Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200125 (University of Novi Sad, Faculty of Science)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200125 (University of Novi Sad, Faculty of Science) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200125 (Univerzitet u Novom Sadu, Prirodno-matematički fakultet) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200125 (Универзитет у Новом Саду, Природно-математички факултет) (sr)
Authors

Publications

Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior

Antonijević-Nikolić, Mirjana; Szécsényi, Katalin Mészáros; Dražić, Branka; Rodić, Marko V.; Stanić, Vojislav; Tanasković, Slađana

(2021)

TY  - JOUR
AU  - Antonijević-Nikolić, Mirjana
AU  - Szécsényi, Katalin Mészáros
AU  - Dražić, Branka
AU  - Rodić, Marko V.
AU  - Stanić, Vojislav
AU  - Tanasković, Slađana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9160
AB  - In vitro cytotoxic evaluation, formation constants and thermal stability of four mixed-ligand Co(II) complexes with tpmc = N,N',N",N'"-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane and carboxylate/dicarboxylate co-ligands of formulas [Co2(benz)2tpmc](ClO4)2•3H2O (1), benz– = benzoate anion; [Co2(L)tpmc](ClO4)2•nH2O, L = pht2– (phthalate dianion), n=2 (2), L = ipht2– (isophthalate dianion), n=4 (3) and L = tpht2–(terephthalate dianion), n=4 (4) are reported. The stoichiometric composition of the compounds in the solution were determined spectrophotometrically using Job's methods. Formation constants, K and Gibbs free energy, ΔG values were calculated. The thermal behavior of the complexes was investigated by simultaneous TG/DSC and TG – MS measurements. The cytotoxic effect of the complexes, the free ligands, the DMSO solvent and cis-platin, as referent cytostatic drug, was evaluated on Human cervix adenocarcinoma (HeLa), human melanoma (Fem-x) and human colon carcinoma (LS174) cell lines. The IC50 values were between 12.7–42.3 μM. The first crystal structure determination of the Co(II) complex [Co2(µ-pht)tpmc](ClO4)2•H2O with boat conformation of tpmc ligand, was also done. The complex crystallizes in monoclinic crystal system, C2/c space group. The geometries around both Co(II) atoms are highly distorted octahedral. The Co(II) ions exhibit CoN4O2 coordination environments with the four nitrogen donor atoms of the tpmc ligand and two oxygen atoms belonging to the one carboxylate group of pht2− ligand. The carboxylate groups of pht2− are coordinated in an endo-bidentate mode. The tpmc ligand adopted a boat conformation in which the two coordinated Co(II) atoms are located on the same side of the ring, with Co•••Co distance amounting 5.4799(5) Å. © 2021
T2  - Journal of Molecular Structure
T1  - Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior
VL  - 1236
SP  - 130133
DO  - 10.1016/j.molstruc.2021.130133
ER  - 
@article{
author = "Antonijević-Nikolić, Mirjana and Szécsényi, Katalin Mészáros and Dražić, Branka and Rodić, Marko V. and Stanić, Vojislav and Tanasković, Slađana",
year = "2021",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9160",
abstract = "In vitro cytotoxic evaluation, formation constants and thermal stability of four mixed-ligand Co(II) complexes with tpmc = N,N',N",N'"-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane and carboxylate/dicarboxylate co-ligands of formulas [Co2(benz)2tpmc](ClO4)2•3H2O (1), benz– = benzoate anion; [Co2(L)tpmc](ClO4)2•nH2O, L = pht2– (phthalate dianion), n=2 (2), L = ipht2– (isophthalate dianion), n=4 (3) and L = tpht2–(terephthalate dianion), n=4 (4) are reported. The stoichiometric composition of the compounds in the solution were determined spectrophotometrically using Job's methods. Formation constants, K and Gibbs free energy, ΔG values were calculated. The thermal behavior of the complexes was investigated by simultaneous TG/DSC and TG – MS measurements. The cytotoxic effect of the complexes, the free ligands, the DMSO solvent and cis-platin, as referent cytostatic drug, was evaluated on Human cervix adenocarcinoma (HeLa), human melanoma (Fem-x) and human colon carcinoma (LS174) cell lines. The IC50 values were between 12.7–42.3 μM. The first crystal structure determination of the Co(II) complex [Co2(µ-pht)tpmc](ClO4)2•H2O with boat conformation of tpmc ligand, was also done. The complex crystallizes in monoclinic crystal system, C2/c space group. The geometries around both Co(II) atoms are highly distorted octahedral. The Co(II) ions exhibit CoN4O2 coordination environments with the four nitrogen donor atoms of the tpmc ligand and two oxygen atoms belonging to the one carboxylate group of pht2− ligand. The carboxylate groups of pht2− are coordinated in an endo-bidentate mode. The tpmc ligand adopted a boat conformation in which the two coordinated Co(II) atoms are located on the same side of the ring, with Co•••Co distance amounting 5.4799(5) Å. © 2021",
journal = "Journal of Molecular Structure",
title = "Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior",
volume = "1236",
pages = "130133",
doi = "10.1016/j.molstruc.2021.130133"
}
Antonijević-Nikolić, M., Szécsényi, K. M., Dražić, B., Rodić, M. V., Stanić, V.,& Tanasković, S. (2021). Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior.
Journal of Molecular Structure, 1236, 130133.
https://doi.org/10.1016/j.molstruc.2021.130133
Antonijević-Nikolić M, Szécsényi KM, Dražić B, Rodić MV, Stanić V, Tanasković S. Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior. Journal of Molecular Structure. 2021;1236:130133
Antonijević-Nikolić Mirjana, Szécsényi Katalin Mészáros, Dražić Branka, Rodić Marko V., Stanić Vojislav, Tanasković Slađana, "Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior" Journal of Molecular Structure, 1236 (2021):130133,
https://doi.org/10.1016/j.molstruc.2021.130133 .

