TY  - JOUR
AU  - Motorzhina, Anna
AU  - Jovanović, Sonja
AU  - Belyaev, Victor K.
AU  - Murzin, Dmitry
AU  - Pshenichnikov, Stanislav
AU  - Kolesnikova, Valeria G.
AU  - Omelyanchik, Alexander S.
AU  - Gazvoda, Lea
AU  - Spreitzer, Matjaž
AU  - Panina, Larissa
AU  - Rodionova, Valeria
AU  - Vukomanović, Marija
AU  - Levada, Kateryna
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10099
AB  - The combination of plasmonic material and magnetic metal oxide nanoparticles is widely used in multifunctional nanosystems. Here we propose a method for the fabrication of a gold/cobalt ferrite nanocomposite for biomedical applications. The composite includes gold cores of ~10 nm in diameter coated with arginine, which are surrounded by small cobalt ferrite nanoparticles with diameters of ~5 nm covered with dihydrocaffeic acid. The structure and elemental composition, morphology and dimensions, magnetic and optical properties, and biocompatibility of new nanocomposite were studied. The magnetic properties of the composite are mostly determined by the superparamagnetic state of cobalt ferrite nanoparticles, and optical properties are influenced by the localized plasmon resonance in gold nanoparticles. The cytotoxicity of gold/cobalt ferrite nanocomposite was tested using T-lymphoblastic leukemia and peripheral blood mononuclear cells. Studied composite has selective citotoxic effect on cancerous cells while it has no cytotoxic effect on healtly cells. The results suggest that this material can be explored in the future for combined photothermal treatment and magnetic theranostic.
T2  - Processes
T1  - Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties
VL  - 9
IS  - 12
SP  - 2264
DO  - 10.3390/pr9122264
ER  - 

@article{
author = "Motorzhina, Anna and Jovanović, Sonja and Belyaev, Victor K. and Murzin, Dmitry and Pshenichnikov, Stanislav and Kolesnikova, Valeria G. and Omelyanchik, Alexander S. and Gazvoda, Lea and Spreitzer, Matjaž and Panina, Larissa and Rodionova, Valeria and Vukomanović, Marija and Levada, Kateryna",
year = "2021",
abstract = "The combination of plasmonic material and magnetic metal oxide nanoparticles is widely used in multifunctional nanosystems. Here we propose a method for the fabrication of a gold/cobalt ferrite nanocomposite for biomedical applications. The composite includes gold cores of ~10 nm in diameter coated with arginine, which are surrounded by small cobalt ferrite nanoparticles with diameters of ~5 nm covered with dihydrocaffeic acid. The structure and elemental composition, morphology and dimensions, magnetic and optical properties, and biocompatibility of new nanocomposite were studied. The magnetic properties of the composite are mostly determined by the superparamagnetic state of cobalt ferrite nanoparticles, and optical properties are influenced by the localized plasmon resonance in gold nanoparticles. The cytotoxicity of gold/cobalt ferrite nanocomposite was tested using T-lymphoblastic leukemia and peripheral blood mononuclear cells. Studied composite has selective citotoxic effect on cancerous cells while it has no cytotoxic effect on healtly cells. The results suggest that this material can be explored in the future for combined photothermal treatment and magnetic theranostic.",
journal = "Processes",
title = "Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties",
volume = "9",
number = "12",
pages = "2264",
doi = "10.3390/pr9122264"
}

Motorzhina, A., Jovanović, S., Belyaev, V. K., Murzin, D., Pshenichnikov, S., Kolesnikova, V. G., Omelyanchik, A. S., Gazvoda, L., Spreitzer, M., Panina, L., Rodionova, V., Vukomanović, M.,& Levada, K.. (2021). Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties. in Processes, 9(12), 2264.
https://doi.org/10.3390/pr9122264

Motorzhina A, Jovanović S, Belyaev VK, Murzin D, Pshenichnikov S, Kolesnikova VG, Omelyanchik AS, Gazvoda L, Spreitzer M, Panina L, Rodionova V, Vukomanović M, Levada K. Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties. in Processes. 2021;9(12):2264.
doi:10.3390/pr9122264 .

