Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200017 (University of Belgrade, Institute of Nuclear Sciences 'Vinča', Belgrade-Vinča)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200017 (University of Belgrade, Institute of Nuclear Sciences 'Vinča', Belgrade-Vinča) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200017 (Univerzitet u Beogradu, Institut za nuklearne nauke Vinča, Beograd-Vinča) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200017 (Универзитет у Београду, Институт за нуклеарне науке Винча, Београд-Винча) (sr)
Authors

Publications

Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle

Đurić, Tamara; Kuveljić, Jovana; Đorđević, Ana; Dekleva, Milica; Stanković, Goran; Stanković, Aleksandra; Živković, Maja

TY  - JOUR
AU  - Đurić, Tamara
AU  - Kuveljić, Jovana
AU  - Đorđević, Ana
AU  - Dekleva, Milica
AU  - Stanković, Goran
AU  - Stanković, Aleksandra
AU  - Živković, Maja
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10382
AB  - Background Myocardial infarction (MI) leads to ischemia and afterward to left ventricular (LV) remodeling. Matrix metalloproteinase−1 (MMP1) and −3 (MMP3) belong to the family of endopeptidases and together they can dissolve most of the components of the extracellular matrix. MMP1 and MMP3 variants have been investigated solely in association with ischemic heart disease and LV dysfunction, but not in haplotype. The aims of this study were to investigate the association of haplotypes inferred from MMP1 rs1799750 (−1607 1G/2G; NC_000011.9:g.102670497del) and MMP3 rs35068180 (−1612 5A/6A; NC_000011.9:g.102715952dup) with MI and their effect on the change in echocardiographic parameters of LV structure and function in patients within 6 months after MI. Methods The study included 325 patients with the first MI and 283 healthy controls. Gene variants were detected by PCR-RFLP method. Parameters of LV structure and function were assessed by conventional 2D echocardiography, 3–5 days and 6 months after the first MI, on a subgroup of 160 patients. Haplotype analysis was performed with Thesias software. Results Haplotypes 2G-5A and 1G-6A were significantly and independently associated with MI compared with the reference haplotype 2G-6A (adjusted, p = 0.009 and p = 0.026, respectively). After Bonferroni correction for multiple testing, MMP1 and MMP3 haplotypes lost their association with the change in LV long diameter and stroke volume within 6 months after MI. Conclusion MMP1 and MMP3 haplotypes are strongly associated with MI. Further studies are needed to validate this result and to examine their association with echocardiographic parameters of LV structure and function after MI.
T2  - Molecular Genetics & Genomic Medicine
T1  - Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle
SP  - e2022
DO  - 10.1002/mgg3.2022
ER  - 
@article{
author = "Đurić, Tamara and Kuveljić, Jovana and Đorđević, Ana and Dekleva, Milica and Stanković, Goran and Stanković, Aleksandra and Živković, Maja",
abstract = "Background Myocardial infarction (MI) leads to ischemia and afterward to left ventricular (LV) remodeling. Matrix metalloproteinase−1 (MMP1) and −3 (MMP3) belong to the family of endopeptidases and together they can dissolve most of the components of the extracellular matrix. MMP1 and MMP3 variants have been investigated solely in association with ischemic heart disease and LV dysfunction, but not in haplotype. The aims of this study were to investigate the association of haplotypes inferred from MMP1 rs1799750 (−1607 1G/2G; NC_000011.9:g.102670497del) and MMP3 rs35068180 (−1612 5A/6A; NC_000011.9:g.102715952dup) with MI and their effect on the change in echocardiographic parameters of LV structure and function in patients within 6 months after MI. Methods The study included 325 patients with the first MI and 283 healthy controls. Gene variants were detected by PCR-RFLP method. Parameters of LV structure and function were assessed by conventional 2D echocardiography, 3–5 days and 6 months after the first MI, on a subgroup of 160 patients. Haplotype analysis was performed with Thesias software. Results Haplotypes 2G-5A and 1G-6A were significantly and independently associated with MI compared with the reference haplotype 2G-6A (adjusted, p = 0.009 and p = 0.026, respectively). After Bonferroni correction for multiple testing, MMP1 and MMP3 haplotypes lost their association with the change in LV long diameter and stroke volume within 6 months after MI. Conclusion MMP1 and MMP3 haplotypes are strongly associated with MI. Further studies are needed to validate this result and to examine their association with echocardiographic parameters of LV structure and function after MI.",
journal = "Molecular Genetics & Genomic Medicine",
title = "Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle",
pages = "e2022",
doi = "10.1002/mgg3.2022"
}
Đurić, T., Kuveljić, J., Đorđević, A., Dekleva, M., Stanković, G., Stanković, A.,& Živković, M..Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle. in Molecular Genetics & Genomic Medicine, e2022.
https://doi.org/10.1002/mgg3.2022
Đurić T, Kuveljić J, Đorđević A, Dekleva M, Stanković G, Stanković A, Živković M. Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle. in Molecular Genetics & Genomic Medicine.:e2022.
doi:10.1002/mgg3.2022 .
Đurić, Tamara, Kuveljić, Jovana, Đorđević, Ana, Dekleva, Milica, Stanković, Goran, Stanković, Aleksandra, Živković, Maja, "Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle" in Molecular Genetics & Genomic Medicine:e2022,
https://doi.org/10.1002/mgg3.2022 . .

Non-coding RNA and cholesteatoma

Jovanović, Ivan G.; Živković, Maja; Ješić, Snežana; Stanković, Aleksandra

TY  - JOUR
AU  - Jovanović, Ivan G.
AU  - Živković, Maja
AU  - Ješić, Snežana
AU  - Stanković, Aleksandra
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10115
AB  - Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master regulators orchestrating disease progression are still unknown. Therefore, in this review, we will discuss the diagnostic and therapeutic potential of non-coding RNAs (ncRNA) as a new class of regulatory molecules. Methods We have comprehensively reviewed all articles investigating ncRNAs, specifically micro RNAs (miRNAs) and long ncRNAs (lncRNA/circRNA) in cholesteatoma tissue. Results Candidate miRNA approaches indicated that miR-21 and let-7a are the major miRNAs involved in cholesteatoma growth, migration, proliferation, bone destruction, and apoptosis. Regulatory potential for the same biological processes was also observed for miR-203a. The NF-kB/miR-802/PTEN regulatory network was in relation to observed miR-21 activity in cholesteatoma as well. High throughput approaches revealed additional ncRNAs implicated in cholesteatoma pathology. Competitive endogenous RNA (ceRNA) analysis highlighted lncRNA/circRNA that could be “endogenous sponge” for miR-21 and let-7a based on the hypothesis that RNA transcripts can communicate with and regulate each other by using shared miRNA response elements. Conclusion In this review, we summarize the discoveries and role of ncRNA in major pathways in cholesteatoma and highlight the potential of miRNA-based therapeutics in the treatment of cholesteatoma. Level of Evidence: NA.
T2  - Laryngoscope Investigative Otolaryngology
T2  - Laryngoscope Investigative Otolaryngology
T1  - Non-coding RNA and cholesteatoma
DO  - 10.1002/lio2.728
ER  - 
@article{
author = "Jovanović, Ivan G. and Živković, Maja and Ješić, Snežana and Stanković, Aleksandra",
abstract = "Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master regulators orchestrating disease progression are still unknown. Therefore, in this review, we will discuss the diagnostic and therapeutic potential of non-coding RNAs (ncRNA) as a new class of regulatory molecules. Methods We have comprehensively reviewed all articles investigating ncRNAs, specifically micro RNAs (miRNAs) and long ncRNAs (lncRNA/circRNA) in cholesteatoma tissue. Results Candidate miRNA approaches indicated that miR-21 and let-7a are the major miRNAs involved in cholesteatoma growth, migration, proliferation, bone destruction, and apoptosis. Regulatory potential for the same biological processes was also observed for miR-203a. The NF-kB/miR-802/PTEN regulatory network was in relation to observed miR-21 activity in cholesteatoma as well. High throughput approaches revealed additional ncRNAs implicated in cholesteatoma pathology. Competitive endogenous RNA (ceRNA) analysis highlighted lncRNA/circRNA that could be “endogenous sponge” for miR-21 and let-7a based on the hypothesis that RNA transcripts can communicate with and regulate each other by using shared miRNA response elements. Conclusion In this review, we summarize the discoveries and role of ncRNA in major pathways in cholesteatoma and highlight the potential of miRNA-based therapeutics in the treatment of cholesteatoma. Level of Evidence: NA.",
journal = "Laryngoscope Investigative Otolaryngology, Laryngoscope Investigative Otolaryngology",
title = "Non-coding RNA and cholesteatoma",
doi = "10.1002/lio2.728"
}
Jovanović, I. G., Živković, M., Ješić, S.,& Stanković, A..Non-coding RNA and cholesteatoma. in Laryngoscope Investigative Otolaryngology.
https://doi.org/10.1002/lio2.728
Jovanović IG, Živković M, Ješić S, Stanković A. Non-coding RNA and cholesteatoma. in Laryngoscope Investigative Otolaryngology..
doi:10.1002/lio2.728 .
Jovanović, Ivan G., Živković, Maja, Ješić, Snežana, Stanković, Aleksandra, "Non-coding RNA and cholesteatoma" in Laryngoscope Investigative Otolaryngology,
https://doi.org/10.1002/lio2.728 . .
1

Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer

Stojković, Goran; Jovanović, Ivan G.; Dimitrijević, Milovan; Jovanović, Jasmina; Tomanović, Nada; Stanković, Aleksandra; Arsović, Nenad; Boričić, Ivan; Zeljić, Katarina

TY  - JOUR
AU  - Stojković, Goran
AU  - Jovanović, Ivan G.
AU  - Dimitrijević, Milovan
AU  - Jovanović, Jasmina
AU  - Tomanović, Nada
AU  - Stanković, Aleksandra
AU  - Arsović, Nenad
AU  - Boričić, Ivan
AU  - Zeljić, Katarina
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10217
AB  - Objectives This study aimed to experimentally validate dysregulated expression of miRNA candidates selected through updated meta-analysis of most commonly deregulated miRNAs in oral cancer and to explore their diagnostic and prognostic potential. Materials and methods Five miRNAs (miR-31-3p, miR-135b-5p, miR-18a-5p, miR-30a-5p and miR-139-5p) from updated meta-signature were selected for validation by qRT-PCR method in 35 oral cancer clinical specimens and adjacent non-cancerous tissue. Results Updated meta-analysis has identified 13 most commonly deregulated miRNAs in oral cancer. Seven miRNAs were consistently up-regulated (miR-21-5p, miR-31-3p, miR-135b-5p, miR-31-5p, miR-424-5p, miR-18a-5p and miR-21-3p), while five were down-regulated (miR-139-5p, miR-30a-3p, miR-375-3p, miR-376c-3p and miR-30a-5p). Increased expression of miR-31-3p and miR-135b-5p, and decreased expression of miR-139-5p and miR-30a-5p were confirmed in oral cancer compared to adjacent non-cancerous tissue. A three miRNAs combination (miR-31-3p, miR-139-5p and miR-30a-5p) gave the most promising diagnostic potential for discriminating oral cancer from non-cancerous tissue (AUC: 0.780 [95% CI: 0.673–0.886], p < 0.0005, sensitivity 94.3%, specificity 51.4%). High expression of miR-135b-5p, miR-18a-5p and miR-30a-5p was associated with poor survival (p = 0.003, p = 0.048, p = 0.016 respectively). Conclusion miR-31-3p, miR-139-5p and miR-30a-5p panel was confirmed as a potential diagnostic biomarker when distinguishing oral cancer from non-cancerous tissue. miR-135b-5p, miR-18a-5p and miR-30a-5p might serve as potential biomarkers of poor survival of oral cancer patients.
T2  - Oral Diseases
T1  - Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer
DO  - 10.1111/odi.14185
ER  - 
@article{
author = "Stojković, Goran and Jovanović, Ivan G. and Dimitrijević, Milovan and Jovanović, Jasmina and Tomanović, Nada and Stanković, Aleksandra and Arsović, Nenad and Boričić, Ivan and Zeljić, Katarina",
abstract = "Objectives This study aimed to experimentally validate dysregulated expression of miRNA candidates selected through updated meta-analysis of most commonly deregulated miRNAs in oral cancer and to explore their diagnostic and prognostic potential. Materials and methods Five miRNAs (miR-31-3p, miR-135b-5p, miR-18a-5p, miR-30a-5p and miR-139-5p) from updated meta-signature were selected for validation by qRT-PCR method in 35 oral cancer clinical specimens and adjacent non-cancerous tissue. Results Updated meta-analysis has identified 13 most commonly deregulated miRNAs in oral cancer. Seven miRNAs were consistently up-regulated (miR-21-5p, miR-31-3p, miR-135b-5p, miR-31-5p, miR-424-5p, miR-18a-5p and miR-21-3p), while five were down-regulated (miR-139-5p, miR-30a-3p, miR-375-3p, miR-376c-3p and miR-30a-5p). Increased expression of miR-31-3p and miR-135b-5p, and decreased expression of miR-139-5p and miR-30a-5p were confirmed in oral cancer compared to adjacent non-cancerous tissue. A three miRNAs combination (miR-31-3p, miR-139-5p and miR-30a-5p) gave the most promising diagnostic potential for discriminating oral cancer from non-cancerous tissue (AUC: 0.780 [95% CI: 0.673–0.886], p < 0.0005, sensitivity 94.3%, specificity 51.4%). High expression of miR-135b-5p, miR-18a-5p and miR-30a-5p was associated with poor survival (p = 0.003, p = 0.048, p = 0.016 respectively). Conclusion miR-31-3p, miR-139-5p and miR-30a-5p panel was confirmed as a potential diagnostic biomarker when distinguishing oral cancer from non-cancerous tissue. miR-135b-5p, miR-18a-5p and miR-30a-5p might serve as potential biomarkers of poor survival of oral cancer patients.",
journal = "Oral Diseases",
title = "Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer",
doi = "10.1111/odi.14185"
}
Stojković, G., Jovanović, I. G., Dimitrijević, M., Jovanović, J., Tomanović, N., Stanković, A., Arsović, N., Boričić, I.,& Zeljić, K..Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer. in Oral Diseases.
https://doi.org/10.1111/odi.14185
Stojković G, Jovanović IG, Dimitrijević M, Jovanović J, Tomanović N, Stanković A, Arsović N, Boričić I, Zeljić K. Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer. in Oral Diseases..
doi:10.1111/odi.14185 .
Stojković, Goran, Jovanović, Ivan G., Dimitrijević, Milovan, Jovanović, Jasmina, Tomanović, Nada, Stanković, Aleksandra, Arsović, Nenad, Boričić, Ivan, Zeljić, Katarina, "Meta-signature guided investigation of miRNA candidates as potential biomarkers of oral cancer" in Oral Diseases,
https://doi.org/10.1111/odi.14185 . .

Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex

Martinović, Jelena; Zarić Kontić, Marina; Dragić, Milorad; Todorović, Ana; Guševac Stojanović, Ivana; Mitrović, Nataša; Grković, Ivana; Drakulić, Dunja

(2023)

TY  - JOUR
AU  - Martinović, Jelena
AU  - Zarić Kontić, Marina
AU  - Dragić, Milorad
AU  - Todorović, Ana
AU  - Guševac Stojanović, Ivana
AU  - Mitrović, Nataša
AU  - Grković, Ivana
AU  - Drakulić, Dunja
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10461
AB  - D-galactose (d-gal) is broadly used in animal aging studies as its chronic administration mimics learning and memory impairments related to aging in humans. However, within the few studies that utilize chronic oral d-gal intake, none of them is focused on alteration in synaptic structure and function. We examined the effects of 6-weeks oral d-gal intake (200 mg/kg and 500 mg/kg, dissolved in tap water) on age-related changes, with emphasis on the prefrontal cortex (PFC) and hippocampus (HIP) of adult male Wistar rats. Memory assessment was followed by histological examination of the PFC and HIP (Nissl staining and Iba-1 immunostaining), while in crude synaptosomal fractions the state of oxidative stress and the expression of proteins involved in glutamatergic signaling was determined. Although applied dosages compromised memory, alterations such as impaired sensory-motor function and aberrant morphology were not detected. In the PFC, analysis of microglia revealed reduction of branching pattern following d-gal intake, in parallel with increased oxidative damage of proteins, lipids and disturbed pro-oxidant antioxidant balance. These changes in the PFC were further accompanied with decreased levels of vesicular glutamate transporter 1, syntaxin-1 and NMDA receptor 2B subunit in both treated groups. Simultaneously, the increased hippocampal oxidative damage of lipids was detected. Results indicate successful provocation of age-related changes following oral d-gal intake, and suggest greater sensitivity of the PFC to d-gal treatment than HIP.
T2  - Behavioural Brain Research
T1  - Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex
VL  - 436
SP  - 114072
DO  - 10.1016/j.bbr.2022.114072
ER  - 
@article{
author = "Martinović, Jelena and Zarić Kontić, Marina and Dragić, Milorad and Todorović, Ana and Guševac Stojanović, Ivana and Mitrović, Nataša and Grković, Ivana and Drakulić, Dunja",
year = "2023",
abstract = "D-galactose (d-gal) is broadly used in animal aging studies as its chronic administration mimics learning and memory impairments related to aging in humans. However, within the few studies that utilize chronic oral d-gal intake, none of them is focused on alteration in synaptic structure and function. We examined the effects of 6-weeks oral d-gal intake (200 mg/kg and 500 mg/kg, dissolved in tap water) on age-related changes, with emphasis on the prefrontal cortex (PFC) and hippocampus (HIP) of adult male Wistar rats. Memory assessment was followed by histological examination of the PFC and HIP (Nissl staining and Iba-1 immunostaining), while in crude synaptosomal fractions the state of oxidative stress and the expression of proteins involved in glutamatergic signaling was determined. Although applied dosages compromised memory, alterations such as impaired sensory-motor function and aberrant morphology were not detected. In the PFC, analysis of microglia revealed reduction of branching pattern following d-gal intake, in parallel with increased oxidative damage of proteins, lipids and disturbed pro-oxidant antioxidant balance. These changes in the PFC were further accompanied with decreased levels of vesicular glutamate transporter 1, syntaxin-1 and NMDA receptor 2B subunit in both treated groups. Simultaneously, the increased hippocampal oxidative damage of lipids was detected. Results indicate successful provocation of age-related changes following oral d-gal intake, and suggest greater sensitivity of the PFC to d-gal treatment than HIP.",
journal = "Behavioural Brain Research",
title = "Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex",
volume = "436",
pages = "114072",
doi = "10.1016/j.bbr.2022.114072"
}
Martinović, J., Zarić Kontić, M., Dragić, M., Todorović, A., Guševac Stojanović, I., Mitrović, N., Grković, I.,& Drakulić, D.. (2023). Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex. in Behavioural Brain Research, 436, 114072.
https://doi.org/10.1016/j.bbr.2022.114072
Martinović J, Zarić Kontić M, Dragić M, Todorović A, Guševac Stojanović I, Mitrović N, Grković I, Drakulić D. Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex. in Behavioural Brain Research. 2023;436:114072.
doi:10.1016/j.bbr.2022.114072 .
Martinović, Jelena, Zarić Kontić, Marina, Dragić, Milorad, Todorović, Ana, Guševac Stojanović, Ivana, Mitrović, Nataša, Grković, Ivana, Drakulić, Dunja, "Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex" in Behavioural Brain Research, 436 (2023):114072,
https://doi.org/10.1016/j.bbr.2022.114072 . .

Influence of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) polymer matrix composition on the bonding environment and characteristics of Ag nanoparticles produced by gamma irradiation

Nikolić, Nikolina; Spasojević, Jelena P.; Radosavljević, Aleksandra; Milošević, Milica V.; Barudžija, Tanja; Rakočević, Lazar; Kačarević-Popović, Zorica M.

(2023)

TY  - JOUR
AU  - Nikolić, Nikolina
AU  - Spasojević, Jelena P.
AU  - Radosavljević, Aleksandra
AU  - Milošević, Milica V.
AU  - Barudžija, Tanja
AU  - Rakočević, Lazar
AU  - Kačarević-Popović, Zorica M.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10449
AB  - A series of silver nanoparticles (AgNPs)-poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) (PVA/PVP) hydrogel nanocomposites were synthesized by gamma irradiation to examine the matrix's impact on properties of Ag nanocrystals important for strain engineering in functional materials. SEM analysis and the swelling studies revealed nanocomposite morphology and fluid transport properties. UV–Vis absorption characterization of AgNPs has enabled an understanding of the cluster size effects. The gel content indicated inter-crosslinking of the two components of the polymer matrix, especially for equivalent (1:1) PVA/PVP ratio, affecting the investigated AgNPs structural parameters. The lattice parameters and the interface stress, analyzed using XRD, have the lowest negative magnitude from the bulk lattice constant for the PVA/PVP (2:1) and (1:1) ratio. The lowest values of the lattice strain and dislocation density, as mutually dependent parameters, are obtained in AgNPs embedded in a PVA/PVP (2:1) and (1:1) matrix. The XPS and FTIR data show a positive shift of the O1s and a redshift of the CO – Ag vibration band indicating charge transfer to the vacant orbital of Ag nanocrystals. The N atoms of the pyrrolidine ring are not directly involved in the electronic interactions, but over the p-π conjugation with carbonyl O. In addition, the tested Ag-(PVA/PVP) hydrogel nanocomposites showed significant potential as a broad-spectrum antibacterial material.
T2  - Radiation Physics and Chemistry
T1  - Influence of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) polymer matrix composition on the bonding environment and characteristics of Ag nanoparticles produced by gamma irradiation
VL  - 202
SP  - 110564
DO  - 10.1016/j.radphyschem.2022.110564
ER  - 
@article{
author = "Nikolić, Nikolina and Spasojević, Jelena P. and Radosavljević, Aleksandra and Milošević, Milica V. and Barudžija, Tanja and Rakočević, Lazar and Kačarević-Popović, Zorica M.",
year = "2023",
abstract = "A series of silver nanoparticles (AgNPs)-poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) (PVA/PVP) hydrogel nanocomposites were synthesized by gamma irradiation to examine the matrix's impact on properties of Ag nanocrystals important for strain engineering in functional materials. SEM analysis and the swelling studies revealed nanocomposite morphology and fluid transport properties. UV–Vis absorption characterization of AgNPs has enabled an understanding of the cluster size effects. The gel content indicated inter-crosslinking of the two components of the polymer matrix, especially for equivalent (1:1) PVA/PVP ratio, affecting the investigated AgNPs structural parameters. The lattice parameters and the interface stress, analyzed using XRD, have the lowest negative magnitude from the bulk lattice constant for the PVA/PVP (2:1) and (1:1) ratio. The lowest values of the lattice strain and dislocation density, as mutually dependent parameters, are obtained in AgNPs embedded in a PVA/PVP (2:1) and (1:1) matrix. The XPS and FTIR data show a positive shift of the O1s and a redshift of the CO – Ag vibration band indicating charge transfer to the vacant orbital of Ag nanocrystals. The N atoms of the pyrrolidine ring are not directly involved in the electronic interactions, but over the p-π conjugation with carbonyl O. In addition, the tested Ag-(PVA/PVP) hydrogel nanocomposites showed significant potential as a broad-spectrum antibacterial material.",
journal = "Radiation Physics and Chemistry",
title = "Influence of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) polymer matrix composition on the bonding environment and characteristics of Ag nanoparticles produced by gamma irradiation",
volume = "202",
pages = "110564",
doi = "10.1016/j.radphyschem.2022.110564"
}
Nikolić, N., Spasojević, J. P., Radosavljević, A., Milošević, M. V., Barudžija, T., Rakočević, L.,& Kačarević-Popović, Z. M.. (2023). Influence of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) polymer matrix composition on the bonding environment and characteristics of Ag nanoparticles produced by gamma irradiation. in Radiation Physics and Chemistry, 202, 110564.
https://doi.org/10.1016/j.radphyschem.2022.110564
Nikolić N, Spasojević JP, Radosavljević A, Milošević MV, Barudžija T, Rakočević L, Kačarević-Popović ZM. Influence of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) polymer matrix composition on the bonding environment and characteristics of Ag nanoparticles produced by gamma irradiation. in Radiation Physics and Chemistry. 2023;202:110564.
doi:10.1016/j.radphyschem.2022.110564 .
Nikolić, Nikolina, Spasojević, Jelena P., Radosavljević, Aleksandra, Milošević, Milica V., Barudžija, Tanja, Rakočević, Lazar, Kačarević-Popović, Zorica M., "Influence of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) polymer matrix composition on the bonding environment and characteristics of Ag nanoparticles produced by gamma irradiation" in Radiation Physics and Chemistry, 202 (2023):110564,
https://doi.org/10.1016/j.radphyschem.2022.110564 . .

Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers

Ahmetović, Sanita; Vasiljević, Zorka Ž.; Rajić, Vladimir; Bartolić, Dragana; Novaković, Mirjana; Tadić, Nenad B.; Cvjetićanin, Nikola; Nikolić, Maria Vesna

(2023)

TY  - JOUR
AU  - Ahmetović, Sanita
AU  - Vasiljević, Zorka Ž.
AU  - Rajić, Vladimir
AU  - Bartolić, Dragana
AU  - Novaković, Mirjana
AU  - Tadić, Nenad B.
AU  - Cvjetićanin, Nikola
AU  - Nikolić, Maria Vesna
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10448
AB  - Pure and samarium (Sm3+) - or zirconium (Zr4+)-doped TiO2 nanofibers were synthesized by electrospinning method followed by calcination at 500 °C for 1 h. As-spun fibers were smooth, straight and continuous, whilst EDS analysis confirmed the fiber composition and incorporation of dopants in the fibers. Doping with Sm3+ and Zr4+ greatly inhibited the phase transformation of anatase to rutile, by surrounding of Sm3+ ions through formation of Ti-O-Sm bonds and by replacement of Ti4+ ions with larger Zr4+ ions. This was confirmed by HRTEM and SAED analysis. The size of nanofibers was determined to be 133 nm, 175 nm and 155 nm for pure, (0.5%)Sm3+:TiO2 and (1%)Zr4+:TiO2, respectively. After calcination, TiO2 crystal lattice with interplanar spacing of 0.353 nm of (101) crystal plane was not significantly disturbed by Sm doping whilst crystal lattice spacing of 0.357 nm of (101) planes of anatase phase in case TiO2:1.0%Zr4+, significantly differs from the value of pure TiO2 (0.352 nm), thus implying that Zr was doped into substitutional sites of the TiO2 lattice. The indirect band gaps were calculated to be in the range 3.07–3.24 eV. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ exhibited higher specific surface area, of 47.1 and 59.4 m2/g, respectively, than pure TiO2 fibers (19.7 m2/g). Effects of Sm3+ and Zr4+ dopant content on the photodegradation efficiency of methylene blue (MB) were studied. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ nanofibers have shown the highest photocatalytic activity of 97% and 98% with constant rates 0.01768 min−1 and 0.01939 min−1, respectively, within180 min irradiation under visible light.
T2  - Journal of Alloys and Compounds
T1  - Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers
VL  - 930
SP  - 167423
DO  - 10.1016/j.jallcom.2022.167423
ER  - 
@article{
author = "Ahmetović, Sanita and Vasiljević, Zorka Ž. and Rajić, Vladimir and Bartolić, Dragana and Novaković, Mirjana and Tadić, Nenad B. and Cvjetićanin, Nikola and Nikolić, Maria Vesna",
year = "2023",
abstract = "Pure and samarium (Sm3+) - or zirconium (Zr4+)-doped TiO2 nanofibers were synthesized by electrospinning method followed by calcination at 500 °C for 1 h. As-spun fibers were smooth, straight and continuous, whilst EDS analysis confirmed the fiber composition and incorporation of dopants in the fibers. Doping with Sm3+ and Zr4+ greatly inhibited the phase transformation of anatase to rutile, by surrounding of Sm3+ ions through formation of Ti-O-Sm bonds and by replacement of Ti4+ ions with larger Zr4+ ions. This was confirmed by HRTEM and SAED analysis. The size of nanofibers was determined to be 133 nm, 175 nm and 155 nm for pure, (0.5%)Sm3+:TiO2 and (1%)Zr4+:TiO2, respectively. After calcination, TiO2 crystal lattice with interplanar spacing of 0.353 nm of (101) crystal plane was not significantly disturbed by Sm doping whilst crystal lattice spacing of 0.357 nm of (101) planes of anatase phase in case TiO2:1.0%Zr4+, significantly differs from the value of pure TiO2 (0.352 nm), thus implying that Zr was doped into substitutional sites of the TiO2 lattice. The indirect band gaps were calculated to be in the range 3.07–3.24 eV. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ exhibited higher specific surface area, of 47.1 and 59.4 m2/g, respectively, than pure TiO2 fibers (19.7 m2/g). Effects of Sm3+ and Zr4+ dopant content on the photodegradation efficiency of methylene blue (MB) were studied. TiO2:0.5%Sm3+ and TiO2:1.0%Zr4+ nanofibers have shown the highest photocatalytic activity of 97% and 98% with constant rates 0.01768 min−1 and 0.01939 min−1, respectively, within180 min irradiation under visible light.",
journal = "Journal of Alloys and Compounds",
title = "Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers",
volume = "930",
pages = "167423",
doi = "10.1016/j.jallcom.2022.167423"
}
Ahmetović, S., Vasiljević, Z. Ž., Rajić, V., Bartolić, D., Novaković, M., Tadić, N. B., Cvjetićanin, N.,& Nikolić, M. V.. (2023). Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers. in Journal of Alloys and Compounds, 930, 167423.
https://doi.org/10.1016/j.jallcom.2022.167423
Ahmetović S, Vasiljević ZŽ, Rajić V, Bartolić D, Novaković M, Tadić NB, Cvjetićanin N, Nikolić MV. Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers. in Journal of Alloys and Compounds. 2023;930:167423.
doi:10.1016/j.jallcom.2022.167423 .
Ahmetović, Sanita, Vasiljević, Zorka Ž., Rajić, Vladimir, Bartolić, Dragana, Novaković, Mirjana, Tadić, Nenad B., Cvjetićanin, Nikola, Nikolić, Maria Vesna, "Examination of the doping effects of samarium (Sm3+) and zirconium (Zr4+) on the photocatalytic activity of TiO2 nanofibers" in Journal of Alloys and Compounds, 930 (2023):167423,
https://doi.org/10.1016/j.jallcom.2022.167423 . .

