TY  - JOUR
AU  - Baralić, Ivana
AU  - Stojmenović, Tamara
AU  - Anđelković, Marija
AU  - Đorđević, Brižita
AU  - Dikić, Nenad
AU  - Radojević-Škodrić, Sanja
AU  - Pejić, Snežana
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8792
AB  - Introduction/Objective We determined the impact of antioxidant supplementation by GE132® on sports performance, oxidative stress markers, and muscle enzymes activities in professional female basketball players. Methods Repetitive strength, explosive power, anaerobic endurance, and agility performance were measured before/after the 45-day supplementation period. The FORT (Free Oxygen Radicals Test) and FORD analysis (Free Oxygen Radical Defense) were assessed before/after basketball specific exercise bout, at the beginning/end of observational period. The grade of muscle damage was evaluated by aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH). Results After supplementation period, significant difference was not recorded regarding the basic motor skills tests. Basketball specific exercise bout induced significant increase in FORT (p < 0.05) only at the beginning of supplementation period. Both FORT and FORD significantly decreased over the observational period (p < 0.001, p < 0.01, respectively). CK and LDH were remarkably lower at the end of observational period (p < 0.05), compared to the baseline. Conclusion Exogenous supplementation with protective nutraceuticals such as those found in GE132®, could reduce acute/chronic oxidative stress and muscle damage, but had no effect on sport performance in basketball players. © 2019, Serbia Medical Society. All rights reserved.
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players
VL  - 147
IS  - 11-12
SP  - 729
EP  - 735
DO  - 10.2298/SARH190118063B
ER  - 

@article{
author = "Baralić, Ivana and Stojmenović, Tamara and Anđelković, Marija and Đorđević, Brižita and Dikić, Nenad and Radojević-Škodrić, Sanja and Pejić, Snežana",
year = "2019",
abstract = "Introduction/Objective We determined the impact of antioxidant supplementation by GE132® on sports performance, oxidative stress markers, and muscle enzymes activities in professional female basketball players. Methods Repetitive strength, explosive power, anaerobic endurance, and agility performance were measured before/after the 45-day supplementation period. The FORT (Free Oxygen Radicals Test) and FORD analysis (Free Oxygen Radical Defense) were assessed before/after basketball specific exercise bout, at the beginning/end of observational period. The grade of muscle damage was evaluated by aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH). Results After supplementation period, significant difference was not recorded regarding the basic motor skills tests. Basketball specific exercise bout induced significant increase in FORT (p < 0.05) only at the beginning of supplementation period. Both FORT and FORD significantly decreased over the observational period (p < 0.001, p < 0.01, respectively). CK and LDH were remarkably lower at the end of observational period (p < 0.05), compared to the baseline. Conclusion Exogenous supplementation with protective nutraceuticals such as those found in GE132®, could reduce acute/chronic oxidative stress and muscle damage, but had no effect on sport performance in basketball players. © 2019, Serbia Medical Society. All rights reserved.",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players",
volume = "147",
number = "11-12",
pages = "729-735",
doi = "10.2298/SARH190118063B"
}

Baralić, I., Stojmenović, T., Anđelković, M., Đorđević, B., Dikić, N., Radojević-Škodrić, S.,& Pejić, S.. (2019). Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players. in Srpski arhiv za celokupno lekarstvo, 147(11-12), 729-735.
https://doi.org/10.2298/SARH190118063B

Baralić I, Stojmenović T, Anđelković M, Đorđević B, Dikić N, Radojević-Škodrić S, Pejić S. Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players. in Srpski arhiv za celokupno lekarstvo. 2019;147(11-12):729-735.
doi:10.2298/SARH190118063B .

Baralić, Ivana, Stojmenović, Tamara, Anđelković, Marija, Đorđević, Brižita, Dikić, Nenad, Radojević-Škodrić, Sanja, Pejić, Snežana, "Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players" in Srpski arhiv za celokupno lekarstvo, 147, no. 11-12 (2019):729-735,
https://doi.org/10.2298/SARH190118063B . .