Motorzhina, Anna, Jovanović, Sonja, Belyaev, Victor K., Murzin, Dmitry, Pshenichnikov, Stanislav, Kolesnikova, Valeria G., Omelyanchik, Alexander S., Gazvoda, Lea, Spreitzer, Matjaž, Panina, Larissa, Rodionova, Valeria, Vukomanović, Marija, Levada, Kateryna, "Innovative Gold/Cobalt Ferrite Nanocomposite: Physicochemical and Cytotoxicity Properties" in Processes, 9, no. 12 (2021):2264,
https://doi.org/10.3390/pr9122264 . .

TY  - JOUR
AU  - Muscas, Giuseppe
AU  - Jovanović, Sonja
AU  - Vukomanović, Marija
AU  - Spreitzer, Matjaž
AU  - Peddis, Davide
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0925838819316147
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8194
AB  - Magnetic nanoparticles represent complex but very interesting objects. They combine the bulk properties with novel phenomena emerging at the nanoscale due to finite-size effects. The recent development of the synthetic procedures allows having a strong control on the size and shape of individual particles and on their physical-chemical structure. Among different magnetic materials, spinel ferrite nanoparticles offer strong chemical and physical stability as well as tunable magnetic properties. In the present article, we investigate the effect of Zn substitution in cobalt ferrite nanoparticles. The technological development of nanoparticle-based magnetic materials aims to find a balance between a well-defined magnetic behavior of individual elements and their strong interactions, which arise from the need of miniaturization that leads to dense ensembles of the system's constituents. Within this complex context, we provide one route to optimize the properties of small spinel ferrite particles by tuning their chemical composition without compromise their structural properties, and with full control of their size and shape. Furthermore, we propose an advanced analysis of their magnetic properties in the framework of the random anisotropy model. We will show that the chemical composition not only determines the intrinsic anisotropy energy of each nanoparticle but also owns a profound effect on the interparticle interactions. © 2019 Elsevier B.V.
T2  - Journal of Alloys and Compounds
T1  - Zn-doped cobalt ferrite: Tuning the interactions by chemical composition
VL  - 796
SP  - 203
EP  - 209
DO  - 10.1016/j.jallcom.2019.04.308
ER  - 

@article{
author = "Muscas, Giuseppe and Jovanović, Sonja and Vukomanović, Marija and Spreitzer, Matjaž and Peddis, Davide",
year = "2019",
abstract = "Magnetic nanoparticles represent complex but very interesting objects. They combine the bulk properties with novel phenomena emerging at the nanoscale due to finite-size effects. The recent development of the synthetic procedures allows having a strong control on the size and shape of individual particles and on their physical-chemical structure. Among different magnetic materials, spinel ferrite nanoparticles offer strong chemical and physical stability as well as tunable magnetic properties. In the present article, we investigate the effect of Zn substitution in cobalt ferrite nanoparticles. The technological development of nanoparticle-based magnetic materials aims to find a balance between a well-defined magnetic behavior of individual elements and their strong interactions, which arise from the need of miniaturization that leads to dense ensembles of the system's constituents. Within this complex context, we provide one route to optimize the properties of small spinel ferrite particles by tuning their chemical composition without compromise their structural properties, and with full control of their size and shape. Furthermore, we propose an advanced analysis of their magnetic properties in the framework of the random anisotropy model. We will show that the chemical composition not only determines the intrinsic anisotropy energy of each nanoparticle but also owns a profound effect on the interparticle interactions. © 2019 Elsevier B.V.",
journal = "Journal of Alloys and Compounds",
title = "Zn-doped cobalt ferrite: Tuning the interactions by chemical composition",
volume = "796",
pages = "203-209",
doi = "10.1016/j.jallcom.2019.04.308"
}

Muscas, G., Jovanović, S., Vukomanović, M., Spreitzer, M.,& Peddis, D.. (2019). Zn-doped cobalt ferrite: Tuning the interactions by chemical composition. in Journal of Alloys and Compounds, 796, 203-209.
https://doi.org/10.1016/j.jallcom.2019.04.308

Muscas G, Jovanović S, Vukomanović M, Spreitzer M, Peddis D. Zn-doped cobalt ferrite: Tuning the interactions by chemical composition. in Journal of Alloys and Compounds. 2019;796:203-209.
doi:10.1016/j.jallcom.2019.04.308 .

