TY  - JOUR
AU  - Bogdanović, Una
AU  - Vodnik, Vesna
AU  - Mitrić, Miodrag
AU  - Dimitrijević, Suzana I.
AU  - Škapin, Srečo Davor
AU  - Zunic, Vojka
AU  - Budimir, Milica
AU  - Stoiljković, Milovan
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/376
AB  - This study explores different mechanisms of antimicrobial action by designing hybrid nanomaterials that provide a new approach in the fight against resistant microbes. Here, we present a cheap copper-polyaniline (Cu-PANI) nanocomposite material with enhanced antimicrobial properties, prepared by simple in situ polymerization method, when polymer and metal nanoparticles are produced simultaneously. The copper nanoparticles (CuNPs) are uniformly dispersed in the polymer and have a narrow size distribution (dav = 6 nm). We found that CuNPs and PANI act synergistically against three strains, Escherichia coli, Staphylococcus aureus, and Candida albicans, and resulting nanocomposite exhibits higher antimicrobial activity than any component acting alone. Before using the colony counting method to quantify its time and concentration antimicrobial activity, different techniques (UV-visible spectroscopy, transmission electron microscopy, scanning electron microscope, field emission scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectrophotometry, and inductively coupled plasma optical emission spectrometry) were used to identify the optical, structural, and chemical aspects of the formed Cu-PANI nanocomposite. The antimicrobial activity of this nanocomposite shows that the microbial growth has been fully inhibited; moreover, some of the tested microbes were killed. Atomic force microscopy revealed dramatic changes in morphology of tested cells due to disruption of their cell wall integrity after incubation with Cu-PANI nanocomposite.
T2  - ACS Applied Materials and Interfaces
T1  - Nanomaterial with High Antimicrobial Efficacy-Copper/Polyaniline Nanocomposite
VL  - 7
IS  - 3
SP  - 1955
EP  - 1966
DO  - 10.1021/am507746m
ER  - 

@article{
author = "Bogdanović, Una and Vodnik, Vesna and Mitrić, Miodrag and Dimitrijević, Suzana I. and Škapin, Srečo Davor and Zunic, Vojka and Budimir, Milica and Stoiljković, Milovan",
year = "2015",
abstract = "This study explores different mechanisms of antimicrobial action by designing hybrid nanomaterials that provide a new approach in the fight against resistant microbes. Here, we present a cheap copper-polyaniline (Cu-PANI) nanocomposite material with enhanced antimicrobial properties, prepared by simple in situ polymerization method, when polymer and metal nanoparticles are produced simultaneously. The copper nanoparticles (CuNPs) are uniformly dispersed in the polymer and have a narrow size distribution (dav = 6 nm). We found that CuNPs and PANI act synergistically against three strains, Escherichia coli, Staphylococcus aureus, and Candida albicans, and resulting nanocomposite exhibits higher antimicrobial activity than any component acting alone. Before using the colony counting method to quantify its time and concentration antimicrobial activity, different techniques (UV-visible spectroscopy, transmission electron microscopy, scanning electron microscope, field emission scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectrophotometry, and inductively coupled plasma optical emission spectrometry) were used to identify the optical, structural, and chemical aspects of the formed Cu-PANI nanocomposite. The antimicrobial activity of this nanocomposite shows that the microbial growth has been fully inhibited; moreover, some of the tested microbes were killed. Atomic force microscopy revealed dramatic changes in morphology of tested cells due to disruption of their cell wall integrity after incubation with Cu-PANI nanocomposite.",
journal = "ACS Applied Materials and Interfaces",
title = "Nanomaterial with High Antimicrobial Efficacy-Copper/Polyaniline Nanocomposite",
volume = "7",
number = "3",
pages = "1955-1966",
doi = "10.1021/am507746m"
}

Bogdanović, U., Vodnik, V., Mitrić, M., Dimitrijević, S. I., Škapin, S. D., Zunic, V., Budimir, M.,& Stoiljković, M.. (2015). Nanomaterial with High Antimicrobial Efficacy-Copper/Polyaniline Nanocomposite. in ACS Applied Materials and Interfaces, 7(3), 1955-1966.
https://doi.org/10.1021/am507746m

Bogdanović U, Vodnik V, Mitrić M, Dimitrijević SI, Škapin SD, Zunic V, Budimir M, Stoiljković M. Nanomaterial with High Antimicrobial Efficacy-Copper/Polyaniline Nanocomposite. in ACS Applied Materials and Interfaces. 2015;7(3):1955-1966.
doi:10.1021/am507746m .

Bogdanović, Una, Vodnik, Vesna, Mitrić, Miodrag, Dimitrijević, Suzana I., Škapin, Srečo Davor, Zunic, Vojka, Budimir, Milica, Stoiljković, Milovan, "Nanomaterial with High Antimicrobial Efficacy-Copper/Polyaniline Nanocomposite" in ACS Applied Materials and Interfaces, 7, no. 3 (2015):1955-1966,
https://doi.org/10.1021/am507746m . .