TY  - JOUR
AU  - Veljković, Milena
AU  - Dopsaj, V.
AU  - Stringer, W. W.
AU  - Sakarellos-Daitsiotis, M.
AU  - Zevgiti, S.
AU  - Veljković, Veljko
AU  - Glišić, Sanja
AU  - Dopsaj, M.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4005
AB  - Despite the effectiveness of HAART in controlling HIV-1 replication, the emergence of drug-resistant viruses in infected patients and the severe side effects caused by the currently used drug regimens and the lack of an effective vaccine necessitate the continued search for new therapeutic strategies for prevention and therapy of HIV disease. Previously we reported that natural autoantibodies, recognizing peptide FTDNAKTI (peptide NTM1) derived from the C2 domain of HIV-1 gp120, contribute to the control of HIV disease. Here we demonstrated that sera from well-trained athletic (HIV-negative) subjects showed high reactivity with peptide NTM1. This result confirms that aerobic exercise training stimulates production of natural autoantibodies, which recognize peptide NTM1. Bioinformatics analysis indicates that these natural autoantibodies could slow down disease progression by blocking the superantigenic site on HIV-1 gp120. The results suggest that aerobic exercise training may be a promising non-toxic and inexpensive adjunctive anti-HIV therapy.
T2  - Scandinavian Journal of Medicine and Science in Sports
T1  - Aerobic exercise training as a potential source of natural antibodies protective against human immunodeficiency virus-1
VL  - 20
IS  - 3
SP  - 469
EP  - 474
DO  - 10.1111/j.1600-0838.2009.00962.x
ER  - 

@article{
author = "Veljković, Milena and Dopsaj, V. and Stringer, W. W. and Sakarellos-Daitsiotis, M. and Zevgiti, S. and Veljković, Veljko and Glišić, Sanja and Dopsaj, M.",
year = "2010",
abstract = "Despite the effectiveness of HAART in controlling HIV-1 replication, the emergence of drug-resistant viruses in infected patients and the severe side effects caused by the currently used drug regimens and the lack of an effective vaccine necessitate the continued search for new therapeutic strategies for prevention and therapy of HIV disease. Previously we reported that natural autoantibodies, recognizing peptide FTDNAKTI (peptide NTM1) derived from the C2 domain of HIV-1 gp120, contribute to the control of HIV disease. Here we demonstrated that sera from well-trained athletic (HIV-negative) subjects showed high reactivity with peptide NTM1. This result confirms that aerobic exercise training stimulates production of natural autoantibodies, which recognize peptide NTM1. Bioinformatics analysis indicates that these natural autoantibodies could slow down disease progression by blocking the superantigenic site on HIV-1 gp120. The results suggest that aerobic exercise training may be a promising non-toxic and inexpensive adjunctive anti-HIV therapy.",
journal = "Scandinavian Journal of Medicine and Science in Sports",
title = "Aerobic exercise training as a potential source of natural antibodies protective against human immunodeficiency virus-1",
volume = "20",
number = "3",
pages = "469-474",
doi = "10.1111/j.1600-0838.2009.00962.x"
}

Veljković, M., Dopsaj, V., Stringer, W. W., Sakarellos-Daitsiotis, M., Zevgiti, S., Veljković, V., Glišić, S.,& Dopsaj, M.. (2010). Aerobic exercise training as a potential source of natural antibodies protective against human immunodeficiency virus-1. in Scandinavian Journal of Medicine and Science in Sports, 20(3), 469-474.
https://doi.org/10.1111/j.1600-0838.2009.00962.x

Veljković M, Dopsaj V, Stringer WW, Sakarellos-Daitsiotis M, Zevgiti S, Veljković V, Glišić S, Dopsaj M. Aerobic exercise training as a potential source of natural antibodies protective against human immunodeficiency virus-1. in Scandinavian Journal of Medicine and Science in Sports. 2010;20(3):469-474.
doi:10.1111/j.1600-0838.2009.00962.x .

Veljković, Milena, Dopsaj, V., Stringer, W. W., Sakarellos-Daitsiotis, M., Zevgiti, S., Veljković, Veljko, Glišić, Sanja, Dopsaj, M., "Aerobic exercise training as a potential source of natural antibodies protective against human immunodeficiency virus-1" in Scandinavian Journal of Medicine and Science in Sports, 20, no. 3 (2010):469-474,
https://doi.org/10.1111/j.1600-0838.2009.00962.x . .