Muscas, Giuseppe, Jovanović, Sonja, Vukomanović, Marija, Spreitzer, Matjaž, Peddis, Davide, "Zn-doped cobalt ferrite: Tuning the interactions by chemical composition" in Journal of Alloys and Compounds, 796 (2019):203-209,
https://doi.org/10.1016/j.jallcom.2019.04.308 . .

TY  - JOUR
AU  - Jugović, Dragana
AU  - Mitrić, Miodrag
AU  - Milović, Miloš
AU  - Jokić, Bojan M.
AU  - Vukomanovic, Marija
AU  - Suvorov, Danilo
AU  - Uskoković, Dragan
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5670
AB  - In this study, nanocrystalline LiFePO4/C composite powder has been synthesized via a cellulose matrix-assisted method. In an experiment conducted under extreme conditions involving rapid heating, short high-temperature delay, and subsequent quenching, well-ordered 35-nm crystallites have been obtained within 5 min. A quantitative filter paper has served both as a template and carbon source. It degrades pyrolytically through fragmentation reactions and formation of volatiles when exposed to rapid heating, which further has an impact on powder morphology, as revealed by electron microscopy studies. The electrochemical measurements in terms of galvanostatic cycling have shown that the approach presented in this study may enable to reach good rate capability and excellent cycling stability. (C) 2013 Elsevier B.V. All rights reserved.
T2  - Powder Technology
T1  - Properties of quenched LiFePO4/C powder obtained via cellulose matrix-assisted method
VL  - 246
SP  - 539
EP  - 544
DO  - 10.1016/j.powtec.2013.06.021
ER  - 

@article{
author = "Jugović, Dragana and Mitrić, Miodrag and Milović, Miloš and Jokić, Bojan M. and Vukomanovic, Marija and Suvorov, Danilo and Uskoković, Dragan",
year = "2013",
abstract = "In this study, nanocrystalline LiFePO4/C composite powder has been synthesized via a cellulose matrix-assisted method. In an experiment conducted under extreme conditions involving rapid heating, short high-temperature delay, and subsequent quenching, well-ordered 35-nm crystallites have been obtained within 5 min. A quantitative filter paper has served both as a template and carbon source. It degrades pyrolytically through fragmentation reactions and formation of volatiles when exposed to rapid heating, which further has an impact on powder morphology, as revealed by electron microscopy studies. The electrochemical measurements in terms of galvanostatic cycling have shown that the approach presented in this study may enable to reach good rate capability and excellent cycling stability. (C) 2013 Elsevier B.V. All rights reserved.",
journal = "Powder Technology",
title = "Properties of quenched LiFePO4/C powder obtained via cellulose matrix-assisted method",
volume = "246",
pages = "539-544",
doi = "10.1016/j.powtec.2013.06.021"
}

Jugović, D., Mitrić, M., Milović, M., Jokić, B. M., Vukomanovic, M., Suvorov, D.,& Uskoković, D.. (2013). Properties of quenched LiFePO4/C powder obtained via cellulose matrix-assisted method. in Powder Technology, 246, 539-544.
https://doi.org/10.1016/j.powtec.2013.06.021

Jugović D, Mitrić M, Milović M, Jokić BM, Vukomanovic M, Suvorov D, Uskoković D. Properties of quenched LiFePO4/C powder obtained via cellulose matrix-assisted method. in Powder Technology. 2013;246:539-544.
doi:10.1016/j.powtec.2013.06.021 .

