser Shamkhali, Amir; Spasojević, Vojislav; Al-Ameed, Karrar; Abedi, Parissa

(2021)

TY  - JOUR
AU  - Abedi, Marjan
AU  - Butcher, Ray J.
AU  - Nasser Shamkhali, Amir
AU  - Spasojević, Vojislav
AU  - Al-Ameed, Karrar
AU  - Abedi, Parissa
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9137
AB  - Synthesis, spectroscopic characterizations and single crystal X-ray structure of a new dinuclear Copper(II) complex of the form [Cu2L(µ-O-OAc)(OAc)2](PF6) are reported. The molecular structure of the complex indicates that acetate ions coordinate to metals in different types, as a unidentate ligand, as a chelating ligand and in arrangement involving chelation and bridging. The metal centers in this complex are five coordinated with two different geometries (trigonal bipyramid and square pyramidal). Magnetic measurements show the presence of a strong Cu–Cu antiferromagnetic interaction. Moreover, density functional theory (DFT) calculations were performed to deeper analysis of the structure and vibrational properties of the synthesized complex. An interesting result is failure of DFT and second order Møller-Plesset perturbation (MP2) methods for prediction of antiferromagnetic coupling in the synthesized complex which introduces its as a new challenging material for future computational chemistry investigations. © 2021 Elsevier B.V.
T2  - Inorganica Chimica Acta
T1  - Synthesis, structure, magnetic properties and DFT study of a dinuclear copper(II) macrocyclic complex containing acetate groups
VL  - 520
SP  - 120310
DO  - 10.1016/j.ica.2021.120310
ER  - 
@article{
author = "Abedi, Marjan and Butcher, Ray J. and Nasser Shamkhali, Amir and Spasojević, Vojislav and Al-Ameed, Karrar and Abedi, Parissa",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9137",
abstract = "Synthesis, spectroscopic characterizations and single crystal X-ray structure of a new dinuclear Copper(II) complex of the form [Cu2L(µ-O-OAc)(OAc)2](PF6) are reported. The molecular structure of the complex indicates that acetate ions coordinate to metals in different types, as a unidentate ligand, as a chelating ligand and in arrangement involving chelation and bridging. The metal centers in this complex are five coordinated with two different geometries (trigonal bipyramid and square pyramidal). Magnetic measurements show the presence of a strong Cu–Cu antiferromagnetic interaction. Moreover, density functional theory (DFT) calculations were performed to deeper analysis of the structure and vibrational properties of the synthesized complex. An interesting result is failure of DFT and second order Møller-Plesset perturbation (MP2) methods for prediction of antiferromagnetic coupling in the synthesized complex which introduces its as a new challenging material for future computational chemistry investigations. © 2021 Elsevier B.V.",
journal = "Inorganica Chimica Acta",
title = "Synthesis, structure, magnetic properties and DFT study of a dinuclear copper(II) macrocyclic complex containing acetate groups",
volume = "520",
pages = "120310",
doi = "10.1016/j.ica.2021.120310"
}
Abedi, M., Butcher, R. J., Nasser Shamkhali, A., Spasojević, V., Al-Ameed, K.,& Abedi, P. (2021). Synthesis, structure, magnetic properties and DFT study of a dinuclear copper(II) macrocyclic complex containing acetate groups.
Inorganica Chimica Acta, 520, 120310.
https://doi.org/10.1016/j.ica.2021.120310
Abedi M, Butcher RJ, Nasser Shamkhali A, Spasojević V, Al-Ameed K, Abedi P. Synthesis, structure, magnetic properties and DFT study of a dinuclear copper(II) macrocyclic complex containing acetate groups. Inorganica Chimica Acta. 2021;520:120310
Abedi Marjan, Butcher Ray J., Nasser Shamkhali Amir, Spasojević Vojislav, Al-Ameed Karrar, Abedi Parissa, "Synthesis, structure, magnetic properties and DFT study of a dinuclear copper(II) macrocyclic complex containing acetate groups" Inorganica Chimica Acta, 520 (2021):120310,
https://doi.org/10.1016/j.ica.2021.120310 .

Electrochemical and structural study on cycling performance of γ-LiV2O5 cathode

Milović, Miloš; Vujković, Milica; Jugović, Dragana; Mitrić, Miodrag

(2021)

TY  - JOUR
AU  - Milović, Miloš
AU  - Vujković, Milica
AU  - Jugović, Dragana
AU  - Mitrić, Miodrag
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9148
AB  - Electrochemical and structural properties of LiV2O5 cathode were investigated. Obtained by solid state reaction at high temperature the material crystallized as gamma polymorph phase, γ-LiV2O5. The gamma structure provides two crystallographic sites to accommodate lithium ions, Li1 and Li2 position. Lithium insertion at these two sites occurs at two respective voltages versus lithium metal: ~3.6 V (Li1) and ~2.4 V (Li2). Intercalation at Li1 position is reversible in both organic and aqueous electrolyte and provides stable cycling performance at the high voltage. On the contrary, sluggish insertion/removal of Li+ at Li2 sites causes unstable performance and significant storage capacity fade at lower voltages. Lithium diffusion 3d landscape was determined by bond valence calculations applied on the γ-LiV2O5 phase, as well as on the metastable phases of γ′-V2O5 and ζ-Li2V2O5 that exist at high and low voltages respectively. The model was proposed based on inactivity of Li2 position of the metastable ζ-Li2V2O5 phase which provides explanation for the observed storage capacity loss at low voltages. © 2021 Elsevier Ltd and Techna Group S.r.l.
T2  - Ceramics International
T1  - Electrochemical and structural study on cycling performance of γ-LiV2O5 cathode
VL  - 47
IS  - 12
SP  - 17077
EP  - 17083
DO  - 10.1016/j.ceramint.2021.03.016
ER  - 
@article{
author = "Milović, Miloš and Vujković, Milica and Jugović, Dragana and Mitrić, Miodrag",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9148",
abstract = "Electrochemical and structural properties of LiV2O5 cathode were investigated. Obtained by solid state reaction at high temperature the material crystallized as gamma polymorph phase, γ-LiV2O5. The gamma structure provides two crystallographic sites to accommodate lithium ions, Li1 and Li2 position. Lithium insertion at these two sites occurs at two respective voltages versus lithium metal: ~3.6 V (Li1) and ~2.4 V (Li2). Intercalation at Li1 position is reversible in both organic and aqueous electrolyte and provides stable cycling performance at the high voltage. On the contrary, sluggish insertion/removal of Li+ at Li2 sites causes unstable performance and significant storage capacity fade at lower voltages. Lithium diffusion 3d landscape was determined by bond valence calculations applied on the γ-LiV2O5 phase, as well as on the metastable phases of γ′-V2O5 and ζ-Li2V2O5 that exist at high and low voltages respectively. The model was proposed based on inactivity of Li2 position of the metastable ζ-Li2V2O5 phase which provides explanation for the observed storage capacity loss at low voltages. © 2021 Elsevier Ltd and Techna Group S.r.l.",
journal = "Ceramics International",
title = "Electrochemical and structural study on cycling performance of γ-LiV2O5 cathode",
volume = "47",
number = "12",
pages = "17077-17083",
doi = "10.1016/j.ceramint.2021.03.016"
}
Milović, M., Vujković, M., Jugović, D.,& Mitrić, M. (2021). Electrochemical and structural study on cycling performance of γ-LiV2O5 cathode.
Ceramics International, 47(12), 17077-17083.
https://doi.org/10.1016/j.ceramint.2021.03.016
Milović M, Vujković M, Jugović D, Mitrić M. Electrochemical and structural study on cycling performance of γ-LiV2O5 cathode. Ceramics International. 2021;47(12):17077-17083
Milović Miloš, Vujković Milica, Jugović Dragana, Mitrić Miodrag, "Electrochemical and structural study on cycling performance of γ-LiV2O5 cathode" Ceramics International, 47, no. 12 (2021):17077-17083,
https://doi.org/10.1016/j.ceramint.2021.03.016 .

Radon-222: environmental behavior and impact to (human and non-human) biota

Ćujić, Mirjana; Janković-Mandić, Ljiljana; Petrović, Jelena M.; Dragović, Ranko M.; Đorđević, Milan; Đokić, Mrđan; Dragović, Snežana D.

(2021)

TY  - JOUR
AU  - Ćujić, Mirjana
AU  - Janković-Mandić, Ljiljana
AU  - Petrović, Jelena M.
AU  - Dragović, Ranko M.
AU  - Đorđević, Milan
AU  - Đokić, Mrđan
AU  - Dragović, Snežana D.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8903
AB  - As an inert radioactive gas, 222Rn could be easily transported to the atmosphere via emanation, migration, or exhalation. Research measurements pointed out that 222Rn activity concentration changes during the winter and summer months, as well as during wet and dry season periods. Changes in radon concentration can affect the atmospheric electric field. At the boundary layer near the ground, short-lived daughters of 222Rn can be used as natural tracers in the atmosphere. In this work, factors controlling 222Rn pathways in the environment and its levels in soil gas and outdoor air are summarized. 222Rn has a short half-life of 3.82 days, but the dose rate due to radon and its radioactive progeny could be significant to the living beings. Epidemiological studies on humans pointed out that up to 14% of lung cancers are induced by exposure to low and moderate concentrations of radon. Animals that breed in ground holes have been exposed to the higher doses due to radiation present in soil air. During the years, different dose-effect models are developed for risk assessment on human and non-human biota. In this work are reviewed research results of 222Rn exposure of human and non-human biota. © 2020, ISB.
T2  - International Journal of Biometeorology
T1  - Radon-222: environmental behavior and impact to (human and non-human) biota
VL  - 65
IS  - 1
SP  - 69
EP  - 83
DO  - 10.1007/s00484-020-01860-w
ER  - 
@article{
author = "Ćujić, Mirjana and Janković-Mandić, Ljiljana and Petrović, Jelena M. and Dragović, Ranko M. and Đorđević, Milan and Đokić, Mrđan and Dragović, Snežana D.",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/8903",
abstract = "As an inert radioactive gas, 222Rn could be easily transported to the atmosphere via emanation, migration, or exhalation. Research measurements pointed out that 222Rn activity concentration changes during the winter and summer months, as well as during wet and dry season periods. Changes in radon concentration can affect the atmospheric electric field. At the boundary layer near the ground, short-lived daughters of 222Rn can be used as natural tracers in the atmosphere. In this work, factors controlling 222Rn pathways in the environment and its levels in soil gas and outdoor air are summarized. 222Rn has a short half-life of 3.82 days, but the dose rate due to radon and its radioactive progeny could be significant to the living beings. Epidemiological studies on humans pointed out that up to 14% of lung cancers are induced by exposure to low and moderate concentrations of radon. Animals that breed in ground holes have been exposed to the higher doses due to radiation present in soil air. During the years, different dose-effect models are developed for risk assessment on human and non-human biota. In this work are reviewed research results of 222Rn exposure of human and non-human biota. © 2020, ISB.",
journal = "International Journal of Biometeorology",
title = "Radon-222: environmental behavior and impact to (human and non-human) biota",
volume = "65",
number = "1",
pages = "69-83",
doi = "10.1007/s00484-020-01860-w"
}
Ćujić, M., Janković-Mandić, L., Petrović, J. M., Dragović, R. M., Đorđević, M., Đokić, M.,& Dragović, S. D. (2021). Radon-222: environmental behavior and impact to (human and non-human) biota.
International Journal of Biometeorology, 65(1), 69-83.
https://doi.org/10.1007/s00484-020-01860-w
Ćujić M, Janković-Mandić L, Petrović JM, Dragović RM, Đorđević M, Đokić M, Dragović SD. Radon-222: environmental behavior and impact to (human and non-human) biota. International Journal of Biometeorology. 2021;65(1):69-83
Ćujić Mirjana, Janković-Mandić Ljiljana, Petrović Jelena M., Dragović Ranko M., Đorđević Milan, Đokić Mrđan, Dragović Snežana D., "Radon-222: environmental behavior and impact to (human and non-human) biota" International Journal of Biometeorology, 65, no. 1 (2021):69-83,
https://doi.org/10.1007/s00484-020-01860-w .
6
170
2