TY  - CONF
AU  - Zevgiti, S.
AU  - Krikorian, D.
AU  - Panou-Pomonis, E.
AU  - Veljković, Veljko
AU  - Sakarellos-Daitsiotis, M.
AU  - Sakarellos, C.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3067
C3  - Journal of Peptide Science
T1  - Development of diagnostics and vaccine candidates for the highly pathogenic H5N1 influenza virus
VL  - 12
SP  - 226
EP  - 226
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3067
ER  - 

@conference{
author = "Zevgiti, S. and Krikorian, D. and Panou-Pomonis, E. and Veljković, Veljko and Sakarellos-Daitsiotis, M. and Sakarellos, C.",
year = "2006",
journal = "Journal of Peptide Science",
title = "Development of diagnostics and vaccine candidates for the highly pathogenic H5N1 influenza virus",
volume = "12",
pages = "226-226",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3067"
}

Zevgiti, S., Krikorian, D., Panou-Pomonis, E., Veljković, V., Sakarellos-Daitsiotis, M.,& Sakarellos, C.. (2006). Development of diagnostics and vaccine candidates for the highly pathogenic H5N1 influenza virus. in Journal of Peptide Science, 12, 226-226.
https://hdl.handle.net/21.15107/rcub_vinar_3067

Zevgiti S, Krikorian D, Panou-Pomonis E, Veljković V, Sakarellos-Daitsiotis M, Sakarellos C. Development of diagnostics and vaccine candidates for the highly pathogenic H5N1 influenza virus. in Journal of Peptide Science. 2006;12:226-226.
https://hdl.handle.net/21.15107/rcub_vinar_3067 .

Zevgiti, S., Krikorian, D., Panou-Pomonis, E., Veljković, Veljko, Sakarellos-Daitsiotis, M., Sakarellos, C., "Development of diagnostics and vaccine candidates for the highly pathogenic H5N1 influenza virus" in Journal of Peptide Science, 12 (2006):226-226,
https://hdl.handle.net/21.15107/rcub_vinar_3067 .

TY  - CONF
AU  - Krikorian, D.
AU  - Zevgiti, S.
AU  - Veljković, Veljko
AU  - Sakarellos-Daitsiotis, M.
AU  - Sakarellos, C.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3068
C3  - Journal of Peptide Science
T1  - Development of a diagnostic immunoassay for the detection of natural anti-NTM/VIP antibodies of HIV-1
VL  - 12
SP  - 231
EP  - 231
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3068
ER  - 

@conference{
author = "Krikorian, D. and Zevgiti, S. and Veljković, Veljko and Sakarellos-Daitsiotis, M. and Sakarellos, C.",
year = "2006",
journal = "Journal of Peptide Science",
title = "Development of a diagnostic immunoassay for the detection of natural anti-NTM/VIP antibodies of HIV-1",
volume = "12",
pages = "231-231",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3068"
}

Krikorian, D., Zevgiti, S., Veljković, V., Sakarellos-Daitsiotis, M.,& Sakarellos, C.. (2006). Development of a diagnostic immunoassay for the detection of natural anti-NTM/VIP antibodies of HIV-1. in Journal of Peptide Science, 12, 231-231.
https://hdl.handle.net/21.15107/rcub_vinar_3068

Krikorian D, Zevgiti S, Veljković V, Sakarellos-Daitsiotis M, Sakarellos C. Development of a diagnostic immunoassay for the detection of natural anti-NTM/VIP antibodies of HIV-1. in Journal of Peptide Science. 2006;12:231-231.
https://hdl.handle.net/21.15107/rcub_vinar_3068 .

Krikorian, D., Zevgiti, S., Veljković, Veljko, Sakarellos-Daitsiotis, M., Sakarellos, C., "Development of a diagnostic immunoassay for the detection of natural anti-NTM/VIP antibodies of HIV-1" in Journal of Peptide Science, 12 (2006):231-231,
https://hdl.handle.net/21.15107/rcub_vinar_3068 .