Jugović, Dragana, Mitrić, Miodrag, Milović, Miloš, Jokić, Bojan M., Vukomanovic, Marija, Suvorov, Danilo, Uskoković, Dragan, "Properties of quenched LiFePO4/C powder obtained via cellulose matrix-assisted method" in Powder Technology, 246 (2013):539-544,
https://doi.org/10.1016/j.powtec.2013.06.021 . .

TY  - JOUR
AU  - Vukomanović, Marija
AU  - Šarčev, Igor
AU  - Petronijević, B.
AU  - Škapin, Srečo Davor
AU  - Ignjatović, Nenad L.
AU  - Uskoković, Dragan
PY  - 2012
UR  - http://dais.sanu.ac.rs/123456789/490
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7452
AB  - The surface properties of PLGA/HAp core–shell nanoparticles loaded with clindamycin obtained by an ultrasonic processing method and their changes under the simulated physiological conditions during the degradation process (when the morphology is changed starting from the nanospheres, over micrometer-sized plate-like films to a porous network) were investigated. The dynamic change of the surface properties of this material obtained in a water environment showed an increase of the surface area (up to 70 m2/g) and an improved wettability (estimated water contact angle was in the range between 40° and 60°) suggesting the possibility for its good interaction with cells. The in vitro tests are in a good correlation with this hypothesis, showing a high level of cytocompatibility of the material with the mouse L929 and human lung MRC-5 fibroblasts. The fibroblasts were able to achieve the contact with the material's surface and to attach onto it. The significance of HAp, as the bioceramic phase within the PLGA/HAp core–shell nanoparticles, may be brought into relationship with its role in improving the surface properties of PLGA/HAp obtained during the degradation process. These properties are closely related to the bioactivity and biocompatibility of this material, which are highly relevant for its biomedical application.
PB  - Elsevier
T2  - Colloids and Surfaces. B: Biointerfaces
T1  - Poly(d,l-lactide-co-glycolide)/hydroxyapatite core–shell nanospheres. Part 4: A change of the surface properties during degradation process and the corresponding in vitro cellular response
SP  - 144
EP  - 153
DO  - 10.1016/j.colsurfb.2011.10.049
ER  - 

@article{
author = "Vukomanović, Marija and Šarčev, Igor and Petronijević, B. and Škapin, Srečo Davor and Ignjatović, Nenad L. and Uskoković, Dragan",
year = "2012",
abstract = "The surface properties of PLGA/HAp core–shell nanoparticles loaded with clindamycin obtained by an ultrasonic processing method and their changes under the simulated physiological conditions during the degradation process (when the morphology is changed starting from the nanospheres, over micrometer-sized plate-like films to a porous network) were investigated. The dynamic change of the surface properties of this material obtained in a water environment showed an increase of the surface area (up to 70 m2/g) and an improved wettability (estimated water contact angle was in the range between 40° and 60°) suggesting the possibility for its good interaction with cells. The in vitro tests are in a good correlation with this hypothesis, showing a high level of cytocompatibility of the material with the mouse L929 and human lung MRC-5 fibroblasts. The fibroblasts were able to achieve the contact with the material's surface and to attach onto it. The significance of HAp, as the bioceramic phase within the PLGA/HAp core–shell nanoparticles, may be brought into relationship with its role in improving the surface properties of PLGA/HAp obtained during the degradation process. These properties are closely related to the bioactivity and biocompatibility of this material, which are highly relevant for its biomedical application.",
publisher = "Elsevier",
journal = "Colloids and Surfaces. B: Biointerfaces",
title = "Poly(d,l-lactide-co-glycolide)/hydroxyapatite core–shell nanospheres. Part 4: A change of the surface properties during degradation process and the corresponding in vitro cellular response",
pages = "144-153",
doi = "10.1016/j.colsurfb.2011.10.049"
}

Vukomanović, M., Šarčev, I., Petronijević, B., Škapin, S. D., Ignjatović, N. L.,& Uskoković, D.. (2012). Poly(d,l-lactide-co-glycolide)/hydroxyapatite core–shell nanospheres. Part 4: A change of the surface properties during degradation process and the corresponding in vitro cellular response. in Colloids and Surfaces. B: Biointerfaces
Elsevier., 144-153.
https://doi.org/10.1016/j.colsurfb.2011.10.049