The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity

Jović, Danica; Jaćević, Vesna; Kuča, Kamil; Borišev, Ivana; Mrđanović, Jasminka; Petrović, Danijela; Seke, Mariana; Đorđević, Aleksandar

(2020)

TY  - JOUR
AU  - Jović, Danica
AU  - Jaćević, Vesna
AU  - Kuča, Kamil
AU  - Borišev, Ivana
AU  - Mrđanović, Jasminka
AU  - Petrović, Danijela
AU  - Seke, Mariana
AU  - Đorđević, Aleksandar
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9120
AB  - Being a member of the nanofamily, carbon nanomaterials exhibit specific properties that mostly arise from their small size. They have proved to be very promising for application in the technical and biomedical field. A wide spectrum of use implies the inevitable presence of carbon nanomaterials in the environment, thus potentially endangering their whole nature. Although scientists worldwide have conducted research investigating the impact of these materials, it is evident that there are still significant gaps concerning the knowledge of their mechanisms, as well as the prolonged and chronic exposure and effects. This manuscript summarizes the most prominent representatives of carbon nanomaterial groups, giving a brief review of their general physico-chemical properties, the most common use, and toxicity profiles. Toxicity was presented through genotoxicity and the activation of the cell signaling pathways, both including in vitro and in vivo models, mechanisms, and the consequential outcomes. Moreover, the acute toxicity of fullerenol, as one of the most commonly investigated members, was briefly presented in the final part of this review. Thinking small can greatly help us improve our lives, but also obliges us to deeply and comprehensively investigate all the possible consequences that could arise from our pure-hearted scientific ambitions and work.
T2  - Nanomaterials
T1  - The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity
VL  - 10
IS  - 8
SP  - 1508
DO  - 10.3390/nano10081508
ER  - 
@article{
author = "Jović, Danica and Jaćević, Vesna and Kuča, Kamil and Borišev, Ivana and Mrđanović, Jasminka and Petrović, Danijela and Seke, Mariana and Đorđević, Aleksandar",
year = "2020",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/9120",
abstract = "Being a member of the nanofamily, carbon nanomaterials exhibit specific properties that mostly arise from their small size. They have proved to be very promising for application in the technical and biomedical field. A wide spectrum of use implies the inevitable presence of carbon nanomaterials in the environment, thus potentially endangering their whole nature. Although scientists worldwide have conducted research investigating the impact of these materials, it is evident that there are still significant gaps concerning the knowledge of their mechanisms, as well as the prolonged and chronic exposure and effects. This manuscript summarizes the most prominent representatives of carbon nanomaterial groups, giving a brief review of their general physico-chemical properties, the most common use, and toxicity profiles. Toxicity was presented through genotoxicity and the activation of the cell signaling pathways, both including in vitro and in vivo models, mechanisms, and the consequential outcomes. Moreover, the acute toxicity of fullerenol, as one of the most commonly investigated members, was briefly presented in the final part of this review. Thinking small can greatly help us improve our lives, but also obliges us to deeply and comprehensively investigate all the possible consequences that could arise from our pure-hearted scientific ambitions and work.",
journal = "Nanomaterials",
title = "The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity",
volume = "10",
number = "8",
pages = "1508",
doi = "10.3390/nano10081508"
}
Jović, D., Jaćević, V., Kuča, K., Borišev, I., Mrđanović, J., Petrović, D., Seke, M.,& Đorđević, A. (2020). The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity.
Nanomaterials, 10(8), 1508.
https://doi.org/10.3390/nano10081508
Jović D, Jaćević V, Kuča K, Borišev I, Mrđanović J, Petrović D, Seke M, Đorđević A. The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity. Nanomaterials. 2020;10(8):1508
Jović Danica, Jaćević Vesna, Kuča Kamil, Borišev Ivana, Mrđanović Jasminka, Petrović Danijela, Seke Mariana, Đorđević Aleksandar, "The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity" Nanomaterials, 10, no. 8 (2020):1508,
https://doi.org/10.3390/nano10081508 .
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Complexity of Shapiro steps

