TY  - JOUR
AU  - Milenković, Mila
AU  - Mišović, Aleksandra
AU  - Jovanović, Dragana J.
AU  - Popović-Bijelić, Ana D.
AU  - Ciasca, Gabriele
AU  - Romanò, Sabrina
AU  - Bonasera, Aurelio
AU  - Mojsin, Marija
AU  - Pejić, Jelena
AU  - Stevanović, Milena J.
AU  - Jovanović, Svetlana P.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9873
AB  - Nowadays, a larger number of aggressive and corrosive chemical reagents as well as toxic solvents are used to achieve structural modification and cleaning of the final products. These lead to the production of residual, waste chemicals, which are often reactive, cancerogenic, and toxic to the environment. This study shows a new approach to the modification of graphene quantum dots (GQDs) using gamma irradiation where the usage of reagents was avoided. We achieved the incorporation of S and N atoms in the GQD structure by selecting an aqueous solution of L-cysteine as an irradiation medium. GQDs were exposed to gamma-irradiation at doses of 25, 50 and 200 kGy. After irradiation, the optical, structural, and morphological properties, as well as the possibility of their use as an agent in bioimaging and photodynamic therapy, were studied. We measured an enhanced quantum yield of photoluminescence with the highest dose of 25 kGy (21.60%). Both S- and N-functional groups were detected in all gamma-irradiated GQDs: amino, amide, thiol, and thione. Spin trap electron paramagnetic resonance showed that GQDs irradiated with 25 kGy can generate singlet oxygen upon illumination. Bioimaging on HeLa cells showed the best visibility for cells treated with GQDs irradiated with 25 kGy, while cytotoxicity was not detected after treatment of HeLa cells with gamma-irradiated GQDs.
T2  - Nanomaterials
T1  - Facile synthesis of L-cysteine functionalized graphene quantum dots as a bioimaging and photosensitive agent
VL  - 11
IS  - 8
SP  - 1879
DO  - 10.3390/nano11081879
ER  - 

@article{
author = "Milenković, Mila and Mišović, Aleksandra and Jovanović, Dragana J. and Popović-Bijelić, Ana D. and Ciasca, Gabriele and Romanò, Sabrina and Bonasera, Aurelio and Mojsin, Marija and Pejić, Jelena and Stevanović, Milena J. and Jovanović, Svetlana P.",
year = "2021",
abstract = "Nowadays, a larger number of aggressive and corrosive chemical reagents as well as toxic solvents are used to achieve structural modification and cleaning of the final products. These lead to the production of residual, waste chemicals, which are often reactive, cancerogenic, and toxic to the environment. This study shows a new approach to the modification of graphene quantum dots (GQDs) using gamma irradiation where the usage of reagents was avoided. We achieved the incorporation of S and N atoms in the GQD structure by selecting an aqueous solution of L-cysteine as an irradiation medium. GQDs were exposed to gamma-irradiation at doses of 25, 50 and 200 kGy. After irradiation, the optical, structural, and morphological properties, as well as the possibility of their use as an agent in bioimaging and photodynamic therapy, were studied. We measured an enhanced quantum yield of photoluminescence with the highest dose of 25 kGy (21.60%). Both S- and N-functional groups were detected in all gamma-irradiated GQDs: amino, amide, thiol, and thione. Spin trap electron paramagnetic resonance showed that GQDs irradiated with 25 kGy can generate singlet oxygen upon illumination. Bioimaging on HeLa cells showed the best visibility for cells treated with GQDs irradiated with 25 kGy, while cytotoxicity was not detected after treatment of HeLa cells with gamma-irradiated GQDs.",
journal = "Nanomaterials",
title = "Facile synthesis of L-cysteine functionalized graphene quantum dots as a bioimaging and photosensitive agent",
volume = "11",
number = "8",
pages = "1879",
doi = "10.3390/nano11081879"
}

Milenković, M., Mišović, A., Jovanović, D. J., Popović-Bijelić, A. D., Ciasca, G., Romanò, S., Bonasera, A., Mojsin, M., Pejić, J., Stevanović, M. J.,& Jovanović, S. P.. (2021). Facile synthesis of L-cysteine functionalized graphene quantum dots as a bioimaging and photosensitive agent. in Nanomaterials, 11(8), 1879.
https://doi.org/10.3390/nano11081879

Milenković M, Mišović A, Jovanović DJ, Popović-Bijelić AD, Ciasca G, Romanò S, Bonasera A, Mojsin M, Pejić J, Stevanović MJ, Jovanović SP. Facile synthesis of L-cysteine functionalized graphene quantum dots as a bioimaging and photosensitive agent. in Nanomaterials. 2021;11(8):1879.
doi:10.3390/nano11081879 .