Nano-silica-based urea–formaldehyde composite with some derivates of coumarin as formaldehyde scavenger: hydrolytical and thermal stability

Jovanović, Vojislav; Samaržija-Jovanović, Suzana; Petković, Branka B.; Jovanović, Slaviša; Marković, Gordana; Porobić, Slavica; Marinović-Cincović, Milena

(2021)

TY  - JOUR
AU  - Jovanović, Vojislav
AU  - Samaržija-Jovanović, Suzana
AU  - Petković, Branka B.
AU  - Jovanović, Slaviša
AU  - Marković, Gordana
AU  - Porobić, Slavica
AU  - Marinović-Cincović, Milena
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8907
AB  - The hydrolytic stability of two nano-SiO2-based UF composites with derivates of coumarin (names as K-1 and K-2) was investigated. K-1 is 3-nitro-4-(p-tolylamino)-2H-chromen-2-one and K-2: 4-((3-nitro-2-oxo-2H-chromen-4-yl)amino)benzenesulfonamide. Two types of nano-silica-based urea–formaldehyde (UF), composite materials with a formaldehyde-to-urea (F/U) ratio of 0.8, were synthesized (UF/K-1/SiO2, and UF/K-2/SiO2). The hydrolytic stability of modified UF composite was determined by measuring the mass loss and liberated formaldehyde concentration of modified UF composite after acid hydrolysis. Obtained results showed that the hydrolytic stability of modified resins with derivates of coumarin was enhanced. The formaldehyde emission of modified UF/K-1/SiO2 composite is lower compared with UF/K-2/SiO2 composite. The thermal behavior of materials was studied by non-isothermal thermo-gravimetric analysis and differential thermal gravimetry supported by data from ATR-IR spectroscopy. The shift of temperature values for selected mass losses (T5%) to a high temperature indicates the increase in thermal stability of samples based on UF resin modified with K-2. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
T2  - Polymer Bulletin
T1  - Nano-silica-based urea–formaldehyde composite with some derivates of coumarin as formaldehyde scavenger: hydrolytical and thermal stability
VL  - 78
IS  - 1
SP  - 399
EP  - 413
DO  - 10.1007/s00289-020-03114-6
ER  - 
@article{
author = "Jovanović, Vojislav and Samaržija-Jovanović, Suzana and Petković, Branka B. and Jovanović, Slaviša and Marković, Gordana and Porobić, Slavica and Marinović-Cincović, Milena",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/8907",
abstract = "The hydrolytic stability of two nano-SiO2-based UF composites with derivates of coumarin (names as K-1 and K-2) was investigated. K-1 is 3-nitro-4-(p-tolylamino)-2H-chromen-2-one and K-2: 4-((3-nitro-2-oxo-2H-chromen-4-yl)amino)benzenesulfonamide. Two types of nano-silica-based urea–formaldehyde (UF), composite materials with a formaldehyde-to-urea (F/U) ratio of 0.8, were synthesized (UF/K-1/SiO2, and UF/K-2/SiO2). The hydrolytic stability of modified UF composite was determined by measuring the mass loss and liberated formaldehyde concentration of modified UF composite after acid hydrolysis. Obtained results showed that the hydrolytic stability of modified resins with derivates of coumarin was enhanced. The formaldehyde emission of modified UF/K-1/SiO2 composite is lower compared with UF/K-2/SiO2 composite. The thermal behavior of materials was studied by non-isothermal thermo-gravimetric analysis and differential thermal gravimetry supported by data from ATR-IR spectroscopy. The shift of temperature values for selected mass losses (T5%) to a high temperature indicates the increase in thermal stability of samples based on UF resin modified with K-2. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.",
journal = "Polymer Bulletin",
title = "Nano-silica-based urea–formaldehyde composite with some derivates of coumarin as formaldehyde scavenger: hydrolytical and thermal stability",
volume = "78",
number = "1",
pages = "399-413",
doi = "10.1007/s00289-020-03114-6"
}
Jovanović, V., Samaržija-Jovanović, S., Petković, B. B., Jovanović, S., Marković, G., Porobić, S.,& Marinović-Cincović, M. (2021). Nano-silica-based urea–formaldehyde composite with some derivates of coumarin as formaldehyde scavenger: hydrolytical and thermal stability.
Polymer Bulletin, 78(1), 399-413.
https://doi.org/10.1007/s00289-020-03114-6
Jovanović V, Samaržija-Jovanović S, Petković BB, Jovanović S, Marković G, Porobić S, Marinović-Cincović M. Nano-silica-based urea–formaldehyde composite with some derivates of coumarin as formaldehyde scavenger: hydrolytical and thermal stability. Polymer Bulletin. 2021;78(1):399-413
Jovanović Vojislav, Samaržija-Jovanović Suzana, Petković Branka B., Jovanović Slaviša, Marković Gordana, Porobić Slavica, Marinović-Cincović Milena, "Nano-silica-based urea–formaldehyde composite with some derivates of coumarin as formaldehyde scavenger: hydrolytical and thermal stability" Polymer Bulletin, 78, no. 1 (2021):399-413,
https://doi.org/10.1007/s00289-020-03114-6 .

Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models

Matić, Ivana Z.; Ergün, Sercan; Đorđić Crnogorac, Marija; Misir, Sema; Aliyazicioğlu, Yüksel; Damjanović, Ana; Džudžević-Čančar, Hurija; Stanojković, Tatjana; Konanç, Kalbiye; Petrović, Nina

(2021)

TY  - JOUR
AU  - Matić, Ivana Z.
AU  - Ergün, Sercan
AU  - Đorđić Crnogorac, Marija
AU  - Misir, Sema
AU  - Aliyazicioğlu, Yüksel
AU  - Damjanović, Ana
AU  - Džudžević-Čančar, Hurija
AU  - Stanojković, Tatjana
AU  - Konanç, Kalbiye
AU  - Petrović, Nina
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9406
AB  - Six extracts were obtained from plant species Hypericum perforatum L., collected at Samsun in Turkey. The aim of this study was to examine the mechanisms of the anticancer activity of these extracts. Methanol, ethyl-acetate and hexane were used as a solvents for extraction from both branch-body part of the plant (extracts 1, 2 and 3) and from plant flowers (extracts 4, 5 and 6). The cytotoxic effects of the extracts were determined against 2D and 3D cancer cell models. Cell cycle changes of treated HeLa cells were analyzed by flow cytometry. Measurements of gene and microRNA expression levels in treated HeLa cells were done by quantitative real time PCR. Five examined extracts (2–6) exerted selective concentration-dependent cytotoxic effects on HeLa, K562, and A549 cancer cells, while the extract 1 exhibited very weak cytotoxicity. The extract 6 showed the highest intensity of cytotoxic activity. All tested extracts (2–6) demonstrated the ability to induce apoptosis in HeLa cells through activation of caspase-3. These extracts remarkably decreased gene expression levels of MMP2, MMP9, TIMP3, and VEGFA in HeLa cells. Flower extracts might have stronger effects on miR128/193a-5p/335 level changes than branch-body extracts. Hypericum perforatum extracts exerted weaker cytotoxic effects on 3D HeLa spheroids when compared with their effects on 2D monolayer HeLa cells. Taken together, results of our research may suggest the promising anticancer properties of the Hypericum perforatum extracts. © 2021, The Author(s), under exclusive licence to Springer Nature B.V.
T2  - Cytotechnology
T1  - Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models
VL  - 73
IS  - 3
SP  - 373
EP  - 389
DO  - 10.1007/s10616-021-00464-5
ER  - 
@article{
author = "Matić, Ivana Z. and Ergün, Sercan and Đorđić Crnogorac, Marija and Misir, Sema and Aliyazicioğlu, Yüksel and Damjanović, Ana and Džudžević-Čančar, Hurija and Stanojković, Tatjana and Konanç, Kalbiye and Petrović, Nina",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9406",
abstract = "Six extracts were obtained from plant species Hypericum perforatum L., collected at Samsun in Turkey. The aim of this study was to examine the mechanisms of the anticancer activity of these extracts. Methanol, ethyl-acetate and hexane were used as a solvents for extraction from both branch-body part of the plant (extracts 1, 2 and 3) and from plant flowers (extracts 4, 5 and 6). The cytotoxic effects of the extracts were determined against 2D and 3D cancer cell models. Cell cycle changes of treated HeLa cells were analyzed by flow cytometry. Measurements of gene and microRNA expression levels in treated HeLa cells were done by quantitative real time PCR. Five examined extracts (2–6) exerted selective concentration-dependent cytotoxic effects on HeLa, K562, and A549 cancer cells, while the extract 1 exhibited very weak cytotoxicity. The extract 6 showed the highest intensity of cytotoxic activity. All tested extracts (2–6) demonstrated the ability to induce apoptosis in HeLa cells through activation of caspase-3. These extracts remarkably decreased gene expression levels of MMP2, MMP9, TIMP3, and VEGFA in HeLa cells. Flower extracts might have stronger effects on miR128/193a-5p/335 level changes than branch-body extracts. Hypericum perforatum extracts exerted weaker cytotoxic effects on 3D HeLa spheroids when compared with their effects on 2D monolayer HeLa cells. Taken together, results of our research may suggest the promising anticancer properties of the Hypericum perforatum extracts. © 2021, The Author(s), under exclusive licence to Springer Nature B.V.",
journal = "Cytotechnology",
title = "Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models",
volume = "73",
number = "3",
pages = "373-389",
doi = "10.1007/s10616-021-00464-5"
}
Matić, I. Z., Ergün, S., Đorđić Crnogorac, M., Misir, S., Aliyazicioğlu, Y., Damjanović, A., Džudžević-Čančar, H., Stanojković, T., Konanç, K.,& Petrović, N. (2021). Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models.
Cytotechnology, 73(3), 373-389.
https://doi.org/10.1007/s10616-021-00464-5
Matić IZ, Ergün S, Đorđić Crnogorac M, Misir S, Aliyazicioğlu Y, Damjanović A, Džudžević-Čančar H, Stanojković T, Konanç K, Petrović N. Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models. Cytotechnology. 2021;73(3):373-389
Matić Ivana Z., Ergün Sercan, Đorđić Crnogorac Marija, Misir Sema, Aliyazicioğlu Yüksel, Damjanović Ana, Džudžević-Čančar Hurija, Stanojković Tatjana, Konanç Kalbiye, Petrović Nina, "Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models" Cytotechnology, 73, no. 3 (2021):373-389,
https://doi.org/10.1007/s10616-021-00464-5 .

