TY  - JOUR
AU  - Marković, Zoran M.
AU  - Jovanović, Svetlana P.
AU  - Mašković, Pavle Z.
AU  - Mojsin, Marija
AU  - Stevanović, Milena J.
AU  - Danko, Martin
AU  - Mičušik, Matej
AU  - Jovanović, Dragana J.
AU  - Kleinova, Angela
AU  - Špitalsky, Zdeno
AU  - Pavlović, Vladimir B.
AU  - Todorović-Marković, Biljana
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8591
AB  - Photoactive materials called photosensitizers can be used for treatment of different types of cancer in combination with light source. In this paper, we have investigated pro-oxidant and antioxidant potentials of four graphene based nanomaterials (graphene oxide-GO, graphene quantum dots-GQDs, carbon quantum dots-CQDs and N-doped carbon quantum dots-N-CQDs) depending on the presence/absence of visible light source. Structural and optical properties of these materials and their potentials for reactive oxygen species generation/quenching are investigated by applying different microscopy and spectroscopy techniques (transmission electron microscopy, FTIR, UV–Vis, photoluminescence, electron paramagnetic resonance). Results show that all types of quantum dots has pro-oxidant and antioxidant potentials whereas GO demonstrated only moderate antioxidant effect. The best free radical scavenger is CQDs sample in the absence of light. CQDs are the best singlet oxygen generator under blue light irradiation as well. To check photo-cytotoxicity of these materials, photo-cytotoxic concentrations of the GO, GQDs, CQDs and N-CQDs were determined for three cellular lines: human rhabdomyosarcoma (RD), cell line derived from human cervix carcinoma Hep2c (HeLa) and fibroblast cell line from murine (L2OB). Cytotoxicity test has indicated that all samples are much less photocytotoxic than cis-diamminedichloroplatinum (cis-DPP). The production method and doping of quantum dots affect the photodynamic activity of tested samples very much.
T2  - Journal of Photochemistry and Photobiology B: Biology
T1  - Graphene oxide size and structure pro-oxidant and antioxidant activity and photoinduced cytotoxicity relation on three cancer cell lines
VL  - 200
SP  - 111647
DO  - 10.1016/j.jphotobiol.2019.111647
ER  - 

@article{
author = "Marković, Zoran M. and Jovanović, Svetlana P. and Mašković, Pavle Z. and Mojsin, Marija and Stevanović, Milena J. and Danko, Martin and Mičušik, Matej and Jovanović, Dragana J. and Kleinova, Angela and Špitalsky, Zdeno and Pavlović, Vladimir B. and Todorović-Marković, Biljana",
year = "2019",
abstract = "Photoactive materials called photosensitizers can be used for treatment of different types of cancer in combination with light source. In this paper, we have investigated pro-oxidant and antioxidant potentials of four graphene based nanomaterials (graphene oxide-GO, graphene quantum dots-GQDs, carbon quantum dots-CQDs and N-doped carbon quantum dots-N-CQDs) depending on the presence/absence of visible light source. Structural and optical properties of these materials and their potentials for reactive oxygen species generation/quenching are investigated by applying different microscopy and spectroscopy techniques (transmission electron microscopy, FTIR, UV–Vis, photoluminescence, electron paramagnetic resonance). Results show that all types of quantum dots has pro-oxidant and antioxidant potentials whereas GO demonstrated only moderate antioxidant effect. The best free radical scavenger is CQDs sample in the absence of light. CQDs are the best singlet oxygen generator under blue light irradiation as well. To check photo-cytotoxicity of these materials, photo-cytotoxic concentrations of the GO, GQDs, CQDs and N-CQDs were determined for three cellular lines: human rhabdomyosarcoma (RD), cell line derived from human cervix carcinoma Hep2c (HeLa) and fibroblast cell line from murine (L2OB). Cytotoxicity test has indicated that all samples are much less photocytotoxic than cis-diamminedichloroplatinum (cis-DPP). The production method and doping of quantum dots affect the photodynamic activity of tested samples very much.",
journal = "Journal of Photochemistry and Photobiology B: Biology",
title = "Graphene oxide size and structure pro-oxidant and antioxidant activity and photoinduced cytotoxicity relation on three cancer cell lines",
volume = "200",
pages = "111647",
doi = "10.1016/j.jphotobiol.2019.111647"
}

Marković, Z. M., Jovanović, S. P., Mašković, P. Z., Mojsin, M., Stevanović, M. J., Danko, M., Mičušik, M., Jovanović, D. J., Kleinova, A., Špitalsky, Z., Pavlović, V. B.,& Todorović-Marković, B.. (2019). Graphene oxide size and structure pro-oxidant and antioxidant activity and photoinduced cytotoxicity relation on three cancer cell lines. in Journal of Photochemistry and Photobiology B: Biology, 200, 111647.
https://doi.org/10.1016/j.jphotobiol.2019.111647

Marković ZM, Jovanović SP, Mašković PZ, Mojsin M, Stevanović MJ, Danko M, Mičušik M, Jovanović DJ, Kleinova A, Špitalsky Z, Pavlović VB, Todorović-Marković B. Graphene oxide size and structure pro-oxidant and antioxidant activity and photoinduced cytotoxicity relation on three cancer cell lines. in Journal of Photochemistry and Photobiology B: Biology. 2019;200:111647.
doi:10.1016/j.jphotobiol.2019.111647 .

