TY  - JOUR
AU  - Jokanović, Vukoman R.
AU  - Bundaleski, Nenad
AU  - Petrović, Božana
AU  - Ferarra, Manuela
AU  - Jokanović, Bojan
AU  - Živković, Slavoljub
AU  - Nasov, Ilija
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10029
AB  - Thin films on the base of titanium oxynitrides and copper doped titanium nitride were obtained by a combination of different PVD techniques on the surface of glass substrate and their physicochemical properties were analyzed in details. Phase composition of the samples was analyzed by XRD and FTIR methods, while microstructure of the samples was analyzed by SEM. XPS was used for depth profiling of the samples, which enabled determination of the oxidative state of titanium and corresponding phases through various film layers from the surface to the substrate. The depth of the various layers and their extinction coefficients and refractory indexes were estimated by spectroscopic ellipsometry.
T2  - Vacuum
T1  - Detailed phisyco-chemical characterization of the multilayered thin films based on titanium oxynitride and copper doped titanium nitride obtained by different PVD techniques
VL  - 195
SP  - 110708
DO  - 10.1016/j.vacuum.2021.110708
ER  - 

@article{
author = "Jokanović, Vukoman R. and Bundaleski, Nenad and Petrović, Božana and Ferarra, Manuela and Jokanović, Bojan and Živković, Slavoljub and Nasov, Ilija",
year = "2022",
abstract = "Thin films on the base of titanium oxynitrides and copper doped titanium nitride were obtained by a combination of different PVD techniques on the surface of glass substrate and their physicochemical properties were analyzed in details. Phase composition of the samples was analyzed by XRD and FTIR methods, while microstructure of the samples was analyzed by SEM. XPS was used for depth profiling of the samples, which enabled determination of the oxidative state of titanium and corresponding phases through various film layers from the surface to the substrate. The depth of the various layers and their extinction coefficients and refractory indexes were estimated by spectroscopic ellipsometry.",
journal = "Vacuum",
title = "Detailed phisyco-chemical characterization of the multilayered thin films based on titanium oxynitride and copper doped titanium nitride obtained by different PVD techniques",
volume = "195",
pages = "110708",
doi = "10.1016/j.vacuum.2021.110708"
}

Jokanović, V. R., Bundaleski, N., Petrović, B., Ferarra, M., Jokanović, B., Živković, S.,& Nasov, I.. (2022). Detailed phisyco-chemical characterization of the multilayered thin films based on titanium oxynitride and copper doped titanium nitride obtained by different PVD techniques. in Vacuum, 195, 110708.
https://doi.org/10.1016/j.vacuum.2021.110708

Jokanović VR, Bundaleski N, Petrović B, Ferarra M, Jokanović B, Živković S, Nasov I. Detailed phisyco-chemical characterization of the multilayered thin films based on titanium oxynitride and copper doped titanium nitride obtained by different PVD techniques. in Vacuum. 2022;195:110708.
doi:10.1016/j.vacuum.2021.110708 .

Jokanović, Vukoman R., Bundaleski, Nenad, Petrović, Božana, Ferarra, Manuela, Jokanović, Bojan, Živković, Slavoljub, Nasov, Ilija, "Detailed phisyco-chemical characterization of the multilayered thin films based on titanium oxynitride and copper doped titanium nitride obtained by different PVD techniques" in Vacuum, 195 (2022):110708,
https://doi.org/10.1016/j.vacuum.2021.110708 . .

TY  - JOUR
AU  - Milutinović-Smiljanić, Sanja
AU  - Antonijević, Đorđe
AU  - Mićić, Milutin
AU  - Biočanin, Vladimir
AU  - Sjerobabin, Nikola
AU  - Petrović, Božana
AU  - Danilović, Vesna
AU  - Jokanović, Vukoman R.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11221
AB  - Background/Aim. The materials used nowadays for bone replacement do not fully meet the requirements for complete regeneration, which is why new ones are being tested. Despite numerous attempts to improve bone tissue regeneration, no fulfilling material has been found yet. This study investigated the influence of poly-lactide-co-glycolide (PLGA) and polyethyleneimine (PEI) as coatings for hydroxyapatite (HAP) bone carriers on bone tissue regenerative potential in rabbits? calvarial defect. Methods. Calvarial defects measuring 6 mm in diameter were made in 19 skeletally mature rabbits. Defects were filled with one of the following materials: PLGA coated HAP (HAP + PLGA), PEI coated HAP (HAP + PEI), and bovine HAP ? Bio-Oss? (positive control). Unfilled defects represented negative control. Histological analysis was performed in order to determine the inflammatory response of the host tissue. The formation of the new bone was evaluated using histomorphometric analysis. All analyses have been conducted in samples obtained 3, 6, and 9 weeks after implantation. Results. Three weeks post-implantation, a trend toward increased healing in the HAP + PLGA group compared to other investigated materials was noticed, with no statistically significant difference between the study groups (p > 0.05). However, after 6 and 9 weeks, significant healing was observed in favor of the HAP coated with PLGA compared to other groups (p
AB  - Uvod/Cilj. Materijali koji se u današnje vreme koriste za nadoknadu koštanog tkiva ne dovode do kompletne regeneracije, zbog čega se ispituju novi. Uprkos mnogobrojnim pokušajima da se poboljša regeneracija koštanog tkiva, još uvek nije pronađen materijal koji ispunjava sve kriterijume. Cilj rada bio je da se utvrdi uticaj poli(laktid-ko-glikolida) (PLGA) i polietilenimina (PEI), kao premaza za oblaganje hidroksiapatita (HAP), na regenerativni potencijal koštanog tkiva u defektu kalvarije zeca. Metode. Kod 19 zečeva „zrelog” skeleta načinjeni su defekti kalvarije dijametra 6 mm. Defekti su potom ispunjeni jednim od sledećih materijala: HAP obložen PLGA (HAP + PLGA), HAP obložen PEI (HAP + PEI) i goveđi HAP – Bio-Oss® (pozitivna kontrola). Prazni defekti su predstavljali negativnu kontrolu. Inflamacijska reakcija tkiva domaćina je ispitana histološkom analizom. Formiranje nove kosti je procenjivano histomorfometrijskom analizom. Analizirani su uzorci dobijeni 3, 6 i 9 nedelja nakon implantacije. Rezultati. Tri nedelje nakon implantacije, uočena je tendencija boljeg zarastanja u HAP + PLGA grupi, bez statistički značajne razlike između ispitivanih grupa (p > 0.05). Međutim, 6 i 9 nedelja nakon implantacije, primećeno je značajno formiranje koštanog tkiva u korist HAP + PLGA grupe (p < 0,05). Oblaganje HAP sa PLGA dovelo je do boljeg koštanog zarastanja u poređenju sa HAP+PEI i Bio-Oss®. Zaključak. U pogledu stimulisanja osteogeneze u rekonstruktivnoj hirurgiji kostiju, PLGA je pokazao veći potencijal prekrivanja defekta od PEI.
T2  - Vojnosanitetski pregled
T1  - The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis
T1  - Uticaj različitih materijala koji oblažu hidroksiapatit koštanog nosača na uspeh regeneracije koštanih defekta kalvarije zeca: histomorfometrijska i histološka analiza
VL  - 79
IS  - 10
SP  - 1025
EP  - 1034
DO  - 10.2298/VSP210513072M
ER  - 

@article{
author = "Milutinović-Smiljanić, Sanja and Antonijević, Đorđe and Mićić, Milutin and Biočanin, Vladimir and Sjerobabin, Nikola and Petrović, Božana and Danilović, Vesna and Jokanović, Vukoman R.",
year = "2022",
abstract = "Background/Aim. The materials used nowadays for bone replacement do not fully meet the requirements for complete regeneration, which is why new ones are being tested. Despite numerous attempts to improve bone tissue regeneration, no fulfilling material has been found yet. This study investigated the influence of poly-lactide-co-glycolide (PLGA) and polyethyleneimine (PEI) as coatings for hydroxyapatite (HAP) bone carriers on bone tissue regenerative potential in rabbits? calvarial defect. Methods. Calvarial defects measuring 6 mm in diameter were made in 19 skeletally mature rabbits. Defects were filled with one of the following materials: PLGA coated HAP (HAP + PLGA), PEI coated HAP (HAP + PEI), and bovine HAP ? Bio-Oss? (positive control). Unfilled defects represented negative control. Histological analysis was performed in order to determine the inflammatory response of the host tissue. The formation of the new bone was evaluated using histomorphometric analysis. All analyses have been conducted in samples obtained 3, 6, and 9 weeks after implantation. Results. Three weeks post-implantation, a trend toward increased healing in the HAP + PLGA group compared to other investigated materials was noticed, with no statistically significant difference between the study groups (p > 0.05). However, after 6 and 9 weeks, significant healing was observed in favor of the HAP coated with PLGA compared to other groups (p, Uvod/Cilj. Materijali koji se u današnje vreme koriste za nadoknadu koštanog tkiva ne dovode do kompletne regeneracije, zbog čega se ispituju novi. Uprkos mnogobrojnim pokušajima da se poboljša regeneracija koštanog tkiva, još uvek nije pronađen materijal koji ispunjava sve kriterijume. Cilj rada bio je da se utvrdi uticaj poli(laktid-ko-glikolida) (PLGA) i polietilenimina (PEI), kao premaza za oblaganje hidroksiapatita (HAP), na regenerativni potencijal koštanog tkiva u defektu kalvarije zeca. Metode. Kod 19 zečeva „zrelog” skeleta načinjeni su defekti kalvarije dijametra 6 mm. Defekti su potom ispunjeni jednim od sledećih materijala: HAP obložen PLGA (HAP + PLGA), HAP obložen PEI (HAP + PEI) i goveđi HAP – Bio-Oss® (pozitivna kontrola). Prazni defekti su predstavljali negativnu kontrolu. Inflamacijska reakcija tkiva domaćina je ispitana histološkom analizom. Formiranje nove kosti je procenjivano histomorfometrijskom analizom. Analizirani su uzorci dobijeni 3, 6 i 9 nedelja nakon implantacije. Rezultati. Tri nedelje nakon implantacije, uočena je tendencija boljeg zarastanja u HAP + PLGA grupi, bez statistički značajne razlike između ispitivanih grupa (p > 0.05). Međutim, 6 i 9 nedelja nakon implantacije, primećeno je značajno formiranje koštanog tkiva u korist HAP + PLGA grupe (p < 0,05). Oblaganje HAP sa PLGA dovelo je do boljeg koštanog zarastanja u poređenju sa HAP+PEI i Bio-Oss®. Zaključak. U pogledu stimulisanja osteogeneze u rekonstruktivnoj hirurgiji kostiju, PLGA je pokazao veći potencijal prekrivanja defekta od PEI.",
journal = "Vojnosanitetski pregled",
title = "The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis, Uticaj različitih materijala koji oblažu hidroksiapatit koštanog nosača na uspeh regeneracije koštanih defekta kalvarije zeca: histomorfometrijska i histološka analiza",
volume = "79",
number = "10",
pages = "1025-1034",
doi = "10.2298/VSP210513072M"
}

Milutinović-Smiljanić, S., Antonijević, Đ., Mićić, M., Biočanin, V., Sjerobabin, N., Petrović, B., Danilović, V.,& Jokanović, V. R.. (2022). The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis. in Vojnosanitetski pregled, 79(10), 1025-1034.
https://doi.org/10.2298/VSP210513072M

Milutinović-Smiljanić S, Antonijević Đ, Mićić M, Biočanin V, Sjerobabin N, Petrović B, Danilović V, Jokanović VR. The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis. in Vojnosanitetski pregled. 2022;79(10):1025-1034.
doi:10.2298/VSP210513072M .

Milutinović-Smiljanić, Sanja, Antonijević, Đorđe, Mićić, Milutin, Biočanin, Vladimir, Sjerobabin, Nikola, Petrović, Božana, Danilović, Vesna, Jokanović, Vukoman R., "The influence of various coatings of hydroxyapatite bone carrier on the success of bone regeneration in rabbit calvarial defects: Histomorphometric and histological analysis" in Vojnosanitetski pregled, 79, no. 10 (2022):1025-1034,
https://doi.org/10.2298/VSP210513072M . .

