Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou

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Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (en)
Синтеза функционалних материјала са контролисаном структуром на молекуларном и нано нивоу (sr)
Sinteza funkcionalnih materijala sa kontrolisanom strukturom na molekularnom i nano nivou (sr_RS)
Authors

Publications

Dense fine-grained biphasic calcium phosphate (BCP) bioceramics designed by two-step sintering

Lukić, M.; Stojanović, Zoran S.; Škapin, Srečo Davor; Macek-Krzmanc, M.; Mitrić, Miodrag; Marković, Smilja; Uskoković, Dragan

(2011)

TY  - JOUR
AU  - Lukić, M.
AU  - Stojanović, Zoran S.
AU  - Škapin, Srečo Davor
AU  - Macek-Krzmanc, M.
AU  - Mitrić, Miodrag
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4155
AB  - In this study, dense fine-grained biphasic calcium phosphate bioceramics were designed via the two-step sintering method The starting powder was nanosized calcium-deficient hydroxyapatite, whose phase composition, average particle size and morphology were characterized by XRD, FTIR, Raman spectroscopy, laser diffraction and FE-SEM The phase transformations of the initial powder during heating up to 1200 degrees C were examined using TG/DSC At first, conventional sintering was performed and the recorded shrinkage/densification data were used to find out the appropriate experimental conditions for two step sintering The obtained results show that two step sintering yields BCP ceramics consisting of hydroxyapatite and beta-TCP with lull dense, homogeneous structure with average grain size of 375 nm Furthermore BCP ceramics obtained by the two-step sintering method exhibit improved mechanical properties, compared to conventionally sintered BCP (C) 2010 Elsevier Ltd All rights reserved
T2  - Journal of the European Ceramic Society
T1  - Dense fine-grained biphasic calcium phosphate (BCP) bioceramics designed by two-step sintering
VL  - 31
IS  - 1-2
SP  - 19
EP  - 27
DO  - 10.1016/j.jeurceramsoc.2010.09.006
ER  - 
@article{
author = "Lukić, M. and Stojanović, Zoran S. and Škapin, Srečo Davor and Macek-Krzmanc, M. and Mitrić, Miodrag and Marković, Smilja and Uskoković, Dragan",
year = "2011",
abstract = "In this study, dense fine-grained biphasic calcium phosphate bioceramics were designed via the two-step sintering method The starting powder was nanosized calcium-deficient hydroxyapatite, whose phase composition, average particle size and morphology were characterized by XRD, FTIR, Raman spectroscopy, laser diffraction and FE-SEM The phase transformations of the initial powder during heating up to 1200 degrees C were examined using TG/DSC At first, conventional sintering was performed and the recorded shrinkage/densification data were used to find out the appropriate experimental conditions for two step sintering The obtained results show that two step sintering yields BCP ceramics consisting of hydroxyapatite and beta-TCP with lull dense, homogeneous structure with average grain size of 375 nm Furthermore BCP ceramics obtained by the two-step sintering method exhibit improved mechanical properties, compared to conventionally sintered BCP (C) 2010 Elsevier Ltd All rights reserved",
journal = "Journal of the European Ceramic Society",
title = "Dense fine-grained biphasic calcium phosphate (BCP) bioceramics designed by two-step sintering",
volume = "31",
number = "1-2",
pages = "19-27",
doi = "10.1016/j.jeurceramsoc.2010.09.006"
}
Lukić, M., Stojanović, Z. S., Škapin, S. D., Macek-Krzmanc, M., Mitrić, M., Marković, S.,& Uskoković, D.. (2011). Dense fine-grained biphasic calcium phosphate (BCP) bioceramics designed by two-step sintering. in Journal of the European Ceramic Society, 31(1-2), 19-27.
https://doi.org/10.1016/j.jeurceramsoc.2010.09.006
Lukić M, Stojanović ZS, Škapin SD, Macek-Krzmanc M, Mitrić M, Marković S, Uskoković D. Dense fine-grained biphasic calcium phosphate (BCP) bioceramics designed by two-step sintering. in Journal of the European Ceramic Society. 2011;31(1-2):19-27.
doi:10.1016/j.jeurceramsoc.2010.09.006 .
Lukić, M., Stojanović, Zoran S., Škapin, Srečo Davor, Macek-Krzmanc, M., Mitrić, Miodrag, Marković, Smilja, Uskoković, Dragan, "Dense fine-grained biphasic calcium phosphate (BCP) bioceramics designed by two-step sintering" in Journal of the European Ceramic Society, 31, no. 1-2 (2011):19-27,
https://doi.org/10.1016/j.jeurceramsoc.2010.09.006 . .
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67

Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery

Vukomanovic, Marija; Škapin, Srečo Davor; Jančar, Boštjan; Maksin, Tatjana N.; Ignjatović, Nenad L.; Uskokovic, Vuk; Uskoković, Dragan

(2011)