Mali, Petar; Šakota, Anđela; Tekić, Jasmina; Radošević, Slobodan; Pantić, Milan; Pavkov-Hrvojević, Milica

(2020)

TY  - JOUR
AU  - Mali, Petar
AU  - Šakota, Anđela
AU  - Tekić, Jasmina
AU  - Radošević, Slobodan
AU  - Pantić, Milan
AU  - Pavkov-Hrvojević, Milica
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8931
AB  - We demonstrate, using the example of the dc+ac driven overdamped Frenkel-Kontorova model, that an easily calculable measure of complexity can be used for the examination of Shapiro steps in the presence of thermal noise. In real systems, thermal noise causes melting or even disappearance of Shapiro steps, which makes their analysis in the standard way from the response function difficult. Unlike in the conventional approach, here, by calculating the Kolmogorov complexity of certain areas in the response function, we were able to detect Shapiro steps, measure their size with the desired precision, and examine their temperature dependence. The aim of this work is to provide scientists, particularly experimentalists, with an unconventional, but practical and easy tool for examination of Shapiro steps in real systems.
T2  - Physical Review E
T1  - Complexity of Shapiro steps
VL  - 101
IS  - 3
SP  - 032203
DO  - 10.1103/PhysRevE.101.032203
ER  - 
@article{
author = "Mali, Petar and Šakota, Anđela and Tekić, Jasmina and Radošević, Slobodan and Pantić, Milan and Pavkov-Hrvojević, Milica",
year = "2020",
url = "https://vinar.vin.bg.ac.rs/handle/123456789/8931",
abstract = "We demonstrate, using the example of the dc+ac driven overdamped Frenkel-Kontorova model, that an easily calculable measure of complexity can be used for the examination of Shapiro steps in the presence of thermal noise. In real systems, thermal noise causes melting or even disappearance of Shapiro steps, which makes their analysis in the standard way from the response function difficult. Unlike in the conventional approach, here, by calculating the Kolmogorov complexity of certain areas in the response function, we were able to detect Shapiro steps, measure their size with the desired precision, and examine their temperature dependence. The aim of this work is to provide scientists, particularly experimentalists, with an unconventional, but practical and easy tool for examination of Shapiro steps in real systems.",
journal = "Physical Review E",
title = "Complexity of Shapiro steps",
volume = "101",
number = "3",
pages = "032203",
doi = "10.1103/PhysRevE.101.032203"
}
Mali, P., Šakota, A., Tekić, J., Radošević, S., Pantić, M.,& Pavkov-Hrvojević, M. (2020). Complexity of Shapiro steps.
Physical Review E, 101(3), 032203.
https://doi.org/10.1103/PhysRevE.101.032203
Mali P, Šakota A, Tekić J, Radošević S, Pantić M, Pavkov-Hrvojević M. Complexity of Shapiro steps. Physical Review E. 2020;101(3):032203
Mali Petar, Šakota Anđela, Tekić Jasmina, Radošević Slobodan, Pantić Milan, Pavkov-Hrvojević Milica, "Complexity of Shapiro steps" Physical Review E, 101, no. 3 (2020):032203,
https://doi.org/10.1103/PhysRevE.101.032203 .
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