Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200129 (University of Belgrade, Faculty of Dental Medicine)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200129 (University of Belgrade, Faculty of Dental Medicine) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200129 (Univerzitet u Beogradu, Stomatološki fakultet) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200129 (Универзитет у Београду, Стоматолошки факултет) (sr)
Authors

Publications

Analiza fraktalne prirode specifične aktivnosti berilijuma-7 u prizemnom sloju atmosfere merene u Beogradu, Srbija (1991-2022)

Sarvan, Darko; Stratimirović, Đorđe; Rajačić, Milica; Krneta Nikolić, Jelena; Vukanac, Ivana; Ajtić, Jelena

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Sarvan, Darko
AU  - Stratimirović, Đorđe
AU  - Rajačić, Milica
AU  - Krneta Nikolić, Jelena
AU  - Vukanac, Ivana
AU  - Ajtić, Jelena
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12173
AB  - U ovom istraživanju analizirana je fraktalna priroda vremenske serije specifične aktivnosti berilijuma-7 u površinskom sloju atmosfere u Beogradu, Srbija, sa ciljem da se prouči dinamika njene samosličnosti, a s posebnim fokusom na godišnji ciklus. Korišćene su metode vejvlet analize i vremenski zavisne detrendovane pokretne srednje vrednosti radi identifikacije karakterističnih intervala i procene Hurstovih eksponenata. Podaci o specifičnoj aktivnosti berilijuma-7 preuzeti su iz GRAMON baze podataka, za lokaciju Beograd (44,88 °N; 20,58 °E; 95 m nadmorske visine). Vremenska serija obuhvata 362 mesečna merenja od 1991. do 2022. godine. Rezultati ukazuju na postojanje izraženog godišnjeg ciklusa u ovoj vremenskoj seriji. Takođe, promene u lokalnom Hurstovom eksponentu otkrivaju varijacije u ponašanju vremenske serije – ona iz umereno korelisanog prelazi u izrazito antikorelisan proces između 2015. i 2020. godine. Ovaj rezultat biće predmet šire analize koja uključuje i druge lokacije iz GRAMON baze podataka.
AB  - This research analyzes the fractal nature of the beryllium-7 specific activity time series in the near-surface layer of the atmosphere in Belgrade, Serbia. The aim was to study the dynamics of self-similarity in this series, with a particular focus on the annual cycle. Wavelet analysis and time-dependent detrended moving averages were used to identify characteristic intervals and estimate Hurst exponents. The data on specific activity of beryllium-7 were obtained from the GRAMON database for the location of Belgrade (44.88 °N; 20.58 °E; 95 m a.s.l.). The time series comprises 362 monthly measurements between February 1991 and December 2022. The results indicate a pronounced annual cycle in this time series. Moreover, changes in the local Hurst exponent reveal variations in the behavior of the time series, transitioning from moderately correlated to highly anti-correlated process between 2015. and 2020. This finding will be a subject of a further analysis including other locations from the GRAMON database.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Analiza fraktalne prirode specifične aktivnosti berilijuma-7 u prizemnom sloju atmosfere merene u Beogradu, Srbija (1991-2022)
T1  - Analysis of the Fractal Nature of the Specific Activity of Beryllium-7 in the Near-Surface Layer of the Atmosphere Measured in Belgrade, Serbia (1991–2022)
SP  - 122
EP  - 127
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12173
ER  - 
@conference{
author = "Sarvan, Darko and Stratimirović, Đorđe and Rajačić, Milica and Krneta Nikolić, Jelena and Vukanac, Ivana and Ajtić, Jelena",
