TY  - JOUR
AU  - Mehmeti, Eda
AU  - Stanković, Dalibor M.
AU  - Kalcher, Kurt
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1892
AB  - In this work a new electrochemical method will be presented for the determination of enalapril in pharmaceutical tablets using unmodified screen printed electrode (SPE). The studies were done using amperommetric detection. Enalapril provides well defined, ovalshape oxidation peak at +1.05 V (vs. Ag/AgCl, 3.0 M KCl) in Britton-Robinson buffer solution (BRBS) at pH 5.0. After optimization of the experimental conditions, the influence of most common interferent compounds was tested. Under optimized experimental conditions, the signals were linearly proportional to the concentration of enalapril in the range from 2.5 to 90 mu M with a detection limit of 0.9 mu M. Repeatability of ten replicate measurements of 5 mu M enalapril was estimated to be 1.5%. Proposed method was successfully applied for the determination of the total amount of enalapril content in pharmaceutical preparations. Nevertheless, proposed method could be beneficial for the quick quantifications of enalapril in drugs using unmodified SPE electrode without any further treatment.
T2  - Analytical and Bioanalytical Electrochemistry
T1  - Determination of Enalapril in Pharmaceuticals using Electrochemical Sensing with Amperometric Detection
VL  - 9
IS  - 8
SP  - 1000
EP  - 1007
UR  - https://hdl.handle.net/21.15107/rcub_vinar_1892
ER  - 

@article{
author = "Mehmeti, Eda and Stanković, Dalibor M. and Kalcher, Kurt",
year = "2017",
abstract = "In this work a new electrochemical method will be presented for the determination of enalapril in pharmaceutical tablets using unmodified screen printed electrode (SPE). The studies were done using amperommetric detection. Enalapril provides well defined, ovalshape oxidation peak at +1.05 V (vs. Ag/AgCl, 3.0 M KCl) in Britton-Robinson buffer solution (BRBS) at pH 5.0. After optimization of the experimental conditions, the influence of most common interferent compounds was tested. Under optimized experimental conditions, the signals were linearly proportional to the concentration of enalapril in the range from 2.5 to 90 mu M with a detection limit of 0.9 mu M. Repeatability of ten replicate measurements of 5 mu M enalapril was estimated to be 1.5%. Proposed method was successfully applied for the determination of the total amount of enalapril content in pharmaceutical preparations. Nevertheless, proposed method could be beneficial for the quick quantifications of enalapril in drugs using unmodified SPE electrode without any further treatment.",
journal = "Analytical and Bioanalytical Electrochemistry",
title = "Determination of Enalapril in Pharmaceuticals using Electrochemical Sensing with Amperometric Detection",
volume = "9",
number = "8",
pages = "1000-1007",
url = "https://hdl.handle.net/21.15107/rcub_vinar_1892"
}

Mehmeti, E., Stanković, D. M.,& Kalcher, K.. (2017). Determination of Enalapril in Pharmaceuticals using Electrochemical Sensing with Amperometric Detection. in Analytical and Bioanalytical Electrochemistry, 9(8), 1000-1007.
https://hdl.handle.net/21.15107/rcub_vinar_1892

Mehmeti E, Stanković DM, Kalcher K. Determination of Enalapril in Pharmaceuticals using Electrochemical Sensing with Amperometric Detection. in Analytical and Bioanalytical Electrochemistry. 2017;9(8):1000-1007.
https://hdl.handle.net/21.15107/rcub_vinar_1892 .

Mehmeti, Eda, Stanković, Dalibor M., Kalcher, Kurt, "Determination of Enalapril in Pharmaceuticals using Electrochemical Sensing with Amperometric Detection" in Analytical and Bioanalytical Electrochemistry, 9, no. 8 (2017):1000-1007,
https://hdl.handle.net/21.15107/rcub_vinar_1892 .