Milenković, Mila, Mišović, Aleksandra, Jovanović, Dragana J., Popović-Bijelić, Ana D., Ciasca, Gabriele, Romanò, Sabrina, Bonasera, Aurelio, Mojsin, Marija, Pejić, Jelena, Stevanović, Milena J., Jovanović, Svetlana P., "Facile synthesis of L-cysteine functionalized graphene quantum dots as a bioimaging and photosensitive agent" in Nanomaterials, 11, no. 8 (2021):1879,
https://doi.org/10.3390/nano11081879 . .

TY  - JOUR
AU  - Matijević, Milica
AU  - Nakarada, Đura
AU  - Liang, Xinyue
AU  - Korićanac, Lela
AU  - Rajsiglova, Lenka
AU  - Vannucci, Luca
AU  - Nešić, Maja D.
AU  - Vranješ, Mila
AU  - Mojović, Miloš D.
AU  - Mi, Lan
AU  - Estrela-Lopis, Irina
AU  - Böttner, Julia
AU  - Šaponjić, Zoran
AU  - Petković, Marijana
AU  - Stepić, Milutin
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9058
AB  - TiO2 prolatenanospheroids (PNSs) may be photosensitizers (PSs), which act by catalyzation of hydroxyl radical (∙OH) formation upon light illumination. ∙OH might, in turn, contribute to killing of cancer cells. On the other hand, there is great concern about toxicity in the dark of TiO2 nanoparticles in general. In this work, we have investigated the biocompatibility of TiO2 PNSs of the anatase crystal form (length between 100 and 300 nm and width 50 nm) in the dark with immune cells and light-induced cytotoxicity on several cancer cell lines. The effects of the treatment of different cell lines with several concentrations of TiO2 PNSs suspensions showed the specifics of cells’ viability and the intracellular localization. The results of in vitro studies obtained by cytotoxicity assays adjusted to individual cell lines’ metabolism point towards the biocompatibility of TiO2 PNSs at low and moderate concentrations in the dark, which neither kill the cells, nor induce activation of the immune system cells. Laser scanning confocal microscopy revealed that PNSs are taken up by cells, and insight into the intracellular distribution was obtained in this study.
T2  - Journal of Nanoparticle Research
T1  - Biocompatibility of TiO2 prolate nanospheroids as a potential photosenzitizer in therapy of cancer
VL  - 22
IS  - 7
SP  - 175
DO  - 10.1007/s11051-020-04899-3
ER  - 

@article{
author = "Matijević, Milica and Nakarada, Đura and Liang, Xinyue and Korićanac, Lela and Rajsiglova, Lenka and Vannucci, Luca and Nešić, Maja D. and Vranješ, Mila and Mojović, Miloš D. and Mi, Lan and Estrela-Lopis, Irina and Böttner, Julia and Šaponjić, Zoran and Petković, Marijana and Stepić, Milutin",
year = "2020",
abstract = "TiO2 prolatenanospheroids (PNSs) may be photosensitizers (PSs), which act by catalyzation of hydroxyl radical (∙OH) formation upon light illumination. ∙OH might, in turn, contribute to killing of cancer cells. On the other hand, there is great concern about toxicity in the dark of TiO2 nanoparticles in general. In this work, we have investigated the biocompatibility of TiO2 PNSs of the anatase crystal form (length between 100 and 300 nm and width 50 nm) in the dark with immune cells and light-induced cytotoxicity on several cancer cell lines. The effects of the treatment of different cell lines with several concentrations of TiO2 PNSs suspensions showed the specifics of cells’ viability and the intracellular localization. The results of in vitro studies obtained by cytotoxicity assays adjusted to individual cell lines’ metabolism point towards the biocompatibility of TiO2 PNSs at low and moderate concentrations in the dark, which neither kill the cells, nor induce activation of the immune system cells. Laser scanning confocal microscopy revealed that PNSs are taken up by cells, and insight into the intracellular distribution was obtained in this study.",
journal = "Journal of Nanoparticle Research",
title = "Biocompatibility of TiO2 prolate nanospheroids as a potential photosenzitizer in therapy of cancer",
volume = "22",
number = "7",
pages = "175",
doi = "10.1007/s11051-020-04899-3"
}

Matijević, M., Nakarada, Đ., Liang, X., Korićanac, L., Rajsiglova, L., Vannucci, L., Nešić, M. D., Vranješ, M., Mojović, M. D., Mi, L., Estrela-Lopis, I., Böttner, J., Šaponjić, Z., Petković, M.,& Stepić, M.. (2020). Biocompatibility of TiO2 prolate nanospheroids as a potential photosenzitizer in therapy of cancer. in Journal of Nanoparticle Research, 22(7), 175.
https://doi.org/10.1007/s11051-020-04899-3

Matijević M, Nakarada Đ, Liang X, Korićanac L, Rajsiglova L, Vannucci L, Nešić MD, Vranješ M, Mojović MD, Mi L, Estrela-Lopis I, Böttner J, Šaponjić Z, Petković M, Stepić M. Biocompatibility of TiO2 prolate nanospheroids as a potential photosenzitizer in therapy of cancer. in Journal of Nanoparticle Research. 2020;22(7):175.
doi:10.1007/s11051-020-04899-3 .

