Serbian Government [Research Grant TR23040]

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Serbian Government [Research Grant TR23040]

Authors

Publications

The importance of population susceptibility to air pollution: gene candidate approach

Stanković, A.; Đurđević, V.; Kolaković, Ana; Stojković, Lj.; Živković, M.

(NILU - Norwegian Institute for Air Research, 2009)

TY  - CONF
AU  - Stanković, A.
AU  - Đurđević, V.
AU  - Kolaković, Ana
AU  - Stojković, Lj.
AU  - Živković, M.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12699
AB  - The effects of environmental exposures might be transmitted to cellular level through mechanisms that could vary between individuals. Gene polymorphism in GSTM1/GSTT1, both deletions in the gene, showed the significant influence in genetic association studies of air pollution. In order to analyze the association of GSTT1/GSTM1 polymorphism with respiratory and cardiovascular disease in regard to air- pollution, for the first time we detected the presence of GSTM1/GSTT1 deletion in two different environmental risk factors' populations, Belgrade and Obrenovac. The groups consisted of 71 (Belgrade)/89 (Obrenovac) participants. Genotyping was performed by multiplex PCR. The frequencies of “null” genotypes for GSTM1/GSTT1 were not significantly different between the two investigated groups (47.89%/44.94%, 15.49%/17.98%, respectively). In conclusion, the frequencies of detected “null” genotypes in investigated two population subsets of Serbian origin was similar and in range with the frequencies in other Caucasian populations.
PB  - NILU - Norwegian Institute for Air Research
C3  - 2nd International WeBIOPATR Workshop : "Particulate Matter-Research and Management" : Proceedings
T1  - The importance of population susceptibility to air pollution: gene candidate approach
SP  - 38
EP  - 42
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12699
ER  - 
@conference{
author = "Stanković, A. and Đurđević, V. and Kolaković, Ana and Stojković, Lj. and Živković, M.",
year = "2009",
abstract = "The effects of environmental exposures might be transmitted to cellular level through mechanisms that could vary between individuals. Gene polymorphism in GSTM1/GSTT1, both deletions in the gene, showed the significant influence in genetic association studies of air pollution. In order to analyze the association of GSTT1/GSTM1 polymorphism with respiratory and cardiovascular disease in regard to air- pollution, for the first time we detected the presence of GSTM1/GSTT1 deletion in two different environmental risk factors' populations, Belgrade and Obrenovac. The groups consisted of 71 (Belgrade)/89 (Obrenovac) participants. Genotyping was performed by multiplex PCR. The frequencies of “null” genotypes for GSTM1/GSTT1 were not significantly different between the two investigated groups (47.89%/44.94%, 15.49%/17.98%, respectively). In conclusion, the frequencies of detected “null” genotypes in investigated two population subsets of Serbian origin was similar and in range with the frequencies in other Caucasian populations.",
publisher = "NILU - Norwegian Institute for Air Research",
journal = "2nd International WeBIOPATR Workshop : "Particulate Matter-Research and Management" : Proceedings",
title = "The importance of population susceptibility to air pollution: gene candidate approach",
pages = "38-42",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12699"
}
Stanković, A., Đurđević, V., Kolaković, A., Stojković, Lj.,& Živković, M.. (2009). The importance of population susceptibility to air pollution: gene candidate approach. in 2nd International WeBIOPATR Workshop : "Particulate Matter-Research and Management" : Proceedings
NILU - Norwegian Institute for Air Research., 38-42.
https://hdl.handle.net/21.15107/rcub_vinar_12699
Stanković A, Đurđević V, Kolaković A, Stojković L, Živković M. The importance of population susceptibility to air pollution: gene candidate approach. in 2nd International WeBIOPATR Workshop : "Particulate Matter-Research and Management" : Proceedings. 2009;:38-42.
https://hdl.handle.net/21.15107/rcub_vinar_12699 .
Stanković, A., Đurđević, V., Kolaković, Ana, Stojković, Lj., Živković, M., "The importance of population susceptibility to air pollution: gene candidate approach" in 2nd International WeBIOPATR Workshop : "Particulate Matter-Research and Management" : Proceedings (2009):38-42,
https://hdl.handle.net/21.15107/rcub_vinar_12699 .