TY  - JOUR
AU  - Ognjanović, Miloš
AU  - Stanković, Dalibor M.
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Jančar, Boštjan
AU  - Dojčinović, Biljana P.
AU  - Prijović, Željko
AU  - Antić, Bratislav
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0925838818340684
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7942
AB  - In a new approach based on a two-step procedure, co-precipitation method followed by hydrothermal treatment in a microwave field, Zn-substituted Fe3O4 nanoparticles (ZnxFe3-xO4) were synthesized. Results of XRD, FT–IR and TEM analysis clearly demonstrate that nanoparticles were single phase, crystallizing in the spinel structure type (S.G. Fd3¯m) with crystallite size in the range of 2–20 nm, which strongly depends on Zn concentration. The produced nanoparticles were used for fabrication of modified carbon paste electrodes as a novel system for electrochemical non-enzymatic glucose detection. It was found that the increase of zinc concentration up to the value of x = 0.56 (Zn0.56Fe2.44O4) of as-prepared nanoparticles was followed with an increase of a performance of the modified carbon paste electrode toward glucose detection. Linear working range from 0.1 to 2 mM was obtained with detection limit of 0.03 mM, and with fast response time (<3 s). Proposed sensor was successfully applied for the determination of glucose level in real samples with satisfactory recovery. The synthesized zinc-ferrite samples were also tested as potential heating agents in magnetic hyperthermia. The heating ability (SAR value) increases with x value, reaching maximum for x = 0.37. This is correlated with changes of particle size and magnetic characteristics which strongly depend on Zn concentration. © 2018 Elsevier B.V.
T2  - Journal of Alloys and Compounds
T1  - Bifunctional (Zn,Fe)3O4 nanoparticles: Tuning their efficiency for potential application in reagentless glucose biosensors and magnetic hyperthermia
VL  - 777
SP  - 454
EP  - 462
DO  - 10.1016/j.jallcom.2018.10.369
ER  - 

@article{
author = "Ognjanović, Miloš and Stanković, Dalibor M. and Ming, Yue and Zhang, Hongguo and Jančar, Boštjan and Dojčinović, Biljana P. and Prijović, Željko and Antić, Bratislav",
year = "2019",
abstract = "In a new approach based on a two-step procedure, co-precipitation method followed by hydrothermal treatment in a microwave field, Zn-substituted Fe3O4 nanoparticles (ZnxFe3-xO4) were synthesized. Results of XRD, FT–IR and TEM analysis clearly demonstrate that nanoparticles were single phase, crystallizing in the spinel structure type (S.G. Fd3¯m) with crystallite size in the range of 2–20 nm, which strongly depends on Zn concentration. The produced nanoparticles were used for fabrication of modified carbon paste electrodes as a novel system for electrochemical non-enzymatic glucose detection. It was found that the increase of zinc concentration up to the value of x = 0.56 (Zn0.56Fe2.44O4) of as-prepared nanoparticles was followed with an increase of a performance of the modified carbon paste electrode toward glucose detection. Linear working range from 0.1 to 2 mM was obtained with detection limit of 0.03 mM, and with fast response time (<3 s). Proposed sensor was successfully applied for the determination of glucose level in real samples with satisfactory recovery. The synthesized zinc-ferrite samples were also tested as potential heating agents in magnetic hyperthermia. The heating ability (SAR value) increases with x value, reaching maximum for x = 0.37. This is correlated with changes of particle size and magnetic characteristics which strongly depend on Zn concentration. © 2018 Elsevier B.V.",
journal = "Journal of Alloys and Compounds",
title = "Bifunctional (Zn,Fe)3O4 nanoparticles: Tuning their efficiency for potential application in reagentless glucose biosensors and magnetic hyperthermia",
volume = "777",
pages = "454-462",
doi = "10.1016/j.jallcom.2018.10.369"
}

Ognjanović, M., Stanković, D. M., Ming, Y., Zhang, H., Jančar, B., Dojčinović, B. P., Prijović, Ž.,& Antić, B.. (2019). Bifunctional (Zn,Fe)3O4 nanoparticles: Tuning their efficiency for potential application in reagentless glucose biosensors and magnetic hyperthermia. in Journal of Alloys and Compounds, 777, 454-462.
https://doi.org/10.1016/j.jallcom.2018.10.369

Ognjanović M, Stanković DM, Ming Y, Zhang H, Jančar B, Dojčinović BP, Prijović Ž, Antić B. Bifunctional (Zn,Fe)3O4 nanoparticles: Tuning their efficiency for potential application in reagentless glucose biosensors and magnetic hyperthermia. in Journal of Alloys and Compounds. 2019;777:454-462.
doi:10.1016/j.jallcom.2018.10.369 .

