TY  - JOUR
AU  - Radovanović, Jelena
AU  - Antonijević, Biljana
AU  - Kolarević, Stoimir
AU  - Milutinović-Smiljanić, Sanja
AU  - Mandić, Jelena
AU  - Vuković-Gačić, Branka
AU  - Bulat, Zorica
AU  - Ćurčić, Marijana
AU  - Kračun-Kolarević, Margareta
AU  - Sunjog, Karolina
AU  - Kostić-Vuković, Jovana
AU  - Jovanović Marić, Jovana
AU  - Antonijević-Miljaković, Evica
AU  - Đukić-Ćosić, Danijela
AU  - Buha-Đorđević, Aleksandra
AU  - Javorac, Dragana
AU  - Baralić, Katarina
AU  - Mandinić, Zoran
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9778
AB  - The aims of this study were to: (i) examine the toxic effects of sodium fluoride (NaF) in blood, liver, spleen, and brain cells of Wistar rats after the subacute exposure; (ii) explore the potential protective properties of selenium (Se) against fluoride toxicity after the simultaneous administration. Twenty male Wistar rats, eight weeks old, weighing approximately 140–190 g, were divided into four experimental groups (n = 5) as follows: I control-tap water; II NaF 150 ppm; III NaF 150 ppm and Se 1.5 mg/L; IV Se 1.5 mg/L, and had available water with solutions ad libitum for 28 days. DNA damage detected by comet assay was confirmed in the liver, spleen, and brain cells, but not in blood. Selenium supplementation together with NaF decreased DNA damage in liver and spleen cells. According to the histological findings, no changes were observed in spleen and brain tissues after NaF administration. Unlike the observed Se protective effect on the DNA level, no significant reduction of liver tissue injury was observed after the NaF and Se treatment, resulting in mild inflammation. Data of this study suggest that DNA damage after NaF subacute exposure at moderately high concentration was reduced in liver and spleen cells due to Se supplementation, but a similar change was not seen in the brain.
T2  - Chemosphere
T1  - Genotoxicity of fluoride subacute exposure in rats and selenium intervention
VL  - 266
DO  - 10.1016/j.chemosphere.2020.128978
ER  - 

@article{
author = "Radovanović, Jelena and Antonijević, Biljana and Kolarević, Stoimir and Milutinović-Smiljanić, Sanja and Mandić, Jelena and Vuković-Gačić, Branka and Bulat, Zorica and Ćurčić, Marijana and Kračun-Kolarević, Margareta and Sunjog, Karolina and Kostić-Vuković, Jovana and Jovanović Marić, Jovana and Antonijević-Miljaković, Evica and Đukić-Ćosić, Danijela and Buha-Đorđević, Aleksandra and Javorac, Dragana and Baralić, Katarina and Mandinić, Zoran",
year = "2021",
abstract = "The aims of this study were to: (i) examine the toxic effects of sodium fluoride (NaF) in blood, liver, spleen, and brain cells of Wistar rats after the subacute exposure; (ii) explore the potential protective properties of selenium (Se) against fluoride toxicity after the simultaneous administration. Twenty male Wistar rats, eight weeks old, weighing approximately 140–190 g, were divided into four experimental groups (n = 5) as follows: I control-tap water; II NaF 150 ppm; III NaF 150 ppm and Se 1.5 mg/L; IV Se 1.5 mg/L, and had available water with solutions ad libitum for 28 days. DNA damage detected by comet assay was confirmed in the liver, spleen, and brain cells, but not in blood. Selenium supplementation together with NaF decreased DNA damage in liver and spleen cells. According to the histological findings, no changes were observed in spleen and brain tissues after NaF administration. Unlike the observed Se protective effect on the DNA level, no significant reduction of liver tissue injury was observed after the NaF and Se treatment, resulting in mild inflammation. Data of this study suggest that DNA damage after NaF subacute exposure at moderately high concentration was reduced in liver and spleen cells due to Se supplementation, but a similar change was not seen in the brain.",
journal = "Chemosphere",
title = "Genotoxicity of fluoride subacute exposure in rats and selenium intervention",
volume = "266",
doi = "10.1016/j.chemosphere.2020.128978"
}