TY  - JOUR
AU  - Vukomanovic, Marija
AU  - Škapin, Srečo Davor
AU  - Jančar, Boštjan
AU  - Maksin, Tatjana N.
AU  - Ignjatović, Nenad L.
AU  - Uskokovic, Vuk
AU  - Uskoković, Dragan
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4188
AB  - Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces. B: Biointerfaces
T1  - Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery
VL  - 82
IS  - 2
SP  - 404
EP  - 413
DO  - 10.1016/j.colsurfb.2010.09.011
ER  - 
@article{
author = "Vukomanovic, Marija and Škapin, Srečo Davor and Jančar, Boštjan and Maksin, Tatjana N. and Ignjatović, Nenad L. and Uskokovic, Vuk and Uskoković, Dragan",
year = "2011",
abstract = "Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces. B: Biointerfaces",
title = "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery",
volume = "82",
number = "2",
pages = "404-413",
doi = "10.1016/j.colsurfb.2010.09.011"
}
Vukomanovic, M., Škapin, S. D., Jančar, B., Maksin, T. N., Ignjatović, N. L., Uskokovic, V.,& Uskoković, D.. (2011). Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces. B: Biointerfaces, 82(2), 404-413.
https://doi.org/10.1016/j.colsurfb.2010.09.011
Vukomanovic M, Škapin SD, Jančar B, Maksin TN, Ignjatović NL, Uskokovic V, Uskoković D. Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces. B: Biointerfaces. 2011;82(2):404-413.
doi:10.1016/j.colsurfb.2010.09.011 .
Vukomanovic, Marija, Škapin, Srečo Davor, Jančar, Boštjan, Maksin, Tatjana N., Ignjatović, Nenad L., Uskokovic, Vuk, Uskoković, Dragan, "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery" in Colloids and Surfaces. B: Biointerfaces, 82, no. 2 (2011):404-413,
https://doi.org/10.1016/j.colsurfb.2010.09.011 . .
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Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite

Vukomanovic, Marija; Mitrić, Miodrag; Škapin, Srečo Davor; Zagar, Ema; Plavec, Janez; Ignjatović, Nenad L.; Uskoković, Dragan

(2010)

TY  - JOUR
AU  - Vukomanovic, Marija
AU  - Mitrić, Miodrag
AU  - Škapin, Srečo Davor
AU  - Zagar, Ema
AU  - Plavec, Janez
AU  - Ignjatović, Nenad L.
AU  - Uskoković, Dragan
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3943
AB  - In this work poly(D,L-lactide-co-glycolide) (PLGA) and a poly(D,L-lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) composite processed in an ultrasonic field at higher (25 degrees C) and lower (8 degrees C) temperatures were studied with respect to the molecular properties of the obtained materials. The processing of the PLGA and the PLGA/HAp composite in an ultrasonic field resulted in a change of molar mass averages of the polymer/polymeric part of these materials, while an amorphous structure and a 50:50 lactide-to-glycolide co-monomer ratio were preserved without the formation of crystalline oligomers. However, mobility of polymeric chains obtained after ultrasonic processing was lower indicating ordering the structure of polymeric chains as a result of processing. Additionally, it was observed that the mobility of the PLGA macromolecules was lower within the composite in comparison with the mobility of the chains within the PLGA alone in the case when both were obtained after ultrasonic processing. This was a consequence of the structure formation through the interactions between the PLGA and the HAp. Based on these results different degradation rate of PLGA in composite can be expected, which is important in the application of this material for the controlled drug delivery of medicaments. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Ultrasonics Sonochemistry
T1  - Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite
VL  - 17
IS  - 5
SP  - 902
EP  - 908
DO  - 10.1016/j.ultsonch.2010.01.007
ER  - 
@article{
author = "Vukomanovic, Marija and Mitrić, Miodrag and Škapin, Srečo Davor and Zagar, Ema and Plavec, Janez and Ignjatović, Nenad L. and Uskoković, Dragan",
year = "2010",
abstract = "In this work poly(D,L-lactide-co-glycolide) (PLGA) and a poly(D,L-lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) composite processed in an ultrasonic field at higher (25 degrees C) and lower (8 degrees C) temperatures were studied with respect to the molecular properties of the obtained materials. The processing of the PLGA and the PLGA/HAp composite in an ultrasonic field resulted in a change of molar mass averages of the polymer/polymeric part of these materials, while an amorphous structure and a 50:50 lactide-to-glycolide co-monomer ratio were preserved without the formation of crystalline oligomers. However, mobility of polymeric chains obtained after ultrasonic processing was lower indicating ordering the structure of polymeric chains as a result of processing. Additionally, it was observed that the mobility of the PLGA macromolecules was lower within the composite in comparison with the mobility of the chains within the PLGA alone in the case when both were obtained after ultrasonic processing. This was a consequence of the structure formation through the interactions between the PLGA and the HAp. Based on these results different degradation rate of PLGA in composite can be expected, which is important in the application of this material for the controlled drug delivery of medicaments. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Ultrasonics Sonochemistry",
title = "Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite",
volume = "17",
number = "5",
pages = "902-908",
doi = "10.1016/j.ultsonch.2010.01.007"
}
Vukomanovic, M., Mitrić, M., Škapin, S. D., Zagar, E., Plavec, J., Ignjatović, N. L.,& Uskoković, D.. (2010). Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite. in Ultrasonics Sonochemistry, 17(5), 902-908.
https://doi.org/10.1016/j.ultsonch.2010.01.007
Vukomanovic M, Mitrić M, Škapin SD, Zagar E, Plavec J, Ignjatović NL, Uskoković D. Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite. in Ultrasonics Sonochemistry. 2010;17(5):902-908.
doi:10.1016/j.ultsonch.2010.01.007 .
Vukomanovic, Marija, Mitrić, Miodrag, Škapin, Srečo Davor, Zagar, Ema, Plavec, Janez, Ignjatović, Nenad L., Uskoković, Dragan, "Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite" in Ultrasonics Sonochemistry, 17, no. 5 (2010):902-908,
https://doi.org/10.1016/j.ultsonch.2010.01.007 . .
8
6
8