Ognjanović, Miloš, Stanković, Dalibor M., Ming, Yue, Zhang, Hongguo, Jančar, Boštjan, Dojčinović, Biljana P., Prijović, Željko, Antić, Bratislav, "Bifunctional (Zn,Fe)3O4 nanoparticles: Tuning their efficiency for potential application in reagentless glucose biosensors and magnetic hyperthermia" in Journal of Alloys and Compounds, 777 (2019):454-462,
https://doi.org/10.1016/j.jallcom.2018.10.369 . .

TY  - JOUR
AU  - Ognjanović, Miloš
AU  - Spasojević, Irena
AU  - Stanković, Dalibor M.
AU  - Ming, Yue
AU  - Jančar, Boštjan
AU  - Dojčinović, Biljana P.
AU  - Spasojević, Vojislav
AU  - Antić, Bratislav
PY  - 2019
UR  - https://www.ingentaconnect.com/content/10.1166/jnn.2019.16284
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8074
AB  - A series of MgxFe3-xO₄ (x ═ 0-1) nanoparticles was synthesized in order to prepare novel MgxFe3-xO₄/glassy carbon modified electrodes. Effects of magnesium content (x) on the analytical performance of the modified electrodes in the detection of gallic acid were evaluated. It was found that magnesium concentration and crystallite/particle size of the prepared nanoparticles play significant roles in the sensing properties of modified electrodes. The increase of magnesium concentration up to the value of x ═ 0.4 in MgxFe3-xO₄/glassy carbon paste was accompanied by an increase of the corresponding oxidation current of gallic acid. However, further growth of x value caused decline of the obtained oxidation current. An electroanalytical procedure was established, and the analytical performance of the proposed Mg0.4Fe2.6O₄/glassy carbon paste electrode was monitored using previously optimized experimental conditions. A working linear range from 1-39 µM gallic acid was obtained with detection limit of 0.29 µM. According to these results, the developed procedure can be applied for detection of low concentrations of gallic acid with satisfactory selectivity in the presence of some common naturally occurring compounds. Experimental results indicate that the developed procedure could be a novel approach in the detection of antioxidant, overcoming some known disadvantages such as passivation, and could be a promising replacement for sophisticated chromatographic methods.
T2  - Journal of Nanoscience and Nanotechnology
T1  - Enhancing Analytical Performance of (Mg,Fe)3O4/Glassy Carbon Electrodes by Tailoring Chemical Composition of (Mg,Fe)3O4 Nanoparticles
VL  - 19
IS  - 7
SP  - 4205
EP  - 4213
DO  - 10.1166/jnn.2019.16284
ER  - 

@article{
author = "Ognjanović, Miloš and Spasojević, Irena and Stanković, Dalibor M. and Ming, Yue and Jančar, Boštjan and Dojčinović, Biljana P. and Spasojević, Vojislav and Antić, Bratislav",
year = "2019",
abstract = "A series of MgxFe3-xO₄ (x ═ 0-1) nanoparticles was synthesized in order to prepare novel MgxFe3-xO₄/glassy carbon modified electrodes. Effects of magnesium content (x) on the analytical performance of the modified electrodes in the detection of gallic acid were evaluated. It was found that magnesium concentration and crystallite/particle size of the prepared nanoparticles play significant roles in the sensing properties of modified electrodes. The increase of magnesium concentration up to the value of x ═ 0.4 in MgxFe3-xO₄/glassy carbon paste was accompanied by an increase of the corresponding oxidation current of gallic acid. However, further growth of x value caused decline of the obtained oxidation current. An electroanalytical procedure was established, and the analytical performance of the proposed Mg0.4Fe2.6O₄/glassy carbon paste electrode was monitored using previously optimized experimental conditions. A working linear range from 1-39 µM gallic acid was obtained with detection limit of 0.29 µM. According to these results, the developed procedure can be applied for detection of low concentrations of gallic acid with satisfactory selectivity in the presence of some common naturally occurring compounds. Experimental results indicate that the developed procedure could be a novel approach in the detection of antioxidant, overcoming some known disadvantages such as passivation, and could be a promising replacement for sophisticated chromatographic methods.",
journal = "Journal of Nanoscience and Nanotechnology",
title = "Enhancing Analytical Performance of (Mg,Fe)3O4/Glassy Carbon Electrodes by Tailoring Chemical Composition of (Mg,Fe)3O4 Nanoparticles",
volume = "19",
number = "7",
pages = "4205-4213",
doi = "10.1166/jnn.2019.16284"
}