TY  - JOUR
AU  - Jokanović, Vukoman R.
AU  - Bundaleski, Nenad
AU  - Čolović, Božana M.
AU  - Ferarra, Manuela
AU  - Jokanović, Bojan
AU  - Nasov, Ilija
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9891
AB  - Physicochemical properties of thin films on the base of titanium oxides, obtained by a cathodic arc evaporation on the surface of glass substrate are analysed in details. The analysis of these films was made by using XRD, FTIR, SEM, XPS analysis and ellipsometry. On the basis of these analyses, particularly analysis obtained by XPS, the oxidative state Ti and corresponding phases are determined through various film layers from the surface to the substrate. The depth of the various levels and their extinction coefficients and refractory indexes are estimated by ellipsometry.
T2  - Zaštita materijala
T1  - Detailed characterization of the Ti-O based thin films obtained by cathodic arc evaporation
VL  - 62
IS  - 1
SP  - 41
EP  - 50
DO  - 10.5937/zasmat2101041J
ER  - 

@article{
author = "Jokanović, Vukoman R. and Bundaleski, Nenad and Čolović, Božana M. and Ferarra, Manuela and Jokanović, Bojan and Nasov, Ilija",
year = "2021",
abstract = "Physicochemical properties of thin films on the base of titanium oxides, obtained by a cathodic arc evaporation on the surface of glass substrate are analysed in details. The analysis of these films was made by using XRD, FTIR, SEM, XPS analysis and ellipsometry. On the basis of these analyses, particularly analysis obtained by XPS, the oxidative state Ti and corresponding phases are determined through various film layers from the surface to the substrate. The depth of the various levels and their extinction coefficients and refractory indexes are estimated by ellipsometry.",
journal = "Zaštita materijala",
title = "Detailed characterization of the Ti-O based thin films obtained by cathodic arc evaporation",
volume = "62",
number = "1",
pages = "41-50",
doi = "10.5937/zasmat2101041J"
}

Jokanović, V. R., Bundaleski, N., Čolović, B. M., Ferarra, M., Jokanović, B.,& Nasov, I.. (2021). Detailed characterization of the Ti-O based thin films obtained by cathodic arc evaporation. in Zaštita materijala, 62(1), 41-50.
https://doi.org/10.5937/zasmat2101041J

Jokanović VR, Bundaleski N, Čolović BM, Ferarra M, Jokanović B, Nasov I. Detailed characterization of the Ti-O based thin films obtained by cathodic arc evaporation. in Zaštita materijala. 2021;62(1):41-50.
doi:10.5937/zasmat2101041J .

Jokanović, Vukoman R., Bundaleski, Nenad, Čolović, Božana M., Ferarra, Manuela, Jokanović, Bojan, Nasov, Ilija, "Detailed characterization of the Ti-O based thin films obtained by cathodic arc evaporation" in Zaštita materijala, 62, no. 1 (2021):41-50,
https://doi.org/10.5937/zasmat2101041J . .

TY  - JOUR
AU  - Paraš, Smiljana
AU  - Trišić, Dijana
AU  - Mitrović-Ajtić, Olivera
AU  - Antonijević, Đorđe
AU  - Čolović, Božana M.
AU  - Drobne, Damjana
AU  - Jokanović, Vukoman R.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9821
AB  - The effects of a new material based on hydroxyapatite and calcium silicates, named ALBO-MPCA, were investigated on the liver, kidney and spleen. The material was administrated orally for 120 days in an in vivo model in Wistar rats, and untreated animals served as a control. Hematological and biochemical blood parameters were analyzed. Qualitative histological analysis of tissues, change in mitotic activity of cells, and histological characteristics was conducted, as well as quantitative stereological analysis of parenchymal cells, blood sinusoids, and connective tissues. Additionally, the protein expressions of Ki67 and CD68 markers were evaluated. Histological analysis revealed no pathological changes after the tested period. It showed the preservation of the architecture of blood sinusoids and epithelial cells and the presence of mitosis. Additionally, the significantly increased number of the Ki67 in the presence of ALBO-MPCA confirmed the proliferative effect of the material noticed by stereological analysis, while immunoreactive CD68 positive cells did not differ between groups. The study showed non-toxicity of the tested material based on the effects on the hematological, biochemical, and observed histological parameters; in addition, it showed evidence of its biocompatibility. These results could be the basis for further steps toward the application of tested materials in endodontics.
T2  - International Journal of Molecular Science
T1  - Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects
VL  - 22
IS  - 11
SP  - 5468
DO  - 10.3390/ijms22115468
ER  - 

@article{
author = "Paraš, Smiljana and Trišić, Dijana and Mitrović-Ajtić, Olivera and Antonijević, Đorđe and Čolović, Božana M. and Drobne, Damjana and Jokanović, Vukoman R.",
year = "2021",
abstract = "The effects of a new material based on hydroxyapatite and calcium silicates, named ALBO-MPCA, were investigated on the liver, kidney and spleen. The material was administrated orally for 120 days in an in vivo model in Wistar rats, and untreated animals served as a control. Hematological and biochemical blood parameters were analyzed. Qualitative histological analysis of tissues, change in mitotic activity of cells, and histological characteristics was conducted, as well as quantitative stereological analysis of parenchymal cells, blood sinusoids, and connective tissues. Additionally, the protein expressions of Ki67 and CD68 markers were evaluated. Histological analysis revealed no pathological changes after the tested period. It showed the preservation of the architecture of blood sinusoids and epithelial cells and the presence of mitosis. Additionally, the significantly increased number of the Ki67 in the presence of ALBO-MPCA confirmed the proliferative effect of the material noticed by stereological analysis, while immunoreactive CD68 positive cells did not differ between groups. The study showed non-toxicity of the tested material based on the effects on the hematological, biochemical, and observed histological parameters; in addition, it showed evidence of its biocompatibility. These results could be the basis for further steps toward the application of tested materials in endodontics.",
journal = "International Journal of Molecular Science",
title = "Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects",
volume = "22",
number = "11",
pages = "5468",
doi = "10.3390/ijms22115468"
}

Paraš, S., Trišić, D., Mitrović-Ajtić, O., Antonijević, Đ., Čolović, B. M., Drobne, D.,& Jokanović, V. R.. (2021). Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects. in International Journal of Molecular Science, 22(11), 5468.
https://doi.org/10.3390/ijms22115468

Paraš S, Trišić D, Mitrović-Ajtić O, Antonijević Đ, Čolović BM, Drobne D, Jokanović VR. Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects. in International Journal of Molecular Science. 2021;22(11):5468.
doi:10.3390/ijms22115468 .

Paraš, Smiljana, Trišić, Dijana, Mitrović-Ajtić, Olivera, Antonijević, Đorđe, Čolović, Božana M., Drobne, Damjana, Jokanović, Vukoman R., "Biocompatibility study of a new dental cement based on hydroxyapatite and calcium silicates: Focus on liver, kidney, and spleen tissue effects" in International Journal of Molecular Science, 22, no. 11 (2021):5468,
https://doi.org/10.3390/ijms22115468 . .

TY  - JOUR
AU  - Magić, Marko
AU  - Čolović, Božana M.
AU  - Vasilijić, Saša
AU  - Tadić, Nenad
AU  - Stojadinović, Stevan
AU  - Jokanović, Vukoman R.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10041
AB  - The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
T2  - Journal of Applied Biomaterials & Functional Materials
T1  - Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity
VL  - 19
DO  - 10.1177/2280800018822252
ER  - 

@article{
author = "Magić, Marko and Čolović, Božana M. and Vasilijić, Saša and Tadić, Nenad and Stojadinović, Stevan and Jokanović, Vukoman R.",
year = "2021",
abstract = "The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.",
journal = "Journal of Applied Biomaterials & Functional Materials",
title = "Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity",
volume = "19",
doi = "10.1177/2280800018822252"
}

Magić, M., Čolović, B. M., Vasilijić, S., Tadić, N., Stojadinović, S.,& Jokanović, V. R.. (2021). Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity. in Journal of Applied Biomaterials & Functional Materials, 19.
https://doi.org/10.1177/2280800018822252

Magić M, Čolović BM, Vasilijić S, Tadić N, Stojadinović S, Jokanović VR. Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity. in Journal of Applied Biomaterials & Functional Materials. 2021;19.
doi:10.1177/2280800018822252 .

Magić, Marko, Čolović, Božana M., Vasilijić, Saša, Tadić, Nenad, Stojadinović, Stevan, Jokanović, Vukoman R., "Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity" in Journal of Applied Biomaterials & Functional Materials, 19 (2021),
https://doi.org/10.1177/2280800018822252 . .

TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Rogić Miladinović, Zorana
AU  - Krstić, Maja
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11469
AB  - Oligo (ethylene glycol) oligo (propylene glycol) methacrylates (OEGOPGMA) with diferent numbers of ethylene glycol (EG) and propylene glycol (PG) units in backbone were used for the preparation of new thermoresponsive POEGOPGMA hydrogels; EG6PG3MA and EG3PG6MA monomers were used; and three diferent POEGOPGMA hydrogels (PEG6PG3MA, PEG3PG6MA and P(EG6PG3/EG3PG6) MA copolymer with equal mol% of previous two) were fabricated from mono‑ mer–solvent (OEGOPGMA–water/ethanol) mixture by gamma radiation. Charac‑ terisation of the hydrogels was conducted by swelling, UV–Vis, scanning electron microscope, diferential scanning calorimetry and in  vitro biocompatibility (cyto‑ compatibility and haemolytic activity) investigations. The modelling of drug release and difusion characteristics was tested using cephalexin drug. For the frst time, it was shown how to efectively tune the volume phase transition temperature (VPTT) values of the hydrogels by changing the ratio of more hydrophilic (EG) and more hydrophobic (PG) units in (EGPG) “block” pendant chains. The obtained hydrogels revealed the great potential for diferent biomedical applications not only due to the possibility to tune VPTT in the desired way but also due to the good biocompatibil‑ ity and controlled drug delivery within the target temperature range.
T2  - Polymer Bulletin
T1  - Swelling properties and drug release of new biocompatible POEGOPGMA hydrogels with VPTT near to the human body temperature
VL  - 78
SP  - 2405
EP  - 2425
DO  - 10.1007/s00289-020-03217-0
ER  - 

@article{
author = "Suljovrujić, Edin H. and Rogić Miladinović, Zorana and Krstić, Maja",
year = "2021",
abstract = "Oligo (ethylene glycol) oligo (propylene glycol) methacrylates (OEGOPGMA) with diferent numbers of ethylene glycol (EG) and propylene glycol (PG) units in backbone were used for the preparation of new thermoresponsive POEGOPGMA hydrogels; EG6PG3MA and EG3PG6MA monomers were used; and three diferent POEGOPGMA hydrogels (PEG6PG3MA, PEG3PG6MA and P(EG6PG3/EG3PG6) MA copolymer with equal mol% of previous two) were fabricated from mono‑ mer–solvent (OEGOPGMA–water/ethanol) mixture by gamma radiation. Charac‑ terisation of the hydrogels was conducted by swelling, UV–Vis, scanning electron microscope, diferential scanning calorimetry and in  vitro biocompatibility (cyto‑ compatibility and haemolytic activity) investigations. The modelling of drug release and difusion characteristics was tested using cephalexin drug. For the frst time, it was shown how to efectively tune the volume phase transition temperature (VPTT) values of the hydrogels by changing the ratio of more hydrophilic (EG) and more hydrophobic (PG) units in (EGPG) “block” pendant chains. The obtained hydrogels revealed the great potential for diferent biomedical applications not only due to the possibility to tune VPTT in the desired way but also due to the good biocompatibil‑ ity and controlled drug delivery within the target temperature range.",
journal = "Polymer Bulletin",
title = "Swelling properties and drug release of new biocompatible POEGOPGMA hydrogels with VPTT near to the human body temperature",
volume = "78",
pages = "2405-2425",
doi = "10.1007/s00289-020-03217-0"
}

Suljovrujić, E. H., Rogić Miladinović, Z.,& Krstić, M.. (2021). Swelling properties and drug release of new biocompatible POEGOPGMA hydrogels with VPTT near to the human body temperature. in Polymer Bulletin, 78, 2405-2425.
https://doi.org/10.1007/s00289-020-03217-0

Suljovrujić EH, Rogić Miladinović Z, Krstić M. Swelling properties and drug release of new biocompatible POEGOPGMA hydrogels with VPTT near to the human body temperature. in Polymer Bulletin. 2021;78:2405-2425.
doi:10.1007/s00289-020-03217-0 .

Suljovrujić, Edin H., Rogić Miladinović, Zorana, Krstić, Maja, "Swelling properties and drug release of new biocompatible POEGOPGMA hydrogels with VPTT near to the human body temperature" in Polymer Bulletin, 78 (2021):2405-2425,
https://doi.org/10.1007/s00289-020-03217-0 . .