Matijević, Milica, Nakarada, Đura, Liang, Xinyue, Korićanac, Lela, Rajsiglova, Lenka, Vannucci, Luca, Nešić, Maja D., Vranješ, Mila, Mojović, Miloš D., Mi, Lan, Estrela-Lopis, Irina, Böttner, Julia, Šaponjić, Zoran, Petković, Marijana, Stepić, Milutin, "Biocompatibility of TiO2 prolate nanospheroids as a potential photosenzitizer in therapy of cancer" in Journal of Nanoparticle Research, 22, no. 7 (2020):175,
https://doi.org/10.1007/s11051-020-04899-3 . .

TY  - JOUR
AU  - Mojović, Zorica D.
AU  - Novaković, Tatjana
AU  - Mojović, Miloš D.
AU  - Barudžija, Tanja
AU  - Mitrić, Miodrag
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8596
AB  - Alumina powders, pure and doped with nickel, were synthetized by sol-gel method and calcined at 500, 900 and 1100oC in order to obtain mesoporous structures with a high specific surface area, well adapTab. to catalytic application. The characterization of samples was performed by XRD, EPR spectroscopy and electrochemical impedance spectroscopy (EIS). XRD analysis showed that the addition of Ni2+, as well as the annealing temperature, affects the structural properties of the obtained composites. EPR analysis revealed the traces of Fe3+ impurities, the presence of oxy defects in alumina and Ni2+ in tetrahedral position for samples calcined at 1100oC. The impedance of the Nafion/alumina modified GCE depended on combined effect of porous structure and surface properties of alumina samples. The electrochemical behavior of a glassy carbon electrode modified with Ni (II)-doped aluminas was studied in 0.5 M NaOH solution, with and without methanol. The electrochemical activity of nickel-doped alumina composites was dictated by the amount of present NiO impurity.
T2  - Science of Sintering
T1  - Electrochemical and structural properties of Ni(II)-alumina composites as an annealing temperature function
VL  - 51
IS  - 3
SP  - 339
EP  - 351
DO  - 10.2298/SOS1903339M
ER  - 

@article{
author = "Mojović, Zorica D. and Novaković, Tatjana and Mojović, Miloš D. and Barudžija, Tanja and Mitrić, Miodrag",
year = "2019",
abstract = "Alumina powders, pure and doped with nickel, were synthetized by sol-gel method and calcined at 500, 900 and 1100oC in order to obtain mesoporous structures with a high specific surface area, well adapTab. to catalytic application. The characterization of samples was performed by XRD, EPR spectroscopy and electrochemical impedance spectroscopy (EIS). XRD analysis showed that the addition of Ni2+, as well as the annealing temperature, affects the structural properties of the obtained composites. EPR analysis revealed the traces of Fe3+ impurities, the presence of oxy defects in alumina and Ni2+ in tetrahedral position for samples calcined at 1100oC. The impedance of the Nafion/alumina modified GCE depended on combined effect of porous structure and surface properties of alumina samples. The electrochemical behavior of a glassy carbon electrode modified with Ni (II)-doped aluminas was studied in 0.5 M NaOH solution, with and without methanol. The electrochemical activity of nickel-doped alumina composites was dictated by the amount of present NiO impurity.",
journal = "Science of Sintering",
title = "Electrochemical and structural properties of Ni(II)-alumina composites as an annealing temperature function",
volume = "51",
number = "3",
pages = "339-351",
doi = "10.2298/SOS1903339M"
}

Mojović, Z. D., Novaković, T., Mojović, M. D., Barudžija, T.,& Mitrić, M.. (2019). Electrochemical and structural properties of Ni(II)-alumina composites as an annealing temperature function. in Science of Sintering, 51(3), 339-351.
https://doi.org/10.2298/SOS1903339M

Mojović ZD, Novaković T, Mojović MD, Barudžija T, Mitrić M. Electrochemical and structural properties of Ni(II)-alumina composites as an annealing temperature function. in Science of Sintering. 2019;51(3):339-351.
doi:10.2298/SOS1903339M .

Mojović, Zorica D., Novaković, Tatjana, Mojović, Miloš D., Barudžija, Tanja, Mitrić, Miodrag, "Electrochemical and structural properties of Ni(II)-alumina composites as an annealing temperature function" in Science of Sintering, 51, no. 3 (2019):339-351,
https://doi.org/10.2298/SOS1903339M . .

