TY  - JOUR
AU  - Motorzhina, Anna
AU  - Jovanović, Sonja
AU  - Belyaev, Victor K.
AU  - Murzin, Dmitry
AU  - Pshenichnikov, Stanislav
AU  - Kolesnikova, Valeria G.
AU  - Omelyanchik, Alexander S.
AU  - Gazvoda, Lea
AU  - Spreitzer, Matjaž
AU  - Panina, Larissa
AU  - Rodionova, Valeria
AU  - Vukomanović, Marija
AU  - Levada, Kateryna
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10099
AB  - The combination of plasmonic material and magnetic metal oxide nanoparticles is widely used in multifunctional nanosystems. Here we propose a method for the fabrication of a gold/cobalt ferrite nanocomposite for biomedical applications. The composite includes gold cores of ~10 nm in diameter coated with arginine, which are surrounded by small cobalt ferrite nanoparticles with diameters of ~5 nm covered with dihydrocaffeic acid. The structure and elemental composition, morphology and dimensions, magnetic and optical properties, and biocompatibility of new nanocomposite were studied. The magnetic properties of the composite are mostly determined by the superparamagnetic state of cobalt ferrite nanoparticles, and optical properties are influenced by the localized plasmon resonance in gold nanoparticles. The cytotoxicity of gold/cobalt ferrite nanocomposite was tested using T-lymphoblastic leukemia and peripheral blood mononuclear cells. Studied composite has selective citotoxic effect on cancerous cells while it has no cytotoxic effect on healtly cells. The results suggest that this material can be explored in the future for combined photothermal treatment and magnetic theranostic.
T2  - Processes
T1  - Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties
VL  - 9
IS  - 12
SP  - 2264
DO  - 10.3390/pr9122264
ER  - 

@article{
author = "Motorzhina, Anna and Jovanović, Sonja and Belyaev, Victor K. and Murzin, Dmitry and Pshenichnikov, Stanislav and Kolesnikova, Valeria G. and Omelyanchik, Alexander S. and Gazvoda, Lea and Spreitzer, Matjaž and Panina, Larissa and Rodionova, Valeria and Vukomanović, Marija and Levada, Kateryna",
year = "2021",
abstract = "The combination of plasmonic material and magnetic metal oxide nanoparticles is widely used in multifunctional nanosystems. Here we propose a method for the fabrication of a gold/cobalt ferrite nanocomposite for biomedical applications. The composite includes gold cores of ~10 nm in diameter coated with arginine, which are surrounded by small cobalt ferrite nanoparticles with diameters of ~5 nm covered with dihydrocaffeic acid. The structure and elemental composition, morphology and dimensions, magnetic and optical properties, and biocompatibility of new nanocomposite were studied. The magnetic properties of the composite are mostly determined by the superparamagnetic state of cobalt ferrite nanoparticles, and optical properties are influenced by the localized plasmon resonance in gold nanoparticles. The cytotoxicity of gold/cobalt ferrite nanocomposite was tested using T-lymphoblastic leukemia and peripheral blood mononuclear cells. Studied composite has selective citotoxic effect on cancerous cells while it has no cytotoxic effect on healtly cells. The results suggest that this material can be explored in the future for combined photothermal treatment and magnetic theranostic.",
journal = "Processes",
title = "Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties",
volume = "9",
number = "12",
pages = "2264",
doi = "10.3390/pr9122264"
}

Motorzhina, A., Jovanović, S., Belyaev, V. K., Murzin, D., Pshenichnikov, S., Kolesnikova, V. G., Omelyanchik, A. S., Gazvoda, L., Spreitzer, M., Panina, L., Rodionova, V., Vukomanović, M.,& Levada, K.. (2021). Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties. in Processes, 9(12), 2264.
https://doi.org/10.3390/pr9122264

Motorzhina A, Jovanović S, Belyaev VK, Murzin D, Pshenichnikov S, Kolesnikova VG, Omelyanchik AS, Gazvoda L, Spreitzer M, Panina L, Rodionova V, Vukomanović M, Levada K. Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties. in Processes. 2021;9(12):2264.
doi:10.3390/pr9122264 .

Motorzhina, Anna, Jovanović, Sonja, Belyaev, Victor K., Murzin, Dmitry, Pshenichnikov, Stanislav, Kolesnikova, Valeria G., Omelyanchik, Alexander S., Gazvoda, Lea, Spreitzer, Matjaž, Panina, Larissa, Rodionova, Valeria, Vukomanović, Marija, Levada, Kateryna, "Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties" in Processes, 9, no. 12 (2021):2264,
https://doi.org/10.3390/pr9122264 . .