Characterization of B4C-SiC ceramic composites prepared by ultra-high pressure sintering

Matović, Branko; Maletaškić, Jelena; Prikhna, Tatiana; Urbanovich, Vladimir; Girman, Vladimir; Lisnichuk, Maksym; Todorović, Bratislav; Yoshida, Kutsami; Cvijović-Alagić, Ivana

(2021)

TY  - JOUR
AU  - Matović, Branko
AU  - Maletaškić, Jelena
AU  - Prikhna, Tatiana
AU  - Urbanovich, Vladimir
AU  - Girman, Vladimir
AU  - Lisnichuk, Maksym
AU  - Todorović, Bratislav
AU  - Yoshida, Kutsami
AU  - Cvijović-Alagić, Ivana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9405
AB  - Additive-free boron carbide (B4C) – silicon carbide (SiC) ceramic composites with different B4C and β-SiC powders ratio were densified using the high-pressure “anvil-type with hollows” apparatus at 1500 °C under a pressure of 4 GPa for 60 s in air. The effect of starting powders ratio on the composites sintering behavior, relative density, microstructural development, and thermomechanical properties was studied. The sintered samples hardness was found to be in the range from 24 to 31 GPa. The thermal conductivity measurements, conducted in the temperature range from room temperature to 1000 °C, showed that the thermal diffusivity of sintered samples was between 6 and 9.5 mm2/s whereas the thermal conductivity was in the range from 16 to 28 W/(m K). The results of this study show that the high-pressure sintering can be a very effective low-temperature densification method for the obtainment of additive-free B4C - β-SiC ceramic composites. © 2021 Elsevier Ltd
T2  - Journal of the European Ceramic Society
T1  - Characterization of B4C-SiC ceramic composites prepared by ultra-high pressure sintering
VL  - 41
IS  - 9
SP  - 4755
EP  - 4760
DO  - 10.1016/j.jeurceramsoc.2021.03.047
ER  - 
@article{
author = "Matović, Branko and Maletaškić, Jelena and Prikhna, Tatiana and Urbanovich, Vladimir and Girman, Vladimir and Lisnichuk, Maksym and Todorović, Bratislav and Yoshida, Kutsami and Cvijović-Alagić, Ivana",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9405",
abstract = "Additive-free boron carbide (B4C) – silicon carbide (SiC) ceramic composites with different B4C and β-SiC powders ratio were densified using the high-pressure “anvil-type with hollows” apparatus at 1500 °C under a pressure of 4 GPa for 60 s in air. The effect of starting powders ratio on the composites sintering behavior, relative density, microstructural development, and thermomechanical properties was studied. The sintered samples hardness was found to be in the range from 24 to 31 GPa. The thermal conductivity measurements, conducted in the temperature range from room temperature to 1000 °C, showed that the thermal diffusivity of sintered samples was between 6 and 9.5 mm2/s whereas the thermal conductivity was in the range from 16 to 28 W/(m K). The results of this study show that the high-pressure sintering can be a very effective low-temperature densification method for the obtainment of additive-free B4C - β-SiC ceramic composites. © 2021 Elsevier Ltd",
journal = "Journal of the European Ceramic Society",
title = "Characterization of B4C-SiC ceramic composites prepared by ultra-high pressure sintering",
volume = "41",
number = "9",
pages = "4755-4760",
doi = "10.1016/j.jeurceramsoc.2021.03.047"
}
Matović, B., Maletaškić, J., Prikhna, T., Urbanovich, V., Girman, V., Lisnichuk, M., Todorović, B., Yoshida, K.,& Cvijović-Alagić, I. (2021). Characterization of B4C-SiC ceramic composites prepared by ultra-high pressure sintering.
Journal of the European Ceramic Society, 41(9), 4755-4760.
https://doi.org/10.1016/j.jeurceramsoc.2021.03.047
Matović B, Maletaškić J, Prikhna T, Urbanovich V, Girman V, Lisnichuk M, Todorović B, Yoshida K, Cvijović-Alagić I. Characterization of B4C-SiC ceramic composites prepared by ultra-high pressure sintering. Journal of the European Ceramic Society. 2021;41(9):4755-4760
Matović Branko, Maletaškić Jelena, Prikhna Tatiana, Urbanovich Vladimir, Girman Vladimir, Lisnichuk Maksym, Todorović Bratislav, Yoshida Kutsami, Cvijović-Alagić Ivana, "Characterization of B4C-SiC ceramic composites prepared by ultra-high pressure sintering" Journal of the European Ceramic Society, 41, no. 9 (2021):4755-4760,
https://doi.org/10.1016/j.jeurceramsoc.2021.03.047 .
1
1

Effects of Gentiana lutea Root on Vascular Diseases

Joksić, Gordana; Radak, Đorđe; Sudar-Milovanović, Emina; Obradović, Milan M.; Radovanović, Jelena V.; Isenović, Esma R.

(2021)

TY  - JOUR
AU  - Joksić, Gordana
AU  - Radak, Đorđe
AU  - Sudar-Milovanović, Emina
AU  - Obradović, Milan M.
AU  - Radovanović, Jelena V.
AU  - Isenović, Esma R.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9407
AB  - Background: Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and bit-terwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich natural source of iridoids, secoiridoids, xantones, flavonoids, triterpenoids, and carbohydrates. Medicinal plants from Gentiana species have anti-oxidant, anti-inflammatory, anti-mitogenic, anti-proliferative, and lipid-lowering effects, as well as a cardioprotective, hypotensive, vasodilator and anti-platelet activities. Objective: We reviewed the recent literature related to the effects of Gentiana species, and their active components on vascular diseases. Methods: Data used for this review were obtained by searching the electronic database [PUB-MED/MEDLINE 1973-February 2020]. The primary data search terms of interest were: Gentiana lutea, Gentienacea family, phytochemistry, vascular diseases, treatment of vascular diseases, anti-oxidant, anti-inflammatory, anti-atherogenic. Conclusion: Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially use-ful drugs for the management of vascular diseases. © 2021 Bentham Science Publishers.
T2  - Current Vascular Pharmacology
T1  - Effects of Gentiana lutea Root on Vascular Diseases
VL  - 19
IS  - 4
SP  - 359
EP  - 369
DO  - 10.2174/1570161118666200529111314
ER  - 
@article{
author = "Joksić, Gordana and Radak, Đorđe and Sudar-Milovanović, Emina and Obradović, Milan M. and Radovanović, Jelena V. and Isenović, Esma R.",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9407",
abstract = "Background: Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and bit-terwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich natural source of iridoids, secoiridoids, xantones, flavonoids, triterpenoids, and carbohydrates. Medicinal plants from Gentiana species have anti-oxidant, anti-inflammatory, anti-mitogenic, anti-proliferative, and lipid-lowering effects, as well as a cardioprotective, hypotensive, vasodilator and anti-platelet activities. Objective: We reviewed the recent literature related to the effects of Gentiana species, and their active components on vascular diseases. Methods: Data used for this review were obtained by searching the electronic database [PUB-MED/MEDLINE 1973-February 2020]. The primary data search terms of interest were: Gentiana lutea, Gentienacea family, phytochemistry, vascular diseases, treatment of vascular diseases, anti-oxidant, anti-inflammatory, anti-atherogenic. Conclusion: Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially use-ful drugs for the management of vascular diseases. © 2021 Bentham Science Publishers.",
journal = "Current Vascular Pharmacology",
title = "Effects of Gentiana lutea Root on Vascular Diseases",
volume = "19",
number = "4",
pages = "359-369",
doi = "10.2174/1570161118666200529111314"
}
Joksić, G., Radak, Đ., Sudar-Milovanović, E., Obradović, M. M., Radovanović, J. V.,& Isenović, E. R. (2021). Effects of Gentiana lutea Root on Vascular Diseases.
Current Vascular Pharmacology, 19(4), 359-369.
https://doi.org/10.2174/1570161118666200529111314
Joksić G, Radak Đ, Sudar-Milovanović E, Obradović MM, Radovanović JV, Isenović ER. Effects of Gentiana lutea Root on Vascular Diseases. Current Vascular Pharmacology. 2021;19(4):359-369
Joksić Gordana, Radak Đorđe, Sudar-Milovanović Emina, Obradović Milan M., Radovanović Jelena V., Isenović Esma R., "Effects of Gentiana lutea Root on Vascular Diseases" Current Vascular Pharmacology, 19, no. 4 (2021):359-369,
https://doi.org/10.2174/1570161118666200529111314 .
1

Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2

Todorović, Lidija; Stamenković, Gorana; Vučetić-Tadić, Biljana; Umezawa, Kazuo; Božović, Ana M.; Yamashita, Shunichi; Stanojević, Boban

(2021)

TY  - JOUR
AU  - Todorović, Lidija
AU  - Stamenković, Gorana
AU  - Vučetić-Tadić, Biljana
AU  - Umezawa, Kazuo
AU  - Božović, Ana M.
AU  - Yamashita, Shunichi
AU  - Stanojević, Boban
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9413
AB  - The use of targeted inhibitors has shown promise as an effective approach in cancer therapy. However, targeted therapies based only on one drug, such as 17-allylamino-17-demethoxygeldanamycin (17-AAG), have limited success, partly because cancer cells engage alternate pathways for survival and proliferation. In the present study, we evaluated whether dehydroxymethylepoxyquinomicin (DHMEQ), a nuclear factor ?B (NF-?B) inhibitor, can enhance the antitumor activities of 17-AAG, a 90 kDa heat shock protein (Hsp90) inhibitor, in the anaplastic thyroid cancer cell line KTC2. We examined the effect of combined drug treatment vs single drug treatment on cell survival. Isobologram analysis was performed to distinguish the additive vs synergistic effects of the drug combination. Western blotting was performed to investigate apoptosis markers: caspase 3, poly(ADP-ribose) polymerase-one (PARP-1), B-cell lymphoma-extra large (Bcl-XL), X-linked inhibitor of apoptosis (XIAP) and cellular inhibitor of apoptosis 2 (cIAP-2). Compared to monotherapy, the combined treatment enhanced growth-inhibitory effects in a synergistic manner and strongly potentiated apoptosis. These results demonstrate the first in vitro evidence that a combination of Hsp90 and NF-?B inhibitors is a more effective modality for inhibiting cell proliferation and survival in anaplastic thyroid carcinoma cells than either agent alone, warranting further investigations.
T2  - Archives of Biological Sciences
T1  - Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2
VL  - 73
IS  - 1
SP  - 31
EP  - 38
DO  - 10.2298/ABS201010055T
ER  - 
@article{
author = "Todorović, Lidija and Stamenković, Gorana and Vučetić-Tadić, Biljana and Umezawa, Kazuo and Božović, Ana M. and Yamashita, Shunichi and Stanojević, Boban",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9413",
abstract = "The use of targeted inhibitors has shown promise as an effective approach in cancer therapy. However, targeted therapies based only on one drug, such as 17-allylamino-17-demethoxygeldanamycin (17-AAG), have limited success, partly because cancer cells engage alternate pathways for survival and proliferation. In the present study, we evaluated whether dehydroxymethylepoxyquinomicin (DHMEQ), a nuclear factor ?B (NF-?B) inhibitor, can enhance the antitumor activities of 17-AAG, a 90 kDa heat shock protein (Hsp90) inhibitor, in the anaplastic thyroid cancer cell line KTC2. We examined the effect of combined drug treatment vs single drug treatment on cell survival. Isobologram analysis was performed to distinguish the additive vs synergistic effects of the drug combination. Western blotting was performed to investigate apoptosis markers: caspase 3, poly(ADP-ribose) polymerase-one (PARP-1), B-cell lymphoma-extra large (Bcl-XL), X-linked inhibitor of apoptosis (XIAP) and cellular inhibitor of apoptosis 2 (cIAP-2). Compared to monotherapy, the combined treatment enhanced growth-inhibitory effects in a synergistic manner and strongly potentiated apoptosis. These results demonstrate the first in vitro evidence that a combination of Hsp90 and NF-?B inhibitors is a more effective modality for inhibiting cell proliferation and survival in anaplastic thyroid carcinoma cells than either agent alone, warranting further investigations.",
journal = "Archives of Biological Sciences",
title = "Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2",
volume = "73",
number = "1",
pages = "31-38",
doi = "10.2298/ABS201010055T"
}
Todorović, L., Stamenković, G., Vučetić-Tadić, B., Umezawa, K., Božović, A. M., Yamashita, S.,& Stanojević, B. (2021). Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2.
Archives of Biological Sciences, 73(1), 31-38.
https://doi.org/10.2298/ABS201010055T
Todorović L, Stamenković G, Vučetić-Tadić B, Umezawa K, Božović AM, Yamashita S, Stanojević B. Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2. Archives of Biological Sciences. 2021;73(1):31-38
Todorović Lidija, Stamenković Gorana, Vučetić-Tadić Biljana, Umezawa Kazuo, Božović Ana M., Yamashita Shunichi, Stanojević Boban, "Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2" Archives of Biological Sciences, 73, no. 1 (2021):31-38,
https://doi.org/10.2298/ABS201010055T .

Protective effects of pumpkin (Cucurbita pepo L.) seed oil on rat liver damage induced by chronic alcohol consumption

Radić, Ivan; Mirić, Mirjana; Mijović, Milica; Tatalović, Nikola; Mitić, Miloš; Nestorović, Vojkan; Adžić, Miroslav; Blagojević, Duško; Popović, Ljiljana; Janićijević-Hudomal, Snežana

(2021)

TY  - JOUR
AU  - Radić, Ivan
AU  - Mirić, Mirjana
AU  - Mijović, Milica
AU  - Tatalović, Nikola
AU  - Mitić, Miloš
AU  - Nestorović, Vojkan
AU  - Adžić, Miroslav
AU  - Blagojević, Duško
AU  - Popović, Ljiljana
AU  - Janićijević-Hudomal, Snežana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9412
AB  - Pumpkin seed oil (PSO) possesses a protective potential against liver injury due to the presence of biologically active ingredients. Adult male albino rats were administrated PSO (per os, 2 mL/kg b.w./day) and a 12% ethanol solution in water, ad libitum, with an average intake of 8.14 g of ethanol/kg bw/day for 6 weeks. Congestion, hepatic central vein dilation, portal vein branch dilation, Kupffer cell hyperplasia, fatty liver changes, hepatocyte focal necrosis were observed after daily alcohol intake. All observed changes were reduced when PSO was ingested with ethanol. PSO intake itself induced discrete cellular edema, congestion and slight dilatation of the central and portal vain branches. Chronic ethanol intake elevated catalase (CAT) activity and glutathione reductase (GR) protein expression; concomitant PSO intake had no effect on CAT activity or GR protein expression. PSO intake decreased the activities of GR, glutathione-S-transferase (GST) and xanthine oxidase (XOD) in the liver, probably due to the ingestion of antioxidants. Intake of PSO and ethanol significantly decreased cytosolic superoxide dismutase (SOD1) and increased NF-?B protein expression compared to ethanol intake, suggesting that the protective effects of PSO were mediated by the NF-?B signaling pathway. Our results reveal a therapeutic potential of PSO in alcoholic liver disease.
T2  - Archives of Biological Sciences
T1  - Protective effects of pumpkin (Cucurbita pepo L.) seed oil on rat liver damage induced by chronic alcohol consumption
VL  - 73
IS  - 1
SP  - 123
EP  - 133
DO  - 10.2298/ABS201205008R
ER  - 
@article{
author = "Radić, Ivan and Mirić, Mirjana and Mijović, Milica and Tatalović, Nikola and Mitić, Miloš and Nestorović, Vojkan and Adžić, Miroslav and Blagojević, Duško and Popović, Ljiljana and Janićijević-Hudomal, Snežana",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9412",
abstract = "Pumpkin seed oil (PSO) possesses a protective potential against liver injury due to the presence of biologically active ingredients. Adult male albino rats were administrated PSO (per os, 2 mL/kg b.w./day) and a 12% ethanol solution in water, ad libitum, with an average intake of 8.14 g of ethanol/kg bw/day for 6 weeks. Congestion, hepatic central vein dilation, portal vein branch dilation, Kupffer cell hyperplasia, fatty liver changes, hepatocyte focal necrosis were observed after daily alcohol intake. All observed changes were reduced when PSO was ingested with ethanol. PSO intake itself induced discrete cellular edema, congestion and slight dilatation of the central and portal vain branches. Chronic ethanol intake elevated catalase (CAT) activity and glutathione reductase (GR) protein expression; concomitant PSO intake had no effect on CAT activity or GR protein expression. PSO intake decreased the activities of GR, glutathione-S-transferase (GST) and xanthine oxidase (XOD) in the liver, probably due to the ingestion of antioxidants. Intake of PSO and ethanol significantly decreased cytosolic superoxide dismutase (SOD1) and increased NF-?B protein expression compared to ethanol intake, suggesting that the protective effects of PSO were mediated by the NF-?B signaling pathway. Our results reveal a therapeutic potential of PSO in alcoholic liver disease.",
journal = "Archives of Biological Sciences",
title = "Protective effects of pumpkin (Cucurbita pepo L.) seed oil on rat liver damage induced by chronic alcohol consumption",
volume = "73",
number = "1",
pages = "123-133",
doi = "10.2298/ABS201205008R"
}
Radić, I., Mirić, M., Mijović, M., Tatalović, N., Mitić, M., Nestorović, V., Adžić, M., Blagojević, D., Popović, L.,& Janićijević-Hudomal, S. (2021). Protective effects of pumpkin (Cucurbita pepo L.) seed oil on rat liver damage induced by chronic alcohol consumption.
Archives of Biological Sciences, 73(1), 123-133.
https://doi.org/10.2298/ABS201205008R
Radić I, Mirić M, Mijović M, Tatalović N, Mitić M, Nestorović V, Adžić M, Blagojević D, Popović L, Janićijević-Hudomal S. Protective effects of pumpkin (Cucurbita pepo L.) seed oil on rat liver damage induced by chronic alcohol consumption. Archives of Biological Sciences. 2021;73(1):123-133
Radić Ivan, Mirić Mirjana, Mijović Milica, Tatalović Nikola, Mitić Miloš, Nestorović Vojkan, Adžić Miroslav, Blagojević Duško, Popović Ljiljana, Janićijević-Hudomal Snežana, "Protective effects of pumpkin (Cucurbita pepo L.) seed oil on rat liver damage induced by chronic alcohol consumption" Archives of Biological Sciences, 73, no. 1 (2021):123-133,
https://doi.org/10.2298/ABS201205008R .