TY  - JOUR
AU  - Čakar, Uroš
AU  - Grozdanić, Nađa
AU  - Petrović, Aleksandar V.
AU  - Pejin, Boris
AU  - Nastasijević, Branislav J.
AU  - Marković, Bojan D.
AU  - Đorđević, Brižita
PY  - 2018
UR  - http://www.eurekaselect.com/161153/article
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7860
AB  - BACKGROUND: Fruit wines are well known for their profound health-promoting properties including both enzyme activations and inhibitions. They may act preventive in regard to diabetes melitus and other chronic diseases. OBJECTIVES: Potential α-glucosidase inhibitory activity of fruit wines made from blueberry, black chokeberry, blackberry, raspberry and sour cherry was the subject of this study. METHOD: In order to increase the alcohol content due to enriched extraction of total phenolics, sugar was added in the fruit pomace of the half of the examined fruit wine samples. RESULTS: Compared with acarbose used as a positive control (IC50 = 73.78 µg/mL), all fruit wine samples exhibited higher α-glucosidase inhibitory activity. Indeed, blueberry wine samples stood out, both prepared with IC50 = 24.14 µg/mL, lyophilised extract yield 3.23% and without IC50 = 46.39 µg/mL, lyophilised extract yield 2.89% and with addition of sugar before fermentation. Chlorogenic acid predominantly contributed to α-glucosidase inhibitory activity of the blueberry, black chokeberry and sour cherry wine samples. However, ellagic acid, a potent α-glucosidase inhibitor possessing a planar structure, only slightly affected the activity of the blueberry wine samples, due to the lower concentration. In addition to this, molecular docking study of chlorogenic acid pointed out the importance of binding energy (-8.5 kcal/mol) for the inhibition of the enzyme. CONCLUSION: In summary, fruit wines made from blueberry should be primarily taken into consideration as a medicinal food targeting diabetes mellitus type 2 in the early stage, if additional studies would confirm their therapeutic potential for the control of postprandial hyperglycemia. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
T2  - Current Pharmaceutical Biotechnology
T1  - Fruit Wines Inhibitory Activity Against α-Glucosidase
VL  - 18
IS  - 15
SP  - 1264
EP  - 1272
DO  - 10.2174/1389201019666180410112439
ER  - 

@article{
author = "Čakar, Uroš and Grozdanić, Nađa and Petrović, Aleksandar V. and Pejin, Boris and Nastasijević, Branislav J. and Marković, Bojan D. and Đorđević, Brižita",
year = "2018",
abstract = "BACKGROUND: Fruit wines are well known for their profound health-promoting properties including both enzyme activations and inhibitions. They may act preventive in regard to diabetes melitus and other chronic diseases. OBJECTIVES: Potential α-glucosidase inhibitory activity of fruit wines made from blueberry, black chokeberry, blackberry, raspberry and sour cherry was the subject of this study. METHOD: In order to increase the alcohol content due to enriched extraction of total phenolics, sugar was added in the fruit pomace of the half of the examined fruit wine samples. RESULTS: Compared with acarbose used as a positive control (IC50 = 73.78 µg/mL), all fruit wine samples exhibited higher α-glucosidase inhibitory activity. Indeed, blueberry wine samples stood out, both prepared with IC50 = 24.14 µg/mL, lyophilised extract yield 3.23% and without IC50 = 46.39 µg/mL, lyophilised extract yield 2.89% and with addition of sugar before fermentation. Chlorogenic acid predominantly contributed to α-glucosidase inhibitory activity of the blueberry, black chokeberry and sour cherry wine samples. However, ellagic acid, a potent α-glucosidase inhibitor possessing a planar structure, only slightly affected the activity of the blueberry wine samples, due to the lower concentration. In addition to this, molecular docking study of chlorogenic acid pointed out the importance of binding energy (-8.5 kcal/mol) for the inhibition of the enzyme. CONCLUSION: In summary, fruit wines made from blueberry should be primarily taken into consideration as a medicinal food targeting diabetes mellitus type 2 in the early stage, if additional studies would confirm their therapeutic potential for the control of postprandial hyperglycemia. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.",
journal = "Current Pharmaceutical Biotechnology",
title = "Fruit Wines Inhibitory Activity Against α-Glucosidase",
volume = "18",
number = "15",
pages = "1264-1272",
doi = "10.2174/1389201019666180410112439"
}

Čakar, U., Grozdanić, N., Petrović, A. V., Pejin, B., Nastasijević, B. J., Marković, B. D.,& Đorđević, B.. (2018). Fruit Wines Inhibitory Activity Against α-Glucosidase. in Current Pharmaceutical Biotechnology, 18(15), 1264-1272.
https://doi.org/10.2174/1389201019666180410112439

Čakar U, Grozdanić N, Petrović AV, Pejin B, Nastasijević BJ, Marković BD, Đorđević B. Fruit Wines Inhibitory Activity Against α-Glucosidase. in Current Pharmaceutical Biotechnology. 2018;18(15):1264-1272.
doi:10.2174/1389201019666180410112439 .