An innovative, quick and convenient labeling method for the investigation of pharmacological behavior and the metabolism of poly(DL-lactide-co-glycolide) nanospheres

Stevanović, Magdalena; Maksin, Tatjana N.; Petkovic, Jana; Filipic, Metka; Uskoković, Dragan

(2009)

TY  - JOUR
AU  - Stevanović, Magdalena
AU  - Maksin, Tatjana N.
AU  - Petkovic, Jana
AU  - Filipic, Metka
AU  - Uskoković, Dragan
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3755
AB  - Nanoparticles of poly(DL-lactide-co-glycolide) (PLGA) in the size range 90-150 nm were produced using the physicochemical method with solvent/non-solvent systems. The encapsulation of the ascorbic acid in the polymer matrix was performed by homogenization of the water and organic phases. In vitro degradation and release tests of PLGA nanoparticles with and without encapsulated ascorbic acid were studied for more than 60 days in PBS and it has been determined that PLGA completely degrades within this period, fully releasing all encapsulated ascorbic acid. The cytotoxicity of PLGA and PLGA/ascorbic acid 85/15% nanoparticles was examined with human hepatoma cell lines (HepG2 ECACC), in vitro. The obtained results indicate that neither PLGA nanospheres nor PLGA/ascorbic acid 85/15% nanoparticles significantly affected the viability of the HepG2 cells. The investigation of the distribution and pharmacokinetics of PLGA is crucial for the effective prediction of host responses to PLGA in particular applications. Thus we present a method of labeling PLGA nanospheres and PLGA/ascorbic acid 85/15 wt% nanoparticles by (99m)Tc which binds outside, leaving the cage intact. This enables a quick and convenient investigation of the pharmacological behavior and metabolism of PLGA. The biodistribution of (99m)Tc-labeled PLGA particles with and without encapsulated ascorbic acid after different periods of time of their installation into rats was examined. PLGA nanospheres with encapsulated ascorbic acid exhibit prolonged blood circulation accompanied by time-dependent reduction in the lungs, liver and spleen, and addition in the kidney, stomach and intestine. The samples were characterized by x-ray diffraction, scanning electron microscopy, stereological analysis, transmission electron microscopy, ultraviolet spectroscopy and instant thin layer chromatography.
T2  - Nanotechnology
T1  - An innovative, quick and convenient labeling method for the investigation of pharmacological behavior and the metabolism of poly(DL-lactide-co-glycolide) nanospheres
VL  - 20
IS  - 33
DO  - 10.1088/0957-4484/20/33/335102
ER  - 
@article{
author = "Stevanović, Magdalena and Maksin, Tatjana N. and Petkovic, Jana and Filipic, Metka and Uskoković, Dragan",
year = "2009",
abstract = "Nanoparticles of poly(DL-lactide-co-glycolide) (PLGA) in the size range 90-150 nm were produced using the physicochemical method with solvent/non-solvent systems. The encapsulation of the ascorbic acid in the polymer matrix was performed by homogenization of the water and organic phases. In vitro degradation and release tests of PLGA nanoparticles with and without encapsulated ascorbic acid were studied for more than 60 days in PBS and it has been determined that PLGA completely degrades within this period, fully releasing all encapsulated ascorbic acid. The cytotoxicity of PLGA and PLGA/ascorbic acid 85/15% nanoparticles was examined with human hepatoma cell lines (HepG2 ECACC), in vitro. The obtained results indicate that neither PLGA nanospheres nor PLGA/ascorbic acid 85/15% nanoparticles significantly affected the viability of the HepG2 cells. The investigation of the distribution and pharmacokinetics of PLGA is crucial for the effective prediction of host responses to PLGA in particular applications. Thus we present a method of labeling PLGA nanospheres and PLGA/ascorbic acid 85/15 wt% nanoparticles by (99m)Tc which binds outside, leaving the cage intact. This enables a quick and convenient investigation of the pharmacological behavior and metabolism of PLGA. The biodistribution of (99m)Tc-labeled PLGA particles with and without encapsulated ascorbic acid after different periods of time of their installation into rats was examined. PLGA nanospheres with encapsulated ascorbic acid exhibit prolonged blood circulation accompanied by time-dependent reduction in the lungs, liver and spleen, and addition in the kidney, stomach and intestine. The samples were characterized by x-ray diffraction, scanning electron microscopy, stereological analysis, transmission electron microscopy, ultraviolet spectroscopy and instant thin layer chromatography.",
journal = "Nanotechnology",
title = "An innovative, quick and convenient labeling method for the investigation of pharmacological behavior and the metabolism of poly(DL-lactide-co-glycolide) nanospheres",
volume = "20",
number = "33",
doi = "10.1088/0957-4484/20/33/335102"
}
Stevanović, M., Maksin, T. N., Petkovic, J., Filipic, M.,& Uskoković, D.. (2009). An innovative, quick and convenient labeling method for the investigation of pharmacological behavior and the metabolism of poly(DL-lactide-co-glycolide) nanospheres. in Nanotechnology, 20(33).
https://doi.org/10.1088/0957-4484/20/33/335102
Stevanović M, Maksin TN, Petkovic J, Filipic M, Uskoković D. An innovative, quick and convenient labeling method for the investigation of pharmacological behavior and the metabolism of poly(DL-lactide-co-glycolide) nanospheres. in Nanotechnology. 2009;20(33).
doi:10.1088/0957-4484/20/33/335102 .
Stevanović, Magdalena, Maksin, Tatjana N., Petkovic, Jana, Filipic, Metka, Uskoković, Dragan, "An innovative, quick and convenient labeling method for the investigation of pharmacological behavior and the metabolism of poly(DL-lactide-co-glycolide) nanospheres" in Nanotechnology, 20, no. 33 (2009),
https://doi.org/10.1088/0957-4484/20/33/335102 . .
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Controlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiation

Jevtic, M.; Radulovic, A.; Ignjatović, Nenad L.; Mitrić, Miodrag; Uskoković, Dragan

(2009)

TY  - JOUR
AU  - Jevtic, M.
AU  - Radulovic, A.
AU  - Ignjatović, Nenad L.
AU  - Mitrić, Miodrag
AU  - Uskoković, Dragan
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3597
AB  - An ultrasound field was applied to obtain PLGA/HAp biocomposite nanospheres. Formulation of PLGA/HAp, composite revealed significant dependence of the morphology of the obtained composite on synthesis parameters, like the intensity of applied ultrasonic field, polymeric and ceramic parts wt.% ratio in the composite, temperature of the medium, type of surfactant, and the sequence of steps in the formation of PLGA/HAp. Optimal parameters for the formation of PLGA/HAp included a lower content of the ceramic phase (PLGA/HAp = 90: 10), higher power of ultrasonic field (P = 142.4 W), lower temperature of the medium during ultrasonic treatment (T = 8 degrees C), dilute solution of PVP as surfactant and dispersion of hydroxyapatite in polymer solution in order to achieve required homogeneity before the formulation of the composite. The morphology of PLGA/HAp particles synthesized under these conditions was highly regular: sphere-like, with particles of very small dimensions (150-320 nm), highly uniform particle size distribution and characteristic planar spatial self-organization. These characteristics indicate significant improvements in PLGA/HAp composite resulting from ultrasonic method. (C) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
T2  - Acta Biomaterialia
T1  - Controlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiation
VL  - 5
IS  - 1
SP  - 208
EP  - 218
DO  - 10.1016/j.actbio.2008.07.026
ER  - 
@article{
author = "Jevtic, M. and Radulovic, A. and Ignjatović, Nenad L. and Mitrić, Miodrag and Uskoković, Dragan",
year = "2009",
abstract = "An ultrasound field was applied to obtain PLGA/HAp biocomposite nanospheres. Formulation of PLGA/HAp, composite revealed significant dependence of the morphology of the obtained composite on synthesis parameters, like the intensity of applied ultrasonic field, polymeric and ceramic parts wt.% ratio in the composite, temperature of the medium, type of surfactant, and the sequence of steps in the formation of PLGA/HAp. Optimal parameters for the formation of PLGA/HAp included a lower content of the ceramic phase (PLGA/HAp = 90: 10), higher power of ultrasonic field (P = 142.4 W), lower temperature of the medium during ultrasonic treatment (T = 8 degrees C), dilute solution of PVP as surfactant and dispersion of hydroxyapatite in polymer solution in order to achieve required homogeneity before the formulation of the composite. The morphology of PLGA/HAp particles synthesized under these conditions was highly regular: sphere-like, with particles of very small dimensions (150-320 nm), highly uniform particle size distribution and characteristic planar spatial self-organization. These characteristics indicate significant improvements in PLGA/HAp composite resulting from ultrasonic method. (C) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.",
journal = "Acta Biomaterialia",
title = "Controlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiation",
volume = "5",
number = "1",
pages = "208-218",
doi = "10.1016/j.actbio.2008.07.026"
}
Jevtic, M., Radulovic, A., Ignjatović, N. L., Mitrić, M.,& Uskoković, D.. (2009). Controlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiation. in Acta Biomaterialia, 5(1), 208-218.
https://doi.org/10.1016/j.actbio.2008.07.026
Jevtic M, Radulovic A, Ignjatović NL, Mitrić M, Uskoković D. Controlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiation. in Acta Biomaterialia. 2009;5(1):208-218.
doi:10.1016/j.actbio.2008.07.026 .
Jevtic, M., Radulovic, A., Ignjatović, Nenad L., Mitrić, Miodrag, Uskoković, Dragan, "Controlled assembly of Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres under ultrasonic irradiation" in Acta Biomaterialia, 5, no. 1 (2009):208-218,
https://doi.org/10.1016/j.actbio.2008.07.026 . .
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50

Dielectric and ferroelectric properties of BaTi1-xSnxO3 multilayered ceramics

Marković, Smilja; Mitrić, Miodrag; Jovalekić, Čedomir; Miljkovic, M.