Gamma rays induced synthesis of graphene oxide/gold nanoparticle composites: structural and photothermal study

Kepić, Dejan P.; Stefanović, Anđela M.; Budimir, Milica; Pavlović, Vladimir B.; Bonasera, Aurelio; Scopelliti, Michelangelo; Todorović-Marković, Biljana

(2023)

TY  - JOUR
AU  - Kepić, Dejan P.
AU  - Stefanović, Anđela M.
AU  - Budimir, Milica
AU  - Pavlović, Vladimir B.
AU  - Bonasera, Aurelio
AU  - Scopelliti, Michelangelo
AU  - Todorović-Marković, Biljana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10426
AB  - Gamma irradiation provides an alternative pathway to conventional gold nanoparticle synthesis because it is simple, fast, and economical. Here, we employed gamma irradiation at low doses (1–20 kGy) to obtain gold nanoparticles (Au NPs) anchored onto graphene oxide (GO) sheets. GO was selected as a suitable platform for the nucleation and growth of Au NPs because of its large surface area and good dispersibility in water due to the presence of polar oxygen-containing functional groups in its structure. Gamma irradiation at all the applied doses led to the reduction of chloroauric acid and the formation of evenly distributed Au NPs at the GO surface, simultaneously causing the reduction of GO and partial restoration of the graphene structure. As-prepared Au NPs have predominately spheric shapes and the smallest nanoparticles were reported for the dose of 1 kGy. The increase in the irradiation dose caused either the growth of larger particles (5 and 10 kGy) or the broad distribution of particles’ sizes (20 kGy). All samples showed a temperature increase upon exposure to 800 nm laser and photothermal efficiency was the highest for the sample prepared at 20 kGy. © 2022 Elsevier Ltd
T2  - Radiation Physics and Chemistry
T1  - Gamma rays induced synthesis of graphene oxide/gold nanoparticle composites: structural and photothermal study
VL  - 202
DO  - 10.1016/j.radphyschem.2022.110545
ER  - 
@article{
author = "Kepić, Dejan P. and Stefanović, Anđela M. and Budimir, Milica and Pavlović, Vladimir B. and Bonasera, Aurelio and Scopelliti, Michelangelo and Todorović-Marković, Biljana",
year = "2023",
abstract = "Gamma irradiation provides an alternative pathway to conventional gold nanoparticle synthesis because it is simple, fast, and economical. Here, we employed gamma irradiation at low doses (1–20 kGy) to obtain gold nanoparticles (Au NPs) anchored onto graphene oxide (GO) sheets. GO was selected as a suitable platform for the nucleation and growth of Au NPs because of its large surface area and good dispersibility in water due to the presence of polar oxygen-containing functional groups in its structure. Gamma irradiation at all the applied doses led to the reduction of chloroauric acid and the formation of evenly distributed Au NPs at the GO surface, simultaneously causing the reduction of GO and partial restoration of the graphene structure. As-prepared Au NPs have predominately spheric shapes and the smallest nanoparticles were reported for the dose of 1 kGy. The increase in the irradiation dose caused either the growth of larger particles (5 and 10 kGy) or the broad distribution of particles’ sizes (20 kGy). All samples showed a temperature increase upon exposure to 800 nm laser and photothermal efficiency was the highest for the sample prepared at 20 kGy. © 2022 Elsevier Ltd",
journal = "Radiation Physics and Chemistry",
title = "Gamma rays induced synthesis of graphene oxide/gold nanoparticle composites: structural and photothermal study",
volume = "202",
doi = "10.1016/j.radphyschem.2022.110545"
}
Kepić, D. P., Stefanović, A. M., Budimir, M., Pavlović, V. B., Bonasera, A., Scopelliti, M.,& Todorović-Marković, B.. (2023). Gamma rays induced synthesis of graphene oxide/gold nanoparticle composites: structural and photothermal study. in Radiation Physics and Chemistry, 202.
https://doi.org/10.1016/j.radphyschem.2022.110545
Kepić DP, Stefanović AM, Budimir M, Pavlović VB, Bonasera A, Scopelliti M, Todorović-Marković B. Gamma rays induced synthesis of graphene oxide/gold nanoparticle composites: structural and photothermal study. in Radiation Physics and Chemistry. 2023;202.
doi:10.1016/j.radphyschem.2022.110545 .
Kepić, Dejan P., Stefanović, Anđela M., Budimir, Milica, Pavlović, Vladimir B., Bonasera, Aurelio, Scopelliti, Michelangelo, Todorović-Marković, Biljana, "Gamma rays induced synthesis of graphene oxide/gold nanoparticle composites: structural and photothermal study" in Radiation Physics and Chemistry, 202 (2023),
https://doi.org/10.1016/j.radphyschem.2022.110545 . .

Influence of data scaling and normalization on overall neural network performances in photoacoustics

Đorđević, Katarina Lj.; Jordović-Pavlović, Miroslava I.; Ćojbašić, Ž. M.; Galović, Slobodanka; Popović, Marica N.; Nešić, Mioljub V.; Markushev, Dragan D.

(2022)

TY  - JOUR
AU  - Đorđević, Katarina Lj.
AU  - Jordović-Pavlović, Miroslava I.
AU  - Ćojbašić, Ž. M.
AU  - Galović, Slobodanka
AU  - Popović, Marica N.
AU  - Nešić, Mioljub V.
AU  - Markushev, Dragan D.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10359
AB  - In this paper, the influence of the input and output data scaling and normalization on the neural network overall performances is investigated aimed at inverse problem-solving in photoacoustics of semiconductors. The logarithmic scaling of the photoacoustic signal amplitudes as input data and numerical scaling of the sample thermal parameters as output data are presented as useful tools trying to reach maximal network precision. Max and min–max normalizations to the input data are presented to change their numerical values in the dataset to common scales, without distorting differences. It was demonstrated in theory that the largest network prediction error of all targeted parameters is obtained by a network with non-scaled output data. Also, it was found out that the best network prediction was achieved with min–max normalization of the input data and network predicted output data scale within the range of [1–10]. Network training and prediction performances analyzed with experimental input data show that the benefits and improvements of input and output scaling and normalization are not guaranteed but are strongly dependent on a specific problem to be solved.
T2  - Optical and Quantum Electronics
T1  - Influence of data scaling and normalization on overall neural network performances in photoacoustics
VL  - 54
IS  - 8
SP  - 501
DO  - 10.1007/s11082-022-03799-1
ER  - 
@article{
author = "Đorđević, Katarina Lj. and Jordović-Pavlović, Miroslava I. and Ćojbašić, Ž. M. and Galović, Slobodanka and Popović, Marica N. and Nešić, Mioljub V. and Markushev, Dragan D.",
year = "2022",
abstract = "In this paper, the influence of the input and output data scaling and normalization on the neural network overall performances is investigated aimed at inverse problem-solving in photoacoustics of semiconductors. The logarithmic scaling of the photoacoustic signal amplitudes as input data and numerical scaling of the sample thermal parameters as output data are presented as useful tools trying to reach maximal network precision. Max and min–max normalizations to the input data are presented to change their numerical values in the dataset to common scales, without distorting differences. It was demonstrated in theory that the largest network prediction error of all targeted parameters is obtained by a network with non-scaled output data. Also, it was found out that the best network prediction was achieved with min–max normalization of the input data and network predicted output data scale within the range of [1–10]. Network training and prediction performances analyzed with experimental input data show that the benefits and improvements of input and output scaling and normalization are not guaranteed but are strongly dependent on a specific problem to be solved.",
journal = "Optical and Quantum Electronics",
title = "Influence of data scaling and normalization on overall neural network performances in photoacoustics",
volume = "54",
number = "8",
pages = "501",
doi = "10.1007/s11082-022-03799-1"
}
Đorđević, K. Lj., Jordović-Pavlović, M. I., Ćojbašić, Ž. M., Galović, S., Popović, M. N., Nešić, M. V.,& Markushev, D. D.. (2022). Influence of data scaling and normalization on overall neural network performances in photoacoustics. in Optical and Quantum Electronics, 54(8), 501.
https://doi.org/10.1007/s11082-022-03799-1
Đorđević KL, Jordović-Pavlović MI, Ćojbašić ŽM, Galović S, Popović MN, Nešić MV, Markushev DD. Influence of data scaling and normalization on overall neural network performances in photoacoustics. in Optical and Quantum Electronics. 2022;54(8):501.
doi:10.1007/s11082-022-03799-1 .
Đorđević, Katarina Lj., Jordović-Pavlović, Miroslava I., Ćojbašić, Ž. M., Galović, Slobodanka, Popović, Marica N., Nešić, Mioljub V., Markushev, Dragan D., "Influence of data scaling and normalization on overall neural network performances in photoacoustics" in Optical and Quantum Electronics, 54, no. 8 (2022):501,
https://doi.org/10.1007/s11082-022-03799-1 . .
1

Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil

Đorđević, Кatarina Lj.; Galović, Slobodanka; Popović, Marica N.; Nešić, Mioljub V.; Stanimirović, Ivanka P.; Stanimirović, Zdravko I.; Markushev, Dragan D.

(2022)

TY  - JOUR
AU  - Đorđević, Кatarina Lj.
AU  - Galović, Slobodanka
AU  - Popović, Marica N.
AU  - Nešić, Mioljub V.
AU  - Stanimirović, Ivanka P.
AU  - Stanimirović, Zdravko I.
AU  - Markushev, Dragan D.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10364
AB  - The objective of this paper is to present methodology of the precise and reliable determination of thermal diffusivity and linear coefficient of thermal expansion of the photoacoustic signal recorded (obtained) using open photoacoustic cell where thickness of the sample served as a control parameter. The methodology was based on the application of neural networks that were trained on numerical experiments and optimized by adding Gaussian noise to the training base that corresponded in percentage to maximum measurement uncertainty. By comparing the predictions of the neural network with theoretical fitting curve for experimental results for the aluminum sample that was 197 μm thick, it was shown that the proposed methodology achieves high precision in the determination of thermoelastic and geometrical properties of the sample.
T2  - Measurement
T1  - Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil
SP  - 111537
DO  - 10.1016/j.measurement.2022.111537
ER  - 
@article{
author = "Đorđević, Кatarina Lj. and Galović, Slobodanka and Popović, Marica N. and Nešić, Mioljub V. and Stanimirović, Ivanka P. and Stanimirović, Zdravko I. and Markushev, Dragan D.",
year = "2022",
abstract = "The objective of this paper is to present methodology of the precise and reliable determination of thermal diffusivity and linear coefficient of thermal expansion of the photoacoustic signal recorded (obtained) using open photoacoustic cell where thickness of the sample served as a control parameter. The methodology was based on the application of neural networks that were trained on numerical experiments and optimized by adding Gaussian noise to the training base that corresponded in percentage to maximum measurement uncertainty. By comparing the predictions of the neural network with theoretical fitting curve for experimental results for the aluminum sample that was 197 μm thick, it was shown that the proposed methodology achieves high precision in the determination of thermoelastic and geometrical properties of the sample.",
journal = "Measurement",
title = "Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil",
pages = "111537",
doi = "10.1016/j.measurement.2022.111537"
}
Đorđević, К. Lj., Galović, S., Popović, M. N., Nešić, M. V., Stanimirović, I. P., Stanimirović, Z. I.,& Markushev, D. D.. (2022). Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil. in Measurement, 111537.
https://doi.org/10.1016/j.measurement.2022.111537
Đorđević КL, Galović S, Popović MN, Nešić MV, Stanimirović IP, Stanimirović ZI, Markushev DD. Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil. in Measurement. 2022;:111537.
doi:10.1016/j.measurement.2022.111537 .
Đorđević, Кatarina Lj., Galović, Slobodanka, Popović, Marica N., Nešić, Mioljub V., Stanimirović, Ivanka P., Stanimirović, Zdravko I., Markushev, Dragan D., "Use neural network in photoacoustic measurement of thermoelastic properties of aluminum foil" in Measurement (2022):111537,
https://doi.org/10.1016/j.measurement.2022.111537 . .

Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform

Arsić, Biljana; Barber, Jill; Čikoš, Ana; Kadirvel, Manikandan; Kostić, Emilija; McBain, Andrew J.; Milićević, Jelena; Oates, Angela; Regan, Andrew

(2022)

TY  - JOUR
AU  - Arsić, Biljana
AU  - Barber, Jill
AU  - Čikoš, Ana
AU  - Kadirvel, Manikandan
AU  - Kostić, Emilija
AU  - McBain, Andrew J.
AU  - Milićević, Jelena
AU  - Oates, Angela
AU  - Regan, Andrew
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10502
AB  - Although many antibiotics are active against Gram-positive bacteria, fewer also show activity against Gram-negative bacteria. Here, we present a combination of in silico (electron ion-interaction potential, molecular docking, ADMET), NMR, and microbiological investigations of selected macrolides (14-membered, 15-membered, and 16-membered), aiming to discover the pattern of design for macrolides active against Gram-negative bacteria. Although the conformational studies of 14-membered and 15-membered macrolides are abundant in the literature, 16-membered macrolides, and their most prominent representative tylosin A, have received relatively little research attention. We therefore report the complete 1H and 13C NMR assignment of tylosin A in deuterated chloroform, as well as its 3D solution structure determined through molecular modelling (conformational search) and 2D ROESY NMR. Additionally, due to the degradation of tylosin A in deuterated chloroform, other species were also detected in 1D and 2D NMR spectra. We additionally studied the anti-bacterial activity of tylosin A and B against selected Gram-positive and Gram-negative bacteria.
T2  - Molecules
T1  - Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform
VL  - 27
IS  - 21
SP  - 7280
DO  - 10.3390/molecules27217280
ER  - 
@article{
author = "Arsić, Biljana and Barber, Jill and Čikoš, Ana and Kadirvel, Manikandan and Kostić, Emilija and McBain, Andrew J. and Milićević, Jelena and Oates, Angela and Regan, Andrew",
year = "2022",
abstract = "Although many antibiotics are active against Gram-positive bacteria, fewer also show activity against Gram-negative bacteria. Here, we present a combination of in silico (electron ion-interaction potential, molecular docking, ADMET), NMR, and microbiological investigations of selected macrolides (14-membered, 15-membered, and 16-membered), aiming to discover the pattern of design for macrolides active against Gram-negative bacteria. Although the conformational studies of 14-membered and 15-membered macrolides are abundant in the literature, 16-membered macrolides, and their most prominent representative tylosin A, have received relatively little research attention. We therefore report the complete 1H and 13C NMR assignment of tylosin A in deuterated chloroform, as well as its 3D solution structure determined through molecular modelling (conformational search) and 2D ROESY NMR. Additionally, due to the degradation of tylosin A in deuterated chloroform, other species were also detected in 1D and 2D NMR spectra. We additionally studied the anti-bacterial activity of tylosin A and B against selected Gram-positive and Gram-negative bacteria.",
journal = "Molecules",
title = "Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform",
volume = "27",
number = "21",
pages = "7280",
doi = "10.3390/molecules27217280"
}
Arsić, B., Barber, J., Čikoš, A., Kadirvel, M., Kostić, E., McBain, A. J., Milićević, J., Oates, A.,& Regan, A.. (2022). Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform. in Molecules, 27(21), 7280.
https://doi.org/10.3390/molecules27217280
Arsić B, Barber J, Čikoš A, Kadirvel M, Kostić E, McBain AJ, Milićević J, Oates A, Regan A. Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform. in Molecules. 2022;27(21):7280.
doi:10.3390/molecules27217280 .
Arsić, Biljana, Barber, Jill, Čikoš, Ana, Kadirvel, Manikandan, Kostić, Emilija, McBain, Andrew J., Milićević, Jelena, Oates, Angela, Regan, Andrew, "Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform" in Molecules, 27, no. 21 (2022):7280,
https://doi.org/10.3390/molecules27217280 . .

Enhancement of Methylene Blue Photodegradation Rate Using Laser Synthesized Ag-Doped ZnO Nanoparticles

Blažeka, Damjan; Radičić, Rafaela; Maletić, Dejan; Živković, Sanja; Momčilović, Miloš; Krstulović, Nikša

(2022)

TY  - JOUR
AU  - Blažeka, Damjan
AU  - Radičić, Rafaela
AU  - Maletić, Dejan
AU  - Živković, Sanja
AU  - Momčilović, Miloš
AU  - Krstulović, Nikša
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10407
AB  - In this work, Ag-doped ZnO nanoparticles are obtained via pulsed laser ablation of the Ag-coated ZnO target in water. The ratio of Ag dopant in ZnO nanoparticles strongly depends on the thickness of the Ag layer at the ZnO target. Synthesized nanoparticles were characterized by XRD, XPS, SEM, EDS, ICP-OES, and UV–VIS spectrophotometry to obtain their crystal structure, elemental composition, morphology and size distribution, mass concentration, and optical properties, respectively. The photocatalytic studies showed photodegradation of methylene blue (MB) under UV irradiation. Different ratios of Ag dopant in ZnO nanoparticles influence the photodegradation rate. The ZnO nanoparticles doped with 0.32% silver show the most efficient photodegradation rate, with the chemical reaction constant of 0.0233 min−1. It exhibits an almost twice as large photodegradation rate compared to pure ZnO nanoparticles, showing the doping effect on the photocatalytic activity.
T2  - Nanomaterials
T1  - Enhancement of Methylene Blue Photodegradation Rate Using Laser Synthesized Ag-Doped ZnO Nanoparticles
VL  - 12
IS  - 15
SP  - 2677
DO  - 10.3390/nano12152677
ER  - 
@article{
author = "Blažeka, Damjan and Radičić, Rafaela and Maletić, Dejan and Živković, Sanja and Momčilović, Miloš and Krstulović, Nikša",
year = "2022",
abstract = "In this work, Ag-doped ZnO nanoparticles are obtained via pulsed laser ablation of the Ag-coated ZnO target in water. The ratio of Ag dopant in ZnO nanoparticles strongly depends on the thickness of the Ag layer at the ZnO target. Synthesized nanoparticles were characterized by XRD, XPS, SEM, EDS, ICP-OES, and UV–VIS spectrophotometry to obtain their crystal structure, elemental composition, morphology and size distribution, mass concentration, and optical properties, respectively. The photocatalytic studies showed photodegradation of methylene blue (MB) under UV irradiation. Different ratios of Ag dopant in ZnO nanoparticles influence the photodegradation rate. The ZnO nanoparticles doped with 0.32% silver show the most efficient photodegradation rate, with the chemical reaction constant of 0.0233 min−1. It exhibits an almost twice as large photodegradation rate compared to pure ZnO nanoparticles, showing the doping effect on the photocatalytic activity.",
journal = "Nanomaterials",
title = "Enhancement of Methylene Blue Photodegradation Rate Using Laser Synthesized Ag-Doped ZnO Nanoparticles",
volume = "12",
number = "15",
pages = "2677",
doi = "10.3390/nano12152677"
}
Blažeka, D., Radičić, R., Maletić, D., Živković, S., Momčilović, M.,& Krstulović, N.. (2022). Enhancement of Methylene Blue Photodegradation Rate Using Laser Synthesized Ag-Doped ZnO Nanoparticles. in Nanomaterials, 12(15), 2677.
https://doi.org/10.3390/nano12152677
Blažeka D, Radičić R, Maletić D, Živković S, Momčilović M, Krstulović N. Enhancement of Methylene Blue Photodegradation Rate Using Laser Synthesized Ag-Doped ZnO Nanoparticles. in Nanomaterials. 2022;12(15):2677.
doi:10.3390/nano12152677 .
Blažeka, Damjan, Radičić, Rafaela, Maletić, Dejan, Živković, Sanja, Momčilović, Miloš, Krstulović, Nikša, "Enhancement of Methylene Blue Photodegradation Rate Using Laser Synthesized Ag-Doped ZnO Nanoparticles" in Nanomaterials, 12, no. 15 (2022):2677,
https://doi.org/10.3390/nano12152677 . .
1

Application of the Hazardous Waste Vitreous Enamel Generated in the Production Process of Heating Devices as a Partial Replacement for Cement

Kragović, Milan; Stojmenović, Marija; Ristić, Nenad; Milićević, Sonja; Živković, Sanja; Liu, Shanke; Gulicovski, Jelena

(2022)

TY  - JOUR
AU  - Kragović, Milan
AU  - Stojmenović, Marija
AU  - Ristić, Nenad
AU  - Milićević, Sonja
AU  - Živković, Sanja
AU  - Liu, Shanke
AU  - Gulicovski, Jelena
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10414
AB  - Solving problems with hazardous waste materials is of crucial importance today. In the presented study, the application of waste vitreous enamel as a cement replacement up to 30% in mortar and concrete production was investigated. The chemical and physical-chemical characterization of the starting material was performed, as well as a leaching test and physical-mechanical characterization of mortar and concrete mixes. Obtained results showed that, due to its chemical composition, the vitreous enamel used must be classified as hazardous waste. At the same time, it possesses pozzolanic properties and satisfies minimal criteria for use as a cement replacement. Testing mortars and concrete mixes indicate that waste vitreous enamel can be applied as a construction material for cement replacement in the maximal amount of 20%. The leaching test was performed in accordance with international standard EN 12457-2 on hardened mortar with a maximal cement replacement of 20%. The results showed that there was no significant release of toxic elements, i.e., that the practical application of hazardous waste vitreous enamel in the construction industry may be fully in line with environmental standards.
T2  - Buildings
T1  - Application of the Hazardous Waste Vitreous Enamel Generated in the Production Process of Heating Devices as a Partial Replacement for Cement
VL  - 12
IS  - 8
SP  - 1287
DO  - 10.3390/buildings12081287
ER  - 
@article{
author = "Kragović, Milan and Stojmenović, Marija and Ristić, Nenad and Milićević, Sonja and Živković, Sanja and Liu, Shanke and Gulicovski, Jelena",
year = "2022",
abstract = "Solving problems with hazardous waste materials is of crucial importance today. In the presented study, the application of waste vitreous enamel as a cement replacement up to 30% in mortar and concrete production was investigated. The chemical and physical-chemical characterization of the starting material was performed, as well as a leaching test and physical-mechanical characterization of mortar and concrete mixes. Obtained results showed that, due to its chemical composition, the vitreous enamel used must be classified as hazardous waste. At the same time, it possesses pozzolanic properties and satisfies minimal criteria for use as a cement replacement. Testing mortars and concrete mixes indicate that waste vitreous enamel can be applied as a construction material for cement replacement in the maximal amount of 20%. The leaching test was performed in accordance with international standard EN 12457-2 on hardened mortar with a maximal cement replacement of 20%. The results showed that there was no significant release of toxic elements, i.e., that the practical application of hazardous waste vitreous enamel in the construction industry may be fully in line with environmental standards.",
journal = "Buildings",
title = "Application of the Hazardous Waste Vitreous Enamel Generated in the Production Process of Heating Devices as a Partial Replacement for Cement",
volume = "12",
number = "8",
pages = "1287",
doi = "10.3390/buildings12081287"
}
Kragović, M., Stojmenović, M., Ristić, N., Milićević, S., Živković, S., Liu, S.,& Gulicovski, J.. (2022). Application of the Hazardous Waste Vitreous Enamel Generated in the Production Process of Heating Devices as a Partial Replacement for Cement. in Buildings, 12(8), 1287.
https://doi.org/10.3390/buildings12081287
Kragović M, Stojmenović M, Ristić N, Milićević S, Živković S, Liu S, Gulicovski J. Application of the Hazardous Waste Vitreous Enamel Generated in the Production Process of Heating Devices as a Partial Replacement for Cement. in Buildings. 2022;12(8):1287.
doi:10.3390/buildings12081287 .
Kragović, Milan, Stojmenović, Marija, Ristić, Nenad, Milićević, Sonja, Živković, Sanja, Liu, Shanke, Gulicovski, Jelena, "Application of the Hazardous Waste Vitreous Enamel Generated in the Production Process of Heating Devices as a Partial Replacement for Cement" in Buildings, 12, no. 8 (2022):1287,
https://doi.org/10.3390/buildings12081287 . .
1

Removal of heavy metals from aqueous media by sunflower husk: A comparative study of biosorption efficiency by using ICP-OES and LIBS

Radenković, Marina; Momčilović, Miloš; Petrović, Jelena; Mraković, Ana; Relić, Dubravka; Popović, Aleksandar; Živković, Sanja

(2022)