Čakar, Uroš, Grozdanić, Nađa, Petrović, Aleksandar V., Pejin, Boris, Nastasijević, Branislav J., Marković, Bojan D., Đorđević, Brižita, "Fruit Wines Inhibitory Activity Against α-Glucosidase" in Current Pharmaceutical Biotechnology, 18, no. 15 (2018):1264-1272,
https://doi.org/10.2174/1389201019666180410112439 . .

TY  - JOUR
AU  - Baralic, Ivana
AU  - Anđelković, Marija
AU  - Đorđević, Brižita
AU  - Dikic, Nenad
AU  - Radivojevic, Nenad
AU  - Suzin-Zivkovic, Violeta
AU  - Radojević-Škodrić, Sanja
AU  - Pejić, Snežana
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/639
AB  - The physiologic stress induced by physical activity is reflected in immune systemperturbations, oxidative stress, muscle injury, and inflammation. We investigated the effect of astaxanthin (Asx) supplementation on salivary IgA (sIgA) and oxidative stress status in plasma, along with changes in biochemical parameters and total/differential white cell counts. Forty trained male soccer players were randomly assigned to Asx and placebo groups. Asx group was supplemented with 4mg of Asx. Saliva and blood samples were collected at the baseline and after 90 days of supplementation in preexercise conditions. We observed a rise of sIgA levels at rest after 90 days of Asx supplementation, which was accompanied with a decrease in prooxidant-antioxidant balance. The plasma muscle enzymes levels were reduced significantly by Asx supplementation and by regular training. The increase in neutrophil count and hs-CRP level was found only in placebo group, indicating a significant blunting of the systemic inflammatory response in the subjects taking Asx. This study indicates that Asx supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training. Our findings also point that Asx could show significant physiologic modulation in individuals with mucosal immunity impairment or under conditions of increased oxidative stress and inflammation.
T2  - Evidence-based Complementary and Alternative Medicine / eCAM
T1  - Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players
DO  - 10.1155/2015/783761
ER  - 

@article{
author = "Baralic, Ivana and Anđelković, Marija and Đorđević, Brižita and Dikic, Nenad and Radivojevic, Nenad and Suzin-Zivkovic, Violeta and Radojević-Škodrić, Sanja and Pejić, Snežana",
year = "2015",
abstract = "The physiologic stress induced by physical activity is reflected in immune systemperturbations, oxidative stress, muscle injury, and inflammation. We investigated the effect of astaxanthin (Asx) supplementation on salivary IgA (sIgA) and oxidative stress status in plasma, along with changes in biochemical parameters and total/differential white cell counts. Forty trained male soccer players were randomly assigned to Asx and placebo groups. Asx group was supplemented with 4mg of Asx. Saliva and blood samples were collected at the baseline and after 90 days of supplementation in preexercise conditions. We observed a rise of sIgA levels at rest after 90 days of Asx supplementation, which was accompanied with a decrease in prooxidant-antioxidant balance. The plasma muscle enzymes levels were reduced significantly by Asx supplementation and by regular training. The increase in neutrophil count and hs-CRP level was found only in placebo group, indicating a significant blunting of the systemic inflammatory response in the subjects taking Asx. This study indicates that Asx supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training. Our findings also point that Asx could show significant physiologic modulation in individuals with mucosal immunity impairment or under conditions of increased oxidative stress and inflammation.",
journal = "Evidence-based Complementary and Alternative Medicine / eCAM",
title = "Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players",
doi = "10.1155/2015/783761"
}

Baralic, I., Anđelković, M., Đorđević, B., Dikic, N., Radivojevic, N., Suzin-Zivkovic, V., Radojević-Škodrić, S.,& Pejić, S.. (2015). Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. in Evidence-based Complementary and Alternative Medicine / eCAM.
https://doi.org/10.1155/2015/783761

Baralic I, Anđelković M, Đorđević B, Dikic N, Radivojevic N, Suzin-Zivkovic V, Radojević-Škodrić S, Pejić S. Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. in Evidence-based Complementary and Alternative Medicine / eCAM. 2015;.
doi:10.1155/2015/783761 .

Baralic, Ivana, Anđelković, Marija, Đorđević, Brižita, Dikic, Nenad, Radivojevic, Nenad, Suzin-Zivkovic, Violeta, Radojević-Škodrić, Sanja, Pejić, Snežana, "Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players" in Evidence-based Complementary and Alternative Medicine / eCAM (2015),
https://doi.org/10.1155/2015/783761 . .