(2007)

TY  - CONF
AU  - Marković, Smilja
AU  - Mitrić, Miodrag
AU  - Jovalekić, Čedomir
AU  - Miljkovic, M.
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6688
AB  - Multilayered BaTi1-xSnxO3 (BTS) ceramics with different Ti/Sn ratios were produced by pressing and sintering at 1420 degrees C for 2 hours. X-ray diffractometry, scanning electron microscopy and energy dispersive spectroscopy were used for structural, microstructural and elemental analysis, respectively. The dielectric and ferroelectric behavior of sintered samples was studied, too. It is found that in ingredient materials, with increasing Sri content, the tetragonality decreases; Curie temperature moves towards room temperature, while the maximum of the dielectric constant increases, and also, they becomes less hysteretic. It is noticed that multilayered BTS ceramics with different Ti/Sn contents have a broad transition temperature and show a relatively high dielectric constant in a wide temperature range. It is shown that dielectric properties of these materials may be modified by a combination of different BTS powders as well as layers number.
C3  - Materials Science Forum
T1  - Dielectric and ferroelectric properties of BaTi1-xSnxO3 multilayered ceramics
VL  - 555
SP  - 249
EP  - +
DO  - 10.4028/www.scientific.net/MSF.555.249
ER  - 
@conference{
author = "Marković, Smilja and Mitrić, Miodrag and Jovalekić, Čedomir and Miljkovic, M.",
year = "2007",
abstract = "Multilayered BaTi1-xSnxO3 (BTS) ceramics with different Ti/Sn ratios were produced by pressing and sintering at 1420 degrees C for 2 hours. X-ray diffractometry, scanning electron microscopy and energy dispersive spectroscopy were used for structural, microstructural and elemental analysis, respectively. The dielectric and ferroelectric behavior of sintered samples was studied, too. It is found that in ingredient materials, with increasing Sri content, the tetragonality decreases; Curie temperature moves towards room temperature, while the maximum of the dielectric constant increases, and also, they becomes less hysteretic. It is noticed that multilayered BTS ceramics with different Ti/Sn contents have a broad transition temperature and show a relatively high dielectric constant in a wide temperature range. It is shown that dielectric properties of these materials may be modified by a combination of different BTS powders as well as layers number.",
journal = "Materials Science Forum",
title = "Dielectric and ferroelectric properties of BaTi1-xSnxO3 multilayered ceramics",
volume = "555",
pages = "249-+",
doi = "10.4028/www.scientific.net/MSF.555.249"
}
Marković, S., Mitrić, M., Jovalekić, Č.,& Miljkovic, M.. (2007). Dielectric and ferroelectric properties of BaTi1-xSnxO3 multilayered ceramics. in Materials Science Forum, 555, 249-+.
https://doi.org/10.4028/www.scientific.net/MSF.555.249
Marković S, Mitrić M, Jovalekić Č, Miljkovic M. Dielectric and ferroelectric properties of BaTi1-xSnxO3 multilayered ceramics. in Materials Science Forum. 2007;555:249-+.
doi:10.4028/www.scientific.net/MSF.555.249 .
Marković, Smilja, Mitrić, Miodrag, Jovalekić, Čedomir, Miljkovic, M., "Dielectric and ferroelectric properties of BaTi1-xSnxO3 multilayered ceramics" in Materials Science Forum, 555 (2007):249-+,
https://doi.org/10.4028/www.scientific.net/MSF.555.249 . .
9
7

Comparison between different LiFePO4 synthesis routes

Jugović, Dragana; Cvjetićanin, Nikola; Mitrić, Miodrag; Mentus, Slavko V.

(2007)

