Cakić, Nevenka D.

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Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity

Radulović, Niko S.; Ranđelović, Pavle J.; Stojanović, Nikola M.; Cakić, Nevenka D.; Bogdanović, Goran A.; Živanović, Ana V.

(2015)

TY  - JOUR
AU  - Radulović, Niko S.
AU  - Ranđelović, Pavle J.
AU  - Stojanović, Nikola M.
AU  - Cakić, Nevenka D.
AU  - Bogdanović, Goran A.
AU  - Živanović, Ana V.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/874
AB  - Callistemon citrinus (Myrtaceae) is a shrub native to Australia. Its flowers have been used as indigenous food among the aboriginal Australians. Numerous diseases, such as bacterial, fungal, viral and parasite infections have traditionally been treated with this plant. Gas chromatography mass spectrometry (GC/MS) analyses of the flower and leaf extracts of C citrinus revealed the presence of a major constituent, a phloroglucinol, dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one (1) (up to 382.2 mg per 1 g of the flower extracts). Compound 1 was for the first time identified in this genus. This phloroglucinol exhibited potent antinociceptive and anti-inflammatory activities in a dose-dependent manner. In addition, this compound displayed strong in vitro antioxidant activity which could be easily connected with both anti-inflammatory and antinociceptive effects. Thus, compound 1, as a plant constituent present in the diet of Aboriginal people, that helps with inflammation and pain, could have given them a better chance of survival in harsh conditions of the environment. (C) 2015 Elsevier Ltd. All rights reserved.
T2  - Food Research International
T1  - Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity
VL  - 77
IS  - SI
SP  - 280
EP  - 289
DO  - 10.1016/j.foodres.2015.02.023
ER  - 
@article{
author = "Radulović, Niko S. and Ranđelović, Pavle J. and Stojanović, Nikola M. and Cakić, Nevenka D. and Bogdanović, Goran A. and Živanović, Ana V.",
year = "2015",
abstract = "Callistemon citrinus (Myrtaceae) is a shrub native to Australia. Its flowers have been used as indigenous food among the aboriginal Australians. Numerous diseases, such as bacterial, fungal, viral and parasite infections have traditionally been treated with this plant. Gas chromatography mass spectrometry (GC/MS) analyses of the flower and leaf extracts of C citrinus revealed the presence of a major constituent, a phloroglucinol, dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one (1) (up to 382.2 mg per 1 g of the flower extracts). Compound 1 was for the first time identified in this genus. This phloroglucinol exhibited potent antinociceptive and anti-inflammatory activities in a dose-dependent manner. In addition, this compound displayed strong in vitro antioxidant activity which could be easily connected with both anti-inflammatory and antinociceptive effects. Thus, compound 1, as a plant constituent present in the diet of Aboriginal people, that helps with inflammation and pain, could have given them a better chance of survival in harsh conditions of the environment. (C) 2015 Elsevier Ltd. All rights reserved.",
journal = "Food Research International",
title = "Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity",
volume = "77",
number = "SI",
pages = "280-289",
doi = "10.1016/j.foodres.2015.02.023"
}
Radulović, N. S., Ranđelović, P. J., Stojanović, N. M., Cakić, N. D., Bogdanović, G. A.,& Živanović, A. V.. (2015). Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity. in Food Research International, 77(SI), 280-289.
https://doi.org/10.1016/j.foodres.2015.02.023
Radulović NS, Ranđelović PJ, Stojanović NM, Cakić ND, Bogdanović GA, Živanović AV. Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity. in Food Research International. 2015;77(SI):280-289.
doi:10.1016/j.foodres.2015.02.023 .
Radulović, Niko S., Ranđelović, Pavle J., Stojanović, Nikola M., Cakić, Nevenka D., Bogdanović, Goran A., Živanović, Ana V., "Aboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activity" in Food Research International, 77, no. SI (2015):280-289,
https://doi.org/10.1016/j.foodres.2015.02.023 . .
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