TY  - JOUR
AU  - Jovanović, Svetlana P.
AU  - Marković, Zoran M.
AU  - Kleut, Duška
AU  - Romčević, Nebojša Ž.
AU  - Trajković, Vladimir S.
AU  - Dramićanin, Miroslav
AU  - Todorović-Marković, Biljana
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3254
AB  - In this work we describe a novel method for highly efficient functionalization of single wall carbon nanotubes (SWCNTs) by DNA wrapping. Exposure of SWCNTs to gamma-irradiation (50 kGy) has lowered by one order of magnitude the amount of single stranded deoxyribonucleic acid (ssDNA) required for SWCNT modification. The resulting hybrids of gamma-irradiated SWCNTs and ssDNA were characterized by optical absorbance spectroscopy, Raman spectroscopy and Fourier transform infrared spectroscopy. Atomic force microscopy was used to investigate the morphology of hybrids. While gamma-irradiation in three different media has significantly improved the process of SWCNT dispersion, irradiation in ammonia was the most efficient. The gamma-irradiated SWCNTs functionalized with ssDNA were stabilized by electrostatic forces. This preliminary study suggests that gamma-irradiation can significantly improve the functionalization of SWCNTs with DNA.
T2  - Nanotechnology
T1  - A novel method for the functionalization of gamma-irradiated single wall carbon nanotubes with DNA
VL  - 20
IS  - 44
DO  - 10.1088/0957-4484/20/44/445602
ER  - 

@article{
author = "Jovanović, Svetlana P. and Marković, Zoran M. and Kleut, Duška and Romčević, Nebojša Ž. and Trajković, Vladimir S. and Dramićanin, Miroslav and Todorović-Marković, Biljana",
year = "2009",
abstract = "In this work we describe a novel method for highly efficient functionalization of single wall carbon nanotubes (SWCNTs) by DNA wrapping. Exposure of SWCNTs to gamma-irradiation (50 kGy) has lowered by one order of magnitude the amount of single stranded deoxyribonucleic acid (ssDNA) required for SWCNT modification. The resulting hybrids of gamma-irradiated SWCNTs and ssDNA were characterized by optical absorbance spectroscopy, Raman spectroscopy and Fourier transform infrared spectroscopy. Atomic force microscopy was used to investigate the morphology of hybrids. While gamma-irradiation in three different media has significantly improved the process of SWCNT dispersion, irradiation in ammonia was the most efficient. The gamma-irradiated SWCNTs functionalized with ssDNA were stabilized by electrostatic forces. This preliminary study suggests that gamma-irradiation can significantly improve the functionalization of SWCNTs with DNA.",
journal = "Nanotechnology",
title = "A novel method for the functionalization of gamma-irradiated single wall carbon nanotubes with DNA",
volume = "20",
number = "44",
doi = "10.1088/0957-4484/20/44/445602"
}

Jovanović, S. P., Marković, Z. M., Kleut, D., Romčević, N. Ž., Trajković, V. S., Dramićanin, M.,& Todorović-Marković, B.. (2009). A novel method for the functionalization of gamma-irradiated single wall carbon nanotubes with DNA. in Nanotechnology, 20(44).
https://doi.org/10.1088/0957-4484/20/44/445602

Jovanović SP, Marković ZM, Kleut D, Romčević NŽ, Trajković VS, Dramićanin M, Todorović-Marković B. A novel method for the functionalization of gamma-irradiated single wall carbon nanotubes with DNA. in Nanotechnology. 2009;20(44).
doi:10.1088/0957-4484/20/44/445602 .

Jovanović, Svetlana P., Marković, Zoran M., Kleut, Duška, Romčević, Nebojša Ž., Trajković, Vladimir S., Dramićanin, Miroslav, Todorović-Marković, Biljana, "A novel method for the functionalization of gamma-irradiated single wall carbon nanotubes with DNA" in Nanotechnology, 20, no. 44 (2009),
https://doi.org/10.1088/0957-4484/20/44/445602 . .