TY  - JOUR
AU  - Jović-Jovičić, Nataša P.
AU  - Mojović, Miloš D.
AU  - Stanković, Dalibor M.
AU  - Vasiljević-Nedić, Bojana
AU  - Milutinović-Nikolić, Aleksandra D.
AU  - Banković, Predrag T.
AU  - Mojović, Zorica D.
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0013468618325039
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7979
AB  - Series of alkylammonium modified smectites with different alkylammoinum/clay ratios was synthesized (H series). The obtained organoclays were used as precursors for carbon-clay composite materials (C series). Both set of materials were characterized by X-ray diffraction (XRD), point of zero charge (pHPZC), N2 adsorption-desorption isotherms, Raman spectroscopy and electron paramagnetic resonance (EPR) analysis. XRD analysis of organomodified clays confirmed incorporation of HDTMA+ into interlamellar space of smectite. Series of carbonized clays showed constant d001 value of 1.4 nm. The pHPZC of two series differed indicating that carbonization changed the profile of pH dependent sites on the clay surface. Textural properties of the H series decreased throughout the series, while in the C series the most developed porous structure was obtained for sample where HDTMA+ loading was equal to cation exchange capacity. Raman spectroscopy showed that amorphous carbon was formed during carbonization process. The obtained materials were used as modifiers of carbon paste electrode and investigated using electrochemical impedance spectroscopy, cyclic voltammetry and square wave voltammetry. The comparison of electrochemical behavior of H series and C series showed the importance of interlamellar species for charge transfer process. The investigation of influence of composition of carbon paste and form of added carbon showed that performance of carbon-clay based electrodes depended on synergy of different factors. © 2018 Elsevier Ltd
T2  - Electrochimica Acta
T1  - Characterization and electrochemical properties of organomodified and corresponding derived carbonized clay
VL  - 296
SP  - 387
EP  - 396
DO  - 10.1016/j.electacta.2018.11.031
ER  - 

@article{
author = "Jović-Jovičić, Nataša P. and Mojović, Miloš D. and Stanković, Dalibor M. and Vasiljević-Nedić, Bojana and Milutinović-Nikolić, Aleksandra D. and Banković, Predrag T. and Mojović, Zorica D.",
year = "2019",
abstract = "Series of alkylammonium modified smectites with different alkylammoinum/clay ratios was synthesized (H series). The obtained organoclays were used as precursors for carbon-clay composite materials (C series). Both set of materials were characterized by X-ray diffraction (XRD), point of zero charge (pHPZC), N2 adsorption-desorption isotherms, Raman spectroscopy and electron paramagnetic resonance (EPR) analysis. XRD analysis of organomodified clays confirmed incorporation of HDTMA+ into interlamellar space of smectite. Series of carbonized clays showed constant d001 value of 1.4 nm. The pHPZC of two series differed indicating that carbonization changed the profile of pH dependent sites on the clay surface. Textural properties of the H series decreased throughout the series, while in the C series the most developed porous structure was obtained for sample where HDTMA+ loading was equal to cation exchange capacity. Raman spectroscopy showed that amorphous carbon was formed during carbonization process. The obtained materials were used as modifiers of carbon paste electrode and investigated using electrochemical impedance spectroscopy, cyclic voltammetry and square wave voltammetry. The comparison of electrochemical behavior of H series and C series showed the importance of interlamellar species for charge transfer process. The investigation of influence of composition of carbon paste and form of added carbon showed that performance of carbon-clay based electrodes depended on synergy of different factors. © 2018 Elsevier Ltd",
journal = "Electrochimica Acta",
title = "Characterization and electrochemical properties of organomodified and corresponding derived carbonized clay",
volume = "296",
pages = "387-396",
doi = "10.1016/j.electacta.2018.11.031"
}

Jović-Jovičić, N. P., Mojović, M. D., Stanković, D. M., Vasiljević-Nedić, B., Milutinović-Nikolić, A. D., Banković, P. T.,& Mojović, Z. D.. (2019). Characterization and electrochemical properties of organomodified and corresponding derived carbonized clay. in Electrochimica Acta, 296, 387-396.
https://doi.org/10.1016/j.electacta.2018.11.031

Jović-Jovičić NP, Mojović MD, Stanković DM, Vasiljević-Nedić B, Milutinović-Nikolić AD, Banković PT, Mojović ZD. Characterization and electrochemical properties of organomodified and corresponding derived carbonized clay. in Electrochimica Acta. 2019;296:387-396.
doi:10.1016/j.electacta.2018.11.031 .

Jović-Jovičić, Nataša P., Mojović, Miloš D., Stanković, Dalibor M., Vasiljević-Nedić, Bojana, Milutinović-Nikolić, Aleksandra D., Banković, Predrag T., Mojović, Zorica D., "Characterization and electrochemical properties of organomodified and corresponding derived carbonized clay" in Electrochimica Acta, 296 (2019):387-396,
https://doi.org/10.1016/j.electacta.2018.11.031 . .