Adsorption of anthraquinone dye AB111 from aqueous solution using synthesized alumina-iron oxide doped particles

Stupar, Stevan; Vuksanović, Marija M.; Totovski, Ljubica; Jančić-Heinemann, Radmila; Mijin, Dušan

(2021)

TY  - JOUR
AU  - Stupar, Stevan
AU  - Vuksanović, Marija M.
AU  - Totovski, Ljubica
AU  - Jančić-Heinemann, Radmila
AU  - Mijin, Dušan
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9411
AB  - Adsorption of anthraquinone dye Acid Blue 111 by alumina-iron oxide doped particles prepared by sol-gel method from aqueous solutions was studied. The adsorbent morphology was revealed by FESEM and the crystallographic phase is analyzed by the XRD technique. The effect of adsorbate and adsorbent concentrations, pH value, type of adsorbent and thermodynamic parameters on dye removal by adsorption was studied. The change of dye concentration during the adsorbtion was followed using the UV-Visible spectrophotometer. The change of the adsorbent surface before and after dye removal was observed using the Fourier Transformation-infrared spectroscopy (FT-IR). The adsorption kinetics is in accordance with the pseudo-second-order kinetics model. The Langmuir and Freundlich adsorption isotherm models were used to describe the adsorption process. The thermodynamic study of dye adsorption proves the process is spontaneous with exothermic nature. © 2021 Authors. Published by association for ETRAN Society.
T2  - Science of Sintering
T1  - Adsorption of anthraquinone dye AB111 from aqueous solution using synthesized alumina-iron oxide doped particles
VL  - 53
IS  - 1
SP  - 91
EP  - 117
DO  - 10.2298/SOS2101091S
ER  - 
@article{
author = "Stupar, Stevan and Vuksanović, Marija M. and Totovski, Ljubica and Jančić-Heinemann, Radmila and Mijin, Dušan",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9411",
abstract = "Adsorption of anthraquinone dye Acid Blue 111 by alumina-iron oxide doped particles prepared by sol-gel method from aqueous solutions was studied. The adsorbent morphology was revealed by FESEM and the crystallographic phase is analyzed by the XRD technique. The effect of adsorbate and adsorbent concentrations, pH value, type of adsorbent and thermodynamic parameters on dye removal by adsorption was studied. The change of dye concentration during the adsorbtion was followed using the UV-Visible spectrophotometer. The change of the adsorbent surface before and after dye removal was observed using the Fourier Transformation-infrared spectroscopy (FT-IR). The adsorption kinetics is in accordance with the pseudo-second-order kinetics model. The Langmuir and Freundlich adsorption isotherm models were used to describe the adsorption process. The thermodynamic study of dye adsorption proves the process is spontaneous with exothermic nature. © 2021 Authors. Published by association for ETRAN Society.",
journal = "Science of Sintering",
title = "Adsorption of anthraquinone dye AB111 from aqueous solution using synthesized alumina-iron oxide doped particles",
volume = "53",
number = "1",
pages = "91-117",
doi = "10.2298/SOS2101091S"
}
Stupar, S., Vuksanović, M. M., Totovski, L., Jančić-Heinemann, R.,& Mijin, D. (2021). Adsorption of anthraquinone dye AB111 from aqueous solution using synthesized alumina-iron oxide doped particles.
Science of Sintering, 53(1), 91-117.
https://doi.org/10.2298/SOS2101091S
Stupar S, Vuksanović MM, Totovski L, Jančić-Heinemann R, Mijin D. Adsorption of anthraquinone dye AB111 from aqueous solution using synthesized alumina-iron oxide doped particles. Science of Sintering. 2021;53(1):91-117
Stupar Stevan, Vuksanović Marija M., Totovski Ljubica, Jančić-Heinemann Radmila, Mijin Dušan, "Adsorption of anthraquinone dye AB111 from aqueous solution using synthesized alumina-iron oxide doped particles" Science of Sintering, 53, no. 1 (2021):91-117,
https://doi.org/10.2298/SOS2101091S .

Multiferroic heterostructure BaTiO3/ε-Fe2O3 composite obtained by in situ reaction

Filipović, Suzana; Obradović, Nina; Anđelković, Ljubica; Olćan, Dragan; Petrović, Jovana; Mirković, Miljana M.; Pavlović, Vladimir B.; Jeremić, Dejan; Vlahović, Branislav; Đorđević, Antonije

(2021)

TY  - JOUR
AU  - Filipović, Suzana
AU  - Obradović, Nina
AU  - Anđelković, Ljubica
AU  - Olćan, Dragan
AU  - Petrović, Jovana
AU  - Mirković, Miljana M.
AU  - Pavlović, Vladimir B.
AU  - Jeremić, Dejan
AU  - Vlahović, Branislav
AU  - Đorđević, Antonije
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9410
AB  - Solid-state reaction between BaTiO3and Fe2O3was used to produce a multiferroic heterostructure composite. Commercial BaTiO3and Fe(NO3)3•9H2O were suspended in ethanol for 30 minutes in an ultrasound bath. The prepared mixture was thermally processed at 300°C for 6 h. Sintering at 1300 °C for 1 h resulted in a mixture of different phases, BaTiO3, BaFe12O19and Ba12Ti28Fe15O84, which were confirmed by x-ray powder diffraction. A dense microstructure with a small volume fraction of closed porosity was indicated by the scanning electron microscopy, while a homogeneous distribution of Fe ions over BaTiO3phase was visible from energy dispersive spectroscopy mapping. Doping of BaTiO3with Fe2O3resulted in formation of magnetic hexaferrite phases, as confirmed by dielectric measurements that showed a broadened maximum of the permittivity measured as a function of temperature. © 2021 Authors. Published by association for ETRAN Society.
T2  - Science of Sintering
T1  - Multiferroic heterostructure BaTiO3/ε-Fe2O3 composite obtained by in situ reaction
VL  - 53
IS  - 1
SP  - 1
EP  - 8
DO  - 10.2298/SOS2101001F
ER  - 
@article{
author = "Filipović, Suzana and Obradović, Nina and Anđelković, Ljubica and Olćan, Dragan and Petrović, Jovana and Mirković, Miljana M. and Pavlović, Vladimir B. and Jeremić, Dejan and Vlahović, Branislav and Đorđević, Antonije",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9410",
abstract = "Solid-state reaction between BaTiO3and Fe2O3was used to produce a multiferroic heterostructure composite. Commercial BaTiO3and Fe(NO3)3•9H2O were suspended in ethanol for 30 minutes in an ultrasound bath. The prepared mixture was thermally processed at 300°C for 6 h. Sintering at 1300 °C for 1 h resulted in a mixture of different phases, BaTiO3, BaFe12O19and Ba12Ti28Fe15O84, which were confirmed by x-ray powder diffraction. A dense microstructure with a small volume fraction of closed porosity was indicated by the scanning electron microscopy, while a homogeneous distribution of Fe ions over BaTiO3phase was visible from energy dispersive spectroscopy mapping. Doping of BaTiO3with Fe2O3resulted in formation of magnetic hexaferrite phases, as confirmed by dielectric measurements that showed a broadened maximum of the permittivity measured as a function of temperature. © 2021 Authors. Published by association for ETRAN Society.",
journal = "Science of Sintering",
title = "Multiferroic heterostructure BaTiO3/ε-Fe2O3 composite obtained by in situ reaction",
volume = "53",
number = "1",
pages = "1-8",
doi = "10.2298/SOS2101001F"
}
Filipović, S., Obradović, N., Anđelković, L., Olćan, D., Petrović, J., Mirković, M. M., Pavlović, V. B., Jeremić, D., Vlahović, B.,& Đorđević, A. (2021). Multiferroic heterostructure BaTiO3/ε-Fe2O3 composite obtained by in situ reaction.
Science of Sintering, 53(1), 1-8.
https://doi.org/10.2298/SOS2101001F
Filipović S, Obradović N, Anđelković L, Olćan D, Petrović J, Mirković MM, Pavlović VB, Jeremić D, Vlahović B, Đorđević A. Multiferroic heterostructure BaTiO3/ε-Fe2O3 composite obtained by in situ reaction. Science of Sintering. 2021;53(1):1-8
Filipović Suzana, Obradović Nina, Anđelković Ljubica, Olćan Dragan, Petrović Jovana, Mirković Miljana M., Pavlović Vladimir B., Jeremić Dejan, Vlahović Branislav, Đorđević Antonije, "Multiferroic heterostructure BaTiO3/ε-Fe2O3 composite obtained by in situ reaction" Science of Sintering, 53, no. 1 (2021):1-8,
https://doi.org/10.2298/SOS2101001F .

Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent

Zmejkoski, Danica; Marković, Zoran M.; Zdravković, Nemanja M.; Trišić, Dijana D.; Budimir, Milica; Kuzman, Sanja; Kozyrovska, Natalia O.; Orlovska, Iryna V.; Bugárová, Nikol; Petrović, Đorđe; Kováčová, Mária; Kleinová, Angela; Špitalský, Zdeno; Pavlović, Vladimir B.; Todorović-Marković, Biljana

(2021)