TY  - JOUR
AU  - Petrović, Violeta
AU  - Opačić-Galić, Vanja
AU  - Jokanović, Vukoman R.
AU  - Sopta, Jelena
AU  - Prokić, Bogomir Bolka
AU  - Živković, Slavoljub
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9159
AB  - The aim of the study was to evaluate inflammatory tissue reactions and the formation of calcified tissue after implantation of experimental nanostructured calcium silicate cement (CS) and hydroxyapatite with calcium silicate cement (HA-CS) into root canals of rabbits' teeth. The study was conducted on four rabbits of the genus Oryctolagus cuniculus. After instrumentation and irrigation, the root canals of the central incisors were dried and filled with CS, HA-CS and control material (MTA Angelus). The animals were sacrificed after 28 days. After histological preparation and hematoxylin-eosin staining, tissue samples were evaluated for the intensity and extension of inflammatory tissue reaction; continuity, morphology and thickness of the newly formed calcified tissue; and presence of giant cells, materials particles and microorganisms. Kruskal Wallis and Dunn's post hoc test were used for data analysis (α=0.05). There were no significant differences in the intensity of inflammatory reactions between CS, HA-CS and MTA control. HA-CS showed significantly better results than MTA and CS with respect to continuity of the newly formed calcified tissue (P=0.003 and P=0.010, respectively). Significant differences in thickness of the calcified tissue existed between CS and MTA (P=0.004) and between HA-CS and MTA (P=0.012). Application of CS and HA-CS resulted in minimal inflammatory tissue response, similar to the MTA control. CS and HA-CS were more efficient than MTA in supporting hard tissue formation. The best organized newly formed calcified tissue was seen after HA-CS application.
AB  - Cilj rada je bio da se ispitaju Kanali korena centralnih sekutića su posle instrumentacije, ispiranja i sušenja napunjeni materijalima CS, HA-CS i kontrolnim materijalom, mineral trioksid agregatom (MTA). Životinje su žrtvovane posle 28 dana. Posle histološke pripreme, uzorci tkiva su analizirani u pogledu inteziteta i raširenosti zapaljenske reakcije; kontinuiteta, morfologije i debljine novoformiranog kalcifi kovanog tkiva; prisustva džinovskih ćelija, čestica materijala i mikroorganizama. Dobijeni rezultati su statistički obrađeni (α = 0,05) Nisu uočene statistički značajne razlike u intezitetu zapaljenske reakcije između CS, HA-CS i MTA. U pogledu kontinuiteta novostvorenog kalcifi kovanog tkiva HA-CS je pokazao bolje rezultate u odnosu na MTA i CS (p=0,003 i p=0,010). Značajne razlike utvrđene su u pogledu debljine kalcifi kovanog tkiva između CS i MTA (p=0,004), kao i HA-CS i MTA (p=0,012). Aplikacija materijala CS i HA-CS je rezultirala minimalnom zapaljenskom reakcijom tkiva, slično kontrolnom materijalu (MTA). CS i HA-CS su bili efi kasniji u pogledu stimulacije formiranja kalcifi kovanog tkiva u odnosu na MTA. Najbolje organizovano novoformirano tkivo uočeno je posle aplikacije materijala HA-CS. zapaljenske reakcije u periradikularnom tkivu i formiranje kalcifi kovanog tkiva posle implantacije eksperimentalnih, nanostrukturnih cemenata na bazi kalcijum silikata (CS) i mešavine hidroksiapatita i kalcijum silikata (HA-CS) u kanale korena zuba kunića.
T2  - Acta Veterinaria, Beograd
T1  - Histological Evaluation of Periradicular Tissue Inflammatory Reactions and Calcified Tissue Formations after Implantation of Experimental Calcium Silicate and Hydroxyapatite Based Nanostructural Cements into Root Canals of Rabbits Teeth
T1  - Histološka analiza zapaljenskih reakcija u periradikularnom tkivu i formiranja kalcifikovanog tkiva posle implantacije eksperimentalnih nanostrukturnih cemenata na bazi kalcijum silikata i hidroksiapatita u kanale korena zuba kunića
VL  - 71
IS  - 1
SP  - 85
EP  - 97
DO  - 10.2478/acve-2021-0006
ER  - 

@article{
author = "Petrović, Violeta and Opačić-Galić, Vanja and Jokanović, Vukoman R. and Sopta, Jelena and Prokić, Bogomir Bolka and Živković, Slavoljub",
year = "2021",
abstract = "The aim of the study was to evaluate inflammatory tissue reactions and the formation of calcified tissue after implantation of experimental nanostructured calcium silicate cement (CS) and hydroxyapatite with calcium silicate cement (HA-CS) into root canals of rabbits' teeth. The study was conducted on four rabbits of the genus Oryctolagus cuniculus. After instrumentation and irrigation, the root canals of the central incisors were dried and filled with CS, HA-CS and control material (MTA Angelus). The animals were sacrificed after 28 days. After histological preparation and hematoxylin-eosin staining, tissue samples were evaluated for the intensity and extension of inflammatory tissue reaction; continuity, morphology and thickness of the newly formed calcified tissue; and presence of giant cells, materials particles and microorganisms. Kruskal Wallis and Dunn's post hoc test were used for data analysis (α=0.05). There were no significant differences in the intensity of inflammatory reactions between CS, HA-CS and MTA control. HA-CS showed significantly better results than MTA and CS with respect to continuity of the newly formed calcified tissue (P=0.003 and P=0.010, respectively). Significant differences in thickness of the calcified tissue existed between CS and MTA (P=0.004) and between HA-CS and MTA (P=0.012). Application of CS and HA-CS resulted in minimal inflammatory tissue response, similar to the MTA control. CS and HA-CS were more efficient than MTA in supporting hard tissue formation. The best organized newly formed calcified tissue was seen after HA-CS application., Cilj rada je bio da se ispitaju Kanali korena centralnih sekutića su posle instrumentacije, ispiranja i sušenja napunjeni materijalima CS, HA-CS i kontrolnim materijalom, mineral trioksid agregatom (MTA). Životinje su žrtvovane posle 28 dana. Posle histološke pripreme, uzorci tkiva su analizirani u pogledu inteziteta i raširenosti zapaljenske reakcije; kontinuiteta, morfologije i debljine novoformiranog kalcifi kovanog tkiva; prisustva džinovskih ćelija, čestica materijala i mikroorganizama. Dobijeni rezultati su statistički obrađeni (α = 0,05) Nisu uočene statistički značajne razlike u intezitetu zapaljenske reakcije između CS, HA-CS i MTA. U pogledu kontinuiteta novostvorenog kalcifi kovanog tkiva HA-CS je pokazao bolje rezultate u odnosu na MTA i CS (p=0,003 i p=0,010). Značajne razlike utvrđene su u pogledu debljine kalcifi kovanog tkiva između CS i MTA (p=0,004), kao i HA-CS i MTA (p=0,012). Aplikacija materijala CS i HA-CS je rezultirala minimalnom zapaljenskom reakcijom tkiva, slično kontrolnom materijalu (MTA). CS i HA-CS su bili efi kasniji u pogledu stimulacije formiranja kalcifi kovanog tkiva u odnosu na MTA. Najbolje organizovano novoformirano tkivo uočeno je posle aplikacije materijala HA-CS. zapaljenske reakcije u periradikularnom tkivu i formiranje kalcifi kovanog tkiva posle implantacije eksperimentalnih, nanostrukturnih cemenata na bazi kalcijum silikata (CS) i mešavine hidroksiapatita i kalcijum silikata (HA-CS) u kanale korena zuba kunića.",
journal = "Acta Veterinaria, Beograd",
title = "Histological Evaluation of Periradicular Tissue Inflammatory Reactions and Calcified Tissue Formations after Implantation of Experimental Calcium Silicate and Hydroxyapatite Based Nanostructural Cements into Root Canals of Rabbits Teeth, Histološka analiza zapaljenskih reakcija u periradikularnom tkivu i formiranja kalcifikovanog tkiva posle implantacije eksperimentalnih nanostrukturnih cemenata na bazi kalcijum silikata i hidroksiapatita u kanale korena zuba kunića",
volume = "71",
number = "1",
pages = "85-97",
doi = "10.2478/acve-2021-0006"
}

Petrović, V., Opačić-Galić, V., Jokanović, V. R., Sopta, J., Prokić, B. B.,& Živković, S.. (2021). Histological Evaluation of Periradicular Tissue Inflammatory Reactions and Calcified Tissue Formations after Implantation of Experimental Calcium Silicate and Hydroxyapatite Based Nanostructural Cements into Root Canals of Rabbits Teeth. in Acta Veterinaria, Beograd, 71(1), 85-97.
https://doi.org/10.2478/acve-2021-0006

Petrović V, Opačić-Galić V, Jokanović VR, Sopta J, Prokić BB, Živković S. Histological Evaluation of Periradicular Tissue Inflammatory Reactions and Calcified Tissue Formations after Implantation of Experimental Calcium Silicate and Hydroxyapatite Based Nanostructural Cements into Root Canals of Rabbits Teeth. in Acta Veterinaria, Beograd. 2021;71(1):85-97.
doi:10.2478/acve-2021-0006 .

Petrović, Violeta, Opačić-Galić, Vanja, Jokanović, Vukoman R., Sopta, Jelena, Prokić, Bogomir Bolka, Živković, Slavoljub, "Histological Evaluation of Periradicular Tissue Inflammatory Reactions and Calcified Tissue Formations after Implantation of Experimental Calcium Silicate and Hydroxyapatite Based Nanostructural Cements into Root Canals of Rabbits Teeth" in Acta Veterinaria, Beograd, 71, no. 1 (2021):85-97,
https://doi.org/10.2478/acve-2021-0006 . .

TY  - JOUR
AU  - Micić, Milutin
AU  - Antonijević, Đorđe
AU  - Milutinović-Smiljanić, Sanja
AU  - Trišić, Dijana
AU  - Čolović, Božana M.
AU  - Kosanović, Dejana
AU  - Prokić, Bogomir Bolka
AU  - Vasić, Jugoslav
AU  - Živković, Slavoljub
AU  - Milašin, Jelena
AU  - Danilović, Vesna
AU  - Đurić, Marija P.
AU  - Jokanović, Vukoman R.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8993
AB  - The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 μm. Radiography and micro-CT analysis depicted new bone apposition through the whole length of the reconstructed ulna with a small area of non-resorbed construct in the central area of defect. Histological analysis revealed new bone formation with both endochondral and endesmal type of ossification. Immunohistochemistry analysis depicted the presence of bone formation indicators-bone morphogenetic protein (BMP), osteocalcin (OCN) and osteopontin (OPN) within newly formed bone. Manufactured personalized construct acts as a "smart" responsive biomaterial capable of modulating the functionality and potential for the personalized bone reconstruction on a clinically relevant length scale.
T2  - Biomedizinische Technik
T1  - Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction
VL  - 65
IS  - 4
SP  - 491
EP  - 505
DO  - 10.1515/bmt-2019-0218
ER  - 

@article{
author = "Micić, Milutin and Antonijević, Đorđe and Milutinović-Smiljanić, Sanja and Trišić, Dijana and Čolović, Božana M. and Kosanović, Dejana and Prokić, Bogomir Bolka and Vasić, Jugoslav and Živković, Slavoljub and Milašin, Jelena and Danilović, Vesna and Đurić, Marija P. and Jokanović, Vukoman R.",
year = "2020",
abstract = "The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 μm. Radiography and micro-CT analysis depicted new bone apposition through the whole length of the reconstructed ulna with a small area of non-resorbed construct in the central area of defect. Histological analysis revealed new bone formation with both endochondral and endesmal type of ossification. Immunohistochemistry analysis depicted the presence of bone formation indicators-bone morphogenetic protein (BMP), osteocalcin (OCN) and osteopontin (OPN) within newly formed bone. Manufactured personalized construct acts as a "smart" responsive biomaterial capable of modulating the functionality and potential for the personalized bone reconstruction on a clinically relevant length scale.",
journal = "Biomedizinische Technik",
title = "Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction",
volume = "65",
number = "4",
pages = "491-505",
doi = "10.1515/bmt-2019-0218"
}

Micić, M., Antonijević, Đ., Milutinović-Smiljanić, S., Trišić, D., Čolović, B. M., Kosanović, D., Prokić, B. B., Vasić, J., Živković, S., Milašin, J., Danilović, V., Đurić, M. P.,& Jokanović, V. R.. (2020). Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. in Biomedizinische Technik, 65(4), 491-505.
https://doi.org/10.1515/bmt-2019-0218

Micić M, Antonijević Đ, Milutinović-Smiljanić S, Trišić D, Čolović BM, Kosanović D, Prokić BB, Vasić J, Živković S, Milašin J, Danilović V, Đurić MP, Jokanović VR. Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. in Biomedizinische Technik. 2020;65(4):491-505.
doi:10.1515/bmt-2019-0218 .

Micić, Milutin, Antonijević, Đorđe, Milutinović-Smiljanić, Sanja, Trišić, Dijana, Čolović, Božana M., Kosanović, Dejana, Prokić, Bogomir Bolka, Vasić, Jugoslav, Živković, Slavoljub, Milašin, Jelena, Danilović, Vesna, Đurić, Marija P., Jokanović, Vukoman R., "Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: Physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction" in Biomedizinische Technik, 65, no. 4 (2020):491-505,
https://doi.org/10.1515/bmt-2019-0218 . .