TY  - JOUR
AU  - Tanić, Milan N.
AU  - Janković Mandić, Ljiljana
AU  - Gajić, Boško A.
AU  - Daković, Marko Z.
AU  - Dragović, Snežana D.
AU  - Bačić, Goran G..
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1314
AB  - This study evaluates the influence of the largest Serbian coal-fired power plant on radionuclide concentrations in soil profiles up to 50 cm in depth. Thirty soil profiles were sampled from the plant surroundings (up to 10 km distance) and analyzed using standard methods for soil physicochemical properties and gamma ray spectrometry for specific activities of natural radionuclides (K-40, Ra-226 and Th-232) Spatial and vertical distribution of radionuclides was determined and analyzed to show the relations between the specific activities in the soil and soil properties and the most influential factors of natural radionuclide variability were identified. The radiological indices for surface soil were calculated and radiological risk assessment was performed. The measured specific activities were similar to values of background levels for Serbia. The sampling depth did not show any significant influence on specific activities of natural radionuclides. The strongest predictor of specific activities of the investigated radionuclides was soil granulometry. All parameters of radiological risk assessment were below the recommended values and adopted limits. It appears that the coal-fired power plant does not have a significant impact on the spatial and vertical distribution of natural radionuclides in the area of interest, but technologically enhanced natural radioactivity as a consequence of the plant operations was identified within the first 1.5 km from the power plant.
T2  - Nuclear technology and radiation protection
T1  - Natural Radionuclides in Soil Profiles Surrounding the Largest Coal-Fired Power Plant in Serbia
VL  - 31
IS  - 3
SP  - 247
EP  - 259
DO  - 10.2298/NTRP1603247T
ER  - 

@article{
author = "Tanić, Milan N. and Janković Mandić, Ljiljana and Gajić, Boško A. and Daković, Marko Z. and Dragović, Snežana D. and Bačić, Goran G..",
year = "2016",
abstract = "This study evaluates the influence of the largest Serbian coal-fired power plant on radionuclide concentrations in soil profiles up to 50 cm in depth. Thirty soil profiles were sampled from the plant surroundings (up to 10 km distance) and analyzed using standard methods for soil physicochemical properties and gamma ray spectrometry for specific activities of natural radionuclides (K-40, Ra-226 and Th-232) Spatial and vertical distribution of radionuclides was determined and analyzed to show the relations between the specific activities in the soil and soil properties and the most influential factors of natural radionuclide variability were identified. The radiological indices for surface soil were calculated and radiological risk assessment was performed. The measured specific activities were similar to values of background levels for Serbia. The sampling depth did not show any significant influence on specific activities of natural radionuclides. The strongest predictor of specific activities of the investigated radionuclides was soil granulometry. All parameters of radiological risk assessment were below the recommended values and adopted limits. It appears that the coal-fired power plant does not have a significant impact on the spatial and vertical distribution of natural radionuclides in the area of interest, but technologically enhanced natural radioactivity as a consequence of the plant operations was identified within the first 1.5 km from the power plant.",
journal = "Nuclear technology and radiation protection",
title = "Natural Radionuclides in Soil Profiles Surrounding the Largest Coal-Fired Power Plant in Serbia",
volume = "31",
number = "3",
pages = "247-259",
doi = "10.2298/NTRP1603247T"
}

Tanić, M. N., Janković Mandić, L., Gajić, B. A., Daković, M. Z., Dragović, S. D.,& Bačić, G. G... (2016). Natural Radionuclides in Soil Profiles Surrounding the Largest Coal-Fired Power Plant in Serbia. in Nuclear technology and radiation protection, 31(3), 247-259.
https://doi.org/10.2298/NTRP1603247T

Tanić MN, Janković Mandić L, Gajić BA, Daković MZ, Dragović SD, Bačić GG. Natural Radionuclides in Soil Profiles Surrounding the Largest Coal-Fired Power Plant in Serbia. in Nuclear technology and radiation protection. 2016;31(3):247-259.
doi:10.2298/NTRP1603247T .

Tanić, Milan N., Janković Mandić, Ljiljana, Gajić, Boško A., Daković, Marko Z., Dragović, Snežana D., Bačić, Goran G.., "Natural Radionuclides in Soil Profiles Surrounding the Largest Coal-Fired Power Plant in Serbia" in Nuclear technology and radiation protection, 31, no. 3 (2016):247-259,
https://doi.org/10.2298/NTRP1603247T . .