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Marković, Zoran M.
AU  - Zdravković, Nemanja M.
AU  - Trišić, Dijana D.
AU  - Budimir, Milica
AU  - Kuzman, Sanja
AU  - Kozyrovska, Natalia O.
AU  - Orlovska, Iryna V.
AU  - Bugárová, Nikol
AU  - Petrović, Đorđe
AU  - Kováčová, Mária
AU  - Kleinová, Angela
AU  - Špitalský, Zdeno
AU  - Pavlović, Vladimir B.
AU  - Todorović-Marković, Biljana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9143
AB  - Therapy of bacterial urinary tract infections (UTIs) and catheter associated urinary tract infections (CAUTIs) is still a great challenge because of the resistance of bacteria to nowadays used antibiotics and encrustation of catheters. Bacterial cellulose (BC) as a biocompatible material with a high porosity allows incorporation of different materials in its three dimensional network structure. In this work a low molecular weight chitosan (Chi) polymer is incorporated in BC with different concentrations. Different characterization techniques are used to investigate structural and optical properties of these composites. Radical scavenging activity test shows moderate antioxidant activity of these biocompatible composites whereasin vitrorelease test shows that 13.3% of chitosan is released after 72 h. Antibacterial testing of BC-Chi composites conducted on Gram-positive and Gram-negative bacteria causing UTIs and CAUTIs (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae) and encrustation (Proteus mirabilis) show bactericidal effect. The morphology analysis of bacteria after the application of BC-Chi shows that they are flattened with a rough surface, with a tendency to agglomerate and with decreased length and width. All obtained results show that BC-Chi composites might be considered as potential biomedical agents in treatment of UTIs and CAUTIs and as a urinary catheter coating in encrustation prevention.
T2  - RSC Advances
T1  - Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent
VL  - 11
IS  - 15
SP  - 8559
EP  - 8568
DO  - 10.1039/D0RA10782D
ER  - 
@article{
author = "Zmejkoski, Danica and Marković, Zoran M. and Zdravković, Nemanja M. and Trišić, Dijana D. and Budimir, Milica and Kuzman, Sanja and Kozyrovska, Natalia O. and Orlovska, Iryna V. and Bugárová, Nikol and Petrović, Đorđe and Kováčová, Mária and Kleinová, Angela and Špitalský, Zdeno and Pavlović, Vladimir B. and Todorović-Marković, Biljana",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9143",
abstract = "Therapy of bacterial urinary tract infections (UTIs) and catheter associated urinary tract infections (CAUTIs) is still a great challenge because of the resistance of bacteria to nowadays used antibiotics and encrustation of catheters. Bacterial cellulose (BC) as a biocompatible material with a high porosity allows incorporation of different materials in its three dimensional network structure. In this work a low molecular weight chitosan (Chi) polymer is incorporated in BC with different concentrations. Different characterization techniques are used to investigate structural and optical properties of these composites. Radical scavenging activity test shows moderate antioxidant activity of these biocompatible composites whereasin vitrorelease test shows that 13.3% of chitosan is released after 72 h. Antibacterial testing of BC-Chi composites conducted on Gram-positive and Gram-negative bacteria causing UTIs and CAUTIs (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae) and encrustation (Proteus mirabilis) show bactericidal effect. The morphology analysis of bacteria after the application of BC-Chi shows that they are flattened with a rough surface, with a tendency to agglomerate and with decreased length and width. All obtained results show that BC-Chi composites might be considered as potential biomedical agents in treatment of UTIs and CAUTIs and as a urinary catheter coating in encrustation prevention.",
journal = "RSC Advances",
title = "Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent",
volume = "11",
number = "15",
pages = "8559-8568",
doi = "10.1039/D0RA10782D"
}
Zmejkoski, D., Marković, Z. M., Zdravković, N. M., Trišić, D. D., Budimir, M., Kuzman, S., Kozyrovska, N. O., Orlovska, I. V., Bugárová, N., Petrović, Đ., Kováčová, M., Kleinová, A., Špitalský, Z., Pavlović, V. B.,& Todorović-Marković, B. (2021). Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent.
RSC Advances, 11(15), 8559-8568.
https://doi.org/10.1039/D0RA10782D
Zmejkoski D, Marković ZM, Zdravković NM, Trišić DD, Budimir M, Kuzman S, Kozyrovska NO, Orlovska IV, Bugárová N, Petrović Đ, Kováčová M, Kleinová A, Špitalský Z, Pavlović VB, Todorović-Marković B. Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent. RSC Advances. 2021;11(15):8559-8568
Zmejkoski Danica, Marković Zoran M., Zdravković Nemanja M., Trišić Dijana D., Budimir Milica, Kuzman Sanja, Kozyrovska Natalia O., Orlovska Iryna V., Bugárová Nikol, Petrović Đorđe, Kováčová Mária, Kleinová Angela, Špitalský Zdeno, Pavlović Vladimir B., Todorović-Marković Biljana, "Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent" RSC Advances, 11, no. 15 (2021):8559-8568,
https://doi.org/10.1039/D0RA10782D .

Advanced damage resistance monitoring procedure on the composite materials’ surface-exposed to cavitation testing

Vuksanović, Marija M.; Gajić-Kvaščev, Maja; Volkov-Husović, Tatjana; Jančić-Heinemann, Radmila

(2021)

TY  - JOUR
AU  - Vuksanović, Marija M.
AU  - Gajić-Kvaščev, Maja
AU  - Volkov-Husović, Tatjana
AU  - Jančić-Heinemann, Radmila
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9162
AB  - Morphology and development of surface damage of alumina-based materials, resulting from cavitation erosion is studied in this paper. Two series of samples were prepared: samples without fibers and those with the addition of 2 wt % of ceramic fibers. The form of surface damage is considered to be the information carrier for the analysis of the resistance of materials to cavitation and the quality of this information is determined. The surface of the samples was monitored in defined time intervals in order to prepare the digitized image suitable for further analysis using image analysis software. The principal component analysis was applied to examine the appearance of certain morphological characteristics depending on the behavior of the material during cavitation erosion. It was concluded that the addition of ceramic fibers gained in importance after a long time of cavitation erosion, while during a starting period of time the difference in the morphology of the damage is not very observable. © 2021 Elsevier B.V.
T2  - Wear
T1  - Advanced damage resistance monitoring procedure on the composite materials’ surface-exposed to cavitation testing
VL  - 474-475
SP  - 203877
DO  - 10.1016/j.wear.2021.203877
ER  - 
@article{
author = "Vuksanović, Marija M. and Gajić-Kvaščev, Maja and Volkov-Husović, Tatjana and Jančić-Heinemann, Radmila",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9162",
abstract = "Morphology and development of surface damage of alumina-based materials, resulting from cavitation erosion is studied in this paper. Two series of samples were prepared: samples without fibers and those with the addition of 2 wt % of ceramic fibers. The form of surface damage is considered to be the information carrier for the analysis of the resistance of materials to cavitation and the quality of this information is determined. The surface of the samples was monitored in defined time intervals in order to prepare the digitized image suitable for further analysis using image analysis software. The principal component analysis was applied to examine the appearance of certain morphological characteristics depending on the behavior of the material during cavitation erosion. It was concluded that the addition of ceramic fibers gained in importance after a long time of cavitation erosion, while during a starting period of time the difference in the morphology of the damage is not very observable. © 2021 Elsevier B.V.",
journal = "Wear",
title = "Advanced damage resistance monitoring procedure on the composite materials’ surface-exposed to cavitation testing",
volume = "474-475",
pages = "203877",
doi = "10.1016/j.wear.2021.203877"
}
Vuksanović, M. M., Gajić-Kvaščev, M., Volkov-Husović, T.,& Jančić-Heinemann, R. (2021). Advanced damage resistance monitoring procedure on the composite materials’ surface-exposed to cavitation testing.
Wear, 474-475, 203877.
https://doi.org/10.1016/j.wear.2021.203877
Vuksanović MM, Gajić-Kvaščev M, Volkov-Husović T, Jančić-Heinemann R. Advanced damage resistance monitoring procedure on the composite materials’ surface-exposed to cavitation testing. Wear. 2021;474-475:203877
Vuksanović Marija M., Gajić-Kvaščev Maja, Volkov-Husović Tatjana, Jančić-Heinemann Radmila, "Advanced damage resistance monitoring procedure on the composite materials’ surface-exposed to cavitation testing" Wear, 474-475 (2021):203877,
https://doi.org/10.1016/j.wear.2021.203877 .

Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at √s = 13 TeV

Sirunyan, A M; Tumasyan, A; Adam, W; Ambrogi, F; Adžić, Petar; Ćirković, Predrag; Đorđević, Miloš; Milenović, Predrag; Milošević, Jovan; Stojanović, Milan

(2021)

TY  - JOUR
AU  - Sirunyan, A M
AU  - Tumasyan, A
AU  - Adam, W
AU  - Ambrogi, F
AU  - Adžić, Petar
AU  - Ćirković, Predrag
AU  - Đorđević, Miloš
AU  - Milenović, Predrag
AU  - Milošević, Jovan
AU  - Stojanović, Milan
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9404
AB  - Measurements of the fiducial inclusive and differential production cross sections of the Higgs boson in proton-proton collisions at s = 13 TeV are performed using events where the Higgs boson decays into a pair of W bosons that subsequently decay into a final state with an electron, a muon, and a pair of neutrinos. The analysis is based on data collected with the CMS detector at the LHC during 2016–2018, corresponding to an integrated luminosity of 137 fb−1. Production cross sections are measured as a function of the transverse momentum of the Higgs boson and the associated jet multiplicity. The Higgs boson signal is extracted and simultaneously unfolded to correct for selection efficiency and resolution effects using maximum-likelihood fits to the observed distributions in data. The integrated fiducial cross section is measured to be 86.5 ± 9.5 fb, consistent with the Standard Model expectation of 82.5 ± 4.2 fb. No significant deviation from the Standard Model expectations is observed in the differential measurements. [Figure not available: see fulltext.] © 2021, The Author(s).
T2  - Journal of High Energy Physics
T1  - Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at √s = 13 TeV
VL  - 2021
IS  - 3
DO  - 10.1007/JHEP03(2021)003
ER  - 
@article{
author = "Sirunyan, A M and Tumasyan, A and Adam, W and Ambrogi, F and Adžić, Petar and Ćirković, Predrag and Đorđević, Miloš and Milenović, Predrag and Milošević, Jovan and Stojanović, Milan",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9404",
abstract = "Measurements of the fiducial inclusive and differential production cross sections of the Higgs boson in proton-proton collisions at s = 13 TeV are performed using events where the Higgs boson decays into a pair of W bosons that subsequently decay into a final state with an electron, a muon, and a pair of neutrinos. The analysis is based on data collected with the CMS detector at the LHC during 2016–2018, corresponding to an integrated luminosity of 137 fb−1. Production cross sections are measured as a function of the transverse momentum of the Higgs boson and the associated jet multiplicity. The Higgs boson signal is extracted and simultaneously unfolded to correct for selection efficiency and resolution effects using maximum-likelihood fits to the observed distributions in data. The integrated fiducial cross section is measured to be 86.5 ± 9.5 fb, consistent with the Standard Model expectation of 82.5 ± 4.2 fb. No significant deviation from the Standard Model expectations is observed in the differential measurements. [Figure not available: see fulltext.] © 2021, The Author(s).",
journal = "Journal of High Energy Physics",
title = "Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at √s = 13 TeV",
volume = "2021",
number = "3",
doi = "10.1007/JHEP03(2021)003"
}
Sirunyan, A. M., Tumasyan, A., Adam, W., Ambrogi, F., Adžić, P., Ćirković, P., Đorđević, M., Milenović, P., Milošević, J.,& Stojanović, M. (2021). Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at √s = 13 TeV.
Journal of High Energy Physics, 2021(3).
https://doi.org/10.1007/JHEP03(2021)003
Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Adžić P, Ćirković P, Đorđević M, Milenović P, Milošević J, Stojanović M. Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at √s = 13 TeV. Journal of High Energy Physics. 2021;2021(3)
Sirunyan A M, Tumasyan A, Adam W, Ambrogi F, Adžić Petar, Ćirković Predrag, Đorđević Miloš, Milenović Predrag, Milošević Jovan, Stojanović Milan, "Measurement of the inclusive and differential Higgs boson production cross sections in the leptonic WW decay mode at √s = 13 TeV" Journal of High Energy Physics, 2021, no. 3 (2021),
https://doi.org/10.1007/JHEP03(2021)003 .
2
4