Vukomanović M, Šarčev I, Petronijević B, Škapin SD, Ignjatović NL, Uskoković D. Poly(d,l-lactide-co-glycolide)/hydroxyapatite core–shell nanospheres. Part 4: A change of the surface properties during degradation process and the corresponding in vitro cellular response. in Colloids and Surfaces. B: Biointerfaces. 2012;:144-153.
doi:10.1016/j.colsurfb.2011.10.049 .

Vukomanović, Marija, Šarčev, Igor, Petronijević, B., Škapin, Srečo Davor, Ignjatović, Nenad L., Uskoković, Dragan, "Poly(d,l-lactide-co-glycolide)/hydroxyapatite core–shell nanospheres. Part 4: A change of the surface properties during degradation process and the corresponding in vitro cellular response" in Colloids and Surfaces. B: Biointerfaces (2012):144-153,
https://doi.org/10.1016/j.colsurfb.2011.10.049 . .

TY  - CONF
AU  - Veselinović, Ljiljana M.
AU  - Mitrić, Miodrag
AU  - Vukomanović, Marija
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2011
UR  - http://dais.sanu.ac.rs/123456789/161
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7356
AB  - Poster presented at the 13th Annual Conference of the Materials Research Society of Serbia - YUCOMAT 2011, Herceg Novi, Crna Gora, 5–9. septembar 2011.
T1  - Rietveld refinement of barium titanate stannate crystal structure
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7356
ER  - 

@conference{
author = "Veselinović, Ljiljana M. and Mitrić, Miodrag and Vukomanović, Marija and Marković, Smilja and Uskoković, Dragan",
year = "2011",
abstract = "Poster presented at the 13th Annual Conference of the Materials Research Society of Serbia - YUCOMAT 2011, Herceg Novi, Crna Gora, 5–9. septembar 2011.",
title = "Rietveld refinement of barium titanate stannate crystal structure",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7356"
}

Veselinović, L. M., Mitrić, M., Vukomanović, M., Marković, S.,& Uskoković, D.. (2011). Rietveld refinement of barium titanate stannate crystal structure. .
https://hdl.handle.net/21.15107/rcub_vinar_7356

Veselinović LM, Mitrić M, Vukomanović M, Marković S, Uskoković D. Rietveld refinement of barium titanate stannate crystal structure. 2011;.
https://hdl.handle.net/21.15107/rcub_vinar_7356 .

Veselinović, Ljiljana M., Mitrić, Miodrag, Vukomanović, Marija, Marković, Smilja, Uskoković, Dragan, "Rietveld refinement of barium titanate stannate crystal structure" (2011),
https://hdl.handle.net/21.15107/rcub_vinar_7356 .

TY  - CONF
AU  - Veselinović, Ljiljana M.
AU  - Mitrić, Miodrag
AU  - Vukomanović, Marija
AU  - Marković, Smilja
AU  - Uskoković, Dragan
PY  - 2011
UR  - http://dais.sanu.ac.rs/123456789/688
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7511
AB  - The barium titanates have wide application in electronic industry as a dielectric and ferroelectric materials.The BaTiO3 doped with Sn is important for practical application in ceramic capacitors as well as in functionally graded materials. It is known that BaTiO3 materials have the typical perovsikite crystal structural. Their ideal crystal structure is a centrosimetric cubic structure with space group. However, the changes in temperature, pressure, and composition lead to phase transitions and crystal structure transformations. Pm 3m in this study using by Rietveld refinement, we resolved crystal structure of barium titanate stannate (BTS) BaTi1−xSnxO3 (x = 0, 0.025, 0.05, 0.07, 0.10, 0.12, 0.15 and 0.20) solid solutions. The powders were prepared by simple solid state reaction at 1420 oC, in air for 2 hours. The structural investigations of the BTS samples were done at room temperature using an X-ray diffraction, Raman spectroscopy and TEM micrograph. The Rietveld refinement of the X-ray diffraction data was used to analyze the structural changes depending on amount of the Sn4+ ions in the BTS. Obtained data show that increasing of Sn amount in the structure provokes the transformation of crystal structure from tetragonal to cubic one. We suppose that the absence of orthorhombic and rhombohedral phases is probably a consequence of phase (0.025≤x<0.20) stabilization caused by method of sample preparation (high temperature solid state reaction).
PB  - Belgrade : Materials Research Society of Serbia
C3  - The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts
T1  - Rietveld refinement of barium titanate stannate crystal structure
SP  - 136
EP  - 136
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7511
ER  - 