TY  - CONF
AU  - Jovanović, M.
AU  - Šećerov, Bojana
AU  - Bačić, Goran
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9212
AB  - We  investigated  the  potential  of in  vivoelectron  paramagnetic  resonance (EPR)  in  assessingchemical  reactions  that  occur  during  ionizing  irradiation and  capabilities  of  two  radioprotectors  (an  antibiotic,  anisomycin  and  a naturally  occurring  tiol,  Gl2011)  to  enhance  survival  during  irradiation. Radioprotectors selected are supposed to have different modes of action and in vivoEPR was used to assess whether free radical scavenging has arole in their  action  as  radioprotectors.  Both  compounds  exhibited  similar  and highly   efficient   radioprotective   capabilities   according   to   the   30-days survival  test  (96%  and  87%,  respectively  after  the  dose  of  6.7  Gy). In  vivoEPR showed that free radical scavenging has an important role in the action of  GL2011,  but  not  in  the  case  of  anisomycin.  In  conclusion,  EPR  have unique  capabilities  in  studying  free  radicals in  vivoand  can  beuseful addition to battery of methods needed to study radioprotectorsin vivo.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry
T1  - The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection
SP  - 491
EP  - 494
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9212
ER  - 

@conference{
author = "Jovanović, M. and Šećerov, Bojana and Bačić, Goran",
year = "2016",
abstract = "We  investigated  the  potential  of in  vivoelectron  paramagnetic  resonance (EPR)  in  assessingchemical  reactions  that  occur  during  ionizing  irradiation and  capabilities  of  two  radioprotectors  (an  antibiotic,  anisomycin  and  a naturally  occurring  tiol,  Gl2011)  to  enhance  survival  during  irradiation. Radioprotectors selected are supposed to have different modes of action and in vivoEPR was used to assess whether free radical scavenging has arole in their  action  as  radioprotectors.  Both  compounds  exhibited  similar  and highly   efficient   radioprotective   capabilities   according   to   the   30-days survival  test  (96%  and  87%,  respectively  after  the  dose  of  6.7  Gy). In  vivoEPR showed that free radical scavenging has an important role in the action of  GL2011,  but  not  in  the  case  of  anisomycin.  In  conclusion,  EPR  have unique  capabilities  in  studying  free  radicals in  vivoand  can  beuseful addition to battery of methods needed to study radioprotectorsin vivo.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry",
title = "The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection",
pages = "491-494",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9212"
}

Jovanović, M., Šećerov, B.,& Bačić, G.. (2016). The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection. in Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia., 491-494.
https://hdl.handle.net/21.15107/rcub_vinar_9212

Jovanović M, Šećerov B, Bačić G. The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection. in Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry. 2016;:491-494.
https://hdl.handle.net/21.15107/rcub_vinar_9212 .

Jovanović, M., Šećerov, Bojana, Bačić, Goran, "The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection" in Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry (2016):491-494,
https://hdl.handle.net/21.15107/rcub_vinar_9212 .

TY  - JOUR
AU  - Okić-Đorđević, Ivana
AU  - Trivanović, Drenka
AU  - Jovanović, Miloš
AU  - Ignjatović, Marija
AU  - Šećerov, Bojana Lj.
AU  - Mojovic, Milos
AU  - Bugarski, Diana
AU  - Bačić, Goran
AU  - Anđus, Pavle R.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5935
AB  - Aim To investigate the survival of laboratory rats after irradiation and to study the cellularity of their bone marrow and the multipotential mesenchymal stem cells (BM-MSCs) in groups treated with or without a new thiol-based radioprotector (GM2011) Methods Animals were irradiated by a Cobalt gamma source at 6.7 Gy. Treated animals were given i.p. GM2011 30 minutes before and 3 and 7 hours after irradiation. Controls consisted of sham irradiated animals without treatment and animals treated without irradiation. After 30 days post-irradiation, animals were sacrificed and bone marrow cells were prepared from isolated femurs. A colony forming unit-fibroblast (CFU-F) assay was performed to obtain the number of BM-MSCs. Results In the treated group, 87% of animals survived, compared to only 30% in the non-treated irradiated group. Irradiation induced significant changes in the bone marrow of the treated rats (total bone marrow cellularity was reduced by similar to 60% - from 63 to 28 cells x10(6)/femur and the frequency of the CFU-F per femur by similar to 70% - from 357 to 97), however GL2011 almost completely prevented the suppressive effect observed on day 30 post-irradiation (71 cells x 10(6)/femur and 230 CFU-F/femur). Conclusion Although the irradiation dosage was relatively high, GL2011 acted as a very effective new radioprotector. The recovery of the BN-MSCs and their counts support the effectiveness of the studied radioprotector.
T2  - Croatian Medical Journal
T1  - Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector
VL  - 55
IS  - 1
SP  - 45
EP  - 49
DO  - 10.3325/cmj.2014.55.45
ER  - 