year = "2023",
abstract = "U ovom istraživanju analizirana je fraktalna priroda vremenske serije specifične aktivnosti berilijuma-7 u površinskom sloju atmosfere u Beogradu, Srbija, sa ciljem da se prouči dinamika njene samosličnosti, a s posebnim fokusom na godišnji ciklus. Korišćene su metode vejvlet analize i vremenski zavisne detrendovane pokretne srednje vrednosti radi identifikacije karakterističnih intervala i procene Hurstovih eksponenata. Podaci o specifičnoj aktivnosti berilijuma-7 preuzeti su iz GRAMON baze podataka, za lokaciju Beograd (44,88 °N; 20,58 °E; 95 m nadmorske visine). Vremenska serija obuhvata 362 mesečna merenja od 1991. do 2022. godine. Rezultati ukazuju na postojanje izraženog godišnjeg ciklusa u ovoj vremenskoj seriji. Takođe, promene u lokalnom Hurstovom eksponentu otkrivaju varijacije u ponašanju vremenske serije – ona iz umereno korelisanog prelazi u izrazito antikorelisan proces između 2015. i 2020. godine. Ovaj rezultat biće predmet šire analize koja uključuje i druge lokacije iz GRAMON baze podataka., This research analyzes the fractal nature of the beryllium-7 specific activity time series in the near-surface layer of the atmosphere in Belgrade, Serbia. The aim was to study the dynamics of self-similarity in this series, with a particular focus on the annual cycle. Wavelet analysis and time-dependent detrended moving averages were used to identify characteristic intervals and estimate Hurst exponents. The data on specific activity of beryllium-7 were obtained from the GRAMON database for the location of Belgrade (44.88 °N; 20.58 °E; 95 m a.s.l.). The time series comprises 362 monthly measurements between February 1991 and December 2022. The results indicate a pronounced annual cycle in this time series. Moreover, changes in the local Hurst exponent reveal variations in the behavior of the time series, transitioning from moderately correlated to highly anti-correlated process between 2015. and 2020. This finding will be a subject of a further analysis including other locations from the GRAMON database.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Analiza fraktalne prirode specifične aktivnosti berilijuma-7 u prizemnom sloju atmosfere merene u Beogradu, Srbija (1991-2022), Analysis of the Fractal Nature of the Specific Activity of Beryllium-7 in the Near-Surface Layer of the Atmosphere Measured in Belgrade, Serbia (1991–2022)",
pages = "122-127",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12173"
}
Sarvan, D., Stratimirović, Đ., Rajačić, M., Krneta Nikolić, J., Vukanac, I.,& Ajtić, J.. (2023). Analiza fraktalne prirode specifične aktivnosti berilijuma-7 u prizemnom sloju atmosfere merene u Beogradu, Srbija (1991-2022). in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 122-127.
https://hdl.handle.net/21.15107/rcub_vinar_12173
Sarvan D, Stratimirović Đ, Rajačić M, Krneta Nikolić J, Vukanac I, Ajtić J. Analiza fraktalne prirode specifične aktivnosti berilijuma-7 u prizemnom sloju atmosfere merene u Beogradu, Srbija (1991-2022). in 32. simpozijum DZZSCG : zbornik radova. 2023;:122-127.
https://hdl.handle.net/21.15107/rcub_vinar_12173 .
Sarvan, Darko, Stratimirović, Đorđe, Rajačić, Milica, Krneta Nikolić, Jelena, Vukanac, Ivana, Ajtić, Jelena, "Analiza fraktalne prirode specifične aktivnosti berilijuma-7 u prizemnom sloju atmosfere merene u Beogradu, Srbija (1991-2022)" in 32. simpozijum DZZSCG : zbornik radova (2023):122-127,
https://hdl.handle.net/21.15107/rcub_vinar_12173 .

Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings

Barać, Milena; Petrović, Milan; Petrović, Nina; Nikolić-Jakoba, Nataša; Aleksić, Zoran; Todorović, Lidija; Petrović-Stanojević, Nataša; Anđelić-Jelić, Marina; Davidović, Aleksandar; Milašin, Jelena; Roganović, Jelena

(2023)

TY  - JOUR
AU  - Barać, Milena
AU  - Petrović, Milan
AU  - Petrović, Nina
AU  - Nikolić-Jakoba, Nataša
AU  - Aleksić, Zoran
AU  - Todorović, Lidija
AU  - Petrović-Stanojević, Nataša
AU  - Anđelić-Jelić, Marina
AU  - Davidović, Aleksandar
AU  - Milašin, Jelena
AU  - Roganović, Jelena
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11499
AB  - Type 2 diabetes mellitus (T2DM) is associated with functional deterioration of the salivary gland and dental pulp, related to oxidative stress. The aim was to integrate experimental and bioinformatic findings to analyze the cellular mechanism of melatonin (MEL) action in the human parotid gland and dental pulp in diabetes. Human parotid gland tissue was obtained from 16 non-diabetic and 16 diabetic participants, as well as human dental pulp from 15 non-diabetic and 15 diabetic participants. In human non-diabetic and diabetic parotid gland cells (hPGCs) as well as in dental pulp cells (hDPCs), cultured in hyper- and normoglycemic conditions, glial cell linederived neurotrophic factor (GDNF), MEL, inducible nitric oxide synthase (iNOS) protein expression, and superoxide dismutase (SOD) activity were measured by enzyme-linked immunosorbent assay (ELISA) and spectrophotometrically. Bioinformatic analysis was performed using ShinyGO (v.0.75) application. Diabetic participants had increased GDNF and decreased MEL in parotid (p < 0.01) and dental pulp (p < 0.05) tissues, associated with increased iNOS and SOD activity. Normoglycemic hDPCs and non-diabetic hPGCs treated with 0.1 mM MEL had increased GDNF (p < 0.05), while hyperglycemic hDPCs treated with 1 mM MEL showed a decrease in up-regulated GDNF (p < 0.05). Enrichment analyses showed interference with stress and ATF/CREB signaling. MEL induced the stress-protective mechanism in hyperglycemic hDPCs and diabetic hPGCs, suggesting MEL could be beneficial for diabetes-associated disturbances in oral tissues.
T2  - International Journal of Environmental Research and Public Health
T1  - Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings
VL  - 20
IS  - 18
SP  - 6727
DO  - 10.3390/ijerph20186727
ER  - 
@article{
author = "Barać, Milena and Petrović, Milan and Petrović, Nina and Nikolić-Jakoba, Nataša and Aleksić, Zoran and Todorović, Lidija and Petrović-Stanojević, Nataša and Anđelić-Jelić, Marina and Davidović, Aleksandar and Milašin, Jelena and Roganović, Jelena",
year = "2023",
abstract = "Type 2 diabetes mellitus (T2DM) is associated with functional deterioration of the salivary gland and dental pulp, related to oxidative stress. The aim was to integrate experimental and bioinformatic findings to analyze the cellular mechanism of melatonin (MEL) action in the human parotid gland and dental pulp in diabetes. Human parotid gland tissue was obtained from 16 non-diabetic and 16 diabetic participants, as well as human dental pulp from 15 non-diabetic and 15 diabetic participants. In human non-diabetic and diabetic parotid gland cells (hPGCs) as well as in dental pulp cells (hDPCs), cultured in hyper- and normoglycemic conditions, glial cell linederived neurotrophic factor (GDNF), MEL, inducible nitric oxide synthase (iNOS) protein expression, and superoxide dismutase (SOD) activity were measured by enzyme-linked immunosorbent assay (ELISA) and spectrophotometrically. Bioinformatic analysis was performed using ShinyGO (v.0.75) application. Diabetic participants had increased GDNF and decreased MEL in parotid (p < 0.01) and dental pulp (p < 0.05) tissues, associated with increased iNOS and SOD activity. Normoglycemic hDPCs and non-diabetic hPGCs treated with 0.1 mM MEL had increased GDNF (p < 0.05), while hyperglycemic hDPCs treated with 1 mM MEL showed a decrease in up-regulated GDNF (p < 0.05). Enrichment analyses showed interference with stress and ATF/CREB signaling. MEL induced the stress-protective mechanism in hyperglycemic hDPCs and diabetic hPGCs, suggesting MEL could be beneficial for diabetes-associated disturbances in oral tissues.",
journal = "International Journal of Environmental Research and Public Health",
title = "Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings",
volume = "20",
number = "18",
pages = "6727",
doi = "10.3390/ijerph20186727"
}
Barać, M., Petrović, M., Petrović, N., Nikolić-Jakoba, N., Aleksić, Z., Todorović, L., Petrović-Stanojević, N., Anđelić-Jelić, M., Davidović, A., Milašin, J.,& Roganović, J.. (2023). Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings. in International Journal of Environmental Research and Public Health, 20(18), 6727.
https://doi.org/10.3390/ijerph20186727
Barać M, Petrović M, Petrović N, Nikolić-Jakoba N, Aleksić Z, Todorović L, Petrović-Stanojević N, Anđelić-Jelić M, Davidović A, Milašin J, Roganović J. Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings. in International Journal of Environmental Research and Public Health. 2023;20(18):6727.
doi:10.3390/ijerph20186727 .
Barać, Milena, Petrović, Milan, Petrović, Nina, Nikolić-Jakoba, Nataša, Aleksić, Zoran, Todorović, Lidija, Petrović-Stanojević, Nataša, Anđelić-Jelić, Marina, Davidović, Aleksandar, Milašin, Jelena, Roganović, Jelena, "Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings" in International Journal of Environmental Research and Public Health, 20, no. 18 (2023):6727,
https://doi.org/10.3390/ijerph20186727 . .

Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review

Roganović, Jelena; Petrović, Nina

(2022)

TY  - JOUR
AU  - Roganović, Jelena
AU  - Petrović, Nina
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10401
AB  - Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions and due to their involvement in different diseases, including oral inflammatory diseases. Based on ncRNAs’ suitability for salivary biomarkers and their involvement in neuropathic pain and tissue regeneration signaling pathways, the present narrative review aims to highlight the potential clinical applications of ncRNAs in oral inflammatory diseases, with an emphasis on salivary diagnostics, regenerative dentistry, and precision medicine for neuropathic orofacial pain.
T2  - International Journal of Molecular Sciences
T1  - Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review
VL  - 23
IS  - 15
SP  - 8278
DO  - 10.3390/ijms23158278
ER  - 
@article{
author = "Roganović, Jelena and Petrović, Nina",
year = "2022",
abstract = "Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions and due to their involvement in different diseases, including oral inflammatory diseases. Based on ncRNAs’ suitability for salivary biomarkers and their involvement in neuropathic pain and tissue regeneration signaling pathways, the present narrative review aims to highlight the potential clinical applications of ncRNAs in oral inflammatory diseases, with an emphasis on salivary diagnostics, regenerative dentistry, and precision medicine for neuropathic orofacial pain.",
journal = "International Journal of Molecular Sciences",
title = "Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review",
volume = "23",
number = "15",
pages = "8278",
doi = "10.3390/ijms23158278"
}
Roganović, J.,& Petrović, N.. (2022). Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review. in International Journal of Molecular Sciences, 23(15), 8278.
https://doi.org/10.3390/ijms23158278
Roganović J, Petrović N. Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review. in International Journal of Molecular Sciences. 2022;23(15):8278.
doi:10.3390/ijms23158278 .
Roganović, Jelena, Petrović, Nina, "Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review" in International Journal of Molecular Sciences, 23, no. 15 (2022):8278,
https://doi.org/10.3390/ijms23158278 . .
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Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes

Matić, Tamara; Zebić, M. Ležaja; Miletić, Vesna; Cvijović-Alagić, Ivana; Petrović, Rada D.; Janaćković, Đorđe T.; Veljović, Đorđe N.