TY  - JOUR
AU  - Markushev, Dragana K.
AU  - Markushev, Dragan D.
AU  - Aleksić, Sanja M.
AU  - Pantić, Dragan S.
AU  - Galović, Slobodanka
AU  - Todorović, Dragan M.
AU  - Ordonez-Miranda, Jose
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9663
AB  - Based on the experimental and theoretical signals of an open photoacoustic cell operating with modulation frequencies from 20 Hz to
20 kHz, a significant contribution of photogenerated excess carriers on the thermal and thermoelastic responses of an n-type silicon plate is
observed for the very first time. This is achieved by comparing the measured amplitude and phase of the photoacoustic signal with their
corresponding theoretical thermoelastic counterparts, for high enough modulation frequencies mainly. It is shown that the amplitude of the
thermoelastic component of plasma-thin samples varies about two orders of magnitude with respect to the corresponding one of
plasma-thick samples. Furthermore, we find a maximal temperature difference ΔT =− 35 nK between the illuminated and non-illuminated
sample surfaces, which shows that thin silicon plates with excess carriers could be used as heat sinks.
T2  - Journal of Applied Physics
T1  - Experimental photoacoustic observation of the photogenerated excess carrier influence on the thermoelastic response of n-type silicon
VL  - 128
IS  - 9
SP  - 095103
DO  - 10.1063/5.0015657
ER  - 

@article{
author = "Markushev, Dragana K. and Markushev, Dragan D. and Aleksić, Sanja M. and Pantić, Dragan S. and Galović, Slobodanka and Todorović, Dragan M. and Ordonez-Miranda, Jose",
year = "2020",
abstract = "Based on the experimental and theoretical signals of an open photoacoustic cell operating with modulation frequencies from 20 Hz to
20 kHz, a significant contribution of photogenerated excess carriers on the thermal and thermoelastic responses of an n-type silicon plate is
observed for the very first time. This is achieved by comparing the measured amplitude and phase of the photoacoustic signal with their
corresponding theoretical thermoelastic counterparts, for high enough modulation frequencies mainly. It is shown that the amplitude of the
thermoelastic component of plasma-thin samples varies about two orders of magnitude with respect to the corresponding one of
plasma-thick samples. Furthermore, we find a maximal temperature difference ΔT =− 35 nK between the illuminated and non-illuminated
sample surfaces, which shows that thin silicon plates with excess carriers could be used as heat sinks.",
journal = "Journal of Applied Physics",
title = "Experimental photoacoustic observation of the photogenerated excess carrier influence on the thermoelastic response of n-type silicon",
volume = "128",
number = "9",
pages = "095103",
doi = "10.1063/5.0015657"
}

Markushev, D. K., Markushev, D. D., Aleksić, S. M., Pantić, D. S., Galović, S., Todorović, D. M.,& Ordonez-Miranda, J.. (2020). Experimental photoacoustic observation of the photogenerated excess carrier influence on the thermoelastic response of n-type silicon. in Journal of Applied Physics, 128(9), 095103.
https://doi.org/10.1063/5.0015657

Markushev DK, Markushev DD, Aleksić SM, Pantić DS, Galović S, Todorović DM, Ordonez-Miranda J. Experimental photoacoustic observation of the photogenerated excess carrier influence on the thermoelastic response of n-type silicon. in Journal of Applied Physics. 2020;128(9):095103.
doi:10.1063/5.0015657 .

Markushev, Dragana K., Markushev, Dragan D., Aleksić, Sanja M., Pantić, Dragan S., Galović, Slobodanka, Todorović, Dragan M., Ordonez-Miranda, Jose, "Experimental photoacoustic observation of the photogenerated excess carrier influence on the thermoelastic response of n-type silicon" in Journal of Applied Physics, 128, no. 9 (2020):095103,
https://doi.org/10.1063/5.0015657 . .

TY  - JOUR
AU  - Paraš, Smiljana
AU  - Trišić, Dijana
AU  - Mitrović Ajtić, Olivera
AU  - Prokić, Bogomir
AU  - Drobne, Damjana
AU  - Živković, Slavoljub
AU  - Jokanović, Vukoman R.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9008
AB  - Novel three-dimensional (3D) nanohydroxyapatite-PLGA scaffolds with high porosity was developed to better mimic mineral component and microstructure of natural bone. To perform a final assessment of this nanomaterial as a potential bone substitute, its toxicological profile was particularly investigated. Therefore, we performed a comet assay on human monocytes for in vitro genotoxicity investigation, and the systemic subchronic toxicity investigation on rats being per oral feed with exactly administrated extract quantities of the nano calcium hydroxyapatite covered with tiny layers of PLGA (ALBO-OS) for 120 days. Histological and stereological parameters of the liver, kidney, and spleen tissue were analyzed. Comet assay revealed low genotoxic potential, while histological analysis and stereological investigation revealed no significant changes in exposed animals when compared to controls, although the volume density of blood sinusoids and connective tissue, as well as numerical density and number of mitosis were slightly increased. Additionally, despite the significantly increased average number of the Ki67 and slightly increased number of CD68 positive cells in the presence of ALBO-OS, immunoreactive cells proliferation was almost neglected. Blood analyses showed that all of the blood parameters in rats fed with extract nanomaterial are comparable with corresponding parameters of no feed rats, taken as blind probe. This study contributes to the toxicological profiling of ALBO-OS scaffold for potential future application in bone tissue engineering.
T2  - Nanomaterials
T1  - Toxicological Profile of Nanostructured Bone Substitute Based on Hydroxyapatite and Poly(lactide-co-glycolide) after Subchronic Oral Exposure of Rats
VL  - 10
IS  - 5
SP  - 918
DO  - 10.3390/nano10050918
ER  - 

@article{
author = "Paraš, Smiljana and Trišić, Dijana and Mitrović Ajtić, Olivera and Prokić, Bogomir and Drobne, Damjana and Živković, Slavoljub and Jokanović, Vukoman R.",
year = "2020",
abstract = "Novel three-dimensional (3D) nanohydroxyapatite-PLGA scaffolds with high porosity was developed to better mimic mineral component and microstructure of natural bone. To perform a final assessment of this nanomaterial as a potential bone substitute, its toxicological profile was particularly investigated. Therefore, we performed a comet assay on human monocytes for in vitro genotoxicity investigation, and the systemic subchronic toxicity investigation on rats being per oral feed with exactly administrated extract quantities of the nano calcium hydroxyapatite covered with tiny layers of PLGA (ALBO-OS) for 120 days. Histological and stereological parameters of the liver, kidney, and spleen tissue were analyzed. Comet assay revealed low genotoxic potential, while histological analysis and stereological investigation revealed no significant changes in exposed animals when compared to controls, although the volume density of blood sinusoids and connective tissue, as well as numerical density and number of mitosis were slightly increased. Additionally, despite the significantly increased average number of the Ki67 and slightly increased number of CD68 positive cells in the presence of ALBO-OS, immunoreactive cells proliferation was almost neglected. Blood analyses showed that all of the blood parameters in rats fed with extract nanomaterial are comparable with corresponding parameters of no feed rats, taken as blind probe. This study contributes to the toxicological profiling of ALBO-OS scaffold for potential future application in bone tissue engineering.",
journal = "Nanomaterials",
title = "Toxicological Profile of Nanostructured Bone Substitute Based on Hydroxyapatite and Poly(lactide-co-glycolide) after Subchronic Oral Exposure of Rats",
volume = "10",
number = "5",
pages = "918",
doi = "10.3390/nano10050918"
}

Paraš, S., Trišić, D., Mitrović Ajtić, O., Prokić, B., Drobne, D., Živković, S.,& Jokanović, V. R.. (2020). Toxicological Profile of Nanostructured Bone Substitute Based on Hydroxyapatite and Poly(lactide-co-glycolide) after Subchronic Oral Exposure of Rats. in Nanomaterials, 10(5), 918.
https://doi.org/10.3390/nano10050918

Paraš S, Trišić D, Mitrović Ajtić O, Prokić B, Drobne D, Živković S, Jokanović VR. Toxicological Profile of Nanostructured Bone Substitute Based on Hydroxyapatite and Poly(lactide-co-glycolide) after Subchronic Oral Exposure of Rats. in Nanomaterials. 2020;10(5):918.
doi:10.3390/nano10050918 .

Paraš, Smiljana, Trišić, Dijana, Mitrović Ajtić, Olivera, Prokić, Bogomir, Drobne, Damjana, Živković, Slavoljub, Jokanović, Vukoman R., "Toxicological Profile of Nanostructured Bone Substitute Based on Hydroxyapatite and Poly(lactide-co-glycolide) after Subchronic Oral Exposure of Rats" in Nanomaterials, 10, no. 5 (2020):918,
https://doi.org/10.3390/nano10050918 . .

TY  - JOUR
AU  - Miličević, Dejan S.
AU  - Suljovrujić, Edin H.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8562
AB  - In order to investigate the resistance of poly-(l-lactide) (PLLA) to high-energy radiation, two varieties of samples with substantial differences in microstructure and crystallinity are prepared and exposed to the gamma radiation to various absorbed doses (up to 300 kGy). Since the PLLA morphology is sensitive to preparation conditions and radiation, surface microstructures are analyzed by scanning electronic microscopy. The chain scission degradation is followed using a gel permeation chromatography, while the additional characterization is conducted by differential scanning calorimetry, wide-angle X-ray diffraction method and IR spectroscopy. Presented results show that the quenched samples are more susceptible to radiation than initially high crystalline ones. Furthermore, the radiation leads to two considerably dissimilar recrystallization dynamics, connected with initial structural differences and the presence/absence of taut-tie chains. Radiation-induced increase in the crystallinity (more than 25% of initial value) for the quenched samples is noticeable at low radiation doses. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
T2  - Polymer Bulletin
T1  - The resistance of poly-(l-lactide) to gamma radiation: effect of initial preparation and crystallinity
VL  - 77
IS  - 5
SP  - 2659
EP  - 2677
DO  - 10.1007/s00289-019-02880-2
ER  - 

@article{
author = "Miličević, Dejan S. and Suljovrujić, Edin H.",
year = "2020",
abstract = "In order to investigate the resistance of poly-(l-lactide) (PLLA) to high-energy radiation, two varieties of samples with substantial differences in microstructure and crystallinity are prepared and exposed to the gamma radiation to various absorbed doses (up to 300 kGy). Since the PLLA morphology is sensitive to preparation conditions and radiation, surface microstructures are analyzed by scanning electronic microscopy. The chain scission degradation is followed using a gel permeation chromatography, while the additional characterization is conducted by differential scanning calorimetry, wide-angle X-ray diffraction method and IR spectroscopy. Presented results show that the quenched samples are more susceptible to radiation than initially high crystalline ones. Furthermore, the radiation leads to two considerably dissimilar recrystallization dynamics, connected with initial structural differences and the presence/absence of taut-tie chains. Radiation-induced increase in the crystallinity (more than 25% of initial value) for the quenched samples is noticeable at low radiation doses. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.",
journal = "Polymer Bulletin",
title = "The resistance of poly-(l-lactide) to gamma radiation: effect of initial preparation and crystallinity",
volume = "77",
number = "5",
pages = "2659-2677",
doi = "10.1007/s00289-019-02880-2"
}

Miličević, D. S.,& Suljovrujić, E. H.. (2020). The resistance of poly-(l-lactide) to gamma radiation: effect of initial preparation and crystallinity. in Polymer Bulletin, 77(5), 2659-2677.
https://doi.org/10.1007/s00289-019-02880-2

Miličević DS, Suljovrujić EH. The resistance of poly-(l-lactide) to gamma radiation: effect of initial preparation and crystallinity. in Polymer Bulletin. 2020;77(5):2659-2677.
doi:10.1007/s00289-019-02880-2 .

Miličević, Dejan S., Suljovrujić, Edin H., "The resistance of poly-(l-lactide) to gamma radiation: effect of initial preparation and crystallinity" in Polymer Bulletin, 77, no. 5 (2020):2659-2677,
https://doi.org/10.1007/s00289-019-02880-2 . .

TY  - JOUR
AU  - Čolović, Božana M.
AU  - Kisić, Danilo
AU  - Jokanović, Bojan
AU  - Rakočević, Zlatko Lj.
AU  - Nasov, Ilija
AU  - Trajkovska Petkoska, Anka
AU  - Jokanović, Vukoman R.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8350
AB  - Thin films of titanium oxides, titanium oxynitrides and titanium nitrides were deposited on glass substrates by the methods of direct current (DC) and pulsed magnetron sputtering and cathodic arc evaporation. Phase analysis of the deposited films by X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR) showed the presence of phases with various Ti oxidative states, which indicated a high concentration of oxygen vacancies. The films morphology was investigated by scanning electron microscopy (SEM). Investigations of the films wettability, either with water or ethylene glycol, showed that it depends directly on the concentration of oxygen vacancies. The wettability mechanism was particularly discussed.
T2  - Materials Science-Poland
T1  - Wetting properties of titanium oxides, oxynitrides and nitrides obtained by DC and pulsed magnetron sputtering and cathodic arc evaporation
VL  - 37
IS  - 2
SP  - 173
EP  - 181
DO  - 10.2478/msp-2019-0031
ER  - 

@article{
author = "Čolović, Božana M. and Kisić, Danilo and Jokanović, Bojan and Rakočević, Zlatko Lj. and Nasov, Ilija and Trajkovska Petkoska, Anka and Jokanović, Vukoman R.",
year = "2019",
abstract = "Thin films of titanium oxides, titanium oxynitrides and titanium nitrides were deposited on glass substrates by the methods of direct current (DC) and pulsed magnetron sputtering and cathodic arc evaporation. Phase analysis of the deposited films by X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR) showed the presence of phases with various Ti oxidative states, which indicated a high concentration of oxygen vacancies. The films morphology was investigated by scanning electron microscopy (SEM). Investigations of the films wettability, either with water or ethylene glycol, showed that it depends directly on the concentration of oxygen vacancies. The wettability mechanism was particularly discussed.",
journal = "Materials Science-Poland",
title = "Wetting properties of titanium oxides, oxynitrides and nitrides obtained by DC and pulsed magnetron sputtering and cathodic arc evaporation",
volume = "37",
number = "2",
pages = "173-181",
doi = "10.2478/msp-2019-0031"
}

Čolović, B. M., Kisić, D., Jokanović, B., Rakočević, Z. Lj., Nasov, I., Trajkovska Petkoska, A.,& Jokanović, V. R.. (2019). Wetting properties of titanium oxides, oxynitrides and nitrides obtained by DC and pulsed magnetron sputtering and cathodic arc evaporation. in Materials Science-Poland, 37(2), 173-181.
https://doi.org/10.2478/msp-2019-0031

Čolović BM, Kisić D, Jokanović B, Rakočević ZL, Nasov I, Trajkovska Petkoska A, Jokanović VR. Wetting properties of titanium oxides, oxynitrides and nitrides obtained by DC and pulsed magnetron sputtering and cathodic arc evaporation. in Materials Science-Poland. 2019;37(2):173-181.
doi:10.2478/msp-2019-0031 .