Radovanović, J., Antonijević, B., Kolarević, S., Milutinović-Smiljanić, S., Mandić, J., Vuković-Gačić, B., Bulat, Z., Ćurčić, M., Kračun-Kolarević, M., Sunjog, K., Kostić-Vuković, J., Jovanović Marić, J., Antonijević-Miljaković, E., Đukić-Ćosić, D., Buha-Đorđević, A., Javorac, D., Baralić, K.,& Mandinić, Z.. (2021). Genotoxicity of fluoride subacute exposure in rats and selenium intervention. in Chemosphere, 266.
https://doi.org/10.1016/j.chemosphere.2020.128978

Radovanović J, Antonijević B, Kolarević S, Milutinović-Smiljanić S, Mandić J, Vuković-Gačić B, Bulat Z, Ćurčić M, Kračun-Kolarević M, Sunjog K, Kostić-Vuković J, Jovanović Marić J, Antonijević-Miljaković E, Đukić-Ćosić D, Buha-Đorđević A, Javorac D, Baralić K, Mandinić Z. Genotoxicity of fluoride subacute exposure in rats and selenium intervention. in Chemosphere. 2021;266.
doi:10.1016/j.chemosphere.2020.128978 .

Radovanović, Jelena, Antonijević, Biljana, Kolarević, Stoimir, Milutinović-Smiljanić, Sanja, Mandić, Jelena, Vuković-Gačić, Branka, Bulat, Zorica, Ćurčić, Marijana, Kračun-Kolarević, Margareta, Sunjog, Karolina, Kostić-Vuković, Jovana, Jovanović Marić, Jovana, Antonijević-Miljaković, Evica, Đukić-Ćosić, Danijela, Buha-Đorđević, Aleksandra, Javorac, Dragana, Baralić, Katarina, Mandinić, Zoran, "Genotoxicity of fluoride subacute exposure in rats and selenium intervention" in Chemosphere, 266 (2021),
https://doi.org/10.1016/j.chemosphere.2020.128978 . .

TY  - JOUR
AU  - Šuluburic, Adam
AU  - Milanovic, Svetlana
AU  - Vranješ-Đurić, Sanja
AU  - Jovanović, Ivan B.
AU  - Barna, Tomislav
AU  - Stojić, Milica
AU  - Fratric, Natalija
AU  - Szenci, Otto
AU  - Gvozdic, Dragan
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1757
AB  - Early embryonic development may be negatively affected by insufficient progesterone (P4) production. Therefore, the aim of our study was to increase P4 by gonadotropin-releasing hormone (GnRH) and/or human chorionic gonadotropin (hCG) treatments after inducing oestrus by prostaglandin (PG) treatment. Lactating Simmental dairy cows (n = 110), between 1 to 5 lactations, with an average milk production of 6,500 l/305 days, at 40-80 days postpartum were used and grouped as follows: (1) PG + GnRH treatment at AI (GnRH group), (2) PG + hCG treatment at day 7 after AI (hCG group), (3) PG + GnRH at AI + hCG treatment at day 7 after AI (GnRH/hCG group), and (4) spontaneous oestrus (C: control group). All animals were double inseminated (at the time of oestrus detection and 12 +/- 2 h thereafter). Blood serum and milk samples were collected at the day of observed oestrus (day 0), and 14, 21 and 28 days after AI. Serum P4 was determined using a commercial radioimmunoassay (RIA) test (INEP, Zemun), and milk P4 was determined using enzyme-linked immunoassay (ELISA) test (NIV Novi Sad). Pregnancy status was confirmed by ultrasonography between days 28 and 35 after AI. Differences of serum or milk P4 medians, pregnancy (and calving) rate were determined using Dunns Multiple Comparison Tests and Z test, respectively. Serum P4 medians were significantly higher at days 14, 21 and 28 after AI in the hCG-treated animals, indicating increased luteal activity, with a similar tendency in whole milk P4 values. Treatment with hCG during the early luteal phase significantly contributed to the maintenance of gestation at days 28-35 after AI, and also increased the calving rate in Simmental dairy cows.
T2  - Acta Veterinaria Hungarica
T1  - Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase
VL  - 65
IS  - 3
SP  - 446
EP  - 458
DO  - 10.1556/004.2017.042
ER  - 

