TY  - JOUR
AU  - El Barbary, Magdy A.
AU  - Saad, Alaa Eldin M.
AU  - Attia, Fadia M.
AU  - Mandour, Magda I.
AU  - Haidara, Mohamed A.
AU  - Dallak, Mohammad M.
AU  - Isenović, Esma R.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3932
AB  - A total of 30 patients with chronic hepatitis C (HCV) thrombocytopenia (TP) and 20 healthy controls were studied. Both groups were subjected to complete medical history, clinical examination in addition to assessment of hepatitis markers: level of thrombopoietin (Tpo), Geimsa-stained bone marrow smears, and in vitro short-term megakaryocytic progenitors culture (CFU-MK). Serum Tpo level was significantly elevated in patients with TP HCV. Short-term CFU-MK showed an evident depression in the colony-forming unit-megakaryocyte (CFU-meg). There is a positive correlation between the number of CFU-meg and the platelet count and between serum Tpo level and prothrombin time, transaminase, albumin, and the Child Pugh score of liver disease; a negative correlation between serum Tpo level and the number of CFU-meg and between serum Tpo level and the platelet count. Thus, the level of Tpo could be an indicator of intact functional response of the hepatocytes.
T2  - Angiology
T1  - Thrombocytopenia in Patients With Chronic Hepatitis C: A Possible Role of HCV on Platelet Progenitor Cell Maturation
VL  - 61
IS  - 3
SP  - 304
EP  - 313
DO  - 10.1177/0003319709343178
ER  - 

@article{
author = "El Barbary, Magdy A. and Saad, Alaa Eldin M. and Attia, Fadia M. and Mandour, Magda I. and Haidara, Mohamed A. and Dallak, Mohammad M. and Isenović, Esma R.",
year = "2010",
abstract = "A total of 30 patients with chronic hepatitis C (HCV) thrombocytopenia (TP) and 20 healthy controls were studied. Both groups were subjected to complete medical history, clinical examination in addition to assessment of hepatitis markers: level of thrombopoietin (Tpo), Geimsa-stained bone marrow smears, and in vitro short-term megakaryocytic progenitors culture (CFU-MK). Serum Tpo level was significantly elevated in patients with TP HCV. Short-term CFU-MK showed an evident depression in the colony-forming unit-megakaryocyte (CFU-meg). There is a positive correlation between the number of CFU-meg and the platelet count and between serum Tpo level and prothrombin time, transaminase, albumin, and the Child Pugh score of liver disease; a negative correlation between serum Tpo level and the number of CFU-meg and between serum Tpo level and the platelet count. Thus, the level of Tpo could be an indicator of intact functional response of the hepatocytes.",
journal = "Angiology",
title = "Thrombocytopenia in Patients With Chronic Hepatitis C: A Possible Role of HCV on Platelet Progenitor Cell Maturation",
volume = "61",
number = "3",
pages = "304-313",
doi = "10.1177/0003319709343178"
}

El Barbary, M. A., Saad, A. E. M., Attia, F. M., Mandour, M. I., Haidara, M. A., Dallak, M. M.,& Isenović, E. R.. (2010). Thrombocytopenia in Patients With Chronic Hepatitis C: A Possible Role of HCV on Platelet Progenitor Cell Maturation. in Angiology, 61(3), 304-313.
https://doi.org/10.1177/0003319709343178

El Barbary MA, Saad AEM, Attia FM, Mandour MI, Haidara MA, Dallak MM, Isenović ER. Thrombocytopenia in Patients With Chronic Hepatitis C: A Possible Role of HCV on Platelet Progenitor Cell Maturation. in Angiology. 2010;61(3):304-313.
doi:10.1177/0003319709343178 .

El Barbary, Magdy A., Saad, Alaa Eldin M., Attia, Fadia M., Mandour, Magda I., Haidara, Mohamed A., Dallak, Mohammad M., Isenović, Esma R., "Thrombocytopenia in Patients With Chronic Hepatitis C: A Possible Role of HCV on Platelet Progenitor Cell Maturation" in Angiology, 61, no. 3 (2010):304-313,
https://doi.org/10.1177/0003319709343178 . .

TY  - JOUR
AU  - Sudar, Emina
AU  - Dobutović, Branislava
AU  - Milosavljević, Tijana
AU  - Putniković, Biljana
AU  - Gluvić, Zoran
AU  - Isenović, Esma R.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3804
AB  - Insulin (INS) and beta-estradiol (E(2)) have vascular effects partially through stimulation of protein kinase B (Akt) phosphorylation. Employing adult rat cardiomyocytes (ARC), the effects of acute (15 min) stimulation with INS (10 mIU/ml) and prolonged (2 hours and 24 hours) stimulation with E(2) alone or in combination, were assessed with respect to protein levels of Akt. Exposure to INS for 15 minutes enhanced Akt Ser(473) phosphorylation. The combined treatment had a greater effect on Akt phosphorylation then the effect of INS alone. The results suggest that INS and E(2) may interact through Akt in regulating metabolic processes.
T2  - Acta Chimica Slovenica
T1  - Interactive Effects of Insulin and beta-Estradiol on Protein Kinase B Phosphorylation in Adult Rat Cardiomyocytes
VL  - 56
IS  - 3
SP  - 723
EP  - 728
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3804
ER  - 

@article{
author = "Sudar, Emina and Dobutović, Branislava and Milosavljević, Tijana and Putniković, Biljana and Gluvić, Zoran and Isenović, Esma R.",
year = "2009",
abstract = "Insulin (INS) and beta-estradiol (E(2)) have vascular effects partially through stimulation of protein kinase B (Akt) phosphorylation. Employing adult rat cardiomyocytes (ARC), the effects of acute (15 min) stimulation with INS (10 mIU/ml) and prolonged (2 hours and 24 hours) stimulation with E(2) alone or in combination, were assessed with respect to protein levels of Akt. Exposure to INS for 15 minutes enhanced Akt Ser(473) phosphorylation. The combined treatment had a greater effect on Akt phosphorylation then the effect of INS alone. The results suggest that INS and E(2) may interact through Akt in regulating metabolic processes.",
journal = "Acta Chimica Slovenica",
title = "Interactive Effects of Insulin and beta-Estradiol on Protein Kinase B Phosphorylation in Adult Rat Cardiomyocytes",
volume = "56",
number = "3",
pages = "723-728",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3804"
}

Sudar, E., Dobutović, B., Milosavljević, T., Putniković, B., Gluvić, Z.,& Isenović, E. R.. (2009). Interactive Effects of Insulin and beta-Estradiol on Protein Kinase B Phosphorylation in Adult Rat Cardiomyocytes. in Acta Chimica Slovenica, 56(3), 723-728.
https://hdl.handle.net/21.15107/rcub_vinar_3804

Sudar E, Dobutović B, Milosavljević T, Putniković B, Gluvić Z, Isenović ER. Interactive Effects of Insulin and beta-Estradiol on Protein Kinase B Phosphorylation in Adult Rat Cardiomyocytes. in Acta Chimica Slovenica. 2009;56(3):723-728.
https://hdl.handle.net/21.15107/rcub_vinar_3804 .

Sudar, Emina, Dobutović, Branislava, Milosavljević, Tijana, Putniković, Biljana, Gluvić, Zoran, Isenović, Esma R., "Interactive Effects of Insulin and beta-Estradiol on Protein Kinase B Phosphorylation in Adult Rat Cardiomyocytes" in Acta Chimica Slovenica, 56, no. 3 (2009):723-728,
https://hdl.handle.net/21.15107/rcub_vinar_3804 .