TY  - JOUR
AU  - Lević, Steva
AU  - Obradović, Nina
AU  - Pavlović, Vladimir B.
AU  - Isailovic, Bojana
AU  - Kostic, Ivana
AU  - Mitrić, Miodrag
AU  - Bugarski, Branko M.
AU  - Nedovic, Viktor
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/183
AB  - In this study, polyvinyl alcohol (PVA) nanofibers with ethyl vanillin as an active compound were prepared using electrospinning technique. The final products of electrospinning process were in the form of nanofibers films. PVA/ethyl vanillin nanofibers, having fibers diameters in the range 100-1700 nm, were successfully electrospun from ethanol/water mixture of PVA and ethyl vanillin. The effects of immobilization process on ethyl vanillin thermal properties were investigated by differential scanning calorimetry (DSC). The results of DSC showed significant influence of immobilization process on thermal properties of ethyl vanillin. It was noticed that melting point of immobilized ethyl vanillin was lower (similar to 55 A degrees C) compared to free flavor (similar to 77 A degrees C). Our results showed that films based on PVA/ethyl vanillin nanofibers are mechanically stable.
T2  - Journal of Thermal Analysis and Calorimetry
T1  - Thermal, morphological, and mechanical properties of ethyl vanillin immobilized in polyvinyl alcohol by electrospinning process
VL  - 118
IS  - 2
SP  - 661
EP  - 668
DO  - 10.1007/s10973-014-4060-4
ER  - 

@article{
author = "Lević, Steva and Obradović, Nina and Pavlović, Vladimir B. and Isailovic, Bojana and Kostic, Ivana and Mitrić, Miodrag and Bugarski, Branko M. and Nedovic, Viktor",
year = "2014",
abstract = "In this study, polyvinyl alcohol (PVA) nanofibers with ethyl vanillin as an active compound were prepared using electrospinning technique. The final products of electrospinning process were in the form of nanofibers films. PVA/ethyl vanillin nanofibers, having fibers diameters in the range 100-1700 nm, were successfully electrospun from ethanol/water mixture of PVA and ethyl vanillin. The effects of immobilization process on ethyl vanillin thermal properties were investigated by differential scanning calorimetry (DSC). The results of DSC showed significant influence of immobilization process on thermal properties of ethyl vanillin. It was noticed that melting point of immobilized ethyl vanillin was lower (similar to 55 A degrees C) compared to free flavor (similar to 77 A degrees C). Our results showed that films based on PVA/ethyl vanillin nanofibers are mechanically stable.",
journal = "Journal of Thermal Analysis and Calorimetry",
title = "Thermal, morphological, and mechanical properties of ethyl vanillin immobilized in polyvinyl alcohol by electrospinning process",
volume = "118",
number = "2",
pages = "661-668",
doi = "10.1007/s10973-014-4060-4"
}

Lević, S., Obradović, N., Pavlović, V. B., Isailovic, B., Kostic, I., Mitrić, M., Bugarski, B. M.,& Nedovic, V.. (2014). Thermal, morphological, and mechanical properties of ethyl vanillin immobilized in polyvinyl alcohol by electrospinning process. in Journal of Thermal Analysis and Calorimetry, 118(2), 661-668.
https://doi.org/10.1007/s10973-014-4060-4

Lević S, Obradović N, Pavlović VB, Isailovic B, Kostic I, Mitrić M, Bugarski BM, Nedovic V. Thermal, morphological, and mechanical properties of ethyl vanillin immobilized in polyvinyl alcohol by electrospinning process. in Journal of Thermal Analysis and Calorimetry. 2014;118(2):661-668.
doi:10.1007/s10973-014-4060-4 .

Lević, Steva, Obradović, Nina, Pavlović, Vladimir B., Isailovic, Bojana, Kostic, Ivana, Mitrić, Miodrag, Bugarski, Branko M., Nedovic, Viktor, "Thermal, morphological, and mechanical properties of ethyl vanillin immobilized in polyvinyl alcohol by electrospinning process" in Journal of Thermal Analysis and Calorimetry, 118, no. 2 (2014):661-668,
https://doi.org/10.1007/s10973-014-4060-4 . .