(2022)

TY  - JOUR
AU  - Matić, Tamara
AU  - Zebić, M. Ležaja
AU  - Miletić, Vesna
AU  - Cvijović-Alagić, Ivana
AU  - Petrović, Rada D.
AU  - Janaćković, Đorđe T.
AU  - Veljović, Đorđe N.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10114
AB  - The aim of this study was to investigate the influence of binary Sr, Mg ion-doping compared to the single-ion doping effects on the phase composition and morphology of hydrothermally obtained calcium hydroxyapatite (HAP) powders and on the phase composition, microstructure, and mechanical properties of the sintered materials. Additionally, the focus of this study was to investigate the possible utilization of the binary doped Sr,Mg-HAP compacts as dentin substitutes in restorative dentistry by evaluating their bonding ability with commercially available restorative materials using the shear bond strength test (SBS). The hydrothermally obtained mono-doped Mg5 and Sr5 showed the monophasic apatite structure, while in all co-doped samples β-TCP phase was formed, resulting in biphasic calcium phosphate (BCP) powders. It was confirmed that co-doping with Sr and Mg ions led to the thermal stabilization of the β-TCP phase by suppressing the phase transition into α-TCP when sintered at 1200 °C. Moreover, the co-presence of Mg ions significantly improved the hardness of Sr-doped HAP from 3.74 to 5.02 GPa. Sr,Mg-HAP dental inserts were found to achieve sufficient bonding (13.53 MPa) through the micromechanical interlocking with Z250 dental composite and Single Bond Universal dental adhesive applied with a total etch approach. The SBS values obtained for the SrMg-HAP insert were similar to the literature data on bonding ability with human dentin, indicating that binary doped Sr,Mg-HAP ceramics present a promising material for application in restorative dentistry as dentin substitutes.
T2  - Ceramics International
T1  - Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes
DO  - 10.1016/j.ceramint.2021.12.335
ER  - 
@article{
author = "Matić, Tamara and Zebić, M. Ležaja and Miletić, Vesna and Cvijović-Alagić, Ivana and Petrović, Rada D. and Janaćković, Đorđe T. and Veljović, Đorđe N.",
year = "2022",
abstract = "The aim of this study was to investigate the influence of binary Sr, Mg ion-doping compared to the single-ion doping effects on the phase composition and morphology of hydrothermally obtained calcium hydroxyapatite (HAP) powders and on the phase composition, microstructure, and mechanical properties of the sintered materials. Additionally, the focus of this study was to investigate the possible utilization of the binary doped Sr,Mg-HAP compacts as dentin substitutes in restorative dentistry by evaluating their bonding ability with commercially available restorative materials using the shear bond strength test (SBS). The hydrothermally obtained mono-doped Mg5 and Sr5 showed the monophasic apatite structure, while in all co-doped samples β-TCP phase was formed, resulting in biphasic calcium phosphate (BCP) powders. It was confirmed that co-doping with Sr and Mg ions led to the thermal stabilization of the β-TCP phase by suppressing the phase transition into α-TCP when sintered at 1200 °C. Moreover, the co-presence of Mg ions significantly improved the hardness of Sr-doped HAP from 3.74 to 5.02 GPa. Sr,Mg-HAP dental inserts were found to achieve sufficient bonding (13.53 MPa) through the micromechanical interlocking with Z250 dental composite and Single Bond Universal dental adhesive applied with a total etch approach. The SBS values obtained for the SrMg-HAP insert were similar to the literature data on bonding ability with human dentin, indicating that binary doped Sr,Mg-HAP ceramics present a promising material for application in restorative dentistry as dentin substitutes.",
journal = "Ceramics International",
title = "Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes",
doi = "10.1016/j.ceramint.2021.12.335"
}
Matić, T., Zebić, M. L., Miletić, V., Cvijović-Alagić, I., Petrović, R. D., Janaćković, Đ. T.,& Veljović, Đ. N.. (2022). Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes. in Ceramics International.
https://doi.org/10.1016/j.ceramint.2021.12.335
Matić T, Zebić ML, Miletić V, Cvijović-Alagić I, Petrović RD, Janaćković ĐT, Veljović ĐN. Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes. in Ceramics International. 2022;.
doi:10.1016/j.ceramint.2021.12.335 .
Matić, Tamara, Zebić, M. Ležaja, Miletić, Vesna, Cvijović-Alagić, Ivana, Petrović, Rada D., Janaćković, Đorđe T., Veljović, Đorđe N., "Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes" in Ceramics International (2022),
https://doi.org/10.1016/j.ceramint.2021.12.335 . .
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