@conference{
author = "Veselinović, Ljiljana M. and Mitrić, Miodrag and Vukomanović, Marija and Marković, Smilja and Uskoković, Dragan",
year = "2011",
abstract = "The barium titanates have wide application in electronic industry as a dielectric and ferroelectric materials.The BaTiO3 doped with Sn is important for practical application in ceramic capacitors as well as in functionally graded materials. It is known that BaTiO3 materials have the typical perovsikite crystal structural. Their ideal crystal structure is a centrosimetric cubic structure with space group. However, the changes in temperature, pressure, and composition lead to phase transitions and crystal structure transformations. Pm 3m in this study using by Rietveld refinement, we resolved crystal structure of barium titanate stannate (BTS) BaTi1−xSnxO3 (x = 0, 0.025, 0.05, 0.07, 0.10, 0.12, 0.15 and 0.20) solid solutions. The powders were prepared by simple solid state reaction at 1420 oC, in air for 2 hours. The structural investigations of the BTS samples were done at room temperature using an X-ray diffraction, Raman spectroscopy and TEM micrograph. The Rietveld refinement of the X-ray diffraction data was used to analyze the structural changes depending on amount of the Sn4+ ions in the BTS. Obtained data show that increasing of Sn amount in the structure provokes the transformation of crystal structure from tetragonal to cubic one. We suppose that the absence of orthorhombic and rhombohedral phases is probably a consequence of phase (0.025≤x<0.20) stabilization caused by method of sample preparation (high temperature solid state reaction).",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts",
title = "Rietveld refinement of barium titanate stannate crystal structure",
pages = "136-136",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7511"
}

Veselinović, L. M., Mitrić, M., Vukomanović, M., Marković, S.,& Uskoković, D.. (2011). Rietveld refinement of barium titanate stannate crystal structure. in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts
Belgrade : Materials Research Society of Serbia., 136-136.
https://hdl.handle.net/21.15107/rcub_vinar_7511

Veselinović LM, Mitrić M, Vukomanović M, Marković S, Uskoković D. Rietveld refinement of barium titanate stannate crystal structure. in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts. 2011;:136-136.
https://hdl.handle.net/21.15107/rcub_vinar_7511 .

Veselinović, Ljiljana M., Mitrić, Miodrag, Vukomanović, Marija, Marković, Smilja, Uskoković, Dragan, "Rietveld refinement of barium titanate stannate crystal structure" in The Thirteenth Annual Conference YUCOMAT 2011: Programme and the Book of Abstracts (2011):136-136,
https://hdl.handle.net/21.15107/rcub_vinar_7511 .

TY  - JOUR
AU  - Vukomanovic, Marija
AU  - Škapin, Srečo Davor
AU  - Jančar, Boštjan
AU  - Maksin, Tatjana N.
AU  - Ignjatović, Nenad L.
AU  - Uskokovic, Vuk
AU  - Uskoković, Dragan
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4188
AB  - Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces. B: Biointerfaces
T1  - Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery
VL  - 82
IS  - 2
SP  - 404
EP  - 413
DO  - 10.1016/j.colsurfb.2010.09.011
ER  - 