TY  - JOUR
AU  - Radenković, Marina
AU  - Momčilović, Miloš
AU  - Petrović, Jelena
AU  - Mraković, Ana
AU  - Relić, Dubravka
AU  - Popović, Aleksandar
AU  - Živković, Sanja
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10467
AB  - Presented research aimed to develop an alternative approach for the estimation of biosorption capability of sunflower husk. The acid-pretreated sunflower biomass was characterized by scanning electron microscopy combined with energy dispersive X-Ray spectroscopy (SEM-EDX) analysis and Fourier transform infrared (FTIR) spectroscopy. Biosorption efficiency has been evaluated using inductively coupled plasma optical emission spectroscopy (ICP-OES) and laser-induced breakdown spectroscopy (LIBS). The adsorption capacity of the adsorbent was determined as the function of the pH of the solution, the initial concentration of heavy metal solutions, and contact time. The optimal conditions were achieved after 15 min of contact at pH 6, while the percentage of the removal was from 80.0–98.7 %, depending on the element. The results obtained from the kinetic and isotherm studies show that maximum adsorption of ions was quickly reached and followed the pseudo-second-order kinetic model. Real samples were tested and obtained Ni values by LIBS method were 3100±200 and 1240±100 mg kg-1, while estimated values by the ICP-OES were 2995±20 and 1130±10 mg kg-1, respectively. The obtained results prove that LIBS method can be used as a “green alternative” for the evaluation of biosorption efficiency.
T2  - Journal of the Serbian Chemical Society
T1  - Removal of heavy metals from aqueous media by sunflower husk: A comparative study of biosorption efficiency by using ICP-OES and LIBS
VL  - 87
IS  - 7-8
SP  - 939
EP  - 952
DO  - 10.2298/JSC220105022R
ER  - 
@article{
author = "Radenković, Marina and Momčilović, Miloš and Petrović, Jelena and Mraković, Ana and Relić, Dubravka and Popović, Aleksandar and Živković, Sanja",
year = "2022",
abstract = "Presented research aimed to develop an alternative approach for the estimation of biosorption capability of sunflower husk. The acid-pretreated sunflower biomass was characterized by scanning electron microscopy combined with energy dispersive X-Ray spectroscopy (SEM-EDX) analysis and Fourier transform infrared (FTIR) spectroscopy. Biosorption efficiency has been evaluated using inductively coupled plasma optical emission spectroscopy (ICP-OES) and laser-induced breakdown spectroscopy (LIBS). The adsorption capacity of the adsorbent was determined as the function of the pH of the solution, the initial concentration of heavy metal solutions, and contact time. The optimal conditions were achieved after 15 min of contact at pH 6, while the percentage of the removal was from 80.0–98.7 %, depending on the element. The results obtained from the kinetic and isotherm studies show that maximum adsorption of ions was quickly reached and followed the pseudo-second-order kinetic model. Real samples were tested and obtained Ni values by LIBS method were 3100±200 and 1240±100 mg kg-1, while estimated values by the ICP-OES were 2995±20 and 1130±10 mg kg-1, respectively. The obtained results prove that LIBS method can be used as a “green alternative” for the evaluation of biosorption efficiency.",
journal = "Journal of the Serbian Chemical Society",
title = "Removal of heavy metals from aqueous media by sunflower husk: A comparative study of biosorption efficiency by using ICP-OES and LIBS",
volume = "87",
number = "7-8",
pages = "939-952",
doi = "10.2298/JSC220105022R"
}
Radenković, M., Momčilović, M., Petrović, J., Mraković, A., Relić, D., Popović, A.,& Živković, S.. (2022). Removal of heavy metals from aqueous media by sunflower husk: A comparative study of biosorption efficiency by using ICP-OES and LIBS. in Journal of the Serbian Chemical Society, 87(7-8), 939-952.
https://doi.org/10.2298/JSC220105022R
Radenković M, Momčilović M, Petrović J, Mraković A, Relić D, Popović A, Živković S. Removal of heavy metals from aqueous media by sunflower husk: A comparative study of biosorption efficiency by using ICP-OES and LIBS. in Journal of the Serbian Chemical Society. 2022;87(7-8):939-952.
doi:10.2298/JSC220105022R .
Radenković, Marina, Momčilović, Miloš, Petrović, Jelena, Mraković, Ana, Relić, Dubravka, Popović, Aleksandar, Živković, Sanja, "Removal of heavy metals from aqueous media by sunflower husk: A comparative study of biosorption efficiency by using ICP-OES and LIBS" in Journal of the Serbian Chemical Society, 87, no. 7-8 (2022):939-952,
https://doi.org/10.2298/JSC220105022R . .

Picosecond laser-assisted synthesis of silver nanoparticles with high practical application as electroanalytical sensor

Ognjanović, Miloš; Nikolić, Katarina M.; Radenković, Marina; Lolić, Aleksandar Đ.; Stanković, Dalibor M.; Živković, Sanja

(2022)

TY  - JOUR
AU  - Ognjanović, Miloš
AU  - Nikolić, Katarina M.
AU  - Radenković, Marina
AU  - Lolić, Aleksandar Đ.
AU  - Stanković, Dalibor M.
AU  - Živković, Sanja
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10501
AB  - Gallic acid (GA) is one of the most important and present natural phenolic compounds due to its well-known biological properties, and its detection and monitoring is of great importance. Silver nanoparticles (AgNPs) are one of the most studied metallic nanomaterials used in various fields, from biomedical applications to electrochemical sensing devices. In this work, we used the pulsed laser ablation technique in liquid for the one-step preparation of nanoparticles of silver from a pure silver plate base in N,N-dimethylformamide. Obtained nanomaterial was characterized using morphological and electrochemical methods and used for modification of screen-printed carbon electrodes (SPCE). Successful immobilization at the surface is confirmed using the surface profiling method. A newly obtained sensor was used for the detection of GA. After parameters optimization, a differential pulse voltammetric protocol was developed, using two approaches - concentration vs. current (GA determination) and peak area vs. current (estimation of the antioxidant capacity). For the first approach sensor linearity was found to be in the range from 0.50 µM to 10 µM, with the limit of detection (LOD) of 0.16 µM and limit of quantification (LOQ) of 0.50 µM. In the second system operating linear range was the same, while LOD and LOQ were 0.11 µM and 0.34 µM, respectively. Practical application of the method was tested using two approaches: direct measurement of gallic acid in biological fluids and estimation of the antioxidant capacity and food quality purpose.
T2  - Surfaces and Interfaces
T1  - Picosecond laser-assisted synthesis of silver nanoparticles with high practical application as electroanalytical sensor
VL  - 35
SP  - 102464
DO  - 10.1016/j.surfin.2022.102464
ER  - 
@article{
author = "Ognjanović, Miloš and Nikolić, Katarina M. and Radenković, Marina and Lolić, Aleksandar Đ. and Stanković, Dalibor M. and Živković, Sanja",
year = "2022",
abstract = "Gallic acid (GA) is one of the most important and present natural phenolic compounds due to its well-known biological properties, and its detection and monitoring is of great importance. Silver nanoparticles (AgNPs) are one of the most studied metallic nanomaterials used in various fields, from biomedical applications to electrochemical sensing devices. In this work, we used the pulsed laser ablation technique in liquid for the one-step preparation of nanoparticles of silver from a pure silver plate base in N,N-dimethylformamide. Obtained nanomaterial was characterized using morphological and electrochemical methods and used for modification of screen-printed carbon electrodes (SPCE). Successful immobilization at the surface is confirmed using the surface profiling method. A newly obtained sensor was used for the detection of GA. After parameters optimization, a differential pulse voltammetric protocol was developed, using two approaches - concentration vs. current (GA determination) and peak area vs. current (estimation of the antioxidant capacity). For the first approach sensor linearity was found to be in the range from 0.50 µM to 10 µM, with the limit of detection (LOD) of 0.16 µM and limit of quantification (LOQ) of 0.50 µM. In the second system operating linear range was the same, while LOD and LOQ were 0.11 µM and 0.34 µM, respectively. Practical application of the method was tested using two approaches: direct measurement of gallic acid in biological fluids and estimation of the antioxidant capacity and food quality purpose.",
journal = "Surfaces and Interfaces",
title = "Picosecond laser-assisted synthesis of silver nanoparticles with high practical application as electroanalytical sensor",
volume = "35",
pages = "102464",
doi = "10.1016/j.surfin.2022.102464"
}
Ognjanović, M., Nikolić, K. M., Radenković, M., Lolić, A. Đ., Stanković, D. M.,& Živković, S.. (2022). Picosecond laser-assisted synthesis of silver nanoparticles with high practical application as electroanalytical sensor. in Surfaces and Interfaces, 35, 102464.
https://doi.org/10.1016/j.surfin.2022.102464
Ognjanović M, Nikolić KM, Radenković M, Lolić AĐ, Stanković DM, Živković S. Picosecond laser-assisted synthesis of silver nanoparticles with high practical application as electroanalytical sensor. in Surfaces and Interfaces. 2022;35:102464.
doi:10.1016/j.surfin.2022.102464 .
Ognjanović, Miloš, Nikolić, Katarina M., Radenković, Marina, Lolić, Aleksandar Đ., Stanković, Dalibor M., Živković, Sanja, "Picosecond laser-assisted synthesis of silver nanoparticles with high practical application as electroanalytical sensor" in Surfaces and Interfaces, 35 (2022):102464,
https://doi.org/10.1016/j.surfin.2022.102464 . .

Co(III), Ni(II) and Cu(II) complexes with a tetradentate Schiff base ligand: synthesis, characterization, electrochemical behavior, binding assessment and in vitro cytotoxicity

Mirković, Marija D.; Radović, Magdalena; Stanković, Dalibor M.; Vranješ-Đurić, Sanja; Janković, Drina; Petrović, Djordje; Mihajlović-Lalić, Ljiljana E.; Prijović, Željko; Milanović, Zorana

(2022)

TY  - JOUR
AU  - Mirković, Marija D.
AU  - Radović, Magdalena
AU  - Stanković, Dalibor M.
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Petrović, Djordje
AU  - Mihajlović-Lalić, Ljiljana E.
AU  - Prijović, Željko
AU  - Milanović, Zorana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10169
AB  - Two new Schiff base cobalt(III) ([Co(LH)Cl2], 1) and nickel(II) ([Ni(LH)ClO4], 2) complexes with a diimine-dioxime ligand, (4,9-diaza-3,10-diethyl-3,9-dodecadiene-2,11-dione bis oxime (LH2)), were synthesized and characterized. The compounds were obtained in MeOH from corresponding metal salts and LH2 in molar ratio 1:1 and further characterized by mass spectrometry, IR spectroscopy, electrochemistry, and elemental analysis. Previously reported copper(II) analog ([Cu2(LH)2]·(ClO4)2, 3) was joined to 1 and 2, and the three metal analogs, 1–3, were further investigated in terms of their electrochemical behavior. Binding studies of the complexes with deoxyribonucleic acid (DNA) and human serum albumin (HSA) were carried out using both spectrophotometric and electrochemical methods. All three complexes exhibit binding affinity towards the DNA chain through intercalative interactions. The binding reaction with HSA showed for 1 and 3 decrease in the peak current obtained in the case of complexes before the addition of HSA, while the Ni complex–HSA possesses the same electroactivity as starting complex. The cytotoxicity of LH2 as well as its metal complexes, and cisplatin were evaluated on CT-26 mouse colon carcinoma and human LS174T cancer cell lines employing MTT assay. The copper(II) complex exhibited very promising anticancer activity compared with cisplatin.
T2  - Journal of Coordination Chemistry
T1  - Co(III), Ni(II) and Cu(II) complexes with a tetradentate Schiff base ligand: synthesis, characterization, electrochemical behavior, binding assessment and in vitro cytotoxicity
SP  - 1
EP  - 14
DO  - 10.1080/00958972.2022.2032683
ER  - 
@article{
author = "Mirković, Marija D. and Radović, Magdalena and Stanković, Dalibor M. and Vranješ-Đurić, Sanja and Janković, Drina and Petrović, Djordje and Mihajlović-Lalić, Ljiljana E. and Prijović, Željko and Milanović, Zorana",
year = "2022",
abstract = "Two new Schiff base cobalt(III) ([Co(LH)Cl2], 1) and nickel(II) ([Ni(LH)ClO4], 2) complexes with a diimine-dioxime ligand, (4,9-diaza-3,10-diethyl-3,9-dodecadiene-2,11-dione bis oxime (LH2)), were synthesized and characterized. The compounds were obtained in MeOH from corresponding metal salts and LH2 in molar ratio 1:1 and further characterized by mass spectrometry, IR spectroscopy, electrochemistry, and elemental analysis. Previously reported copper(II) analog ([Cu2(LH)2]·(ClO4)2, 3) was joined to 1 and 2, and the three metal analogs, 1–3, were further investigated in terms of their electrochemical behavior. Binding studies of the complexes with deoxyribonucleic acid (DNA) and human serum albumin (HSA) were carried out using both spectrophotometric and electrochemical methods. All three complexes exhibit binding affinity towards the DNA chain through intercalative interactions. The binding reaction with HSA showed for 1 and 3 decrease in the peak current obtained in the case of complexes before the addition of HSA, while the Ni complex–HSA possesses the same electroactivity as starting complex. The cytotoxicity of LH2 as well as its metal complexes, and cisplatin were evaluated on CT-26 mouse colon carcinoma and human LS174T cancer cell lines employing MTT assay. The copper(II) complex exhibited very promising anticancer activity compared with cisplatin.",
journal = "Journal of Coordination Chemistry",
title = "Co(III), Ni(II) and Cu(II) complexes with a tetradentate Schiff base ligand: synthesis, characterization, electrochemical behavior, binding assessment and in vitro cytotoxicity",
pages = "1-14",
doi = "10.1080/00958972.2022.2032683"
}
Mirković, M. D., Radović, M., Stanković, D. M., Vranješ-Đurić, S., Janković, D., Petrović, D., Mihajlović-Lalić, L. E., Prijović, Ž.,& Milanović, Z.. (2022). Co(III), Ni(II) and Cu(II) complexes with a tetradentate Schiff base ligand: synthesis, characterization, electrochemical behavior, binding assessment and in vitro cytotoxicity. in Journal of Coordination Chemistry, 1-14.
https://doi.org/10.1080/00958972.2022.2032683
Mirković MD, Radović M, Stanković DM, Vranješ-Đurić S, Janković D, Petrović D, Mihajlović-Lalić LE, Prijović Ž, Milanović Z. Co(III), Ni(II) and Cu(II) complexes with a tetradentate Schiff base ligand: synthesis, characterization, electrochemical behavior, binding assessment and in vitro cytotoxicity. in Journal of Coordination Chemistry. 2022;:1-14.
doi:10.1080/00958972.2022.2032683 .
Mirković, Marija D., Radović, Magdalena, Stanković, Dalibor M., Vranješ-Đurić, Sanja, Janković, Drina, Petrović, Djordje, Mihajlović-Lalić, Ljiljana E., Prijović, Željko, Milanović, Zorana, "Co(III), Ni(II) and Cu(II) complexes with a tetradentate Schiff base ligand: synthesis, characterization, electrochemical behavior, binding assessment and in vitro cytotoxicity" in Journal of Coordination Chemistry (2022):1-14,
https://doi.org/10.1080/00958972.2022.2032683 . .
1
1

Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix

Đorđević, Neda O.; Stanisavljević, Nemanja; Todorović Vukotić, Nevena; Novović, Katarina; Žakula, Jelena; Stanković, Dalibor M.; Pajović, Snežana B.

