TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Marković, Zoran M.
AU  - Budimir, Milica
AU  - Zdravković, Nemanja M.
AU  - Trišić, Dijana 
AU  - Bugárová, Nikol
AU  - Danko, Martin
AU  - Kozyrovska, Natalia O.
AU  - Špitalský, Zdeno
AU  - Kleinová, Angela
AU  - Kuzman, Sanja
AU  - Pavlović, Vladimir B.
AU  - Todorović-Marković, Biljana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9566
AB  - Bacterial infection and their resistance to known antibiotics delays wound healing. In this study, nanochitosan dots (nChiD) produced by gamma irradiation have been encapsulated in bacterial cellulose (BC) polymer matrix to study the antibacterial potentials of these nanocomposites and their possible usage in wound healing treatment (scratch assay). Detailed analyses show that nChiDs have disc-like shape and average diameter in the range of 40 to 60 nm depending of the applied dose. All nChiDs as well as BC-nChiD nanocomposites emit green photoluminescence independently on the excitation wavelengths. The new designed nanocomposites do not have a cytotoxic effect; antioxidant analysis shows their moderate radical scavenging activity whereas antibacterial properties show significant growth inhibition of strains mostly found in difficult-to-heal wounds. The obtained results confirm that new designed BC-nChiD nanocomposites might be potential agent in wound healing treatment. © 2021 Elsevier B.V.
T2  - Materials Science and Engineering: C
T1  - Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment
VL  - 122
SP  - 111925
DO  - 10.1016/j.msec.2021.111925
ER  - 

@article{
author = "Zmejkoski, Danica and Marković, Zoran M. and Budimir, Milica and Zdravković, Nemanja M. and Trišić, Dijana  and Bugárová, Nikol and Danko, Martin and Kozyrovska, Natalia O. and Špitalský, Zdeno and Kleinová, Angela and Kuzman, Sanja and Pavlović, Vladimir B. and Todorović-Marković, Biljana",
year = "2021",
abstract = "Bacterial infection and their resistance to known antibiotics delays wound healing. In this study, nanochitosan dots (nChiD) produced by gamma irradiation have been encapsulated in bacterial cellulose (BC) polymer matrix to study the antibacterial potentials of these nanocomposites and their possible usage in wound healing treatment (scratch assay). Detailed analyses show that nChiDs have disc-like shape and average diameter in the range of 40 to 60 nm depending of the applied dose. All nChiDs as well as BC-nChiD nanocomposites emit green photoluminescence independently on the excitation wavelengths. The new designed nanocomposites do not have a cytotoxic effect; antioxidant analysis shows their moderate radical scavenging activity whereas antibacterial properties show significant growth inhibition of strains mostly found in difficult-to-heal wounds. The obtained results confirm that new designed BC-nChiD nanocomposites might be potential agent in wound healing treatment. © 2021 Elsevier B.V.",
journal = "Materials Science and Engineering: C",
title = "Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment",
volume = "122",
pages = "111925",
doi = "10.1016/j.msec.2021.111925"
}

Zmejkoski, D., Marković, Z. M., Budimir, M., Zdravković, N. M., Trišić, D., Bugárová, N., Danko, M., Kozyrovska, N. O., Špitalský, Z., Kleinová, A., Kuzman, S., Pavlović, V. B.,& Todorović-Marković, B.. (2021). Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment. in Materials Science and Engineering: C, 122, 111925.
https://doi.org/10.1016/j.msec.2021.111925

Zmejkoski D, Marković ZM, Budimir M, Zdravković NM, Trišić D, Bugárová N, Danko M, Kozyrovska NO, Špitalský Z, Kleinová A, Kuzman S, Pavlović VB, Todorović-Marković B. Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment. in Materials Science and Engineering: C. 2021;122:111925.
doi:10.1016/j.msec.2021.111925 .

Zmejkoski, Danica, Marković, Zoran M., Budimir, Milica, Zdravković, Nemanja M., Trišić, Dijana , Bugárová, Nikol, Danko, Martin, Kozyrovska, Natalia O., Špitalský, Zdeno, Kleinová, Angela, Kuzman, Sanja, Pavlović, Vladimir B., Todorović-Marković, Biljana, "Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment" in Materials Science and Engineering: C, 122 (2021):111925,
https://doi.org/10.1016/j.msec.2021.111925 . .