TY  - JOUR
AU  - Mačvanin, Mirjana
AU  - Gluvić, Zoran
AU  - Radovanović, Jelena
AU  - Essack, Magbubah
AU  - Gao, Xin
AU  - Isenović, Esma R.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10774
AB  - Diabetes mellitus (DM) is on the rise, necessitating the development of novel therapeutic and preventive strategies to mitigate the disease’s debilitating effects. Diabetic cardiomyopathy (DCMP) is among the leading causes of morbidity and mortality in diabetic patients globally. DCMP manifests as cardiomyocyte hypertrophy, apoptosis, and myocardial interstitial fibrosis before progressing to heart failure. Evidence suggests that non-coding RNAs, such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), regulate diabetic cardiomyopathy-related processes such as insulin resistance, cardiomyocyte apoptosis and inflammation, emphasizing their heart-protective effects. This paper reviewed the literature data from animal and human studies on the non-trivial roles of miRNAs and lncRNAs in the context of DCMP in diabetes and demonstrated their future potential in DCMP treatment in diabetic patients.
T2  - Frontiers in Endocrinology
T1  - Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs
VL  - 14
DO  - 10.3389/fendo.2023.1124613
ER  - 

@article{
author = "Mačvanin, Mirjana and Gluvić, Zoran and Radovanović, Jelena and Essack, Magbubah and Gao, Xin and Isenović, Esma R.",
year = "2023",
abstract = "Diabetes mellitus (DM) is on the rise, necessitating the development of novel therapeutic and preventive strategies to mitigate the disease’s debilitating effects. Diabetic cardiomyopathy (DCMP) is among the leading causes of morbidity and mortality in diabetic patients globally. DCMP manifests as cardiomyocyte hypertrophy, apoptosis, and myocardial interstitial fibrosis before progressing to heart failure. Evidence suggests that non-coding RNAs, such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), regulate diabetic cardiomyopathy-related processes such as insulin resistance, cardiomyocyte apoptosis and inflammation, emphasizing their heart-protective effects. This paper reviewed the literature data from animal and human studies on the non-trivial roles of miRNAs and lncRNAs in the context of DCMP in diabetes and demonstrated their future potential in DCMP treatment in diabetic patients.",
journal = "Frontiers in Endocrinology",
title = "Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs",
volume = "14",
doi = "10.3389/fendo.2023.1124613"
}

Mačvanin, M., Gluvić, Z., Radovanović, J., Essack, M., Gao, X.,& Isenović, E. R.. (2023). Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs. in Frontiers in Endocrinology, 14.
https://doi.org/10.3389/fendo.2023.1124613

Mačvanin M, Gluvić Z, Radovanović J, Essack M, Gao X, Isenović ER. Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs. in Frontiers in Endocrinology. 2023;14.
doi:10.3389/fendo.2023.1124613 .

Mačvanin, Mirjana, Gluvić, Zoran, Radovanović, Jelena, Essack, Magbubah, Gao, Xin, Isenović, Esma R., "Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs" in Frontiers in Endocrinology, 14 (2023),
https://doi.org/10.3389/fendo.2023.1124613 . .