TY  - JOUR
AU  - Stojiljković, Vesna
AU  - Todorović, Ana
AU  - Pejić, Snežana
AU  - Kasapović, Jelena
AU  - Saičić, Zorica S.
AU  - Radlovic, Nedeljko
AU  - Pajović, Snežana B.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3836
AB  - Objective: To explain the role of oxidative stress in the pathology of celiac disease. Design and methods: The activities of antioxidant enzymes and the levels of glutathione and lipid hydroperoxides were measured in the samples of small intestinal biopsies from 39 children with different forms of the disease and in 19 control subjects. Results: The activities of analyzed enzymes varied significantly between the examined groups. An increase in the activities of superoxide dismutase was observed in patients with active and silent celiac disease, while the activities of glutathione peroxidase and glutathione reductase and the glutathione content were significantly reduced. The level of lipid hydroperoxides was significantly elevated in these groups. Conclusions: Oxidative stress is an important factor in the pathogenesis of celiac disease. The antioxidant capacity of celiac patients is significantly reduced, mostly by a depletion of glutathione. Natural antioxidants and appropriate dietary supplements could be important complements to the classic therapy of celiac disease. (C) 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
T2  - Clinical Biochemistry
T1  - Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease
VL  - 42
IS  - 13-14
SP  - 1431
EP  - 1437
DO  - 10.1016/j.clinbiochem.2009.06.009
ER  - 

@article{
author = "Stojiljković, Vesna and Todorović, Ana and Pejić, Snežana and Kasapović, Jelena and Saičić, Zorica S. and Radlovic, Nedeljko and Pajović, Snežana B.",
year = "2009",
abstract = "Objective: To explain the role of oxidative stress in the pathology of celiac disease. Design and methods: The activities of antioxidant enzymes and the levels of glutathione and lipid hydroperoxides were measured in the samples of small intestinal biopsies from 39 children with different forms of the disease and in 19 control subjects. Results: The activities of analyzed enzymes varied significantly between the examined groups. An increase in the activities of superoxide dismutase was observed in patients with active and silent celiac disease, while the activities of glutathione peroxidase and glutathione reductase and the glutathione content were significantly reduced. The level of lipid hydroperoxides was significantly elevated in these groups. Conclusions: Oxidative stress is an important factor in the pathogenesis of celiac disease. The antioxidant capacity of celiac patients is significantly reduced, mostly by a depletion of glutathione. Natural antioxidants and appropriate dietary supplements could be important complements to the classic therapy of celiac disease. (C) 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.",
journal = "Clinical Biochemistry",
title = "Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease",
volume = "42",
number = "13-14",
pages = "1431-1437",
doi = "10.1016/j.clinbiochem.2009.06.009"
}

Stojiljković, V., Todorović, A., Pejić, S., Kasapović, J., Saičić, Z. S., Radlovic, N.,& Pajović, S. B.. (2009). Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease. in Clinical Biochemistry, 42(13-14), 1431-1437.
https://doi.org/10.1016/j.clinbiochem.2009.06.009

Stojiljković V, Todorović A, Pejić S, Kasapović J, Saičić ZS, Radlovic N, Pajović SB. Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease. in Clinical Biochemistry. 2009;42(13-14):1431-1437.
doi:10.1016/j.clinbiochem.2009.06.009 .

Stojiljković, Vesna, Todorović, Ana, Pejić, Snežana, Kasapović, Jelena, Saičić, Zorica S., Radlovic, Nedeljko, Pajović, Snežana B., "Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease" in Clinical Biochemistry, 42, no. 13-14 (2009):1431-1437,
https://doi.org/10.1016/j.clinbiochem.2009.06.009 . .