TY  - JOUR
AU  - Kolarski, Milenko
AU  - Joksić, Gordana
AU  - Beres, Maja
AU  - Krstić, Aleksandar
AU  - Joksić, Ivana
AU  - Dobrojevic, Boris
AU  - Nikic, Slavko
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3625
AB  - We report the first case of Pallister-Killian syndrome diagnosed prenatally in Western Balkan region where one of the ultrasound markers was intrauterine growth restriction. During routine ultrasound control of the pregnancy at 21st gestation week (second pregnancy of the 25 year old woman) symmetrical intrauterine growth restriction (IUGR), short long bones, ventriculomegaly and oligoamnion were noted. Amniotic fluid was examined cytogenetically. Fetal karyotype obtained by GTG banding of amniocytes revealed mosaic female karyotype 46,XX/47,XX,+mar (F-like). C-banding indicated that F-like marker does not belong to F, E or G chromosomal group. Employing targeted FISH with arm-specific probe for chromosome 12, tetrasomy 12p was confirmed. Fetal lymphocytes revealed normal female karyotype. This case showed that i(12p) could be found in pregnancy of young woman, not only in those of advanced age, as usually reported in the literature. This case also showed that intrauterine growth restriction could be one of the ultrasound markers associated with Pallister-Killian syndrome.
T2  - Archives of Gynecology and Obstetrics
T1  - Prenatal diagnosis of Pallister-Killian syndrome in young woman: ultrasound indicators and confirmation by FISH
VL  - 279
IS  - 3
SP  - 377
EP  - 379
DO  - 10.1007/s00404-008-0704-6
ER  - 

@article{
author = "Kolarski, Milenko and Joksić, Gordana and Beres, Maja and Krstić, Aleksandar and Joksić, Ivana and Dobrojevic, Boris and Nikic, Slavko",
year = "2009",
abstract = "We report the first case of Pallister-Killian syndrome diagnosed prenatally in Western Balkan region where one of the ultrasound markers was intrauterine growth restriction. During routine ultrasound control of the pregnancy at 21st gestation week (second pregnancy of the 25 year old woman) symmetrical intrauterine growth restriction (IUGR), short long bones, ventriculomegaly and oligoamnion were noted. Amniotic fluid was examined cytogenetically. Fetal karyotype obtained by GTG banding of amniocytes revealed mosaic female karyotype 46,XX/47,XX,+mar (F-like). C-banding indicated that F-like marker does not belong to F, E or G chromosomal group. Employing targeted FISH with arm-specific probe for chromosome 12, tetrasomy 12p was confirmed. Fetal lymphocytes revealed normal female karyotype. This case showed that i(12p) could be found in pregnancy of young woman, not only in those of advanced age, as usually reported in the literature. This case also showed that intrauterine growth restriction could be one of the ultrasound markers associated with Pallister-Killian syndrome.",
journal = "Archives of Gynecology and Obstetrics",
title = "Prenatal diagnosis of Pallister-Killian syndrome in young woman: ultrasound indicators and confirmation by FISH",
volume = "279",
number = "3",
pages = "377-379",
doi = "10.1007/s00404-008-0704-6"
}

Kolarski, M., Joksić, G., Beres, M., Krstić, A., Joksić, I., Dobrojevic, B.,& Nikic, S.. (2009). Prenatal diagnosis of Pallister-Killian syndrome in young woman: ultrasound indicators and confirmation by FISH. in Archives of Gynecology and Obstetrics, 279(3), 377-379.
https://doi.org/10.1007/s00404-008-0704-6

Kolarski M, Joksić G, Beres M, Krstić A, Joksić I, Dobrojevic B, Nikic S. Prenatal diagnosis of Pallister-Killian syndrome in young woman: ultrasound indicators and confirmation by FISH. in Archives of Gynecology and Obstetrics. 2009;279(3):377-379.
doi:10.1007/s00404-008-0704-6 .