TY  - CONF
AU  - Jugović, Dragana
AU  - Cvjetićanin, Nikola
AU  - Mitrić, Miodrag
AU  - Mentus, Slavko V.
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6685
AB  - Olivine-type lithium iron phosphate (LiFePO4) powders were synthesized applying three different methods: solid state reaction at high temperature, ultrasonic spray pyrolysis, and sonochemical treatment. The samples were characterized by X-ray powder diffraction (XRPD). Particle morphologies of the obtained powders were determined by scanning electron microscopy (SEM). It was found that structural and microstructural parameters of this material were strongly dependent on the synthesis conditions. We present here the results obtained upon optimization of each procedure for designing this cathode material.
C3  - Materials Science Forum
T1  - Comparison between different LiFePO4 synthesis routes
VL  - 555
SP  - 225
EP  - +
DO  - 10.4028/www.scientific.net/MSF.555.225
ER  - 
@conference{
author = "Jugović, Dragana and Cvjetićanin, Nikola and Mitrić, Miodrag and Mentus, Slavko V.",
year = "2007",
abstract = "Olivine-type lithium iron phosphate (LiFePO4) powders were synthesized applying three different methods: solid state reaction at high temperature, ultrasonic spray pyrolysis, and sonochemical treatment. The samples were characterized by X-ray powder diffraction (XRPD). Particle morphologies of the obtained powders were determined by scanning electron microscopy (SEM). It was found that structural and microstructural parameters of this material were strongly dependent on the synthesis conditions. We present here the results obtained upon optimization of each procedure for designing this cathode material.",
journal = "Materials Science Forum",
title = "Comparison between different LiFePO4 synthesis routes",
volume = "555",
pages = "225-+",
doi = "10.4028/www.scientific.net/MSF.555.225"
}
Jugović, D., Cvjetićanin, N., Mitrić, M.,& Mentus, S. V.. (2007). Comparison between different LiFePO4 synthesis routes. in Materials Science Forum, 555, 225-+.
https://doi.org/10.4028/www.scientific.net/MSF.555.225
Jugović D, Cvjetićanin N, Mitrić M, Mentus SV. Comparison between different LiFePO4 synthesis routes. in Materials Science Forum. 2007;555:225-+.
doi:10.4028/www.scientific.net/MSF.555.225 .
Jugović, Dragana, Cvjetićanin, Nikola, Mitrić, Miodrag, Mentus, Slavko V., "Comparison between different LiFePO4 synthesis routes" in Materials Science Forum, 555 (2007):225-+,
https://doi.org/10.4028/www.scientific.net/MSF.555.225 . .
4
5

Sonochemical Preparation of Hydroxyapatite/Poly (lactide-co-glycolyde) Composite

Jevtić, Marija; Mitrić, Miodrag; Ignjatović, Nenad L.; Uskoković, Dragan

(2007)

TY  - CONF
AU  - Jevtić, Marija
AU  - Mitrić, Miodrag
AU  - Ignjatović, Nenad L.
AU  - Uskoković, Dragan
PY  - 2007
UR  - http://dais.sanu.ac.rs/123456789/318
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7396
AB  - Poster presented at the 9th Conference of the Yugoslav Materials Research Society - YUCOMAT 2007, Herceg Novi, Crna Gora, September 10-14, 2007.
T1  - Sonochemical Preparation of Hydroxyapatite/Poly (lactide-co-glycolyde) Composite
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7396
ER  - 
@conference{
author = "Jevtić, Marija and Mitrić, Miodrag and Ignjatović, Nenad L. and Uskoković, Dragan",
year = "2007",
abstract = "Poster presented at the 9th Conference of the Yugoslav Materials Research Society - YUCOMAT 2007, Herceg Novi, Crna Gora, September 10-14, 2007.",
title = "Sonochemical Preparation of Hydroxyapatite/Poly (lactide-co-glycolyde) Composite",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7396"
}
Jevtić, M., Mitrić, M., Ignjatović, N. L.,& Uskoković, D.. (2007). Sonochemical Preparation of Hydroxyapatite/Poly (lactide-co-glycolyde) Composite. .
https://hdl.handle.net/21.15107/rcub_vinar_7396
Jevtić M, Mitrić M, Ignjatović NL, Uskoković D. Sonochemical Preparation of Hydroxyapatite/Poly (lactide-co-glycolyde) Composite. 2007;.
https://hdl.handle.net/21.15107/rcub_vinar_7396 .
Jevtić, Marija, Mitrić, Miodrag, Ignjatović, Nenad L., Uskoković, Dragan, "Sonochemical Preparation of Hydroxyapatite/Poly (lactide-co-glycolyde) Composite" (2007),
https://hdl.handle.net/21.15107/rcub_vinar_7396 .

Ultrasound modifications of physical properties of BaTiO3 powders

Marković, Smilja; Kandić, Ljiljana; Mitrić, Miodrag; Starčević, Goran; Uskoković, Dragan

(Society of Physical Chemists of Serbia, 2006)

TY  - CONF
AU  - Marković, Smilja
AU  - Kandić, Ljiljana
AU  - Mitrić, Miodrag
AU  - Starčević, Goran
AU  - Uskoković, Dragan
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9453
AB  - The starting BaTiO3 powder was prepared by solid state reaction, and then modified by ultrasound into powders with different physical characteristics. The prepared barium titanate powders were characterized by X-ray powder diffraction (XRD), laser particle size analyzer, also, specific surface area and powders density were determined. The studies indicate that physical properties of BaTiO3 powders were changed by sonochemical treatment. However, tetragonal crystal structure was maintained. It is shown that sonochemical method can be used for easy modification of barium titanate powder characteristics.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
T1  - Ultrasound modifications of physical properties of BaTiO3 powders
SP  - 519
EP  - 521
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9453
ER  - 
@conference{
author = "Marković, Smilja and Kandić, Ljiljana and Mitrić, Miodrag and Starčević, Goran and Uskoković, Dragan",
year = "2006",
abstract = "The starting BaTiO3 powder was prepared by solid state reaction, and then modified by ultrasound into powders with different physical characteristics. The prepared barium titanate powders were characterized by X-ray powder diffraction (XRD), laser particle size analyzer, also, specific surface area and powders density were determined. The studies indicate that physical properties of BaTiO3 powders were changed by sonochemical treatment. However, tetragonal crystal structure was maintained. It is shown that sonochemical method can be used for easy modification of barium titanate powder characteristics.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry",
title = "Ultrasound modifications of physical properties of BaTiO3 powders",
pages = "519-521",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9453"
}
Marković, S., Kandić, L., Mitrić, M., Starčević, G.,& Uskoković, D.. (2006). Ultrasound modifications of physical properties of BaTiO3 powders. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 519-521.
https://hdl.handle.net/21.15107/rcub_vinar_9453
Marković S, Kandić L, Mitrić M, Starčević G, Uskoković D. Ultrasound modifications of physical properties of BaTiO3 powders. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry. 2006;:519-521.
https://hdl.handle.net/21.15107/rcub_vinar_9453 .
Marković, Smilja, Kandić, Ljiljana, Mitrić, Miodrag, Starčević, Goran, Uskoković, Dragan, "Ultrasound modifications of physical properties of BaTiO3 powders" in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry (2006):519-521,
https://hdl.handle.net/21.15107/rcub_vinar_9453 .