Marković, Zoran M., Jovanović, Svetlana P., Mašković, Pavle Z., Mojsin, Marija, Stevanović, Milena J., Danko, Martin, Mičušik, Matej, Jovanović, Dragana J., Kleinova, Angela, Špitalsky, Zdeno, Pavlović, Vladimir B., Todorović-Marković, Biljana, "Graphene oxide size and structure pro-oxidant and antioxidant activity and photoinduced cytotoxicity relation on three cancer cell lines" in Journal of Photochemistry and Photobiology B: Biology, 200 (2019):111647,
https://doi.org/10.1016/j.jphotobiol.2019.111647 . .

TY  - JOUR
AU  - Marković, Zoran M.
AU  - Kováčová, Mária
AU  - Mičušik, Matej
AU  - Danko, Martin
AU  - Švajdlenkova, Helena
AU  - Kleinova, Angela
AU  - Humpoliček, Petr
AU  - Lehocky, Marian
AU  - Todorović-Marković, Biljana
AU  - Špitalsky, Zdeno
PY  - 2019
UR  - http://doi.wiley.com/10.1002/app.47283
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8445
AB  - Various types of bacteria inhabit many surfaces thus causing problems which can have very strong impact on human health. Here we present a study of photophysical, mechanical, and antibacterial properties of curcumin/polyurethane nanocomposites prepared by swell-encapsulation-shrink method. The prepared nanocomposites have been characterized for degree of swelling, surface morphology, mechanical properties, chemical contents, photoluminescence, hydrophobicity, potentials for singlet oxygen generation, and antibacterial activity. Dynamic mechanical analysis has shown slight changes of glass temperature of curcumin/polyurethane nanocomposites due to blue light irradiation. It was found that nanocomposites have very strong photoluminescence, become photoactive upon blue light irradiation at 470 nm and generate singlet oxygen. Conducted antibacterial tests have shown very strong activity of these nanocomposites especially toward Escherichia coli. These bacteria strains have been eliminated completely only after 1 h irradiation by blue light. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 47283. © 2018 Wiley Periodicals, Inc.
T2  - Journal of Applied Polymer Science
T1  - Structural, mechanical, and antibacterial features of curcumin/polyurethane nanocomposites
VL  - 136
IS  - 13
SP  - 47283
DO  - 10.1002/app.47283
ER  - 

@article{
author = "Marković, Zoran M. and Kováčová, Mária and Mičušik, Matej and Danko, Martin and Švajdlenkova, Helena and Kleinova, Angela and Humpoliček, Petr and Lehocky, Marian and Todorović-Marković, Biljana and Špitalsky, Zdeno",
year = "2019",
abstract = "Various types of bacteria inhabit many surfaces thus causing problems which can have very strong impact on human health. Here we present a study of photophysical, mechanical, and antibacterial properties of curcumin/polyurethane nanocomposites prepared by swell-encapsulation-shrink method. The prepared nanocomposites have been characterized for degree of swelling, surface morphology, mechanical properties, chemical contents, photoluminescence, hydrophobicity, potentials for singlet oxygen generation, and antibacterial activity. Dynamic mechanical analysis has shown slight changes of glass temperature of curcumin/polyurethane nanocomposites due to blue light irradiation. It was found that nanocomposites have very strong photoluminescence, become photoactive upon blue light irradiation at 470 nm and generate singlet oxygen. Conducted antibacterial tests have shown very strong activity of these nanocomposites especially toward Escherichia coli. These bacteria strains have been eliminated completely only after 1 h irradiation by blue light. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 47283. © 2018 Wiley Periodicals, Inc.",
journal = "Journal of Applied Polymer Science",
title = "Structural, mechanical, and antibacterial features of curcumin/polyurethane nanocomposites",
volume = "136",
number = "13",
pages = "47283",
doi = "10.1002/app.47283"
}

Marković, Z. M., Kováčová, M., Mičušik, M., Danko, M., Švajdlenkova, H., Kleinova, A., Humpoliček, P., Lehocky, M., Todorović-Marković, B.,& Špitalsky, Z.. (2019). Structural, mechanical, and antibacterial features of curcumin/polyurethane nanocomposites. in Journal of Applied Polymer Science, 136(13), 47283.
https://doi.org/10.1002/app.47283

Marković ZM, Kováčová M, Mičušik M, Danko M, Švajdlenkova H, Kleinova A, Humpoliček P, Lehocky M, Todorović-Marković B, Špitalsky Z. Structural, mechanical, and antibacterial features of curcumin/polyurethane nanocomposites. in Journal of Applied Polymer Science. 2019;136(13):47283.
doi:10.1002/app.47283 .

Marković, Zoran M., Kováčová, Mária, Mičušik, Matej, Danko, Martin, Švajdlenkova, Helena, Kleinova, Angela, Humpoliček, Petr, Lehocky, Marian, Todorović-Marković, Biljana, Špitalsky, Zdeno, "Structural, mechanical, and antibacterial features of curcumin/polyurethane nanocomposites" in Journal of Applied Polymer Science, 136, no. 13 (2019):47283,
https://doi.org/10.1002/app.47283 . .