Čolović, Božana M., Kisić, Danilo, Jokanović, Bojan, Rakočević, Zlatko Lj., Nasov, Ilija, Trajkovska Petkoska, Anka, Jokanović, Vukoman R., "Wetting properties of titanium oxides, oxynitrides and nitrides obtained by DC and pulsed magnetron sputtering and cathodic arc evaporation" in Materials Science-Poland, 37, no. 2 (2019):173-181,
https://doi.org/10.2478/msp-2019-0031 . .

TY  - JOUR
AU  - Magić, Marko
AU  - Čolović, Božana M.
AU  - Jokanović, Vukoman R.
AU  - Vasilijić, Saša
AU  - Marković, Milan
AU  - Vučević, Dragana
AU  - Rudolf, Rebeka
AU  - Čolić, Snježana
AU  - Čolić, Miodrag
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8425
AB  - Background/Aim. The deposition of hydroxyapatite (HAP) on the surface of titanium (Ti) alloys enhances bioactivity and osseointegration of the alloys which are widely used as implant materials in dentistry and orthopaedic surgery. However, the stability of HAP and subsequent biocompatibility of such alloys depends on the coating technique. The aim of this work was to test the cytotoxicity of a Ti alloy (Ti6Al4V), coated with HAP by a new plasma deposition method. Methods. The Ti6Al4V samples prepared as discs, 10 mm in diameter and 2 mm in thickness, were coated with HAP (one or both sides of the alloy) by an innovative atmospheric plasma jet method. The cytotoxicity of uncoated and HAP coated Ti6Al4V samples was evaluated by examining the morphological changes and viability of L929 fibroblasts in direct contact with the test materials. Adequate negative (polystyrene) and positive (nickel) control discs of the same size were used. The indirect cytotoxicity was determined by cultivating L929 cells with conditioning medium (CM), prepared as extract of the test samples incubated in the complete Roswell Park Memorial Institute (RPMI) 1640 medium for cell cultures. The cytotoxic effect was evaluated based on the degree of metabolic activity, necrosis, apoptosis and proliferation of L929 cells, using the appropriate assays. Results. Uncoated and one side HAP coated Ti6Al4V alloys were classified as non-cytotoxic according to the current ISO 10993-5 criteria, whereas two sides HAP coated Ti6Al4V alloy samples were slightlymoderate cytotoxic. The cytotoxicity manifested as the inhibition of metabolic activity and proliferation of L929 cells as well as the induction of their apoptosis and necrosis was significantly reduced by conditioning of HAP/Ti6Al4V alloys for 24 hours. The cytotoxic effect of HAP/Ti6Al4V CM only partly decreased in the presence of nifelate, a calcium (Ca) channel blocker, suggesting that Ca ions were not the only responsible cytotoxic agent. Conclusion. The original HAP coating procedure by atmospheric plasma spraying with high energy input enables the production of the stable adhesive coatings on Ti6Al4V alloys. Their cytotoxicity, which depends on the quantity of HAP coating layer, could be significantly reduced up to the non-cytotoxic level by prior conditioning of the alloys in culture medium. Such a procedure, which removes leachable toxic components, could be useful before implantation of HAP coated alloys in vivo. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.
T2  - Vojnosanitetski pregled
T1  - Cytotoxicity of a titanium alloy coated with hydroxyapatite by plasma jet deposition
VL  - 76
IS  - 5
SP  - 492
EP  - 501
DO  - 10.2298/VSP170809097M
ER  - 

@article{
author = "Magić, Marko and Čolović, Božana M. and Jokanović, Vukoman R. and Vasilijić, Saša and Marković, Milan and Vučević, Dragana and Rudolf, Rebeka and Čolić, Snježana and Čolić, Miodrag",
year = "2019",
abstract = "Background/Aim. The deposition of hydroxyapatite (HAP) on the surface of titanium (Ti) alloys enhances bioactivity and osseointegration of the alloys which are widely used as implant materials in dentistry and orthopaedic surgery. However, the stability of HAP and subsequent biocompatibility of such alloys depends on the coating technique. The aim of this work was to test the cytotoxicity of a Ti alloy (Ti6Al4V), coated with HAP by a new plasma deposition method. Methods. The Ti6Al4V samples prepared as discs, 10 mm in diameter and 2 mm in thickness, were coated with HAP (one or both sides of the alloy) by an innovative atmospheric plasma jet method. The cytotoxicity of uncoated and HAP coated Ti6Al4V samples was evaluated by examining the morphological changes and viability of L929 fibroblasts in direct contact with the test materials. Adequate negative (polystyrene) and positive (nickel) control discs of the same size were used. The indirect cytotoxicity was determined by cultivating L929 cells with conditioning medium (CM), prepared as extract of the test samples incubated in the complete Roswell Park Memorial Institute (RPMI) 1640 medium for cell cultures. The cytotoxic effect was evaluated based on the degree of metabolic activity, necrosis, apoptosis and proliferation of L929 cells, using the appropriate assays. Results. Uncoated and one side HAP coated Ti6Al4V alloys were classified as non-cytotoxic according to the current ISO 10993-5 criteria, whereas two sides HAP coated Ti6Al4V alloy samples were slightlymoderate cytotoxic. The cytotoxicity manifested as the inhibition of metabolic activity and proliferation of L929 cells as well as the induction of their apoptosis and necrosis was significantly reduced by conditioning of HAP/Ti6Al4V alloys for 24 hours. The cytotoxic effect of HAP/Ti6Al4V CM only partly decreased in the presence of nifelate, a calcium (Ca) channel blocker, suggesting that Ca ions were not the only responsible cytotoxic agent. Conclusion. The original HAP coating procedure by atmospheric plasma spraying with high energy input enables the production of the stable adhesive coatings on Ti6Al4V alloys. Their cytotoxicity, which depends on the quantity of HAP coating layer, could be significantly reduced up to the non-cytotoxic level by prior conditioning of the alloys in culture medium. Such a procedure, which removes leachable toxic components, could be useful before implantation of HAP coated alloys in vivo. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.",
journal = "Vojnosanitetski pregled",
title = "Cytotoxicity of a titanium alloy coated with hydroxyapatite by plasma jet deposition",
volume = "76",
number = "5",
pages = "492-501",
doi = "10.2298/VSP170809097M"
}

Magić, M., Čolović, B. M., Jokanović, V. R., Vasilijić, S., Marković, M., Vučević, D., Rudolf, R., Čolić, S.,& Čolić, M.. (2019). Cytotoxicity of a titanium alloy coated with hydroxyapatite by plasma jet deposition. in Vojnosanitetski pregled, 76(5), 492-501.
https://doi.org/10.2298/VSP170809097M

Magić M, Čolović BM, Jokanović VR, Vasilijić S, Marković M, Vučević D, Rudolf R, Čolić S, Čolić M. Cytotoxicity of a titanium alloy coated with hydroxyapatite by plasma jet deposition. in Vojnosanitetski pregled. 2019;76(5):492-501.
doi:10.2298/VSP170809097M .

Magić, Marko, Čolović, Božana M., Jokanović, Vukoman R., Vasilijić, Saša, Marković, Milan, Vučević, Dragana, Rudolf, Rebeka, Čolić, Snježana, Čolić, Miodrag, "Cytotoxicity of a titanium alloy coated with hydroxyapatite by plasma jet deposition" in Vojnosanitetski pregled, 76, no. 5 (2019):492-501,
https://doi.org/10.2298/VSP170809097M . .

TY  - JOUR
AU  - Čolović, Božana M.
AU  - Janković, Ognjenka
AU  - Živković, Slavoljub
AU  - Žižak, Željko
AU  - Besu Žižak, Irina
AU  - Jokanović, Vukoman R.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8488
AB  - The synthesis of a new endodontic mixture based on calcium aluminate cement is reported. Physico-chemical and mechanical properties of the mixture were investigated before and after various hydration periods. Phase analysis of the mixture was performed using X-ray diffraction (XRD), while morphological analysis was performed by scanning electron microscopy (SEM) equipped with EDS which revealed elemental composition of the mixture sample. Investigations of mechanical properties showed that this new endodontic mixture possessed good mechanical properties (compressive strength after 28 days aging was 94 MPa) and relatively short setting time (2 h). Additionally, cytotoxicity of the mixture was investigated by MTT assay, while genotoxicity was investigated by Comet assay, using MRC-5 cell line. The obtained results make this material very promising for potential application in dental practice. © 2019 Elsevier Ltd and Techna Group S.r.l.
T2  - Ceramics International
T1  - A new endodontic mixture based on calcium aluminate cement obtained by hydrothermal synthesis
VL  - 45
IS  - 7
SP  - 9211
EP  - 9218
DO  - 10.1016/j.ceramint.2019.01.266
ER  - 

@article{
author = "Čolović, Božana M. and Janković, Ognjenka and Živković, Slavoljub and Žižak, Željko and Besu Žižak, Irina and Jokanović, Vukoman R.",
year = "2019",
abstract = "The synthesis of a new endodontic mixture based on calcium aluminate cement is reported. Physico-chemical and mechanical properties of the mixture were investigated before and after various hydration periods. Phase analysis of the mixture was performed using X-ray diffraction (XRD), while morphological analysis was performed by scanning electron microscopy (SEM) equipped with EDS which revealed elemental composition of the mixture sample. Investigations of mechanical properties showed that this new endodontic mixture possessed good mechanical properties (compressive strength after 28 days aging was 94 MPa) and relatively short setting time (2 h). Additionally, cytotoxicity of the mixture was investigated by MTT assay, while genotoxicity was investigated by Comet assay, using MRC-5 cell line. The obtained results make this material very promising for potential application in dental practice. © 2019 Elsevier Ltd and Techna Group S.r.l.",
journal = "Ceramics International",
title = "A new endodontic mixture based on calcium aluminate cement obtained by hydrothermal synthesis",
volume = "45",
number = "7",
pages = "9211-9218",
doi = "10.1016/j.ceramint.2019.01.266"
}

Čolović, B. M., Janković, O., Živković, S., Žižak, Ž., Besu Žižak, I.,& Jokanović, V. R.. (2019). A new endodontic mixture based on calcium aluminate cement obtained by hydrothermal synthesis. in Ceramics International, 45(7), 9211-9218.
https://doi.org/10.1016/j.ceramint.2019.01.266

Čolović BM, Janković O, Živković S, Žižak Ž, Besu Žižak I, Jokanović VR. A new endodontic mixture based on calcium aluminate cement obtained by hydrothermal synthesis. in Ceramics International. 2019;45(7):9211-9218.
doi:10.1016/j.ceramint.2019.01.266 .

Čolović, Božana M., Janković, Ognjenka, Živković, Slavoljub, Žižak, Željko, Besu Žižak, Irina, Jokanović, Vukoman R., "A new endodontic mixture based on calcium aluminate cement obtained by hydrothermal synthesis" in Ceramics International, 45, no. 7 (2019):9211-9218,
https://doi.org/10.1016/j.ceramint.2019.01.266 . .

TY  - JOUR
AU  - Paraš, Smiljana
AU  - Janković, Ognjenka
AU  - Trišić, Dijana
AU  - Čolović, Božana M.
AU  - Mitrović‐Ajtić, Olivera
AU  - Dekić, Radoslav
AU  - Soldatović, Ivan A.
AU  - Živković-Sandić, Marija
AU  - Živković, Slavoljub
AU  - Jokanović, Vukoman R.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8557
AB  - Aim: To examine the potential systemic toxicity of nanostructured materials based on calcium silicate and calcium aluminate, for potential application in Dentistry. Methodology: Twenty-four Albino Wistar rats aged 2 months were used as an in vivo animal model for subcutaneous implantation of the investigated materials, placed in polyethylene tubes. Thirty days after implantation, the livers of the rats were analysed and following histological and stereological parameters were evaluated for volume density of hepatocytes and blood sinusoids, number and numerical density of hepatocytes, surface of hepatocytes and their nucleuses, nucleocytoplasmic ratio and mitotic index of hepatocytes. Stereological measurements were achieved using Cavalieri's principle, with grid P2 and unbiased analysis. Additionally, immunohistochemistry studies were performed to further analyse changes in liver tissue. Several haematological and biochemical parameters of blood of experimental animals were also analysed, as well as local tissue reactions around the implants. Statistical analysis was performed using parametric (anova and t-test) and nonparametric tests (Kruskal–Wallis and Mann–Whitney U-test) depending on data distribution. Results: Implanted dental cements led to an increase in stereological and histological parameters in liver tissue compared to control rats. Although the investigated parameters mostly showed significant differences between control and experimental animals, the liver tissue of the experimental animals did not have visible signs of pathological changes. This was supported by the analysis of blood parameters which were not significantly different between control and experimental animals. Also, the subcutaneous tissues had minimal inflammatory reactions. Immunohistochemistry studies revealed that nanostructured materials induced proliferation of hepatocytes, but that the immunological response to the materials was not strong enough to induce proliferation of immunoreactive cells in liver in the observed time period. Conclusions: This study was performed as a contribution to the attestation of the biocompatibility of dental cements based on calcium silicate and calcium aluminate. Although these materials induced several changes in the liver structure, they were not clinically relevant and represent a normal and reversible response of the liver to the presence of biocompatible materials in the body. Blood and immunohistochemistry analyses and local tissue reactions further confirmed that these materials possess good biocompatible potential. © 2019 International Endodontic Journal. Published by John Wiley & Sons Ltd
T2  - International Endodontic Journal
T1  - Influence of nanostructured calcium aluminate and calcium silicate on the liver: histological and unbiased stereological analysis
SP  - 1162
EP  - 1172
DO  - 10.1111/iej.13105
ER  - 