Kolarski, Milenko, Joksić, Gordana, Beres, Maja, Krstić, Aleksandar, Joksić, Ivana, Dobrojevic, Boris, Nikic, Slavko, "Prenatal diagnosis of Pallister-Killian syndrome in young woman: ultrasound indicators and confirmation by FISH" in Archives of Gynecology and Obstetrics, 279, no. 3 (2009):377-379,
https://doi.org/10.1007/s00404-008-0704-6 . .

TY  - JOUR
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Joksić, Gordana
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3567
AB  - The radioprotective properties of polyphenols from the plant Gentiana dinarica Beck. (family Gentianaceae) were evaluated in cultured human peripheral blood lymphocytes exposed to 2 Gy of gamma radiation in vitro. Major constituents of G. dinarica roots include tetraoxygenated xanthones (gentiacaulein and gentiakochianin), tetraoxygenated xanthone glycosides (norswertianin- 1-O-primveroside and norswertianin-8-O-primveroside), C-glucoflavones (isoorientin and isoorientin- 4-O-glycoside) and secoridoids. The incidences of micronuclei, cell proliferation, apoptosis and lipid peroxidation products were examined. Isoorientin, isoorientin- 4-O-glycoside and norswertianin-1-O-primveroside showed antioxidant properties, whereas norswertianin-8-O-primveroside and gentiacaulein exhibited pro-oxidative effects. Gentiakochianin exhibited cytostatic effects in irradiated lymphocytes. These results contribute to the search for novel radioprotective agents.
T2  - Current Science
T1  - Radioprotective properties of Gentiana dinarica polyphenols on human lymphocytes in vitro
VL  - 95
IS  - 8
SP  - 1035
EP  - 1041
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3567
ER  - 

@article{
author = "Petrović, Sandra and Leskovac, Andreja and Joksić, Gordana",
year = "2008",
abstract = "The radioprotective properties of polyphenols from the plant Gentiana dinarica Beck. (family Gentianaceae) were evaluated in cultured human peripheral blood lymphocytes exposed to 2 Gy of gamma radiation in vitro. Major constituents of G. dinarica roots include tetraoxygenated xanthones (gentiacaulein and gentiakochianin), tetraoxygenated xanthone glycosides (norswertianin- 1-O-primveroside and norswertianin-8-O-primveroside), C-glucoflavones (isoorientin and isoorientin- 4-O-glycoside) and secoridoids. The incidences of micronuclei, cell proliferation, apoptosis and lipid peroxidation products were examined. Isoorientin, isoorientin- 4-O-glycoside and norswertianin-1-O-primveroside showed antioxidant properties, whereas norswertianin-8-O-primveroside and gentiacaulein exhibited pro-oxidative effects. Gentiakochianin exhibited cytostatic effects in irradiated lymphocytes. These results contribute to the search for novel radioprotective agents.",
journal = "Current Science",
title = "Radioprotective properties of Gentiana dinarica polyphenols on human lymphocytes in vitro",
volume = "95",
number = "8",
pages = "1035-1041",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3567"
}

Petrović, S., Leskovac, A.,& Joksić, G.. (2008). Radioprotective properties of Gentiana dinarica polyphenols on human lymphocytes in vitro. in Current Science, 95(8), 1035-1041.
https://hdl.handle.net/21.15107/rcub_vinar_3567

Petrović S, Leskovac A, Joksić G. Radioprotective properties of Gentiana dinarica polyphenols on human lymphocytes in vitro. in Current Science. 2008;95(8):1035-1041.
https://hdl.handle.net/21.15107/rcub_vinar_3567 .

Petrović, Sandra, Leskovac, Andreja, Joksić, Gordana, "Radioprotective properties of Gentiana dinarica polyphenols on human lymphocytes in vitro" in Current Science, 95, no. 8 (2008):1035-1041,
https://hdl.handle.net/21.15107/rcub_vinar_3567 .