@article{
author = "Vukomanovic, Marija and Škapin, Srečo Davor and Jančar, Boštjan and Maksin, Tatjana N. and Ignjatović, Nenad L. and Uskokovic, Vuk and Uskoković, Dragan",
year = "2011",
abstract = "Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) and bioactive hydroxyapatite (HAP) are selected for the formation of a multifunctional system with the specific core-shell structure to be applied as a carrier of a drug. As a result, both components of PLGA/HAp core-shells are able to capture one part of the drug. Polymeric shells consisting of small nanospheres up to 20 nm in size act as a matrix in which one part of the drug is dispersed. In the same time, ceramic cores are formed of rod-like hydroxyapatite particles at the surface of which another part of the drug is adsorbed onto the interface between the polymer and the ceramics. The content of the loaded drug, as well as the selected solvent/non-solvent system, have a crucial influence on the resulting PLGA/HAp morphology and, finally, unimodal distribution of core-shells is obtained. The redistribution of the drug between the organic and inorganic parts of the material is expected to provide an interesting contribution to the kinetics of the drug release resulting in non-typical two-step drug release. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces. B: Biointerfaces",
title = "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery",
volume = "82",
number = "2",
pages = "404-413",
doi = "10.1016/j.colsurfb.2010.09.011"
}

Vukomanovic, M., Škapin, S. D., Jančar, B., Maksin, T. N., Ignjatović, N. L., Uskokovic, V.,& Uskoković, D.. (2011). Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces. B: Biointerfaces, 82(2), 404-413.
https://doi.org/10.1016/j.colsurfb.2010.09.011

Vukomanovic M, Škapin SD, Jančar B, Maksin TN, Ignjatović NL, Uskokovic V, Uskoković D. Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. in Colloids and Surfaces. B: Biointerfaces. 2011;82(2):404-413.
doi:10.1016/j.colsurfb.2010.09.011 .

Vukomanovic, Marija, Škapin, Srečo Davor, Jančar, Boštjan, Maksin, Tatjana N., Ignjatović, Nenad L., Uskokovic, Vuk, Uskoković, Dragan, "Poly(D,L-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery" in Colloids and Surfaces. B: Biointerfaces, 82, no. 2 (2011):404-413,
https://doi.org/10.1016/j.colsurfb.2010.09.011 . .

TY  - CONF
AU  - Vukomanović, Marija
AU  - Škapin, Srečo Davor
AU  - Šarčev, Ivan
AU  - Ignjatović, Nenad L.
AU  - Uskoković, Dragan
PY  - 2010
UR  - http://dais.sanu.ac.rs/123456789/252
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7378
AB  - Poster presented at the Third International “NanoBio – Zurich 2010” Conference, August 2010, Zurich, Switzerland
T1  - Perspectives of novel poly(d,l-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7378
ER  - 

@conference{
author = "Vukomanović, Marija and Škapin, Srečo Davor and Šarčev, Ivan and Ignjatović, Nenad L. and Uskoković, Dragan",
year = "2010",
abstract = "Poster presented at the Third International “NanoBio – Zurich 2010” Conference, August 2010, Zurich, Switzerland",
title = "Perspectives of novel poly(d,l-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7378"
}

Vukomanović, M., Škapin, S. D., Šarčev, I., Ignjatović, N. L.,& Uskoković, D.. (2010). Perspectives of novel poly(d,l-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics. .
https://hdl.handle.net/21.15107/rcub_vinar_7378

Vukomanović M, Škapin SD, Šarčev I, Ignjatović NL, Uskoković D. Perspectives of novel poly(d,l-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics. 2010;.
https://hdl.handle.net/21.15107/rcub_vinar_7378 .

Vukomanović, Marija, Škapin, Srečo Davor, Šarčev, Ivan, Ignjatović, Nenad L., Uskoković, Dragan, "Perspectives of novel poly(d,l-lactide-co-glycolide)/hydroxyapatite core-shell nanoparticles as carriers of antibiotics" (2010),
https://hdl.handle.net/21.15107/rcub_vinar_7378 .

