TY  - JOUR
AU  - Lazić, Vesna M.
AU  - Živković, Ljiljana
AU  - Sredojević, Dušan
AU  - Fernandes,  Margarida M.
AU  - Lanceros-Mendez,  Senentxu
AU  - Ahrenkiel, Scott Phillip
AU  - Nedeljković, Jovan
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9613
AB  - Cerium dioxide (CeO2) finds applications in areas such as corrosion protection, solar cells, or catalysis, finding increasing applications in biomedicine. This work reports on surface-modified CeO2 particles in order to tune their applicability in the biomedical field. Stable aqueous CeO2 sol, consisting of 3-4 nm in size crystallites, was synthesized using forced hydrolysis. The coordination of catecholate-type of ligands (catechol, caffeic acid, tiron, and dopamine) to the surface-Ce atoms is followed with the appearance of absorption in the visible spectral range as a consequence of interfacial charge-transfer complex formation. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The synthesized samples were characterized by X-ray diffraction analysis, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. The ζ-potential measurements indicated that the stability of CeO2 sol is preserved upon surface modification. The pristine CeO2 nanoparticles (NPs) are nontoxic against pre-osteoblast cells in the entire studied concentration range (up to 1.5 mM). Hybrid CeO2 NPs, capped with dopamine or caffeic acid, display toxic behavior for concentrations ≥0.17 and 1.5 mM, respectively. On the other hand, surface-modified CeO2 NPs with catechol and tiron promote the proliferation of pre-osteoblast cells. Copyright © 2020 American Chemical Society.
T2  - Langmuir
T1  - Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands
VL  - 36
IS  - 33
SP  - 9738
EP  - 9746
DO  - 10.1021/acs.langmuir.0c01163
ER  - 

@article{
author = "Lazić, Vesna M. and Živković, Ljiljana and Sredojević, Dušan and Fernandes,  Margarida M. and Lanceros-Mendez,  Senentxu and Ahrenkiel, Scott Phillip and Nedeljković, Jovan",
year = "2020",
abstract = "Cerium dioxide (CeO2) finds applications in areas such as corrosion protection, solar cells, or catalysis, finding increasing applications in biomedicine. This work reports on surface-modified CeO2 particles in order to tune their applicability in the biomedical field. Stable aqueous CeO2 sol, consisting of 3-4 nm in size crystallites, was synthesized using forced hydrolysis. The coordination of catecholate-type of ligands (catechol, caffeic acid, tiron, and dopamine) to the surface-Ce atoms is followed with the appearance of absorption in the visible spectral range as a consequence of interfacial charge-transfer complex formation. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The synthesized samples were characterized by X-ray diffraction analysis, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. The ζ-potential measurements indicated that the stability of CeO2 sol is preserved upon surface modification. The pristine CeO2 nanoparticles (NPs) are nontoxic against pre-osteoblast cells in the entire studied concentration range (up to 1.5 mM). Hybrid CeO2 NPs, capped with dopamine or caffeic acid, display toxic behavior for concentrations ≥0.17 and 1.5 mM, respectively. On the other hand, surface-modified CeO2 NPs with catechol and tiron promote the proliferation of pre-osteoblast cells. Copyright © 2020 American Chemical Society.",
journal = "Langmuir",
title = "Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands",
volume = "36",
number = "33",
pages = "9738-9746",
doi = "10.1021/acs.langmuir.0c01163"
}

Lazić, V. M., Živković, L., Sredojević, D., Fernandes, M. M., Lanceros-Mendez, S., Ahrenkiel, S. P.,& Nedeljković, J.. (2020). Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands. in Langmuir, 36(33), 9738-9746.
https://doi.org/10.1021/acs.langmuir.0c01163

Lazić VM, Živković L, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković J. Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands. in Langmuir. 2020;36(33):9738-9746.
doi:10.1021/acs.langmuir.0c01163 .

Lazić, Vesna M., Živković, Ljiljana, Sredojević, Dušan, Fernandes,  Margarida M., Lanceros-Mendez,  Senentxu, Ahrenkiel, Scott Phillip, Nedeljković, Jovan, "Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands" in Langmuir, 36, no. 33 (2020):9738-9746,
https://doi.org/10.1021/acs.langmuir.0c01163 . .