@article{
author = "Šuluburic, Adam and Milanovic, Svetlana and Vranješ-Đurić, Sanja and Jovanović, Ivan B. and Barna, Tomislav and Stojić, Milica and Fratric, Natalija and Szenci, Otto and Gvozdic, Dragan",
year = "2017",
abstract = "Early embryonic development may be negatively affected by insufficient progesterone (P4) production. Therefore, the aim of our study was to increase P4 by gonadotropin-releasing hormone (GnRH) and/or human chorionic gonadotropin (hCG) treatments after inducing oestrus by prostaglandin (PG) treatment. Lactating Simmental dairy cows (n = 110), between 1 to 5 lactations, with an average milk production of 6,500 l/305 days, at 40-80 days postpartum were used and grouped as follows: (1) PG + GnRH treatment at AI (GnRH group), (2) PG + hCG treatment at day 7 after AI (hCG group), (3) PG + GnRH at AI + hCG treatment at day 7 after AI (GnRH/hCG group), and (4) spontaneous oestrus (C: control group). All animals were double inseminated (at the time of oestrus detection and 12 +/- 2 h thereafter). Blood serum and milk samples were collected at the day of observed oestrus (day 0), and 14, 21 and 28 days after AI. Serum P4 was determined using a commercial radioimmunoassay (RIA) test (INEP, Zemun), and milk P4 was determined using enzyme-linked immunoassay (ELISA) test (NIV Novi Sad). Pregnancy status was confirmed by ultrasonography between days 28 and 35 after AI. Differences of serum or milk P4 medians, pregnancy (and calving) rate were determined using Dunns Multiple Comparison Tests and Z test, respectively. Serum P4 medians were significantly higher at days 14, 21 and 28 after AI in the hCG-treated animals, indicating increased luteal activity, with a similar tendency in whole milk P4 values. Treatment with hCG during the early luteal phase significantly contributed to the maintenance of gestation at days 28-35 after AI, and also increased the calving rate in Simmental dairy cows.",
journal = "Acta Veterinaria Hungarica",
title = "Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase",
volume = "65",
number = "3",
pages = "446-458",
doi = "10.1556/004.2017.042"
}

Šuluburic, A., Milanovic, S., Vranješ-Đurić, S., Jovanović, I. B., Barna, T., Stojić, M., Fratric, N., Szenci, O.,& Gvozdic, D.. (2017). Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase. in Acta Veterinaria Hungarica, 65(3), 446-458.
https://doi.org/10.1556/004.2017.042

Šuluburic A, Milanovic S, Vranješ-Đurić S, Jovanović IB, Barna T, Stojić M, Fratric N, Szenci O, Gvozdic D. Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase. in Acta Veterinaria Hungarica. 2017;65(3):446-458.
doi:10.1556/004.2017.042 .

Šuluburic, Adam, Milanovic, Svetlana, Vranješ-Đurić, Sanja, Jovanović, Ivan B., Barna, Tomislav, Stojić, Milica, Fratric, Natalija, Szenci, Otto, Gvozdic, Dragan, "Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase" in Acta Veterinaria Hungarica, 65, no. 3 (2017):446-458,
https://doi.org/10.1556/004.2017.042 . .