(2022)

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Stanisavljević, Nemanja
AU  - Todorović Vukotić, Nevena
AU  - Novović, Katarina
AU  - Žakula, Jelena
AU  - Stanković, Dalibor M.
AU  - Pajović, Snežana B.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10353
AB  - The beneficial effect of moderate wine consumption is attributed to its micronutrients, especially polyphenols and largely depends on the digestion process. This work aimed to examine the influence of in vitro simulated digestion in the presence of complex food matrix on antioxidant and cytotoxic activity of red wine. The obtained results showed that total phenolic content of wine sample after in vitro digestion was higher compared to undigested wine, while the antioxidant activity of these samples was similar before and after digestion. Furthermore, it has been noticed that digested wine showed cytotoxic activity on SKBR3 breast adenocarcinoma cells near 20% after 72 h of treatment. This pioneering study that examined biological potential of in vitro digested wine in the presence of complex food matrix indicate that antioxidant and cytotoxic activity of red wine is preserved after digestion.
T2  - Natural Product Research
T1  - Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix
SP  - 1
EP  - 6
DO  - 10.1080/14786419.2022.2095380
ER  - 
@article{
author = "Đorđević, Neda O. and Stanisavljević, Nemanja and Todorović Vukotić, Nevena and Novović, Katarina and Žakula, Jelena and Stanković, Dalibor M. and Pajović, Snežana B.",
year = "2022",
abstract = "The beneficial effect of moderate wine consumption is attributed to its micronutrients, especially polyphenols and largely depends on the digestion process. This work aimed to examine the influence of in vitro simulated digestion in the presence of complex food matrix on antioxidant and cytotoxic activity of red wine. The obtained results showed that total phenolic content of wine sample after in vitro digestion was higher compared to undigested wine, while the antioxidant activity of these samples was similar before and after digestion. Furthermore, it has been noticed that digested wine showed cytotoxic activity on SKBR3 breast adenocarcinoma cells near 20% after 72 h of treatment. This pioneering study that examined biological potential of in vitro digested wine in the presence of complex food matrix indicate that antioxidant and cytotoxic activity of red wine is preserved after digestion.",
journal = "Natural Product Research",
title = "Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix",
pages = "1-6",
doi = "10.1080/14786419.2022.2095380"
}
Đorđević, N. O., Stanisavljević, N., Todorović Vukotić, N., Novović, K., Žakula, J., Stanković, D. M.,& Pajović, S. B.. (2022). Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix. in Natural Product Research, 1-6.
https://doi.org/10.1080/14786419.2022.2095380
Đorđević NO, Stanisavljević N, Todorović Vukotić N, Novović K, Žakula J, Stanković DM, Pajović SB. Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix. in Natural Product Research. 2022;:1-6.
doi:10.1080/14786419.2022.2095380 .
Đorđević, Neda O., Stanisavljević, Nemanja, Todorović Vukotić, Nevena, Novović, Katarina, Žakula, Jelena, Stanković, Dalibor M., Pajović, Snežana B., "Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix" in Natural Product Research (2022):1-6,
https://doi.org/10.1080/14786419.2022.2095380 . .
1
1

Silver distribution and binding mode as key determinants of the antimicrobial performance of iron oxide/silver nanocomposites

Šuljagić, Marija; Milenković, Milica; Uskoković, Vuk; Mirković, Miljana M.; Vrbica, Boško; Pavlović, Vladimir B.; Živković-Radovanović, Vukosava; Stanković, Dalibor M.; Anđelković, Ljubica

(2022)

TY  - JOUR
AU  - Šuljagić, Marija
AU  - Milenković, Milica
AU  - Uskoković, Vuk
AU  - Mirković, Miljana M.
AU  - Vrbica, Boško
AU  - Pavlović, Vladimir B.
AU  - Živković-Radovanović, Vukosava
AU  - Stanković, Dalibor M.
AU  - Anđelković, Ljubica
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10386
AB  - The emerging threat of bacterial resistance to antibiotics prompts the urgent search for biomaterials for the treatment of infectious disease. Here we report on the synthesis and characterization of a multiphasic nanocomposite comprising magnetic iron oxide and silver nanoparticles. The method of synthesis involved the combustion of a metalorganic complex and reduction of the silver ions that were exchanged and/or adsorbed on the surface of iron oxide. Different physical and chemical treatments coupled to the reduction process, including ultrasound and Lugol's iodine solution, respectively, homogenized the distribution of the silver nanoparticles on the iron oxide phase. Remarkably, using ascorbic acid as a reductant enhanced the magnetic properties of the material as a result of the reduction of the magnetic matrix alongside the silver cations. The treatment with ultrasound detached large amounts of silver from the iron oxide phase and resulted in the lowest amount of silver incorporated in the nanocomposite. Despite that, this treatment led to the highest antibacterial activity against both Gram-positive and Gram-negative strains, indicating that the homogeneity of the distribution of silver on the iron oxide matrix is a more important determinant of the antibacterial performance than the amount of silver incorporated in the material. At the same time, the treatment with Lugol's iodine equally increased the distribution homogeneity, but induced excessive ion exchange and crystal lattice substitutions, thereby adversely affecting the antibacterial performance. This has indicated that the mode of binding silver to iron oxide can compensate for the positive effects of homogeneous distribution with respect to the antibacterial performance.
T2  - Materials Today Communications
T1  - Silver distribution and binding mode as key determinants of the antimicrobial performance of iron oxide/silver nanocomposites
VL  - 32
SP  - 104157
DO  - 10.1016/j.mtcomm.2022.104157
ER  - 
@article{
author = "Šuljagić, Marija and Milenković, Milica and Uskoković, Vuk and Mirković, Miljana M. and Vrbica, Boško and Pavlović, Vladimir B. and Živković-Radovanović, Vukosava and Stanković, Dalibor M. and Anđelković, Ljubica",
year = "2022",
abstract = "The emerging threat of bacterial resistance to antibiotics prompts the urgent search for biomaterials for the treatment of infectious disease. Here we report on the synthesis and characterization of a multiphasic nanocomposite comprising magnetic iron oxide and silver nanoparticles. The method of synthesis involved the combustion of a metalorganic complex and reduction of the silver ions that were exchanged and/or adsorbed on the surface of iron oxide. Different physical and chemical treatments coupled to the reduction process, including ultrasound and Lugol's iodine solution, respectively, homogenized the distribution of the silver nanoparticles on the iron oxide phase. Remarkably, using ascorbic acid as a reductant enhanced the magnetic properties of the material as a result of the reduction of the magnetic matrix alongside the silver cations. The treatment with ultrasound detached large amounts of silver from the iron oxide phase and resulted in the lowest amount of silver incorporated in the nanocomposite. Despite that, this treatment led to the highest antibacterial activity against both Gram-positive and Gram-negative strains, indicating that the homogeneity of the distribution of silver on the iron oxide matrix is a more important determinant of the antibacterial performance than the amount of silver incorporated in the material. At the same time, the treatment with Lugol's iodine equally increased the distribution homogeneity, but induced excessive ion exchange and crystal lattice substitutions, thereby adversely affecting the antibacterial performance. This has indicated that the mode of binding silver to iron oxide can compensate for the positive effects of homogeneous distribution with respect to the antibacterial performance.",
journal = "Materials Today Communications",
title = "Silver distribution and binding mode as key determinants of the antimicrobial performance of iron oxide/silver nanocomposites",
volume = "32",
pages = "104157",
doi = "10.1016/j.mtcomm.2022.104157"
}
Šuljagić, M., Milenković, M., Uskoković, V., Mirković, M. M., Vrbica, B., Pavlović, V. B., Živković-Radovanović, V., Stanković, D. M.,& Anđelković, L.. (2022). Silver distribution and binding mode as key determinants of the antimicrobial performance of iron oxide/silver nanocomposites. in Materials Today Communications, 32, 104157.
https://doi.org/10.1016/j.mtcomm.2022.104157
Šuljagić M, Milenković M, Uskoković V, Mirković MM, Vrbica B, Pavlović VB, Živković-Radovanović V, Stanković DM, Anđelković L. Silver distribution and binding mode as key determinants of the antimicrobial performance of iron oxide/silver nanocomposites. in Materials Today Communications. 2022;32:104157.
doi:10.1016/j.mtcomm.2022.104157 .
Šuljagić, Marija, Milenković, Milica, Uskoković, Vuk, Mirković, Miljana M., Vrbica, Boško, Pavlović, Vladimir B., Živković-Radovanović, Vukosava, Stanković, Dalibor M., Anđelković, Ljubica, "Silver distribution and binding mode as key determinants of the antimicrobial performance of iron oxide/silver nanocomposites" in Materials Today Communications, 32 (2022):104157,
https://doi.org/10.1016/j.mtcomm.2022.104157 . .

Calculation of intersubband absorption in ZnO/ZnMgO asymmetric double quantum wells

Atić, Aleksandar; Vuković, Nikola N.; Radovanović, Jelena

(2022)

TY  - JOUR
AU  - Atić, Aleksandar
AU  - Vuković, Nikola N.
AU  - Radovanović, Jelena
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10450
AB  - ZnO based heterostructures have recently received increased research attention, related to the development of room temperature THz/MiR semiconductor devices. The potential for these applications stems from the combination of wide direct bandgap and high exciton binding energy. In this work, we focus on the intersubband transition between bound states in the conduction band, and apply self-consistent numerical modelling to a system of Schrödinger–Poisson equations to evaluate the electronics structure of coupled semiconductor quantum wells. We subsequently analyse the fractional optical absorption at room temperature, as it varies with layers’ thicknesses, doping density and external electric field magnitude.
T2  - Optical and Quantum Electronics
T1  - Calculation of intersubband absorption in ZnO/ZnMgO asymmetric double quantum wells
VL  - 54
IS  - 12
SP  - 810
DO  - 10.1007/s11082-022-04170-0
ER  - 
@article{
author = "Atić, Aleksandar and Vuković, Nikola N. and Radovanović, Jelena",
year = "2022",
abstract = "ZnO based heterostructures have recently received increased research attention, related to the development of room temperature THz/MiR semiconductor devices. The potential for these applications stems from the combination of wide direct bandgap and high exciton binding energy. In this work, we focus on the intersubband transition between bound states in the conduction band, and apply self-consistent numerical modelling to a system of Schrödinger–Poisson equations to evaluate the electronics structure of coupled semiconductor quantum wells. We subsequently analyse the fractional optical absorption at room temperature, as it varies with layers’ thicknesses, doping density and external electric field magnitude.",
journal = "Optical and Quantum Electronics",
title = "Calculation of intersubband absorption in ZnO/ZnMgO asymmetric double quantum wells",
volume = "54",
number = "12",
pages = "810",
doi = "10.1007/s11082-022-04170-0"
}
Atić, A., Vuković, N. N.,& Radovanović, J.. (2022). Calculation of intersubband absorption in ZnO/ZnMgO asymmetric double quantum wells. in Optical and Quantum Electronics, 54(12), 810.
https://doi.org/10.1007/s11082-022-04170-0
Atić A, Vuković NN, Radovanović J. Calculation of intersubband absorption in ZnO/ZnMgO asymmetric double quantum wells. in Optical and Quantum Electronics. 2022;54(12):810.
doi:10.1007/s11082-022-04170-0 .
Atić, Aleksandar, Vuković, Nikola N., Radovanović, Jelena, "Calculation of intersubband absorption in ZnO/ZnMgO asymmetric double quantum wells" in Optical and Quantum Electronics, 54, no. 12 (2022):810,
https://doi.org/10.1007/s11082-022-04170-0 . .

The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model

Dubljević, Olga; Ković, Vanja; Pavković, Željko; Mitić, Miloš; Pešić, Vesna

(2022)

TY  - JOUR
AU  - Dubljević, Olga
AU  - Ković, Vanja
AU  - Pavković, Željko
AU  - Mitić, Miloš
AU  - Pešić, Vesna
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10482
AB  - A potential relationship between unrestricted sucrose intake (USI), overweight, and emotional/behavioral control has not been well documented. We examined the influence of USI and having less sweetness than expected on body weight (BW), motor/exploratory, anxiety-like, and social dominant behavior in adult C57BL/6J male mice. Animals had free access to water (group 1) or 32% sucrose and water (sucrose groups 2–5) for 10 days. Then, group 2 remained with 32% sucrose while groups 3–5 were subjected to the downshift (24 h access to 4%, 8%, or 16% sucrose). All experimental groups were weighed and tested in the novel-open arena (NA), elevated plus maze (EPM), and tube tests to assess BW, motor/exploratory, anxiety-like, and social dominance behavior, respectively. USI did not influence animals’ BW but produced hyperactivity and anxiolytic-like behavior, which was evident in EPM but not in NA; the outcomes of the downshift were comparable. USI did not influence successes/wins in the tube test but altered emotions that drive the winning, favoring a less anxious behavioral phenotype; this was not evident in the downshifted groups. Observed findings suggest that USI promotes sensation-seeking and motivates dominance, without changing BW, while blunted emotional base of social dominance might be an early mark of the downshift.
T2  - Brain Sciences
T1  - The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model
VL  - 12
IS  - 10
SP  - 1332
DO  - 10.3390/brainsci12101332
ER  - 
@article{
author = "Dubljević, Olga and Ković, Vanja and Pavković, Željko and Mitić, Miloš and Pešić, Vesna",
year = "2022",
abstract = "A potential relationship between unrestricted sucrose intake (USI), overweight, and emotional/behavioral control has not been well documented. We examined the influence of USI and having less sweetness than expected on body weight (BW), motor/exploratory, anxiety-like, and social dominant behavior in adult C57BL/6J male mice. Animals had free access to water (group 1) or 32% sucrose and water (sucrose groups 2–5) for 10 days. Then, group 2 remained with 32% sucrose while groups 3–5 were subjected to the downshift (24 h access to 4%, 8%, or 16% sucrose). All experimental groups were weighed and tested in the novel-open arena (NA), elevated plus maze (EPM), and tube tests to assess BW, motor/exploratory, anxiety-like, and social dominance behavior, respectively. USI did not influence animals’ BW but produced hyperactivity and anxiolytic-like behavior, which was evident in EPM but not in NA; the outcomes of the downshift were comparable. USI did not influence successes/wins in the tube test but altered emotions that drive the winning, favoring a less anxious behavioral phenotype; this was not evident in the downshifted groups. Observed findings suggest that USI promotes sensation-seeking and motivates dominance, without changing BW, while blunted emotional base of social dominance might be an early mark of the downshift.",
journal = "Brain Sciences",
title = "The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model",
volume = "12",
number = "10",
pages = "1332",
doi = "10.3390/brainsci12101332"
}
Dubljević, O., Ković, V., Pavković, Ž., Mitić, M.,& Pešić, V.. (2022). The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model. in Brain Sciences, 12(10), 1332.
https://doi.org/10.3390/brainsci12101332
Dubljević O, Ković V, Pavković Ž, Mitić M, Pešić V. The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model. in Brain Sciences. 2022;12(10):1332.
doi:10.3390/brainsci12101332 .
Dubljević, Olga, Ković, Vanja, Pavković, Željko, Mitić, Miloš, Pešić, Vesna, "The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model" in Brain Sciences, 12, no. 10 (2022):1332,
https://doi.org/10.3390/brainsci12101332 . .

Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart

Bošković, Maja; Živković, Maja; Korićanac, Goran; Tepavčević, Snežana; Zec, Manja; Debeljak-Martačić, Jasmina; Stanković, Aleksandra

(2022)

TY  - JOUR
AU  - Bošković, Maja
AU  - Živković, Maja
AU  - Korićanac, Goran
AU  - Tepavčević, Snežana
AU  - Zec, Manja
AU  - Debeljak-Martačić, Jasmina
AU  - Stanković, Aleksandra
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10485
AB  - Increased fructose consumption has been linked with chronic inflammation and metabolic syndrome (MetS). Activation of the renin-angiotensin system (RAS) and NF-κB have been detected in MetS. Walnuts are a rich source of polyunsaturated omega-3 fatty acids (n-3 PUFA) that were suggested to exert anti-inflammatory effects related to cardio-metabolic health. We hypothesized that walnut supplementation has the capacity to revert unfavorable fructose-rich diet (FRD)-induced activation of cardiac RAS and NF-κB in male rats. Due to the lack of similar studies, we investigated the effects of walnut supplementation (6 weeks) on the expression of four RAS molecules (ACE, ACE2, AT1R, and AT2R) and NF-κB in rat heart after FRD (10% w/v, 9 weeks). In addition, we followed the changes in the n-6/n-3 PUFA ratio in the total pool of heart lipids after both treatments to elucidate the walnut effects on fatty acids in the heart. 36 animals (9 per group) participated in the experiment. FRD significantly increased the ACE protein level in the heart (p < 0.001). Walnut supplementation significantly increased the ACE2 protein level in the heart of FRD (p < 0.001). In addition, walnut supplementation showed a significant main effect on the arachidonic acid/eicosapentaenoic acid ratio (p = 0.004). Walnut supplementation significantly reduced this ratio, in comparison with both, the control group (C vs. FW, p < 0.05) and the FRD group (F vs. FW, p < 0.05). However, walnut treatment failed to revert the significant effect of fructose (p < 0.001) on the elevation of NF-κB protein level. Our results suggest a beneficial effect of walnut supplementation on ACE2 protein level and n-6/n-3 PUFA level in the heart of the animal model of MetS. Such results highlight the approach of omega-3-rich walnut supplementation in the stimulation of endogenous production of favorable molecules in the heart which could be an affordable nutritional treatment formaintenance of cardio-metabolic health.
T2  - Frontiers in Physiology
T1  - Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart
VL  - 13
DO  - 10.3389/fphys.2022.942459
ER  - 
@article{
author = "Bošković, Maja and Živković, Maja and Korićanac, Goran and Tepavčević, Snežana and Zec, Manja and Debeljak-Martačić, Jasmina and Stanković, Aleksandra",
year = "2022",
abstract = "Increased fructose consumption has been linked with chronic inflammation and metabolic syndrome (MetS). Activation of the renin-angiotensin system (RAS) and NF-κB have been detected in MetS. Walnuts are a rich source of polyunsaturated omega-3 fatty acids (n-3 PUFA) that were suggested to exert anti-inflammatory effects related to cardio-metabolic health. We hypothesized that walnut supplementation has the capacity to revert unfavorable fructose-rich diet (FRD)-induced activation of cardiac RAS and NF-κB in male rats. Due to the lack of similar studies, we investigated the effects of walnut supplementation (6 weeks) on the expression of four RAS molecules (ACE, ACE2, AT1R, and AT2R) and NF-κB in rat heart after FRD (10% w/v, 9 weeks). In addition, we followed the changes in the n-6/n-3 PUFA ratio in the total pool of heart lipids after both treatments to elucidate the walnut effects on fatty acids in the heart. 36 animals (9 per group) participated in the experiment. FRD significantly increased the ACE protein level in the heart (p < 0.001). Walnut supplementation significantly increased the ACE2 protein level in the heart of FRD (p < 0.001). In addition, walnut supplementation showed a significant main effect on the arachidonic acid/eicosapentaenoic acid ratio (p = 0.004). Walnut supplementation significantly reduced this ratio, in comparison with both, the control group (C vs. FW, p < 0.05) and the FRD group (F vs. FW, p < 0.05). However, walnut treatment failed to revert the significant effect of fructose (p < 0.001) on the elevation of NF-κB protein level. Our results suggest a beneficial effect of walnut supplementation on ACE2 protein level and n-6/n-3 PUFA level in the heart of the animal model of MetS. Such results highlight the approach of omega-3-rich walnut supplementation in the stimulation of endogenous production of favorable molecules in the heart which could be an affordable nutritional treatment formaintenance of cardio-metabolic health.",
journal = "Frontiers in Physiology",
title = "Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart",
volume = "13",
doi = "10.3389/fphys.2022.942459"
}
Bošković, M., Živković, M., Korićanac, G., Tepavčević, S., Zec, M., Debeljak-Martačić, J.,& Stanković, A.. (2022). Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart. in Frontiers in Physiology, 13.
https://doi.org/10.3389/fphys.2022.942459
Bošković M, Živković M, Korićanac G, Tepavčević S, Zec M, Debeljak-Martačić J, Stanković A. Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart. in Frontiers in Physiology. 2022;13.
doi:10.3389/fphys.2022.942459 .
Bošković, Maja, Živković, Maja, Korićanac, Goran, Tepavčević, Snežana, Zec, Manja, Debeljak-Martačić, Jasmina, Stanković, Aleksandra, "Walnut supplementation after fructose-rich diet is associated with a beneficial fatty acid ratio and increased ACE2 expression in the rat heart" in Frontiers in Physiology, 13 (2022),
https://doi.org/10.3389/fphys.2022.942459 . .

Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage

Radovanović, Jelena; Antonijević, Biljana; Ćurčić, Marijana; Baralić, Katarina; Kolarević, Stoimir; Bulat, Zorica; Đukić-Ćosić, Danijela; Buha-Đorđević, Aleksandra; Vuković-Gačić, Branka; Javorac, Dragana; Antonijević Miljaković, Evica; Carević, Momir; Mandinić, Zoran

(2022)

TY  - JOUR
AU  - Radovanović, Jelena
AU  - Antonijević, Biljana
AU  - Ćurčić, Marijana
AU  - Baralić, Katarina
AU  - Kolarević, Stoimir
AU  - Bulat, Zorica
AU  - Đukić-Ćosić, Danijela
AU  - Buha-Đorđević, Aleksandra
AU  - Vuković-Gačić, Branka
AU  - Javorac, Dragana
AU  - Antonijević Miljaković, Evica
AU  - Carević, Momir
AU  - Mandinić, Zoran
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10451
AB  - Excessive fluoride (F−) levels in the environment could induce different pathological changes, including comorbidities in reproductive functions. Hence, the aim of the present in vivo study was to explore F− subacute toxicity mechanisms via Benchmark dose (BMD) methodology on rat's testicles. The experiment was conducted on thirty male Wistar rats for 28 days, divided into six groups (n = 5): 1) Control (tap water); 2) 10 mg/L F−; 3) 25 mg/L F−; 4) 50 mg/L F−; 5) 100 mg/L F−; 6) 150 mg/L F−. Testicles were dissected out and processed for the determination of F− tissue concentrations, redox status parameters, essential elements level, and DNA damage. PROASTweb 70.1 software was used for determination of external and internal dose-response relationship. The results confirmed a significant increase in superoxide anion (O2.-), total oxidative status (TOS), copper (Cu), zinc (Zn), iron (Fe), DNA damage levels, and decrease in superoxide dismutase activity (SOD1) and total thiol (SH) groups. The dose-dependent changes were confirmed for SOD1 activity and DNA damage. The most sensitive parameters were SOD1 activity and DNA damage with the lowest BMDLs 0.1 μg F−/kg b. w. Since human and animal populations are daily and frequently unconsciously exposed to F−, this dose-response study is valuable for further research regarding the F− health risk assessment.
T2  - Environmental Pollution
T1  - Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage
VL  - 314
SP  - 120321
DO  - 10.1016/j.envpol.2022.120321
ER  - 
@article{
author = "Radovanović, Jelena and Antonijević, Biljana and Ćurčić, Marijana and Baralić, Katarina and Kolarević, Stoimir and Bulat, Zorica and Đukić-Ćosić, Danijela and Buha-Đorđević, Aleksandra and Vuković-Gačić, Branka and Javorac, Dragana and Antonijević Miljaković, Evica and Carević, Momir and Mandinić, Zoran",
year = "2022",
abstract = "Excessive fluoride (F−) levels in the environment could induce different pathological changes, including comorbidities in reproductive functions. Hence, the aim of the present in vivo study was to explore F− subacute toxicity mechanisms via Benchmark dose (BMD) methodology on rat's testicles. The experiment was conducted on thirty male Wistar rats for 28 days, divided into six groups (n = 5): 1) Control (tap water); 2) 10 mg/L F−; 3) 25 mg/L F−; 4) 50 mg/L F−; 5) 100 mg/L F−; 6) 150 mg/L F−. Testicles were dissected out and processed for the determination of F− tissue concentrations, redox status parameters, essential elements level, and DNA damage. PROASTweb 70.1 software was used for determination of external and internal dose-response relationship. The results confirmed a significant increase in superoxide anion (O2.-), total oxidative status (TOS), copper (Cu), zinc (Zn), iron (Fe), DNA damage levels, and decrease in superoxide dismutase activity (SOD1) and total thiol (SH) groups. The dose-dependent changes were confirmed for SOD1 activity and DNA damage. The most sensitive parameters were SOD1 activity and DNA damage with the lowest BMDLs 0.1 μg F−/kg b. w. Since human and animal populations are daily and frequently unconsciously exposed to F−, this dose-response study is valuable for further research regarding the F− health risk assessment.",
journal = "Environmental Pollution",
title = "Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage",
volume = "314",
pages = "120321",
doi = "10.1016/j.envpol.2022.120321"
}
Radovanović, J., Antonijević, B., Ćurčić, M., Baralić, K., Kolarević, S., Bulat, Z., Đukić-Ćosić, D., Buha-Đorđević, A., Vuković-Gačić, B., Javorac, D., Antonijević Miljaković, E., Carević, M.,& Mandinić, Z.. (2022). Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage. in Environmental Pollution, 314, 120321.
https://doi.org/10.1016/j.envpol.2022.120321
Radovanović J, Antonijević B, Ćurčić M, Baralić K, Kolarević S, Bulat Z, Đukić-Ćosić D, Buha-Đorđević A, Vuković-Gačić B, Javorac D, Antonijević Miljaković E, Carević M, Mandinić Z. Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage. in Environmental Pollution. 2022;314:120321.
doi:10.1016/j.envpol.2022.120321 .
Radovanović, Jelena, Antonijević, Biljana, Ćurčić, Marijana, Baralić, Katarina, Kolarević, Stoimir, Bulat, Zorica, Đukić-Ćosić, Danijela, Buha-Đorđević, Aleksandra, Vuković-Gačić, Branka, Javorac, Dragana, Antonijević Miljaković, Evica, Carević, Momir, Mandinić, Zoran, "Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage" in Environmental Pollution, 314 (2022):120321,
https://doi.org/10.1016/j.envpol.2022.120321 . .

Bend-free multiarm interferometers on optical chips

Petrović, Jovana; Maluckov, Aleksandra; Stojanović, Nikola

(2022)

TY  - JOUR
AU  - Petrović, Jovana
AU  - Maluckov, Aleksandra
AU  - Stojanović, Nikola
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10462
AB  - Multiarm interferometers can enhance measurement precision and provide multiparameter capability to the measurement. Their realisation requires multiport beam splitters, which has been a long-standing challenge in free-space and integrated optics. Here, we propose a new type of multiport interferometers suitable for implementation on optical chips. Their prospective advantages over the standard directional-coupler architectures: an arbitrary number of arms, planar architecture and two orders of magnitude reduction in footprint, are achieved by the layout based exclusively on the finite modulated photonic lattices. The inverse design of photonic lattices is facilitated by restricting the light propagation to periodic patterns. The corresponding interferometer model predicts the maximum $$1/\sqrt{N}$$sensitivity scaling with the number of arms N. While the presented design solutions are ubiquitous to all implementations, the advantages are discussed in both the low and high refractive-index contrast platforms. Finally, we provide an outlook on the possibilities for the interferometer applications in distributed classical and quantum measurements.
T2  - Optical and Quantum Electronics
T1  - Bend-free multiarm interferometers on optical chips
VL  - 54
IS  - 11
SP  - 687
DO  - 10.1007/s11082-022-04048-1
ER  - 
@article{
author = "Petrović, Jovana and Maluckov, Aleksandra and Stojanović, Nikola",
year = "2022",
abstract = "Multiarm interferometers can enhance measurement precision and provide multiparameter capability to the measurement. Their realisation requires multiport beam splitters, which has been a long-standing challenge in free-space and integrated optics. Here, we propose a new type of multiport interferometers suitable for implementation on optical chips. Their prospective advantages over the standard directional-coupler architectures: an arbitrary number of arms, planar architecture and two orders of magnitude reduction in footprint, are achieved by the layout based exclusively on the finite modulated photonic lattices. The inverse design of photonic lattices is facilitated by restricting the light propagation to periodic patterns. The corresponding interferometer model predicts the maximum $$1/\sqrt{N}$$sensitivity scaling with the number of arms N. While the presented design solutions are ubiquitous to all implementations, the advantages are discussed in both the low and high refractive-index contrast platforms. Finally, we provide an outlook on the possibilities for the interferometer applications in distributed classical and quantum measurements.",
journal = "Optical and Quantum Electronics",
title = "Bend-free multiarm interferometers on optical chips",
volume = "54",
number = "11",
pages = "687",
doi = "10.1007/s11082-022-04048-1"
}
Petrović, J., Maluckov, A.,& Stojanović, N.. (2022). Bend-free multiarm interferometers on optical chips. in Optical and Quantum Electronics, 54(11), 687.
https://doi.org/10.1007/s11082-022-04048-1
Petrović J, Maluckov A, Stojanović N. Bend-free multiarm interferometers on optical chips. in Optical and Quantum Electronics. 2022;54(11):687.
doi:10.1007/s11082-022-04048-1 .
Petrović, Jovana, Maluckov, Aleksandra, Stojanović, Nikola, "Bend-free multiarm interferometers on optical chips" in Optical and Quantum Electronics, 54, no. 11 (2022):687,
https://doi.org/10.1007/s11082-022-04048-1 . .