@article{
author = "Okić-Đorđević, Ivana and Trivanović, Drenka and Jovanović, Miloš and Ignjatović, Marija and Šećerov, Bojana Lj. and Mojovic, Milos and Bugarski, Diana and Bačić, Goran and Anđus, Pavle R.",
year = "2014",
abstract = "Aim To investigate the survival of laboratory rats after irradiation and to study the cellularity of their bone marrow and the multipotential mesenchymal stem cells (BM-MSCs) in groups treated with or without a new thiol-based radioprotector (GM2011) Methods Animals were irradiated by a Cobalt gamma source at 6.7 Gy. Treated animals were given i.p. GM2011 30 minutes before and 3 and 7 hours after irradiation. Controls consisted of sham irradiated animals without treatment and animals treated without irradiation. After 30 days post-irradiation, animals were sacrificed and bone marrow cells were prepared from isolated femurs. A colony forming unit-fibroblast (CFU-F) assay was performed to obtain the number of BM-MSCs. Results In the treated group, 87% of animals survived, compared to only 30% in the non-treated irradiated group. Irradiation induced significant changes in the bone marrow of the treated rats (total bone marrow cellularity was reduced by similar to 60% - from 63 to 28 cells x10(6)/femur and the frequency of the CFU-F per femur by similar to 70% - from 357 to 97), however GL2011 almost completely prevented the suppressive effect observed on day 30 post-irradiation (71 cells x 10(6)/femur and 230 CFU-F/femur). Conclusion Although the irradiation dosage was relatively high, GL2011 acted as a very effective new radioprotector. The recovery of the BN-MSCs and their counts support the effectiveness of the studied radioprotector.",
journal = "Croatian Medical Journal",
title = "Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector",
volume = "55",
number = "1",
pages = "45-49",
doi = "10.3325/cmj.2014.55.45"
}

Okić-Đorđević, I., Trivanović, D., Jovanović, M., Ignjatović, M., Šećerov, B. Lj., Mojovic, M., Bugarski, D., Bačić, G.,& Anđus, P. R.. (2014). Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector. in Croatian Medical Journal, 55(1), 45-49.
https://doi.org/10.3325/cmj.2014.55.45

Okić-Đorđević I, Trivanović D, Jovanović M, Ignjatović M, Šećerov BL, Mojovic M, Bugarski D, Bačić G, Anđus PR. Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector. in Croatian Medical Journal. 2014;55(1):45-49.
doi:10.3325/cmj.2014.55.45 .

Okić-Đorđević, Ivana, Trivanović, Drenka, Jovanović, Miloš, Ignjatović, Marija, Šećerov, Bojana Lj., Mojovic, Milos, Bugarski, Diana, Bačić, Goran, Anđus, Pavle R., "Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector" in Croatian Medical Journal, 55, no. 1 (2014):45-49,
https://doi.org/10.3325/cmj.2014.55.45 . .

TY  - JOUR
AU  - Momčilović, Milan
AU  - Kovačević, Jovan
AU  - Tanić, Milan
AU  - Đorđević, Milan
AU  - Bačić, Goran
AU  - Dragović, Snežana D.
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11157
AB  - The activity concentrations of natural radionuclides in soils from the area affected by uranium mining at Stara Planina Mountain in Serbia were studied and compared with the results obtained from an area with no mining activities (background area). In the affected area, the activity concentrations ranged from 1.75 to 19.2 mg kg−1 for uranium and from 1.57 to 26.9 mg kg−1 for thorium which is several-fold higher than those in the background area. The Th/U, K/U, and K/Th activity ratios were also determined and compared with data from similar studies worldwide. External gamma dose rate in the air due to uranium, thorium, and potassium at 1 m above ground level in the area affected by uranium mining was found to be 91.3 nGy h−1, i.e., about two-fold higher than that in background area. The results of this preliminary study indicate the importance of radiological evaluation of the area and implementation of remedial measures in order to prevent further dispersion of radionuclides in the environment.
T2  - Environmental Monitoring and Assessment
T1  - Distribution of natural radionuclides in surface soils in the vicinity of abandoned uranium mines in Serbia
VL  - 185
IS  - 2
SP  - 1319
EP  - 1329
DO  - 10.1007/s10661-012-2634-9
ER  - 

@article{
author = "Momčilović, Milan and Kovačević, Jovan and Tanić, Milan and Đorđević, Milan and Bačić, Goran and Dragović, Snežana D.",
year = "2013",
abstract = "The activity concentrations of natural radionuclides in soils from the area affected by uranium mining at Stara Planina Mountain in Serbia were studied and compared with the results obtained from an area with no mining activities (background area). In the affected area, the activity concentrations ranged from 1.75 to 19.2 mg kg−1 for uranium and from 1.57 to 26.9 mg kg−1 for thorium which is several-fold higher than those in the background area. The Th/U, K/U, and K/Th activity ratios were also determined and compared with data from similar studies worldwide. External gamma dose rate in the air due to uranium, thorium, and potassium at 1 m above ground level in the area affected by uranium mining was found to be 91.3 nGy h−1, i.e., about two-fold higher than that in background area. The results of this preliminary study indicate the importance of radiological evaluation of the area and implementation of remedial measures in order to prevent further dispersion of radionuclides in the environment.",
journal = "Environmental Monitoring and Assessment",
title = "Distribution of natural radionuclides in surface soils in the vicinity of abandoned uranium mines in Serbia",
volume = "185",
number = "2",
pages = "1319-1329",
doi = "10.1007/s10661-012-2634-9"
}