Histological Evaluation of Periradicular Tissue Inflammatory Reactions and Calcified Tissue Formations after Implantation of Experimental Calcium Silicate and Hydroxyapatite Based Nanostructural Cements into Root Canals of Rabbits Teeth

Petrović, Violeta; Opačić-Galić, Vanja; Jokanović, Vukoman; Sopta, Jelena; Prokić, Bogomir Bolka; Živković, Slavoljub

(2021)


                                            

                                            
Petrović, V., Opačić-Galić, V., Jokanović, V., Sopta, J., Prokić, B. B.,& Živković, S. (2021). Histološka analiza zapaljenskih reakcija u periradikularnom tkivu i formiranja kalcifikovanog tkiva posle implantacije eksperimentalnih nanostrukturnih cemenata na bazi kalcijum silikata i hidroksiapatita u kanale korena zuba kunića.
Acta Veterinaria-Beograd, 71(1), 85-97.
https://doi.org/10.2478/acve-2021-0006
Petrović V, Opačić-Galić V, Jokanović V, Sopta J, Prokić BB, Živković S. Histološka analiza zapaljenskih reakcija u periradikularnom tkivu i formiranja kalcifikovanog tkiva posle implantacije eksperimentalnih nanostrukturnih cemenata na bazi kalcijum silikata i hidroksiapatita u kanale korena zuba kunića. Acta Veterinaria-Beograd. 2021;71(1):85-97
Petrović Violeta, Opačić-Galić Vanja, Jokanović Vukoman, Sopta Jelena, Prokić Bogomir Bolka, Živković Slavoljub, "Histološka analiza zapaljenskih reakcija u periradikularnom tkivu i formiranja kalcifikovanog tkiva posle implantacije eksperimentalnih nanostrukturnih cemenata na bazi kalcijum silikata i hidroksiapatita u kanale korena zuba kunića" Acta Veterinaria-Beograd, 71, no. 1 (2021):85-97,
https://doi.org/10.2478/acve-2021-0006 .

Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia

Zeisig, Bernd B.; Fung, Tsz Kan; Zarowiecki, Magdalena; Tsai, Chiou Tsun; Luo, Huacheng; Stanojević, Boban; Lynn, Claire; Leung, Anskar Y.H.; Zuna, Jan; Zaliova, Marketa; Bornhauser, Martin; von Bonin, Malte; Lenhard, Boris; Huang, Suming; Mufti, Ghulam J.; So, Chi Wai Eric

(2021)

TY  - JOUR
AU  - Zeisig, Bernd B.
AU  - Fung, Tsz Kan
AU  - Zarowiecki, Magdalena
AU  - Tsai, Chiou Tsun
AU  - Luo, Huacheng
AU  - Stanojević, Boban
AU  - Lynn, Claire
AU  - Leung, Anskar Y.H.
AU  - Zuna, Jan
AU  - Zaliova, Marketa
AU  - Bornhauser, Martin
AU  - von Bonin, Malte
AU  - Lenhard, Boris
AU  - Huang, Suming
AU  - Mufti, Ghulam J.
AU  - So, Chi Wai Eric
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9142
AB  - Chemoresistance remains the major challenge for successful treatment of acute myeloid leukemia (AML). Although recent mouse studies suggest that treatment response of genetically and immunophenotypically indistinguishable AML can be influenced by their different cells of origin, corresponding evidence in human disease is still largely lacking. By combining prospective disease modeling using highly purified human hematopoietic stem or progenitor cells with retrospective deconvolution study of leukemia stem cells (LSCs) from primary patient samples, we identified human hematopoietic stem cells (HSCs) and common myeloid progenitors (CMPs) as two distinctive origins of human AML driven by Mixed Lineage Leukemia (MLL) gene fusions (MLL-AML). Despite LSCs from either MLL-rearranged HSCs or MLL-rearranged CMPs having a mature CD34 −/lo /CD38 + immunophenotype in both a humanized mouse model and primary patient samples, the resulting AML cells exhibited contrasting responses to chemotherapy. HSC-derived MLL-AML was highly resistant to chemotherapy and expressed elevated amounts of the multispecific anion transporter ABCC3. Inhibition of ABCC3 by shRNA-mediated knockdown or with small-molecule inhibitor fidaxomicin, currently used for diarrhea associated with Clostridium difficile infection, effectively resensitized HSC-derived MLL-AML toward standard chemotherapeutic drugs. This study not only functionally established two distinctive origins of human LSCs for MLL-AML and their role in mediating chemoresistance but also identified a potential therapeutic avenue for stem cell–associated treatment resistance by repurposing a well-tolerated antidiarrhea drug already used in the clinic.
T2  - Science Translational Medicine
T1  - Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia
VL  - 13
IS  - 582
SP  - eabc4822
DO  - 10.1126/scitranslmed.abc4822
ER  - 
@article{
author = "Zeisig, Bernd B. and Fung, Tsz Kan and Zarowiecki, Magdalena and Tsai, Chiou Tsun and Luo, Huacheng and Stanojević, Boban and Lynn, Claire and Leung, Anskar Y.H. and Zuna, Jan and Zaliova, Marketa and Bornhauser, Martin and von Bonin, Malte and Lenhard, Boris and Huang, Suming and Mufti, Ghulam J. and So, Chi Wai Eric",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9142",
abstract = "Chemoresistance remains the major challenge for successful treatment of acute myeloid leukemia (AML). Although recent mouse studies suggest that treatment response of genetically and immunophenotypically indistinguishable AML can be influenced by their different cells of origin, corresponding evidence in human disease is still largely lacking. By combining prospective disease modeling using highly purified human hematopoietic stem or progenitor cells with retrospective deconvolution study of leukemia stem cells (LSCs) from primary patient samples, we identified human hematopoietic stem cells (HSCs) and common myeloid progenitors (CMPs) as two distinctive origins of human AML driven by Mixed Lineage Leukemia (MLL) gene fusions (MLL-AML). Despite LSCs from either MLL-rearranged HSCs or MLL-rearranged CMPs having a mature CD34 −/lo /CD38 + immunophenotype in both a humanized mouse model and primary patient samples, the resulting AML cells exhibited contrasting responses to chemotherapy. HSC-derived MLL-AML was highly resistant to chemotherapy and expressed elevated amounts of the multispecific anion transporter ABCC3. Inhibition of ABCC3 by shRNA-mediated knockdown or with small-molecule inhibitor fidaxomicin, currently used for diarrhea associated with Clostridium difficile infection, effectively resensitized HSC-derived MLL-AML toward standard chemotherapeutic drugs. This study not only functionally established two distinctive origins of human LSCs for MLL-AML and their role in mediating chemoresistance but also identified a potential therapeutic avenue for stem cell–associated treatment resistance by repurposing a well-tolerated antidiarrhea drug already used in the clinic.",
journal = "Science Translational Medicine",
title = "Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia",
volume = "13",
number = "582",
pages = "eabc4822",
doi = "10.1126/scitranslmed.abc4822"
}
Zeisig, B. B., Fung, T. K., Zarowiecki, M., Tsai, C. T., Luo, H., Stanojević, B., Lynn, C., Leung, A. Y.H., Zuna, J., Zaliova, M., Bornhauser, M., von Bonin, M., Lenhard, B., Huang, S., Mufti, G. J.,& So, C. W. E. (2021). Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia.
Science Translational Medicine, 13(582), eabc4822.
https://doi.org/10.1126/scitranslmed.abc4822
Zeisig BB, Fung TK, Zarowiecki M, Tsai CT, Luo H, Stanojević B, Lynn C, Leung AY, Zuna J, Zaliova M, Bornhauser M, von Bonin M, Lenhard B, Huang S, Mufti GJ, So CWE. Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia. Science Translational Medicine. 2021;13(582):eabc4822
Zeisig Bernd B., Fung Tsz Kan, Zarowiecki Magdalena, Tsai Chiou Tsun, Luo Huacheng, Stanojević Boban, Lynn Claire, Leung Anskar Y.H., Zuna Jan, Zaliova Marketa, Bornhauser Martin, von Bonin Malte, Lenhard Boris, Huang Suming, Mufti Ghulam J., So Chi Wai Eric, "Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia" Science Translational Medicine, 13, no. 582 (2021):eabc4822,
https://doi.org/10.1126/scitranslmed.abc4822 .
44
1

Exploring UiO-66(Zr) frameworks as nanotraps for highly efficient removal of EDTA-complexed heavy metals from water

Lou, Xiaofei; Wu, Yi-nan; Kabtamu, Daniel Manaye; Matović, Ljiljana; Zhang, Yanxing; Sun, Xianyi; Schott, Eduardo; Chu, Wenhai; Li, Fengting

(2021)