Development of modified pyrophyllite carbon paste electrode for carbendazim detection

Mitrović Rajić, Anđela I.; Milićević, Jelena S.; Grbović Novaković, Jasmina

(2022)

TY  - JOUR
AU  - Mitrović Rajić, Anđela I.
AU  - Milićević, Jelena S.
AU  - Grbović Novaković, Jasmina
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10472
AB  - This study aims to design the pyrophyllite-adapted carbon paste electrode (pCPE) and test it for potential use in wastewater purification systems. Structural characterization of pure pyrophyllite ore and mechanically modified pyrophyllite in mortar and pestle has been followed by XRD, SEM, PSA, and FTIR. Electrochemical characteristics were studied by cyclic voltammetry of pyrophyllite CPE in sulfuric acid and potassium ferrocyanide, as redox model compounds. Delamination, gliding, and folding of the layers and a decrease in particle and crystallite size have been observed, leading to the excellent electrocatalytic activity of pCPE. The developed pCPE has numerous benefits such as a simple preparation method, rapid response, and good sensitivity. The oxidation peak of carbendazim appears in Britton-Robinson buffer solutions (pH 4) at +0.9 V vs. Ag/AgCl. The developed method is linear in the concentration range of 3.2–29.2 ng cm−3, with r = 0.999 and the limit of detection of 1.9 ng cm−3.
T2  - Materials and Manufacturing Processes
T1  - Development of modified pyrophyllite carbon paste electrode for carbendazim detection
IS  - Inpress
SP  - 1
EP  - 7
DO  - 10.1080/10426914.2022.2136386
ER  - 
@article{
author = "Mitrović Rajić, Anđela I. and Milićević, Jelena S. and Grbović Novaković, Jasmina",
year = "2022",
abstract = "This study aims to design the pyrophyllite-adapted carbon paste electrode (pCPE) and test it for potential use in wastewater purification systems. Structural characterization of pure pyrophyllite ore and mechanically modified pyrophyllite in mortar and pestle has been followed by XRD, SEM, PSA, and FTIR. Electrochemical characteristics were studied by cyclic voltammetry of pyrophyllite CPE in sulfuric acid and potassium ferrocyanide, as redox model compounds. Delamination, gliding, and folding of the layers and a decrease in particle and crystallite size have been observed, leading to the excellent electrocatalytic activity of pCPE. The developed pCPE has numerous benefits such as a simple preparation method, rapid response, and good sensitivity. The oxidation peak of carbendazim appears in Britton-Robinson buffer solutions (pH 4) at +0.9 V vs. Ag/AgCl. The developed method is linear in the concentration range of 3.2–29.2 ng cm−3, with r = 0.999 and the limit of detection of 1.9 ng cm−3.",
journal = "Materials and Manufacturing Processes",
title = "Development of modified pyrophyllite carbon paste electrode for carbendazim detection",
number = "Inpress",
pages = "1-7",
doi = "10.1080/10426914.2022.2136386"
}
Mitrović Rajić, A. I., Milićević, J. S.,& Grbović Novaković, J.. (2022). Development of modified pyrophyllite carbon paste electrode for carbendazim detection. in Materials and Manufacturing Processes(Inpress), 1-7.
https://doi.org/10.1080/10426914.2022.2136386
Mitrović Rajić AI, Milićević JS, Grbović Novaković J. Development of modified pyrophyllite carbon paste electrode for carbendazim detection. in Materials and Manufacturing Processes. 2022;(Inpress):1-7.
doi:10.1080/10426914.2022.2136386 .
Mitrović Rajić, Anđela I., Milićević, Jelena S., Grbović Novaković, Jasmina, "Development of modified pyrophyllite carbon paste electrode for carbendazim detection" in Materials and Manufacturing Processes, no. Inpress (2022):1-7,
https://doi.org/10.1080/10426914.2022.2136386 . .

On the Geochemistry of the Danube River Sediments (Serbian Sector)

Culicov, Otilia Ana; Trtić-Petrović, Tatjana; Nekhoroshkov, Pavel S.; Zinicovscaia, Inga; Duliu, Octavian G.

(2022)

TY  - JOUR
AU  - Culicov, Otilia Ana
AU  - Trtić-Petrović, Tatjana
AU  - Nekhoroshkov, Pavel S.
AU  - Zinicovscaia, Inga
AU  - Duliu, Octavian G.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10463
AB  - To determine the nature and origin of the unconsolidated bottom sediments, as well as to demonstrate and quantify the presence of Presumably Contaminating Elements (PCE) in the Serbian Danube River, as a novelty, the mass fractions on nine major elements as oxides—SiO2, TiO2, Al2O3, FeO, MnO, MgO, CaO, Na2O, and K2O, as well as Sc, V, Cr, Co, Ni, Cu, Zn, As, Rb, Sr, Zr, Sb, Cs, Ba, La, Hf, Ta, W, Th, and U were determined by Instrumental Neutron Activation Analysis (INAA) in 13 sediment samples collected between Belgrade and Iron Gate 2 dam. INAA was chosen for its ability to perform elemental analysis without any preliminary sample treatment that could introduce systematic errors. The distribution of major elements was relatively uniform, with the sampling locations having less influence. Concerning the trace elements, excepting the PCE Cr, Ni, Cu, Zn, As, and Sb, their distributions presented the same remarkable similarity to the Upper Continental Crust (UCC), North American Shale Composite (NASC), Average Bottom Load (ABL), and Average Dobrogea Loess (AVL), and were in good concordance with the location of the Serbian Danube River in the Pannonian Plain. In the case of considered PCE, both Enrichment Factor and Pollution Load Index showed values higher than the pollution threshold, which pointed towards a significant anthropogenic contamination, and rising concern to what extent the water quality and biota could be affected.
T2  - International Journal of Environmental Research and Public Health
T1  - On the Geochemistry of the Danube River Sediments (Serbian Sector)
VL  - 19
IS  - 19
SP  - 12879
DO  - 10.3390/ijerph191912879
ER  - 
@article{
author = "Culicov, Otilia Ana and Trtić-Petrović, Tatjana and Nekhoroshkov, Pavel S. and Zinicovscaia, Inga and Duliu, Octavian G.",
year = "2022",
abstract = "To determine the nature and origin of the unconsolidated bottom sediments, as well as to demonstrate and quantify the presence of Presumably Contaminating Elements (PCE) in the Serbian Danube River, as a novelty, the mass fractions on nine major elements as oxides—SiO2, TiO2, Al2O3, FeO, MnO, MgO, CaO, Na2O, and K2O, as well as Sc, V, Cr, Co, Ni, Cu, Zn, As, Rb, Sr, Zr, Sb, Cs, Ba, La, Hf, Ta, W, Th, and U were determined by Instrumental Neutron Activation Analysis (INAA) in 13 sediment samples collected between Belgrade and Iron Gate 2 dam. INAA was chosen for its ability to perform elemental analysis without any preliminary sample treatment that could introduce systematic errors. The distribution of major elements was relatively uniform, with the sampling locations having less influence. Concerning the trace elements, excepting the PCE Cr, Ni, Cu, Zn, As, and Sb, their distributions presented the same remarkable similarity to the Upper Continental Crust (UCC), North American Shale Composite (NASC), Average Bottom Load (ABL), and Average Dobrogea Loess (AVL), and were in good concordance with the location of the Serbian Danube River in the Pannonian Plain. In the case of considered PCE, both Enrichment Factor and Pollution Load Index showed values higher than the pollution threshold, which pointed towards a significant anthropogenic contamination, and rising concern to what extent the water quality and biota could be affected.",
journal = "International Journal of Environmental Research and Public Health",
title = "On the Geochemistry of the Danube River Sediments (Serbian Sector)",
volume = "19",
number = "19",
pages = "12879",
doi = "10.3390/ijerph191912879"
}
Culicov, O. A., Trtić-Petrović, T., Nekhoroshkov, P. S., Zinicovscaia, I.,& Duliu, O. G.. (2022). On the Geochemistry of the Danube River Sediments (Serbian Sector). in International Journal of Environmental Research and Public Health, 19(19), 12879.
https://doi.org/10.3390/ijerph191912879
Culicov OA, Trtić-Petrović T, Nekhoroshkov PS, Zinicovscaia I, Duliu OG. On the Geochemistry of the Danube River Sediments (Serbian Sector). in International Journal of Environmental Research and Public Health. 2022;19(19):12879.
doi:10.3390/ijerph191912879 .
Culicov, Otilia Ana, Trtić-Petrović, Tatjana, Nekhoroshkov, Pavel S., Zinicovscaia, Inga, Duliu, Octavian G., "On the Geochemistry of the Danube River Sediments (Serbian Sector)" in International Journal of Environmental Research and Public Health, 19, no. 19 (2022):12879,
https://doi.org/10.3390/ijerph191912879 . .

The high-dose fish oil supplementation increased Mfsd2a expression without altering DHA levels in the retina of healthy mice

Jovanović Macura, Irena; Đuričić, Ivana; Major, Tamara; Milanović, Desanka; Brkić, Marjana; Šobajić, Slađana; Kanazir, Selma; Ivković, Sanja

(2022)

TY  - JOUR
AU  - Jovanović Macura, Irena
AU  - Đuričić, Ivana
AU  - Major, Tamara
AU  - Milanović, Desanka
AU  - Brkić, Marjana
AU  - Šobajić, Slađana
AU  - Kanazir, Selma
AU  - Ivković, Sanja
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10478
AB  - The recommended fish oil (FO) supplementation doses often yield low omega-3 polyunsaturated fatty acids (PUFAs) tissue bioavailability, and higher doses (up to 10 g per day) have been increasingly recommended. However, the exact effects of such FO supplementation on the healthy retina and retinal pigmented epithelium (RPE) are unknown. Our study showed that the high dose FO treatment did not imbalance the rigorous docosahexaenoic acid (DHA, C22:6n3) homeostasis in the retina and RPE in the three-month-old female B6/SLJ mice. Instead, we have found the significant increase in the expression of Mfsd2a, the main DHA transporter. Mfsd2a is also an essential regulator of blood vessel transcytosis and the decrease in Mfsd2a expression can be a risk factor for developing leaky blood vessels. Therefore, the high-dose FO supplementation emerges as the prophylactic fortifier of the retinal blood vessels.
T2  - Journal of Functional Foods
T1  - The high-dose fish oil supplementation increased Mfsd2a expression without altering DHA levels in the retina of healthy mice
VL  - 99
SP  - 105302
DO  - 10.1016/j.jff.2022.105302
ER  - 
@article{
author = "Jovanović Macura, Irena and Đuričić, Ivana and Major, Tamara and Milanović, Desanka and Brkić, Marjana and Šobajić, Slađana and Kanazir, Selma and Ivković, Sanja",
year = "2022",
abstract = "The recommended fish oil (FO) supplementation doses often yield low omega-3 polyunsaturated fatty acids (PUFAs) tissue bioavailability, and higher doses (up to 10 g per day) have been increasingly recommended. However, the exact effects of such FO supplementation on the healthy retina and retinal pigmented epithelium (RPE) are unknown. Our study showed that the high dose FO treatment did not imbalance the rigorous docosahexaenoic acid (DHA, C22:6n3) homeostasis in the retina and RPE in the three-month-old female B6/SLJ mice. Instead, we have found the significant increase in the expression of Mfsd2a, the main DHA transporter. Mfsd2a is also an essential regulator of blood vessel transcytosis and the decrease in Mfsd2a expression can be a risk factor for developing leaky blood vessels. Therefore, the high-dose FO supplementation emerges as the prophylactic fortifier of the retinal blood vessels.",
journal = "Journal of Functional Foods",
title = "The high-dose fish oil supplementation increased Mfsd2a expression without altering DHA levels in the retina of healthy mice",
volume = "99",
pages = "105302",
doi = "10.1016/j.jff.2022.105302"
}
Jovanović Macura, I., Đuričić, I., Major, T., Milanović, D., Brkić, M., Šobajić, S., Kanazir, S.,& Ivković, S.. (2022). The high-dose fish oil supplementation increased Mfsd2a expression without altering DHA levels in the retina of healthy mice. in Journal of Functional Foods, 99, 105302.
https://doi.org/10.1016/j.jff.2022.105302
Jovanović Macura I, Đuričić I, Major T, Milanović D, Brkić M, Šobajić S, Kanazir S, Ivković S. The high-dose fish oil supplementation increased Mfsd2a expression without altering DHA levels in the retina of healthy mice. in Journal of Functional Foods. 2022;99:105302.
doi:10.1016/j.jff.2022.105302 .
Jovanović Macura, Irena, Đuričić, Ivana, Major, Tamara, Milanović, Desanka, Brkić, Marjana, Šobajić, Slađana, Kanazir, Selma, Ivković, Sanja, "The high-dose fish oil supplementation increased Mfsd2a expression without altering DHA levels in the retina of healthy mice" in Journal of Functional Foods, 99 (2022):105302,
https://doi.org/10.1016/j.jff.2022.105302 . .