@article{
author = "Paraš, Smiljana and Janković, Ognjenka and Trišić, Dijana and Čolović, Božana M. and Mitrović‐Ajtić, Olivera and Dekić, Radoslav and Soldatović, Ivan A. and Živković-Sandić, Marija and Živković, Slavoljub and Jokanović, Vukoman R.",
year = "2019",
abstract = "Aim: To examine the potential systemic toxicity of nanostructured materials based on calcium silicate and calcium aluminate, for potential application in Dentistry. Methodology: Twenty-four Albino Wistar rats aged 2 months were used as an in vivo animal model for subcutaneous implantation of the investigated materials, placed in polyethylene tubes. Thirty days after implantation, the livers of the rats were analysed and following histological and stereological parameters were evaluated for volume density of hepatocytes and blood sinusoids, number and numerical density of hepatocytes, surface of hepatocytes and their nucleuses, nucleocytoplasmic ratio and mitotic index of hepatocytes. Stereological measurements were achieved using Cavalieri's principle, with grid P2 and unbiased analysis. Additionally, immunohistochemistry studies were performed to further analyse changes in liver tissue. Several haematological and biochemical parameters of blood of experimental animals were also analysed, as well as local tissue reactions around the implants. Statistical analysis was performed using parametric (anova and t-test) and nonparametric tests (Kruskal–Wallis and Mann–Whitney U-test) depending on data distribution. Results: Implanted dental cements led to an increase in stereological and histological parameters in liver tissue compared to control rats. Although the investigated parameters mostly showed significant differences between control and experimental animals, the liver tissue of the experimental animals did not have visible signs of pathological changes. This was supported by the analysis of blood parameters which were not significantly different between control and experimental animals. Also, the subcutaneous tissues had minimal inflammatory reactions. Immunohistochemistry studies revealed that nanostructured materials induced proliferation of hepatocytes, but that the immunological response to the materials was not strong enough to induce proliferation of immunoreactive cells in liver in the observed time period. Conclusions: This study was performed as a contribution to the attestation of the biocompatibility of dental cements based on calcium silicate and calcium aluminate. Although these materials induced several changes in the liver structure, they were not clinically relevant and represent a normal and reversible response of the liver to the presence of biocompatible materials in the body. Blood and immunohistochemistry analyses and local tissue reactions further confirmed that these materials possess good biocompatible potential. © 2019 International Endodontic Journal. Published by John Wiley & Sons Ltd",
journal = "International Endodontic Journal",
title = "Influence of nanostructured calcium aluminate and calcium silicate on the liver: histological and unbiased stereological analysis",
pages = "1162-1172",
doi = "10.1111/iej.13105"
}

Paraš, S., Janković, O., Trišić, D., Čolović, B. M., Mitrović‐Ajtić, O., Dekić, R., Soldatović, I. A., Živković-Sandić, M., Živković, S.,& Jokanović, V. R.. (2019). Influence of nanostructured calcium aluminate and calcium silicate on the liver: histological and unbiased stereological analysis. in International Endodontic Journal, 1162-1172.
https://doi.org/10.1111/iej.13105

Paraš S, Janković O, Trišić D, Čolović BM, Mitrović‐Ajtić O, Dekić R, Soldatović IA, Živković-Sandić M, Živković S, Jokanović VR. Influence of nanostructured calcium aluminate and calcium silicate on the liver: histological and unbiased stereological analysis. in International Endodontic Journal. 2019;:1162-1172.
doi:10.1111/iej.13105 .

Paraš, Smiljana, Janković, Ognjenka, Trišić, Dijana, Čolović, Božana M., Mitrović‐Ajtić, Olivera, Dekić, Radoslav, Soldatović, Ivan A., Živković-Sandić, Marija, Živković, Slavoljub, Jokanović, Vukoman R., "Influence of nanostructured calcium aluminate and calcium silicate on the liver: histological and unbiased stereological analysis" in International Endodontic Journal (2019):1162-1172,
https://doi.org/10.1111/iej.13105 . .

TY  - JOUR
AU  - Ilić, Dragan V.
AU  - Antonijević, Đorđe
AU  - Biočanin, Vladimir
AU  - Čolović, Božana M.
AU  - Danilović, Vesna
AU  - Komlev, Vladimir
AU  - Teterina, Anastasia
AU  - Jokanović, Vukoman R.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8661
AB  - Dental cement materials have been developed with the aim to replace hard dental tissues. The first material used for pulp capping, root canal obturation, bifurcation perforation and apexification is calcium hydroxide (in 1920). A half century later, glass-ionomer cements began to suppress it as dentine substitutes. Finally, in the 1990s, calcium silicate (CS) material appeared in the dental research community as the most promising dentine substitute capable to adequately meet all clinical requirements. The aim of this paper is to present an overview of literature related to studies about CS materials taking into account their physical, chemical and biological properties and clinical applications. This review aims to discuss beneficial and adverse characteristics of CSs concerning interactions to the hard dentine and soft pulp/periodontal tissues. This review article deals with the literature data about currently commercially available CS concerning laboratory and clinical findings. 109 scientific articles were analyzed of which 62 references reported in vitro and 26 in vivo investigations while 21 references comprised reports, reviews and books dealing with both, in vitro and in vivo investigations. Although further data collection is necessary, CSs are promising materials that represent a gold standard for numerous dental clinical procedures. © 2019, Association of Chemists and Chemical Engineers of Serbia. All rights reserved.
T2  - Hemijska industrija
T1  - Physico-chemical and biological properties of dental calcium silicate cements - literature review
VL  - 73
IS  - 5
SP  - 281
EP  - 294
DO  - 10.2298/HEMIND190614027I
ER  - 

@article{
author = "Ilić, Dragan V. and Antonijević, Đorđe and Biočanin, Vladimir and Čolović, Božana M. and Danilović, Vesna and Komlev, Vladimir and Teterina, Anastasia and Jokanović, Vukoman R.",
year = "2019",
abstract = "Dental cement materials have been developed with the aim to replace hard dental tissues. The first material used for pulp capping, root canal obturation, bifurcation perforation and apexification is calcium hydroxide (in 1920). A half century later, glass-ionomer cements began to suppress it as dentine substitutes. Finally, in the 1990s, calcium silicate (CS) material appeared in the dental research community as the most promising dentine substitute capable to adequately meet all clinical requirements. The aim of this paper is to present an overview of literature related to studies about CS materials taking into account their physical, chemical and biological properties and clinical applications. This review aims to discuss beneficial and adverse characteristics of CSs concerning interactions to the hard dentine and soft pulp/periodontal tissues. This review article deals with the literature data about currently commercially available CS concerning laboratory and clinical findings. 109 scientific articles were analyzed of which 62 references reported in vitro and 26 in vivo investigations while 21 references comprised reports, reviews and books dealing with both, in vitro and in vivo investigations. Although further data collection is necessary, CSs are promising materials that represent a gold standard for numerous dental clinical procedures. © 2019, Association of Chemists and Chemical Engineers of Serbia. All rights reserved.",
journal = "Hemijska industrija",
title = "Physico-chemical and biological properties of dental calcium silicate cements - literature review",
volume = "73",
number = "5",
pages = "281-294",
doi = "10.2298/HEMIND190614027I"
}

Ilić, D. V., Antonijević, Đ., Biočanin, V., Čolović, B. M., Danilović, V., Komlev, V., Teterina, A.,& Jokanović, V. R.. (2019). Physico-chemical and biological properties of dental calcium silicate cements - literature review. in Hemijska industrija, 73(5), 281-294.
https://doi.org/10.2298/HEMIND190614027I

Ilić DV, Antonijević Đ, Biočanin V, Čolović BM, Danilović V, Komlev V, Teterina A, Jokanović VR. Physico-chemical and biological properties of dental calcium silicate cements - literature review. in Hemijska industrija. 2019;73(5):281-294.
doi:10.2298/HEMIND190614027I .

Ilić, Dragan V., Antonijević, Đorđe, Biočanin, Vladimir, Čolović, Božana M., Danilović, Vesna, Komlev, Vladimir, Teterina, Anastasia, Jokanović, Vukoman R., "Physico-chemical and biological properties of dental calcium silicate cements - literature review" in Hemijska industrija, 73, no. 5 (2019):281-294,
https://doi.org/10.2298/HEMIND190614027I . .

TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Rogić Miladinović, Zorana
AU  - Mićić, Maja M.
AU  - Suljovrujić, Denis
AU  - Miličević, Dejan S.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8048
AB  - The oligo(ethylene glycol) dimethacrylate (OEGDMA), one of the most commonly utilized crosslinking monomers, was used to tailor thermoresponsive POEGDMA hydrogels by varying the monomer/solvent feed ratio (from 10 to 100 wt% of monomer). For the first time, synthesis of different POEGDMA homopolymeric networks was performed by gamma radiation, and due to the expected thermoresponsiveness their temperature-dependent properties were extensively analysed. The sol-gel study was performed as the first step after radiation-induced synthesis. The swelling properties were investigated over the wide pH (2.2–9.0) and temperature (5–80 °C) range. Characterization of structure and properties was additionally conducted by SEM, DSC, FTIR, and UV–Vis spectroscopy. The results indicated that all POEGDMA hydrogels showed a high gel content, inverse thermoresponse and volume phase transition temperature (VPTT) with no respect to initial preparation. On the other hand, by altering the monomer/solvent ratio in the prepolymerisation mixture a large diversity in the microstructure, swelling capacity and VPTT was obtained. © 2019 Elsevier Ltd
T2  - Radiation Physics and Chemistry
T1  - The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT
VL  - 158
SP  - 37
EP  - 45
DO  - 10.1016/j.radphyschem.2018.12.034
ER  - 

@article{
author = "Suljovrujić, Edin H. and Rogić Miladinović, Zorana and Mićić, Maja M. and Suljovrujić, Denis and Miličević, Dejan S.",
year = "2019",
abstract = "The oligo(ethylene glycol) dimethacrylate (OEGDMA), one of the most commonly utilized crosslinking monomers, was used to tailor thermoresponsive POEGDMA hydrogels by varying the monomer/solvent feed ratio (from 10 to 100 wt% of monomer). For the first time, synthesis of different POEGDMA homopolymeric networks was performed by gamma radiation, and due to the expected thermoresponsiveness their temperature-dependent properties were extensively analysed. The sol-gel study was performed as the first step after radiation-induced synthesis. The swelling properties were investigated over the wide pH (2.2–9.0) and temperature (5–80 °C) range. Characterization of structure and properties was additionally conducted by SEM, DSC, FTIR, and UV–Vis spectroscopy. The results indicated that all POEGDMA hydrogels showed a high gel content, inverse thermoresponse and volume phase transition temperature (VPTT) with no respect to initial preparation. On the other hand, by altering the monomer/solvent ratio in the prepolymerisation mixture a large diversity in the microstructure, swelling capacity and VPTT was obtained. © 2019 Elsevier Ltd",
journal = "Radiation Physics and Chemistry",
title = "The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT",
volume = "158",
pages = "37-45",
doi = "10.1016/j.radphyschem.2018.12.034"
}

Suljovrujić, E. H., Rogić Miladinović, Z., Mićić, M. M., Suljovrujić, D.,& Miličević, D. S.. (2019). The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT. in Radiation Physics and Chemistry, 158, 37-45.
https://doi.org/10.1016/j.radphyschem.2018.12.034

Suljovrujić EH, Rogić Miladinović Z, Mićić MM, Suljovrujić D, Miličević DS. The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT. in Radiation Physics and Chemistry. 2019;158:37-45.
doi:10.1016/j.radphyschem.2018.12.034 .

Suljovrujić, Edin H., Rogić Miladinović, Zorana, Mićić, Maja M., Suljovrujić, Denis, Miličević, Dejan S., "The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT" in Radiation Physics and Chemistry, 158 (2019):37-45,
https://doi.org/10.1016/j.radphyschem.2018.12.034 . .

TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Rogić Miladinović, Zorana
AU  - Mićić, Maja M.
AU  - Suljovrujić, Denis
AU  - Miličević, Dejan S.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8051
AB  - The oligo(ethylene glycol) dimethacrylate (OEGDMA), one of the most commonly utilized crosslinking monomers, was used to tailor thermoresponsive POEGDMA hydrogels by varying the monomer/solvent feed ratio (from 10 to 100 wt% of monomer). For the first time, synthesis of different POEGDMA homopolymeric networks was performed by gamma radiation, and due to the expected thermoresponsiveness their temperature-dependent properties were extensively analysed. The sol-gel study was performed as the first step after radiation-induced synthesis. The swelling properties were investigated over the wide pH (2.2–9.0) and temperature (5–80 °C) range. Characterization of structure and properties was additionally conducted by SEM, DSC, FTIR, and UV–Vis spectroscopy. The results indicated that all POEGDMA hydrogels showed a high gel content, inverse thermoresponse and volume phase transition temperature (VPTT) with no respect to initial preparation. On the other hand, by altering the monomer/solvent ratio in the prepolymerisation mixture a large diversity in the microstructure, swelling capacity and VPTT was obtained. © 2019 Elsevier Ltd
T2  - Radiation Physics and Chemistry
T1  - The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT
VL  - 158
SP  - 37
EP  - 45
DO  - 10.1016/j.radphyschem.2018.12.034
ER  - 

@article{
author = "Suljovrujić, Edin H. and Rogić Miladinović, Zorana and Mićić, Maja M. and Suljovrujić, Denis and Miličević, Dejan S.",
year = "2019",
abstract = "The oligo(ethylene glycol) dimethacrylate (OEGDMA), one of the most commonly utilized crosslinking monomers, was used to tailor thermoresponsive POEGDMA hydrogels by varying the monomer/solvent feed ratio (from 10 to 100 wt% of monomer). For the first time, synthesis of different POEGDMA homopolymeric networks was performed by gamma radiation, and due to the expected thermoresponsiveness their temperature-dependent properties were extensively analysed. The sol-gel study was performed as the first step after radiation-induced synthesis. The swelling properties were investigated over the wide pH (2.2–9.0) and temperature (5–80 °C) range. Characterization of structure and properties was additionally conducted by SEM, DSC, FTIR, and UV–Vis spectroscopy. The results indicated that all POEGDMA hydrogels showed a high gel content, inverse thermoresponse and volume phase transition temperature (VPTT) with no respect to initial preparation. On the other hand, by altering the monomer/solvent ratio in the prepolymerisation mixture a large diversity in the microstructure, swelling capacity and VPTT was obtained. © 2019 Elsevier Ltd",
journal = "Radiation Physics and Chemistry",
title = "The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT",
volume = "158",
pages = "37-45",
doi = "10.1016/j.radphyschem.2018.12.034"
}

Suljovrujić, E. H., Rogić Miladinović, Z., Mićić, M. M., Suljovrujić, D.,& Miličević, D. S.. (2019). The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT. in Radiation Physics and Chemistry, 158, 37-45.
https://doi.org/10.1016/j.radphyschem.2018.12.034

Suljovrujić EH, Rogić Miladinović Z, Mićić MM, Suljovrujić D, Miličević DS. The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT. in Radiation Physics and Chemistry. 2019;158:37-45.
doi:10.1016/j.radphyschem.2018.12.034 .

Suljovrujić, Edin H., Rogić Miladinović, Zorana, Mićić, Maja M., Suljovrujić, Denis, Miličević, Dejan S., "The influence of monomer/solvent feed ratio on POEGDMA thermoresponsive hydrogels: Radiation-induced synthesis, swelling properties and VPTT" in Radiation Physics and Chemistry, 158 (2019):37-45,
https://doi.org/10.1016/j.radphyschem.2018.12.034 . .

TY  - JOUR
AU  - Trišić, Dijana
AU  - Ćetenović, Bojana
AU  - Zdravković, Nemanja M.
AU  - Marković, Tatjana
AU  - Dojčinović, Biljana P.
AU  - Jokanović, Vukoman R.
AU  - Marković, Dejan
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8426
AB  - Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA+) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the antibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA+ had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA+ in 3h and 24h of the incubation period (p < 0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA+. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.
T2  - Vojnosanitetski pregled
T1  - Antibacterial effects of new endodontic materials based on calcium silicates
VL  - 76
IS  - 4
SP  - 365
EP  - 372
DO  - 10.2298/VSP161231130T
ER  - 

@article{
author = "Trišić, Dijana and Ćetenović, Bojana and Zdravković, Nemanja M. and Marković, Tatjana and Dojčinović, Biljana P. and Jokanović, Vukoman R. and Marković, Dejan",
year = "2019",
abstract = "Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA+) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the antibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA+ had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA+ in 3h and 24h of the incubation period (p < 0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA+. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.",
journal = "Vojnosanitetski pregled",
title = "Antibacterial effects of new endodontic materials based on calcium silicates",
volume = "76",
number = "4",
pages = "365-372",
doi = "10.2298/VSP161231130T"
}

Trišić, D., Ćetenović, B., Zdravković, N. M., Marković, T., Dojčinović, B. P., Jokanović, V. R.,& Marković, D.. (2019). Antibacterial effects of new endodontic materials based on calcium silicates. in Vojnosanitetski pregled, 76(4), 365-372.
https://doi.org/10.2298/VSP161231130T

Trišić D, Ćetenović B, Zdravković NM, Marković T, Dojčinović BP, Jokanović VR, Marković D. Antibacterial effects of new endodontic materials based on calcium silicates. in Vojnosanitetski pregled. 2019;76(4):365-372.
doi:10.2298/VSP161231130T .

Trišić, Dijana, Ćetenović, Bojana, Zdravković, Nemanja M., Marković, Tatjana, Dojčinović, Biljana P., Jokanović, Vukoman R., Marković, Dejan, "Antibacterial effects of new endodontic materials based on calcium silicates" in Vojnosanitetski pregled, 76, no. 4 (2019):365-372,
https://doi.org/10.2298/VSP161231130T . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Marković, Dejan
AU  - Gutmann, James
AU  - Perić, Tamara
AU  - Jokanović, Vukoman R.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8455
AB  - Introduction/Objective The purpose of this study was to assess effectiveness of endodontic root canal procedures in traumatized permanent teeth with necrotic pulps and chronic periapical lesions after definitive obturation with mineral trioxide aggregate (MTA) products. Adobe Photoshop CS (San Jose, CA, USA) image-analysis software was used for healing assessment. Methods Twenty-seven traumatized single-rooted permanent teeth diagnosed with necrotic pulps and chronic periapical lesions were treated with non-surgical procedure using a tri-antibiotic paste and calcium hydroxide as intra-canal medication. Definitive obturation was performed with ProRoot MTA (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA) or MTA+ Cerkamed (Cerkamed, Stalowa Wola, Poland). Control follow-ups were done three, six, 12, and 24 months following the completion of treatment. Results The positive clinical outcome was recorded in 24 (88.9%) cases, while radiographic success was present in 26 (96.3%) cases. A statistically significant decrease in the sizes of periapical lesions was consistently observed at follow-up periods (p < 0.001). There was no statistically significant difference between the two tested MTA materials (p > 0.05). Conclusion The MTA products were effective for the root canal obturation and appeared to contribute to the significant reduction or complete regression of periapical lesions in teeth treated. The presented procedure may be proposed for everyday clinical practice. © 2019, Serbia Medical Society. All rights reserved.
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation - a preliminary study
VL  - 147
IS  - 5-6
SP  - 270
EP  - 275
DO  - 10.2298/SARH180301018C
ER  - 

@article{
author = "Ćetenović, Bojana and Marković, Dejan and Gutmann, James and Perić, Tamara and Jokanović, Vukoman R.",
year = "2019",
abstract = "Introduction/Objective The purpose of this study was to assess effectiveness of endodontic root canal procedures in traumatized permanent teeth with necrotic pulps and chronic periapical lesions after definitive obturation with mineral trioxide aggregate (MTA) products. Adobe Photoshop CS (San Jose, CA, USA) image-analysis software was used for healing assessment. Methods Twenty-seven traumatized single-rooted permanent teeth diagnosed with necrotic pulps and chronic periapical lesions were treated with non-surgical procedure using a tri-antibiotic paste and calcium hydroxide as intra-canal medication. Definitive obturation was performed with ProRoot MTA (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA) or MTA+ Cerkamed (Cerkamed, Stalowa Wola, Poland). Control follow-ups were done three, six, 12, and 24 months following the completion of treatment. Results The positive clinical outcome was recorded in 24 (88.9%) cases, while radiographic success was present in 26 (96.3%) cases. A statistically significant decrease in the sizes of periapical lesions was consistently observed at follow-up periods (p < 0.001). There was no statistically significant difference between the two tested MTA materials (p > 0.05). Conclusion The MTA products were effective for the root canal obturation and appeared to contribute to the significant reduction or complete regression of periapical lesions in teeth treated. The presented procedure may be proposed for everyday clinical practice. © 2019, Serbia Medical Society. All rights reserved.",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation - a preliminary study",
volume = "147",
number = "5-6",
pages = "270-275",
doi = "10.2298/SARH180301018C"
}

Ćetenović, B., Marković, D., Gutmann, J., Perić, T.,& Jokanović, V. R.. (2019). Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation - a preliminary study. in Srpski arhiv za celokupno lekarstvo, 147(5-6), 270-275.
https://doi.org/10.2298/SARH180301018C

Ćetenović B, Marković D, Gutmann J, Perić T, Jokanović VR. Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation - a preliminary study. in Srpski arhiv za celokupno lekarstvo. 2019;147(5-6):270-275.
doi:10.2298/SARH180301018C .

Ćetenović, Bojana, Marković, Dejan, Gutmann, James, Perić, Tamara, Jokanović, Vukoman R., "Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation - a preliminary study" in Srpski arhiv za celokupno lekarstvo, 147, no. 5-6 (2019):270-275,
https://doi.org/10.2298/SARH180301018C . .

TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Miličević, Dejan S.
PY  - 2019
UR  - https://www.tandfonline.com/doi/full/10.1080/1023666X.2019.1598635
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8134
AB  - Poly(l-lactide) (PLLA) is an extensively employed biodegradable semicrystalline polymer with usage from implantable medical devices and drug release matrices to environmentally friendly packaging materials. Since the morphology and crystallinity considerably determine the application field, PLLA samples with a large variation in crystallinity (going from below 20% to over 70%) were prepared by different procedures. Subsequent differences in morphology, crystallinity and thermal properties were followed by scanning electron microscopy (SEM), wide angle X-ray diffraction (WAXD) measurements and differential scanning calorimetry (DSC). The value of the enthalpy of melting of a perfectly (100%) crystalline PLLA was determined (ΔH f = 115.7 J/g). © 2019, © 2019 Taylor & Francis Group, LLC.
T2  - International Journal of Polymer Analysis and Characterization
T1  - On the enthalpy of melting of poly(l-lactide)
VL  - 24
IS  - 5
SP  - 381
EP  - 388
DO  - 10.1080/1023666X.2019.1598635
ER  - 

@article{
author = "Suljovrujić, Edin H. and Miličević, Dejan S.",
year = "2019",
abstract = "Poly(l-lactide) (PLLA) is an extensively employed biodegradable semicrystalline polymer with usage from implantable medical devices and drug release matrices to environmentally friendly packaging materials. Since the morphology and crystallinity considerably determine the application field, PLLA samples with a large variation in crystallinity (going from below 20% to over 70%) were prepared by different procedures. Subsequent differences in morphology, crystallinity and thermal properties were followed by scanning electron microscopy (SEM), wide angle X-ray diffraction (WAXD) measurements and differential scanning calorimetry (DSC). The value of the enthalpy of melting of a perfectly (100%) crystalline PLLA was determined (ΔH f = 115.7 J/g). © 2019, © 2019 Taylor & Francis Group, LLC.",
journal = "International Journal of Polymer Analysis and Characterization",
title = "On the enthalpy of melting of poly(l-lactide)",
volume = "24",
number = "5",
pages = "381-388",
doi = "10.1080/1023666X.2019.1598635"
}

Suljovrujić, E. H.,& Miličević, D. S.. (2019). On the enthalpy of melting of poly(l-lactide). in International Journal of Polymer Analysis and Characterization, 24(5), 381-388.
https://doi.org/10.1080/1023666X.2019.1598635

Suljovrujić EH, Miličević DS. On the enthalpy of melting of poly(l-lactide). in International Journal of Polymer Analysis and Characterization. 2019;24(5):381-388.
doi:10.1080/1023666X.2019.1598635 .

Suljovrujić, Edin H., Miličević, Dejan S., "On the enthalpy of melting of poly(l-lactide)" in International Journal of Polymer Analysis and Characterization, 24, no. 5 (2019):381-388,
https://doi.org/10.1080/1023666X.2019.1598635 . .

TY  - JOUR
AU  - Babić-Stojić, Branka S.
AU  - Jokanović, Vukoman R.
AU  - Milivojević, Dušan
AU  - Pozek, Miroslav
AU  - Jagličić, Zvonko
AU  - Makovec, Darko
AU  - Jović Orsini, Nataša
AU  - Marković, Mirjana
AU  - Arsikin, Katarina M.
AU  - Paunović, Verica G.
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1889
AB  - Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field from 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved.
T2  - Current Applied Physics
T1  - Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties
VL  - 18
IS  - 2
SP  - 141
EP  - 149
DO  - 10.1016/j.cap.2017.11.017
ER  - 

@article{
author = "Babić-Stojić, Branka S. and Jokanović, Vukoman R. and Milivojević, Dušan and Pozek, Miroslav and Jagličić, Zvonko and Makovec, Darko and Jović Orsini, Nataša and Marković, Mirjana and Arsikin, Katarina M. and Paunović, Verica G.",
year = "2018",
abstract = "Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field from 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved.",
journal = "Current Applied Physics",
title = "Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties",
volume = "18",
number = "2",
pages = "141-149",
doi = "10.1016/j.cap.2017.11.017"
}

Babić-Stojić, B. S., Jokanović, V. R., Milivojević, D., Pozek, M., Jagličić, Z., Makovec, D., Jović Orsini, N., Marković, M., Arsikin, K. M.,& Paunović, V. G.. (2018). Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties. in Current Applied Physics, 18(2), 141-149.
https://doi.org/10.1016/j.cap.2017.11.017

Babić-Stojić BS, Jokanović VR, Milivojević D, Pozek M, Jagličić Z, Makovec D, Jović Orsini N, Marković M, Arsikin KM, Paunović VG. Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties. in Current Applied Physics. 2018;18(2):141-149.
doi:10.1016/j.cap.2017.11.017 .