TY  - JOUR
AU  - Lou, Xiaofei
AU  - Wu, Yi-nan
AU  - Kabtamu, Daniel Manaye
AU  - Matović, Ljiljana
AU  - Zhang, Yanxing
AU  - Sun, Xianyi
AU  - Schott, Eduardo
AU  - Chu, Wenhai
AU  - Li, Fengting
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8919
AB  - Metal-organic frameworks (MOFs), an exciting class of porous crystalline materials, are suitable for adsorptive removal of toxic heavy metal-ethylenediaminetetraacetic acid (M-EDTA) complexes from wastewater. In this paper, water-stable UiO-66(Zr) with well-defined morphology was successfully synthesized through a facile microwave-assisted solvothermal method and employed as nanotraps for the efficient capture of the three M-EDTA complexes, Cu-EDTA, Pb-EDTA, and Ni-EDTA. The adsorption behaviors, effects of solution pH and co-existing anions, as well as the eluant and desorption were investigated. The obtained UiO-66(Zr) showed good stability and excellent uptake capacity of M-EDTA in a wide pH range (3.0-10.0). UiO-66(Zr) exhibited a higher removal efficiency of Cu-EDTA (57.56 mg/g), Pb-EDTA (120.6 mg/g), and Ni-EDTA (54.27 mg/g). Based on the overall analysis results, our findings show that EDTA-metal complex ions can be adsorbed inside UiO-66(Zr) mainly through the Lewis-acid/-base interactions and possible anion-πinteraction with strong binding energies. Size-matching EDTA-metal complexes confined in the UiO-66(Zr) with flexible geometry would also contribute to the fast adsorption kinetics as well as the selective adsorption of different M-EDTA complexes. © 2020 Elsevier Ltd.
T2  - Journal of Environmental Chemical Engineering
T1  - Exploring UiO-66(Zr) frameworks as nanotraps for highly efficient removal of EDTA-complexed heavy metals from water
VL  - 9
IS  - 1
SP  - 104932
DO  - 10.1016/j.jece.2020.104932
ER  - 
@article{
author = "Lou, Xiaofei and Wu, Yi-nan and Kabtamu, Daniel Manaye and Matović, Ljiljana and Zhang, Yanxing and Sun, Xianyi and Schott, Eduardo and Chu, Wenhai and Li, Fengting",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/8919",
abstract = "Metal-organic frameworks (MOFs), an exciting class of porous crystalline materials, are suitable for adsorptive removal of toxic heavy metal-ethylenediaminetetraacetic acid (M-EDTA) complexes from wastewater. In this paper, water-stable UiO-66(Zr) with well-defined morphology was successfully synthesized through a facile microwave-assisted solvothermal method and employed as nanotraps for the efficient capture of the three M-EDTA complexes, Cu-EDTA, Pb-EDTA, and Ni-EDTA. The adsorption behaviors, effects of solution pH and co-existing anions, as well as the eluant and desorption were investigated. The obtained UiO-66(Zr) showed good stability and excellent uptake capacity of M-EDTA in a wide pH range (3.0-10.0). UiO-66(Zr) exhibited a higher removal efficiency of Cu-EDTA (57.56 mg/g), Pb-EDTA (120.6 mg/g), and Ni-EDTA (54.27 mg/g). Based on the overall analysis results, our findings show that EDTA-metal complex ions can be adsorbed inside UiO-66(Zr) mainly through the Lewis-acid/-base interactions and possible anion-πinteraction with strong binding energies. Size-matching EDTA-metal complexes confined in the UiO-66(Zr) with flexible geometry would also contribute to the fast adsorption kinetics as well as the selective adsorption of different M-EDTA complexes. © 2020 Elsevier Ltd.",
journal = "Journal of Environmental Chemical Engineering",
title = "Exploring UiO-66(Zr) frameworks as nanotraps for highly efficient removal of EDTA-complexed heavy metals from water",
volume = "9",
number = "1",
pages = "104932",
doi = "10.1016/j.jece.2020.104932"
}
Lou, X., Wu, Y., Kabtamu, D. M., Matović, L., Zhang, Y., Sun, X., Schott, E., Chu, W.,& Li, F. (2021). Exploring UiO-66(Zr) frameworks as nanotraps for highly efficient removal of EDTA-complexed heavy metals from water.
Journal of Environmental Chemical Engineering, 9(1), 104932.
https://doi.org/10.1016/j.jece.2020.104932
Lou X, Wu Y, Kabtamu DM, Matović L, Zhang Y, Sun X, Schott E, Chu W, Li F. Exploring UiO-66(Zr) frameworks as nanotraps for highly efficient removal of EDTA-complexed heavy metals from water. Journal of Environmental Chemical Engineering. 2021;9(1):104932
Lou Xiaofei, Wu Yi-nan, Kabtamu Daniel Manaye, Matović Ljiljana, Zhang Yanxing, Sun Xianyi, Schott Eduardo, Chu Wenhai, Li Fengting, "Exploring UiO-66(Zr) frameworks as nanotraps for highly efficient removal of EDTA-complexed heavy metals from water" Journal of Environmental Chemical Engineering, 9, no. 1 (2021):104932,
https://doi.org/10.1016/j.jece.2020.104932 .
1

Cell wall response to UV radiation in needles of Picea omorika

Mitrović, Aleksandra Lj.; Simonović-Radosavljević, Jasna; Prokopijević, Miloš; Spasojević, Dragica; Kovačević, Jovana; Prodanović, Olivera; Todorović, Bratislav; Matović, Branko; Stanković, Mira; Maksimović, Vuk; Mutavdžić, Dragosav; Skočić, Miloš; Pešić, Mirjana; Prokić, Ljiljana; Radotić, Ksenija

(2021)

TY  - JOUR
AU  - Mitrović, Aleksandra Lj.
AU  - Simonović-Radosavljević, Jasna
AU  - Prokopijević, Miloš
AU  - Spasojević, Dragica
AU  - Kovačević, Jovana
AU  - Prodanović, Olivera
AU  - Todorović, Bratislav
AU  - Matović, Branko
AU  - Stanković, Mira
AU  - Maksimović, Vuk
AU  - Mutavdžić, Dragosav
AU  - Skočić, Miloš
AU  - Pešić, Mirjana
AU  - Prokić, Ljiljana
AU  - Radotić, Ksenija
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9129
AB  - The UV-B represents the minor fraction of the solar spectrum, while UV-C is not contained in natural solar radiation, but both radiation types can cause damaging effects in plants. Cell walls (CWs) are one of the targets for external stressors. Juvenile P. omorika trees were treated either with 21 day-high doses UV-B or with 7 day- UV-C in open-top chambers. Using spectroscopic and biochemical techniques, it was shown that the response to UV radiation includes numerous modifications in needle CW structure: relative content of xylan, xyloglucan, lignin and cellulose decreased; cellulose crystallinity changed; yield of lignin monomers with stronger connection of C[dbnd]C in side chain with the ring increased; re-distribution of inter- and intra-polymer H-bonds occurred. The recovery was mediated by an increase in the activities and changes in isoform profiles of CW bound covalent peroxidases (POD) and polyphenol oxidases (PO) (UV–B), and ionic POD and covalent PO (UV–C). A connection between activities of specific POD/PO isoforms and phenolic species (m- and p-coumaric acid, pinoresinol and cinnamic acid derivatives) was demonstrated, and supported by changes in the sRNA profile. In vivo fluorometry showed phenolics accumulation in needle epidermal CWs. These results imply transversal connections between polymers and changed mechanical properties of needle CW as a response to UV. The CW alterations enabled maintenance of physiological functions, as indicated by the preserved chlorophyll content and/or organization. The current study provides evidence that in conifers, needle CW response to both UV-B and UV-C includes biochemical modifications and structural remodeling. © 2021 Elsevier Masson SAS
T2  - Plant Physiology and Biochemistry
T1  - Cell wall response to UV radiation in needles of Picea omorika
VL  - 161
SP  - 176
EP  - 190
DO  - 10.1016/j.plaphy.2021.02.007
ER  - 
@article{
author = "Mitrović, Aleksandra Lj. and Simonović-Radosavljević, Jasna and Prokopijević, Miloš and Spasojević, Dragica and Kovačević, Jovana and Prodanović, Olivera and Todorović, Bratislav and Matović, Branko and Stanković, Mira and Maksimović, Vuk and Mutavdžić, Dragosav and Skočić, Miloš and Pešić, Mirjana and Prokić, Ljiljana and Radotić, Ksenija",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9129",
abstract = "The UV-B represents the minor fraction of the solar spectrum, while UV-C is not contained in natural solar radiation, but both radiation types can cause damaging effects in plants. Cell walls (CWs) are one of the targets for external stressors. Juvenile P. omorika trees were treated either with 21 day-high doses UV-B or with 7 day- UV-C in open-top chambers. Using spectroscopic and biochemical techniques, it was shown that the response to UV radiation includes numerous modifications in needle CW structure: relative content of xylan, xyloglucan, lignin and cellulose decreased; cellulose crystallinity changed; yield of lignin monomers with stronger connection of C[dbnd]C in side chain with the ring increased; re-distribution of inter- and intra-polymer H-bonds occurred. The recovery was mediated by an increase in the activities and changes in isoform profiles of CW bound covalent peroxidases (POD) and polyphenol oxidases (PO) (UV–B), and ionic POD and covalent PO (UV–C). A connection between activities of specific POD/PO isoforms and phenolic species (m- and p-coumaric acid, pinoresinol and cinnamic acid derivatives) was demonstrated, and supported by changes in the sRNA profile. In vivo fluorometry showed phenolics accumulation in needle epidermal CWs. These results imply transversal connections between polymers and changed mechanical properties of needle CW as a response to UV. The CW alterations enabled maintenance of physiological functions, as indicated by the preserved chlorophyll content and/or organization. The current study provides evidence that in conifers, needle CW response to both UV-B and UV-C includes biochemical modifications and structural remodeling. © 2021 Elsevier Masson SAS",
journal = "Plant Physiology and Biochemistry",
title = "Cell wall response to UV radiation in needles of Picea omorika",
volume = "161",
pages = "176-190",
doi = "10.1016/j.plaphy.2021.02.007"
}
Mitrović, A. Lj., Simonović-Radosavljević, J., Prokopijević, M., Spasojević, D., Kovačević, J., Prodanović, O., Todorović, B., Matović, B., Stanković, M., Maksimović, V., Mutavdžić, D., Skočić, M., Pešić, M., Prokić, L.,& Radotić, K. (2021). Cell wall response to UV radiation in needles of Picea omorika.
Plant Physiology and Biochemistry, 161, 176-190.
https://doi.org/10.1016/j.plaphy.2021.02.007
Mitrović AL, Simonović-Radosavljević J, Prokopijević M, Spasojević D, Kovačević J, Prodanović O, Todorović B, Matović B, Stanković M, Maksimović V, Mutavdžić D, Skočić M, Pešić M, Prokić L, Radotić K. Cell wall response to UV radiation in needles of Picea omorika. Plant Physiology and Biochemistry. 2021;161:176-190
Mitrović Aleksandra Lj., Simonović-Radosavljević Jasna, Prokopijević Miloš, Spasojević Dragica, Kovačević Jovana, Prodanović Olivera, Todorović Bratislav, Matović Branko, Stanković Mira, Maksimović Vuk, Mutavdžić Dragosav, Skočić Miloš, Pešić Mirjana, Prokić Ljiljana, Radotić Ksenija, "Cell wall response to UV radiation in needles of Picea omorika" Plant Physiology and Biochemistry, 161 (2021):176-190,
https://doi.org/10.1016/j.plaphy.2021.02.007 .