TY  - JOUR
AU  - Tsotakos, T.
AU  - Tsoukalas, C.
AU  - Patsis, G.
AU  - Panagiotopoulou, A.
AU  - Nikolić, Nadežda S.
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
AU  - Raptopoulou, C. P.
AU  - Terzis, A.
AU  - Papagiannopoulou, D.
AU  - Pelecanou, M.
AU  - Papadopoulos, M.
AU  - Pirmettis, Ioannis
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4546
AB  - Two rhenium(I) tricarbonyl complexes with the tridentate monoanionic NSO ligands, 4-(benzimidazol-2-yl)-3-thiabutanoic acid (complex 3) and [1-(11-carboxyundecanyl)-4-(benzimidazol-2-yl)]-3-thiabutanoic acid (complex 4) were synthesized and characterized by spectroscopic methods and elemental analysis. X-ray crystallographic analysis of complex 3 revealed a distorted octahedral geometry around rhenium defined by the three facially bound CO groups and the NSO donor atom set of the tridentate ligand. The analogous technetium-99m complexes (complexes 5 and 6) were also prepared quantitatively by reaction of the NSO ligands with the fac-[Tc-99m(H2O)(3)(CO)(3)](+) synthon and their identity was established by chromatographic comparison to their rhenium congeners. Biodistribution in mice of complex 6 bearing the fatty acid chain showed significant heart uptake (6.26 +/- 0.79% ID/g p.i.) at 1 min accompanied, however, with a heart: blood ratio below 1. (C) 2011 Elsevier B. V. All rights reserved.
T2  - Inorganica Chimica Acta
T1  - Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m)
VL  - 377
IS  - 1
SP  - 62
EP  - 68
DO  - 10.1016/j.ica.2011.07.035
ER  - 

@article{
author = "Tsotakos, T. and Tsoukalas, C. and Patsis, G. and Panagiotopoulou, A. and Nikolić, Nadežda S. and Janković, Drina and Đokić, Divna Đ. and Raptopoulou, C. P. and Terzis, A. and Papagiannopoulou, D. and Pelecanou, M. and Papadopoulos, M. and Pirmettis, Ioannis",
year = "2011",
abstract = "Two rhenium(I) tricarbonyl complexes with the tridentate monoanionic NSO ligands, 4-(benzimidazol-2-yl)-3-thiabutanoic acid (complex 3) and [1-(11-carboxyundecanyl)-4-(benzimidazol-2-yl)]-3-thiabutanoic acid (complex 4) were synthesized and characterized by spectroscopic methods and elemental analysis. X-ray crystallographic analysis of complex 3 revealed a distorted octahedral geometry around rhenium defined by the three facially bound CO groups and the NSO donor atom set of the tridentate ligand. The analogous technetium-99m complexes (complexes 5 and 6) were also prepared quantitatively by reaction of the NSO ligands with the fac-[Tc-99m(H2O)(3)(CO)(3)](+) synthon and their identity was established by chromatographic comparison to their rhenium congeners. Biodistribution in mice of complex 6 bearing the fatty acid chain showed significant heart uptake (6.26 +/- 0.79% ID/g p.i.) at 1 min accompanied, however, with a heart: blood ratio below 1. (C) 2011 Elsevier B. V. All rights reserved.",
journal = "Inorganica Chimica Acta",
title = "Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m)",
volume = "377",
number = "1",
pages = "62-68",
doi = "10.1016/j.ica.2011.07.035"
}

Tsotakos, T., Tsoukalas, C., Patsis, G., Panagiotopoulou, A., Nikolić, N. S., Janković, D., Đokić, D. Đ., Raptopoulou, C. P., Terzis, A., Papagiannopoulou, D., Pelecanou, M., Papadopoulos, M.,& Pirmettis, I.. (2011). Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m). in Inorganica Chimica Acta, 377(1), 62-68.
https://doi.org/10.1016/j.ica.2011.07.035

Tsotakos T, Tsoukalas C, Patsis G, Panagiotopoulou A, Nikolić NS, Janković D, Đokić DĐ, Raptopoulou CP, Terzis A, Papagiannopoulou D, Pelecanou M, Papadopoulos M, Pirmettis I. Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m). in Inorganica Chimica Acta. 2011;377(1):62-68.
doi:10.1016/j.ica.2011.07.035 .

Tsotakos, T., Tsoukalas, C., Patsis, G., Panagiotopoulou, A., Nikolić, Nadežda S., Janković, Drina, Đokić, Divna Đ., Raptopoulou, C. P., Terzis, A., Papagiannopoulou, D., Pelecanou, M., Papadopoulos, M., Pirmettis, Ioannis, "Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m)" in Inorganica Chimica Acta, 377, no. 1 (2011):62-68,
https://doi.org/10.1016/j.ica.2011.07.035 . .