TY  - JOUR
AU  - Vukomanovic, Marija
AU  - Mitrić, Miodrag
AU  - Škapin, Srečo Davor
AU  - Zagar, Ema
AU  - Plavec, Janez
AU  - Ignjatović, Nenad L.
AU  - Uskoković, Dragan
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3943
AB  - In this work poly(D,L-lactide-co-glycolide) (PLGA) and a poly(D,L-lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) composite processed in an ultrasonic field at higher (25 degrees C) and lower (8 degrees C) temperatures were studied with respect to the molecular properties of the obtained materials. The processing of the PLGA and the PLGA/HAp composite in an ultrasonic field resulted in a change of molar mass averages of the polymer/polymeric part of these materials, while an amorphous structure and a 50:50 lactide-to-glycolide co-monomer ratio were preserved without the formation of crystalline oligomers. However, mobility of polymeric chains obtained after ultrasonic processing was lower indicating ordering the structure of polymeric chains as a result of processing. Additionally, it was observed that the mobility of the PLGA macromolecules was lower within the composite in comparison with the mobility of the chains within the PLGA alone in the case when both were obtained after ultrasonic processing. This was a consequence of the structure formation through the interactions between the PLGA and the HAp. Based on these results different degradation rate of PLGA in composite can be expected, which is important in the application of this material for the controlled drug delivery of medicaments. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Ultrasonics Sonochemistry
T1  - Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite
VL  - 17
IS  - 5
SP  - 902
EP  - 908
DO  - 10.1016/j.ultsonch.2010.01.007
ER  - 

@article{
author = "Vukomanovic, Marija and Mitrić, Miodrag and Škapin, Srečo Davor and Zagar, Ema and Plavec, Janez and Ignjatović, Nenad L. and Uskoković, Dragan",
year = "2010",
abstract = "In this work poly(D,L-lactide-co-glycolide) (PLGA) and a poly(D,L-lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) composite processed in an ultrasonic field at higher (25 degrees C) and lower (8 degrees C) temperatures were studied with respect to the molecular properties of the obtained materials. The processing of the PLGA and the PLGA/HAp composite in an ultrasonic field resulted in a change of molar mass averages of the polymer/polymeric part of these materials, while an amorphous structure and a 50:50 lactide-to-glycolide co-monomer ratio were preserved without the formation of crystalline oligomers. However, mobility of polymeric chains obtained after ultrasonic processing was lower indicating ordering the structure of polymeric chains as a result of processing. Additionally, it was observed that the mobility of the PLGA macromolecules was lower within the composite in comparison with the mobility of the chains within the PLGA alone in the case when both were obtained after ultrasonic processing. This was a consequence of the structure formation through the interactions between the PLGA and the HAp. Based on these results different degradation rate of PLGA in composite can be expected, which is important in the application of this material for the controlled drug delivery of medicaments. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Ultrasonics Sonochemistry",
title = "Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite",
volume = "17",
number = "5",
pages = "902-908",
doi = "10.1016/j.ultsonch.2010.01.007"
}

Vukomanovic, M., Mitrić, M., Škapin, S. D., Zagar, E., Plavec, J., Ignjatović, N. L.,& Uskoković, D.. (2010). Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite. in Ultrasonics Sonochemistry, 17(5), 902-908.
https://doi.org/10.1016/j.ultsonch.2010.01.007

Vukomanovic M, Mitrić M, Škapin SD, Zagar E, Plavec J, Ignjatović NL, Uskoković D. Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite. in Ultrasonics Sonochemistry. 2010;17(5):902-908.
doi:10.1016/j.ultsonch.2010.01.007 .

Vukomanovic, Marija, Mitrić, Miodrag, Škapin, Srečo Davor, Zagar, Ema, Plavec, Janez, Ignjatović, Nenad L., Uskoković, Dragan, "Influence of ultrasonic processing on the macromolecular properties of poly (D,L-lactide-co-glycolide) alone and in its biocomposite with hydroxyapatite" in Ultrasonics Sonochemistry, 17, no. 5 (2010):902-908,
https://doi.org/10.1016/j.ultsonch.2010.01.007 . .