Babić-Stojić, Branka S., Jokanović, Vukoman R., Milivojević, Dušan, Pozek, Miroslav, Jagličić, Zvonko, Makovec, Darko, Jović Orsini, Nataša, Marković, Mirjana, Arsikin, Katarina M., Paunović, Verica G., "Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties" in Current Applied Physics, 18, no. 2 (2018):141-149,
https://doi.org/10.1016/j.cap.2017.11.017 . .

TY  - JOUR
AU  - Jokanović, Vukoman R.
AU  - Čolović, Božana M.
AU  - Bundaleski, Nenad
AU  - Jokanović, M.
AU  - Trajkovska Petkoska, Anka
AU  - Ferrara, Manuela
AU  - Nasov, Ilija
AU  - Rakočević, Zlatko Lj.
PY  - 2018
UR  - https://joam.inoe.ro/index.php?option=magazine&op=view&idu=4206&catid=110
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7716
AB  - Optical properties of TixOy thin film, of thickness 125 nm, obtained by pulsed magnetron sputtering were investigated in this paper. XRD analysis revealed the presence of anatase, rutile, TiO, Ti2O3and Ti3O5phases. XPS analysis showed similar results. SEM analysis showed quite smooth surface of the film. Spectroscopic ellipsometry revealed sharp decrease of refractive index in wavelength range 300-500 nm and extremely low values of extinction coefficients which are less than 0.01 at wavelengths equal to or higher than 500 nm.
T2  - Journal of Optoelectronics and Advanced Materials
T1  - TixOy thin films with extremely low extinction coefficients obtained by pulsed magnetron sputtering
VL  - 20
IS  - 3-4
SP  - 169
EP  - 174
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7716
ER  - 

@article{
author = "Jokanović, Vukoman R. and Čolović, Božana M. and Bundaleski, Nenad and Jokanović, M. and Trajkovska Petkoska, Anka and Ferrara, Manuela and Nasov, Ilija and Rakočević, Zlatko Lj.",
year = "2018",
abstract = "Optical properties of TixOy thin film, of thickness 125 nm, obtained by pulsed magnetron sputtering were investigated in this paper. XRD analysis revealed the presence of anatase, rutile, TiO, Ti2O3and Ti3O5phases. XPS analysis showed similar results. SEM analysis showed quite smooth surface of the film. Spectroscopic ellipsometry revealed sharp decrease of refractive index in wavelength range 300-500 nm and extremely low values of extinction coefficients which are less than 0.01 at wavelengths equal to or higher than 500 nm.",
journal = "Journal of Optoelectronics and Advanced Materials",
title = "TixOy thin films with extremely low extinction coefficients obtained by pulsed magnetron sputtering",
volume = "20",
number = "3-4",
pages = "169-174",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7716"
}

Jokanović, V. R., Čolović, B. M., Bundaleski, N., Jokanović, M., Trajkovska Petkoska, A., Ferrara, M., Nasov, I.,& Rakočević, Z. Lj.. (2018). TixOy thin films with extremely low extinction coefficients obtained by pulsed magnetron sputtering. in Journal of Optoelectronics and Advanced Materials, 20(3-4), 169-174.
https://hdl.handle.net/21.15107/rcub_vinar_7716

Jokanović VR, Čolović BM, Bundaleski N, Jokanović M, Trajkovska Petkoska A, Ferrara M, Nasov I, Rakočević ZL. TixOy thin films with extremely low extinction coefficients obtained by pulsed magnetron sputtering. in Journal of Optoelectronics and Advanced Materials. 2018;20(3-4):169-174.
https://hdl.handle.net/21.15107/rcub_vinar_7716 .

Jokanović, Vukoman R., Čolović, Božana M., Bundaleski, Nenad, Jokanović, M., Trajkovska Petkoska, Anka, Ferrara, Manuela, Nasov, Ilija, Rakočević, Zlatko Lj., "TixOy thin films with extremely low extinction coefficients obtained by pulsed magnetron sputtering" in Journal of Optoelectronics and Advanced Materials, 20, no. 3-4 (2018):169-174,
https://hdl.handle.net/21.15107/rcub_vinar_7716 .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Čolović, Božana M.
AU  - Vasilijić, Saša
AU  - Prokić, Bogomir
AU  - Pašalić, Snežana
AU  - Jokanović, Vukoman R.
AU  - Tepavčević, Zvezdana
AU  - Marković, Dejan
PY  - 2018
UR  - http://link.springer.com/10.1007/s10856-018-6200-z
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7990
AB  - The aim of this study was to investigate the biocompatibility of nanostructured materials based on highly active calcium silicates mixed with different radiocontrast agents in comparison to MTA+ using in vitro and in vivo model. Morphology of materials’ samples was analyzed using SEM while the phase compositions were identified by XRD. pH values of materials’ suspensions were conducted by pH-meter. The cytotoxicity of materials’ solutions was tested by MTT test (100, 50, 25 and 12.5 mg/ml). LDH and 3H-thymidine assay were utilized for biocompatibility investigations of materials’ eluates (24 h, 7 day and 21 day). Eighteen Guinea pigs were used for intramuscular implantation, as teflon tubes with freshly prepared materials were placed into intramuscular pockets. All samples were composed of round and needle-like particles equally distributed with Ca/Si ratio ~2.7 at%, with the presence of hydrated calcium silicate phases. The pH values of ALBO-MPCA1 and ALBO-MPCA2 were high alkaline, while in case of MTA+ they were lower and continuously declined (p < 0.05). Investigated materials didn’t exhibit dose-dependent effect on metabolic activity of L929 cells (p > 0.05). Significant differences in the percentage of cytotoxicity between diluted and undiluted extracts between all tested materials after 24 h and 7 day were noticed (p < 0.05). Increase in L929 cells proliferation was noticed in case of undiluted eluates of ALBO-MPCA1 and ALBO-MPCA2 after 7 day (p < 0.05). There were no statistically significant differences in the intensity of inflammatory response between investigated materials and control group after 60 day (p > 0.05). Evaluation of biocompatibility of both ALBO-MPCA1 and ALBO-MPCA2 indicate their potential clinical use. [Figure not available: see fulltext.]. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
T2  - Journal of Materials Science: Materials in Medicine
T1  - Nanostructured endodontic materials mixed with different radiocontrast agents — biocompatibility study
VL  - 29
IS  - 12
SP  - 190
DO  - 10.1007/s10856-018-6200-z
ER  - 

@article{
author = "Ćetenović, Bojana and Čolović, Božana M. and Vasilijić, Saša and Prokić, Bogomir and Pašalić, Snežana and Jokanović, Vukoman R. and Tepavčević, Zvezdana and Marković, Dejan",
year = "2018",
abstract = "The aim of this study was to investigate the biocompatibility of nanostructured materials based on highly active calcium silicates mixed with different radiocontrast agents in comparison to MTA+ using in vitro and in vivo model. Morphology of materials’ samples was analyzed using SEM while the phase compositions were identified by XRD. pH values of materials’ suspensions were conducted by pH-meter. The cytotoxicity of materials’ solutions was tested by MTT test (100, 50, 25 and 12.5 mg/ml). LDH and 3H-thymidine assay were utilized for biocompatibility investigations of materials’ eluates (24 h, 7 day and 21 day). Eighteen Guinea pigs were used for intramuscular implantation, as teflon tubes with freshly prepared materials were placed into intramuscular pockets. All samples were composed of round and needle-like particles equally distributed with Ca/Si ratio ~2.7 at%, with the presence of hydrated calcium silicate phases. The pH values of ALBO-MPCA1 and ALBO-MPCA2 were high alkaline, while in case of MTA+ they were lower and continuously declined (p < 0.05). Investigated materials didn’t exhibit dose-dependent effect on metabolic activity of L929 cells (p > 0.05). Significant differences in the percentage of cytotoxicity between diluted and undiluted extracts between all tested materials after 24 h and 7 day were noticed (p < 0.05). Increase in L929 cells proliferation was noticed in case of undiluted eluates of ALBO-MPCA1 and ALBO-MPCA2 after 7 day (p < 0.05). There were no statistically significant differences in the intensity of inflammatory response between investigated materials and control group after 60 day (p > 0.05). Evaluation of biocompatibility of both ALBO-MPCA1 and ALBO-MPCA2 indicate their potential clinical use. [Figure not available: see fulltext.]. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.",
journal = "Journal of Materials Science: Materials in Medicine",
title = "Nanostructured endodontic materials mixed with different radiocontrast agents — biocompatibility study",
volume = "29",
number = "12",
pages = "190",
doi = "10.1007/s10856-018-6200-z"
}

Ćetenović, B., Čolović, B. M., Vasilijić, S., Prokić, B., Pašalić, S., Jokanović, V. R., Tepavčević, Z.,& Marković, D.. (2018). Nanostructured endodontic materials mixed with different radiocontrast agents — biocompatibility study. in Journal of Materials Science: Materials in Medicine, 29(12), 190.
https://doi.org/10.1007/s10856-018-6200-z

Ćetenović B, Čolović BM, Vasilijić S, Prokić B, Pašalić S, Jokanović VR, Tepavčević Z, Marković D. Nanostructured endodontic materials mixed with different radiocontrast agents — biocompatibility study. in Journal of Materials Science: Materials in Medicine. 2018;29(12):190.
doi:10.1007/s10856-018-6200-z .

Ćetenović, Bojana, Čolović, Božana M., Vasilijić, Saša, Prokić, Bogomir, Pašalić, Snežana, Jokanović, Vukoman R., Tepavčević, Zvezdana, Marković, Dejan, "Nanostructured endodontic materials mixed with different radiocontrast agents — biocompatibility study" in Journal of Materials Science: Materials in Medicine, 29, no. 12 (2018):190,
https://doi.org/10.1007/s10856-018-6200-z . .

TY  - JOUR
AU  - Jokanović, Vukoman R.
AU  - Čolović, Božana M.
AU  - Prokić, Bogomir Bolka
AU  - Tomanović, Nada
AU  - Popović Bajić, Marijana
AU  - Živković, Slavoljub
PY  - 2018
UR  - https://www.hindawi.com/journals/amse/2018/8493439/
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8061
AB  - As an alternative to MTA, a new endodontic material based on hydroxyapatite and calcium silicates (ALBO-MPSA) has been synthesized, and its biocompatibility has been studied in many in vitro and in vivo studies. The current study aims to evaluate a subchronic systemic toxicity of ALBO-MPSA on the rat animal model, as a continuation of the previous studies. Biochemical parameters of blood and histological parameters of the liver, kidneys, and spleen of the rats were analyzed after 120 days of consumption of the aqueous extract of ALBO-MPSA. The results showed no myelotoxic effect or autoimmune effect on peripheral blood cells and no pathological effect on the liver, kidney, and spleen tissues. Besides, no changes in the skin and hair of the rats, neither the change in the consumption of food and water, nor the change in their usual behavior were noticed during the experiment.
T2  - Advances in Materials Science and Engineering
T1  - Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates
VL  - 2018
SP  - 1
EP  - 6
DO  - 10.1155/2018/8493439
ER  - 

@article{
author = "Jokanović, Vukoman R. and Čolović, Božana M. and Prokić, Bogomir Bolka and Tomanović, Nada and Popović Bajić, Marijana and Živković, Slavoljub",
year = "2018",
abstract = "As an alternative to MTA, a new endodontic material based on hydroxyapatite and calcium silicates (ALBO-MPSA) has been synthesized, and its biocompatibility has been studied in many in vitro and in vivo studies. The current study aims to evaluate a subchronic systemic toxicity of ALBO-MPSA on the rat animal model, as a continuation of the previous studies. Biochemical parameters of blood and histological parameters of the liver, kidneys, and spleen of the rats were analyzed after 120 days of consumption of the aqueous extract of ALBO-MPSA. The results showed no myelotoxic effect or autoimmune effect on peripheral blood cells and no pathological effect on the liver, kidney, and spleen tissues. Besides, no changes in the skin and hair of the rats, neither the change in the consumption of food and water, nor the change in their usual behavior were noticed during the experiment.",
journal = "Advances in Materials Science and Engineering",
title = "Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates",
volume = "2018",
pages = "1-6",
doi = "10.1155/2018/8493439"
}

Jokanović, V. R., Čolović, B. M., Prokić, B. B., Tomanović, N., Popović Bajić, M.,& Živković, S.. (2018). Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates. in Advances in Materials Science and Engineering, 2018, 1-6.
https://doi.org/10.1155/2018/8493439

Jokanović VR, Čolović BM, Prokić BB, Tomanović N, Popović Bajić M, Živković S. Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates. in Advances in Materials Science and Engineering. 2018;2018:1-6.
doi:10.1155/2018/8493439 .

Jokanović, Vukoman R., Čolović, Božana M., Prokić, Bogomir Bolka, Tomanović, Nada, Popović Bajić, Marijana, Živković, Slavoljub, "Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates" in Advances in Materials Science and Engineering, 2018 (2018):1-6,
https://doi.org/10.1155/2018/8493439 . .