TY  - JOUR
AU  - Baralic, Ivana
AU  - Đorđević, Brižita
AU  - Dikic, Nenad
AU  - Kotur-Stevuljevic, Jelena
AU  - Spasic, Slavica
AU  - Jelić-Ivanović, Zorana
AU  - Radivojevic, Nenad
AU  - Anđelković, Marija
AU  - Pejić, Snežana
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5713
AB  - The purpose of the study was to examine the effects of astaxanthin (Asx) on paraoxonase (PON1) activities and oxidative stress status in soccer players. Forty soccer players were randomly assigned in a double-blind fashion to Asx and placebo (P) group. Blood samples were obtained before, 45 and 90days after supplementation. PON1 activity was assessed by using two substrates: paraoxon and diazoxon. The oxidative stress biomarkers were also examined: total sulphydryl group content (-SH groups), thiobarbituric acid-reactive substances (TBARS), advanced oxidation protein products and redox balance. The significant interaction effect of supplementation and training (p LT 0.05) on PON1 activity toward paraoxon was observed. The PON1 activity toward diazoxon increased in Asx group after 90days (p LT 0.01), while there was no significant difference in P group. SH groups content rose from pre- to post-supplementation period only in Asx group (supplementation and training, p LT 0.05; training, p LT 0.01). TBARS levels decreased after 45days and increased after 90days of regular soccer training in both groups (training, p LT 0.001). Redox balance decreased significantly in response to the regular training, regardless of treatment group (training, p LT 0.001). Asx supplementation might increase total SH groups content and improve PON1 activity through protection of free thiol groups against oxidative modification. Copyright (c) 2012 John Wiley and Sons, Ltd.
T2  - Phytotherapy Research
T1  - Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players
VL  - 27
IS  - 10
SP  - 1536
EP  - 1542
DO  - 10.1002/ptr.4898
ER  - 

@article{
author = "Baralic, Ivana and Đorđević, Brižita and Dikic, Nenad and Kotur-Stevuljevic, Jelena and Spasic, Slavica and Jelić-Ivanović, Zorana and Radivojevic, Nenad and Anđelković, Marija and Pejić, Snežana",
year = "2013",
abstract = "The purpose of the study was to examine the effects of astaxanthin (Asx) on paraoxonase (PON1) activities and oxidative stress status in soccer players. Forty soccer players were randomly assigned in a double-blind fashion to Asx and placebo (P) group. Blood samples were obtained before, 45 and 90days after supplementation. PON1 activity was assessed by using two substrates: paraoxon and diazoxon. The oxidative stress biomarkers were also examined: total sulphydryl group content (-SH groups), thiobarbituric acid-reactive substances (TBARS), advanced oxidation protein products and redox balance. The significant interaction effect of supplementation and training (p LT 0.05) on PON1 activity toward paraoxon was observed. The PON1 activity toward diazoxon increased in Asx group after 90days (p LT 0.01), while there was no significant difference in P group. SH groups content rose from pre- to post-supplementation period only in Asx group (supplementation and training, p LT 0.05; training, p LT 0.01). TBARS levels decreased after 45days and increased after 90days of regular soccer training in both groups (training, p LT 0.001). Redox balance decreased significantly in response to the regular training, regardless of treatment group (training, p LT 0.001). Asx supplementation might increase total SH groups content and improve PON1 activity through protection of free thiol groups against oxidative modification. Copyright (c) 2012 John Wiley and Sons, Ltd.",
journal = "Phytotherapy Research",
title = "Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players",
volume = "27",
number = "10",
pages = "1536-1542",
doi = "10.1002/ptr.4898"
}

Baralic, I., Đorđević, B., Dikic, N., Kotur-Stevuljevic, J., Spasic, S., Jelić-Ivanović, Z., Radivojevic, N., Anđelković, M.,& Pejić, S.. (2013). Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players. in Phytotherapy Research, 27(10), 1536-1542.
https://doi.org/10.1002/ptr.4898

Baralic I, Đorđević B, Dikic N, Kotur-Stevuljevic J, Spasic S, Jelić-Ivanović Z, Radivojevic N, Anđelković M, Pejić S. Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players. in Phytotherapy Research. 2013;27(10):1536-1542.
doi:10.1002/ptr.4898 .

Baralic, Ivana, Đorđević, Brižita, Dikic, Nenad, Kotur-Stevuljevic, Jelena, Spasic, Slavica, Jelić-Ivanović, Zorana, Radivojevic, Nenad, Anđelković, Marija, Pejić, Snežana, "Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players" in Phytotherapy Research, 27, no. 10 (2013):1536-1542,
https://doi.org/10.1002/ptr.4898 . .