Momčilović, M., Kovačević, J., Tanić, M., Đorđević, M., Bačić, G.,& Dragović, S. D.. (2013). Distribution of natural radionuclides in surface soils in the vicinity of abandoned uranium mines in Serbia. in Environmental Monitoring and Assessment, 185(2), 1319-1329.
https://doi.org/10.1007/s10661-012-2634-9

Momčilović M, Kovačević J, Tanić M, Đorđević M, Bačić G, Dragović SD. Distribution of natural radionuclides in surface soils in the vicinity of abandoned uranium mines in Serbia. in Environmental Monitoring and Assessment. 2013;185(2):1319-1329.
doi:10.1007/s10661-012-2634-9 .

Momčilović, Milan, Kovačević, Jovan, Tanić, Milan, Đorđević, Milan, Bačić, Goran, Dragović, Snežana D., "Distribution of natural radionuclides in surface soils in the vicinity of abandoned uranium mines in Serbia" in Environmental Monitoring and Assessment, 185, no. 2 (2013):1319-1329,
https://doi.org/10.1007/s10661-012-2634-9 . .

TY  - JOUR
AU  - Prokic, B. B.
AU  - Bačić, Goran
AU  - Prokic, B.
AU  - Kalijadis, Ana
AU  - Todorović, Vera
AU  - Puškaš, Nela
AU  - Vidojevic, D.
AU  - Laušević, Mila D.
AU  - Laušević, Zoran
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5251
AB  - In modern medicine implants are very important and so is their design and choice of materials. Almost equally important is the choice of imaging technique used to in vivo monitor their fate and biocompatibility. The aim of this study was to evaluate the ability of magnetic resonance imaging (MRI) in monitoring the biocompatibility of two newly designed carbon fibers. We have analyzed the interaction of surface functionalized carbon fibers (basic and acidic) with muscle and subcutaneous tissues of rabbits. MRI techniques showed to be useful in longitudinal monitoring of the surrounding tissues, assessment of biocompatibility of new implants, and in the distinction of in vivo surgical edema from inflammation. Histopathology confirmed MRI results, thus showing that MRI has a great potential for in vivo studies of such materials.
T2  - Acta Veterinaria, Beograd
T1  - In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues
VL  - 62
IS  - 5-6
SP  - 683
EP  - 696
DO  - 10.2298/AVB1206683P
ER  - 

@article{
author = "Prokic, B. B. and Bačić, Goran and Prokic, B. and Kalijadis, Ana and Todorović, Vera and Puškaš, Nela and Vidojevic, D. and Laušević, Mila D. and Laušević, Zoran",
year = "2012",
abstract = "In modern medicine implants are very important and so is their design and choice of materials. Almost equally important is the choice of imaging technique used to in vivo monitor their fate and biocompatibility. The aim of this study was to evaluate the ability of magnetic resonance imaging (MRI) in monitoring the biocompatibility of two newly designed carbon fibers. We have analyzed the interaction of surface functionalized carbon fibers (basic and acidic) with muscle and subcutaneous tissues of rabbits. MRI techniques showed to be useful in longitudinal monitoring of the surrounding tissues, assessment of biocompatibility of new implants, and in the distinction of in vivo surgical edema from inflammation. Histopathology confirmed MRI results, thus showing that MRI has a great potential for in vivo studies of such materials.",
journal = "Acta Veterinaria, Beograd",
title = "In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues",
volume = "62",
number = "5-6",
pages = "683-696",
doi = "10.2298/AVB1206683P"
}

Prokic, B. B., Bačić, G., Prokic, B., Kalijadis, A., Todorović, V., Puškaš, N., Vidojevic, D., Laušević, M. D.,& Laušević, Z.. (2012). In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues. in Acta Veterinaria, Beograd, 62(5-6), 683-696.
https://doi.org/10.2298/AVB1206683P

Prokic BB, Bačić G, Prokic B, Kalijadis A, Todorović V, Puškaš N, Vidojevic D, Laušević MD, Laušević Z. In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues. in Acta Veterinaria, Beograd. 2012;62(5-6):683-696.
doi:10.2298/AVB1206683P .

Prokic, B. B., Bačić, Goran, Prokic, B., Kalijadis, Ana, Todorović, Vera, Puškaš, Nela, Vidojevic, D., Laušević, Mila D., Laušević, Zoran, "In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues" in Acta Veterinaria, Beograd, 62, no. 5-6 (2012):683-696,
https://doi.org/10.2298/AVB1206683P . .