Preparation of composite material BCP/DLPLG with a different content of ceramic and polymer component

Stevanović, M.; Ignjatović, Nenad L.; Miličević, Dejan S.; Uskoković, Dragan

(Society of Physical Chemists of Serbia, 2006)

TY  - CONF
AU  - Stevanović, M.
AU  - Ignjatović, Nenad L.
AU  - Miličević, Dejan S.
AU  - Uskoković, Dragan
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9447
AB  - Using a new approach of synthesis, homogenisation of DLPLG polymer powder and BCP gel, BCP/DLPLG composite material has been obtained with morphological and structural characteristics making it potentially very suitable for practical application in certain fields of the reconstructive medicine. The composite material has been synthesised with different ratios of ceramics and polymer BCP/DLPLG; 65/35w/w, 10/90 w/w, 5/95 w/w and 2/98w/w. The samples were characterized by Differential Scanning Calorimetry (DSC) and Scanning Electron Microscopy (SEM).
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
T1  - Preparation of composite material BCP/DLPLG with a different content of ceramic and polymer component
SP  - 498
EP  - 500
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9447
ER  - 
@conference{
author = "Stevanović, M. and Ignjatović, Nenad L. and Miličević, Dejan S. and Uskoković, Dragan",
year = "2006",
abstract = "Using a new approach of synthesis, homogenisation of DLPLG polymer powder and BCP gel, BCP/DLPLG composite material has been obtained with morphological and structural characteristics making it potentially very suitable for practical application in certain fields of the reconstructive medicine. The composite material has been synthesised with different ratios of ceramics and polymer BCP/DLPLG; 65/35w/w, 10/90 w/w, 5/95 w/w and 2/98w/w. The samples were characterized by Differential Scanning Calorimetry (DSC) and Scanning Electron Microscopy (SEM).",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry",
title = "Preparation of composite material BCP/DLPLG with a different content of ceramic and polymer component",
pages = "498-500",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9447"
}
Stevanović, M., Ignjatović, N. L., Miličević, D. S.,& Uskoković, D.. (2006). Preparation of composite material BCP/DLPLG with a different content of ceramic and polymer component. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 498-500.
https://hdl.handle.net/21.15107/rcub_vinar_9447
Stevanović M, Ignjatović NL, Miličević DS, Uskoković D. Preparation of composite material BCP/DLPLG with a different content of ceramic and polymer component. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry. 2006;:498-500.
https://hdl.handle.net/21.15107/rcub_vinar_9447 .
Stevanović, M., Ignjatović, Nenad L., Miličević, Dejan S., Uskoković, Dragan, "Preparation of composite material BCP/DLPLG with a different content of ceramic and polymer component" in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry (2006):498-500,
https://hdl.handle.net/21.15107/rcub_vinar_9447 .

Sonochemical Synthesis of Hydroxyapatite Using Homogeneous Precipitation Agent- Urea

Jevtić, Marija; Mitrić, Miodrag; Ignjatović, Nenad L.; Uskoković, Dragan

(2006)

TY  - CONF
AU  - Jevtić, Marija
AU  - Mitrić, Miodrag
AU  - Ignjatović, Nenad L.
AU  - Uskoković, Dragan
PY  - 2006
UR  - http://dais.sanu.ac.rs/123456789/326
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7402
AB  - Poster presented at the 8th Conference of Yugoslav Materials Research Society – YUCOMAT 2006, Herceg Novi, Crna Gora, 4-8. septembar 2006.
T1  - Sonochemical Synthesis of Hydroxyapatite Using Homogeneous Precipitation Agent- Urea
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7402
ER  - 
@conference{
author = "Jevtić, Marija and Mitrić, Miodrag and Ignjatović, Nenad L. and Uskoković, Dragan",
year = "2006",
abstract = "Poster presented at the 8th Conference of Yugoslav Materials Research Society – YUCOMAT 2006, Herceg Novi, Crna Gora, 4-8. septembar 2006.",
title = "Sonochemical Synthesis of Hydroxyapatite Using Homogeneous Precipitation Agent- Urea",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7402"
}
Jevtić, M., Mitrić, M., Ignjatović, N. L.,& Uskoković, D.. (2006). Sonochemical Synthesis of Hydroxyapatite Using Homogeneous Precipitation Agent- Urea. .
https://hdl.handle.net/21.15107/rcub_vinar_7402
Jevtić M, Mitrić M, Ignjatović NL, Uskoković D. Sonochemical Synthesis of Hydroxyapatite Using Homogeneous Precipitation Agent- Urea. 2006;.
https://hdl.handle.net/21.15107/rcub_vinar_7402 .
Jevtić, Marija, Mitrić, Miodrag, Ignjatović, Nenad L., Uskoković, Dragan, "Sonochemical Synthesis of Hydroxyapatite Using Homogeneous Precipitation Agent- Urea" (2006),
https://hdl.handle.net/21.15107/rcub_vinar_7402 .