TY  - JOUR
AU  - Misirkić, Maja S.
AU  - Todorović-Marković, Biljana
AU  - Vucicevic, Ljubica M.
AU  - Janjetović, Kristina D.
AU  - Jokanović, Vukoman R.
AU  - Dramićanin, Miroslav
AU  - Marković, Zoran M.
AU  - Trajković, Vladimir S.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3659
AB  - The influence of fullerene (C-60) nanoparticles on the cytotoxicity of a highly reactive free radical nitric oxide (NO) was investigated. Fullerene nanoparticles were prepared by mechanochemically assisted complexation with anionic surfactant sodium dodecyl sulfate, macrocyclic oligosaccharide gamma-cyclodextrin or the copolymer ethylene vinyl acetate-ethylene vinyl versatate. C-60 nanoparticles were characterized by UV-vis and atomic force microscopy. While readily internalized by mouse L929 fibroblasts, C-60 nanoparticles were not cytotoxic. Moreover, they partially protected L929 cells from the cytotoxic effect of NO-releasing compounds sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP), S-nitrosoglutathione (GSNO) and 3-morpholino-sydnonimine (SIN-1). C-60 nanoparticles reduced SNP-induced apoptotic cell death by preventing mitochondrial depolarization, caspase activation, cell membrane phosphatidylserine exposure and DNA fragmentation. The protective action of C-60 nanoparticles was not exerted via direct interaction with NO, but through neutralization of mitochondria-produced superoxide radical in NO-treated cells, as demonstrated by using different redox-sensitive reporter fluorochromes. These data suggest that C-60 complexes with appropriate host molecules might be plausible candidates for preventing NO-mediated cell injury in inflammatory/autoimmune disorders. (C) 2009 Elsevier Ltd. All rights reserved.
T2  - Biomaterials
T1  - The protection of cells from nitric oxide-mediated apoptotic death by mechanochemically synthesized fullerene (C-60) nanoparticles
VL  - 30
IS  - 12
SP  - 2319
EP  - 2328
DO  - 10.1016/j.biomaterials.2009.01.023
ER  - 

@article{
author = "Misirkić, Maja S. and Todorović-Marković, Biljana and Vucicevic, Ljubica M. and Janjetović, Kristina D. and Jokanović, Vukoman R. and Dramićanin, Miroslav and Marković, Zoran M. and Trajković, Vladimir S.",
year = "2009",
abstract = "The influence of fullerene (C-60) nanoparticles on the cytotoxicity of a highly reactive free radical nitric oxide (NO) was investigated. Fullerene nanoparticles were prepared by mechanochemically assisted complexation with anionic surfactant sodium dodecyl sulfate, macrocyclic oligosaccharide gamma-cyclodextrin or the copolymer ethylene vinyl acetate-ethylene vinyl versatate. C-60 nanoparticles were characterized by UV-vis and atomic force microscopy. While readily internalized by mouse L929 fibroblasts, C-60 nanoparticles were not cytotoxic. Moreover, they partially protected L929 cells from the cytotoxic effect of NO-releasing compounds sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP), S-nitrosoglutathione (GSNO) and 3-morpholino-sydnonimine (SIN-1). C-60 nanoparticles reduced SNP-induced apoptotic cell death by preventing mitochondrial depolarization, caspase activation, cell membrane phosphatidylserine exposure and DNA fragmentation. The protective action of C-60 nanoparticles was not exerted via direct interaction with NO, but through neutralization of mitochondria-produced superoxide radical in NO-treated cells, as demonstrated by using different redox-sensitive reporter fluorochromes. These data suggest that C-60 complexes with appropriate host molecules might be plausible candidates for preventing NO-mediated cell injury in inflammatory/autoimmune disorders. (C) 2009 Elsevier Ltd. All rights reserved.",
journal = "Biomaterials",
title = "The protection of cells from nitric oxide-mediated apoptotic death by mechanochemically synthesized fullerene (C-60) nanoparticles",
volume = "30",
number = "12",
pages = "2319-2328",
doi = "10.1016/j.biomaterials.2009.01.023"
}

Misirkić, M. S., Todorović-Marković, B., Vucicevic, L. M., Janjetović, K. D., Jokanović, V. R., Dramićanin, M., Marković, Z. M.,& Trajković, V. S.. (2009). The protection of cells from nitric oxide-mediated apoptotic death by mechanochemically synthesized fullerene (C-60) nanoparticles. in Biomaterials, 30(12), 2319-2328.
https://doi.org/10.1016/j.biomaterials.2009.01.023

Misirkić MS, Todorović-Marković B, Vucicevic LM, Janjetović KD, Jokanović VR, Dramićanin M, Marković ZM, Trajković VS. The protection of cells from nitric oxide-mediated apoptotic death by mechanochemically synthesized fullerene (C-60) nanoparticles. in Biomaterials. 2009;30(12):2319-2328.
doi:10.1016/j.biomaterials.2009.01.023 .

Misirkić, Maja S., Todorović-Marković, Biljana, Vucicevic, Ljubica M., Janjetović, Kristina D., Jokanović, Vukoman R., Dramićanin, Miroslav, Marković, Zoran M., Trajković, Vladimir S., "The protection of cells from nitric oxide-mediated apoptotic death by mechanochemically synthesized fullerene (C-60) nanoparticles" in Biomaterials, 30, no. 12 (2009):2319-2328,
https://doi.org/10.1016/j.biomaterials.2009.01.023 . .