Ognjanović, M., Spasojević, I., Stanković, D. M., Ming, Y., Jančar, B., Dojčinović, B. P., Spasojević, V.,& Antić, B.. (2019). Enhancing Analytical Performance of (Mg,Fe)3O4/Glassy Carbon Electrodes by Tailoring Chemical Composition of (Mg,Fe)3O4 Nanoparticles. in Journal of Nanoscience and Nanotechnology, 19(7), 4205-4213.
https://doi.org/10.1166/jnn.2019.16284

Ognjanović M, Spasojević I, Stanković DM, Ming Y, Jančar B, Dojčinović BP, Spasojević V, Antić B. Enhancing Analytical Performance of (Mg,Fe)3O4/Glassy Carbon Electrodes by Tailoring Chemical Composition of (Mg,Fe)3O4 Nanoparticles. in Journal of Nanoscience and Nanotechnology. 2019;19(7):4205-4213.
doi:10.1166/jnn.2019.16284 .

Ognjanović, Miloš, Spasojević, Irena, Stanković, Dalibor M., Ming, Yue, Jančar, Boštjan, Dojčinović, Biljana P., Spasojević, Vojislav, Antić, Bratislav, "Enhancing Analytical Performance of (Mg,Fe)3O4/Glassy Carbon Electrodes by Tailoring Chemical Composition of (Mg,Fe)3O4 Nanoparticles" in Journal of Nanoscience and Nanotechnology, 19, no. 7 (2019):4205-4213,
https://doi.org/10.1166/jnn.2019.16284 . .

TY  - JOUR
AU  - Antić, Bratislav
AU  - Bošković, Marko
AU  - Nikodinović-Runić, Jasmina
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Božin, Emil S.
AU  - Janković, Drina
AU  - Spasojević, Vojislav
AU  - Vranješ-Đurić, Sanja
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1551
AB  - Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems. (C) 2017 Elsevier B.V. All rights reserved.
T2  - Materials Science and Engineering. C: Materials for Biological Applications
T1  - Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles
VL  - 75
SP  - 157
EP  - 164
DO  - 10.1016/j.msec.2017.02.023
ER  - 

@article{
author = "Antić, Bratislav and Bošković, Marko and Nikodinović-Runić, Jasmina and Ming, Yue and Zhang, Hongguo and Božin, Emil S. and Janković, Drina and Spasojević, Vojislav and Vranješ-Đurić, Sanja",
year = "2017",
abstract = "Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems. (C) 2017 Elsevier B.V. All rights reserved.",
journal = "Materials Science and Engineering. C: Materials for Biological Applications",
title = "Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles",
volume = "75",
pages = "157-164",
doi = "10.1016/j.msec.2017.02.023"
}

Antić, B., Bošković, M., Nikodinović-Runić, J., Ming, Y., Zhang, H., Božin, E. S., Janković, D., Spasojević, V.,& Vranješ-Đurić, S.. (2017). Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles. in Materials Science and Engineering. C: Materials for Biological Applications, 75, 157-164.
https://doi.org/10.1016/j.msec.2017.02.023

Antić B, Bošković M, Nikodinović-Runić J, Ming Y, Zhang H, Božin ES, Janković D, Spasojević V, Vranješ-Đurić S. Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles. in Materials Science and Engineering. C: Materials for Biological Applications. 2017;75:157-164.
doi:10.1016/j.msec.2017.02.023 .

Antić, Bratislav, Bošković, Marko, Nikodinović-Runić, Jasmina, Ming, Yue, Zhang, Hongguo, Božin, Emil S., Janković, Drina, Spasojević, Vojislav, Vranješ-Đurić, Sanja, "Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles" in Materials Science and Engineering. C: Materials for Biological Applications, 75 (2017):157-164,
https://doi.org/10.1016/j.msec.2017.02.023 . .