The formation and characterization of nanocrystalline phases by mechanical milling of biphasic calcium phosphate/poly-L-lactide biocomposite

Nikcevic, I.; Maravić, Dubravka S.; Ignjatović, Nenad L.; Mitrić, Miodrag; Makovec, Darko; Uskoković, Dragan

(2006)

TY  - JOUR
AU  - Nikcevic, I.
AU  - Maravić, Dubravka S.
AU  - Ignjatović, Nenad L.
AU  - Mitrić, Miodrag
AU  - Makovec, Darko
AU  - Uskoković, Dragan
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3156
AB  - Biphasic calcium phosphate/poly-L-lactide granules of 150-200 mu m sizes were subjected to high-energy mechanical milling in a planetary ball mill for up to 480 minutes. Characterization of the material obtained was carried out using X-ray diffraction (XRD), differential scanning calorimetry (DSC), environmentally scanning electronic microscopy (ESEM), transmission electron microscopy (TEM) and infrared spectroscopy (IR). These techniques confirmed that mechanical milling induced significant changes in the biocomposite structure and properties. The most significant changes are reduction of the HAp crystallites size from 99.8 to 26.7 nm and beta-TCP from 97.3 to 29.6, as well as crystallinity of PLLA phases. Homogeneous phase distribution (arrangement) is obtained by extending the duration of mechanical milling.
T2  - Materials Transactions. JIM / Japan Institute of Metals
T1  - The formation and characterization of nanocrystalline phases by mechanical milling of biphasic calcium phosphate/poly-L-lactide biocomposite
VL  - 47
IS  - 12
SP  - 2980
EP  - 2986
DO  - 10.2320/matertrans.47.2980
ER  - 
@article{
author = "Nikcevic, I. and Maravić, Dubravka S. and Ignjatović, Nenad L. and Mitrić, Miodrag and Makovec, Darko and Uskoković, Dragan",
year = "2006",
abstract = "Biphasic calcium phosphate/poly-L-lactide granules of 150-200 mu m sizes were subjected to high-energy mechanical milling in a planetary ball mill for up to 480 minutes. Characterization of the material obtained was carried out using X-ray diffraction (XRD), differential scanning calorimetry (DSC), environmentally scanning electronic microscopy (ESEM), transmission electron microscopy (TEM) and infrared spectroscopy (IR). These techniques confirmed that mechanical milling induced significant changes in the biocomposite structure and properties. The most significant changes are reduction of the HAp crystallites size from 99.8 to 26.7 nm and beta-TCP from 97.3 to 29.6, as well as crystallinity of PLLA phases. Homogeneous phase distribution (arrangement) is obtained by extending the duration of mechanical milling.",
journal = "Materials Transactions. JIM / Japan Institute of Metals",
title = "The formation and characterization of nanocrystalline phases by mechanical milling of biphasic calcium phosphate/poly-L-lactide biocomposite",
volume = "47",
number = "12",
pages = "2980-2986",
doi = "10.2320/matertrans.47.2980"
}
Nikcevic, I., Maravić, D. S., Ignjatović, N. L., Mitrić, M., Makovec, D.,& Uskoković, D.. (2006). The formation and characterization of nanocrystalline phases by mechanical milling of biphasic calcium phosphate/poly-L-lactide biocomposite. in Materials Transactions. JIM / Japan Institute of Metals, 47(12), 2980-2986.
https://doi.org/10.2320/matertrans.47.2980
Nikcevic I, Maravić DS, Ignjatović NL, Mitrić M, Makovec D, Uskoković D. The formation and characterization of nanocrystalline phases by mechanical milling of biphasic calcium phosphate/poly-L-lactide biocomposite. in Materials Transactions. JIM / Japan Institute of Metals. 2006;47(12):2980-2986.
doi:10.2320/matertrans.47.2980 .
Nikcevic, I., Maravić, Dubravka S., Ignjatović, Nenad L., Mitrić, Miodrag, Makovec, Darko, Uskoković, Dragan, "The formation and characterization of nanocrystalline phases by mechanical milling of biphasic calcium phosphate/poly-L-lactide biocomposite" in Materials Transactions. JIM / Japan Institute of Metals, 47, no. 12 (2006):2980-2986,
https://doi.org/10.2320/matertrans.47.2980 . .
10
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